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| Product | Description | |
|---|---|---|
| Faropenem Impurity 14 | An impurity of Faropenem. Faropenem is an oral penem, closely related to the carbapenem class that is used for the treatment of bacterial infections. Synonyms: 4-acetyl-2-(4-hydroxybutylidene)-5-methyl-2,5-dihydrothiophene-3-carboxylic acid. Grade: > 95%. Molecular formula: C11H14O4S. Mole weight: 242.30. |  |
| Faropenem Impurity 2 | An impurity of Faropenem. Faropenem is an oral penem, closely related to the carbapenem class that is used for the treatment of bacterial infections. Synonyms: sodium 2-((1R,2R)-1-carboxy-2-hydroxypropyl)-5-((S)-tetrahydrofuran-2-yl)-2,3-dihydrothiazole-4-carboxylate. Grade: > 95%. Molecular formula: C12H16NO6S. Na. Mole weight: 302.33 22.99. | |
| Faropenem Impurity 3 | An impurity of Faropenem. Faropenem is an oral penem, closely related to the carbapenem class that is used for the treatment of bacterial infections. Synonyms: sodium 2-((1R,2R)-1-carboxy-2-hydroxypropyl)-5-((S)-tetrahydrofuran-2-yl)-2,3-dihydrothiazole-4-carboxylate. Grade: > 95%. Molecular formula: C12H16NO6S. Na. Mole weight: 302.33 22.99. | |
| Faropenem Impurity 4 Sodium Salt | An impurity of Faropenem. Faropenem is an oral penem, closely related to the carbapenem class that is used for the treatment of bacterial infections. Synonyms: (5R,?6S)?- 4-Thia-1-azabicyclo[3.2.0]?hept-2-ene-2-carboxylic acid, 6-[(1R)?-1-hydroxyethyl]?-7-oxo-3-[(2R)?-tetrahydro-2-furanyl]?-, Sodium. Grade: > 95%. Molecular formula: C12H14NO6S. Na. Mole weight: 300.31 22.99. | |
| Faropenem Impurity 5 | An impurity of Faropenem. Faropenem is an oral penem, closely related to the carbapenem class that is used for the treatment of bacterial infections. Synonyms: Faropenem dimer impurity. Grade: > 95%. Molecular formula: C24H29N2O11S2. Na. Mole weight: 585.63 22.99. | |
| Faropenem Impurity 6 | An impurity of Faropenem. Faropenem is an oral penem, closely related to the carbapenem class that is used for the treatment of bacterial infections. Synonyms: 4-Thia-1-azabicyclo[3.2.0]?hept-2-ene-2-carboxylic acid, 6-[(1R)?-1-hydroxyethyl]?-7-oxo-3-[(2R)?-tetrahydro-2-furanyl]?-, 2-ethyl ester, (5R,?6S)?-. Grade: > 95%. Molecular formula: C14H19NO5S. Mole weight: 313.38. | |
| Faropenem Impurity 7 | An impurity of Faropenem. Faropenem is an oral penem, closely related to the carbapenem class that is used for the treatment of bacterial infections. Synonyms: 4-Thia-1-azabicyclo[3.2.0]?hept-2-ene-2-carboxylic acid, 6-[1-[[(1,?1-dimethylethyl)?dimethylsilyl]?oxy]?ethyl]?-7-oxo-3-(tetrahydro-2-furanyl)?-, 2-propenyl ester, [5R-[3(S*)?,?5α,?6α(R*)?]?]?- (9CI). Grade: > 95%. CAS No. 120705-68-2. Molecular formula: C21H33NO5SSi. Mole weight: 439.65. | |
| Faropenem Impurity 8 | An impurity of Faropenem. Faropenem is an oral penem, closely related to the carbapenem class that is used for the treatment of bacterial infections. Synonyms: 4-AA Enantiomer. Grade: > 95%. Molecular formula: C13H25NO4Si. Mole weight: 287.43. | |
| Faropenem Impurity 9 | An impurity of Faropenem. Faropenem is an oral penem, closely related to the carbapenem class that is used for the treatment of bacterial infections. Synonyms: sodium (5R,6S)-6-((R)-1-(((R)-3-hydroxybutanoyl)oxy)ethyl)-7-oxo-3-((S)-tetrahydrofuran-2-yl)-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate. Grade: > 95%. Molecular formula: C16H21NO7S. Mole weight: 371.41. | |
| Faropenem Impurity Sodium Salt | An impurity of Faropenem. Faropenem is an oral penem, closely related to the carbapenem class that is used for the treatment of bacterial infections. Synonyms: (5R,?6S)?- 4-Thia-1-azabicyclo[3.2.0]?hept-2-ene-2-carboxylic acid, 6-[(1R)?-1-hydroxyethyl]?-7-oxo-3-[(2S)?-tetrahydro-2-furanyl]?-, sodium salt (1:1)?. Grade: > 95%. CAS No. 195716-77-9. Molecular formula: C12H14NNaO5S. Mole weight: 307.30. | |
| Faropenem potassium | Faropenem potassium is an orally active beta-lactam antibiotic. It is a prodrug of Faropenem and belongs to the penem group. It is resistant to some forms of extended-spectrum beta-lactamase. Synonyms: 4-Thia-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 6-(1-hydroxyethyl)-7-oxo-3-(tetrahydro-2-furanyl)-, monopotassium salt, (5R-(3(R*),5-alpha,6-alpha(R*)))-; Potassium (1'R,2''R,5R,6S)-6-(1'-hydroxyethyl)-2-(2''-tetrahydrofuranyl)-penem-3-carboxylate; (5R,6S)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2S)-oxolan-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate. Grade: >98%. CAS No. 106559-89-1. Molecular formula: C12H14KNO5S. Mole weight: 323.40. | |
| Faropenem Related Compound 1 | An impurity of Faropenem. Faropenem is an oral penem, closely related to the carbapenem class that is used for the treatment of bacterial infections. Synonyms: (2R)?- 2-Furancarbothioic acid, tetrahydro-, S-[(2R,?3S)?-3-[(1R)?-1-[[(1,?1-dimethylethyl)?dimethylsilyl]?oxy]?ethyl]?-4-oxo-2-azetidinyl] ester. Grade: > 95%. CAS No. 106560-32-1. Molecular formula: C16H29NO4SSi. Mole weight: 359.56. | |
| Faropenem Related Compound 2 | An impurity of Faropenem. Faropenem is an oral penem, closely related to the carbapenem class that is used for the treatment of bacterial infections. Synonyms: (3S,?4R)?- 1-Azetidineacetic acid, 3-[(1R)?-1-[[(1,?1-dimethylethyl)?dimethylsilyl]?oxy]?ethyl]?-α,?2-dioxo-4-[[[(2R)?-tetrahydro-2-furanyl]?carbonyl]?thio]?-, 2-propen-1-yl ester. Grade: > 95%. CAS No. 429691-43-0. Molecular formula: C21H33NO7SSi. Mole weight: 471.65. | |
| Faropenem Related Compound 3 | An impurity of Faropenem. Faropenem is an oral penem, closely related to the carbapenem class that is used for the treatment of bacterial infections. Synonyms: (5R,?6S)?- 4-Thia-1-azabicyclo[3.2.0]?hept-2-ene-2-carboxylic acid, 6-[(1R)?-1-[[(1,?1-dimethylethyl)?dimethylsilyl]?oxy]?ethyl]?-7-oxo-3-[(2R)?-tetrahydro-2-furanyl]?-, 2-propen-1-yl ester. Grade: > 95%. CAS No. 120705-67-1. Molecular formula: C21H33NO5SSi. Mole weight: 439.65. | |
| Faropenem Related Compound 4 | An impurity of Faropenem. Faropenem is an oral penem, closely related to the carbapenem class that is used for the treatment of bacterial infections. Synonyms: (5R,?6S)?- 4-Thia-1-azabicyclo[3.2.0]?hept-2-ene-2-carboxylic acid, 6-[(1R)?-1-hydroxyethyl]?-7-oxo-3-[(2R)?-tetrahydro-2-furanyl]?-, 2-propen-1-yl ester. Grade: > 95%. CAS No. 106559-80-2. Molecular formula: C15H19NO5S. Mole weight: 325.39. | |
| Faropenem sodium hydrate (2:2:5) | Faropenem is an orally active beta-lactam antibiotic belonging to the penem group. Synonyms: 4-Thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-tetrahydro-2-furanyl]-, sodium salt, hydrate (2:2:5), (5R,6S)-; 4-Thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-(1-hydroxyethyl)-7-oxo-3-(tetrahydro-2-furanyl)-, monosodium salt, hydrate (2:5), [5R-[3(R*),5α,6α(R*)]]-; 4-Thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-tetrahydro-2-furanyl]-, monosodium salt, hydrate (2:5), (5R,6S)-; Faropenem sodium hemipentahydrate. Grade: 95%. CAS No. 158365-51-6. Molecular formula: C12H14NNaO5S.5/2H2O. Mole weight: 352.35. | |
| Farudodstat | Farudodstat is an orally active and potent inhibitor of DHODH (human dihydroorotate dehydrogenase). It inhibits the proliferation of MOLM-14 and KG-1 acute myeloid leukemia (AML) cells (IC50s = 0.582 and 0.382 μM, respectively), as well as induces apoptosis in the same cells when used at concentrations of 0.5 and 1 μM. Synonyms: 2-[(3,5-difluoro-3'-methoxy-[1,1'-biphenyl]-4-yl)amino]pyridine-3-carboxylic acid; ASLAN003; 2-[(3,5-Difluoro-3'-methoxy-4-biphenylyl)amino]nicotinic Acid; 3-Pyridinecarboxylic acid, 2-[(3,5-difluoro-3'-methoxy-[1,1'-biphenyl]-4-yl)amino]-; 2-((3,5-Difluoro-3'-methoxy-[1,1'-biphenyl]-4-yl)amino)nicotinic acid; 2-[(3,5-difluoro-3'-methoxy[1,1'-biphenyl]-4-yl)amino]-3-pyridinecarboxylic acid. Grade: ≥98%. CAS No. 1035688-66-4. Molecular formula: C19H14F2N2O3. Mole weight: 356.32. | |
| Fascaplysin chloride | Fascaplysin is a cell-permeable red pigment that acts as an inhibitor of cyclin D kinase 4/cyclin D1 (IC50 = 0.35 μM). It is significantly less selective for Cdk6/cyclin D1 (IC50 = 3.4 μM) and does not inhibit other Cdks and tyrosine kinases. Synonyms: NSC 622398. Grade: ≥95%. CAS No. 114719-57-2. Molecular formula: C18H11N2O·Cl. Mole weight: 306.8. | |
| Fas C-Terminal Tripeptide Acetate | Fas C-Terminal Tripeptide Acetate shows inhibitory activity of Fas/FAP-1 binding. Synonyms: Fas C-Terminal Tripeptide Acetate; AKOS040744913. Molecular formula: C18H33N3O8. Mole weight: 419.47. | |
| Fasentin | Fasentin is a GLUT1 and GLUT4 inhibitor (IC50 = 68 μM). Fasentin sensitizes Fas receptor in a range of tumor cell lines (IC50 = 20 μM) via regulating the extrinsic apoptotic pathway downstream of TNF receptors but upstream of effector caspases. Synonyms: N-(4-Chloro-3-(trifluoromethyl)phenyl)-3-oxobutanamide. Grade: ≥98% by HPLC. CAS No. 392721-37-8. Molecular formula: C11H9ClF3NO2. Mole weight: 279.64. | |
| Fasinumab | Fasinumab is a human monoclonal antibody to nerve growth factor (NGF). Fasinumab has been undergoing clinical trials for the treatment of osteoarthritis (OA) hip and/or knee pain. Synonyms: REGN475. CAS No. 1190239-42-9. | |
| Fasitibant chloride hydrochloride | Fasitibant chloride is a selective nonpeptide kinin B2 receptor antagonist. Phase II clinical trials for the treatment of Osteoarthritis were discontinued. Uses: Osteoarthritis. Synonyms: MEN 16132; MEN16132; MEN-16132; (S)-4-amino-5-(4-(4-((2,4-dichloro-3-(((2,4-dimethylquinolin-8-yl)oxy)methyl)phenyl)sulfonamido)tetrahydro-2H-pyran-4-carbonyl)piperazin-1-yl)-N,N,N-trimethyl-5-oxopentan-1-aminium chloride hydrochloride; 1157852-02-2(Fasitibant chloride). Grade: 98%. CAS No. 869880-33-1. Molecular formula: C36H50Cl4N6O6S. Mole weight: 836.71. | |
| Fasnall | Fasnall is an inhibitor of fatty acid synthase (FAS) with an IC50 value of 3.71 μM for the human recombinant enzyme. Synonyms: Fasnall; 929978-58-5; N-(1-benzylpyrrolidin-3-yl)-5,6-dimethylthieno[2,3-d]pyrimidin-4-amine; SCHEMBL21458101; CHEBI:145520; CHEBI:145528; s6248; AKOS007995703; HY-121250; CS-0081306; EN300-14327544; Z31061783; 1-BENZYL-N-{5,6-DIMETHYLTHIENO[2,3-D]PYRIMIDIN-4-YL}PYRROLIDIN-3-AMINE; rac-N-(1-benzylpyrrolidin-3-yl)-5,6-dimethylthieno[2,3-d]pyrimidin-4-amine. CAS No. 929978-58-5. Molecular formula: C19H22N4S. Mole weight: 338.47. | |
| Fasnall benzenesulfonate | Fasnall is an inhibitor of fatty acid synthase (FAS) with an IC50 value of 3.71 μM for the human recombinant enzyme. Synonyms: 5,6-Dimethyl-N-[1-(phenylmethyl)-3-pyrrolidinyl]thieno[2,3-d]pyrimidin-4-amine benzenesulfonate; N-(1-Benzylpyrrolidin-3-yl)-5,6-dimethylthieno[2,3-d] pyrimidin-4-amine benzenesulfonate. Grade: ≥98%. CAS No. 2187367-11-7. Molecular formula: C19H22N4S·C6H6O3S. Mole weight: 496.6. | |
| FASN-IN-4 | FAS-IN-1, a diazaspiro derivative, has been found to be a fatty acid synthase inhibitor that probably have potential biological usage in anticancer study. Uses: Fas-in-1 has been found to be a fatty acid synthase inhibitor that probably have potential biological usage in anticancer study. Synonyms: FAS-IN-1; 1375105-96-6; FASN-IN-4; CHEMBL2147032; 4-cyclopropyl-9-(4-quinolin-7-ylphenyl)sulfonyl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one; SCHEMBL4541971; OGGOWHOQMIINAZ-UHFFFAOYSA-N; BCP28627; BDBM50391837; AKOS030526462; CS-3932; 4-Cyclopropyl-9-((4-(quinolin-7-yl)phenyl)sulfonyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one; NCGC00485940-01; DA-63380; HY-12648; A906146; 4-cyclopropyl-9-{[4-(7-quinolinyl)phenyl]sulfonyl}-1-oxa-4,9-diazaspiro[5.5]undecan-3-one. Grade: 98%. CAS No. 1375105-96-6. Molecular formula: C26H27N3O4S. Mole weight: 477.58. | |
| FASN-IN-4 tosylate | FASN-IN-4 tosylate inhibits SARS-CoV-2 with an EC50 of 18.6?nM. FASN-IN-4 tosylate is a potent inhibitor of fatty acid synthase (FASN) with an IC50 of 10 nM. Grade: 98%. Molecular formula: C33H35N3O7S2. Mole weight: 649.78. | |
| Fasobegron | Fasobegron acts a β3-adrenoreceptor agonist. Synonyms: [1,1'-Biphenyl]-4-carboxylic acid, 4'-[2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]aMino]ethyl]-3-Methoxy-; 4-[4-[2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]ethyl]phenyl]-2-methoxybenzoic acid; (R)-4'-(2-((2-(3-chlorophenyl)-2-hydroxyethyl)amino)ethyl). Grade: 98%. CAS No. 643094-49-9. Molecular formula: C24H24ClNO4. Mole weight: 425.91. | |
| Fasoracetam | Fasoracetam is a GABA receptor modulator potentially for the treatment of attention deficit hyperactivity disorder. Synonyms: (5R)-5-(piperidine-1-carbonyl)-2-pyrrolidone; (5R)-5-piperidin-1-ylcarbonylpyrrolidin-2-one. CAS No. 110958-19-5. Molecular formula: C10H16N2O2. Mole weight: 196.248. | |
| Fasudil | Fasudil is a potent and selective Rho-kinase (ROCK) inhibitor and vasodilator. ROCK is an enzyme that participates in vasoconstriction and vascular remodeling. Fasudil is used for the treatment of cerebral vasospasm and has the potential to treat pulmonary hypertension as well as certain memory loss. Uses: Protein kinase inhibitors. Synonyms: Fasudil; AT 877; AT-877; AT877; HA 1077; HA-1077; HA1077; 5-(1,4-diazepan-1-ylsulfonyl)isoquinoline. Grade: >98%. CAS No. 103745-39-7. Molecular formula: C14H17N3O2S. Mole weight: 291.369. | |
| Fasudil Dimer | A dimer impurity of Fasudil. Fasudil is Ccyclic nucleotide-dependent protein kinase inhibitor and Rho-associated kinase inhibitor. Synonyms: 5,?5'-[(tetrahydro-1H-1,?4-diazepine-1,?4(5H)?-diyl)?bis(sulfonyl)?]?bis- Isoquinoline. Grade: > 95%. CAS No. 1337967-93-7. Molecular formula: C23H22N4O4S2. Mole weight: 482.58. | |
| Fasudil hydrochloride | Fasudil HCl, a 5-isoquinolinesulfonamide derivative, is a highly selective Rho-associated protein kinase inhibitor that might have a rate in romoting the recovery of neurological function, reducing clinical symptoms and the morbidity. Uses: Fasudil hcl, a 5-isoquinolinesulfonamide derivative, is a highly selective rho-associated protein kinase inhibitor that might have a rate in romoting the recovery of neurological function, reducing clinical symptoms and the morbidity. Synonyms: Fasudil HCl; Eril; Fasudil (Hydrochloride); Fasudil Monohydrochloride; AT-877; HA-1077; AT 877; HA 1077; AT877; HA1077. Grade: >98%. CAS No. 105628-07-7. Molecular formula: C14H18ClN3O2S. Mole weight: 327.83. | |
| Fasudil Impurity 1 | An impurity of Fasudil. Fasudil is Ccyclic nucleotide-dependent protein kinase inhibitor and Rho-associated kinase inhibitor. Synonyms: 8-[(hexahydro-1H-1,?4-diazepin-1-yl)?sulfonyl]?- Quinoline. Grade: > 95%. CAS No. 1423155-03-6. Molecular formula: C14H17N3O2S. Mole weight: 291.37. | |
| Fasudil Impurity 2 | An impurity of Fasudil. Fasudil is Ccyclic nucleotide-dependent protein kinase inhibitor and Rho-associated kinase inhibitor. Synonyms: Isoquinoline-8-sulfonic acid. Grade: > 95%. Molecular formula: C9H7NO3S. Mole weight: 209.23. | |
| Fasudil Impurity 3 | An impurity of Fasudil. Fasudil is Ccyclic nucleotide-dependent protein kinase inhibitor and Rho-associated kinase inhibitor. Synonyms: Isoquinoline, 8-[(hexahydro-1H-1,?4-diazepin-1-yl)?sulfonyl]?-, hydrochloride. Grade: > 95%. CAS No. 166895-80-3. Molecular formula: C14H17N3O2S. HCl. Mole weight: 291.37 36.46. | |
| Fasudil N-Hydroxy Impurity | An impurity of Fasudil. Fasudil is Ccyclic nucleotide-dependent protein kinase inhibitor and Rho-associated kinase inhibitor. Synonyms: 5-[(hexahydro-4-hydroxy-1H-1,?4-diazepin-1-yl)?sulfonyl]?- Isoquinoline. Grade: > 95%. CAS No. 1350827-92-7. Molecular formula: C14H17N3O3S. Mole weight: 307.37. | |
| Fasudil Pyridine N-Oxide | An impurity of Fasudil. Fasudil is Ccyclic nucleotide-dependent protein kinase inhibitor and Rho-associated kinase inhibitor. Synonyms: Isoquinoline, 5-[(hexahydro-1H-1,?4-diazepin-1-yl)?sulfonyl]?-, 2-oxide. Grade: > 95%. CAS No. 186544-56-9. Molecular formula: C14H17N3O3S. Mole weight: 307.37. | |
| Fatostatin A | Fatostatin (125B11) is an inhibitor of SREBP activation and prevents SCAP-mediated escort of SREBP-1 or SREBP-2 to the Golgi (IC50 = 5.6 μM). Fatostatin has anti-tumor properties and can reduce hyperglycemia in ob/ob mice. Synonyms: Fatostatin; 4-(4-Methylphenyl)-2-(2-Propyl-4-Pyridinyl)Thiazole; 125B11. Grade: 98%. CAS No. 125256-00-0. Molecular formula: C18H18N2S. Mole weight: 294.4. | |
| Fatostatin A hydrobromide | Fatostatin A is an inhibitor of sterol regulatory element binding protein (SREBP). Fatostatin A reverses hyperglycemia in diabetic (ob/ob) mice, and inhibits proliferation in DU 145 cells independently of IGF-1 signaling (IC50 = 0.1 μM). Uses: The treatment of some metabolic disorders. Synonyms: Fatostatin A; 4-[4-(4-Methylphenyl)-2-thiazolyl]-2-propylpyridine hydrobromide; 2-Propyl-4-(4-p-tolyl-thiazol-2-yl)-pyridine. Grade: ≥97% by HPLC. CAS No. 298197-04-3. Molecular formula: C18H18N2S.HBr. Mole weight: 375.33. | |
| FAUC-365 | FAUC-365 is a selective antagonist of dopamine D3 receptor with a Ki of 0.5 nM over dopamine D1/D2L/D2S/D4 receptors (Kis = 8.8, 3.6, 2.6, and 0.34 μM, respectively) as well as 5-HT1A and 5-HT2 (Kis = 0.36 and 2 μM, respectively). Uses: Dopamine antagonists. Synonyms: N-[4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butyl]-benzo[b]thiophene-2-carboxamide. Grade: ≥98%. CAS No. 474432-66-1. Molecular formula: C23H25Cl2N3OS. Mole weight: 462.4. | |
| Favipiravir | Favipiravir, also known as T-705 or Avigan, is an experimental antiviral drug being developed by Toyama Chemical of Japan with activity against many RNA viruses. Like some other experimental antiviral drugs (T-1105 and T-1106), it is a pyrazinecarboxamide derivative. Favipiravir is active against influenza viruses, West Nile virus, yellow fever virus, foot-and-mouth disease virus as well as other flaviviruses, arenaviruses, bunyaviruses and alphaviruses. Activity against enteroviruses and Rift Valley fever virus has also been demonstrated. Synonyms: T-705; avigan; 6-Fluoro-3-hydroxypyrazine-2-carboxamide. Grade: ≥97%. CAS No. 259793-96-9. Molecular formula: C5H4FN3O2. Mole weight: 157.10. | |
| Faxeladol | Faxeladol is an opioid analgesic with a higher rate of sudden seizures than tramadol. Uses: An opioid analgesic. Synonyms: GCR9905; GCR 9905; GCR-9905; EM-906; EM 906; EM906; GRT-TA300; GRTA9906; GRTA-9906; GRTA 9906; GRTA0009906; GRTA-0009906; GRTA 0009906; Faxeladol3-((1R,2R)-2-((dimethylamino)methyl)cyclohexyl)phenol. Grade: ≥95%. CAS No. 433265-65-7. Molecular formula: C15H23NO. Mole weight: 233.36. | |
| Fazarabine | Fazarabine, also known as Kymarabine, is an orally-active pyrimidine analogue of an aza-substituted cytidine in which the ribose moiety is replaced by an arabinose sugar. Similar in action to cytarabine, fazarabine is phosphorylated by deoxycytidine kinase to a triphosphate form which competes with thymidine for incorporation into DNA; its incorporation into DNA inhibits DNA synthesis, resulting in tumor cell death and tumor necrosis. The presence of deoxycytidine kinase in a tumor is a determinant of tumor sensitivity to this drug. Synonyms: CCRIS 93; CCRIS-93; CCRIS93; NSC 281272; NSC-281272; NSC281272; Ara-AC; 5-Azacytosine arabinoside; 1-beta-D-Arabinofuranosyl-5-azacytosine. CAS No. 65886-71-7. Molecular formula: C8H12N4O5. Mole weight: 244.20. | |
| FB23 | FB23 is a potent and selective FTO demethylase inhibitor with IC50 of 60 nM. FB23 directly binds to FTO and selectively inhibits FTO's m6A demethylase activity. Synonyms: 2-((2,6-Dichloro-4-(3,5-dimethylisoxazol-4-yl)phenyl)amino)benzoic acid. Grade: 98%. CAS No. 2243736-35-6. Molecular formula: C18H14Cl2N2O3. Mole weight: 377.22. | |
| FB23-2 | FB23-2 is a potent and selective demethylase inhibitor with IC50 of 2.6 μM. FB23-2 directly binds to FTO and selectively inhibits FTO's m6A demethylase activity. CAS No. 2243736-45-8. Molecular formula: C18H15Cl2N3O3. Mole weight: 392.24. | |
| FC131 TFA | FC131 TFA is a CXCR4 antagonist with anti-HIV activity. Synonyms: FC 131 TFA; FC-131 TFA. Molecular formula: C38H48F3N11O8. Mole weight: 843.85. | |
| Fc1-dUTP | Fc1-dUTP, a ferrocene-labelled analogue, is efficiently incorporated into DNA during synthesis, including incorporation of two successive modified nucleotides. Fc1-dUTP is also a satisfactory substrate for PCR. Synonyms: 5-(3-ferrocenecarboxamidopropenyl-1) 2'-deoxyuridine 5'-triphosphate. | |
| FC 99 hydrochloride | FC 99 hydrochloride is an inhibitor of TLR3 expression and suppresses inflammatory responses induced by a synthetic dsRNA (poly(I:C)) and by exogenous IFN-α via IRF3. It inhibits the phosphorylation levels of ERK, JNK, and p38 in varying degrees without altering the total protein. Synonyms: FC 99 hydrochloride; FC99 hydrochloride; FC-99 hydrochloride. Grade: 98%. CAS No. 2734014-73-2. Molecular formula: C15H18N2O.xHCl. Mole weight: 242.32 (free base). | |
| FCCP | As A very potent uncoupler of oxidative phosphorylation in mitochondria, FCCP transports protons across cell membranes which disrupts ATP synthesis. Uses: A very potent uncoupler of oxidative phosphorylation in mitochondria. Synonyms: 2-[[4-(trifluoromethoxy)phenyl]hydrazinylidene]propanedinitrile. Grade: ≥98%. CAS No. 370-86-5. Molecular formula: C10H5F3N4O. Mole weight: 254.17. | |
| FCE 26644 | FCE 26644, also known as PNU-145156E, has been found to be a angiogenesis inhibitor that could have probable effect against solid tumours. It has already been discontined. Synonyms: PNU-145156E; PNU145156E; PNU 145156E; FCE26644; FCE-26644; FCE 26644. 7,7'-(Carbonyl-bis(imino-N-methyl-4,2-pyrrolcarbonylimino(N-methyl-4,2-pyrrol)carbonylimino))-bis(1,3-naphthalenedisulfonic acid); 1,3-Naphthalenedisulfonic acid, 7,7'-(carbonylbis(imino(1-methyl-1H-pyrrole-4,2-diyl)carb. Grade: 98%. CAS No. 154788-16-6. Molecular formula: C45H36N10Na4O17S4. Mole weight: 1209.04. | |
| FD 12-9 | FD 12-9 is a dual inhibitor of P-gp and BCRP, with EC50s of 285 nM and 0.9 nM, respectively. It has anti-glioblastoma activity. Synonyms: Ac12Az9. CAS No. 1451741-22-2. Molecular formula: C51H47N3O11. Mole weight: 877.93. | |
| FD223 | FD223 is a potent and selective PI3Kδ inhibitor that displays high potency (IC50 = 1 nM) and good selectivity over other isoforms (IC50s of 51 nM, 29 nM and 37 nM, respectively for α, β and γ). FD223 has potential for the research of leukemia such as AML. Grade: 98%. CAS No. 2050524-24-6. Molecular formula: C17H12ClN5O2S. Mole weight: 385.83. | |
| FDI 6 | FDI 6 is an inhibitor of the Forkhead box protein M1 transcription factor (FOXM1) (IC50 value 22.5 μM) that suppresses FOXM1 binding to DNA. FDI6 displaces ?FOXM1 from genomic targets in MCF-7 breast cancer cells, and downregulates concomitant transcription. Synonyms: FDI-6; FDI 6; FDI6; NCGC00099374; NCGC-00099374; NCGC 00099374; 3-amino-6-thiophen-2-yl-4-trifluoromethyl-thieno[2,3-b]pyridine-2-carboxylic acid (4-fluoro-phenyl)-amide; 3-amino-N-(4-fluorophenyl)-6-(2-thienyl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide; 3-amino-N-(4-fluorophenyl)-6-(thiophen-2-yl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide; AC1NPA9B. Grade: 99%. CAS No. 313380-27-7. Molecular formula: C19H11F4N3OS2. Mole weight: 437.43. | |
| FD-IN-1 | FD-IN-1 is an orally bioavailable and selective inhibitor of factor D (FD) with an IC50 of 12 nM. It also inhibits factor XIa (FXIa) and Tryptase β2 with IC50s of 7.7 and 6.5 μM, respectively. Complement FD is a highly specific S1 serine protease that plays a central role in the alternative complement pathway of the innate immune system. Synonyms: Benzeneacetic acid, 2-[[3'-[(1S)-1-amino-2-hydroxyethyl][1,1'-biphenyl]-3-yl]methoxy]-; (S)-2-(2-((3'-(1-amino-2-hydroxyethyl)-[1,1'-biphenyl]-3-yl)methoxy)phenyl)acetic acid; [2-({3'-[(1S)-1-Amino-2-hydroxyethyl]-3-biphenylyl}methoxy)phenyl]acetic acid. Grade: ≥95%. CAS No. 1646682-14-5. Molecular formula: C23H23NO4. Mole weight: 377.43. | |
| FDL169 | FDL169 is a CFTR corrector (cystic fibrosis transmembrane conductance corrector) that is extracted from patent US20140274933. FDL169 is designed to fix and restore the function of the defective CFTR protein. Synonyms: CFTR corrector 2. Grade: ≥98%. CAS No. 1628416-28-3. Molecular formula: C27H23FN4O4. Mole weight: 486.49. | |
| FDMT-N2-iBu-dG CEP | FDMT-N2-iBu-dG CEP, an indispensable asset within the biomedical field, stands at the forefront of research endeavors. As a derivative nucleoside analogue, it houses the quintessential CEP (Cytidine 5'-O-(1,2-dihydroxypropyl) phosphoramidite) moiety. CAS No. 865758-46-9. Molecular formula: C54H57F17N7O8P. Mole weight: 1286.02. | |
| FDMT-N4-Bz-dC CEP | FDMT-N4-Bz-dC CEP, a compound of utmost importance in the field of biomedicine, finds extensive utilization. This product occupies a momentous position in biomedical investigation and pharmaceutical progress, particularly in the remedy of diverse ailments. Its capacity to provide therapy is directed towards tackling selected intractable cancers and viral infections. CAS No. 865758-45-8. Molecular formula: C56H55F17N5O8P. Mole weight: 1280.01. | |
| FDMT-N6-Bz-dA CEP | FDMT-N6-Bz-dA CEP is an indispensable constituent within the biomedical sector, emerging as an instrumental substance in the synthesis of oligonucleotides, thereby catalyzing the realms of DNA/RNA exploration. Synonyms: 5'-O-FDMT-N6-BENZOYL-2'-DEOXYADENOSINE CEP; 3'-O-[(Diisopropylamino)(2-cyanoethoxy)phosphino]-5'-O-[4,4'-dimethoxy-4''-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl)trityl]-N-benzoyl-2'-deoxyadenosine. Grade: 95%. CAS No. 865758-44-7. Molecular formula: C57H55F17N7O7P. Mole weight: 1304.04. | |
| FDMT-T CEP | FDMT-T CEP is an extraordinary biomedical compound used for cancer research. It can deter tumor cells growth while orchestrating the demise of malignant cells through programmed cell death induction. Synonyms: Thymidine, 5'-O-[[4-(1H,1H,2H,2H-perfluorodecyl)phenyl]bis(4-methoxyphenyl)methyl]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 5'-O-FDMT-THYMIDINE CEP. Grade: 95%. CAS No. 902456-09-1. Molecular formula: C50H52F17N4O8P. Mole weight: 1190.92. | |
| FdUTP | FdUTP, a remarkable nucleoside triphosphate, puts the brakes on thymidylate synthase, striking a fatal blow to DNA precursor synthesis and culminating in cellular collapse. This versatile substance has proven tadpole in tackling a gamut of solid tumors, from the grisly colorectal specter to the dauntingly defiant breast cancer. Synonyms: 5-Fluoro-2'-deoxyuridine-5'-triphosphate. Grade: ≥ 95 % (HPLC). Molecular formula: C9H14N2O14P3F (free acid). Mole weight: 486.1 (free acid). | |
| FE-999024 | FE-999024, a dipeptide compound, has been found to be a kallikrein inhibitor that was once studied in pancreatitis by Ferring Pharmaceuticals. Synonyms: FE-999024; FE 999024; FE999024; CH-2856; CH2856; CH 2856; L-Alaninamide, 4-chloro-D-phenylalanyl-N-(3-((aminoiminomethyl)amino)propyl)-3-(1-naphthalenyl)-. Grade: 98%. CAS No. 168825-65-8. Molecular formula: C26H31ClN6O2. Mole weight: 495.02. | |
| Febantel | Febantel is an anthelmintic for veterinary use on dogs, cats, cattle, sheep, goats, pig and poultry against roundworms and tapeworms, which is a veteran anthelmintic compound belonging to the chemical class of the benzimidazoles. It is transformed into fenbendazole in the stomach and the intestine of the host, shortly after ingestion. Synonyms: Febantel; Rintal; Bay Vh 5757; Febantelum [INN-Latin]; BAY Vh5757; Febantelum; Combotel; Oratel; Negabot Plus; Paste; Rintal (TN); Febantel (USAN/INN). Grade: >98%. CAS No. 58306-30-2. Molecular formula: C20H22N4O6S. Mole weight: 446.48. | |
| Febuxostat 2-Butyl Isomer Ethyl Ester | Febuxostat 2-Butyl Isomer Ethyl Ester is an impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Synonyms: Ethyl 2-(4-(sec-Butoxy)-3-cyanophenyl)-4-methylthiazole-5-carboxylate. CAS No. 2375033-35-3. Molecular formula: C18H20N2O3S. Mole weight: 344.43. | |
| Febuxostat Acyl Glucuronide | An impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Synonyms: Febuxostat Acyl-β-D-glucuronide. Grade: > 95%. CAS No. 1351692-92-6. Molecular formula: C22H24N2O9S. Mole weight: 492.50. | |
| Febuxostat Amide Impurity | An impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Synonyms: 2-[3-(Aminocarbonyl)-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic acid. Grade: >95%. CAS No. 1239233-86-3. Molecular formula: C16H18N2O4S. Mole weight: 334.40. | |
| Febuxostat Impurity 10 | An impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Synonyms: 2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid 1-oxide. Grade: > 95%. Molecular formula: C16H16N2O4S. Mole weight: 332.38. | |
| Febuxostat Impurity 11 | An impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Synonyms: 4-Nitrophthalonitrile. Grade: > 95%. CAS No. 31643-49-9. Molecular formula: C8H3N3O2. Mole weight: 173.13. | |
| Febuxostat Impurity 12 | An impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Synonyms: 2-nitrobenzene-1,3,5-tricarbonitrile. Grade: > 95%. Molecular formula: C9H2N4O2. Mole weight: 198.14. | |
| Febuxostat Impurity 13 | An impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Synonyms: Dimer of 5Z-[(2E)-2-methyl-3-phenyl-2-propen-1-ylidene]-4-oxo-2-thioxo-3-thiazolidineacetic acid. Grade: > 95%. Molecular formula: C32H36N4O6S2. Mole weight: 636.79. | |
| Febuxostat Impurity 14 | An impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Synonyms: 2-(2-methylpropoxy)?-5-(4-methyl-2-thiazolyl)?- Benzonitrile. Grade: > 95%. CAS No. 1335202-60-2. Molecular formula: C15H16N2OS. Mole weight: 272.37. | |
| Febuxostat Impurity 15 | An impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Synonyms: 2-(4-butoxy-3-cyanophenyl)thiazole-5-carboxylic acid. Grade: > 95%. Molecular formula: C15H14N2O3S. Mole weight: 302.35. | |
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