BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Tetrahydrorhombifoline | Tetrahydrorhombifoline is an indispensable natural compound employed in the research of neurological afflictions such as Alzheimer's disease, Parkinson's disease and epilepsy. Synonyms: tetrahydrorombifoline. CAS No. 3382-84-1. Molecular formula: C15H24N2O. Mole weight: 248.36. |  |
| TG100-115 | TG100-115 is a potent and selective PI3K γ and -δ inhibitor (IC50 values of 83 and 235 nM, respectively) with no effect on PI3Kα or -β (IC50 values > 1 μM). As a gauge of general specificity, TG100-115 was also assayed against a 133 protein kinase panel, none of which was inhibited at IC50 values < 1 μM. Synonyms: TG100115; TG-100115; TG 100115; TG-100-115; TG100-115 ; TG 100-115. 6,7-Bis(3-hydroxyphenyl)pteridine-2,4-diamine; 3,3'-(2,4-diaminopteridine-6,7-diyl)diphenol. CAS No. 677297-51-7. Molecular formula: C18H14N6O2. Mole weight: 346.35. | |
| TGX-221 | TGX-221 is a potent, selective, and cell membrane permeable inhibitor of the PI3K p110β catalytic subunit. Recent studies showed that TGX-221 has antiproliferative activity against PTEN-deficient tumor cell lines including prostate cancers. Synonyms: TGX221; TGX 221; 7-methyl-2-morpholino-9-(1-(phenylamino)ethyl)-4H-pyrido[1,2-a]pyrimidin-4-one. Grades: 98%. CAS No. 663619-89-4. Molecular formula: C21H24N4O2. Mole weight: 364.449. | |
| Theophylline Impurity 4 | Theophyline impurity. Synonyms: 9-(1,3-Dioxolan-2-ylmethyl)-3,9-dihydro-1,3-dimethyl-1H-purine-2,6-dione. Grades: > 95%. CAS No. 1174289-18-9. Molecular formula: C11H14N4O4. Mole weight: 266.25. | |
| Thiamet G | Thiamet G is a potent and selective O-GlcNAcase (OGA) inhibitor with Ki of 21 nM, while exhibiting 37000-fold selectivity over human lysosomal-hexosaminidase. Inhibition of OGA by Thiamet G reduced tau pathology in the brain and total tau in the CSF of rTg4510 mice. Synonyms: Thiamet-G; (3aR,5R,6S,7R,7aR)-2-(Ethylamino)-3a,6,7,7a-tetrahydro-5-(hydroxymethyl)-5H-pyrano[3,2-d]thiazole-6,7-diol. Grades: >98%. CAS No. 1009816-48-1. Molecular formula: C9H16N2O4S. Mole weight: 248.3. | |
| Thiamine Impurity E | An impurity of Thiamine which is an important vitamin in carbohydrate (sugar and starch) metabolism, maintenance of normal growth, and transmission of nerve impulses. Synonyms: Thiothiamine; Thioxothiamine. Grades: > 95%. CAS No. 299-35-4. Molecular formula: C12H16N4OS2. Mole weight: 296.42. | |
| Thio-aripiprazole | Thio-aripiprazole is an atypical antipsychotic. Synonyms: 7-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinoline-2-thione. Grades: 98%. CAS No. 573691-04-0. Molecular formula: C23H27Cl2N3OS. Mole weight: 464.45. | |
| Thio Linezolid | Thio Linezolid is an impurity of Linezolid, an oxazolidinone antimicrobial which inhibits bacterial mRNA translation. Synonyms: Linezolid Related Compound B; Deacetyl Linezolid Thioacetamide; N-[[(5S)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-ethanethioamide. Grades: > 95%. CAS No. 216868-57-4. Molecular formula: C16H20FN3O3S. Mole weight: 353.41. | |
| Thionicotinamide Adenine Dinucleotide | Thionicotinamide Adenine Dinucleotide is utilized as a cofactor. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: Thionicotinamide-DPN. CAS No. 4090-29-3. Molecular formula: C21H27N7O13P2S. Mole weight: 679.491. | |
| Thiorphan | Thiorphan is a potent and specific enkephalinase inhibitor with antinociceptive activity. Uses: Protease inhibitors. Synonyms: N-[2-(Mercaptomethyl)-1-oxo-3-phenylpropyl]glycine; 2-Mercaptomethyl-3-phenylpropionylaminoacetic Acid; D,L-3-Mercapto-2-benzylpropanoylglycine; (+/-)-Thiorphan. Grades: > 95%. CAS No. 76721-89-6. Molecular formula: C12H15NO3S. Mole weight: 253.32. | |
| Thiotepa | Thiotepa is an alkylating agent used to treat cancer, which features tetrahedral phosphorus and is structurally akin to phosphate. Thiotepa has been previously used in the palliation of a wide variety of neoplastic diseases. Uses: Antineoplastic agents, alkylating; myeloablative agonists. Synonyms: AI3 24916; AI324916; AI3-24916; NSC-6396; NSC 6396; NSC6396; thiophosphamide; thiophosphoramide; triethylene thiophosphoramide. Girostan; STEPA; TESPA; Thiofozil; Thioplex; Tifosyl. Ledertepa; Onco Tiotepa; Oncotiotepa; Tespamin; Tespamine; Thiotef; Tio-TEF; TSPA WR 45312. Grades: >98%. CAS No. 52-24-4. Molecular formula: C6H12N3PS. Mole weight: 189.22. | |
| Thioxacillin Potassium Salt | Thioxacillin Potassium Salt is a derivative of Oxacillin, which is used as an antibiotic related to Penicillin. Synonyms: Potassium (2R,5R,6R)-3,3-dimethyl-6-{[(5-methyl-3-phenyl-1,2-oxazol-4-yl)carbonyl]amino}-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carbothioate; 4-Thia-1-azabicyclo[3.2.0]heptane-2-carbothioic acid, 3,3-dimethyl-6-[[(5-methyl-3-phenyl-4-isoxazolyl)carbonyl]amino]-7-oxo-, potassium salt, (2R,5R,6R)- (1:1); (2R,5R,6R)-3,3-Dimethyl-6-{[(5-methyl-3-phenyl-1,2-oxazol-4-yl)carbonyl]amino}-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carbothioate potassium salt. Grades: 95%. Molecular formula: C19H18KN3O4S2. Mole weight: 455.59. | |
| Thozalinone | Thozalinone is a psychostimulant used as an antidepressant. Thozalinone is described as a ''dopaminergic stimulant'' that may act by inducing the release of dopamine and norepinephrine. Synonyms: Stimsen; CL-39808; Tozalinone; Thozalinon; 2-(Dimethylamino)-5-phenyl-2-oxazolin-4-one; CL 39808; NSC 170962; 2-(Dimethylamino)-5-phenyl-1,3-oxazol-4(5H)-one; 2-(Dimethylamino)-5-phenyl-4(5H)-oxazolone. Grades: ≥95%. CAS No. 655-05-0. Molecular formula: C11H12N2O2. Mole weight: 204.22. | |
| threo-Hydroxy Bupropion HCl | Synonyms: SCHEMBL6429264; Threo-dihydrobupropion hydrochloride; (R,R)-Dihydro Bupropion Hydrochloride; AKOS040758080; 357637-18-4. Grades: > 95%. CAS No. 357637-18-4. Molecular formula: C13H21Cl2NO. Mole weight: 278.22. | |
| Thymosin β4 | Thymosin β4 is a potent peptide regulator of actin polymerization naturally present in human platelets at a concentration of 200 - 500 μM. Thymosin β4 is involved in angiogenesis and tumor metastasis. Synonyms: Fx Peptide; Thymosin beta4; Thymosin beta 4; Thymosin beta(4); Thymosin β4; Tβ4; Tb4; Thymosin beta-4; Thymosin β-4; Thymosin β 4; TB-500. Grades: 95% by HPLC. CAS No. 77591-33-4. Molecular formula: C212H350N56O78S. Mole weight: 4963.49. | |
| Thymulin | Thymulin is a nonapeptide produced by thymic epithelial cells. It induces T cell differentiation and various T cell functions in normal or partially thymus-deficient recipients. It also acts as an effector on proinflammatory mediators/cytokines. Synonyms: Serum thymic factor; Thymic factor. CAS No. 63958-90-7. Molecular formula: C33H54N12O15. Mole weight: 858.85. | |
| THZ1 | THZ1 is a selective CDK7 inhibitor that preferentially diminishes transcription in cancer cells. THZ1 has the unprecedented ability to target a remote cysteine residue located outside of the canonical kinase domain, providing an unanticipated means of achieving selectivity for CDK7. Cyclin-dependent kinases (CDKs) are involved in temporal control of the cell cycle and transcription and play central roles in cancer development and metastasis. Synonyms: HY-80013; THZ-1; HY 80013; THZ 1; HY80013; THZ1; N-[3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]phenyl]-4-[[(E)-4-(dimethylamino)but-2-enoyl]amino]benzamide. Grades: >98%. CAS No. 1604810-83-4. Molecular formula: C31H28ClN7O2. Mole weight: 566.062. | |
| Tiadinil | Tiadinil is a plant activator of systemic acquired resistance, boosts the production of herbivore-induced plant volatiles; insecticide agent. Synonyms: 5-(3-Chloro-4-methylanilinocarbonyl)-4-methyl-1,2,3-thiadiazole, N-(3-Chloro-4-methylphenyl)-4-methyl-1,2,3-thiadiazole-5-carboxamide. Grades: >98%. CAS No. 223580-51-6. Molecular formula: C11H10ClN3OS. Mole weight: 267.73. | |
| Tiamulin Related Compound A | An impurity of Tiamulin which is an anti-convulsive medication used in the treatment for panic disorder as are a few other anticonvulsants. Synonyms: Pleuromutilin 22-Tosylate; (3aR,4R,5R,7S,8S,9R,9aS,12R)-8-Hydroxy-4,7,9,12-tetramethyl-3-oxo-7-vinyldecahydro-4,9a-propanocyclopenta[8]annulen-5-yl 2-(tosyloxy)acetate. CAS No. 31716-01-5. Molecular formula: C29H40O7S. Mole weight: 532.7. | |
| Ticarcillin Disodium Salt | Ticarcillin is a semisynthetic antibiotic with a broad spectrum of bactericidal activity against many gram-positive and gram-negative aerobic and anaerobic bacteria. Synonyms: (2S,5R,6R)-6-[[(2R)-Carboxy-3-thienylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid Disodium Salt; 6-[D-(-)-α-Carboxy-3-thienylacetamido]penicillanic Acid Disodium Salt; Direct Fast Turquoise Blue GL; Ticarcillin sodium; disodium [29H,31H-phthalocyaninedisulphonato(4-)-N29,N30,N31,N32]cuprate(2-); AB 2288; AB-2288; AB2288; BRL 2288; BRL2288; BRL-2288. Grades: >98%. CAS No. 29457-07-6. Molecular formula: C15H14N2Na2O6S2. Mole weight: 428.39. | |
| Ticarcilloic Acid | Ticarcilloic Acid is an impurity of Ticarcillin, which is a β-lactam carboxylpenicillin antibiotic used to treat Gram-negative bacteria, particularly Pseudomonas aeruginosa and Proteus vulgaris. Synonyms: [2R-[2α[R*(R*)],4β]]-4-Carboxy-α-[(carboxy-3-thienylacetyl)amino]-5,5-dimethyl-2-thiazolidineacetic Acid; Penicilloic acids of ticarcillin; 2-Thiazolidineacetic acid, 4-carboxy-α-[(carboxy-3-thienylacetyl)amino]-5,5-dimethyl-, [2R-[2α[R*(R*)],4β]]-; 2-Thiazolidineacetic acid, 4-carboxy-α-[[(2R)-2-carboxy-2-(3-thienyl)acetyl]amino]-5,5-dimethyl-, (αR,2R,4S)-. CAS No. 67392-88-5. Molecular formula: C15H18N2O7S2. Mole weight: 402.44. | |
| Timolol Impurity G | An impurity of Ticlopidine which is a potent, highly specific β-adrenergic antagonist, significantly inhibiting both β-l- and β-2-adrenergic agonist activity. Synonyms: 4-(Morpholin-4-yl)-1,2,5-thiadiazol-3(2H)-one-1-oxide. Grades: > 95%. CAS No. 75202-36-7. Molecular formula: C6H9N3O3S. Mole weight: 203.22. | |
| Timolol Maleate | Timolol Maleate is a non-selective, beta-adrenergic receptor antagonist for β1/β2 with Ki of 1.97 nM/2.0 nM. Uses: Adrenergic beta-antagonists. Synonyms: MK-950; MK950; MK950. Grades: >98%. CAS No. 26921-17-5. Molecular formula: C13H24N4O3S.C4H4O4. Mole weight: 432.49. | |
| Tioconazole Related Compound A | One impurity of Tioconazole, which could be used as an antifungal agent and exhibit activities against Candida glabrata mutant strains. Synonyms: 2-Deschlorothien-3-yl Tioconazole Hydrochloride; 1-[2-(2,4-Dichlorophenyl)-2-(3-thienylmethoxy)ethyl]-1H-imidazole Monohydrochloride. CAS No. 61709-33-9. Molecular formula: C16H14Cl2N2OS. HCl. Mole weight: 389.73. | |
| Tiopronin Sulfinic Acid | | |
| Tiotropium bromide hydrate | Tiotropium Bromide hydrate is a monohydrate of tiotropium bromide (Spiriva; Tiova; BA 679BR; tiopropium) that is an anticholinergic and bronchodilator and a muscarinic receptor antagonist. Synonyms: BA 679BR. Grades: >98%. CAS No. 139404-48-1. Molecular formula: C19H22NO4S2.Br.xH2O. Mole weight: 490.43. | |
| Tipiracil HCl | Tipiralacil, also known as TPI, is a thymidine phosphorylase inhibitor (TPI). Tipiracil is one of the active components in TAS-102, which is an anticancer drug candidate currently in clinical trials. TAS-102 consists of the cytotoxin Trifluridine and the thymidine phosphorylase inhibitor (TPI) tipiracil. Trifluridine is incorporated into DNA during DNA synthesis and inhibits tumor cell growth. Tipiracil protects trifluridine from being broken down when taken orally. Synonyms: Tipiracil, TPI. Grades: 0.99. CAS No. 183204-72-0. Molecular formula: C9H12Cl2N4O2. Mole weight: 279.121. | |
| Tiplaxtinin | Tiplaxtinin is a novel plasminogen activator inhibitor-1 (PAI-1) inhibitor. It is an orally active prothrombolytic drug that inhibits PAI-1 and accelerates fibrinolysis while maintaining normal coagulation in a model of coronary occlusion. It exerts antithrombotic efficacy in rat models of arterial and venous vascular injury without effecting platelet aggregation. Synonyms: Tiplaxtinin; PAI039; PAI-039; PAI 039. Grades: >98%. CAS No. 393105-53-8. Molecular formula: C24H16F3NO4. Mole weight: 439.38. | |
| Tirapazamine | Tirapazamine is a benzotriazine di-N-oxide with potential antineoplastic activity. Tirapazamine is selectively activated by multiple reductases to form free radicals in hypoxic cells, thereby inducing single-and double-strand breaks in DNA, base damage, and cell death. This agent also sensitizes hypoxic cells to ionizing radiation and inhibits the repair of radiation-induced DNA strand breaks via inhibition of topoisomerase II. Check for active clinical trials or closed clinical trials using this agent. Synonyms: US brand name: Tirazone. Code names: SR 4233. WIN 59075. SR-259075, NSC-130181, Win-59075, SR-4233. Grades: 0.98. CAS No. 27314-97-2. Molecular formula: C7H6N4O2. Mole weight: 178.15. | |
| Tirofiban Hydrochloride Monohydrate | Tirofiban is a specific nonpeptide platelet fibrinogen receptor (GPIIb/IIIa) antagonist. Tirofiban is an antithrombotic used in the treatment of unstable angina. Uses: The treatment of unstable angina. Synonyms: N-(Butylsulfonyl)-4-(4-(4-piperidyl)butoxy)-L-phenylalanine monohydrochloride monohydrate; Aggrastat; L 700462; L700462; L-700,462; MK-383; MK 383; MK383; Tirofiban; Tirofiban hydrochloride monohydrate. Grades: >98%. CAS No. 150915-40-5. Molecular formula: C22H39ClN2O6S. Mole weight: 495.07. | |
| Tirofiban Impurity C | One of the impurities of Tirofiban, which has been found to be a glycoprotein IIb/IIIa inhibitor and could be used as an antiplatelet agent. Synonyms: N-(n-Butanesulfonyl)-O-[4-(4-pyridinyl)-butyl]-(S)-tyrosine; 2-(Butane-1-sulfonylamino)-3-[4-(4-pyridin-4-yl-butoxy)-phenyl]-popionic Acid. CAS No. 149490-61-9. Molecular formula: C22H30N2O5S. Mole weight: 434.56. | |
| Tivozanib | Tivozanib is an orally bioavailable inhibitor of vascular endothelial growth factor receptors (VEGFRs) 1, 2 and 3 with potential antiangiogenic and antineoplastic activities. Tivozanib binds to and inhibits VEGFRs 1, 2 and 3, which may result in the inhibition of endothelial cell migration and proliferation, inhibition of tumor angiogenesis and tumor cell death. VEGFR tyrosine kinases, frequently overexpressed by a variety of tumor cell types, play a key role in angiogenesis. Check for active clinical trials or closed clinical trials using this agent. Synonyms: AV-951; AV951; AV 951; KRN951; KRN 951; KRN-951. Grades: 0.98. CAS No. 475108-18-0. Molecular formula: C22H19ClN4O5. Mole weight: 454.86306. | |
| Tizanidine hydrochloride | Tizanidine is an α2-adrenergic receptor agonist and inhibits neurotransmitter release from CNS noradrenergic neurons. Synonyms: Tizanidine HCl; Zanaflex; Sirdalud; 5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine hydrochloride. Grades: >98%. CAS No. 64461-82-1. Molecular formula: C9H8ClN5S·HCl. Mole weight: 290.17. | |
| Tizoxanide | Tizoxanide is the active metabolite of nitazoxanide, an anti-infective that has been approved for the treatment of diarrhea caused by Giardia lamblia or Crytosporidium parvum. Tizoxanide is active against anaerobic bacteria, protozoan parasites, and viruses. It reduces the growth of the disease-causing parasites, L. mexicana and T. cruzi, in vitro (IC50s = 6.2 and 17.5 μM, respectively), inhibits influenza A replication (EC50s = 0.3-1 μM)3, and inhibits hepatitis B and hepatitis C virus replication (EC50s both=0.15 μM). Uses: Anti-infective agents. Synonyms: TIZ; NSC-697856; NSC697856; NSC697856; Tizoxanide; Desacetylnitazoxanide; Desacetyl-nitazoxanide. Grades: >98%. CAS No. 173903-47-4. Molecular formula: C10H7N3O4S. Mole weight: 265.25. | |
| TLR7/8 agonist 1 | TLR7/8 agonist 1 is a dual agonist of toll-like receptor 7 (TLR7) and TLR8. It exhibits prominent immunostimulatory activities. CAS No. 1258457-59-8. Molecular formula: C22H25N5. Mole weight: 359.5. | |
| TLR7/8 agonist 1 dihydrochloride | TLR7/8 agonist 1 is a dual agonist of toll-like receptor 7 (TLR7) and TLR8. It exhibits prominent immunostimulatory activities. Synonyms: TLR7/8 agonist 1 hydrochloride. CAS No. 1620278-72-9. Molecular formula: C22H27Cl2N5. Mole weight: 432.4. | |
| TM-5275 sodium salt | TM-5275 sodium salt is an orally bioavailable, potent and selective plasminogen activator inhibitor-1 (PAI-1). It delivers antithrombotic benefits devoid of bleeding effect in nonhuman primates. Uses: Tm-5275 sodium salt delivers antithrombotic benefits devoid of bleeding effect in nonhuman primates. Synonyms: TM5275 sodium salt; TM 5275 sodium salt; TM-5275 sodium salt; 5-Chloro-2-[[2-[2-[4-(Diphenylmethyl)-1-piperazinyl]-2-oxoethoxy]acetyl]amino]benzoic acid sodium salt; Sodium 2-[[2-[2-(4-benzhydrylpiperazin-1-yl)-2-oxoethoxy]acetyl]amino]-5-chlorobenzoate. Grades: >98%. CAS No. 1103926-82-4. Molecular formula: C28H27ClN3NaO5. Mole weight: 543.98. | |
| TNF-α (46-65), human | TNF-α (46-65), human is a compound accomplishing its efficacy by specifically targeting a fragment of Tumor Necrosis Factor-alpha (TNF-α), finding purpose in the studyof diverse conditions, encompassing rheumatoid arthritis, psoriasis, Crohn's disease and ulcerative colitis. Synonyms: H-Asn-Gln-Leu-Val-Val-Pro-Ser-Glu-Gly-Leu-Tyr-Leu-Ile-Tyr-Ser-Gln-Val-Leu-Phe-Lys-OH. Grades: 98%. CAS No. 144796-72-5. Molecular formula: C110H172N24O30. Mole weight: 2310.69. | |
| TNO155 | TNO155 is an inhibitor of protein tyrosine phosphatase (PTP) non-receptor type 11 (SHP2; src homology region 2 domain phosphatase; PTPN11), with potential antineoplastic activity. Synonyms: TNO-155; TNO 155. Grades: 98%. CAS No. 1801765-04-7. Molecular formula: C18H24ClN7OS. Mole weight: 421.948. | |
| Toceranib phosphate | Toceranib phosphate is a kinase inhibitor with both antitumor and antiangiogenic activity through inhibition of KIT, vascular endothelial growth factor receptor 2, and PDGFR&beta. It is a receptor tyrosine kinase inhibitor and is used in the treatment of canine mast cell tumor also called mastocytoma. It may also have an anti-angiogenic effect. Synonyms: SU 11654; PHA 291639; SU11654; SU-11654; PHA-291639; PHA291639. Grades: >98%. CAS No. 874819-74-6. Molecular formula: C22H28FN4O6P. Mole weight: 494.45. | |
| Tocofersolan | Tocofersolan is a synthetic water-soluble vitamin E, which is an alpha tocopherol derivative used to treat vitamin E deficiency. Synonyms: [2R-[2R*(4R*,8R*)]]-α-[4-[[3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl]oxy]-1,4-dioxobutyl]-ω-hydroxypoly(oxy-1,2-ethanediyl); D-α-Tocopherol Polyethylene Glycol 1000 Succinate; Vitamin E Polyethylene Glycol Succinate; Mono[2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-6-chromanyl] Succinate Polyoxyethylene Ether; TPGS; Tocophersolan; Vitamin E-TPGS. Grades: 96%. CAS No. 9002-96-4. Molecular formula: C33H53O4(C2H5O2)n. | |
| Tocopherol Impurity 1 | One of the impurities of Vitamin E, which has been found to exhibit antioxidant activity. Synonyms: 2H-1-Benzopyran-6-ol, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-. CAS No. 3808-26-2. Molecular formula: C29H48O2. Mole weight: 428.69. | |
| Tocopherols | Synonyms: AT 160; BK 801; Controx VP; Copherol F 1300; Covi-Ox T 30P; Covi-Ox T 50; Covi-Ox T 70; Covi-Ox T 7OC; Covi-ox T 90; Covi-Ox T 90EU-C; CoviOx; Decanox MTS 50; Dry E-Mix 20; E 306; E-Mix 35L; E-Mix 40A; E-Mix 60; E-Mix 80; E-Mix P 20; E-Oil 600; E-Oil 700; E-Oil 705; E-Oil 800; E-Oil 805D; E-Oil Super 60; Fortium MTD 10; Golden Tocopherol 70; Grindox 497; Irganox E 217DF; MTS 60S; Oxynat 70IP; Riken Dry E-Mix SP-T; Riken E Oil 600N; Riken E Oil 700; Riken E Oil Super 80G; Riken E-Emulsion; Riken E-Oil 705; Riken E-Oil 710; Riken E-Oil 900α; Riken E-Oil Super 60; Riken E-Oil Super 80; Riken Oil Super 80; Rikki N 70; Tenox GT; Tocoblend L 50IP; Tocolit Powder 30; Tocomix L 70; Tocopherol; Tocopherol 80; Tocovet; Tocovet E 1000; Tocovet M 90; Tokomikkusu 500. CAS No. 1406-66-2. | |
| Tofacitinib N-Oxide | Tofacitinib N-Oxide is an impurity of Tofacitinib, which is a Janus kinase inhibitor and could be used against rheumatoid arthritis. Synonyms: Tofacitib related impuritie 8; 1-Piperidinepropanenitrile, 4-methyl-3-(methyloxido-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-β-oxo-, (3R,4R)-. Grades: ≥95%. CAS No. 2028267-73-2. Molecular formula: C16H20N6O2. Mole weight: 328.37. | |
| Tofogliflozin hydrate | Tofogliflozin(CSG-452) hydrate is a potent and highly specific sodium/glucose cotransporter 2(SGLT2) inhibitor with Ki values of 2.9, 14.9, and 6.4 nM for human, rat, and mouse SGLT2. Synonyms: CSG452 hydrate; CSG-452 hydrate; CSG 452 hydrate. Grades: >98%. CAS No. 1201913-82-7. Molecular formula: C22H28O7. Mole weight: 404.45. | |
| Tolcapone | Tolcapone functions as a selective peripheral and central COMT inhibitor, exerting no effect on adrenergic, serotonergic, or cholinergic receptors or other enzymes involved in synthesis or catabolism of catecholamines. Synonyms: Ro 40-7592; Ro40-7592; Ro-40-7592. Grades: >98%. CAS No. 134308-13-7. Molecular formula: C14H11NO5. Mole weight: 273.24. | |
| Tolfenpyrad | Tolfenpyrad is used as foliar insecticide for the control of green peach aphids in broccoli. Synonyms: 4-Chloro-3-ethyl-1-methyl-N-[[4-(4-methylphenoxy)phenyl]methyl]-1H-pyrazole-5-carboxamide; Tolfenpyrad; Hachihachi EC; NAI 2302; NAI-2302; NAI2302; NAI 2303; OMI 88; OMI-88; OMI88. Grades: >98%. CAS No. 129558-76-5. Molecular formula: C21H22ClN3O2. Mole weight: 383.87. | |
| Torin 2 | Torin 2 is a potent and selective mTOR inhibitor with IC50 of 2.1 nM. It inhibits ATM/ATR/DNA-PK with EC50 of 28 nM/35 nM/118 nM, in PC3 cell lines respectively. It is potentially used as an antineoplastic agent. Synonyms: Torin-2; Torin2; Torin 2; 9-(6-aminopyridin-3-yl)-1-[3-(trifluoromethyl)phenyl]benzo[h][1, 6]naphthyridin-2-one. Grades: 98%. CAS No. 1223001-51-1. Molecular formula: C24H15F3N4O. Mole weight: 432.406. | |
| Tosedostat | Tosedostat is an aminopeptidase inhibitor for LAP, PuSA and Aminopeptidase N with IC50 of 100 nM, 150 nM and 220 nM, respectively, and does not effectively inhibit either PILSAP, MetAP-2, LTA4 hydrolase, or MetAP-2 with IC50 values are > 1000, > 5000, > 10000 and > 30000 nM for aminopeptidase B, PILSAP, LTA4 hydrolase and MetAP2 respectively. Phase 2. Tosedostat potently inhibits tumor cell proliferation in a variety of tumor cell lines in vitro and in vivo. Synonyms: CHR2797; CHR-2797; CHR 2797; Tosedostat. cyclopentyl (2S)-2-[[(2R)-2-[(1S)-1-hydroxy-2-(hydroxyamino)-2-oxoethyl]-4-methylpentanoyl]amino]-2-phenylacetate. Grades: 98%. CAS No. 238750-77-1. Molecular formula: C21H30N2O6. Mole weight: 406.479. | |
| Tozasertib | The Aurora kinases (A, B, and C) are a family of serine-threonine kinases that regulate various stages of mitotic function. With significant roles in cell cycle and cell division, Aurora kinase gene amplification and overexpression are linked to tumorigenesis. MK 0457 is a potent pan-Aurora kinase inhibitor but favors Aurora A (Ki = 0.6 nM) over Aurora B (Ki = 18 nM) or Aurora C (Ki = 4.6 nM). It shows selectivity against a panel of more than 190 different protein kinases. MK 0457 effectively inhibits proliferation of several different cell lines of clear cell renal carcinoma (IC50s < 10 μM) and blocks the growth of tumors in a rodent model of cancer (80 mg/kg), inhibiting histone H3 phosphorylation and increasing apoptosis. By depleting Aurora activity, MK 0457 disrupts bipolar spindle formation during mitosis, arresting cell cycle progression at the G2/M phase. Synonyms: VX680; VX 680; VX-680; MK0457; MK 0457; MK-0457; VE465; VE-465; VE 465; Tozasertib. CAS No. 639089-54-6. Molecular formula: C23H28N8OS. Mole weight: 464.59. | |
| TP 064 | TP 064 is a potent and selective PRMT4 inhibitor with >100-fold selectivity over other histone methyltransferases and non-epigenetic targets. TP 064 inhibits methylation of H3 (1-25) and MED12 in cellular assays (IC50 values are <10 and 43 nM, respectively). Synonyms: TP-064; TP064; N-Methyl-N-((2-(1-(2-(methylamino)ethyl)piperidin-4-yl)pyridin-4-yl)methyl)-3-phenoxybenzamide. Grades: ≥98% by HPLC. CAS No. 2080306-20-1. Molecular formula: C28H34N4O2. Mole weight: 458.6. | |
| TP-0903 | TP-0903 is a potent anti-cancer agent targeting the AXL receptor tyrosine kinase that has demonstrated profound activity in several cell-based and animal models of cancer. Uses: For research use only. Synonyms: TP-0903; TP 0903; TP0903. Grades: >98%. CAS No. 1341200-45-0. Molecular formula: C24H30ClN7O2S. Mole weight: 516.06. | |
| TP-10 | TP-10 is a PDE10A inhibitor with IC50 of 0.8 nM. It has extremely potent PDE10A inhibitory activity and high selectivity against other PDEs. It is active in the mouse behavioral model for positive symptoms. It demonstrats good in vitro and in vivo activity. Synonyms: TP-10; TP 10; TP10; 2-{4-[4-Pyridin-4-yl-1-(2,2,2-trifluoro-ethyl)-1H-pyrazol-3-yl]-phenoxymethyl}-quinoline;Substituted pyrazole, 13;2-[[4-[4-pyridin-4-yl-1-(2,2,2-trifluoroethyl)pyrazol-3-yl]phenoxy]methyl]quinoline. Grades: >98%. CAS No. 898563-00-3. Molecular formula: C26H19F3N4O. Mole weight: 460.45. | |
| TPCA-1 | TPCA-1 is an inhibitor of IKK-2 with IC50 of 17.9 nM and 0.40 μM for IKK-1 and IKK-2 respectively. It blocks NF-κB pathway and STAT3 activity. Synonyms: TPCA1; TPCA 1; 5-(4-Fluorophenyl)-2-ureidothiophene-3-carboxamide; IKK-2 Inhibitor IV. Grades: >98%. CAS No. 507475-17-4. Molecular formula: C12H10FN3O2S. Mole weight: 279.29. | |
| TPT-260 2HCl | TPT-260 2HCl is a thiophene thiourea derivative that acts as a chaperone to stabilize the retromer complex against thermal denaturation. Synonyms: TPT-260 Dihydrochloride; TPT-260 (Dihydrochloride); Thiophene-2,5-diylbis(methylene) dicarbamimidothioate dihydrochloride; [5- (Carbamimidoylsulfanylmethyl) thiophen-2-yl]methyl carbamimidothioate dihydrochloride. Grades: 98%. CAS No. 2076-91-7. Molecular formula: C8H14Cl2N4S3. Mole weight: 333.32. | |
| Tralonide | Synonyms: 9,11β-Dichloro-6α,21-difluoro-16α,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione. Grades: > 95%. CAS No. 21365-49-1. Molecular formula: C24H28Cl2F2O4. Mole weight: 489.39. | |
| (-)-trans 3'-Aminomethyl Nicotine | (-)-trans 3'-Aminomethyl Nicotine is one of Nicotine derivatives, which is a potent parasympathomimetic stimulant. Synonyms: 3-Pyrrolidinemethanamine, 1-methyl-2-(3-pyridinyl)-, (2S,3R)-; (2S,3R)-1-Methyl-2-(3-pyridinyl)-3-pyrrolidinemethanamine; (2S,3R)-1-Methyl-2-(3-pyridyl)pyrrolidine-3-methanamine; 1-[(2S,3R)-1-Methyl-2-(3-pyridinyl)-3-pyrrolidinyl]methanamine. CAS No. 272124-60-4. Molecular formula: C11H17N3. Mole weight: 191.27. | |
| (trans)-3-((benzo[d][1,3]dioxol-5-yloxy)methyl)-4-(4-methoxyphenyl)-1-methylpiperidine hydrochloride | An impurity of Paroxetine which is a selective serotonin reuptake inhibitor. Synonyms: Paroxetine Impurity 40. CAS No. 127017-41-8. Molecular formula: C21H26ClNO4. Mole weight: 391.89. | |
| trans-3-Hydroxy Cotinine | Cas No. 34834-67-8. | |
| trans-4,5-dichloro-4,5-dimethyl-1,3-dioxolan-2-one | Trans-4,5-Dichloro-4,5-dimethyl-1,3-dioxolan-2-one is a dioxolone derivative used in the preparation of various prodrugs. Synonyms: trans-4,5-Dichloro-4,5-dimethyl-1,3-dioxolan-2-one; 116857-05-7. Grades: > 95%. CAS No. 116857-05-7. Molecular formula: C5H6Cl2O3. Mole weight: 185.01. | |
| trans-4-Aminocyclohexanol Hydrochloride | An impurity of Ambroxol. Synonyms: trans-4-Hydroxycyclohexylamine hydrochloride. Grades: > 95%. CAS No. 50910-54-8. Molecular formula: C6H13NO. HCl. Mole weight: 151.63. | |
| (trans) -4- ( ( (trans) -4- (aminomethyl) cyclohexanecarboxamido) methyl) cyclohexanecarboxylic acid hydrochloride | Cas No. 157605-44-2. Molecular formula: C16H29ClN2O3. Mole weight: 332.87. | |
| trans-Cypermethrin Benzaldehyde | trans-Cypermethrin Benzaldehyde is an impurity of Cypermethrin, which is a synthetic pyrethroid used as an insecticide. Synonyms: 2-Oxo-1-(3-phenoxyphenyl)-2-phenylethyl (1R,3S)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate; trans-Cypermethrin Impurity; (1R,3S)-2-Oxo-1-(3-phenoxyphenyl)-2-phenylethyl 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate; Cyclopropanecarboxylic acid, 3-(2,2-dichloroethenyl)-2,2-dimethyl-, 2-oxo-1-(3-phenoxyphenyl)-2-phenylethyl ester, (1R,3S)-. Molecular formula: C28H24Cl2O4. Mole weight: 495.39. | |
| trans-doxercalciferol | Trans-doxercalciferol is an isomer of doxercalciferol, a drug used for the treatment of secondary hyperparathyroidism and metabolic bone disease. Synonyms: (5E,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraene-1α,3β-diol. CAS No. 74007-20-8. Molecular formula: C28H44O2. Mole weight: 412.658. | |
| Trans-Fluvoxamine | Grades: > 95%. CAS No. 39-18-3. Molecular formula: C15H21F3N2O2. Mole weight: 318.34. | |
| trans-maxacalcitol | Trans-maxacalcitol is an isomer of maxacalcitol, a derivative of vitamin D3. Maxacalcitol is a potential treatment of secondary hyperparathyroidism. Synonyms: Impurity A of Maxacalcitol. CAS No. 929721-98-2. Molecular formula: C26H42O4. Mole weight: 418.6. | |
| trans-Permethrin | trans-Permethrin is the trans-isomer of Permethrin, which is a medication and an insecticide used to treat scabies and lice. Synonyms: (±)-trans-Permethrin; 1RS,trans-Permethrin; NRDC 146; trans-m-Phenoxybenzyl 3-(2,2-Dichlorovinyl-2,2-dimethylcyclopropanecarboxylate; trans-3-(2,2-Dichloroethenyl)-2,2-dimethyl-cyclopropanecarboxylic Acid (3-Phenoxyphenyl)methyl ester; Biopermethrin. Grades: 98%. CAS No. 61949-77-7. Molecular formula: C21H20Cl2O3. Mole weight: 391.29. | |
| Tranylcypromine hydrochloride | Tranylcypromine is a monoamine oxidase inhibitor, which inhibits CYP2A6 with Ki of 0.08 μM and 0.2 μM in cDNA-expressing microsomes and human liver microsomes, respectively. Synonyms: (1R,2S)-2-phenylcyclopropan-1-amine;hydrochloride. Grades: > 98 %. CAS No. 1986-47-6. Molecular formula: C9H12ClN. Mole weight: 169.65. | |
| Trapidil | Trapidil, also called as Rocornal, is a platelet aggregation inhibitor with specific platelet-derived growth factor. Uses: Vasodilator agents. Synonyms: N,N-diethyl-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-aminerapidilRocornalTrapymin15421-84-8AvantrinTrapymineTrapidil; AR 12008; AR-12008; AR12008Trapidilum [INN-Latin]UNII-EYG5Y6355EMLS000567667N,N-diethyl-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amineEINECS 239-434-2. CAS No. 15421-84-8. Molecular formula: C10H15N5. Mole weight: 205.26. | |
| Travoprost | Travoprost is a potent and selective FP prostaglandin receptor agonist used for the treatment of glaucoma. Synonyms: Travatan; Fluprostenol isopropyl ester; AL-6221; Flu-Ipr. Grades: >98%. CAS No. 157283-68-6. Molecular formula: C26H35F3O6. Mole weight: 500.55. | |
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