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α-Cyclogeranonitrile
α-Cyclogeranonitrile is used in the synthesis of Retinoic acid derivatives. Synonyms: 2,6,6-Trimethyl-2-cyclohexene-1-carbonitrile; 2-Cyclohexene-1-carbonitrile, 2,6,6-trimethyl-; 2,6,6-Trimethylcyclohex-2-ene-1-ylcarbonitrile. Grades: ≥95%. CAS No. 57524-13-7. Molecular formula: C10H15N. Mole weight: 149.23.
(+)-α-Dihydrotetrabenazine
(+)-α-Dihydrotetrabenazine is an impurity of Tetrabenazine, which is a VMAT-2 inhibitor and has been found to be effective in the treatment of hyperkinetic movement disorder at some extent. Synonyms: [2R-(2α,3β,11bβ)]-1,3,4,6,7,11b-Hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-ol; (+)-(2R,3R,11bR)-Dihydrotetrabenazine; (+)-DTBZ; (+)-Dihydrotetrabenazine; (2R,3R,11bR)-DHTBZ; Tetrabenazine Related Impurity 27(2R,3R,11bR); (+-)-3c-Isobutyl-9,10-dimethoxy-(11br)-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isochinolin-2t-ol; trans-2 hydroxy-3 isobutyl-9,10 dimethoxy-1,2,3,4,6,7 hexahydro-11bH-benzo(a)quinolizine; 2H-Benzo[a]quinolizin-2-ol,1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-,(2R,3R,11bR); dihydrotetrabenazine, (2alpha, 3beta, 11bbeta)-isomer; TBZOH cpd. Grades: ≥ 95%. CAS No. 85081-18-1. Molecular formula: C19H29NO3. Mole weight: 319.44.
α-epidermal growth factor, human
Recombinant human epidermal growth factor has the same structure as the human epidermal growth factor. EGF binds to epidermal growth factor receptor (EGFR) and stimulates cell growth and proliferation. Recombinant human epidermal growth factor is approved for the treatment of diabetic foot ulcers. Uses: The treatment of diabetic foot ulcers. Synonyms: Human EGF; Nepidermin. CAS No. 62253-63-8. Molecular formula: C270H401N73O83S7. Mole weight: 6222.
α-Hydroxy-4-phenoxybenzeneacetonitrile
α-Hydroxy-4-phenoxybenzeneacetonitrile is an intermediate in the synthesis of para-Cypermethrin, which is a synthetic pyrethroid insecticide used on cotton trees, fruit trees and vegetables. Synonyms: Hydroxy-(4-phenoxy-phenyl)-acetonitrile. Grades: 98%. CAS No. 177793-92-9. Molecular formula: C14H11NO2. Mole weight: 225.24.
One of the impurities of Voriconazole, which has been found to be an ergosterol biosynthesis inhibitor and could be used as an antifungal agent. Synonyms: Voriconazole (2R,3R)-Isomer; Voriconazole 3-Epimer; (2R,3R)-3-(6-chloro-5-fluoropyrimidin-4-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol compound with (2S,3S); Voriconazole Impurity 12. CAS No. 137234-76-5. Molecular formula: C16H13ClF3N5O. Mole weight: 383.76.
(αR,βS)-β-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-hydroxy-4-(phenylmethoxy)-benzenepropanoic Acid Ethyl Ester is used in the synthesis of Paclitaxel, which is a chemotherapy medication used to treat a number of types of cancer. Uses: Used in the synthesis of paclitaxel metabolite. Synonyms: tert-butyl ((1S,2R)-1-(4-(benzyloxy)phenyl)-2-hydroxy-3-oxohexyl)carbamate; Paclitaxel Impurity 100; Ethyl (2R, 3S) -3-[4- (benzyloxy) phenyl]-2-hydroxy-3- ({[ (2-methyl-2-propanyl) oxy]carbonyl}amino) propanoate; Benzenepropanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-4-(phenylmethoxy)-, ethyl ester, (αR,βS)-. Grades: ≥95%. CAS No. 382596-26-1. Molecular formula: C23H29NO6. Mole weight: 415.48.
α-Tocopherol Phosphate Disodium Salt
α-Tocopherol phosphate, together with α-tocopherol acetate, α-tocopherol-nicotinate, α-tocopherol succinate and other esterified forms, has similar but different activities as vitamin E supplements. Synonyms: [2R-[2R*(4R*,8R*)]]-3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-Benzopyran-6-ol Dihydrogen Phosphate Disodium Salt; Disodium α-tocopheryl Phosphate; sodium 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)chroman-6-yl phosphate. Grades: >98%. CAS No. 90940-45-7. Molecular formula: C29H49O5PNa2. Mole weight: 554.65.
(Arg)9
(Arg)9, also known as Nona-L-arginine or Peptide R9, is a cell-permeable peptide used for drug delivery with neuroprotective activity (IC50= 0.78 μM in the glutamic acid model). Synonyms: Nona-L-arginine; Peptide R9. Grades: 98%. CAS No. 143413-47-2. Molecular formula: C54H110N36O10. Mole weight: 1423.69.
Bacampicillin Hydrochloride
Bacampicillin is a prodrug of ampicillin, a broad-spectrum aminopenicillin antibiotic with bactericidal activity. Uses: A prodrug of ampicillin with improved oral bioavailability. Synonyms: (2S,5R,6R)-6-[[(2R)-2-Amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid 1-[(Ethoxycarbonyl)oxy]ethyl Ester Hydrochloride; Penglobe; Spectrobid; Bacampicine; Ambacamp; Ambaxin; Bacacil; [2S-[2α,5α,6β(S*)]]-6-[(Aminophenylacetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid 1-[(Ethoxycarbonyl)oxy]ethyl Ester Hydrochloride; Pengood; ambaxin; BACAMPICILLIN HYDROCHLORIDE; Bacampicillin HCl. Grades: ≥95%. CAS No. 37661-08-8. Molecular formula: C21H28ClN3O7S. Mole weight: 501.98.
Bacitracin Zinc
Bacitracin Zinc is a dephosphorylation of the C55-isoprenyl pyrophosphate interference for inhibition of cleavage of Tyr from Met-enkephalin with IC50 of 10 μM. It can be used to promote the growth of cattle, pigs and poultry. Grades: >98%. CAS No. 1405-89-6. Molecular formula: C66H101N17O16SZn. Mole weight: 1486.07.
Baclofen Lactose Adduct
Baclofen Lactose Adduct is a lactose adduct of Baclofen, which is a specific GABA-B receptor agonist with muscle relaxant effect. Synonyms: N-[3-Carboxy-2-(4-chlorophenyl)propyl]-4-O-β-D-galactopyranosyl-D-glucopyranosylamine; D-Glucopyranosylamine, N-[3-carboxy-2-(4-chlorophenyl)propyl]-4-O-β-D-galactopyranosyl-. Molecular formula: C22H32ClNO12. Mole weight: 537.94.
BAM 15
BAM 15 is a novel mitochondrial protonophore uncoupler that uncouples oxidative phosphorylation in L6 myoblast mitochondria in vitro (EC50 = 270 nM). BAM 15 cannot depolarize the plasma membrane, and protects mice from acute renal ischemic-reperfusion injury. BAM 15 has the potential to treat obesity, Parkinson's disease, and aging. Synonyms: BAM15; BAM-15; N5,N6-bis(2-Fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine; N-[6-(2-Fluoroanilino)[1,2,5]oxadiazolo[3,4-b]pyrazin-5-yl]-N-(2-fluorophenyl)amine. Grades: ≥98% by HPLC. CAS No. 210302-17-3. Molecular formula: C16H10F2N6O. Mole weight: 340.29.
BAR-501
BAR-501, a UDCA derivative, is a selective GPBAR1 agonist devoid of any FXR agonistic activity. BAR-501 effectively transactivates GPBAR1 in HEK293 cells overexpressing a CRE along with GPBAR1, with a EC50 of 1 μM. Besides, it protects against development of portal hypertension in rodent models of liver injury and endothelial dysfunction. Synonyms: 3R,5S,6S,7S,8S,9S,10S,13R,14S,17R)-6-ethyl-17-((R)-5-hydroxypentan-2-yl)-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol; BAR-501; BAR 501; BAR501. CAS No. 1632118-69-4. Molecular formula: C26H46O3. Mole weight: 406.651.
Basmisanil
Basmisanil is a highly selective inverse agonist/negative allosteric modulator GABAAα5 receptors. It was developed by Roche to treat cognitive impairment associated with Down syndrome. In Apr 2016, Roche completed the phase II in Down syndrome (In adolescents, In adults) in USA, Argentina, Canada, France, Italy, Mexico, New Zealand, Singapore, Spain and the UK. In Sep 2016, Phase-II clinical trials in Neurological disorders (In adults, In the elderly) in Spain was on going. Uses: Down syndrome; neurological disorders. Synonyms: (1,1-dioxidothiomorpholino)(6-((3-(4-fluorophenyl)-5-methylisoxazol-4-yl)methoxy)pyridin-3-yl)methanone; RG 1662; RG-1662; RG1662; RO5186582; RO-5186582; RO 5186582. Grades: 98%. CAS No. 1159600-41-5. Molecular formula: C21H20FN3O5S. Mole weight: 445.47.
Batabulin sodium
Batabulin sodium is a synthetic pentafluorophenylsulfonamide with potential antineoplastic activity. T138067 covalently binds to and selectively modifies the beta 1, beta 2, beta 3, and beta 4 isotypes of beta tubulin at a conserved cysteine residue, resulting in disruption of microtubule polymerization, collapse of the cytoskeleton. Synonyms: T138067 sodium; T138067-sodium; T 138067 sodium; T 67; D03059; D 03059; D-03059; T-138067 sodium. CAS No. 195533-53-0. Molecular formula: C13H7F6NO3S. Mole weight: 371.253.
Batefenterol
Batefenterol is a Beta 2 adrenergic receptor agonist and also a Muscarinic receptor antagonist. It shows high affinity for hM2 (Ki = 1.4 nM), hM3 muscarinic receptors (Ki = 1.3 nM) and hβ2-adrenoceptors (Ki = 3.7 nM). Batefenterol is a hβ2-adrenoceptor agonist with EC50 value of 0.29 nM for stimulation of cAMP levels. This is 440- and 320-fold functional selectivity over hβ1- and hβ3-adrenoceptors. In Jul 2016, GlaxoSmithKline completed a phase II trial for Chronic obstructive pulmonary disease in USA, Germany and South Africa. Uses: Chronic obstructive pulmonary disease. Synonyms: GSK-961081; TD-5959; GSK 961081; TD 5959; GSK961081; TD5959; (R)-1-(3-((2-chloro-4-(((2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethyl)amino)methyl)-5-methoxyphenyl)amino)-3-oxopropyl)piperidin-4-yl [1,1'-biphenyl]-2-ylcarbamate. Grades: 98%. CAS No. 743461-65-6. Molecular formula: C40H42ClN5O7. Mole weight: 740.25.
Batefenterol Succinate
Batefenterol is a beta 2 adrenergic receptor agonist and also a muscarinic receptor antagonist. It shows high affinity for hM2 (Ki = 1.4 nM), hM3 muscarinic receptors (Ki = 1.3 nM) and hβ2-adrenoceptors (Ki = 3.7 nM). Batefenterol is a hβ2-adrenoceptor agonist with EC50 value of 0.29 nM for stimulation of cAMP levels. This is 440- and 320-fold functional selectivity over hβ1- and hβ3-adrenoceptors. Synonyms: Batefenterol Succinate; 945905-37-3; UNII-552KVF22JT; Batefenterol succinate [USAN]552KVF22JT. CAS No. 945905-37-3. Molecular formula: C44H48ClN5O11. Mole weight: 858.3.
Batimastat
Batimastat (also known as BB-94) is a synthetic matrix metalloproteinase inhibitor that has shown antineoplastic and antiangiogenic activity in various tumor models. Batimastat acts as an inhibitor of metalloproteinase activity by binding the zinc ion in the active site of MMPs. Uses: Antineoplastic agents. Synonyms: (2S,3R)-N-Hydroxy-N'-[(2S)-1-methylamino-1-oxo-3-phenylpropan-2-yl]-3-(2-methylpropyl)-2-(thiophen-2-ylsulfanylmethyl)butanediamide; BB94; BB-94; BB 94. Grades: 98%. CAS No. 130370-60-4. Molecular formula: C23H31N3O4S2. Mole weight: 477.638.
BAY-1895344
BAY-1895344 is a selective ATR (ataxia-telangiectasia and Rad3 related protein) inhibitor that inhibits proliferation of a broad spectrum of human tumor cell lines (median IC50 = 78 nM). BAY-1895344 is developed for the treatment of patients with advanced solid tumors and lymphomas, and it is undergoing a phase I clinical trial of safety and tolerability for cancer patients. Uses: A selective atr (ataxia-telangiectasia and rad3 related protein) inhibitor used for the treatment of advanced solid tumors and lymphomas. Synonyms: BAY-1895344; BAY 1895344; BAY1895344; (R)-3-methyl-4-(4-(1-methyl-1H-pyrazol-5-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl)morpholine. Grades: ≥98 %. CAS No. 1876467-74-1. Molecular formula: C20H21N7O. Mole weight: 375.181.
BAY 299
BAY 299 is a potent and selective inhibitor of BRD1 and TAF1 (IC50 = 6-67 and 8-13 nM, respectively) with selectivity over other bromodomains (>30-fold over other members of the BRPF family; BRD9 and ATAD2; >300-fold over BRD4). BAY 299 suppresses binding of BRD1 and TAF1 to histone H4 (IC50 = 575 nM and 0.9 μM, respectively) and histone H3.3 (IC50 = 825 nM and 1.4 μM, respectively). Synonyms: BAY-299; BAY 299; BAY299. 6-(3-Hydroxypropyl)-2-(1,3,6-trimethyl-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)-1H-benzo[de]isoquinoline-1,3(2H)-dione. Grades: ≥98% by HPLC. CAS No. 2080306-23-4. Molecular formula: C25H23N3O4. Mole weight: 429.47.
BAY 41-4109
BAY 41-4109 is a novel drug inhibiting hepatitis B virus capsid formation and replication. Synonyms: BAY-41-4109; BAY41-4109; BAY 41-4109; BAY-414109; BAY414109; BAY 414109. methyl (4R)-4-(2-chloro-4-fluorophenyl)-2-(3,5-difluoropyridin-2-yl)-6-methyl-1,4-dihydropyrimidine-5-carboxylate. Grades: >98%. CAS No. 298708-81-3. Molecular formula: C18H13ClF3N3O2. Mole weight: 395.766.
BAY-57-1293
BAY 57-1293 represents a new class of potent inhibitors of herpes simplex virus (HSV) that target the virus helicase primase complex. Potent helicase-primase inhibitor (HPI) effective against herpes simplex virus (HSV) infections with IC50 value of 20 nM for inhibition of the replication of both HSV-1 and HSV-2 in Vero cells, and ED50 value of 0.5 mg/kg for both HSV-1 and HSV-2 in the murine lethal challenge model of disseminated herpes. Uses: For research used only. Synonyms: Pritelivir; BAY-57-1293; BAY 57-1293; BAY-57 1293; BAY 57 1293; BAY571293; AIC316; AIC 316; AIC-316. Grades: 98%. CAS No. 348086-71-5. Molecular formula: C18H18N4O3S2. Mole weight: 402.49.
BAY-876
BAY-876 is a potent and selective inhibitor of GLUT1, which is overexpressed in multiple cancers. Uses: Anticancer agent. Synonyms: BAY-876; BAY 876; BAY876. 4-N-[1-[(4-cyanophenyl)methyl]-5-methyl-3-(trifluoromethyl)pyrazol-4-yl]-7-fluoroquinoline-2,4-dicarboxamide. Grades: 95%. CAS No. 1799753-84-6. Molecular formula: C24H16F4N6O2. Mole weight: 496.426.
(±)-Bay K 8644
(±)-Bay K 8644 is a L-type Ca2+ channel activator. It exhibits positive inotropic, vasoconstrictive and behavioral effects in vivo. Uses: Reprogramming. Synonyms: Bay K 8644; (+/-)-BAY K 8644; BAY-K-8644; methyl 2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylate. Grades: 98%. CAS No. 71145-03-4. Molecular formula: C16H15F3N2O4. Mole weight: 356.3.
BDA-366
BDA-366 is a small-molecule antagonist of Bcl2-BH4 domain with high affinity and selectivity for Bcl2-BH4. BDA-366 induces apoptosis in multiple myeloma cells via Bcl2 conformational change. Synonyms: BDA-366; BDA 366; BDA366; 1-[[(2S)-3-(diethylamino)-2-hydroxypropyl]amino]-4-[[(2S)-oxiran-2-yl]methylamino]anthracene-9,10-dione. Grades: >98%. CAS No. 1909226-00-1. Molecular formula: C24H29N3O4. Mole weight: 423.513.
BEC HCl
BEC HCl is an Arginase II inhibitor(Ki=0.31μM).In vitro,BEC HCl enhances NO-dependent smooth muscle relaxation by binding to arginase as a transition state analogue.In vivo,BEC HCl enhances peribronchiolar and perivascular inflammation in mice. Synonyms: (2R)-2-amino-3-(2-boronoethylsulfanyl)propanoic acid hydrochloride. Grades: 98%. CAS No. 222638-67-7. Molecular formula: C5H13BClNO4S. Mole weight: 229.482.
Bedaquiline
TMC207 is a first-in-class diarylquinoline compound with a novel mechanism of action, the inhibition of bacterial ATP synthase, and potent activity against drug-sensitive and drug-resistant TB. Synonyms: Sirturo; TMC207; TMC-207; TMC 207; R207910; R-207910; R 207910. Grades: 98%. CAS No. 843663-66-1. Molecular formula: C32H31BrN2O2. Mole weight: 555.5.
Bedaquiline fumarate
Bedaquiline fumarate is an anti-tuberculosis drug which selectively inhibits the mycobacterial energy metabolism and found to be effective against all states of Mycobacterium tuberculosis. It possesses a unique mechanism of action that disrupts the activity of the mycobacterial adenosine triphosphate synthase. It has an excellent in vitro activity against Mycobacterium tuberculosis, including multidrug resistant M tuberculosis, however, its side effect profile limits its use against MDR-TB when no other effective regimen can be provided. Uses: Antitubercular agents. Synonyms: (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-naphthalen-1-yl-1-phenylbutan-2-ol fumarate. Grades: >98%. CAS No. 845533-86-0. Molecular formula: C36H35BrN2O6. Mole weight: 671.58.
Bemcentinib
Bemcentinib is a selective small molecule inhibitor of Axl kinase, which showed activity to blocks tumor spread and prolongs survival in models of metastatic breast cancer. The receptor tyrosine kinase Axl may play an important role in cancer progression, invasion, metastasis, drug resistance, and patient mortality. R428 inhibits Axl with low nanomolar activity and blocked Axl-dependent events, including Akt phosphorylation, breast cancer cell invasion, and proinflammatory cytokine production. Pharmacologic investigations revealed favorable exposure after oral administration such that R428-treated tumors displayed a dose-dependent reduction in expression of the cytokine granulocyte macrophage colony-stimulating factor and the epithelial-mesenchymal transition transcriptional regulator Snail. In support of an earlier study, R428 inhibited angiogenesis in corneal micropocket and tumor models. R428 administration reduced metastatic burden and extended survival in MDA-MB-231 intracardiac and 4T1 orthotopic (median survival, >80 days compared with 52 days; P < 0.05) mouse models of breast cancer metastasis. Additionally, R428 synergized with cisplatin to enhance suppression of liver micrometastasis. Our results show that Axl signaling regulates breast cancer metastasis at multiple levels in tumor cells and tumor stromal cells and that selective Axl blockade confers therapeutic value in prolonging survival of animals bearing metastatic tumors. Synonyms: BGB324; BGB-324; BGB 324; R 428; R-428; R428; 1-(6,7-dihydro-5H-benzo[2,3]cyclohepta[2,4-d]pyridazin-3-yl)-3-N-[(7S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzo[7]annulen-3-yl]-1,2,4-triazole-3,5-diamine. CAS No. 1037624-75-1. Molecular formula: C30H34N8. Mole weight: 506.658.
Bendamustine Deschloro Dimer Impurity
Bendamustine Deschloro Dimer Impurity is an impurity of Bendamustine. Synonyms: 4-[5-((2-((4-(5-(Bis(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoyl)oxy)ethyl)(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanic Acid. Grades: > 95%. CAS No. 1391052-61-1. Molecular formula: C32H44N6O7. Mole weight: 624.74.
Bendamustine Desmethyl Impurity
Bendamustine Desmethyl Impurity is an impurity of Bendamustine, an anticancer drug used to treat chronic lymphocytic leukemia and non-Hodgkin's lymphoma. Synonyms: Bendamustine Desmethyl Impurity; Desmethyl Bendamustine Hydrochloride; 4-[6-[Bis(2-chloroethyl)amino]-1H-benzimidazol-2-yl]butanoic acid; hydrochloride; FT-0696961. Grades: > 95%. CAS No. 31349-38-9. Molecular formula: C15H19Cl2N3O2. Mole weight: 344.24.
Bendamustine Dihydroxy Impurity
Bendamustine Dihydroxy Impurity is an impurity of Bendamustine. Synonyms: 5-[Bis(2-hydroxyethyl)aMino]-1-Methyl-1H-benziMidazole-2-butanoic Acid; Dihydroxy Bendamustine. Grades: > 95%. CAS No. 109882-30-6. Molecular formula: C16H23N3O4. Mole weight: 321.38.
Bendamustine Ether Impurity
Bendamustine Ether Impurity is an dimer impurity of Bendamustine. Synonyms: 4-(1-Methyl-5-morpholino-1H-benzo[d]imidazol-2-yl)butanoic Acid; 1-Methyl-5-(4-morpholinyl)-1H-benzimidazole-2-butanoic Acid. Grades: > 95%. CAS No. 1228552-02-0. Molecular formula: C16H21N3O3. Mole weight: 303.36.
Bendamustine Impurity A
Bendamustine Impurity A is an impurity of Bendamustine, a drug for treating formidable non-Hodgkin lymphoma and the enduring chronic lymphocytic leukemia. Synonyms: 5-[(2-Chloroethyl)(2-hydroxyethyl)aMino]-1-Methyl-1H-benziMidazole-2-butanoic Acid; Hydroxy BendaMustine. Grades: > 95%. CAS No. 109882-27-1. Molecular formula: C16H22ClN3O3. Mole weight: 339.83.
Bendamustine Impurity C
Bendamustine Impurity C is an impurity in commercial preparation of Bendamustine. Synonyms: Bendamustine Isopropyl Ester; 5-[Bis(2-chloroethyl)-amino]-1-methyl-1H-benzimidazole-2-butanoic Acid Isopropyl Ester; Isopropyl 4-(5-[Bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazol-2-yl) butanoate. Grades: > 95%. CAS No. 1313020-25-5. Molecular formula: C19H27Cl2N3O2. Mole weight: 400.35.
Bendamustine Impurity D
Bendamustine Impurity D is a degradation production of Bendamustine. Synonyms: 4-(6-(2-Chloroethyl)-3-methyl-3, 6, 7, 8-tetrahydroimidazo[4', 5':5, 6]benzo[1, 2-b][1, 4]thiazin-2-yl)butanoic Acid; 6-(2-Chloroethyl)-3,6,7,8-tetrahydro-3-methyl-Imidazo[4,5-h][1,4]benzothiazine-2-butanoic Acid; 4-(7,8-Dihydro-6-(2-Chloroethylamino)-3-methyl-1,4. Grades: > 95%. CAS No. 191939-34-1. Molecular formula: C16H20ClN3O2S. Mole weight: 353.87.
Bendamustine Related Impurity 1
Cas No. 3543-74-6.
Bendamustine Related Impurity 4
Bendamustine Related Impurity 4 is an impurity of bendamustine, a chemotherapy drug used for the therapy of non-Hodgkin lymphoma and chronic lymphocytic leukemia. Synonyms: N1-Methylbenzene-1,2,4-triaMine; 1,2,4-BenzenetriaMine, N1-Methyl-. Grades: > 95%. CAS No. 60651-29-8. Molecular formula: C7H11N3. Mole weight: 137.19.
Bendamustine Related Impurity 5
Bendamustine Related Impurity 5 is an impurity of bendamustine, a novel pharmaceuticals designed to treat chronic lymphocytic leukemia and non-Hodgkin lymphoma. Synonyms: 5-[(2-Chloroethyl)(2-hydroxyethyl)aMino]-1-Methyl-1H-benziMidazole-2-butanoic Acid Ethyl Ester. Grades: > 95%. CAS No. 898224-95-8. Molecular formula: C18H26ClN3O3. Mole weight: 367.88.
Benzamil
Benzamil is a Na+/Ca2+ exchanger (NCX) inhibitor and epithelial sodium channel (ENaC) blocker. Benzamil has been developed as a promising treatment for cystic fibrosis. Synonyms: Benzylamiloride. CAS No. 2898-76-2. Molecular formula: C13H14ClN7O. Mole weight: 319.75.
Benzamil hydrochloride
Benzamil hydrochloride is a Na+/Ca2+ exhanger (NCX) inhibitor (IC50 ~ 100 nM) and an epithelial sodium channel (ENaC) blocker. Benzamil is an analogue of amiloride, and it is potentially used for the treatment of cystic fibrosis. Uses: Potential treatment of cystic fibrosis. Synonyms: N-(Benzylamidino)-3,5-diamino-6-chloropyrazinecarboxamide hydrochloride. Grades: ≥98% by HPLC. CAS No. 161804-20-2. Molecular formula: C13H14ClN7O.HCl. Mole weight: 356.21.
Benzathine Benzylpenicillin EP Impurity A
Benzathine Benzylpenicillin EP Impurity A is an impurity of Benzylpenicillin, which is an antibiotic used to treat a number of bacterial infections. Uses: N-benzylethylenediamine can be used to develop imidazoline derivatives as ligands for dopamine d4 receptor. it is also a reagent for enantioselective synthesis of epoxides and piperazinones. Synonyms: N1-(Phenylmethyl)-1,2-ethanediamine; 1-Amino-2-(N-benzylamino)ethane; 2-(Benzylamino)ethylamine; N-(Phenylmethyl)-1,2-ethanediamine; N-Benzyl-1,2-diaminoethane; N-Benzyl-1,2-ethanediamine; N-Benzylethanediamine; NSC 18480. Grades: ≥95%. CAS No. 4152-9-4. Molecular formula: C9H14N2. Mole weight: 150.22.
Benzathine Diacetate
Benzathine is a diamine used as an ingredient in several drugs, including benzathine phenoxymethylpenicillin and benzathine benzylpenicillin. Synonyms: N,N'-Dibenzylethylenediamine diacetate; N1,N2-Dibenzylethane-1,2-diamine diacetate; 1,2-Di(benzylamino)ethane diacetate; Benzathine Diacetate Salt; DBED Diacetate Salt; N,N'-Bis(phenylmethyl)-1,2-ethanediamine Diacetate Salt; N,N'-Dibenzyl-1,2-diaminoethane Diacetate Salt. Grades: 98%. CAS No. 122-75-8. Molecular formula: C16H20N2.2(C2H4O2). Mole weight: 360.45.
Benzetimide hydrochloride is a muscarinic acetylcholine receptor antagonist that has anticholinergic properties and could block pilocarpine-induced lacrimation. Uses: Amuscarinic acetylcholine receptor antagonist. Synonyms: R 4929; R4929; R-4929Spasmentral;3-(1-benzylpiperidin-4-yl)-3-phenylpiperidine-2,6-dione;hydrochloride. Grades: ≥98%. CAS No. 5633-14-7. Molecular formula: C23H26N2O2.HCl. Mole weight: 398.93.
Benzo[d][1,3]dioxol-4-ol
An impurity of Paroxetine which is a selective serotonin reuptake inhibitor. Synonyms: 2H-1,3-Benzodioxol-4-ol; 2,3-Methylenedioxyphenol; 4-Hydroxy-1,3-benzodioxole;1,3-Benzodioxol-4-ol; Paroxetine Impurity 16. CAS No. 69393-72-2. Molecular formula: C7H6O3. Mole weight: 138.12.
Benzyl 3,5-bis(phenylmethoxy)benzoate
An impurity of Terbutaline, which is a β-Adrenergic receptor agonist and could be used as a bronchodilator agent. Synonyms: enzoic acid, 3,5-bis(phenylmethoxy)-, phenylmethyl ester; 3,5-Dibenzyloxybenzoic acid, benzyl ester. CAS No. 50513-72-9. Molecular formula: C28H24O4. Mole weight: 424.496.
Benzyl 3-Fluoro-4-(4-morpholinyl)phenyl)carbamate
Benzyl 3-Fluoro-4-(4-morpholinyl)phenyl)carbamate is an intermediate in the synthesis of Linezolid Dimer, an impurity of the antibacterial agent Linezolid. Synonyms: [3-Fluoro-4-(4-morpholinyl)phenyl]carbamic Acid Phenylmethyl Ester; N-(Benzyloxycarbonyl)-3-fluoro-4-(4-morpholinyl)aniline; N-Benzyloxycarbonyl-3-fluoro-4-morpholinoaniline; [3-Fluoro-4-(4-morpholinyl)phenyl]carbamic Acid Phenylmethyl Ester. Grades: > 95%. CAS No. 168828-81-7. Molecular formula: C18H19FN2O3. Mole weight: 330.35.
Benzyl (4-morpholinophenyl)carbamate is an impurity of Linezolid, an oxazolidinone antimicrobial that is used to treat infections against gram-positive bacteria, especially those that are drug-resistant. Linezolid works by inhibiting bacterial protein synthesis. Synonyms: N-carbobenzoxy-4-morpholinyl aniline; Linezolid Impurity 19. CAS No. 348626-43-7. Molecular formula: C18H20N2O3. Mole weight: 312.36.
Benzyl (5- ( ( (Bis (benzyloxy)phosphoryl)oxy)methyl)-2-phenyl-1, 3-dioxan-5-yl)carbamic Acid Ester is one of fosfomycin intermediates. Fosfomycin is an antibiotic that exerts a broad spectrum of antibacterial activity. It was produced by certain Streptomyces species. Synonyms: Carbamic acid, N-[5-[[[bis (phenylmethoxy) phosphinyl]oxy]methyl]-2-phenyl-1, 3-dioxan-5-yl]-, phenylmethyl ester; [5- ({[Bis (benzyloxy)phosphoryl]oxy}methyl)-2-phenyl-1, 3-dioxan-5-yl]carbamate Benzyl Ester. Molecular formula: C33H34NO8P. Mole weight: 603.60.
Benzylpenicillin Impurity 1
Benzylpenicillin Impurity 1 is an impurity of Benzylpenicillin, which is an antibiotic used to treat a number of bacterial infections. Synonyms: (2R,4S)-2-[(1R)-1-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-2-ethoxy-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid. Molecular formula: C18H25N3O6S. Mole weight: 411.47.
Benzylpenicilloic Acid Benzathide
Benzylpenicilloic Acid Benzathide is an impurity of Amoxicillin, which is an antibiotic used to treat a number of bacterial infections including middle ear infections, strep throat, pneumonia, skin infections, and urinary tract infections. Synonyms: (2R,4S)-2-[(1R)-2-[benzyl-[2-(benzylamino)ethyl]amino]-2-oxo-1-[(2-phenylacetyl)amino]ethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid; Benzathine Benzylpenicillin Impurity C (EP); Benzathine Benzyl Penicillin Impurity C (Benzylpenicilloic acids Benzathine); 4-Thiazolidinecarboxylic acid, 5, 5-dimethyl-2-[ (1R) -2-oxo-1-[ (2-phenylacetyl) amino]-2-[ (phenylmethyl) [2-[ (phenylmethyl) amino]ethyl]amino]ethyl]-, (2R,4S)-. Grades: 98%. Molecular formula: C32H38N4O4S. Mole weight: 574.73.
Benzyl Penicilloic Acid (Mixture of Diastereomers)
Benzylpenicilloic Acid is a secondary metabolites of Penicillin G. Synonyms: NSC 163084; Penicilloic G Acid; 4-Carboxy-5,5-dimethyl-α-[(2-phenylacetyl)amino]-2-thiazolidineacetic Acid; (Phenylmethyl)-Penicilloic Acid; Penicilloinsaure. Grades: ≥95%. CAS No. 13057-98-2. Molecular formula: C16H20N2O5S. Mole weight: 352.40.
Benzyl Penicilloic Acid Sodium Salt (Mixture of Diastereomers)
Cas No. 16349-25-0.
Beraprost sodium salt
Beraprost is an analog of prostacyclin in which the unstable enol-ether has been replaced by a benzofuran ether function. It inhibits platelet aggregation in healthy subjects and in diabetic patients at similar doses. Synonyms: Beraprost sodium; 4-[2-hydroxy-1-[(E)-3-hydroxy-4-methyloct-1-en-6-ynyl]-2,3,3a,8b-tetrahydro-1H-cyclopenta[b][1]benzofuran-5-yl]butanoate sodium salt. Grades: >95%. CAS No. 88475-69-8. Molecular formula: C24H29NaO5. Mole weight: 420.49.
Besifloxacin Hydrochloride
Besifloxacin HCl is a fourth-generation fluoroquinolone antibiotic that has a broad spectrum in vitro activity against a wide range of Gram-positive and Gram-negative ocular pathogens. Uses: For research used only. Synonyms: Besifloxacin hydrochloride; Besifloxacin HCl; 405165-61-9; Besifloxacin (Hydrochloride); Besivance. Grades: >98%. CAS No. 405165-61-9. Molecular formula: C19H21ClFN3O3.HCl. Mole weight: 430.3.
Bestatin hydrochloride
Bestatin hydrochloride is a competitive aminopeptidase inhibitor, which is studied for use in the treatment of acute myelocytic leukemia. It has become a useful tool in elucidating the physiological role of some mammalian exopeptidases in the regulation of the immune system, in the growth of tumors and their invasion of surrounding tissues, and in the degradation of cellular proteins. Synonyms: Aminopeptidase inhibitor; leucine aminopeptidase; aminopeptidase B; NK-421. Grades: >98%. CAS No. 65391-42-6. Molecular formula: C16H24N2O4.HCl. Mole weight: 344.83.
β-Amino-3-methoxy-4-(phenylmethoxy)benzeneethanol
β-Amino-3-methoxy-4-(phenylmethoxy)benzeneethanol is an impurity formed in the synthesis of metabolites of Epinephrine, which is a hormone and medication used to treat a number of conditions including allergic reaction anaphylaxis, cardiac arrest, and superficial bleeding. Synonyms: 2-Amino-3-methoxy-4-(phenylmethoxy)benzeneethanol; 2-Amino-2-(4-(benzyloxy)-3-methoxyphenyl)ethan-1-ol; 2-Amino-2-[4-(benzyloxy)-3-methoxyphenyl]ethanol; Benzeneethanol, β-amino-3-methoxy-4-(phenylmethoxy)-. Grades: ≥95%. CAS No. 1226258-10-1. Molecular formula: C16H19NO3. Mole weight: 273.33.
β-Asp(5)-AVP
β-Asp(5)-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: β-Asp(5)-Vasopressin; H-Cys-Tyr-Phe-Gln-β-Asp-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-β-aspartyl-L-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-disulfide. Molecular formula: C46H64N14O13S2. Mole weight: 1085.22.
Synonyms: (1S,3S)-(S)-2-Oxo-1,2-bis(3-phenoxyphenyl)ethyl 3-(2,2-dichlorovinyl)-2,2 dimethylcyclopropanecarboxylate with (1R,3R)-(R)-2-oxo-1,2-bis(3-phenoxyphenyl)ethyl 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate; Beta-Cypermethrin (1S,3S)-(S)-3-Phenoxypheny with Beta-Cypermethrin (1R,3R)-(R)-3-Phenoxypheny (Mixture). Molecular formula: C34H28Cl2O5. Mole weight: 587.49.
Betamethasone 21-Phosphate Disodium Salt
Betamethasone 21-Phosphate Disodium Salt is a derivative of Betamethasone, which is a steroid medication used for a number of diseases including rheumatic disorders, skin diseases and allergic conditions. Synonyms: (11β,16β)-9-Fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)pregna-1,4-diene-3,20-dione Sodium Salt; 9-Fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione 21-(Dihydrogen Phosphate) Sodium Salt; Betnesol; Durabetason; NSC 90616; Steronema; Vista-Methasone; Dexamethasone Sodium Phosphate EP Impurity B. Grades: 97%. CAS No. 151-73-5. Molecular formula: C22H28FNa2O8P. Mole weight: 516.40.
Betamethasone Dipropionate
Cas No. 5593-20-4.
β-MSH (human)
β-MSH (human) is a melanocortin (MC) receptor agonist. Synonyms: Beta-MSH (1-22) (human); β-Melanocyte Stimulating Hormone (MSH), human; b-Melanotropin (human); ALA-GLU-LYS-LYS-ASP-GLU-GLY-PRO-TYR-ARG-MET-GLU-HIS-PHE-ARG-TRP-GLY-SER-PRO-PRO-LYS-ASP; Melanocyte stimulating hormone, beta-human; H-ALA-GLU-LYS-LYS-ASP-GLU-GLY-PRO-TYR-ARG-MET-GLU-HIS-PHE-ARG-TRP-GLY-SER-PRO-PRO-LYS-ASP-OH. Grades: ≥95% by HPLC. CAS No. 17908-57-5. Molecular formula: C118H174N34O35S. Mole weight: 2660.94.
(βS,δS)-Atorvastatin tert-Butyl Ester
(βS,δS)-Atorvastatin tert-Butyl Ester is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Synonyms: (3S,5S)-tert-butyl 7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate; 2-Methyl-2-propanyl (3S,5S)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate; (βS,δS)-2-(4-Fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid 1,1-Dimethylethyl Ester. CAS No. 1428118-12-0. Molecular formula: C37H43FN2O5. Mole weight: 614.75.