BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Zanamivir Azide Triacetate Methyl Ester | An intermediate used in the preparation of Zanamivir derivatives. Synonyms: (1S,2R)-1-((2R,3R,4S)-3-acetamido-4-azido-6-(methoxycarbonyl)-3,4-dihydro-2H-pyran-2-yl)propane-1,2,3-triyl triacetate; 5-(acetylamino)-2,6-anhydro-4-azido-3,4,5-trideoxy-, methyl ester, 7,8,9-triacetate; Methyl 5-acetamido-7,8,9-O-triacetyl-2,6-anhydro-4-azido-3,4,5-trideoxy-D-glycero-D-galacto-non-2-enonate. Grades: 95%. CAS No. 130525-58-5. Molecular formula: C18H24N4O10. Mole weight: 456.41. |  |
| Zanamivir (hydrate) | Zanamivir is a neuraminidase inhibitor used in the treatment and prophylaxis of influenza caused by influenza A virus and influenza B virus. Synonyms: Relenza; GG 167; 2,3-Didehydro-2,4-dideoxy-4-guanidine-N-acetyl-acetyl-D-neuraminic acid; 4-Guanidino-2,4-dideoxy-2,3-didehydro-N-acetylneuraminic acid; 5-Acetamino-2,6-anhydro-4-guanidino-3,4,5-trideoxy-D-galcto-non-enoic acid. Grades: >98%. CAS No. 139110-80-8. Molecular formula: C12H22N4O8. Mole weight: 350.33. | |
| Zanubrutinib | Zanubrutinib is a potent and irreversible BTK inhibitor. It is used as a medication for the treatment of Chronic Lymphocytic Leukemia. Uses: Antineoplastic agents. Synonyms: BGB-3111; BGB 3111; BGB3111. CAS No. 1691249-45-2. Molecular formula: C27H29N5O3. Mole weight: 471.55. | |
| (Z)-ethyl 3-ethoxy-2-(2,4,5-trifluoro-3-methoxybenzoyl)acrylate | An impurity of Moxifloxacin, a fourth-generation antibacterial drug. Synonyms: 2-(2,4,5-Trifluoro-3-methoxybenzoyl)-3-ethoxyacrylic Acid Ethyl Ester; α-(Ethoxymethylene)-2,4,5-trifluoro-3-methoxy-β-oxobenzenepropanoic Acid Ethyl Ester; Moxifloxacin Impurity 36. CAS No. 866954-86-1. Molecular formula: C15H15F3O5. Mole weight: 332.27. | |
| Z-Guggulsterone | Z-Guggulsterone is a broad spectrum steroid receptor ligand that acts as a mineralocorticoid, progesterone and glucocorticoid receptor antagonist (Ki = 37, 224 and 252 nM, respectively) and weak androgen receptor agonist (Ki = 315 nM). Z-Guggulsterone is also a selective antagonist of farnesoid X receptor (FXR) exhibiting antilipidemic, antiseptic, antirheumatic and anti-inflammatory activity in vivo. Synonyms: (Z)-Pregna-4,17(20)-diene-3,16-dione. Grades: ≥98% by HPLC. CAS No. 39025-23-5. Molecular formula: C21H28O2. Mole weight: 312.45. | |
| Zibotentan | Zibotentan is an orally administered, potent and specific ETA-receptor (endothelin A receptor) antagonist (IC50 = 21 nM). Synonyms: ZD4054; ZD-4054; ZD 4054; N-(3-methoxy-5-methylpyrazin-2-yl)-2-[4-(1,3,4-oxadiazol-2-yl)phenyl]pyridine-3-sulfonamide. Grades: >98%. CAS No. 186497-07-4. Molecular formula: C19H16N6O4S. Mole weight: 424.44. | |
| Zidebactam | Zidebactam is a β-lactamase inhibitor which possesses intrinsic antibacterial activity. Zidebactam is undergoing clinical development for the treatment of carbapenem-resistant Gram-negative infections. Uses: Bacterial infections. Synonyms: WCK-5107; WCK 5107; WCK5107; Zidebactam; (1R,2S,5R)-7-oxo-2-(2-((R)-piperidine-3-carbonyl)hydrazine-1-carbonyl)-1,6-diazabicyclo[3.2.1]octan-6-yl hydrogen sulfate. Grades: 98%. CAS No. 1436861-97-0. Molecular formula: C13H21N5O7S. Mole weight: 391.40. | |
| (Z)-JIB-04 | (Z)-JIB-04 is a Z-isomer of JIB-04, which is a small-molecule histone demethylase inhibitor with antitumor activity. JIB-04 selectively inhibits tumor growth via targeting various tumorigenic signaling pathways. Synonyms: 5-Chloro-2-(2-(phenyl(pyridin-2-yl)methylene)hydrazinyl)pyridine; JIB-04 Z-isomer. CAS No. 199596-24-2. Molecular formula: C17H13ClN4. Mole weight: 308.769. | |
| ZLN005 | Selective transcriptional regulator of peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α). ZLN005 selectively stimulated the expression of PGC-1α and downstream genes in skeletal muscle cells, and led to changes in glucose uptake, and fatty acid oxidation in L6 myotubes in a AMPK dependent manner. Since ZLN 005 did not increase the expression of the PGC-1α gene in rat primary hepatocytes, it is hypothesized that expression of PGC-1α was regulated in a cell type-specific manner. ZLN005 exerts promising therapeutic effects for treating type 2 diabetes, as PGC-1α is a powerful transcriptional coregulator of GLUT4 and mitochondrial genes, a crucial player in the field of glucose uptake in skeletal muscle. Synonyms: ZLN005; ZLN-005; ZLN 005. Grades: >98%. CAS No. 49671-76-3. Molecular formula: C17H18N2. Mole weight: 250.34. | |
| (Z)-methyl 2-ethoxy-1-((2'-(N'-hydroxycarbamimidoyl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-carboxylate | (Z)-methyl 2-ethoxy-1-((2'-(N'-hydroxycarbamimidoyl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-carboxylate is an impurity of Azilsartan, an angiotensin II receptor blocker (ARB) used to treat high blood pressure. Synonyms: Methyl 2-ethoxy-1-[[2 ²-(hydroxyamidino)biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylate; 2-Ethoxy-1-[[2'-[(hydroxyamino)iminomethyl][1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic Acid Methyl Ester. CAS No. 147403-65-4. Molecular formula: C25H24N4O4. Mole weight: 444.48. | |
| (Z)-methyl 3-((2'-(N'-hydroxycarbamimidoyl)-[1,1'-biphenyl]-4-yl)methyl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-4-carboxylate | (Z)-methyl 3-((2'-(N'-hydroxycarbamimidoyl)-[1,1'-biphenyl]-4-yl)methyl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-4-carboxylate is an impurity of Azilsartan, an angiotensin II receptor blocker (ARB) used to treat high blood pressure. Grades: 98%. CAS No. 1499167-72-4. Molecular formula: C23H20N4O4. Mole weight: 416.43. | |
| (Z)-Methyl 3- ( ( (4- (N-methyl-2- (piperazin-1-yl)acetamido)phenyl)amino) (phenyl)methylene)-2-oxoindoline-6-carboxylate | An impurity of Nintedanib, a receptor tyrosine kinase (RTK) inhibitor that binds to vascular endothelial growth factor receptor, fibroblast growth factor receptor and platelet derived growth factor receptor. Nintedanib is used as a medication for the treatment of idiopathic pulmonary fibrosis. Synonyms: Nintedanib metabolite M3; Nintedanib impurity I; 1H-Indole-6-carboxylic acid, 2, 3-dihydro-3- [ [ [4- [methyl [2- (1-piperazinyl) acetyl] amino] phenyl] amino] phenylmethylene] -2-oxo-, methyl ester, (3Z)-. Grades: ≥95%. CAS No. 334951-61-0. Molecular formula: C30H31N5O4. Mole weight: 525.60. | |
| Zofenopril Calcium Salt | Zofenopril Calcium is an antioxidant and acts as an angiotensin-converting enzyme (ACE) inhibitor. lt is also an inhibitor of PEPT2, the predominant peptide transporter in kidney and choroid plexus. lt is a pro-drug designed to undergo metabolic hydrolysis yielding the active free sulfhydryl compound zofenoprilat. lt promotes the regeneration of peripheral nerve injuries in rat models. lt increases SR calcium cycling and stimulates active calcium uptake into the SR. It was developed by the Bristol Myers Squibb Company. Uses: Zofenopril calcium promotes the regeneration of peripheral nerve injuries in rat models. lt increases sr calcium cycling and stimulates active calcium uptake into the sr. Synonyms: SQ26991; SQ 26991; SQ-26991; (4S)-N-[3-(benzoylsulfanyl)-2(s)-methylpropionyl]-4-(phenylsulfanyl)-l-proline calcium salt;[1(S),4(S)]-1-(3-Mercapto-2-methyl-1-oxopropyl)-4-phenyl-thio-L-proline-S-benzoyl Ester Calcium Salt;[(4S)-(2S)-3-(benzoylthio)-2-methylpro-pionyl-4-(phenylthio)-L-prolinelcalcium;Calcium;(2S,4S)-1-[(2S)-3-benzoylsulfanyl-2-methylpropanoyl]-4-phenylsulfanylpyrrolidine-2-carboxylate. Grades: 95%. CAS No. 81938-43-4. Molecular formula: C44H44CaN2O8S4. Mole weight: 897.17. | |
| Zopolrestat | Zopolrestat is an inhibitor of Aldose Reductase(AR). It has been shown to play roles in inflammation and cancer. It is used for the treatment of diabetic nephropathy and cardiac disease. It was developed by Pfizer and was terminated in clinic phase 2 trials. Uses: Zopolrestat is used for the treatment of diabetic nephropathy and cardiac disease. Synonyms: 3-[(5-Trifluoromethyl-2-benzothiazolyl)methyl]-3,4-dihydro-4-oxophthalazine-1-acetic acid;CP-73850;3,4-Dihydro-4-oxo-3-[[5-(trifluoromethyl)-2-benzothiazolyl]methyl]-1-phthalazineacetic acid;Alond;Xedia;2-[4-Oxo-3-[[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl]phthalazin-1-yl]acetic acid;CP 73850; CP73850; CP-73850; Zopolrestat; Zopolrestatum. Grades: 95%. CAS No. 110703-94-1. Molecular formula: C19H12F3N3O3S. Mole weight: 419.38. | |
| Zosuquidar trihydrochloride | Zosuquidar (LY335979) is a potent modulator of P-glycoprotein-mediated multi-drug resistance with a Ki value of 60 nM. Synonyms: LY 335979; LY-335979; D06387; RS-33295-198; Zosuquidar HCl. CAS No. 167465-36-3. Molecular formula: C32H34Cl3F2N3O2. Mole weight: 636.99. | |
| (Z)-tert-Butyl 2-(2-(2-(Tritylamino)thiazol-4-yl)-2-((trityloxy)imino)acetamido)acetate | (Z)-tert-Butyl 2-(2-(2-(Tritylamino)thiazol-4-yl)-2-((trityloxy)imino)acetamido)acetate is one of Cefdinir intermediates. Cefdinir is a semi-synthetic, broad-spectrum antibiotic, used for soft tissue infections and respiratory tract infections. Synonyms: 2-Methyl-2-propanyl N-{(2Z)-2-[2-(tritylamino)-1,3-thiazol-4-yl]-2-[(trityloxy)imino]acetyl}glycinate; Glycine, N-[(2Z)-1-oxo-2-[(triphenylmethoxy)imino]-2-[2-[(triphenylmethyl)amino]-4-thiazolyl]ethyl]-, 1,1-dimethylethyl ester. Molecular formula: C49H44N4O4S. Mole weight: 784.96. | |
| (Z)-tetradec-9-enyl acetate | Synonyms: (9Z)-9-Tetradecenyl acetate; (Z)-9-Tetradecen-1-ol acetate; (z)-9-tetradecenyl; (Z)-9-tetradecyl acetate; 9-Tetradecen-1-ol, acetate, (Z)-. Grades: 95%. CAS No. 16725-53-4. Molecular formula: C16H30O2. Mole weight: 254.41. | |
| Zuclopenthixol acetate | Zuclopenthixol is a typical antipsychotic drug that belongs to thioxanthene class. Zuclopenthixol is the cis-isomer of clopenthixol. Zuclopenthixol has not been approved for use in the United States. It is a dopamine D1/D2 receptor antagonist used for the treatment of Schizophrenia. Uses: Schizophrenia. Synonyms: (Z)-4-(3-(2-Chloro-9H-thioxanthen-9-ylidene)propyl)piperazine-1-ethyl acetate; Clopixol-Acuphase. Grades: 98%. CAS No. 85721-05-7. Molecular formula: C24H27ClN2O2S. Mole weight: 443.01. | |
| Zuclopenthixol Decanoate | Zuclopenthixol decanoate is a typical antipsychotic drug belonging to the thioxanthene class. lt has high affinity for both dopamine D1 and D2 receptors, for α1-adrenoceptors and 5-HT2 receptors but has no affinity for cholinergic muscarine receptors. It is used in the maintenance treatment of chronic schizophrenic patients. lt is not approved for use in the United States. It was introduced in 1962 by Lundbeck. Uses: Zuclopenthixol decanoate is used in the maintenance treatment of chronic schizophrenic patients. Synonyms: Clopixol Depot; Decanoic acid, 2-(4-(3-(2-chloro-9H-thioxanthen-9-ylidene)propyl)-1-piperazinyl)ethyl ester, (Z)-. Grades: 95%. CAS No. 64053-00-5. Molecular formula: C32H43ClN2O2S. Mole weight: 555.22. | |
| Zuclopenthixol dihydrochloride | Zuclopenthixol dihydrochloride is an antagonist at D1 and D2 dopamine receptors. Zuclopenthixol also has high affinity for alpha1-adrenergic and 5-HT2 receptors, but it has weaker histamine H1 receptor blocking activity, and even lower affinity for muscarinic cholinergic and alpha2-adrenergic receptors. lt is the cis-isomer of clopenthixol. It is an antipsychotic drug belonging the thioxanthene class. Synonyms: Zuclopenthixol hydrochloride; Clopenthixol cis(Z)-form dihydrochloride. CAS No. 58045-23-1. Molecular formula: C22H27Cl3N2OS. Mole weight: 473.89. | |
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