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5-Amino-4-imidazolecarboxamide Hydrochloride
5-Amino-4-imidazolecarboxamide hydrochloride is the hydrochloride salt of 5-Amino-4-imidazolecarboxamide, a metabolite of Temozolomide. It is also an impurity in the synthesis of Dacarbazine. Synonyms: 4-amino-1H-imidazole-5-carboxamide;hydrochloride; 4-amino-1H-imidazole-5-carboxamide;hydrochloride. Grades: > 95 %. CAS No. 72-40-2. Molecular formula: C4H7ClN4O. Mole weight: 162.58.
5-Aza-2'-deoxy Cytidine Diphosphate
5-Aza-2'-deoxy Cytidine Diphosphate is a derivative of Decitabine, which is a potent inhibitor of DNA methylation used to treat myelodysplastic syndromes (MDS). Synonyms: ((2R,3S,5R)-5-(4-amino-2-oxo-1,3,5-triazin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl trihydrogen diphosphate; 4-Amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-1,3,5-triazin-2(1H)-one Diphosphate; 2-Desoxy-5-azacytidine Diphosphate; 2'-Deoxy-5-azacytidine Diphosphate; DAC Diphosphate; Dacogen Diphosphate; Decitabine Diphosphate; NSC 127716 Diphosphate; β-Decitabine Diphosphate; 4-Amino-1-{2-deoxy-5-O-[hydroxy(phosphonooxy)phosphoryl]-β-D-erythro-pentofuranosyl}-1,3,5-triazin-2(1H)-one. Molecular formula: C8H14N4O10P2. Mole weight: 388.16.
5-Azido Oseltamivir
5-Azido Oseltamivir is an intermediate of Oseltamivir, which can be used in COVID19-related research. Uses: Intermediate in the production of oseltamivir. Synonyms: [3R-(3α,4β,5α)]-4-(Acetylamino)-5-azido-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylic Acid Ethyl Ester; (3R,4R,5S)-4-(Acetylamino)-5-azido-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylic Acid Ethyl Ester. Grades: ≥95%. CAS No. 204255-06-1. Molecular formula: C16H26N4O4. Mole weight: 338.40.
5β-4,5-Dihydro Prednisolone 21-Acetate
5β-4,5-Dihydro Prednisolone 21-Acetate is a derivative of Prednisolone, which is a synthetic glucocorticoid, a derivative of cortisol, and can be used to treat a variety of inflammatory and auto-immune conditions. Synonyms: 11β,17,21-Trihydroxy-5α-pregn-1-ene-3,20-dione 21-Acetate; 5α-Pregn-1-ene-3,20-dione, 11β,17,21-trihydroxy-, 21-acetate; (5β,11β)-11,17-Dihydroxy-3,20-dioxopregn-1-en-21-yl acetate; Pregn-1-ene-3,20-dione, 21-(acetyloxy)-11,17-dihydroxy-, (5β,11β)-. CAS No. 114127-54-7. Molecular formula: C23H32O6. Mole weight: 404.50.
5β/6β-Hydroxy Lurasidone Hydrochloride(Mixture of Diastereomers)
5-Beta-Dutasteride
5-Beta-Dutasteride is the β-isomer impurity of Dutasteride. Synonyms: (4aR,4bS,6aS,7S,9aS,9bS,11aS)-N-[2,5-Bis(trifluoromethyl)phenyl]-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxamide; (5β,17β)-N-[2,5-Bis(trifluoromethyl)phenyl]-3-oxo-4-azaandrost-1-ene-17-carb. Grades: > 95%. CAS No. 957229-52-6. Molecular formula: C27H30F6N2O2. Mole weight: 528.53.
5β-Finasteride
An impurity of Finasteride. Finasteride is a 4-azasteroid analog of testosterone that competitively blocks type II 5α-reductase activity with 100-fold greater affinity than for the type I enzyme. Synonyms: (4aR,4bS,6aS,7S,9aS,9bS,11aS)-N-(1,1-Dimethylethyl)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxamide; (5β,17β)-N-(1,1-dimethylethyl)-3-oxo-4-Azaandrost-1-ene-17-carboxamide. Grades: > 95%. CAS No. 140375-22-0. Molecular formula: C23H36N2O2. Mole weight: 372.56.
5-Beta-Hydroxy-Drospirenone-17-Propanol
5-Hydroxy Drospirenone Ring-opened Alcohol Impurity is an impurity of Drospirenone. Synonyms: (5R, 6R, 7R, 8R, 9S, 10R, 13S, 14S, 15S, 16S, 17S)-Octadecahydro-5, 17-dihydroxy-17-(3-hydroxypropyl)-10, 13-dimethyl-3H-dicyclopropa[6, 7:15, 16]cyclopenta[a]phenanthren-3-one; 17α-[3-Hydroxypropyl]-6β,7β:15β,16β-dimethylen-5β-androstan-5,17β-ol-3-one. Grades: > 95%. CAS No. 1357252-81-3. Molecular formula: C24H36O4. Mole weight: 388.54.
(5-bromo-2-chlorophenyl)(4-fluorophenyl)methanone
(5-bromo-2-chlorophenyl)(4-fluorophenyl)methanone is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: (5-bromo-2-chlorophenyl)(4-fluorophenyl)methanone; 915095-85-1; (5-bromo-2-chlorophenyl)-(4-fluorophenyl)methanone; C13H7BrClFO; SCHEMBL2637828; AMY39947; MFCD12410140; AKOS005831751; 5-Bromo-2-Chloro-4'-Fluorobenzophenone; BS-17834; CS-0162265; D84028; (5-bromo-2-chlorophenyl)(4-fluorophenyl) methanone; Methanone, (5-bromo-2-chlorophenyl)(4-fluorophenyl)-. CAS No. 915095-85-1. Molecular formula: C13H7BrClFO. Mole weight: 313.55.
5-bromo-4-chloro-N-cyclopentylpyrimidin-2-amine
An impurity of Palbociclib, a selective inhibitor of cyclin-dependent kinases CDK4 and CDK6. Palbociclib is developed for the treatment of ER-positive and HER2-negative breast cancer. Synonyms: 5-Bromo-4-chloro-N-cyclopentylpyrimidin-2-amine; 1823404-28-9; CS-0011349; D87404; 5-?Bromo-?4-?chloro-?N-?cyclopentylpyrimidin?-?2-?amine. CAS No. 1823404-28-9. Molecular formula: C9H11BrClN3. Mole weight: 276.56.
5-(Bromomethyl)-2,4-dichlorothiazole
5-(Bromomethyl)-2,4-dichlorothiazole is an intermediate for the synthesis of Thiamethoxam, which is a neonicotinoid insecticide. Synonyms: Thiazole, 5-(bromomethyl)-2,4-dichloro-. CAS No. 358672-75-0. Molecular formula: C4H2BrCl2NS. Mole weight: 246.94.
An impurity of Etoricoxib. Etoricoxib is a selective COX-2 inhibitor. Synonyms: 3-[4-(Methylthio)phenyl]-5-chloro-6'-methyl-2,3'-bipyridine; Etoricoxib B; 5-chloro-6'-methyl-3-(4-(methylthio)phenyl)-2,3'-bipyridine. Grades: ≥95%. CAS No. 292067-97-1. Molecular formula: C18H15ClN2S. Mole weight: 326.84.
5-Chloro-2-(methylamino)benzophenone
5-Chloro-2-(methylamino)benzophenone is a decompoition product of Diazepam, which is a benzodiazepine used as an anti-anxiety and muscle relaxant, as well as to treat epilepsy. Synonyms: (5-Chloro-2- (methylamino)phenyl) (phenyl)methanone; 2-Methylamino-5-chlorobenzophenone; Ro 5-4365; USP Temazepam Impurity A; Methanone, [5-chloro-2-(methylamino)phenyl]phenyl-; Temazepam EP Impurity A; Diazepam EP Impurity D; Diazepam Related Compound A. Grades: ≥95%. CAS No. 1022-13-5. Molecular formula: C14H12ClNO. Mole weight: 245.70.
1-Chloroacetyl-2-[[ (2-benzoyl-4-chlorophenyl) (2-chloroacetyl) amino]methylene]hydrazide is one of Diazepam metabolites. Diazepam is a benzodiazepine used as an anti-anxiety and muscle relaxant, as well as to treat epilepsy. Synonyms: 2-Chloroacetic Acid 2-[[ (2-Benzoyl-4-chlorophenyl) (2-chloroacetyl) amino]methylene]hydrazide; Chloroacetic Acid [[ (2-Benzoyl-4-chlorophenyl) (chloroacetyl) amino]methylene]hydrazide; (E) -N- (2-Benzoyl-4-chlorophenyl) -2-chloro-N- ( (2- (2-chloroacetyl) hydrazono) methyl) acetamide; Estazolam Impurity 2; 1-Chloroacetyl-2-[[ (2-benzoyl-4-chlorophenyl) (2-chloroacetyl) amino]methylene]hydrazide. Grades: ≥95%. CAS No. 49691-65-8. Molecular formula: C18H14Cl3N3O3. Mole weight: 426.68.
5-Chloro-3-(4-hydroxyphenyl)-2,1-benzisoxazole
5-Chloro-3-(4-hydroxyphenyl)-2,1-benzisoxazole is one of Diazepam intermediates. Diazepam is a benzodiazepine used as an anti-anxiety and muscle relaxant, as well as to treat epilepsy. Synonyms: p-(5-chloro-2,1-benzisoxazol-3-yl)phenol; 4-(5-chloro-benzo[c]isoxazol-3-yl)-phenol; 5-Chlor-3-p-hydroxy-phenyl-anthranil; 3-[4'-Hydroxy-phenyl]-5-chlor-anthranil. Grades: ≥95%. CAS No. 67445-85-6. Molecular formula: C13H8ClNO2. Mole weight: 245.66.
One of the impurities of Tipiracil, which is a thymidine phosphorylase (TPase) inhibitor and has been found to be a potential drug candidate for metastatic colorectal cancer. Synonyms: Tipiracil Impurity C. Grades: ≥95%. CAS No. 2101241-71-6. Molecular formula: C9H12ClN3O3. Mole weight: 245.66.
5-Chloro Bupropion Fumarate
5-Chloro Bupropion Fumarate is a derivative of Bupropion, which is a selective dopamine uptake inhibitor used in the treatment of depression and smoking cessation. Synonyms: 1-(3,5-Dichlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone (2E)-2-Butenedioate; 1-(3,5-Dichlorophenyl)-2-[(2-methyl-2-propanyl)amino]-1-propanone (2E)-2-butenedioate (1:1); 1-Propanone, 1-(3,5-dichlorophenyl)-2-[(1,1-dimethylethyl)amino]-, (2E)-2-butenedioate (1:1). Grades: 98%. CAS No. 1193779-50-8. Molecular formula: C17H21Cl2NO5. Mole weight: 390.26.
5-Chloro Hydrochlorothiazide
5-Chloro Hydrochlorothiazide is a hydrochlorothiazide derivative. Hydrochlorothiazide is a diuretic medication commonly used to treat high blood pressure. Synonyms: 5,6-Dichloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonaMide 1,1-Dioxide; 5-Chlorohydrochlorothiazide Impurity; Hydrochlorothiazide 5-Chloro Impurity. Grades: > 95%. CAS No. 5233-42-1. Molecular formula: C7H7Cl2N3O4S2. Mole weight: 332.19.
5-Chloromethyl-2H-1,2,4-triazolin-3-one
5-Chloromethyl-2H-1,2,4-triazolin-3-one is an intermediate of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: 5-(Chloromethyl)-1,2-dihydro-3H-1,2,4-triazol-3-one; 5-(Chloromethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one; 5-Chloromethyl-2,3-dihydro-4H-1,2,4-triazol-3-one; 3-Chloromethyl-1,2,4-triazolin-5-one. Grades: ≥95%. CAS No. 252742-72-6. Molecular formula: C3H4ClN3O. Mole weight: 133.54.
5-chloro-N-(4-(5-morpholino-6-oxo-3,6-dihydropyridin-1(2H)-yl)phenyl)pentanamide is an impurity of Apixaban, a direct factor Xa inhibitor used as an anticoagulant for the prevention of venous thromboembolism and stroke in atrial fibrillation. Synonyms: 5-Chloro-N-{4-[5-(4-morpholinyl)-6-oxo-3,6-dihydro-1(2H)-pyridinyl]phenyl}pentanamide; 5-Chloro-N-(4-(3-morpholino-2-oxo-5,6-dihydropyridin-1(2H)-yl)phenyl)pentanamide; 5-Chloropentanamide Apixaban. CAS No. 1643330-62-4. Molecular formula: C20H26ClN3O3. Mole weight: 391.89.
5-Chlorouracil
Fluorouracil Impurity E has the potential to treat neoplastic and viral diseases. Uses: Used for the experimental and clinical treatment of neoplastic and viral diseases. fluorouracil ep impurity e. Synonyms: 5-chloro-1H-pyrimidine-2,4-dione. Grades: > 95 %. CAS No. 1820-81-1. Molecular formula: C4H3ClN2O2. Mole weight: 146.53.
5-Desmethoxy-7-methoxy Donepezil Hydrochloride
5-Desmethoxy-7-methoxy Donepezil Hydrochloride is a derivative of Donepezil, which is a highly specific reversible acetylcholinesterase (AChE) inhibitor used to treat moderate to severe Alzheimer's disease. Synonyms: 2-((1-Benzylpiperidin-4-yl)methyl)-6,7-dimethoxy-2,3-dihydro-1H-inden-1-one hydrochloride; 2,3-Dihydro-6,7-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one Hydrochloride; 2-[(1-Benzyl-4-piperidinyl)methyl]-6,7-dimethoxy-1-indanone hydrochloride (1:1); 1H-Inden-1-one, 2,3-dihydro-6,7-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-, hydrochloride (1:1). Grades: 98%. CAS No. 120013-51-6. Molecular formula: C24H29NO3.HCl. Mole weight: 415.95.
5-(difluoromethoxy)-1H-benzo[d]imidazol-2-ol
An impurity of Pantoprazole which is a proton pump inhibitor used to treat erosive esophagitis (damage to the esophagus from stomach acid), and other conditions involving excess stomach acid such as Zollinger-Ellison syndrome. Synonyms: 2H-Benzimidazol-2-one, 5-(difluoromethoxy)-1,3-dihydro-; Pantoprazole impurity 19. CAS No. 1806469-15-7. Molecular formula: C8H6F2N2O2. Mole weight: 200.14.
(5E)-7-[(1R,2R,3R,5S)-3,5-Bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-[(1E,3S)-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-5-phenyl-1-penten-1-yl]cyclopentyl]-N-ethyl-5-heptenamide is one of bimatoprost intermediates. Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Synonyms: (5E)-7-{(1R,2R,3R,5S)-3,5-Bis{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-[(1E,3S)-3-{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-5-phenyl-1-penten-1-yl]cyclopentyl}-N-ethyl-5-heptenamide; 5-Heptenamide, 7-[(1R,2R,3R,5S)-3,5-bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-[(1E,3S)-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-5-phenyl-1-penten-1-yl]cyclopentyl]-N-ethyl-, (5E)-. Molecular formula: C43H79NO4Si3. Mole weight: 758.35.
5-epi-Emtricitabine
5-epi Emtricitabine is an epimer of Emtricitabine. Synonyms: 4-Amino-5-fluoro-1-[(2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone. Grades: > 95%. CAS No. 145986-26-1. Molecular formula: C8H10FN3O3S. Mole weight: 247.25.
An impurity of Amlodipine. Amlodipine is a long-acting dihydropyridine L-type calcium channel blocker. Amlodipine is used to lower blood pressure and prevent chest pain. CAS No. 2170716-02-4. Molecular formula: C22H29ClN2O5. Mole weight: 436.93.
5-Ethynyl Nicotine
. Uses: An intermediate of nicotinic acetylcholine receptor agonist sib-1508y. used for the treatment of neurological disorders. Synonyms: 3-Ethynyl-5-[(2S)-1-methyl-2-pyrrolidinyl]pyridine;(S)-3-Ethynyl-5-(1-methyl-2-pyrrolidinyl)pyridine; Altinicline; SIB 1508. Grades: 96%. CAS No. 179120-92-4. Molecular formula: C12H14N2. Mole weight: 186.25.
5-Fluoro-2'-deoxyuridine-5'-triphosphate (triethylammonium salt form)
An impurity of UTP. UTP is a pyrimidine nucleoside triphosphate as a substrate in the biosynthesis of RNA. Synonyms: FdUTP (triethylammonium salt form). Grades: 95%. CAS No. 1621676-99-0. Molecular formula: C9H14N2O14P3F.C6H15N. Mole weight: 486.135 (free acid).
5-Fluoro-2-ethoxy-4(1H)pyrimidinone
Fluorouracil Impurity F is a derivative of 5-fluorouracil. Uses: Ethoxy-5-fluoro-4(3h)-pyrimidinone (fluorouracil ep impurity f) is a derivative of 5-fluorouracil (3c,15n2 labelled, f596002) which is a potent antineoplastic agent in clinical use. Synonyms: 2-ethoxy-5-fluoro-1H-pyrimidin-6-one. Grades: > 95 %. CAS No. 56177-80-1. Molecular formula: C6H7FN2O2. Mole weight: 158.13.
The triethylammonium salt form of 5-Fluorouridine-5'-triphosphate. 5-Fluorouridine-5'-triphosphate is a nucleotide with an antimetabolic activity against cancers. Synonyms: FUTP (triethylammonium salt form); 5-fluorouridine triphosphate triethylammonium. Grades: 95%. CAS No. 154962-77-3. Molecular formula: C9H14FN2O15P3.C6H15N. Mole weight: 502.134 (free acid).
5H-Dibenz[b,f]azepin-2-ol is an intermediate of Carbamazepine related compounds. Synonyms: 2-Hydroxyiminostilbene. Grades: ≥95%. CAS No. 81861-18-9. Molecular formula: C14H11NO. Mole weight: 209.24.
5H-Dibenzo[a,d][7]annulen-5-one
5-Dibenzosuberenone can be used in the synthesis of a series of potent antidepressants. Synonyms: 2-tricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,9,11,13-heptaenone; tricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,9,11,13-heptaen-2-one. Grades: > 95 %. CAS No. 2222-33-5. Molecular formula: C15H10O. Mole weight: 206.24.
5-HT3 antagonist 5
5-HT3 antagonist 5 is a 5-HT3 receptor antagonist with anti-depressant activity. Synonyms: N-(4-methoxyphenyl)-2-quinoxalinecarboxamide. CAS No. 901599-43-7. Molecular formula: C16H13N3O2. Mole weight: 279.29.
5-Hydroxy Albuterol
An impurity of Levalbuterol. Levalbuterol is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. It is 29 times more selective for beta2 receptors than beta1 receptors giving it higher specificity for pulmonary beta receptors versus beta1-adrenergic receptors located in the heart. Synonyms: α1-[[(1,1-Dimethylethyl)amino]methyl]-4,5-dihydroxy-1,3-benzenedimethanol; 5-Hydroxyalbuterol; USP Levalbuterol Related Compound G. Grades: > 95%. CAS No. 182676-90-0. Molecular formula: C13H21NO4. Mole weight: 255.32.
5-Hydroxy Coumarin
5-Hydroxy Coumarin is a metabolite of Coumarin. Synonyms: 5-hydroxy-2H-chromen-2-one. Grades: > 95%. CAS No. 6093-67-0. Molecular formula: C9H6O3. Mole weight: 162.14.
5-Hydroxy Dantrolene
5-Hydroxy Dantrolene is a metabolite of Dantrolene that has shown to have muscle relaxant effects. Synonyms: 5-Hydroxy-1-[[[5-(4-nitrophenyl)-2-furanyl]methylene]amino]-2,4-imidazolidinedione. Grades: > 95%. CAS No. 52130-25-3. Molecular formula: C14H10N4O6. Mole weight: 330.25.
5-Hydroxy Duloxetine
5-Hydroxy Duloxetine is a metabolite of Duloxetine, which is a serotonin-norepinephrine reuptake inhibitor used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, neuropathic pain and central sensitization. Synonyms: 5-Hydroxyduloxetine; 5-[(1S)-3-(Methylamino)-1-(2-thienyl)propoxy]-1-naphthalenol; 1-Naphthalenol, 5-[(1S)-3-(methylamino)-1-(2-thienyl)propoxy]-; 5-((S)-3-Methylamino-1-thiophen-2-yl-propoxy)-naphthalen-1-ol; Duloxetine 5-Hydroxy. CAS No. 741693-77-6. Molecular formula: C18H19NO2S. Mole weight: 313.41.
5-Hydroxy Lornoxicam
5-Hydroxy Lornoxicam is one of lornoxicam metabolites. Lornoxicam is a non-steroidal COX-1/COX-2 inhibitor and a non-steroidal anti-inflammatory drug (NSAID), with analgesic, anti-pyretic, anti-thrombotic and anti-inflammatory activities. Synonyms: 6-Chloro-4-hydroxy-N-(5-hydroxy-2-pyridinyl)-2-methyl-2H-thieno[2,3-e]-1,2-thiazine-3-carboxamide 1,1-Dioxide; 2H-Thieno(2,3-e)-1,2-thiazine-3-carboxamide, 6-chloro-4-hydroxy-N-(5-hydroxy-2-pyridinyl)-2-methyl-, 1,1-dioxide. Grades: 98%. CAS No. 123252-96-0. Molecular formula: C13H10ClN3O5S2. Mole weight: 387.82.
5-Hydroxymethyl Flucloxacillin
An impurity of Flucloxacillin. Flucloxacillin is a narrow-spectrum beta-lactam antibiotic of the penicillin class. Synonyms: 5-Hydroxymethyl Flucloxacillin; (2S,5R,6R)-6-[[[3-(2-Chloro-6-fluorophenyl)-5-(hydroxymethyl)-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid. Grades: > 95%. CAS No. 75524-31-1. Molecular formula: C19H16ClFN3O6S Na. Mole weight: 468.87 22.99.
5-hydroxytryptophan
5-Hydroxytryptophan (5-HTP), also known as oxitriptan (INN), is a naturally occurring amino acid and chemical precursor for the treatment of depression. 5-Hydroxytryptophan can be used as a dietary supplement (health product). Uses: Antidepressant. Synonyms: 5-Hydroxy-DL-tryptophan; DL-5-Hydroxytryptophan; H-DL-Trp(5-OH)-OH; (±)-5-Hydroxytryptophan; Tryptophan, 5-hydroxy-; 5-HTP; 5-Hydroxytryptophane; DL-5-HTP; DL-Hydroxytryptophan; NSC 92523. Grades: >98%. CAS No. 56-69-9. Molecular formula: C11H12N2O3. Mole weight: 220.22.
5-Methoxy-3-methyl-2-pyridinecarbonitrile
5-Methoxy-3-methyl-2-pyridinecarbonitrile is one of loratadine intermediates. Loratadine is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Synonyms: 5-Methoxy-3-methylpicolinonitrile; 2-Pyridinecarbonitrile, 5-methoxy-3-methyl-; 2-Cyano-5-methoxy-3-methylpyridine. Grades: ≥95%. CAS No. 1256792-12-7. Molecular formula: C8H8N2O. Mole weight: 148.16.
5-Methoxy-4-Trifluoromethyl Valerophenone
Cas No. 61718-80-7.
5-Methyl-2-(phenylsulfonyl)thiazole
5-Methyl-2-(phenylsulfonyl)thiazole is an intermediate for the synthesis of Thiamethoxam, which is a neonicotinoid insecticide. Molecular formula: C10H9NO2S2. Mole weight: 239.31.
5-Methyl-3,4-diphenyl-4,5-dihydroisoxazol-5-ol
An intermediate for the preparation of Valdecoxib. Valdecoxib is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, rheumatoid arthritis, etc. Valdecoxib exhibits a selectively inhibitory effect of cyclooxygenase-2. Uses: Intermediate for the preparation of valdecoxib. Synonyms: 4,5-Dihydro-5-methyl-3,4-diphenyl-5-isoxazolol. CAS No. 181696-73-1. Molecular formula: C16H15NO2. Mole weight: 253.30.
5''''-Methyl-apixaban
5''''-Methyl-apixaban is an impurity of Apixaban, a direct factor Xa inhibitor used as an anticoagulant for the prevention of venous thromboembolism and stroke in atrial fibrillation. Synonyms: 1-(4-methoxyphenyl)-6-(4-(5-methyl-2-oxopiperidin-1-yl)phenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide; 1-(4-Methoxyphenyl)-6-[4-(5-methyl-2-oxo-1-piperidinyl)phenyl]-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide. CAS No. 1686149-74-5. Molecular formula: C26H27N5O4. Mole weight: 473.52.
5-Methyltetrahydrofolic Acid Calcium Salt Hydrate
5-Methyltetrahydrofolic Acid Calcium Salt Hydrate is a metabolite of Folic acid, which is used to treat anemia caused by folate deficiency. Synonyms: N-[4-[[(2-Amino-3,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic Acid Calcium Hydrate; N-Methyltetrahydrofolate Calcium Hydrate; N5-Methyltetrahydrofolate Calcium Hydrate; N5-Methyltetrahydropteroylglutamate Calcium Hydrate; Prefolic A. Grades: 95%. Molecular formula: C20H23CaN7O6.xH2O. Mole weight: 497.52 (anhydrous).
5-Nitrobenzene-1,3-Dicarboxylic Acid
Cas No. 618-88-2.
5-O-Desmethyl Donepezil
A metabolite of Donepezil. Synonyms: 1-Benzyl-4-[(5-hydroxy-6-methoxy-1-oxo-indan-2-yl)methylpiperidine. Grades: > 95%. CAS No. 120013-57-2. Molecular formula: C23H27NO3. Mole weight: 365.47.
(5R,6R)-6-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3-morpholinone is a diastereomeric byproduct in the preparation of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Uses: A diastereomeric byproduct formed during the synthesis of aprepitant metabolites. Synonyms: 3-Morpholinone, 6-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-, (5R,6R)-; Aprepitant M2 Metabolite 5-Epimer. Grades: ≥95%. CAS No. 419574-33-7. Molecular formula: C20H16F7NO3. Mole weight: 451.33.
5R,6R-Benzylpenicilloate Disodium Salt
5R,6R-Benzylpenicilloate Disodium Salt is the β-lactamase cleavage product/metabolite of antibiotic Penicillin G. Synonyms: [2R-[2α(R*),4β]]-4-carboxy-5,5-dimethyl-α-[(phenylacetyl)amino]-2-thiazolidineacetic Acid Disodium Salt; (αR,2R,4S)-4-Carboxy-5,5-dimethyl-α-[(2-phenylacetyl)amino]-2-Thiazolidineacetic Acid Sodium Salt. CAS No. 63448-72-6. Molecular formula: C16H18N2Na2O5S. Mole weight: 396.37.
5R,6R-Benzylpenicilloic Acid
5R,6R-Benzylpenicilloic Acid is the β-lactamase cleavage product/metabolite of antibiotic Penicillin G. Synonyms: (αR,2R,4S)-4-Carboxy-5,5-dimethyl-α-[(2-phenylacetyl)amino]-2-thiazolidineacetic Acid; [2R-[2α(R*),4β]]-4-Carboxy-5,5-dimethyl-α-[(phenylacetyl)amino]-2-thiazolidineacetic Acid; Benzyl Penicilloic Acid (Mixture of Diastereomers); D-benzylpenicilloic acid; Benzylpenicilloic acid; 4-carboxy-5,5-dimethyl-alpha-((phenylacetyl)amino)-2-thiazolidineacetic acid. Grades: 97%. CAS No. 87492-68-0. Molecular formula: C16H20N2O5S. Mole weight: 352.40.
(5R,6S)-6-[(1S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3-morpholinone is an active metabolite of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: 3-Morpholinone, 6-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-, (5R,6S)-; ent-Aprepitant-M3; Aprepitant M3 Metabolite (1S,5R,6S)-Isomer. Molecular formula: C20H16F7NO3. Mole weight: 451.33.
(5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-5-hydroxy-3-oxo-6-heptenoic Acid Sodium Salt
(5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-5-hydroxy-3-oxo-6-heptenoic Acid Sodium Salt is one of pitavastatin derivatives. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: sodium (S,E)-7-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-5-hydroxy-3-oxohept-6-enoate; sodium (E,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-5-hydroxy-3-oxo-hept-6-enoate. Molecular formula: C25H21FNNaO4. Mole weight: 441.43.
5-Triisopropylsilyl-ethynyl (S)-(-)-Nicotine
5-Triisopropylsilyl-ethynyl (S)-(-)-Nicotine is used to protect 5-Ethynyl Nicotine, an intermediate of the nicotinic acetylcholine receptor agonist SIB-1508Y. Synonyms: 3-[(2S)-1-Methyl-2-pyrrolidinyl]-5-[2-[tris(1-methylethyl)silyl]ethynyl]-pyridine; 3-[ (2S)-1-Methyl-2-pyrrolidinyl]-5-[ (triisopropylsilyl)ethynyl]pyridine; Pyridine, 3-[(2S)-1-methyl-2-pyrrolidinyl]-5-[2-[tris(1-methylethyl)silyl]ethynyl]-. Grades: ≥95%. CAS No. 916046-39-4. Molecular formula: C21H34N2Si. Mole weight: 342.59.
5-Vinyl-uridine
5-Vinyl-uridine is an innovative biomedical asset, exhibiting remarkable potential for research of diverse viral afflictions encompassing hepatitis C and influenza. Esteemed for its profound antiviral attributes, this formidable nucleoside analogue effectively hinders viral replication via intricate interference in theenhancement of viral RNA. Consequently, it successfully thwarts the exponential proliferation and dissemination of the virus throughout the entire physiological framework. Synonyms: 5-Ethenyl-uridine; 5-VU. Grades: ≥ 98% by HPLC. CAS No. 55520-64-4. Molecular formula: C11H14N2O6. Mole weight: 270.24.
6-(((1,3-Dioxolan-2-yl)methyl)amino)-1,3-dimethyl-5-nitropyrimidine-2,4(1H,3H)-dione is an intermediate in the synthesis of Doxofylline, which is a phosphodiesterase inhibitor and a xanthine derivative drug for asthma. Synonyms: 6-[(1,3-Dioxolan-2-ylmethyl)amino]-1,3-dimethyl-5-nitro-2,4(1H,3H)-pyrimidinedione; 2,4(1H,3H)-Pyrimidinedione, 6-[(1,3-dioxolan-2-ylmethyl)amino]-1,3-dimethyl-5-nitro-. Grades: 98%. Molecular formula: C10H14N4O6. Mole weight: 286.24.
6-(((1,3-Dioxolan-2-yl)methyl)amino)-5-amino-1,3-dimethylpyrimidine-2,4(1H,3H)-dione is an intermediate in the synthesis of Doxofylline, which is a phosphodiesterase inhibitor and a xanthine derivative drug for asthma. Synonyms: 6-[(1,3-Dioxolan-2-ylmethyl)amino]-5-amino-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione. Grades: 98%. Molecular formula: C10H16N4O4. Mole weight: 256.26.
6,21-Didehydro Prednisolone
6,21-Didehydro Prednisolone is an impurity of Prednisolone, which is a glucocorticoid and an anti-inflammatory drug used to treat central nervous system disorders. Synonyms: (11β)-11,17-Dihydroxy-3,20-dioxopregna-1,4,6-triene-21-al; Pregna-1,4,6-trien-21-al, 11,17-dihydroxy-3,20-dioxo-, (11β)-. Molecular formula: C21H24O5. Mole weight: 356.41.
One of the impurities of Tipiracil, which is a thymidine phosphorylase (TPase) inhibitor and has been found to be a potential drug candidate for metastatic colorectal cancer. Synonyms: Tipiracil Impurity des Cl. Grades: ≥95%. CAS No. 2069937-25-1. Molecular formula: C9H12N4O2. Mole weight: 208.22.
6-(3-((1r,3s,5R,7S)-3-Acetoxyadamantan-1-yl)-4-methoxyphenyl)-2-naphthoic Acid Ethyl Ester is an impurity of Adapalene, which is a third-generation topical retinoid primarily used in the treatment of mild-moderate acne. Synonyms: 2-Naphthalenecarboxylic acid, 6-[3-[(5R,7S)-3-(acetyloxy)tricyclo[3.3.1.13,7]dec-1-yl]-4-methoxyphenyl]-, ethyl ester. Molecular formula: C32H34O5. Mole weight: 498.61.
6-[(3-Adamantyl-4-methoxyphenyl)]-2-naphthoic Acid Ethyl Ester is an intermediate in the synthesis of Adapalene, which is a third-generation topical retinoid primarily used in the treatment of mild-moderate acne. Synonyms: 6-(4-Methoxy-3-tricyclo[3.3.1.13,7]dec-1-ylphenyl)-2-naphthalenecarboxylic Acid Ethyl Ester. Grades: ≥95%. CAS No. 951645-46-8. Molecular formula: C30H32O3. Mole weight: 440.57.
6-(4-Methoxyphenyl)-2-naphthoic Acid is a reactant in the synthesis of Adapalene, which is a third-generation topical retinoid primarily used in the treatment of mild-moderate acne. Synonyms: 2-(4-Methoxyphenyl)naphthalene-6-carboxylic Acid; 6-(4-Methoxyphenyl)-2-naphthalenecarboxylic Acid; 2-Naphthalenecarboxylic acid, 6-(4-methoxyphenyl)-. Grades: ≥95%. CAS No. 132292-17-2. Molecular formula: C18H14O3. Mole weight: 278.30.
6,7,8,8a-Tetrahydro-2H-naphtho[1,8-bc]furan-2-one is an intermediate in the synthesis of Palonosetron, which is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Synonyms: 2H-Naphtho[1,8-bc]furan-2-one, 6,7,8,8a-tetrahydro-. Grades: ≥95%. CAS No. 74145-12-3. Molecular formula: C11H10O2. Mole weight: 174.20.