BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Dapagliflozin Impurity 32 | Dapagliflozin Impurity 32 is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: Dapagliflozin MonoAcetyl Impurity; Dapagliflozin Methyl Acetate; ((2R,3S,4R,5R,6S)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)methyl acetate. Grades: >90%. CAS No. 1632287-34-3. Molecular formula: C23H27ClO7. Mole weight: 450.91. |  |
| Dapagliflozin Impurity 33 | Dapagliflozin Impurity 33 is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Molecular formula: C30H35ClO11. Mole weight: 607.04. | |
| Dapagliflozin Impurity 35 | Dapagliflozin Impurity 35 is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Molecular formula: C31H35ClO12. Mole weight: 635.05. | |
| Dapagliflozin Impurity 36 | Dapagliflozin Impurity 36 is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: 6-Acetoxymethyl-3,4,5-triacetoxy-6-methoxy Dapagliflozin Dimer. Molecular formula: C57H64Cl2O20. Mole weight: 1140.01. | |
| Dapagliflozin Impurity 37 | Dapagliflozin Impurity 37 is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: 6-Acetoxymethyl-3,4,5-triacetoxy-6-oxo Dapagliflozin. Molecular formula: C41H47ClO19. Mole weight: 879.25. | |
| Dapagliflozin Impurity 38 | Dapagliflozin Impurity 38 is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). CAS No. 2452300-92-2. Molecular formula: C27H33ClO12. Mole weight: 585. | |
| Dapagliflozin Impurity 39 | Dapagliflozin Impurity 39 is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: 4-(5-Bromo-2-chlorobenzyl)phenol. Grades: >95%. CAS No. 864070-18-8. Molecular formula: C13H10BrClO. Mole weight: 297.57. | |
| Dapagliflozin Impurity 3 (S)-(+)-1,2-Propanediol Monohydrate | Dapagliflozin Impurity 3 (S)-(+)-1,2-Propanediol Monohydrate is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: 4-Dechloro-4-bromo Dapagliflozin (S)-(+)-1,2-Propanediol Monohydrate; Dapagliflozin 4-bromo Impurity (S)-(+)-1,2-Propanediol Monohydrate. Molecular formula: C21H25BrO6.C3H8O2.H2O. Mole weight: 547.43. | |
| Dapagliflozin Impurity 4 | Dapagliflozin Impurity 4 is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: 1-rac-Dapagliflozin 1,4-Anhydro Form. Grades: >95%. Molecular formula: C21H25ClO6. Mole weight: 408.87. | |
| Dapagliflozin Impurity 5 | Dapagliflozin Impurity 5 is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: 1-C-[4-Chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol; Dapagliflozin Open Ring Impurity. Grades: >90%. CAS No. 2100872-88-4. Molecular formula: C21H27ClO7. Mole weight: 426.89. | |
| Dapagliflozin Impurity 55 | Dapagliflozin Impurity 55 is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: 2-chloro-5-bromobenzoic acid chloride. Grades: >95%. CAS No. 21900-52-7. Molecular formula: C7H3BrCl2O. Mole weight: 253.91. | |
| Dapagliflozin Impurity 6 | Dapagliflozin Impurity 6 is an impurity of Dapagliflozin. Dapagliflozin (BMS 512148) is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: 5-bromo-2-chloro-4'-ethoxybenzophenone; Dapagliflozin Bromomethanone. Grades: > 95 %. CAS No. 461432-22-4. Molecular formula: C15H12BrClO2. Mole weight: 339.61. | |
| Dapagliflozin Impurity 7 | Dapagliflozin Impurity 7 is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: Dapagliflozin Dimer Impurity; 4,4'-Dichloro-3-(3-ethoxybenzyl)-3'-(4-ethoxybenzyl)-1,1'-biphenyl. Grades: >90%. CAS No. 2176485-21-3. Molecular formula: C30H28Cl2O2. Mole weight: 491.45. | |
| Dapagliflozin Impurity 8 | Dapagliflozin Impurity 8 is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: 1-rac-Dapagliflozin. Molecular formula: C21H25ClO6. Mole weight: 408.87. | |
| Dapagliflozin Impurity S2A | Dapagliflozin Impurity S2A is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: (2S,3R,4S,5R,6R)-5-Hydroxy Dapagliflozin. Molecular formula: C21H25ClO7. Mole weight: 424.87. | |
| Dapagliflozin Methoxy Tetraacetate | Dapagliflozin Methoxy Tetraacetate is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: (2S,3R,4S,5R,6R)-6-(acetoxymethyl)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triyl triacetate. CAS No. 714269-58-6. Molecular formula: C30H35ClO11. Mole weight: 607.05. | |
| Dapagliflozin Open Sugar Impurity | Dapagliflozin Open Sugar Impurity is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: Dapagliflozin open sugar impurity; 1-C-[4-Chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol; (2S,3R,4R,5R)-1-(4-Chloro-3-(4-ethoxybenzyl)phenyl)hexane-1,2,3,4,5,6-hexaol; Dapagliflozin ring opening impurity; (1R,2S,3R,4R)-1-(4-Chloro-3-(4-ethoxybenzyl)phenyl)hexane-1,2,3,4,5,6-hexaol. Molecular formula: C21H27ClO7. Mole weight: 426.89. | |
| Dapagliflozin propanediol | Dapagliflozin propanediol is the salt of Dapagliflozin, which is a selective, orally active renal sodium-glucose cotransporter type 2 (SGLT2) inhibitor used for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: Dapagliflozin propanediol anhydrous; D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-, (1S)-, compd. with (2S)-1,2-propanediol (1:1); Dapagliflozin S-propylene glycol; (2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol, (2S)-propane-1,2-diol (1:1). Grades: ≥95%. CAS No. 1971128-01-4. Molecular formula: C21H25ClO6.C3H8O2. Mole weight: 484.97. | |
| Dapagliflozin-(R)-Furanose | Dapagliflozin-(R)-Furanose is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: (1R)-1,4-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol. Grades: >95%. CAS No. 1469910-83-5. Molecular formula: C21H25ClO6. Mole weight: 408.87. | |
| Daphnin | Daphnin is isolated from the whole herb of Daphne odora (Thunb.), with antibacterial activity. Synonyms: 7-(beta-D-glucopyranosyloxy)-8-hydroxycoumarin; Daphnoside; 8-hydroxy-2-oxo-2H-chromen-7-yl beta-D-glucopyranoside. CAS No. 486-55-5. Molecular formula: C15H16O9. Mole weight: 340.28. | |
| Dapiprazole Hydrochloride | Dapiprazole Hydrochloride is a salt form of Dapiprazole, an alpha-1-adrenergic antagonist. Dapiprazole inhibits alpha-adrenergic receptors in the smooth muscle of blood vessels (arteries, arterioles and veins), gastrointestinal tract, and radial smooth muscle of the iris, resulting in vasodilatation. Synonyms: Dapiprazole HCl; Rev-Eyes; 3-[2-[4-(2-methylphenyl)piperazin-1-yl]ethyl]-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyridine hydrochloride. CAS No. 72822-13-0. Molecular formula: C19H28ClN5. Mole weight: 361.918. | |
| Dapivirine | Dapivirine, also known as TMC 120, TMC 120 R147681, is a NNRTI for HIV reverse transcriptase with IC50 of 24 nM, inhibiting a broad panel of HIV-1 isolates from different classes, inclucing a wide range of NNRTI-resistant isolates. Synonyms: TMC120; TMC 120; TMC-120; R 147681; R-147681; R147681; Dapivirine. Grades: 99.90%. CAS No. 244767-67-7. Molecular formula: C20H19N5. Mole weight: 329.407. | |
| Dapoxetine (Free Base) | Grades: > 95%. CAS No. 119356-77-3. Molecular formula: C21H23NO. Mole weight: 305.42. | |
| Dapoxetine N-Oxide | Dapoxetine N-Oxide is an impurity of Dapoxetine. Dapoxetine HCl is a novel short-acting selective serotonin reuptake inhibitor. Synonyms: (α S) -N, N-Dimethyl-N-oxido-α -[2- (1-naphthalenyloxy) ethyl]benzenemethanamine. Grades: 90%. CAS No. 1346603-24-4. Molecular formula: C21H23NO2. Mole weight: 321.41. | |
| Dapsone Hydroxylamine | Dapsone Hydroxylamine is a metabolite of Dapsone. Synonyms: N-Hydroxy-4,4'-sulfonyldi(aniline); N-Hydroxy-4,4'-sulfonyldi-aniline; 4-[(4-Aminophenyl)sulfonyl]-N-hydroxy-benzenamine. Grades: > 95%. CAS No. 32695-27-5. Molecular formula: C12H12N2O3S. Mole weight: 264.3. | |
| Dapsone Impurity 1 | 4-Chlorophenyl Phenyl Sulfone is an impurity of Dapson, an antibacterial used in the treatment of dermatitis herpetiformis. Synonyms: 4-Chlorophenyl Phenyl Sulfone; 4-Chlorodiphenyl Sulfone; 4-Chlorophenyl Phenyl Sulfone; NSC 404335; R 242; Sulfenon; Sulphenone; p-Chlorodiphenyl Sulfone; p-Chlorophenyl Phenyl Sulfone; p-Chlorophenyl Phenyl Sulfone; 1-Chloro-4-(phenylsulfonyl)benzene. Grades: > 95%. CAS No. 80-00-2. Molecular formula: C12H9ClO2S. Mole weight: 252.72. | |
| Dapsone Impurity 2 | 4-Amino-4'-chlorodiphenyl sulfone is a substituted 4-aminodiphenylsulfone as Escherichia coli dihydropteroate synthase inhibitor. Synonyms: 4-Amino-4'-chlorodiphenyl Sulfone; 4-[(4-Chlorophenyl)sulfonyl]benzenamine; p-[(p-Chlorophenyl)sulfonyl]aniline; 4-(4-Chlorobenzenesulfonyl)phenylamine; 4-Amino-4'-chlorodiphenyl Sulfone; 4-Aminophenyl 4-chlorophenyl Sulfone; NSC 23812; NSC 51990; p-(p-Ch. Grades: > 95%. CAS No. 7146-68-1. Molecular formula: C12H10ClNO2S. Mole weight: 267.73. | |
| Dapsone Impurity 3 | 4-Amino-4'-hydroxydiphenylsulfone is a diaryl sulfone with antileprotic activity. 4-Amino-4'-hydroxydiphenylsulfone is an antibacterial agent. Synonyms: 4-Amino-4'-hydroxydiphenylsulfone; 4-[(4-Aminophenyl)sulfonyl]phenol; p-Sulfanilylphenol. Grades: > 95%. CAS No. 25963-47-7. Molecular formula: C12H11NO3S. Mole weight: 249.29. | |
| Dapsone Impurity 4 | 4-Phenylsulfonylaniline is used in the preparation of novel Flufenamic acid analogues as inhibitors of androgen receptor mediated transcription. Synonyms: 4-Phenylsulfonylaniline; 4-(Phenylsulfonyl)benzenamine; p-(Phenylsulfonyl)aniline; 4-(Benzenesulfonyl)aniline; 4-(Benzenesulphonyl)phenylamine; 4-(Phenylsulfonyl)benzenamine; 4-Aminodiphenyl Sulfone; 4-Aminophenyl Phenyl Sulfone; 4-Phenylsulfonylaniline. Grades: > 95%. CAS No. 7019-1-4. Molecular formula: C12H11NO2S. Mole weight: 233.29. | |
| Dapsone Impurity 5 | 2,4'-Diaminophenyl Sulfone is used in biological studies as dapsone leprosy inhibitor. 2,4'-Diaminophenyl Sulfone is also an impurity of dapsone which is an antibacterial used in the treatment of dermatitis herpetiformis. Synonyms: 2,4'-Diaminophenyl Sulfone; 2,4'-Sulfonyldi-aniline; 2,4'-Diaminodiphenyl Sulfone; 2,4'-Diaminophenyl Sulfone; 4,2'-Bis(aminophenyl) Sulfone; 2-[(4-Aminophenyl)sulfonyl]-benzenamine. Grades: > 95%. CAS No. 27147-69-9. Molecular formula: C12H12N2O2S. Mole weight: 248.3. | |
| Daptomycin Impurity-1 | Daptomycin Impurity-1 is an impurity of Daptomycin, which is a lipopeptide antibiotic used to treat systemic infections and life-threatening infections caused by gram-positive organisms. Synonyms: Daptomycin Impurity B1/2; N-decanoyl-L-tryptophyl-D-asparginyl-L-aspartyl-L-threonylglycyl-L-ornathyl-L-aspartic acid. Molecular formula: C44H66N10O15. Mole weight: 975.07. | |
| Daptomycin Impurity-3 | Daptomycin Impurity-3 is an impurity of Daptomycin, which is a lipopeptide antibiotic used to treat systemic infections and life-threatening infections caused by gram-positive organisms. Synonyms: N-decanoyl-Trp-D-Asn-Asp-Thr-Gly-Orn-Asp-D-Ser-Asp-Gly-D-Ser-3Me-Glu-Kyn-OH (ε1-lactone); 8-D-Serinedaptomycin; Daptomycin, 8-D-serine-. CAS No. 921590-20-7. Molecular formula: C72H101N17O27. Mole weight: 1636.69. | |
| Daptomycin Impurity-6 | Daptomycin Impurity-6 is an impurity of Daptomycin, which is a lipopeptide antibiotic used to treat systemic infections and life-threatening infections caused by gram-positive organisms. Synonyms: N-decanoyl-Trp-D-Asn-Asp-Thr-Gly-Orn-Asp-Ser-Asp-Gly-D-Ser-3Me-Glu-Kyn-OH (ε1-lactone); Daptomycin RS-6; 8-L-Serinedaptomycin. Molecular formula: C72H101N17O27. Mole weight: 1636.69. | |
| Daptomycin Impurity-7 | Daptomycin Impurity-7 is an impurity of Daptomycin, which is a lipopeptide antibiotic used to treat systemic infections and life-threatening infections caused by gram-positive organisms. Synonyms: N-decanoyl-Trp-D-Asn-Asp-Thr-Gly-Orn-Asp-Abu-Asp-Gly-D-Ser-3Me-Glu-Kyn-OH (ε1-lactone); Daptomycin RS-7; 8-L-2-Aminobutyric acid-daptomycin. Molecular formula: C73H103N17O26. Mole weight: 1634.72. | |
| Daptomycin Impurity-8 | Daptomycin Impurity-8 is an impurity of Daptomycin, which is a lipopeptide antibiotic used to treat systemic infections and life-threatening infections caused by gram-positive organisms. Synonyms: N-decanoyl-Trp-D-Asn-Asp-Thr-Gly-Orn-Asp-D-Ala-Asp-Gly-D-Ser-3Me-Glu-Phe-OH (ε1-lactone); Daptomycin RS-8; Daptomycin impurity-35; N-decanoyl-L-tryptophyl-D-asparginyl-L-aspartyl-L-threonylglycyl-L-ornithyl-L-aspartyl-D-alanyl-L-aspartylglycyl-D-serylthreo-3-methyl-L-glutamyl-L-Phenylalanine (ε1-lactone). Molecular formula: C71H100N16O25. Mole weight: 1577.67. | |
| Daptomycin Impurity-B1/II | Daptomycin Impurity-B1/II is an impurity of Daptomycin, which is a lipopeptide antibiotic used to treat systemic infections and life-threatening infections caused by gram-positive organisms. Synonyms: N-decanoyl-L-tryptophyl-D-asparginyl-L-aspartyl-L-threonylglycyl-L-ornithine-L-aspartyl-D-alanine. Molecular formula: C47H71N11O16. Mole weight: 1046.15. | |
| Daptomycin Impurity-B2 | Daptomycin Impurity-B2 is an impurity of Daptomycin, which is a lipopeptide antibiotic used to treat systemic infections and life-threatening infections caused by gram-positive organisms. Synonyms: N-decanoyl-L-tryptophyl-D-asparginyl-L-aspartyl-L-threonylglycyl-L-ornithine; L-Ornithine, N-(1-oxodecyl)-L-tryptophyl-D-asparaginyl-L-α-aspartyl-L-threonylglycyl-. CAS No. 866822-35-7. Molecular formula: C40H61N9O12. Mole weight: 859.98. | |
| Daptomycin Impurity RS-7b | Daptomycin Impurity RS-7b is an impurity of Daptomycin, which is a lipopeptide antibiotic used to treat systemic infections and life-threatening infections caused by gram-positive organisms. Synonyms: N-decanoyl-L-tryprophyl-D-asparginyl-L-aspartyl-L-threonyl (L-aspartyl-D-alanyl-L-aspartylglycyl-D-serylthreo-3-methyl-L-glutamyl-3-anthraniloyl-L-alanine ε1-lactone)glycyl-L-ornathine; N-dec-Trp-D-Asn-Asp-Thr-Gly-Orn-OH-Asp-D-Ala-Gly-D-Ser-3Me-Glu-Kyn-OH (ε1-lactone). Molecular formula: C72H103N17O27. Mole weight: 1638.71. | |
| Daptomycin Isodecy acyl isomer | Daptomycin Isodecy acyl isomer is an impurity of Daptomycin, which is a lipopeptide antibiotic used to treat systemic infections and life-threatening infections caused by gram-positive organisms. Synonyms: Isodecylacyl-Trp-D-Asn-Asp-Thr-Gly-Orn-Asp-D-Ala-Asp-Gly-D-Ser-3Me-Glu-Kyn-OH (ε1-lactone); Daptomycin impurity-32; 1-[N-(8-Methyl-1-oxononyl)-L-tryptophan]daptomycin; Daptomycin, 1-[N-(8-methyl-1-oxononyl)-L-tryptophan]-; N-(8-Methylnonanoyl)-L-tryptophyl-L-asparaginyl-N-[(3S,6S,9R,15S,18R,21S,24S,30S,31R)-3-[2-(2-aminophenyl)-2-oxoethyl]-24-(3-aminopropyl)-15,21-bis(carboxymethyl)-6-[(2R)-1-carboxy-2-propanyl]-9-(hydroxymethyl)-18,31-dimethyl-2,5,8,11,14,17,20,23,26,29-decaoxo-1-oxa-4,7,10,13,16,19,22,25,28-nonaazacyclohentriacontan-30-yl]-L-α-asparagine. CAS No. 1233389-15-5. Molecular formula: C72H101N17O26. Mole weight: 1620.69. | |
| Daptomycin (RS-1) | Daptomycin (RS-1) is an impurity of Daptomycin, which is a lipopeptide antibiotic used to treat systemic infections and life-threatening infections caused by gram-positive organisms. Synonyms: Daptomycin Impurity-1. Molecular formula: C72H103N17O27. Mole weight: 1638.71. | |
| Daptomycin RS-4 | Daptomycin RS-4 is an impurity of Daptomycin, which is a lipopeptide antibiotic used to treat systemic infections and life-threatening infections caused by gram-positive organisms. Synonyms: 3-OH-Dodecanoyl-Trp-D-Asn-Asp-Thr-Gly-Orn-Asp-D-Ala-Asp-Gly-D-Ser-3Me-Glu-Kyn-OH (ε1-lactone); Daptomycin Impurity-4; Benzenebutanoic acid, N-(3-hydroxy-1-oxododecyl)-L-tryptophyl-D-asparaginyl-L-α-aspartyl-L-threonylglycyl-L-ornithyl-L-α-aspartyl-D-alanyl-L-α-aspartylglycyl-D-seryl-(3R)-3-methyl-L-α-glutamyl-α,2-diamino-γ-oxo-, (13?4)-lactone, (αS)-. Molecular formula: C74H105N17O27. Mole weight: 1664.75. | |
| Daptomycin RS-5 | Daptomycin RS-5 is an impurity of Daptomycin, which is a lipopeptide antibiotic used to treat systemic infections and life-threatening infections caused by gram-positive organisms. Synonyms: N-decanoyl-L-tryptophyl-D-asparginyl-L-aspartyl-L-threonylglycyl-L-ornithyl-L-aspartyl-glycyl-L-asprtyl-glycyl-D-serylthreo-3-methyl-L-glutamyl-3-anthraniloyl-L-alanine (ε1-lactone); Daptomycin RS-5; Daptomycin Impurity-5. Molecular formula: C71H99N17O26. Mole weight: 1606.67. | |
| Darapladib | Darapladib (SB-480848) is a reversible lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor with IC50 of 0.25 nM. Synonyms: SB-480848; SB 480848; SB480848; Darapladib. Grades: >98%. CAS No. 356057-34-6. Molecular formula: C36H38F4N4O2S. Mole weight: 666.77. | |
| D-Arg(8)-AVP | D-Arg(8)-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: D-Arg(8)-Vasopressin; D-Arg-AVP; Vasopressin, 8-D-arginine-; H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-D-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-D-arginyl-glycinamide (1->6)-disulfide; 8-D-Argininevasopressin; D-Arginine-vasopressin; (D-Arg8)vasopressin. CAS No. 5591-81-1. Molecular formula: C46H65N15O12S2. Mole weight: 1084.24. | |
| Darunavir N-β-D-Glucuronide | Darunavir N-β-D-Glucuronide is a metabolite of Darunavir, an inhibitor of human immunodeficiency virus protease. Synonyms: 1-Deoxy-1-[[4-[[[ (2R, 3S) -3-[[[[ (3R, 3aS, 6aR) -hexahydrofuro[2, 3-b]furan-3-yl]oxy]carbonyl]amino]-2-hydroxy-4-phenylbutyl] (2-methylpropyl) amino]sulfonyl]phenyl]amino]-β -D-glucopyranuronic Acid. Grades: > 95%. CAS No. 1159613-25-8. Molecular formula: C33H45N3O13S. Mole weight: 723.79. | |
| Darunavir-O-Glucuronide | Darunavir-O-Glucuronide is a metabolite of Darunavir, an inhibitor of human immunodeficiency virus protease. Synonyms: Darunavir O-β-D-Glucuronide. Grades: > 95%. CAS No. 1159613-27-0. Molecular formula: C33H45N3O13S. Mole weight: 723.79. | |
| Darusentan | Darusentan is a selective endothelin-1 receptor A inhibitor. Darusentan is identified as the treatment of congestive heart failure, hypertension and cancers. It blocks endothelin ETA receptor thus results in an increase of sodium and potassium excretion in aging rats. Uses: Endothelin receptor antagonists. Synonyms: LU-135252; LU135252; LU 135252; HMR-4005; HMR 4005; HMR4005; (2S)-2-(4,6-dimethoxypyrimidin-2-yl)oxy-3-methoxy-3,3-diphenylpropanoic acid. Grades: 95%. CAS No. 171714-84-4. Molecular formula: C22H22N2O6. Mole weight: 410.426. | |
| dasabuvir | Dasabuvir is an antiviral drug for the treatment of hepatitis C. It inhibits hepatitis C virus (HCV) non-nucleoside NS5B palm polymerase to suppress RNA replicase. Dasabuvir is commonly used in combination with ombitasvir/paritaprevir/ritonavir to effect on HCV type 1. Uses: The treatment of hepatitis c. Synonyms: ABT333; ABT-333; ABT 333, Dasabuvir. Trade names: Viekira Pak (with ombitasvir/paritaprevir/ritonavir tablets), Exviera; N-(6-(3-(tert-butyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-methoxyphenyl)naphthalen-2-yl)methanesulfonamide. Grades: 98.40%. CAS No. 1132935-63-7. Molecular formula: C26H27N3O5S. Mole weight: 493.578. | |
| Dasatinib Carboxylic Acid | Dasatinib Carboxylic Acid is an oxidative metabolite of Dasatinib (M6 metabolite), used in the treatment of cancers and immune diseases. Synonyms: 4-[6-[[5-[[(2-Chloro-6-methylphenyl)amino]carbonyl]-2-thiazolyl]amino]-2-methyl-4-pyrimidinyl]-1-piperazineacetic Acid. Grades: > 95%. CAS No. 910297-53-9. Molecular formula: C22H24ClN7O3S. Mole weight: 501.99. | |
| Dasatinib Dimeric Impurity | Dasatinib Dimeric Impurity is an impurity of Dasatinib (M24 metabolite), used in the treatment of cancers and immune diseases. Synonyms: 2,2'-((6,6'-(Piperazine-1,4-diyl)bis(2-methylpyrimidine-6,4-diyl))bis(azanediyl))bis(N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide). Grades: ≥95%. CAS No. 910297-61-9. Molecular formula: C36H34Cl2N12O2S2. Mole weight: 801.77. | |
| Dasatinib Impurity 2 | Cas No. 302964-24-5. | |
| Dasatinib Impurity 5 | Dasatinib Impurity 5 isan impurity of Dasatinib, a targeted therapy for chronic myeloid leukemia and certain types of acute lymphoblastic leukemia. Synonyms: 2-(4-(6-((5-((2-Chloro-6-methylphenyl)carbamoyl)thiazol-2-yl)amino)-2-methylpyrimidin-4-yl)piperazin-1-yl)ethyl acetate. Grades: > 95%. CAS No. 1245157-85-0. Molecular formula: C24H28ClN7O3S. Mole weight: 530.04. | |
| D-Asn(5)-AVP | D-Asn(5)-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: D-Asn-Vasopressin; D-Asn-AVP; H-Cys-Tyr-Phe-Gln-D-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-D-asparagyl-L-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-disulfide; Vasopressin, 5-D-asparagine-8-L-arginine-; 5-D-asparagine-Argipressin. CAS No. 2075715-46-5. Molecular formula: C46H65N15O12S2. Mole weight: 1084.24. | |
| D-Asn 5-Oxytocin | D-Asn 5-Oxytocin is an impurity of Oxytocin, which is a mammalian neurohypophysial hormone used as a vasodilator agent. Synonyms: L-cystyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-D-asparginyl-L-cystyl-L-leucyl-L-prolyl-L-glycinamide (disulfide bridge between cysteines); H-Cys-Tyr-Ile-Gln-D-Asn-Cys-Pro-Leu-Gly-NH2 (Disulfide bridge: Cys1-Cys6); Oxytocin, 5-D-asparagine-; [5-D-Asparagine]oxytocin; [D-Asn5]-Oxytocin; L-cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-D-asparagyl-L-cysteinyl-L-prolyl-L-leucyl-glycinamide (1->6)-disulfide. Grades: ≥95%. CAS No. 5754-53-0. Molecular formula: C43H66N12O12S2. Mole weight: 1007.19. | |
| Dasotraline hydrochloride | Dasotraline hydrochloride, also called as SEP-225289 hydrochloride, is a metabolite of Sertraline and a novel inhibitor of dopamine and norepinephrine reuptake that blocks dopamine, norepinephrine, andserotonin transporters (IC50 = 4, 6, and 11 nM, respectively). Synonyms: (1R,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-amine;hydrochloride; SEP-225,289; SEP225,289; SEP225,289; SEP-225289; SEP225289; SEP225289;; Dasotraline; Dasotraline HCl; Dasotraline hydrochloride. CAS No. 675126-08-6. Molecular formula: C16H16Cl3N. Mole weight: 328.66. | |
| Daunorubicin HCl EP Impurity F | Cas No. 771423-67-7. | |
| DBeQ | DBeQ inhibits p97 competitively with respect to ATP, with Ki of 3.2 μM, suggesting that it binds to the active site of the D2 domain. Synonyms: DBeQ; DBEQ; JRF12; JRF-12; JRF 12. Grades: >98%. CAS No. 177355-84-9. Molecular formula: C22H20N4. Mole weight: 340.42. | |
| DBG-1 Cyclised | Cas No. 1702936-92-2. | |
| DBG-3D diacid | DBG-3D diacid is an impurity of Dabigatran, an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with atrial fibrillation. Synonyms: 4-(((5-((2-Carboxyethyl)(pyridin-2-yl)carbamoyl)-1-methyl-1H-benzo[d]imidazol-2-yl)methyl)amino)benzoic acid; Dabigatran Impurity 69. CAS No. 1253792-34-5. Molecular formula: C25H23N5O5. Mole weight: 473.49. | |
| DCC-2618 | DCC-2618 inhibits normal and mutant KIT kinase at the nanomol level. The targets are wt c-KIT, c-KIT mutants, PDGFR alpha, PDGFR beta, KDR and cFMS. DCC-2618 inhibits mutant KIT in GIST patient cell line (GIST T1 pKIT western Ex11 deletion) at a IC 50 of 2 nM. Deciphera's technology has identified DCC-2618 as a molecule which can be developed as second line therapy for imatinib and sunitinib resistant GIST patients with the potential to progress to frontline GIST therapy. DCC-2618 has been designed to effectively inhibit the imatinib and sunitinib-sensitive KIT juxtamembrane domain mutants (JMD) as well as secondary resistant KIT kinase-domain mutants. DCC-2618 additionally targets PDGFR alpha oncogenic mutants. Synonyms: DCC2618; DCC 2618; c-Kit-IN-1; PDGFR inhibitor 1; N-[2,5-Difluoro-4-[[2-(1-methyl-1H-pyrazol-4-yl)-4-pyridinyl]oxy]phenyl]-N'-phenyl-1,1-cyclopropanedicarboxamide. Grades: >98%. CAS No. 1225278-16-9. Molecular formula: C26H21F2N5O3. Mole weight: 489.47. | |
| DCPIB | DCPIB is a potent and selective volume-sensitive anion channel (VSAC) blocker, swell in various cardiovascular tissues (IC50 = 4.1 μM in CPAE cells). It inhibits glucose-stimulated insulin in intact β-cells, and reverses cell swelling-induced action potential duration shortening in atrial myocytes and inhibits astroglial swelling in vitro. Synonyms: 4-[(2-Butyl-6,7-dichloro-2-cyclopentyl-2,3-dihydro-1-oxo-1H-inden-5-yl)oxy]butanoic acid. Grades: ≥98% by HPLC. CAS No. 82749-70-0. Molecular formula: C22H28Cl2O4. Mole weight: 427.37. | |
| DCVC | DCVC is one of cysteine impurities. It has potential anticancer activity against tumor cell growth. DCVC has been found to influence sort of cytokines release stimulated by pathogen. Uses: Dcvc has been found to influence sort of cytokines release stimulated by pathogen. Synonyms: S-(trans-1,2-Dichlorovinyl)-L-cysteine; (E)-S-(1,2-Dichloroethenyl)-L-cysteine; L-Cysteine, S-((1E)-1,2-dichloroethenyl)-; ALANINE, 3-((1,2-DICHLOROVINYL)THIO)-, (E)-L-; AC1O5GGP. Grades: 98%. CAS No. 13419-46-0. Molecular formula: C5H7Cl2NO2S. Mole weight: 216.09. | |
| D-Cys(1)-AVP | D-Cys(1)-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: D-Cys(1)-Vasopressin; Vasopressin, 1-D-cysteine-8-L-arginine-; H-D-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); D-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-disulfide. CAS No. 66513-07-3. Molecular formula: C46H65N15O12S2. Mole weight: 1084.24. | |
| D-Cys(2)-Octreotide | D-Cys(2)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: D-phenylalanyl-D-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7); Octreotide Impurity-6; H-D-Phe-D-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr-ol (Disulfide bridge: Cys2-Cys7); D-Phenylalanyl-D-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-L-cysteinamide cyclic (2?7)-disulfide; L-Cysteinamide, D-phenylalanyl-D-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2?7)-disulfide, [R-(R*,R*)]-; L-Cysteinamide, D-phenylalanyl-D-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2?7)-disulfide. CAS No. 108102-47-2. Molecular formula: C49H66N10O10S2. Mole weight: 1019.25. | |
| D-Cys(4)-Terlipressin Trifluoroacetic Acid Salt | D-Cys(4)-Terlipressin Trifluoroacetic Acid Salt is an impurity of Terlipressin, which is a partial agonist of the vasopressin V1A receptor used as a vasoactive drug in the management of low blood pressure. Synonyms: (2S) -1-[ (4R, 7S, 10S, 13S, 16S, 19S) -19-[[2-[[2-[ (2-aminoacetyl) amino]acetyl]amino]acetyl]amino]-7- (2-amino-2-oxoethyl) -10- (3-amino-3-oxopropyl) -13-benzyl-16-[ (4-hydroxyphenyl) methyl]-6, 9, 12, 15, 18-pentaoxo-1, 2-dithia-5, 8, 11, 14, 17-pentazacycloicosane-4-carbonyl]-N-[ (2S) -6-amino-1-[ (2-amino-2-oxoethyl) amino]-1-oxohexan-2-yl]pyrrolidine-2-carboxamide Trifluoroacetic Acid Salt; H-Gly-Gly-Gly-D-Cys(1)-Tyr-Phe-Gln-Asn-Cys(1)-Pro-Lys-Gly-NH2.TFA; glycyl-glycyl-glycyl-D-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-lysyl-glycinamide (4->9)-disulfide TFA. Grades: >98%. Molecular formula: C52H74N16O15S2.xC2HF3O2. Mole weight: 1227.37 (free base). | |
| D-Cys(6)-AVP | D-Cys(6)-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: D-Cys(6)-Vasopressin; Vasopressin, 6-D-cysteine-8-L-arginine-; H-Cys-Tyr-Phe-Gln-Asn-D-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-D-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-disulfide. CAS No. 163659-75-4. Molecular formula: C46H65N15O12S2. Mole weight: 1084.24. | |
| D-Cys(7)-Octreotide | D-Cys(7)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: D-phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-D-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7); H-D-Phe-Cys-Phe-D-Trp-Lys-Thr-D-Cys-Thr-ol (Disulfide bridge: Cys2-Cys7); D-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2?7)-disulfide. CAS No. 1211530-36-7. Molecular formula: C49H66N10O10S2. Mole weight: 1019.25. | |
| D-(+)-Darunavir | Synonyms: (+)-Darunavir; 1399859-60-9; D-(+)-Darunavir; Darunavir, (+)-; NCL9DHY4E3; UNII-NCL9DHY4E3; (3S,3aR,6aS)-Hexahydrofuro(2,3-b)furan-3-yl ((2R,3S)-4-((4-amino-N-isobutylphenyl)sulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate; [(3aR,4S,6aS)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] N-[(2R,3S)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]carbamate; Carbamic acid, N-((1R,2S)-3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-(phenylmethyl)propyl)-, (3S,3aR,6aS)-hexahydrofuro(2,3-b)furan-3-yl ester; (3S,3aR,6aS)-Hexahydrofuro[2,3-b]furan-3-yl ((2R,3S)-4-((4-amino-N-isobutylphenyl)sulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate. Grades: > 95%. CAS No. 1399859-60-9. Molecular formula: C27H37N3O7S. Mole weight: 547.66. | |
| Deacetylasperulosidic acid | Deacetylasperulosidic acid is a natural compound found in Morinda citrifolia fruit with antioxidant activity. Deacetylasperulosidic acid inhibited the reduction of ear swelling, and also cancelled the suppression of IL-2 production along with the activation of natural killer cells in the same manner as that of Noni-ext. Synonyms: (1S,4aS,5S,7aS)-1-(β-D-Glucopyranosyloxy)-1,4a,5,7a-tetrahydro-5-hydroxy-7-(hydroxymethyl)cyclopenta[c]pyran-4-carboxylic acid. Grades: >98%. CAS No. 14259-55-3. Molecular formula: C16H22O11. Mole weight: 390.34. | |
| Deacetyl Linezolid | Cas No. 168828-90-8. | |
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