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| Product | Description | |
|---|---|---|
| Everolimus EP Impurity B | An impurity of Everolimus, an mTOR blocker that inhibits the growth of certain cancer. Synonyms: Everolimus 19-Ene Open-Ring Impurity; Everolimus Related Compound 2; seco Everolimus; (19E/Z)-seco-[4-O-(2-Hydroxyethyl)] Rapamycin. CAS No. 1062122-63-7. Molecular formula: C53H83NO14. Mole weight: 958.22. |  |
| Everolimus EP Impurity C | An impurity of Everolimus, an mTOR blocker that inhibits the growth of certain cancer. Synonyms: (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18,19-trihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl]-30-methoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone; 19-O-demethyl everolimus. Molecular formula: C52H81NO14. Mole weight: 944.2. | |
| Everolimus EP Impurity D | An impurity of Everolimus, an mTOR blocker that inhibits the growth of certain cancer. Synonyms: (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1-hydroxy-18-(2-hydroxyethoxy)-12-[(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl]-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone; 18-O-hydroxyethyl sirolimus. Molecular formula: C53H83NO14. Mole weight: 958.22. | |
| Everolimus EP Impurity E | An impurity of Everolimus, an mTOR blocker that inhibits the growth of certain cancer. Synonyms: (1R,2R,4S)-4-[(2R)-2-[(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-2,3,10,14,20-pentaoxo-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraen-12-yl]propyl]-2-methoxycyclohexylformate. CAS No. 1237826-25-3. Molecular formula: C52H79NO14. Mole weight: 942.18. | |
| Everolimus EP Impurity F | An impurity of Everolimus, an mTOR blocker that inhibits the growth of certain cancer. Synonyms: (1R,9S,12S,15R,16E,18R,19S,20R,21R,23S,24S,25E,27Ξ,28E,30S,32S,35R)-27-ethoxy-1,18,20-trihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl]-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36,37-trioxa-4-azatetracyclo[30.3.1.120,24.04,9]heptatriaconta-16,25,28-triene-2,3,10,14-tetrone. Molecular formula: C55H89NO16. Mole weight: 1020.29. | |
| Everolimus Hydrolized Impurity | An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: seco Everolimus B; (2S)-1-[2-[(2R,3R,6S)-6-[(2S,3E,5E,7E,9S,11R,13R,14R,15E,17R,20S,21R)-14,20-Dihydroxy-22-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-2,13-dimethoxy-3,9,11,15,17,21-hexamethyl-12,18-dioxo-3,5,7,15-docosatetraen-1-yl]tetrahydro-. Grade: > 95%. CAS No. 769905-89-7. Molecular formula: C53H85NO15. Mole weight: 976.27. | |
| Everolimus Isomer C | An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: 9,14-Deepoxy-15-deoxo-14-deoxy-9,15-epoxy-15-hydroxy-42-O-(2-hydroxyethyl)-14-oxorapamycin. Grade: 80%. CAS No. 908340-97-6. Molecular formula: C53H83NO14. Mole weight: 958.25. | |
| Everolimus O-Desmethyl Impurity (Mixture of Diastereomers) | An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: 27-O-Desmethyl Everolimus. Grade: > 95%. Molecular formula: C52H81NO14. Mole weight: 944.22. | |
| Everolimus O-Ethyl Impurity | An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: 7-O-Desmethyl-7-O-ethyl Everolimus. Grade: > 95%. CAS No. 1704711-12-5. Molecular formula: C54H85NO14. Mole weight: 972.28. | |
| Everolimus O-Silyl Impurity | An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: 42-O-tert-Butyldimethylsilyloxyethyl Rapamycin; 42-O-[2-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]ethyl]rapamycin. Grade: > 95%. CAS No. 159351-68-5. Molecular formula: C59H97NO14Si. Mole weight: 1072.52. | |
| Everolimus Related Compound 1 | An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: O-Desmethyl Everolimus. Grade: > 95%. CAS No. 745779-75-3. Molecular formula: C52H81NO14. Mole weight: 944.22. | |
| Everolimus Related Compound 3 | Everolimus Ring-Opening Impurity. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: (2S)-1-[[(2R,3R,6S)-6-[(2S,3E,5E,7E,9S,11R)-2,13-Dimethoxy-3,9,11-trimethyl-12-oxo-3,5,7-tridecatrienyl]tetrahydro-2-hydroxy-3-methyl-2H-pyran-2-yl]oxoacetyl]-2-piperidinecarboxylic Acid. Grade: 95%. CAS No. 147438-30-0. Molecular formula: C32H49NO9. Mole weight: 591.75. | |
| Everolimus Related Compound 4 | An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: (2S)-1-[2-[(2R,3R,6S)-6-[(2S,3E,5E,7E,9S,11R,13R,14R,15E,17R,20S,21R)-14,20-Dihydroxy-22-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-2,13-dimethoxy-3,9,11,15,17,21-hexamethyl-12,18-dioxo-3,5,7,15-docosatetraen-1-yl]tetrahydro-2-hydroxy-3-methyl-. Grade: > 95%. Molecular formula: C57H91NO16. Mole weight: 1046.36. | |
| Everolimus Related Compound 5 | An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: Di-tert-butyl-4-methylene-2,5-cyclohexadienone; 2,6-Di-t-butyl-4-methylene-2,5-cyclohexadienone. Grade: > 95%. CAS No. 2607-52-5. Molecular formula: C15H22O. Mole weight: 218.34. | |
| Everolimus Ring-Opening Impurity | An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: Everolimus Retroaldol Degradation Product. Grade: 90% (Mixture of isomers). CAS No. 1708118-13-1. Molecular formula: C53H83NO14. Mole weight: 958.25. | |
| Evexomostat | Evexomostat is a methionine aminopeptidase 2 (MetAP2) inhibitor. Synonyms: poly({N-[(2RS)-2-hydroxypropyl]methacrylamide}-co-[N-methacryloylgly-cyl-L-phenylalanyl-L-leucyl-N1-(trans-4-{[({(3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl]-1-oxaspiro[2.5]-octan-6-yl}oxy)carbonyl]amino}cyclohexyl)glycinamide (~0.91:0.09 x)]); poly([N-(2-hydroxypropyl)methacrylamide]-co-{methacryloyl-Gly-Phe-Leu-Gly amide with O-[(trans-4-aminocyclohexyl)carbamoyl]fumagillol}). CAS No. 2416263-67-5. Molecular formula: [(C7H13NO2)n(C46H68N6O10)]m. | |
| Evifacotrep | Evifacotrep is a short transient receptor potential channel 5 (TRPC5) antagonist. Synonyms: 4-chloro-5-{4-[4-fluoro-2-(trifluoromethyl)phenoxy]-5,8-dihydropyrido[3,4-d]pyrimidin-7(6H)-yl}pyridazin-3(2H)-one. CAS No. 2413739-88-3. Molecular formula: C18H12ClF4N5O2. Mole weight: 441.77. | |
| Evinacumab | Evinacumab is a humanized anti-ANGPTL3 monoclonal antibody. Evinacumab has the potential therapeutic activity against homozygous familial hypercholesterolemia. Synonyms: Evkeeza; REGN1500. CAS No. 1446419-85-7. | |
| Evixapodlin | Evixapodlin is a human programmed cell death ligand 1 (PD-1/PD-L1) protein/protein interaction inhibitor with an IC50 of 0.213 nM. It has anticancer and antiviral functions. Synonyms: (12S,122S)-62,72-dichloro-53,86-dimethoxy-3,10-diaza-5,8(2,5)-dipyrazina-1,12(2)-dipyrrolidina-6,7(1,3)-dibenzenadodecaphane-15,125-dione; (5S,5'S)-5,5'-((((5,5'-(2,2'-dichloro-[1,1'-biphenyl]-3,3'-diyl)bis(3-methoxypyrazine-5,2-diyl))bis(methylene))bis(azanediyl))bis(methylene))bis(pyrrolidin-2-one); 2-Pyrrolidinone, 5,5'-[(2,2'-dichloro[1,1'-biphenyl]-3,3'-diyl)bis[(3-methoxy-5,2-pyrazinediyl)methyleneiminomethylene]]bis-, (5S,5'S)-; PD-1/PD-L1-IN 7. Grade: ≥98%. CAS No. 2374856-75-2. Molecular formula: C34H36Cl2N8O4. Mole weight: 691.61. | |
| Evocalcet | Evocalcet is a calcium-sensing receptor agonist under the development of Kyowa Hakko Kirin. Phase III clinical trials for Secondary hyperparathyroidism are on-going in Japan. Uses: Secondary hyperparathyroidism. Synonyms: MT-4580; MT 4580; MT4580; KHK-7580; KHK7580; KHK 7580; Evocalcet; 2-(4-((S)-3-(((R)-1-(naphthalen-1-yl)ethyl)amino)pyrrolidin-1-yl)phenyl)acetic acid. Grade: 98%. CAS No. 870964-67-3. Molecular formula: C24H26N2O2. Mole weight: 374.48. | |
| Evodenoson | Evodenoson is a selective A2A adenosine receptor agonist. Phase II clinical trials for the treatment of Glaucoma and Ocular hypertension were discontinued. Uses: Glaucoma;ocular hypertension. Synonyms: ATL313; ATL 313; ATL-313; DE-112; DE 112; DE112; methyl 4-[3-[6-amino-9-[(2R,3R,4S,5S)-5-(cyclopropylcarbamoyl)-3,4-dihydroxyoxolan-2-yl]purin-2-yl]prop-2-ynyl]piperidine-1-carboxylate. Grade: 98%. CAS No. 844873-47-8. Molecular formula: C23H29N7O6. Mole weight: 499.53. | |
| Evofosfamide | Evofosfamide is a hypoxia-activated prodrug consisting of a 2-nitroimidazole phosphoramidate conjugate with potential antineoplastic activity. The 2-nitroimidazole moiety of hypoxia-activated prodrug TH-302 acts as a hypoxic trigger, releasing the DNA-alkylating dibromo isophosphoramide mustard moiety within hypoxic regions of tumors. Normoxic tissues may be spared due to the hypoxia-specific activity of this agent, potentially reducing systemic toxicity. Synonyms: TH-302; TH 302; TH302; 2-bromo-N-[(2-bromoethylamino)-[(3-methyl-2-nitroimidazol-4-yl)methoxy]phosphoryl]ethanamine. Grade: > 98%. CAS No. 918633-87-1. Molecular formula: C9H16Br2N5O4P. Mole weight: 449.04. | |
| Evogliptin | This active molecular is a selective dipeptidyl peptidase 4 (DPP4) inhibitor under the development of Dong-A. Evogliptin improves insulin resistance and delays the onset of diabetes. Evogliptin monotherapy improved HbA1c, fasting plasma glucose level, OGTT results and β-cell function. In Sep 1st 2016, preclinical trials in Type-2 diabetes mellitus (Combination therapy) in Russia was on-going. In Sep 12th 2016, Phase-I clinical trials in non-alcoholic steatohepatitis (Combination therapy) in USA was on-going. Uses: Type-2 diabetes mellitus. Synonyms: (3R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-[(2-methylpropan-2-yl)oxymethyl]piperazin-2-one; CHEMBL1779710; UNII-09118300L7; DA-1229; DA 1229; DA1229; 1222102-29-5; Evogliptin [INN]; 1246960-27-9 (HCl). Grade: 98%. CAS No. 1222102-29-5. Molecular formula: C19H26F3N3O3. Mole weight: 401.43. | |
| Evogliptin hydrochloride | Evogliptin is a DPP-4 inhibitor, for the treatment of type 2 diabetes mellitus in patients with inadequately controlled by diet and exercise alone, or in combination with metformin when diet and exercise plus metformin alone do not provide satisfactory glycaemic control. CAS No. 1246960-27-9. Molecular formula: C19H27ClF3N3O3. Mole weight: 401.42. | |
| Evogliptin Tartrate | Evogliptin is an antidiabetic drug in the dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Synonyms: 2-Piperazinone, 4-[(3R)?-3-amino-1-oxo-4-(2,?4,?5-trifluorophenyl)?butyl]?-3-[(1,?1-dimethylethoxy)?methyl]?-, (3R)?-, (2R,?3R)?-2,?3-dihydroxybutanedioat?e (1:1). Grade: > 95%. CAS No. 1222102-51-3. Molecular formula: C19H26F3N3O3. C4H6O6. Mole weight: 401.43 150.09. | |
| Evogliptin Tartrate Impurity S1 | An isomer of Evogliptin. Evogliptin is an antidiabetic drug in the dipeptidyl peptidase-4 (DPP-6) inhibitor class of drugs. Synonyms: 2-Piperazinone, 4-[(3S)?-3-amino-1-oxo-4-(2,?4,?5-trifluorophenyl)?butyl]?-3-[(1,?1-dimethylethoxy)?methyl]?-, (3R)?-, (2R,?3R)?-2,?3-dihydroxybutanedioat?e (1:1). Grade: > 95%. Molecular formula: C19H26F3N3O3. C4H6O6. Mole weight: 401.43 150.09. | |
| Evogliptin Tartrate Impurity S2 | An isomer of Evogliptin. Evogliptin is an antidiabetic drug in the dipeptidyl peptidase-4 (DPP-5) inhibitor class of drugs. Synonyms: 2-Piperazinone, 4-[(3S)?-3-amino-1-oxo-4-(2,?4,?5-trifluorophenyl)?butyl]?-3-[(1,?1-dimethylethoxy)?methyl]?-, (3S)?-, (2R,?3R)?-2,?3-dihydroxybutanedioat?e (1:1). Grade: > 95%. Molecular formula: C19H26F3N3O3. C4H6O6. Mole weight: 401.43 150.09. | |
| Evogliptin Tartrate Impurity S3 | An isomer of Evogliptin. Evogliptin is an antidiabetic drug in the dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Synonyms: 2-Piperazinone, 4-[(3R)?-3-amino-1-oxo-4-(2,?4,?5-trifluorophenyl)?butyl]?-3-[(1,?1-dimethylethoxy)?methyl]?-, (3S)?-, (2R,?3R)?-2,?3-dihydroxybutanedioat?e (1:1). Grade: > 95%. Molecular formula: C19H26F3N3O3. C4H6O6. Mole weight: 401.43 150.09. | |
| Evolocumab | Evolocumab is a monoclonal antibody as well as an inhibitor of proprotein convertase subtilisin/kexin type 9 (PCSK9), a protein targeting LDL receptors. Inhibition of PCSK9 could prevent LDL receptors from degradation and promote the removal of LDL-C from blood circulation. Evolocumab is used for the treatment of hyperlipidemia. Uses: The treatment of hyperlipidemia. Synonyms: AMG 145; AMG-145; AMG145. CAS No. 1256937-27-5. Molecular formula: C6242H9648N1668O1996S56. Mole weight: 141800. | |
| Evomonoside | Evomonoside is a potent natural compound used for studying neurological diseases such as Alzheimer's and Parkinson's. Derived from natural sources, Evomonoside exhibits neuroprotective properties by preventing the formation of amyloid plaques in the brain. Synonyms: (3b,5b)-3-[(6-Deoxy-a-L-mannopyranosyl)oxy]-14-hydroxycard-20(22)-enolide; Digitoxigenin 3-rhamnoside; Digitoxigenin rhamnoside. CAS No. 508-93-0. Molecular formula: C29H44O8. Mole weight: 520.65. | |
| EVP-0015962 | EVP-0015962 is a selective Amyloid precursor protein secretase modulator under the development of FORUM Pharmaceuticals. Chronic treatment with EVP-0015962 can lower the production of Aβ42, attenuate memory deficits, and reduce Aβ plaque formation and inflammation in Tg2576 transgenic animals. EVP-0015962 shows a therapeutic alternative for disease modification in Alzheimer's disease. In Jun 2016, Phase-II for Alzheimer's disease in USA was discontinued. Uses: Alzheimer's disease. Synonyms: EVP-0015962; EVP 0015962; EVP0015962. SCHEMBL3660255; ZSERTYLZGRJLOO-UHFFFAOYSA-N; 2-(5-chloro-6-(2,2,2-trifluoroethoxy)-4'-(trifluoromethyl)biphenyl-3-yl)-3-cyclobutylpropanoic acid. Grade: 98%. CAS No. 1447811-26-8. Molecular formula: C22H19ClF6O3. Mole weight: 480.83. | |
| EVP-6124 | EVP-6124 is a novel partial agonist of α7 neuronal nicotinic acetylcholine receptors (nAChRs). It shows selectivity for α7 nAChRs and did not activate or inhibit heteromeric α4β2 nAChRs and improves memory performance by potentiating the acetylcholine response of α7 nicotinic acetylcholine receptors. Synonyms: EVP-6124; EVP6124; EVP 6124; MT-4666; MT4666; MT 4666; Encenicline. Grade: >98%. CAS No. 550999-75-2. Molecular formula: C16H17ClN2OS. Mole weight: 320.84. | |
| EW-7197 | EW-7197 is a potent and selective ALK5 inhibitor, displaying antimetastatic and anticancer effects. It inhibits TGF-β/Smad signaling, and abrogates TGF-β1-induced tumor cell migration and invasion. EW-7197 inhibits breast cancer metastasis to the lung. EW-7197 prolongs the life span of BALB/c 4T1 mice via inhibition of EMT. EW-7197 inhibits metastasis and enhances the activity of cytotoxic T lymphocytes (CTLs) in 4T1 orthotopic grafted mice. Synonyms: Vactosertib; N-(2-fluorophenyl)-5-(6-methyl-2-pyridinyl)-4-[1,2,4]triazolo[1,5-a]pyridin-6-yl-1H-imidazole-2-methanamine. Grade: >98%. CAS No. 1352608-82-2. Molecular formula: C22H18FN7. Mole weight: 399.433. | |
| EX1314 | BMS-604992 is a selective and orally active growth hormone secretagogue receptor (GHSR) agonist with high-affinity binding (Ki = 2.3 nM) and strong functional activity (EC50 = 0.4 nM). It stimulates feeding in rodents. Synonyms: BMS-604992; Carbamic acid, (2-amino-2-oxoethyl)methyl-, (3-((1S)-1-((2-amino-2-methyl-1-oxopropyl)amino)-2-(phenylmethoxy)ethyl)-1,2,4-triazolo(4,3-a)pyridin-5-yl)methyl ester, monohydrochloride; (3-{(1S)-2-(Benzyloxy)-1-[(2-methylalanyl)amino]ethyl}[1,2,4]triazolo[4,3-a]pyridin-5-yl)methyl (2-amino-2-oxoethyl)methylcarbamate hydrochloride (1:1). Grade: 98%. CAS No. 674343-47-6. Molecular formula: C24H32ClN7O5. Mole weight: 534.01. | |
| EX229 | EX229 (compound 991), also known as AMPK Activator 991, is a potent AMPK activator that displays 5-10-fold more potent than A769662 in activating AMPK. Synonyms: Compound 991; AMPK Activator 991; 5-[[6-chloro-5-(1-methylindol-5-yl)-1H-benzimidazol-2-yl]oxy]-2-methylbenzoic acid. Grade: ≥98%. CAS No. 1219739-36-2. Molecular formula: C24H18ClN3O3. Mole weight: 431.87. | |
| Ex 26 | Ex 26 is a potent and selective S1P1 receptor antagonist (IC50 = 0.93 nM) with > 3,000-fold selectivity over S1P2, S1P3, S1P4 and S1P5. It causes lymphocyte sequestration in peripheral lymph nodes, and upregulates S1P1 receptor expression. Synonyms: 1-[[[5'-[[1-(4-Chloro-3-methylphenyl)ethyl]amino]-2'-fluoro-3,5-dimethyl[1,1'-biphenyl]-4-yl]carbonyl]amino]-cyclopropanecarboxylic acid. Grade: ≥98% by HPLC. CAS No. 1233332-37-0. Molecular formula: C28H28ClFN2O3. Mole weight: 494.98. | |
| EX-527 | EX 527 is a potent and selective SIRT1 inhibitor with IC50 of 38 nM, exhibits >200-fold selectivity against SIRT2 and SIRT3. Synonyms: SEN0014196; EX-527; EX-527; EX-527; Selisistat. Grade: >98%. CAS No. 49843-98-3. Molecular formula: C13H13ClN2O. Mole weight: 248.71. | |
| EX-527 R-enantiomer | EX-527 R-enantiomer is the R-enantiomer of EX-527, which is a potent and selective SIRT1 inhibitor and with no inhibition on SIRT3 and SIRT3. It is a negative control of the active form EX-527 S-enantiomer. Synonyms: Selisistat R-enantiomer; (R)-Selisistat; EX-527(R); EX 527(R); EX527(R). Grade: >98%. CAS No. 848193-69-1. Molecular formula: C13H13ClN2O. Mole weight: 248.71. | |
| EX-527 S-enantiomer | EX-527 S-enantiomer is the S-enantiomer of EX-527, which is a potent and selective SIRT1 inhibitor and with no inhibition on SIRT3 and SIRT3. Synonyms: Selisistat S-enantiomer; EX-527(S); (S)-Selisistat; EX 527(S); EX527(S); EX-527S; EX527S. Grade: >98%. CAS No. 848193-68-0. Molecular formula: C13H13ClN2O. Mole weight: 248.71. | |
| Exalamide | Exalamide is a derivative of salicylamide used as an antifungal. Uses: Used as an antifungal. Synonyms: 2-(Hexyloxy)benzamide; 2-hexoxybenzamide. Grade: ≥95%. CAS No. 53370-90-4. Molecular formula: C13H19NO2. Mole weight: 221.3. | |
| Exatecan mesilate hydrate | Exatecan mesylate inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA and inhibiting religation of DNA breaks, thereby inhibiting DNA replication and triggering apoptotic cell death. Synonyms: Exatecan methanesulfonate dihydrate; DX 8951 mesilate hydrate. CAS No. 197720-53-9. Molecular formula: C25H30FN3O9S. Mole weight: 567.58. | |
| Exbivirumab | Exbivirumab is a human monoclonal antibody that targets hepatitis B surface antigen. Exbivirumab has the potential for the treatment of hepatitis B infections. Grade: 95%. CAS No. 569658-80-6. Molecular formula: C15H11BrClNO2S. Mole weight: 384.7. | |
| Exemestane-d3 | One of the isotopic labelled form of Exemestane, which is a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6-Methyleneandrosta-1,4-diene-3,17-dione-d3. Molecular formula: C20H21O2D3. Mole weight: 299.43. | |
| Exemestane-d5 | One of the isotopic labelled form of Exemestane, which is a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6-Methyleneandrosta-1,4-diene-3,17-dione-d5. Molecular formula: C20H19O2D5. Mole weight: 301.44. | |
| Exemestane Impurity 1 | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 1,2-α-Epoxy Exemestane; (1α,2α)-1,2-Epoxy-6-methyleneandrost-4-ene-3,17-dione. Grade: > 95%. CAS No. 159354-61-7. Molecular formula: C20H24O3. Mole weight: 312.41. | |
| Exemestane Impurity 3 | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6,16-Dimethylideneandrosta-1,4-diene-3,17-dione. Grade: > 95%. Molecular formula: C21H24O2. Mole weight: 308.42. | |
| Exemestane Impurity 4 | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 16-methylideneandrosta-1,4-diene-3,17-dione. Grade: > 95%. Molecular formula: C20H24O2. Mole weight: 296.41. | |
| Exemestane Metabolite 1 | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 17β-Hydroxy Exemestane Sulfamate; (17β)-17-[(Aminosulfonyl)oxy]-6-methyleneandrosta-1,4-dien-3-one. Grade: > 95%. Molecular formula: C20H27NO4S. Mole weight: 377.51. | |
| Exemestane Metabolite 2 | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6-Hydroxy-6-(methoxymethyl)-androsta-1,4-diene-3,17-dione. Grade: > 95%. Molecular formula: C21H28O4. Mole weight: 344.45. | |
| Exemestane Related Compound | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6α-(Methoxymethyl)androsta-1,4-dien-3,17-dione. Grade: > 95%. CAS No. 881896-95-3. Molecular formula: C21H28O3. Mole weight: 328.46. | |
| Exemestane Related Compound 1 | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6β-(Formyl)androsta-1,4-dien-3,17-dione. Grade: > 95%. Molecular formula: C20H24O3. Mole weight: 312.41. | |
| Exemestane Related Compound 2 | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 17-hydroxy-8,10,13-trimethyl-3-oxo--decahydro-3H-cyclopenta[a]phenanthrene-6-carboxylic acid. Grade: > 95%. Molecular formula: C20H24O3. Mole weight: 312.41. | |
| Exemestane Related Compound 2 (17-alpha isomer) | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 17-alpha-hydroxy-8,10,13-trimethyl-3-oxo--decahydro-3H-cyclopenta[a]phenanthrene-6-carboxylic acid. Grade: > 95%. Molecular formula: C20H24O3. Mole weight: 312.41. | |
| Exemestane Related Compound 2 (17-beta isomer) | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 17-beta-hydroxy-8,10,13-trimethyl-3-oxo--decahydro-3H-cyclopenta[a]phenanthrene-6-carboxylic acid. Grade: > 95%. Molecular formula: C20H24O3. Mole weight: 312.41. | |
| Exemestane Related Compound A | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 1,2-Dihydro Exemestane; 6-Methyleneandrost-4-ene-3,17-dione; 6-Methyleneandrost-4-en-3,17-dione. Grade: > 95%. CAS No. 19457-55-7. Molecular formula: C20H26O2. Mole weight: 298.43. | |
| Exemestane Related Compound B | Isotope labelled Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: Androsta-1,4-diene-3,17-dione, 6-(hydroxymethyl). Grade: > 95%. CAS No. 184972-09-6. Molecular formula: C20H26O3. Mole weight: 314.43. | |
| Exeporfinium chloride | Exepor?nium is an anti-microbial that works via weakening bacteria cell walls. It can be used for the treatment for MRSA (methicillin-resistant Staphylococcus aureus) and possibly Clostridium difficile. In Apr 2016, Destiny Pharma completed a phase I/II trial in Staphylococcal infections in USA. Uses: Staphylococcal infections. Synonyms: XF73; XF 73; XF-73; 3,3'-((porphyrin-5,15-diylbis(4,1-phenylene))bis(oxy))bis(N,N,N-trimethylpropan-1-aminium) chloride; 756818-36-7 (XF-73 Free). Grade: 98%. CAS No. 718638-68-7. Molecular formula: C44H50Cl2N6O2. Mole weight: 765.82. | |
| Exifone | Exifone, a nonessential HDAC1 activator, is a nootropic drug and cognitive enhancing agent used in Alzheimer's disease and Parkinson's disease. Synonyms: 2,3,3',4,4',5'-Hexahydroxybenzophenone; 2,3,4,3',4',5'-Hexahydroxybenzophenone; 3,4,5,2',3',4'-Hexahydroxybenzophenone; 4-Galloylpyrogallol; Adlone; NSC 680919; Methanone, (2,3,4-trihydroxyphenyl)(3,4,5-trihydroxyphenyl)-. Grade: 95%. CAS No. 52479-85-3. Molecular formula: C13H10O7. Mole weight: 278.21. | |
| Exisulind | An active metabolite of Sulindac. Exisulind induces apoptosis through the activation of protein kinase G (PKG). Uses: Anticarcinogenic agents. Synonyms: Sulindac sulfone; Aptosyn; Prevatec; FGN-1; cis-5-Fluoro-2-methyl-1-(p-methylsulfonylbenzylidenyl)indene-3-acetic acid; (Z)-2-(5-fluoro-2-methyl-1-(4-(methylsulfonyl)benzylidene)-1H-inden-3-yl)acetic acid. CAS No. 59973-80-7. Molecular formula: C20H17FO4S. Mole weight: 372.41. | |
| EXO1 | Exo1 is a cell-permeable and reversible inhibitor of exocytosis (IC50 = 20 μM). Exo1 is a reversible inhibitor of vesicular trafficking between the endoplasmic reticulum and the Golgi apparatus. Exo1 releases ADP-ribosylation factor (ARF)1 from Golgi and disrupts the functions of Golgi. Synonyms: Benzoic acid, 2-[(4-fluorobenzoyl)amino]-, methyl ester; Methyl 2-[(4-fluorobenzoyl)amino]benzoate; 2-(4-Fluoro-benzoylamino)-benzoic acid methyl ester; NSC 214045; Exo1. Grade: 98%. CAS No. 75541-83-2. Molecular formula: C15H12FNO3. Mole weight: 273.26. | |
| exo-Hydroxytandospirone-d8 | An isotope labelled derivative of Tandospirone. Tandospirone is an anxiolytic and antidepressant drug which belongs to azapirone class. Grade: 95% by HPLC; 98% atom D. Molecular formula: C21H21D8N5O3. Mole weight: 407.54. | |
| exo-IWR 1 | exo-IWR 1, the enantiomer of IWR-1 and the diastereomer of IWR-1-endo, is a potent SAR anticancer Wnt response inhibitor, which is a kind of small secreted proteins and are active in tissue homeostasis, tumorigenesis and embryonic development. It shows decreased activity against the Wnt/β-catenin pathway. It may be an ideal control for tests involving the active form, IWR-1-endo. It may be used in the treatment of some diseases and conditions such as degenerative diseases, cancers, osteopetrosis and type II diabetes. Synonyms: rel-4-[(3aR,4R,7S,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide; 4-[(3aR,4R,7S,7aS-rel)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide. Grade: ≥99% by HPLC. CAS No. 1127442-87-8. Molecular formula: C25H19N3O3. Mole weight: 409.44. | |
| exo-Tropine-3-thiol Hydrochloride | exo-Tropine-3-thiol Hydrochloride is used in the synthesis of Retapamulin, which is a topical antibiotic used for the topical treatment of impetigo caused by Staphylococcus aureus (methicillin-susceptible only) or Streptococcus pyogenes. Synonyms: 8-Azabicyclo[3.2.1]octane-3-thiol, 8-methyl-, hydrochloride (1:1), (3-exo)-; (3-exo)-8-Methyl-8-azabicyclo[3.2.1]octane-3-thiol hydrochloride (1:1). CAS No. 1141886-66-9. Molecular formula: C8H15NS.HCl. Mole weight: 193.74. | |
| Eyeliss | Eyeliss is a cosmetic indegredient that has been used to relieve puffiness under eye bags and reduce dark circles beneath the eyes. Grade: 98%. | |
| Ezatiostat hydroChloride | Ezatiostat hydrochloride is the hydrochloride salt form of Ezatiostat. Ezatiostat, also called as Telintra or TER 199, is a liposomal small-molecule glutathione analog inhibitor of glutathione S-transferase (GST) P1-1 with hematopoiesis-stimulating activi. Synonyms: ethyl (2S)-2-amino-5-[[(2R)-3-benzylsulfanyl-1-[[(1R)-2-ethoxy-2-oxo-1-phenylethyl]amino]-1-oxopropan-2-yl]amino]-5-oxopentanoate; hydrochloride ezatiotsat gamma-Glu-S-BzCys-PhGly diethyl ester gamma-glutamyl-S-(benzyl)cysteinyl-phenylglycine diethyl ester. CAS No. 286942-97-0. Molecular formula: C27H35N3O6S.HCl. Mole weight: 566.11. | |
| Ezatiostat TFA | Ezatiostat is a glutathione analog that acts as an inhibitor of glutathione S-transferase (GST) P1-1. TLK117, the active form of ezatiostat, inhibits GSTP1-1, resulting in phosphorylation of JNK, restoring JNK-mediated cellular proliferation and differentiation signaling pathways. Synonyms: Telintra TFA; TLK-199 TFA; TLK 199 TFA. Molecular formula: C27H35N3O6S. Mole weight: 529.65. | |
| Ezeprogind disulfate | Ezeprogind disulfate is an orally active neurotrophic inducer. Ezeprogind disulfate is a potent neuroprotectant and can be used for the research of neurological disorders, including progressive supranuclear palsy (PSP), tauopathies, Alzheimer's and Parkinson's diseases, et al. Synonyms: AZP-2006 disulfate; N-(3-(4-(3-(Diisobutylamino)propyl)piperazin-1-yl)propyl)-1H-benzo(d)imidazol-2-amine disulphate salt. Grade: 99%. CAS No. 1616671-13-6. Molecular formula: C25H48N6O8S2. Mole weight: 624.81. | |
| Ezetimibe 2-Fluoro Impurity | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L26) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4R)-1-(2-fluorophenyl)-3-(3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one. Grade: > 95%. Molecular formula: C24H21F2NO3. Mole weight: 409.44. | |
| Ezetimibe 3-Fluoro Impurity | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L27) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: Ezetimibe m-Fluoroaniline analog; (3R,4S)-1-(3-Fluorophenyl)-3-[(S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one; N-Des(4-Fluorophenyl)-N-(3-fluorophenyl) Ezetimibe; (3R,4S)-1-(3-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone; m-Fluoroaniline isomer of Ezetimibe; 3-Fluoro Ezetimibe. Grade: >95%. CAS No. 1700622-06-5. Molecular formula: C24H21F2NO3. Mole weight: 409.44. | |
| Ezetimibe Aniline Impurity | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L28) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: 4-Dehydroxy-4-amino Ezetimibe; (3R,4S)-4-(4-Aminophenyl)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-2-azetidinone. Grade: > 95%. CAS No. 1354716-98-5. Molecular formula: C24H22F2N2O2. Mole weight: 408.45. | |
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