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Ustusolate A
Ustusolate A is produced by Aspergillus ustus and exerts weak cytotoxicity against HL-60 and A549 cells with IC50 values of 20.6 and 30.0 microM, respectively. Synonyms: 6-O-(octa-2E,4E,6E-trienoyl)-12-hydroxy-6-epi-albrassitriol; 2,4,6-Octatrienoic acid, (1R,4S,4aS,8aS)-1,4,4a,5,6,7,8,8a-octahydro-4-hydroxy-3,4-bis(hydroxymethyl)-4a,8,8-trimethyl-1-naphthalenyl ester, (2E,4E,6E)-. Grade: ≥98%. CAS No. 1136611-58-9. Molecular formula: C23H34O5. Mole weight: 390.51.
Ustusolate C
Ustusolate C is produced by Aspergillus ustus. Study shows that it has moderate cytotoxicity against A549 and HL-60 cells. Synonyms: 9α-hydroxy-6β-(7-hydroxyocta-2E,4E-dienoyloxy)-5α-drim-7-en-11,12-olide; 2,4-Octadienoic acid, 7-hydroxy-, (5R,5aS,9aS,9bS)-1,3,5,5a,6,7,8,9,9a,9b-decahydro-9b-hydroxy-6,6,9a-trimethyl-1-oxonaphtho[1,2-c]furan-5-yl ester, (2E,4E)-. Grade: 97.0%. CAS No. 1188398-15-3. Molecular formula: C23H32O6. Mole weight: 404.50.
Ustusolate E
Ustusolate E is a metabolite of marine-derived fungus Aspergillus ustus 094102. Ustusolate E exhibits cytotoxic activity against A549 and HL-60 cell lines. Synonyms: 9α-hydroxy-6β-(6-oxohex-2E,4E-dienoyloxy)-5α-drim-7-en-11,12-olide; 2,4-Hexadienoic acid, 6-oxo-, (5R,5aS,9aS,9S)-1,3,5,5a,6,7,8,9,9a,9b-decahydro-9b-hydroxy-6,6,9a-trimethyl-1-oxonaphtho[1,2-c]furan-5-yl ester, (2E,4E)-. Grade: 93.0%. CAS No. 1175543-06-2. Molecular formula: C21H26O6. Mole weight: 374.43.
Val-Cit-PAB-MMAE
Val-Cit-PAB-MMAE, a tubulin polymerase inhibitor, is a drug-linker conjugate for ADC. It contains an ADC linker (peptide Val-Cit-PAB) and a potent tubulin inhibitor MMAE. Synonyms: L-Valyl-N-{4-[(5S,8S,11S,12R)-11-[(2S)-2-butanyl]-12-(2-{(2S)-2-[(1R,2R)-3-{[(1S,2R)-1-hydroxy-1-phenyl-2-propanyl]amino}-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl}-2-oxoethyl)-5,8-diisopropyl-4,10-dimethyl-3,6,9-trioxo-2,13-dioxa-4,7,10-triazatetradec-1-yl]phenyl}-N5-carbamoyl-L-ornithinamide. Grade: ≥98%. CAS No. 644981-35-1. Molecular formula: C58H94N10O12. Mole weight: 1123.43.
Vancomycin-[d10] monoacetate salt
Vancomycin-[d10] monoacetate salt is the labelled acetate form of Vancomycin. Vancomycin monoacetate salt exhibits potent activity against Gram-positive bacteria, and high effects against MRSA in vitro and in vivo. It interferes with cell wall synthesis by binding to D-alanine-D-alanine residues. Synonyms: [D10]-Vancomycin monoacetate salt; D10-Vancomycin monoacetate salt; Vancomycin-d10 monoacetate salt. Grade: >98%. Molecular formula: C68H69D10Cl2N9O26. Mole weight: 1519.38.
Vancomycin-[d10] trifluoroacetate salt
Labelled Vancomycin trifluoroacetate salt. Vancomycin is a tricyclic glycopeptide antibiotic. It inhibits cell wall synthesis in Gram-positive bacteria. Synonyms: [D10]-Vancomycin (trifluoroacetate salt); Vancomycin-d10 trifluoroacetate salt; Vancomycin-d10 TFA salt. Molecular formula: C66H65D10Cl2N9O24.C2F3O2H. Mole weight: 1573.34.
Vancomycin-[d12] trifluoroacetate salt
Vancomycin-[d12] trifluoroacetate salt is the labelled analogue of Vancomycin trifluoroacetate salt. Vancomycin is a glycopeptide antibiotic medication used to treat a number of bacterial infections. Synonyms: Vancomycin-[d12] TFA salt; Vancomycin trifluoroacetate salt-d12; d12-Vancomycin trifluoroacetate salt. Molecular formula: C66H63D12Cl2N9O24.C2F3O2H. Mole weight: 1575.35.
(-)-Variabilin
(-)-Variabilin is a phenolic compound found in the herbs of Angelica sinensis. (-)-Variabilin exhibits activity of antimicrobial and is an important chemotaxonomic marker for the family Irciniidae. Uses: Antimicrobial. Synonyms: (-)-Homopisatin; 6a-Hydroxy-3,9-dimethoxypterocarpan; (6aS,11aS)-3,9-Dimethoxy-6H-benzofuro[3,2-c][1]benzopyran-6a(11aH)-ol. Grade: >97%. CAS No. 370102-93-5. Molecular formula: C17H16O5. Mole weight: 300.3.
Veratric Acid-[d6]
Veratric Acid-[d6] is the deuterated form of Veratric Acid which is a natural phenol found in the fruits of Phyllanthus emblica L. Synonyms: 3,4-Dimethoxybenzoic Acid-d6; Dimethylprotocatechuic Acid-d6; NSC 7721-d6. Grade: ≥90%. CAS No. 1162658-12-9. Molecular formula: C9H4D6O4. Mole weight: 188.21.
(+)-Viroallosecurinine
Viroallosecurinine is a natural alkaloid compound found in several plants. Synonyms: Virosecurinine; Allosecurinin; Phyllochrysine; Allosecurinine; (7R,9R)-Securinan-11-one; Alkaloid PN-A. Grade: >95%. CAS No. 1857-30-3. Molecular formula: C13H15NO2. Mole weight: 217.26.
Vitamin K1
Vitamin K1 is a fat-soluble vitamin that occurs widely in green plants, algae, photosynthetic bacteria. Vitamin K1 serves as a precursor to vitamin K2 and is essential for the synthesis of proteins required for blood-clotting, bone metabolism, and cell growth. It is commonly used in dietary supplement for the treatment of bleeding disorders. Vitamin supplement in health care products. Uses: Ingredient of health care products. Synonyms: Phytonadione; Phytomenadione; Phylloquinone; 3-Phytylmenadione; E-Phytonadione; 2-Methyl-3-[(2E,7R,11R)-3,7,11,15-tetramethyl-2-hexadecenyl]-1,4-naphthalenedione; Konakion; Mephyton; Phytylmenadione; Phytylmenaquinone; Synthex P; Veda K1; Veta K1; trans-Phylloquinone; α-Phylloquinone; 2',3'-trans-Vitamin K1; [R-[R*,R*-(E)]]-2-Methyl-3-(3,7,11,15-tetramethyl-2-hexadecenyl)-1,4-naphthalenedione; Antihemorrhagic Vitamin; Haemokion; Kativ N; Kaywan; Kenadion; Kephton; Kinadion; Konakion; Mono-Kay; Monodion; NSC 270681; Orakay; Pediatrico; Phylloquinone K1; Reconval. Grade: 97.0-103.0%. CAS No. 84-80-0. Molecular formula: C31H46O2. Mole weight: 450.71.
Vonoprazan-[d3]
Vonoprazan-[d3] is a labelled Vonoprazan, a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+ ATPase with IC50 of 19 nM (pH 6.5), controls gastric acid secretion. Synonyms: Vonoprazan-d3. Molecular formula: C17H13D3FN3O2S. Mole weight: 348.4.
Vosoritide
Vosoritide is a medicine used to treat achondroplasia. Vosoritide works by binding to a receptor (target) called natriuretic peptide receptor type B (NPR-B), which reduces the activity of fibroblast growth factor receptor 3 (FGFR3). Uses: Vosoritide, a synthetic analog of the human growth hormone receptor antagonist bmp-7, has emerged as a promising candidate in drug development, particularly in the area of ??rare genetic diseases characterized by impaired skeletal growth and development. achondroplasia is the most common form of disproportionate dwarfism and is characterized by abnormal skeletal growth and development, especially. Synonyms: Voxzogo; BMN-111. Grade: ≥95%. CAS No. 1480724-61-5. Molecular formula: C176H290N56O51S3. Mole weight: 4103.
Wilforlide A
Wilforlide A is extracted from the herb of Tripterygium wilfordii Hook.f. It has obvious anti-inflammatory effect at high-dose. Uses: Wilforlide a has obvious anti-inflammatory effect at high-dose, but has no significant immune suppressive activity. Synonyms: Regelide; Abruslactone A; (3β,22α)-3-Hydroxy-22,29-epoxyolean-12-en-29-one; Wilforlide; Olean-12-en-29-oic acid, 3,22-dihydroxy-, γ-lactone, (3β,20α,22α)-; 3-epiabruslactone A. Grade: ≥98%. CAS No. 84104-71-2. Molecular formula: C30H46O3. Mole weight: 454.68.
XMC-[d3]
XMC-[d3] is a deuterium labelled 3,5-Xylyl methylcarbamate, an acetylcholinesterase inhibitor used as an insecticide. Synonyms: XMC-d3; 3,5-Xylyl methylcarbamate-d3; Cosban-d3; Maqbarl-d3; Macbal-d3. Molecular formula: C10H10D3NO2. Mole weight: 182.23.
Xylometazoline-[d4] Hydrochloride
Xylometazoline-[d4] Hydrochloride is the labelled hydrochloride of Xylometazoline. Xylometazoline is an α-adrenoceptor agonist commonly used as a nasal decongestant, which exhibits highest potency at α2B-adrenoceptor subtype with EC50 of 99 μM. Synonyms: 2-{[4-tert-butyl-2,5-dimethyl(D2)phenyl](D2)methyl}-4,5-dihydro-1H-imidazole hydrochloride. Molecular formula: C16H21D4ClN2. Mole weight: 284.86.
YAP-TEAD Inhibitor 1
YAP-TEAD Inhibitor 1 is a potent inhibitor of YAP-TEAD interaction with IC50 value of 25 nM. Synonyms: YAP-TEAD-IN-1; YAP-TEAD (Peptide 17). Grade: 98%. CAS No. 1659305-78-8. Molecular formula: C93H144ClN23O21S2. Mole weight: 2019.86.
(Z)-Akuammidine
(Z)-Akuammidine, which is isolated from the roots of Gelsemium elegans, was found to be potent μ-opioid agonists. Synonyms: (19Z)-Rhazine. Grade: >98%. CAS No. 113973-31-2. Molecular formula: C21H24N2O3. Mole weight: 352.4.
Zeaxanthin
Zeaxanthin is a carotenoid xanthophyll that plays a role in the xanthophyll cycle. Zeaxanthin is a pigment that gives paprika (made from bell peppers), corn, saffron, wolfberries, and many other plants and microbes their characteristic color. It is used for eye health. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: Anchovyxanthin; Xanthophyll 3; Zeaxanthol; all-trans-Zeaxanthin; Beta,beta-carotene-3,3'-diol; all-E-Zeaxanthin; all-trans-3R,3'R-Zeaxanthin; all-trans-Anchovyxanthin; Luteinofta; Optisharp; (3R,3'R)-Dihydroxy-β-carotene; (3R,3'R)-Zeaxanthin; (3R,3'R)-β,β-Carotene-3,3'-diol; (3R,3'R)-all-trans-β-Carotene-3,3'-diol. Grade: 5% by HPLC. CAS No. 144-68-3. Molecular formula: C40H56O2. Mole weight: 568.89.