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CGS 15943
CGS 15943 is a potent and orally bioactive adenosine receptor antagonist (Ki = 3.5, 4.2, 16 and 51 nM for human A1, A2A, A2B and A3 receptors, respectively). Synonyms: CGS 15943; CGS15943; CGS-15943; 9-Chloro-2-(2-furanyl)-[1,2,4]triazolo[1,5-c]quinazolin-5-amine. Grades: ≥99% by HPLC. CAS No. 104615-18-1. Molecular formula: C13H8ClN5O. Mole weight: 285.69.
CH5424802 Hydrochloride
CH5424802 Hcl (AF 802 Hcl; Alectinib Hcl) is a potent ALK inhibitor with IC50 of 1.9 nM, sensitive to L1196M mutation. Synonyms: Alectinib Hydrochloride; AF-802 Hydrochloride; CH-5424802 Hydrochloride; RG-7853 Hydrochloride; RO-5424802 Hydrochloride; AF 802 Hydrochloride; CH 5424802 Hydrochloride; RG 7853 Hydrochloride; RO 5424802 Hydrochloride; AF802 Hydrochloride; CH5424802 Hydrochloride; RG7853 Hydrochloride; RO5424802 Hydrochloride. Grades: >98%. CAS No. 1256589-74-8. Molecular formula: C30H35ClN4O2. Mole weight: 519.08.
CH 55
CH 55 is an impurity of Retinoic acid. Retinoic Acid is a metabolite of Vitamin A and ajusts its functions of cellular growth and differentiation. Synonyms: Ch55; Ch-55; Ch 55. 4-[(1E)-3-[3,5-Bis(1,1-dimethylethyl)phenyl]-3-oxo-1-propen-1-yl]benzoic Acid; (E)-4-[3-[3,5-bis(1,1-dimethylethyl)phenyl]-3-oxo-1-propenyl]-benzoic Acid; Benzoic acid, 4-(3-(3,5-bis(1,1-dimethylethyl)phenyl)-3-oxo-1-propenyl)-, (E)-. Grades: ≥98% by HPLC. CAS No. 110368-33-7. Molecular formula: C24H28O3. Mole weight: 364.48.
CHIR-090
CHIR-090 is a very potent and tight-binding inhibitor of LpxC, which is a zinc-dependent amidase and present in almost all Gram-negative bacteria, and is a promising target for the development of novel antibiotic substances against multigrug-resistant Gram-negative bacteria. Its Ki value is 4.0 nM. It displays two-step time-dependent inhibition and kills a wide range of Gram-negative pathogens as effectively as ciprofloxacin or tobramycin. It has a different selectivity with the reported LpxC inhibitor L-161. It has excellent antibiotic activity against Pseudomonas aeruginosa and Escherichia coli by inhibiting LpxC orthologs at low nM concentrations. It is an excellent lead for the further development of new antibiotics targeting the lipid A pathway. Uses: Chir-090 displays two-step time-dependent inhibition and kills a wide range of gram-negative pathogens as effectively as ciprofloxacin or tobramycin. it has excellent antibiotic activity against pseudomonas aeruginosa and escherichia coli by inhibiting lpxc orthologs at low nm concentrations. Synonyms: CHIR-090; CHIR 090; CHIR090. N-[ (1S, 2R) -2-Hydroxy-1-[ (hydroxyamino) carbonyl]propyl]-4-[[4- (4-morpholinylmethyl) phenyl]ethynyl]benzamide. Grades: 98%. CAS No. 728865-23-4. Molecular formula: C24H27N3O5. Mole weight: 437.49.
Chlophedianol hydrochloride
Chlophedianol hydrochloride is a centrally-acting cough suppressant. It is used in the treatment of dry cough. It has local anesthetic and antihistamine properties, and may have anticholinergic effects at high doses. It has been listed. Uses: Chlophedianol hydrochloride is used in the treatment of dry cough. Synonyms: Chlophedianol HCl; Coldrin; Detigon; Pectolitan; Refugal; 2-Chloro-alpha-(2-dimethylaminoethyl)benzhydrol; Baltix; 1-(2-Chlorophenyl)-3-(dimethylamino)-1-phenylpropan-1-ol hydrochloride; 1-o-Chlorophenyl-1-phenyl-3-dimethylamino-1-propanol hydrochloride. Grades: 95%. CAS No. 511-13-7. Molecular formula: C17H21Cl2NO. Mole weight: 326.26.
Chloromethyl (S,R)-Palonosetron Chloride
Chloromethyl (S,R)-Palonosetron Chloride is a by-product of (S,R)-Palonosetron Hydrochloride. Molecular formula: C20H26Cl2N2O. Mole weight: 381.34.
Chloropyramine Impurity 1 HCl
Tripelennamine hydrochloride, the hydrochloride salt form of tripelennamine, is a blood-brain barrier penetrant and orally active H1 receptor antagonist. Tripelennamine, also known as Pyribenzamine, exhibits antipruritic and first-generation antihistamine properties. Uses: Anti-allergic agents. Synonyms: Tripelennamine HCl; Ahistamin; Piristin; N'-benzyl-N,N-dimethyl-N'-pyridin-2-ylethane-1,2-diamine hydrochloride. Grades: > 95%. CAS No. 154-69-8. Molecular formula: C16H22ClN3. Mole weight: 291.82.
Chlorothiazide
Chlorothiazide is a thiazide diuretic used for the treatment of edema caused by various medical problems. Chlorothiazide is also an impurity of Hydrochlorothiazide. Synonyms: Diuril. CAS No. 58-94-6. Molecular formula: C7H6ClN3O4S2. Mole weight: 295.72.
Choline Fenofibrate is the choline salt of fenofibric acid under clinical development as a combination therapy with rosuvastatin for the management of dyslipidemia. Synonyms: ABT-335; ABT 335; ABT335; HIP0901; HIP-0901; HIP 0901; Choline fenofibrate; Trilipix. Fibricor; fenofibric acid. Grades: >98%. CAS No. 856676-23-8. Molecular formula: C22H28ClNO5. Mole weight: 421.91.
Cibinetide
Cibinetide is a non-erythropoietic erythropoietin (EPO) derivative. It acts as a specific agonist of erythropoietin/CD131 heteroreceptor, and is under clinical trials for the treatment of diabetic macular edema. Synonyms: ARA-290; ARA 290; ARA290; PHBSP; PH-BSP; PH BSP; H-Pyr-Glu-Gln-Leu-Glu-Arg-Ala-Leu-Asn-Ser-Ser-OH. Grades: >98%. CAS No. 1208243-50-8. Molecular formula: C51H84N16O21. Mole weight: 1257.3.
Ciclopirox
Ciclopirox olamine (used in preparations called Batrafen, Loprox, Rejuvenail, Mycoster, Penlac and Stieprox) is a synthetic antifungal agent for topical dermatologic treatment of superficial mycoses. It is most useful against Tinea versicolor. Synonyms: Ciclopirox. Grades: >98%. CAS No. 29342-05-0. Molecular formula: C12H17NO2. Mole weight: 207.27.
Ciclopirox ethanolamine
Ciclopirox ethanolamine (Ciclopirox olamine, HOE 296) is a broad-spectrum antifungal agent working as an iron chelator. Uses: Antifungal agents. Synonyms: Ciclopirox olamine; 41621-49-2; Ciclopirox ethanolamine; ciclopiroxolamine; Batrafen; Micoxolamina; Brumixol; Mycoster; Ciclopiroxolamin; Ciclochem; Dafnegin; Ciclopirox (olamine); HOE 296; Ciclopirox ethanolamine salt (1:1); HOE-296; UNII-50MD4SB4AP; EINECS 255-464-9; 50MD4SB4AP; NSC 336278; NSC-336278; DTXSID6045583; RV4104A; MFCD00078997; 6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone ethanolamine salt; Ciclobirox Olamine; 6-Cyclohexyl-1-hydroxy-4-methylpyridin-2(1H)-one compound with 2-aminoethanol (1:1); MLS003170863; 2-aminoethanol; 6-cyclohexyl-1-hydroxy-4-methylpyridin-2-one. Grades: >98%. CAS No. 41621-49-2. Molecular formula: C12H17NO2.C2H7NO. Mole weight: 268.35.
CID-25014542
CID-25014542 is a Raf kinase inhibitor. Synonyms: CID-25014542; CID25014542; CID 25014542. 5-Chloro-3-(3,5-dibromo-4-hydroxybenzylidene)indolin-2-one; (3Z)-5-chloro-3-[(3,5-dibromo-4-hydroxyphenyl)methylidene]-1H-indol-2-one. CAS No. 220904-99-4. Molecular formula: C15H8Br2ClNO2. Mole weight: 429.492.
CID5721353
CID5721353 is a B-Cell Lymphoma 6 Inhibitor (BCL6 inhibitor) that disrupts BCL6/corepressor complexes in vitro and in vivo, and was shown to bind the critical site within the BTB groove. Synonyms: 2-((5Z)-5-(5-Bromo-2-oxo-1H-indol-3-ylidene)-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl)butanedioic acid; CID5721353; CID-5721353; CID 5721353; BCL6 Inhibitor, 79-6. CAS No. 301356-95-6. Molecular formula: C15H9BrN2O6S2. Mole weight: 457.26.
Cilastatin Ammonium Salt
Cilastatin Ammonium Salt is the ammonium salt of Cilastatin, which is a dipeptidase inhibitor of renal enzyme dehydropeptidase-I and leukotriene D4 peptidase. It inhibits metabolism of LTD4 to LTE4 and the hydrolysis of β-lactam antibiotics. It reduces toxic accumulation of cyclosporin A in kidney proximal tubule epithelial cells. It can be combined intravenously with imipenem in order to protect it from dehydropeptidase. It suppresses both host and target metabolism of the broad-spectrum antibiotic imipenem, improving its efficacy. It usually confers antibiotic resistance to certain bacteria because itself does not have antibiotic activity. It has nephroprotective effects. Synonyms: (2Z)-7-[[(2R)-2-amino-2-carboxyethyl]thio]-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-2-heptenoic Acid Ammonium Salt; MK-791 Ammonium Salt. Grades: > 95%. CAS No. 877674-82-3. Molecular formula: C16H29N3O5S. Mole weight: 375.48.
Cilastatin sodium
Cilastatin sodium is the sodium salt of cilastatin, which is a dipeptidase inhibitor of renal enzyme dehydropeptidase-I and leukotriene D4 peptidase. It inhibits metabolism of LTD4 to LTE4 and the hydrolysis of β-lactam antibiotics. It reduces toxic accumulation of cyclosporin A in kidney proximal tubule epithelial cells. It can be combined intravenously with imipenem in order to protect it from dehydropeptidase. It suppresses both host and target metabolism of the broad-spectrum antibiotic imipenem, improving its efficacy. It usually confers antibiotic resistance to certain bacteria because itself does not have antibiotic activity. It has nephroprotective effects. Synonyms: L 642957; MK 791; L642957; MK791; L-642957; MK-791; [R-[R*,S*-(Z)]]-7-[(2-Amino-2-carboxyethyl)thio]-2-[[(2,2-dimethylcyclopropyl)carbonyl]amino]-2-heptenoic Acid Monosodium Salt; (2Z) ?-7- [ [ (2R) ?-2-Amino-2-carboxyethyl] ?thio] ?-2- [ [ [ (1S) ?-2, ?2-dimethylcyclopropyl] ?carbonyl] ?amino] ?-2-heptenoic Acid Sodium Salt; sodium S-((Z)-6-carboxy-6-((S)-2,2-dimethylcyclopropane-1-carboxamido)hex-5-en-1-yl)-L-cysteinate. Grades: ≥99% by HPLC. CAS No. 81129-83-1. Molecular formula: C16H25N2NaO5S. Mole weight: 380.43.
Cilofexor
Cilofexor is a farnesoid X receptor (FXR) agonist. Cilofexor inhibits binding of a synthetic peptide, comprising residues 676-700 of the steroid receptor coactivator 1 (SRC-1), to the farnesoid X receptor (FXR; EC50 = <25 nM in a FRET activity assay). Synonyms: 2-[3-[2-chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-4-isoxazolyl]methoxy]phenyl]-3-hydroxy-1-azetidinyl]-4-pyridinecarboxylic acid. Grades: ≥98%. CAS No. 1418274-28-8. Molecular formula: C28H22Cl3N3O5. Mole weight: 586.9.
Cimaterol
Cimaterol is a β-adrenergic agonist, related to Clenbuterol and Mabuterol. It is also a repartitioning agent. Uses: Adrenergic beta-agonists. Synonyms: Cimater; 2-Amino-5-[1-hydroxy-2-[ (1-methylethyl) amino]ethyl]benzonitrile; CL 263780; Cimaterolum. Grades: 98%. CAS No. 54239-37-1. Molecular formula: C12H17N3O. Mole weight: 219.28.
Ciraparantag
Ciraparantag, also called as PER977, a synthetic, cationic small molecule, has potential to be a simple, inexpensive universal anticoagulation reversal agent. Synonyms: PER-977; PER 977; PER977; Aripazine. CAS No. 1438492-26-2. Molecular formula: C22H48N12O2. Mole weight: 512.71.
cis-10,11-Dihydroxy-10,11-dihydrocarbamazepine
Cis-10,11-Dihydroxy-10,11-dihydrocarbamazepine is a metabolite of Carbamazepine, which is used in treatment of pain associated with trigeminal neuralgia. Synonyms: (10R,11S)-rel-10,11-Dihydro-10,11-dihydroxy-5H-dibenz[b,f]azepine-5-carboxamide; cis-10,11-Dihydro-10,11-dihydroxycarbamazepine; 5H-Dibenz[b,f]azepine-5-carboxamide, 10,11-dihydro-10,11-dihydroxy-, (10R,11S)-rel-; cis-10,11-dihydro-10,11-dihydroxy-5H-dibenzazepine-5-carboxamide; 5H-Dibenz(b,f)azepine-5-carboxamide, 10,11-dihydro-10,11-dihydroxy-, cis-; cis-10,11-Dihydroxy-10,11-dihydrocarbamazepine; CGP 5924. Grades: ≥95%. CAS No. 58955-94-5. Molecular formula: C15H14N2O3. Mole weight: 270.28.
cis-1,4-Cyclohexanediol
cis-1,4-Cyclohexanediol is a metabolite of the side-chain of candesartan cilexetil, which is an angiotensin receptor blocker used mainly for the treatment of high blood pressure and congestive heart failure. Synonyms: cis-Cyclohexane-1,4-diol; cis-Hexahydrohydroquinone; cis-Quinitol; cis-1,4-Dihydroxycyclohexane. Grades: ≥95%. CAS No. 931-71-5. Molecular formula: C6H12O2. Mole weight: 116.16.
cis-1-Hydroxy-2,7-diamino Mitosene
cis-1-Hydroxy-2,7-diamino Mitosene is derived from Mitomycin C. Mitomycin is a drug which is used for treatment of malignant neoplasm of lip. Synonyms: (1S,2S)-2,7-Diamino-9-[[(aminocarbonyl)oxy]methyl]-2,3-dihydro-1-hydroxy-6-methyl-1H-pyrrolo[1,2-a]indole-5,8-dione; (1S-cis)-2,7-Diamino-9-[[(aminocarbonyl)oxy]methyl]-2,3-dihydro-1-hydroxy-6-methyl-1H-Pyrrolo[1,2-a]indole-5,8-dione; 1,2-cis-1-Hydroxy-2,7-diamino-mitosene; Mitomycin Impurity 7; Mitomycin Related Compound 2. Grades: ≥95%. CAS No. 98462-75-0. Molecular formula: C14H16N4O5. Mole weight: 320.30.
cis-2-Butene-1,4-diol
cis-2-Butene-1,4-diol is an impurity of Gadobutrol, which is a nonionic, paramagnetic contrast agent developed for tissue contrast enhancement in magnetic resonance imaging (MRI). Synonyms: 2-Butene-1,4-diol, (2Z)-; (2Z)-2-Butene-1,4-diol; 2-Butene-1,4-diol, (Z)-; 2-Butene-1,4-diol, cis-; (Z)-1,4-Dihydroxy-2-butene; (Z)-2-Buten-1,4-diol; (Z)-2-Butene-1,4-diol; cis-1,4-Dihydroxy-2-butene; cis-But-2-en-1,4-diol. Grades: 95%. CAS No. 6117-80-2. Molecular formula: C4H8O2. Mole weight: 88.11.
An impurity of Ambroxol. Synonyms: cis-4-Hydroxycyclohexylamine hydrochloride. Grades: > 95%. CAS No. 56239-26-0. Molecular formula: C6H13NO. HCl. Mole weight: 151.63.
Cisatracurium-20-methyl Dibenzenesulfonate
Cisatracurium-20-methyl Dibenzenesulfonate is an impurity of Cisatracurium, an enantiomer of a neuromuscular blocking agent. Synonyms: (1R,1'R,2R,2'R)-2,2'-((Hexane-1,6-diylbis(oxy))bis(3-oxopropane-3,1-diyl))bis(1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium)Henzenesulfonate; (1R,1'R,2R,2'R)-2,2'-[1,6-Hexanediylbis[oxy(3-oxo-3,1-propanediyl)]]bis[1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methylisoquinolinium Benzenesulfonate. CAS No. 1193104-85-6. Molecular formula: C66H84N2O18S2. Mole weight: 1257.51.
cis-Clopidogrel L-Cysteine Disulfide (Mixture of Diastereomers)
cis-Clopidogrel L-Cysteine Disulfide (Mixture of Diastereomers) is an active metabolite of Clopidogrel, which is an antiplatelet medication used to reduce the risk of heart disease and stroke in those at high risk. Synonyms: S-((2-(3-(carboxymethylene)-1-(1-(3-chlorophenyl)-2-methoxy-2-oxoethyl)piperidin-4-yl)ethyl)thio)-L-homocysteine; 3-[[3-(carboxymethylene)-1-[1-(2-chlorophenyl)-2-methoxy-2-oxoethyl]-4-piperidinyl]dithio]-L-cysteine. Molecular formula: C20H25ClN2O6S2. Mole weight: 489.00.
cis-Clopidogrel N-acetyl-L-Cysteine Disulfide (Mixture of Diastereomers)
cis-Clopidogrel N-acetyl-L-Cysteine Disulfide (Mixture of Diastereomers) is an active metabolite of Clopidogrel, which is an antiplatelet medication used to reduce the risk of heart disease and stroke in those at high risk. Synonyms: (2S)-2-Acetamido-4-({(3Z)-3-(carboxymethylene)-1-[1-(3-chlorophenyl)-2-methoxy-2-oxoethyl]-4-piperidinyl}disulfanyl)butanoic acid; 1-Piperidineacetic acid, 4-[[(3S)-3-(acetylamino)-3-carboxypropyl]dithio]-3-(carboxymethylene)-α-(3-chlorophenyl)-, α-methyl ester, (3Z)-. Molecular formula: C22H27ClN2O7S2. Mole weight: 531.04.
cis-Crotylboronic acid pinacol ester
cis-Crotylboronic acid pinacol ester is a vital compound used in the biomedical industry. It exhibits potential therapeutic effects against specific diseases, including certain types of cancers and metabolic disorders. Through its unique chemical properties, cis-Crotylboronic acid pinacol ester holds promise as a valuable tool for drug development and targeted therapies in the field of biomedicine. Synonyms: Z-2-Buten-1-yl-boronic acid pinacol ester; Z-Crotylboronic acid pinacol ester; cis-2-(2-Buten-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane. Grades: 95%. CAS No. 69611-01-4. Molecular formula: C10H19BO2. Mole weight: 182.07.
cis-Cypermethrin Benzaldehyde
cis-Cypermethrin Benzaldehyde is an impurity of Cypermethrin, which is a synthetic pyrethroid used as an insecticide. Synonyms: 2-Oxo-1-(3-phenoxyphenyl)-2-phenylethyl (1S,3S)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate; cis-Cypermethrin Impurity; (1S,3S)-2-Oxo-1-(3-phenoxyphenyl)-2-phenylethyl 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate; Cypermethrin Impurity 7 (cis, 4 isomers); Cyclopropanecarboxylic acid, 3-(2,2-dichloroethenyl)-2,2-dimethyl-, 2-oxo-1-(3-phenoxyphenyl)-2-phenylethyl ester, (1S,3S)-. Molecular formula: C28H24Cl2O4. Mole weight: 495.39.
2a, 4a, 6a, 8a-Decahydrotetraazacyclopent [fg]acenaphthylene is an intermediate of Gadoteridol. Gadoterido is a gadolinium-based MRI contrast agent. It is sold under the brand name ProHance. Synonyms: Decahydro-cis-2a,4a,6a,8a-tetraazacyclopent[fg]acenaphthylene; cis-2a, 4a, 6a, 8a-Decahydrotetraazacyclopent [fg]acenaphthylene; cis-Glyoxal-cyclen; 2a,4a,6a,8a-Tetraazacyclopent[fg]acenaphthylene, decahydro-, cis-. Grades: 98%. CAS No. 79236-92-3. Molecular formula: C10H18N4. Mole weight: 194.28.
(+/-)-(cis)-Dorzolamide
(+/-)-(cis)-Dorzolamide is an isomer of Dorzolamide. Dorzolamide is a carbonic anhydrase inhibitor. It is an anti-glaucoma agent, and acts by decreasing the production of aqueous humour. Synonyms: (4R,6S)-4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide. CAS No. 120279-90-5. Molecular formula: C10H16N2O4S3. Mole weight: 324.44.
cis-N-Ethyl-2-(hydroxymethyl)-1-phenylcyclopropanecarboxamide is an intermediate in the synthesis of Milnacipran, which is a serotonin-norepinephrine reuptake inhibitor (SNRI) used in the clinical treatment of fibromyalgia. Synonyms: Rel-(1R,2S)-N-ethyl-2-(hydroxymethyl)-1-phenylcyclopropane-1-carboxamide. CAS No. 69160-65-2. Molecular formula: C13H17NO2. Mole weight: 219.28.
cis-(+)-Paroxetine
An impurity of Paroxetine which is a selective serotonin reuptake inhibitor. Synonyms: (3S-cis)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine; cis-(+)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine; USP Paroxetine Related Compound D. CAS No. 1396174-70-1. Molecular formula: C19H20FNO3. Mole weight: 329.37.
cis-Permethrin
cis-Permethrin is the cis-isomer of Permethrin, which is a medication and an insecticide used to treat scabies and lice. Uses: Enzyme inhibitors. Synonyms: Cyclopropanecarboxylic acid, 3-(2,2-dichloroethenyl)-2,2-dimethyl-, (3-phenoxyphenyl)methyl ester, (1R,3R)-rel-; Cyclopropanecarboxylic acid, 3-(2,2-dichloroethenyl)-2,2-dimethyl-, (3-phenoxyphenyl)methyl ester, cis-; (±)-cis-FMC 33297; (±)-cis-Permethrin; 1RS,cis-Permethrin; Cispermethrin; FMC 35171; NRDC 148. Grades: 98%. CAS No. 61949-76-6. Molecular formula: C21H20Cl2O3. Mole weight: 391.29.
An impurity of Paroxetine which is a selective serotonin reuptake inhibitor. Synonyms: Paroxetine Impurity 24. Grades: >95%. CAS No. 105812-85-9. Molecular formula: C26H24FNO5. Mole weight: 449.48.
CJC1295 Without DAC
CJC-1295 is a 30-amino acid peptide and a growth hormone releasing hormone (GHRH) analog. It prolongs stimulation of growth hormone (GH) and insulin-like growth factor I secretion. It also extends the half-life and bioavailability of growth-hormone-releasing hormone 1-29. Synonyms: CJC 1295; CJC1295; L-tyrosyl-D-alanyl-L-alpha-aspartyl-L-alanyl-L-isoleucyl-L-phenylalanyl-L-threonyl-L-glutaminyl-L-seryl-L-tyrosyl-L-arginyl-L-lysyl-L-valyl-L-leucyl-L-alanyl-L-glutaminyl-L-leucyl-L-seryl-L-alanyl-L-arginyl-L-lysyl-L-leucyl-L-leucyl-L-glutaminyl-L-alpha-aspartyl-L-isoleucyl-L-leucyl-L-seryl-L-argininamide. Grades: >98%. CAS No. 863288-34-0. Molecular formula: C152H252N44O42. Mole weight: 3367.9.
CKD 602
CKD-602 is a topoisomerase I inhibitor. It is a synthetic and water-soluble camptothecin derivative which forms stable DNA-topoisomerase complexes during DNA replication and induces cell cycle arrest in the G2/M phase. CKD-602 has a significant effect on intracerebral glioma growth, with animals having significantly smaller tumors than those in the control group. Synonyms: (4S)-4-Ethyl-4-hydroxy-11-[2-[(1-methylethyl)amino]ethyl]-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)dione phosphate; Belotecan hydrochloride. Grades: ≥98% by HPLC. CAS No. 213819-48-8. Molecular formula: C25H27N3O4·H3PO4. Mole weight: 531.49.
CL-387785
CL-387785, also known as EKI-785, is an irreversible inhibitor of EGF-receptor (EGFR) kinase activity in vivo (IC50 = 250-490 pM). CL-387785 covalently bound to EGF-R. It also specifically inhibited kinase activity of the protein (IC50 = 370+/-120 pM), blocked EGF-stimulated autophosphorylation of the receptor in cells (ic50 approximately 5 nM), inhibited cell proliferation (IC50 = 31-125 nM) primarily in a cytostatic manner in cell lines that overexpress EGF-R or c-erbB-2, and profoundly blocked the growth of a tumor that overexpresses EGF-R in nude mice (when given orally at 80 mg/kg/day for 10 days, daily). CL-387,785 is useful for studying the interaction of small molecules with EGF-R and may have clinical utility. Uses: Protein kinase inhibitors. Synonyms: CL-387785; CL 387785; CL-387,785; CL387785; EKI-785; EKI 785; EKI785. Grades: 0.98. CAS No. 194423-06-8. Molecular formula: C18H13BrN4O. Mole weight: 381.233.
Clemizole hydrochloride
The hydrochloride salt form of clemizole, which is a histamine H1 antagonist with antitumor activity. It also has hepatitis C antiviral effect through restraining NS4B function and could also be used as an anticonvulsant in zebrafish Dravet syndrome model. Synonyms: Allercur; Clemizole HCl; Clemizole (hydrochloride); Reactrol; 1-[(4-chlorophenyl)methyl]-2-(pyrrolidin-1-ylmethyl)benzimidazole hydrochloride. Grades: 95%. CAS No. 1163-36-6. Molecular formula: C19H20ClN3.HCl. Mole weight: 362.30.
Clencyclohexerol
Clencyclohexerol is an analog of Clenbuterol and is used as a reagent in the synthesis of pyrazolopyridine derivatives as inhibitors of phosphodiesterase-4 (PDE-IV) and production of tumor necrosis factor-α (TNF-α). Uses: An analog of clenbuterol, a β-agonist which can be used as a growth promoter in farm animals. Synonyms: 4-Amino-3, 5-dichloro-α -[[ (4-hydroxycyclohexyl) amino]methyl]benzenemethanol; Benzenemethanol, 4-amino-3,5-dichloro-α-[[(4-hydroxycyclohexyl)amino]methyl]-; 4-{[2-(4-Amino-3,5-dichlorophenyl)-2-hydroxyethyl]amino}cyclohexanol. Grades: 98%. CAS No. 157877-79-7. Molecular formula: C14H20Cl2N2O2. Mole weight: 319.23.
Clevudine
Clevudine is an inhibitor of hepatitis B virus (HBV). It is metabolized in cells by the cellular thymidine kinase as well as deoxycytidine kinase to its monophosphate, and subsequently to the di- and triphosphate, which are biologically active. Uses: Antiviral agents. Synonyms: 1-(2'-Deoxy-2'-fluoro-β-L-arabinofuranosyl)-5-methyluracil; L-FMAU; 1-(2-Deoxy-2-fluoro-β-L-arabinofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione; L FMAU; LFMAU; Levovir; 2'-Fluoro-5-methyl-b-L-arabinofuranosyluracil. Grades: ≥98% by HPLC. CAS No. 163252-36-6. Molecular formula: C10H13FN2O5. Mole weight: 260.22.
Clinafloxacin
Clinafloxacin is a fluoroquinolone antibiotic with a broad-range of antibacterial activity. It inhibits both DNA gyrase and topoisomerase IV. Synonyms: 7-(3-aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid. Grades: >98%. CAS No. 105956-97-6. Molecular formula: C17H17ClFN3O3. Mole weight: 365.79.
Clindamycin Hydrochloride
Clindamycin hydrochloride(Dalacin) is the hydrated hydrochloride salt of clindamycin which is a semisynthetic antibiotic. Clindamycin is a lincosamide antibiotic. An impurity of Clindamycin which is a semi-synthetic antibiotic prepared from Lincomycin. Synonyms: (2S-trans)-Methyl 7-Chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-L-threo-α-D-galactooctopyranoside Hydrochloride; 7(S)-Chloro-7-deoxylincomycin; 7-CDL; 7-Chloro-7-deoxylincomycin; 7-Chlorolincomycin; Antirobe; Chlolincocin; Cleocin; Clinimycin; Dalacine; Clindamycin Phosphate EP Impurity E. Grades: >98%. CAS No. 21462-39-5. Molecular formula: C18H34Cl2N2O5S. Mole weight: 461.44.
Clinofibrate
Clinofibrate inhibits hydroxymethylglutaryl coenzyme A reductase (HMGCR) with IC50 of 0.47 mM, is a lipid-lowering agent used for controlling high cholesterol and triacylglyceride levels in the blood. Synonyms: Lipoclin; S-8527; butanoic acid, 2,2'-[cyclohexylidenebis(4,1-phenyleneoxy)]bis[2-methyl-. Grades: >98%. CAS No. 30299-08-2. Molecular formula: C28H36O6. Mole weight: 468.58.
Clobetasol Propionate
Clobetasol propionate is a glucocorticoid that induces monooxygenase activity in vivo. It alters the structure of tight junctions in epidermis and smoothened hedgehog pathway receptor agonist. It can be used as anti-inflammatory, immunosuppressive and antimitotic agent. Active in vivo. Uses: Anti-inflammatory, immunosuppressive and antimitotic agent. Synonyms: Clobex; Cosvate (India); Temovate (US); Olux; Tenovate; Dermovate; Dermatovate; Butavate; Movate; Novate; [17-(2'-chloroacetyl)- 9-fluoro-11-hydroxy-10,13,16-trimethyl- 3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate. Grades: 0.99. CAS No. 25122-46-7. Molecular formula: C25H32ClFO5. Mole weight: 466.974.
Clobetasol Propionate EP Impurity G
An impurity of Clobetasol propionate. Clobetasol propionate is a corticosteroid of the glucocorticoid class used to treat various skin disorders including eczema and psoriasis. It is also highly effective for contact dermatitis caused by exposure to poison ivy/oak. Uses: Anti-inflammatory agents; glucocorticoids. Synonyms: (11β,16β)-21-Chloro-9-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione; 21-Chloro-9-fluoro-11β,17-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione; Clobetasol Propionate EP Impurity G;Clobetasol. Grades: > 95%. CAS No. 25122-41-2. Molecular formula: C22H28ClFO4. Mole weight: 410.92.
Clocortolone
Corticosteroid used in the treatment of skin inflammmation and other skin conditions arising for dermatoses. Uses: Anti-inflammatory agents. Synonyms: (6α,11β,16α)-9-Chloro-6-fluoro-11,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione; 9-Chloro-6α-fluoro-11β,21-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione. Grades: > 95%. CAS No. 4828-27-7. Molecular formula: C22H28ClFO4. Mole weight: 410.92.
Clocortolone caproate
Clocortolone caproate is a derivative of Clocortolone. Synonyms: (6α,11β,16α)-9-Chloro-6-fluoro-11-hydroxy-16-methyl-21-[(1-oxohexyl)oxy]-pregna-1,4-diene-3,20-dione; 9-Chloro-6α-fluoro-11β,21-dihydroxy-16α-methyl-pregna-1,4-diene-3,20-dione 21-Hexanoate. Grades: > 95%. CAS No. 4891-71-8. Molecular formula: C28H38ClFO5. Mole weight: 509.06.
Clodronate disodium tetrahydrate
Clodronate is a non-nitrogenous bisphosphonate that can bind to bone to reduce the bone resorption. It is used as an anti-osteoporotic drug for the prevention of osteoporosis in post-menopausal women and men. Uses: The treatment of osteoporosis. Synonyms: (Dichloromethylene)bisphosphonic Acid Disodium Salt Tetrahydrate; Sodium clodronate hydrate; Disodium [dichloro (phosphonato)methyl]phosphonic acid tetrahydrate. Grades: >98%. CAS No. 88416-50-6. Molecular formula: CH10Cl2Na2O10P2. Mole weight: 360.908.
Clofedanol O-β-D-Glucuronide is a metabolite of the cough suppressant Clofedanol. Synonyms: 1-(2-Chlorophenyl)-3-(dimethylamino)-1-phenylpropyl β-D-Glucopyranosiduronic Acid; Clophedianol O-β-D-Glucuronide. Grades: > 95%. CAS No. 66171-85-5. Molecular formula: C23H28ClNO7. Mole weight: 465.92.
Clomifene citrate
Clomifene Citrate is a selective estrogen receptor modulator used in the treatment of ovulation induction. It is used to treat breast cancer for its antineoplastic activity. Uses: The treatment of breast cancer. Synonyms: NSC 35770; NSC35770; NSC-35770; CLOMIPHENE CITRATE; Zuclomiphene citrate; Clomivid; Clomphid. Grades: >98%. CAS No. 50-41-9. Molecular formula: C26H28ClNO.C6H8O7. Mole weight: 598.08.
Clonidine Impurity 1
N-(2,6-dichlorophenyl)-carbonimidic Dichloride is an impurity of clonidine. Chlonidine is an α2-Adrenergic agonist. Synonyms: N-(2,6-Dichlorophenyl)-carbonimidic Dichloride; (2,6-Dichlorophenyl)carbonimidic Dichloride. Grades: > 95%. CAS No. 21709-18-2. Molecular formula: C7H3Cl4N. Mole weight: 242.92.
Clonidine Impurity A
Clonidine Impurity A is an impurity of Clonidine, a predominantly employed for the therapy of hypertensive ailments. Synonyms: 1-Acetyl-2-imidazolidinone. Grades: > 95%. CAS No. 5391-39-9. Molecular formula: C5H8N2O2. Mole weight: 128.13.
Clonidine Related Compound A
Acetylcholidine is an impurity in the synthesis of Clonidine, an α2-Adrenergic agonist. Synonyms: Acetylclonidine; 1-Acetyl-N-(2,6-dichlorophenyl)-4,5-dihydro-1H-Imidazol-2-amine; SKF 34874. Grades: > 95%. CAS No. 54707-71-0. Molecular formula: C11H11Cl2N3O. Mole weight: 272.13.
Clopidogrel Bisulfate Impurity B
Clopidogrel Bisulfate Impurity B is an impurity of Clopidogrel, an antithrombotic agent. Synonyms: methyl (S)-(+)-2-(2-chlorophenyl)-2-(4,5-dihydrothieno[2,3-c]pyridin-6(7H)-yl)acetate; methyl (S)-2-(2-chlorophenyl)-2-(4,7-dihydrothieno[2,3-c]pyridin-6(5H)-yl)acetate. CAS No. 1396841-05-6. Molecular formula: C16H16ClNO2S. Mole weight: 321.82.
Clopidogrel sulfate
Clopidogrel Bisulfate is a thienopyridine with antiplatelet activity. It is used to prevent thromboembolism in patients with arterial occlusive disease, Myocardial infarction, Stroke, Or atrial fibrillation. Uses: Platelet aggregation inhibitors. Synonyms: Clopidogrel hydrogen sulfate; Iscover; Plavix; (S)-methyl 2-(2-chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate sulfate. Grades: 98%. CAS No. 120202-66-6. Molecular formula: C16H18ClNO6S2. Mole weight: 419.90.
Cloprostenol sodium is a synthetic and water-soluble aryl-oxymethyl analog of prostaglandin F2&alpha. lt is also a potent inhibitor of rat adipose precursor differentiation in primary cultures. It has luteolytic effects and is used for the synchronization of estrus in cattle. It is also used for the treatment of infertility in sows and gilts. Uses: Luteolytic agents. Synonyms: ICI 80996; ICI-80996; ICI 80996; ICI 80,996; ICI-80,996; ICI 80,996; DL-Cloprostenol sodium; Estroplan; Estrumate;DL-Cloprostenol sodium;Estroplan;Estrumate;sodium (Z)-7-(2-((E)-4-(3-chlorophenoxy)-3-hydroxybut-1-en-1-yl)-3,5-dihydroxycyclopentyl)hept-5-enoate;5-Heptenoicacid,7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-chlorophenoxy)-3-hydroxy-1-butenyl]-3,5-. Grades: >98%. CAS No. 55028-72-3. Molecular formula: C22H28ClNaO6. Mole weight: 446.9.
(+)-Cloprostenol sodium salt
(+)-Cloprostenol sodium salt is the d-enantiomer of Cloprostenol, which is an aryl-oxymethyl analog of prostaglandin F2&alpha. It has luteolytic effects and is used for the synchronization of estrus in cattle. It is also an FP receptor agonist. Uses: Luteolytic agents. Synonyms: (5Z)-7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-Chlorophenoxy)-3-hydroxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-5-heptenoic Acid Sodium Salt; [1R-[1α(Z), 2β(1E, 3R*), 3α, 5α]]- 7-[2-[4-(3-Chlorophenoxy)-3-hydroxy-1-butenyl]-3,5-dihydroxycyclopentyl]-5-heptenoic Acid Sodium Salt. Grades: 98%. CAS No. 62561-03-9. Molecular formula: C22H28ClO6Na. Mole weight: 446.90.
Closantel Impurity F
N-[5-Chloro-4-(4-chlorobenzoyl)-2-methylphenyl]-2-hydroxy-3,5-diiodo-benzamide is an impurity of Closantel, a broad-spectrum anthelmintic used against nematode infection. Synonyms: N-[5-Chloro-4-(4-chlorobenzoyl)-2-methylphenyl]-2-hydroxy-3,5-diiodo-benzamide. Grades: > 95%. CAS No. 50274-07-2. Molecular formula: C21H13Cl2I2NO3. Mole weight: 652.05.
Clotrimazole Impurity F
1-Tritylimidazole is a Clotrimazole analog as antifungal agent. Synonyms: 1-Tritylimidazole; 1-(Triphenylmethyl)-1H-imidazole; 1-(Triphenylmethyl)imidazole; CDD 3501; N-Tritylimidazole. Grades: > 95%. CAS No. 15469-97-3. Molecular formula: C22H18N2. Mole weight: 310.39.
Cloxacillin EP Impurity D
3-(2-Chlorophenyl)-5-methylisoxazole-4-carboxylic Acid is used in the preparation of isoxazolecarboxamides as a class of TGR5 agonists. It is also used in the preparation of β-lactamase inhibitors. Synonyms: 3-(2-Chlorophenyl)-5-methylisoxazole-4-carboxylic Acid. Grades: > 95%. CAS No. 23598-72-3. Molecular formula: C11H8ClNO3. Mole weight: 237.64.
Cloxacillin Sodium EP Impurity B (Mixture of Diastereomers)
Cloxacillin Sodium EP Impurity B (Mixture of Diastereomers) is a an impurity of Cloxacillin Sodium, an antibiotic medication for treating bacterial infections. Synonyms: 2-[[[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid. Grades: > 95%. CAS No. 1642559-64-5. Molecular formula: C18H19ClN3O4S. Mole weight: 408.89.