BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Finerenone | Finerenone is a non-steroidal antimineralocorticoid. It has less relative affinity to other steroid hormone receptors than currently available, which should result in fewer adverse effects like impotence, gynaecomastia and low sex drive. It was developed by BAyer. It is in phase III clinical trials for the treatment of chronic heart failure, chronic kidney disease and diabetic nephropathy. Uses: Finerenone was used for the treatment of chronic heart failure, chronic kidney disease and diabetic nephropathy. Synonyms: BAY94-8862; BAY-94-8862; BAY948862; BAY-948862; Kerendia; (S)-4-(4-Cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide. Grade: 98%. CAS No. 1050477-31-0. Molecular formula: C21H22N4O3. Mole weight: 378.43. |  |
| Fingolimod Dimer Impurity | An impurity of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: N-[2(4-(-Octylphenyl))butanoic Acid] Fingolimod; 2-((1-Hydroxy-2-(hydroxymethyl)-4-(4-octylphenyl)butan-2-yl)amino)-4-(4-octylphenyl)butanoic Acid. Grade: > 95%. Molecular formula: C37H59NO4. Mole weight: 581.89. | |
| Fingolimod EP Impurity A | An impurity of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: Des(octyl)hexyl fingolimod; Fingolimod hexyl homolog. Grade: > 95%. CAS No. 1201794-93-5. Molecular formula: C17H29NO2. Mole weight: 279.43. | |
| Fingolimod EP Impurity B | An impurity of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: 2-amino-2-[2-(4-heptylphenyl)?ethyl]?-1,?3-Propanediol; Fingolimod heptyl homolog; Des(octyl)heptyl fingolimod. Grade: > 95%. CAS No. 745767-97-9. Molecular formula: C18H31NO2. Mole weight: 293.45. | |
| Fingolimod EP Impurity C | Fingolimod EP Impurity C is an impurity of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: Fingolimod nonyl homolog; Des(octyl)nonyl fingolimod. CAS No. 746594-44-5. Molecular formula: C20H35NO2. Mole weight: 321.51. | |
| Fingolimod EP Impurity D | Fingolimod EP Impurity D is an impurity of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: Fingolimod decyl homolog; Des(octyl)decyl fingolimod. CAS No. 780729-32-0. Molecular formula: C21H37NO2. Mole weight: 335.53. | |
| Fingolimod EP Impurity E | Fingolimod EP Impurity E is an impurity of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: 2-(4-Octylphenethyl)-fingolimod; 2-Amino-2-(4-octyl-2-(4-octylphenethyl)phenethyl)propane-1,3-diol; 2-Phenethyl fingolimod analog. CAS No. 851039-25-3. Molecular formula: C35H57NO2. Mole weight: 523.85. | |
| Fingolimod EP Impurity F | Fingolimod EP Impurity F is an impurity of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: 3-(4-Octylphenethyl)-fingolimod; 2-Amino-2-(4-octyl-3-(4-octylphenethyl)phenethyl)propane-1,3-diol; 3-Phenethyl fingolimod analog. CAS No. 851039-24-2. Molecular formula: C35H57NO2. Mole weight: 523.85. | |
| Fingolimod EP Impurity G | Fingolimod EP Impurity G is an impurity of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: 2-Amino-2-(hydroxymethyl)-4-(4-octylphenyl)butyl acetate. CAS No. 1807973-92-7. Molecular formula: C21H35NO3. Mole weight: 349.52. | |
| Fingolimod EP Impurity I | An intermediate in the synthesis of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: N-[1,?1-bis(hydroxymethyl)?-3-(4-octylphenyl)?propyl]?-Acetamide. Grade: > 95%. CAS No. 249289-10-9. Molecular formula: C21H35NO3. Mole weight: 349.52. | |
| Fingolimod Impurity 1 | An impurity of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: Deshydroxymethyl Carboxyethyl N,O-Diacetyl Fingolimod; Ethyl 2-Acetamido-2-(acetoxymethyl)-4-(4-octylphenyl)butanoate. Grade: > 95%. Molecular formula: C25H39NO5. Mole weight: 433.59. | |
| Fingolimod Impurity 10 | An impurity of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: 1-(1-iodoethyl)-4-octylbenzene. Grade: > 95%. Molecular formula: C16H25I. Mole weight: 344.28. | |
| Fingolimod Impurity 11 | An impurity of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: 2-Amino-2-[2-(4-pentylphenyl)?ethyl]?-1,?3-propanediol Hydrochloride. Grade: > 95%. Molecular formula: C16H27NO2 HCl. Mole weight: 265.40 36.46. | |
| Fingolimod Impurity 12 | An impurity of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: β-amino-4-octyl- Benzenebutanol. Grade: > 95%. CAS No. 177260-59-2. Molecular formula: C18H31NO. HCl. Mole weight: 277.45 36.46. | |
| Fingolimod Impurity 13 | An impurity of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: Benzenebutanoic acid, α-amino-α-(hydroxymethyl)?-4-octyl-, ethyl ester. Grade: > 95%. CAS No. 882691-14-7. Molecular formula: C21H35NO3. Mole weight: 349.51. | |
| Fingolimod Impurity 14 | An impurity of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: 3-amino-3-(hydroxymethyl)?-1-(4-octylphenyl)?- 1,?4-Butanediol. Grade: > 95%. CAS No. 162361-49-1. Molecular formula: C19H33NO3. Mole weight: 323.48. | |
| Fingolimod Impurity 4 | An impurity of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: N-Acetyl Deshydroxymethyl Fingolimod; Fingolimod Impurity; N-[1-(hydroxymethyl)-3-(4-octylphenyl)propyl]acetamide. Grade: > 95%. CAS No. 177259-52-8. Molecular formula: C20H33NO2. Mole weight: 319.49. | |
| Fingolimod Impurity 5 | An impurity of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: anedioic acid, 2-(acetylamino)?-2-[2-(4-octylphenyl)?-2-oxoethyl]?-, 1,?3-diethyl ester. Grade: > 95%. CAS No. 268557-49-9. Molecular formula: C25H37NO6. Mole weight: 447.58. | |
| Fingolimod Impurity 7 | An impurity of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: 2-Nitrodeamino Fingolimod; 2-Nitro-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol. Grade: > 95%. CAS No. 374077-88-0. Molecular formula: C19H31NO4. Mole weight: 337.46. | |
| Fingolimod Impurity 8 | An impurity of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: 1-(2-Iodoethyl)?-2-octylbenzene. Grade: > 95%. CAS No. 162358-96-5. Molecular formula: C16H25I. Mole weight: 344.28. | |
| Fingolimod Impurity 9 | An impurity of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: ortho-Fingolimod; 2-Amino-2-(2-octylphenethyl)propane-1,3-diol. Grade: > 95%. CAS No. 767262-51-1. Molecular formula: C19H33NO2. Mole weight: 307.48. | |
| Fingolimod Methyl Impurity | An impurity of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: 2-(methylamino)?-2-[2-(4-octylphenyl)?ethyl]?-1,?3-Propanediol. Grade: > 95%. CAS No. 162361-47-9. Molecular formula: C20H35NO2. Mole weight: 321.51. | |
| Fingolimod Palmitate Amide | An impurity of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: N-(1-Hydroxy-2-(hydroxymethyl)-4-(4-octylphenyl)butan-2-yl)palmitamide. Grade: > 95%. CAS No. 1242271-26-6. Molecular formula: C35H63NO3. Mole weight: 545.90. | |
| Fingolimod Phosphate HCl | A phosphate derivative of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: rac FTY720 Phosphate; 1,?3-Propanediol, 2-amino-2-[2-(4-octylphenyl)?ethyl]?-, 1-(dihydrogen phosphate) hydrochloride; 2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol 1-(Dihydrogen Phosphate). Grade: > 95%. CAS No. 1348803-59-7. Molecular formula: C19H34NO5P. HCl. Mole weight: 387.46 36.46. | |
| Fingolimod Stearate Amide | An impurity of Fingolimod. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. Synonyms: N-(1-Hydroxy-2-(hydroxymethyl)-4-(4-octylphenyl)butan-2-yl)stearamide. Grade: > 95%. CAS No. 1242271-27-7. Molecular formula: C37H67NO3. Mole weight: 573.95. | |
| FINO2 | FINO2 is a ferroptosis-inducing peroxide compound that indirectly inhibits glutathione peroxidase 4 (GPX4) and oxidizes iron. FINO2 is a stable oxidant that oxidizes ferrous iron and stable at varying pH levels. Synonyms: 2-[(5s,8s)-8-tert-butyl-3-methyl-1,2-dioxaspiro[4.5]decan-3-yl]ethan-1-ol. CAS No. 869298-31-7. Molecular formula: C15H28O3. Mole weight: 256.38. | |
| Finrozole | Finrozole is an aromatase (CYP19A1) inhibitor. Synonyms: Finrozole; Finrozole [INN]; MPV-2213ad; 160146-17-8; UNII-40028KHQ6B; 40028KHQ6B; 4-[(1R,2S)-3-(4-fluorophenyl)-2-hydroxy-1-(1,2,4-triazol-1-yl)propyl]benzonitrile; p-((1RS,2SR)-3-(p-Fluorophenyl)-2-hydroxy-1-(1H-1,2,4-triazol-1-yl)propyl)benzonitrile; Benzonitrile, 4-(3-(4-fluorophenyl)-2-hydroxy-1-(1H-1,2,4-triazol-1- yl)propyl)-, (R*,S*)-(+-)-; SCHEMBL2138489; DTXSID90166806; AKOS040748353; Q15633964; BENZONITRILE, 4-((1R,2S)-3-(4-FLUOROPHENYL)-2-HYDROXY-1-(1H-1,2,4-TRIAZOL-1-YL)PROPYL)-, REL-. Grade: 95%. CAS No. 160146-17-8. Molecular formula: C18H15FN4O. Mole weight: 322.34485. | |
| Fipexide | Fipexide hydrochloride is a nootropic agent that displays a positive effect on cognitive function. Uses: A nootropic drug, mainly for the treatment of senile dementia. Synonyms: 1-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]-2-(4-chlorophenoxy)ethanone. Grade: ≥98%. CAS No. 34161-24-5. Molecular formula: C20H21ClN2O4. Mole weight: 388.85. | |
| Fipexide hydrochloride | Fipexide is a nootropic drug of the piperazine chemical class. It displays a positive effect on cognitive function. Synonyms: Attentil. CAS No. 34161-23-4. Molecular formula: C20H21ClN2O4.HCl. Mole weight: 425.31. | |
| FIPI | FIPI, a derivative of halopemide, is a potent and selective phospholipase D (PLD) inhibitor with IC50 values of 20 and 25 nM for PLD2 and PLD1 respectively. It attenuate mercury-induced lipid signaling leading to protection against cytotoxicity in aortic endothelial cells. It rapidly blocks in vivo PA production with subnanomolar potency. It has good pharmacokinetic parameters in rats. It did not significantly inhibit p38 or ERK phosphorylation in bone marrow-derived macrophages stimulated with lipopolysaccharide. It prevents PLD regulation of F-actin cytoskeleton reorganization, cell spreading, and chemotaxis. Synonyms: 5-Fluoro-2-Indolyl des-Chlorohalopemide; N-[2-[4-(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]ethyl]-5-fluoro-1H-indole-2-carboxamide; 5-Fluoro-N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)-1H-indole-2-carboxamide. Grade: >98 %. CAS No. 939055-18-2. Molecular formula: C23H24FN5O2. Mole weight: 421.47. | |
| FIPI hydrochloride | FIPI hydrochloride is an inhibitor of phospholipase D (PLD) (IC50 values of 20-25 nM for both PLD1 and PLD2), which is an enzyme catalyzing the hydrolysis of phosphatidylcholine to form phosphatidic acid. FIPI blocks in vivo phosphatidic acid (PA) production with subnanomolar potency. FIPI is a candidate therapeutic for autoimmunity and cancer metastasis. Uses: Potential treatment of autoimmunity and cancer metastasis. Synonyms: AOB33782; AKOS024457709; N-[2-[4-(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]ethy]-5-fluoro-1H-indole-2-carboxamide hydrochloride; 5-fluoro-N-[2-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]ethyl]-1H-indole-2-carboxamide hydrochloride. Grade: 99%. CAS No. 1781834-93-2. Molecular formula: C23H24FN5O2.HCl. Mole weight: 457.93. | |
| Fipronil carboxamide | Fipronil carboxamide is an impurity of Fipronil. Fipronil is a broad-spectrum insecticide that disrupts the insect central nervous system by blocking GABA-gated chloride channels and glutamate-gated chloride channels, resulting in central nervous system toxicity. Synonyms: 5-Amino-1-(2,6-dichloro-4-trifluoromethyl phenyl)-4-trifluoromethane-sulfinyl-1H-pyrazole-3-carboxylic acid amide. CAS No. 205650-69-7. Molecular formula: C12H6Cl2F6N4O2S. Mole weight: 455.156. | |
| Fipronil Desulfinyl | Fipronil Desulfinyl is a photodegradation product of Fipronil. Fipronil is a broad-spectrum insecticide. Synonyms: 5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethyl)-1H-pyrazole-3-carbonitrile; Desulfinylfipronil. Grade: > 95%. CAS No. 205650-65-3. Molecular formula: C12H4Cl2F6N4. Mole weight: 389.09. | |
| Fipronil Impurity 1 | An impurity of Fipronil. Fipronil is a broad-spectrum insecticide. Synonyms: 1-(2,6-Dichloro-4-trifluoromethylphenyl)-3-carboxamido-5-aminopyrazole; 5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-1H-Pyrazole-3-carboxamide. Grade: > 95%. CAS No. 270564-31-3. Molecular formula: C11H7Cl2F3N4O. Mole weight: 339.11. | |
| Fipronil Impurity 2 | An impurity of Fipronil. Fipronil is a broad-spectrum insecticide. Synonyms: 5-Amino-1-[2-chloro-4-(trifluoromethyl)phenyl]-1H-pyrazole-3-carbonitrile. Grade: > 95%. CAS No. 120068-81-7. Molecular formula: C11H6ClF3N4. Mole weight: 286.65. | |
| Fipronil-[pyrazole-13C3,cyano-13C] | Labelled Fipronil. Fipronil is a broad-spectrum insecticide that disrupts the insect central nervous system by blocking GABA-gated chloride channels and glutamate-gated chloride channels, resulting in central nervous system toxicity. Synonyms: 5-Amino-3-cyano-13C-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfinyl]pyrazole-13C3. Grade: 98% by HPLC. CAS No. 2140327-54-2. Molecular formula: C8[13C]4H4Cl2F6N4OS. Mole weight: 441.12. | |
| Fipronil Sulfide | Fipronil Sulfide is a degradation product of the insecticide Fipronil. Fipronil is a broad-spectrum insecticide. Synonyms: 1-(2,6-Dichloro-4-trifluoromethylphenyl)-3-cyano-5-amino-4-(trifluoromethylthio)pyrazole; 5-Amino-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-trifluoromethylthio-1H-pyrazole- 3-carbonitrile. Grade: > 95%. CAS No. 120067-83-6. Molecular formula: C12H4Cl2F6N4S. Mole weight: 421.15. | |
| Fipronil Sulfone | Fipronil Sulfone is a sulfone metabolite of the insecticide Fipronil. Fipronil is a broad-spectrum insecticide. Uses: Insecticides. Synonyms: 5-Amino-1-(2,6-dichloro-4-trifluoromethylphenyl)-3-cyano-4-trifluoromethylsulfonylpyrazole; 5-Amino-1-[2,6-Dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfonyl)pyrazole-3-carbonitrile. Grade: > 95%. CAS No. 120068-36-2. Molecular formula: C12H4Cl2F6N4O2S. Mole weight: 453.15. | |
| Firategrast | Firategrast is an orally bioavailable alpha4 beta1/alpha4 beta7 integrin antagonist designed to reduce trafficking of lymphocytes into the central nervous system (CNS). Synonyms: SB-683699; SB 683699; SB683699; T-0047; T 0047; T0047; Firategrast. Grade: >98%. CAS No. 402567-16-2. Molecular formula: C27H27F2NO6. Mole weight: 499.5. | |
| Firazorexton | Firazorexton is a potent orexin type 2 receptor (OX2R) agonist extracted from patent WO2019027058A1, example 395. CAS No. 2274802-95-6. Molecular formula: C22H25F3N2O4S. Mole weight: 470.51. | |
| Firefly luciferase-IN-1 | Firefly luciferase-IN-1 is a highly potent and reversible inhibitor of firefly luciferase with an IC50 value of 0.25 nM. Synonyms: (E)-6-(4-methylbenzylidene)-5-oxo-5,6,7,8-tetrahydronaphthalene-2-carboxylic acid. CAS No. 2765796-41-4. Molecular formula: C19H16O3. Mole weight: 292.33. | |
| Firocoxib | Firocoxib is a selective COX-2 inhibitor that can be used to control postoperative pain and inflammation associated with soft tissue and orthopedic surgery in dogs. Synonyms: ML 1785713; ML-1785713; ML1785713; Equioxx; Previcox. CAS No. 189954-96-9. Molecular formula: C17H20O5S. Mole weight: 336.4. | |
| Firtecan pegol | Firtecan pegol, also known as EZN-2208,Pegylated SN-38, or PEG-SN38, is a water-soluble polyethyleneglycol-SN38 conjugate. In vitro, the IC50 of EZN-2208 ranged from 3-24 nM, which was 30- to 45-fold lower than CPT-11 or 2.5- to 3.5-fold higher than SN38. In both an early-disease Raji model and an advanced-disease Daudi model, treatment with multiple doses of EZN-2208 resulted in 90% and 100% cures of animals, respectively (cure defined as no sign of tumors by gross observations at the termination of study). The activity of EZN-2208 was dramatically superior to that of CPT-11 in all three models. The excellent therapeutic efficacy of EZN-2208 in several B-cell NHL xenograft models merits its evaluation in the clinic for lymphoid malignancies. Synonyms: EZN-2208 (Pegylated SN-38). PEG-SN38, Firtecan pegol. CAS No. 946062-05-1. Molecular formula: C118H122N12O37. Mole weight: 2300.321. | |
| Firzacorvir | Firzacorvir is a cyclic sulfamide compound that regulates HBV core protein and has anti-HBV activity with an EC50 of <1 μM. Synonyms: (3S,5R)-N-(3-chloro-4-fluorophenyl)-2-methyl-5-(5-(1-methyl-1H-imidazol-4-yl)thiazol-2-yl)-1,2,6-thiadiazinane-3-carboxamide 1,1-dioxide. Grade: ≥98% (HPLC). CAS No. 2243747-96-6. Molecular formula: C18H18ClFN6O3S2. Mole weight: 484.96. | |
| Fisonate | An inhibitor of serine proteinases of broad spectrum. Synonyms: Phosphonic acid, P-[1-methyl-1-[[3,3,3-trifluoro-1-oxo-2-(trifluoromethyl)propyl]amino]propyl]-, diethyl ester. Grade: 99 % (NMR). CAS No. 132742-32-6. Molecular formula: C12H20F6NO4P. Mole weight: 387.26. | |
| FIT-039 | FIT-039 is a potent and selective inhibitor of cyclin-dependent kinase 9 (CDK9), which suppresses replication of a broad spectrum of DNA viruses through inhibition of mRNA transcription. Synonyms: FIT-039|1113044-49-7|CID 25186688|N-(5-fluoro-2-piperidin-1-ylphenyl)pyridine-4-carbothioamide|SCHEMBL14803325|EX-A4710|ZINC150288174|NCGC00402254-02|AC-36620|HY-18944|CS-0014657|N-[5-fluoro-2-(1-piperidyl)phenyl]pyridine-4-carbothioamide|N-(5-fluoro-2-(piperidin-1-yl) phenyl)pyridine-4-carbothioamide. Grade: 98.02%. CAS No. 1113044-49-7. Molecular formula: C17H18FN3S. Mole weight: 315.4. | |
| FITC-abaloparatide | A Fluorescein isothiocyanate-attached Abaloparatide. Abaloparatide is a parathyroid hormone-related protein (PTHrP) analog drug used to treat osteoporosis. Grade: 95%. | |
| FITM | FITM is a potent mGlu1 inhibitor (Ki = 2.5 nM) with great selectivity that does not disrupt mGlu5. Synonyms: Benzamide, 4-fluoro-N-methyl-N-[4-[6-[(1-methylethyl)?amino]?-4-pyrimidinyl]?-2-thiazolyl]?-; 4-Fluoro-N-methyl-N-[4-[6-[(1-methylethyl)amino]-4-pyrimidinyl]-2-thiazolyl]benzamide; 4-Fluoro-N-[4-[6-(isopropylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]-N-methylbenzamide. CAS No. 932737-65-0. Molecular formula: C18H18FN5OS. Mole weight: 371.43. | |
| FK-330 | FK-330 is a novel inducible nitric oxide synthase inhibitor for preventing ischemia and reperfusion injury in rat liver transplantation. Uses: A novel inducible nitric oxide synthase inhibitor. Synonyms: FK-330; FK 330; FK330; 2-Pyridinepropanamide, alpha-(((2E)-3-(4-chlorophenyl)-1-oxo-2-propen-1-yl)amino)-N-(2-oxo-2-(4-((6-(trifluoromethyl)-4-pyrimidinyl)oxy)-1-piperidinyl)ethyl)-, (alphaS)-. Grade: ≥98%. CAS No. 442198-67-6. Molecular formula: C29H28ClF3N6O4. Mole weight: 617.02. | |
| FK330 dihydrate | FK330 dihydrate is a novel inducible nitric oxide synthase inhibitor. It could prevent ischemia and reperfusion injury in rat liver transplantation. Uses: Fk330 dihydrate could prevent ischemia and reperfusion injury in rat liver transplantation. Synonyms: FR260330 dihydrate; FR 260330 dihydrate; FR-260330 dihydrate; FK-330 dihydrate; FK 330 dihydrate. Grade: 98%. CAS No. 682813-92-9. Molecular formula: C29H32ClF3N6O6. Mole weight: 653.05. | |
| FK 3311 | FK 3311 is a selective COX-2 inhibitor. Synonyms: FK-3311; FK3311. CAS No. 116686-15-8. Molecular formula: C15H13F2NO4S. Mole weight: 341.33. | |
| FK-506 3'-Methyl Ether | It is a fermentation process impurity of Tacrolimus, which is a macrolide drug that is widely used as a potent immunosuppressant. Uses: It is a fermentation process impurity. it is formed during tacrolimus ((f370000) fermentation using strain of streptomyces tsukubaensis. Synonyms: 3-[2-(3,4-Dimethoxycyclohexyl)-1-methylethenyl]-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone. Grade: 95%. CAS No. 124554-16-1. Molecular formula: C45H71NO12. Mole weight: 818.04. | |
| FK866 | FK866 is a non-competitive inhibitor of nicotinamide phosphoribosyltransferase (Nampt) with potential antineoplastic and antiangiogenic activities. FK866 binds to Nampt to suppress the biosynthesis of nicotinamide adenine dinucleotide (NAD+), leading to tumor cell apoptosis. Uses: Potential anticancer agent. Synonyms: Daporinad; (E)-N-[4-(1-benzoylpiperidin-4-yl)butyl]-3-pyridin-3-ylprop-2-enamide; APO 866; FK 866; APO866; FK866; APO-866; FK-866. CAS No. 658084-64-1. Molecular formula: C24H29N3O2. Mole weight: 391.515. | |
| FK 866 hydrochloride | FK 866 hydrochloride is a non-competitive and potent inhibitor of NAMPT (nicotinamide phosphoribosyltransferase, visfatin, PBEF1) (Ki = 0.3 nM) and inhibits NAD biosynthesis. It induces delayed cell death by apoptosis in HepG2 human liver carcinoma cells (IC50 ~1 nM)and induces apoptosis in four different neuroblastoma cell lines. FK 866 exhibits antineoplastic and antiangiogenic activities. Synonyms: FK-866 Hydrochloride; FK 866 Hydrochloride; FK866 Hydrochloride; 2-(E)-N-[4-(1-Benzoyl-4-piperidinyl)butyl]-3-(3-pyridinyl)-2-propenamide hydrochloride. Grade: ≥98% by HPLC. CAS No. 2727965-45-7. Molecular formula: C24H29N3O2.HCl. Mole weight: 427.97. | |
| FK 888 | FK 888 is a potent and selective tachykinin NK1 receptor antagonist (Ki = 0.69 nM) with 320-fold selectivity for human over rat NK1 receptors. It inhibits substance P-induced contraction of isolated guinea pig trachea (IC50 = 32 nM) and inhibits substance P-induced airway constriction in vivo following i.v. and oral administration. Synonyms: FK-888; FK 888; FK888. (4R)-4-Hydroxy-1-[(1-methyl-1H-indol-3-yl)carbonyl]-L-prolyl-N-methyl-3-(2-naphthalenyl)-N-(phenylmethyl)-L-alaninamide; (2S,4R)-N-[(2S)-1-[benzyl(methyl)amino]-3-naphthalen-2-yl-1-oxopropan-2-yl]-4-hydroxy-1-(1-methylindole-3-carbonyl)pyrrolidine-2-carboxamide. Grade: ≥98% by HPLC. CAS No. 138449-07-7. Molecular formula: C36H36N4O4. Mole weight: 588.69. | |
| FK 960 | FK 960 is a somatostatin receptor agonist and a 5-HT agonist activating both serotonin and somatostatin production as a cognitive enhancer. The phase II clinical trial for the treatment of Alzheimer's disease is discontinued. Synonyms: FK-960; FK 960; FK960; 60MMJ100ZX; N-(4-acetyl-1-piperazinyl)-4-fluorobenzamide. Grade: 99%. CAS No. 133920-70-4. Molecular formula: C13H16FN3O2. Mole weight: 265.28. | |
| FK962 | FK962 is an enhancer of somatostatin release, with cognitive enhancement and anti-dementia activity. Synonyms: FK-962; N-[1-Acetylpiperidin-4-Yl]-4-Fluorobenzamide. Grade: 98%. CAS No. 283167-06-6. Molecular formula: C14H17FN2O2. Mole weight: 264.29. | |
| FKGK 11 | FKGK 11 is a potent and selective inhibitor of iPLA2 with an XI(50) value of 0.0073. In contrast, it dispalys little or no inhibition against GIVA cPLA2 (XI(50) >0.91). Synonyms: 1,1,1,2,2-pentafluoro-7-phenyl-3-heptanone. Grade: ≥98%. CAS No. 1071000-98-0. Molecular formula: C13H13F5O. Mole weight: 280.2. | |
| FKGK 18 | FKGK 18 is a potent and selective inhibitor of group VIA (GVIA) calcium-independent phospholipase A2 (iPLA2). It displays 195 and >455 times more potent for GVIA iPLA(2) than for GIVA cPLA(2) and GV sPLA(2). Synonyms: 1,1,1-trifluoro-6-(2-naphthalenyl)-2-hexanone. Grade: ≥95%. CAS No. 1071001-09-6. Molecular formula: C16H15F3O. Mole weight: 280.3. | |
| FL118 | FL118 is a potent and orally active survivin inhibitor. It has significant cytotoxic activity against tumor cell lines and inhibits protein synthesis in these cells. Synonyms: Mdo-cpt; 10,11-Methylenedioxycamptothecin; 10,11-Methylenedioxy-20S-camptothecin; (4S)-4-Ethyl-4-hydroxy-8,9-methylenedioxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione. CAS No. 135415-73-5. Molecular formula: C21H16N2O6. Mole weight: 392.36. | |
| FL-411 | FL-411 is a potent and selective BRD4 inhibitor with IC50 of 0.43 μM for BRD4(1). Synonyms: BRD4-IN-1; 2-(4-Hydroxy-3,5-Dimethylphenyl)-7-Methyl-5,6,7,8-Tetrahydropyrido[4',3':4,5]thieno[2,3-D]pyrimidin-4(3h)-One. CAS No. 2118944-88-8. Molecular formula: C18H19N3O2S. Mole weight: 341.43. | |
| FLAG peptide (TFA salt) | FLAG peptide, an eight amino acids peptide with an enterokinase-cleavage site, is a frequently applied hydrophilic and immunogenic fusion tag which was specifically designed to facilitate rapid purification by immunoaffinity chromatography. Synonyms: H-Asp-Tyr-Lys-Asp-Asp-Asp-Asp-Lys-OH.TFA; L-alpha-aspartyl-L-tyrosyl-L-lysyl-L-alpha-aspartyl-L-alpha-aspartyl-L-alpha-aspartyl-L-alpha-aspartyl-L-lysine trifluoroacetate salt; FLAG peptide TFA salt; DYKDDDDK Peptide TFA salt. Molecular formula: C41H60N10O20 (free base). Mole weight: 1012.97 (free base). | |
| Flanvotumab | Flanvotumab is a human monoclonal antibody directed against tyrosinase-related protein (TYRP1). Flanvotumab binds to gp75, resulting in the induction of cytotoxic T cell immune and antibody-mediated immune responses against melanoma cells expressing gp75. Synonyms: IMC-20D7S. Grade: 95%. CAS No. 1188277-05-5. Molecular formula: C6470H9986N1714O2018S46. Mole weight: 145.5 kDa. | |
| Flavine Adenine Dinucleotide-13C5 Ammonium Salt | Labelled Flavine Adenine Dinucleotide. The prosthetic group of certain flavoproteins including D-amino acid oxidase, glucose oxidase, glycine oxidase, fumaric hydrogenase, histaminase, and xanthine oxidase. Riboflavin kinase tumor necrosis factor receptor 1 NADPH oxidase. Synonyms: Riboflavin 5'-(Trihydrogen Diphosphate) P'5'-Ester with Adenosine-13C5 Ammonium Salt; Adenine-flavine Dinucleotide-13C5 Disodium; Adenine-riboflavin-13C5 Dinucleotide Ammonium Salt; Adenine-riboflavine-13C5 Dinucleotide Ammonium Salt; FAD-13C5 Ammonium Salt; Fademin-13C5 Ammonium Salt; Flavinat-13C5 Ammonium Salt; Flavine Adenosine Diphosphate-13C5 Ammonium Salt; Flavitan-13C5 Ammonium Salt; NSC 112207; Riboflavin-adenine Dinucleotide-13C5 Dinucleotide Ammonium Salt. Grade: 95%; 99% atom 13C. Molecular formula: C22[13C]5H33N9O15P2 xNH3. Mole weight: 790.51. | |
| Flavopiridol Hydrochloride | Flavopiridol hydrochloride competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4 and CDK6 with IC50 of ~ 40 nM. It is 7.5-fold more selective for CDK1/2/4/6 than CDK7. Flavopiridol is initially found to inhibit EGFR and PKA. Synonyms: NSC 649890 HCl; NSC649890 HCl; NSC-649890 HCl. Grade: >98%. CAS No. 131740-09-5. Molecular formula: C21H20ClNO5.HCl. Mole weight: 438.3. | |
| Flavoxate | Flavoxate is an anticholinergic with antimuscarinic effects. Flavoxate blocks L-type calcium channels and acts an antagonist of muscarinic acetylcholine receptors. Uses: Parasympatholytics. Synonyms: Flavoxato; Flavoxatum; 2-(1-piperidyl)ethyl 3-methyl-4-oxo-2-phenylchromene-8-carboxylate; 2-piperidinoethyl 3-methylflavone-8-carboxylate. Grade: > 95%. CAS No. 15301-69-6. Molecular formula: C24H25NO. Mole weight: 391.47. | |
| Flavoxate-d5 | An isotope labelled Flavoxate. Flavoxate is an anticholinergic with antimuscarinic effects. Synonyms: 2-(1-piperidyl)ethyl 3-methyl-4-oxo-2-phenylchromene-8-carboxylate-d5. Grade: > 95%. Molecular formula: C24H20NO4D5. Mole weight: 396.50. | |
| Flavoxate HCL | Flavoxate is an anticholinergic with antimuscarinic effects. Its muscle relaxant properties may be due to a direct action on the smooth muscle rather than by antagonizing muscarinic receptors. Uses: Parasympatholytics. Synonyms: NSC-114649; NSC 114649; NSC114649. Grade: >98%. CAS No. 3717-88-2. Molecular formula: C24H25NO4.HCl. Mole weight: 427.92. | |
| Flazasulfuron | Flazasulfuron is an herbicide used for pre-emergence and early post-emergence weed control. Flazasulfuron inhibits the enzyme acetolactate synthase (ALS). CAS No. 104040-78-0. Molecular formula: C13H12F3N5O5S. Mole weight: 407.33. | |
| Flecainide | Flecainide is a class 1C antiarrhythmic drug especially used for the management of supraventricular arrhythmia; works by blocking the Nav1.5 sodium channel in the heart, causing prolongation of the cardiac action potential. Uses: Voltage-gated sodium channel blockers. Synonyms: (±)-Flecainide; N-(2-Piperidinylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide; Flecaine; Benzamide, N-(2-piperidinylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)-; NSC-719273. Grade: ≥95%. CAS No. 54143-55-4. Molecular formula: C17H20F6N2O3. Mole weight: 414.35. | |
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