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Icaritin
Icaritin is unable to promote proliferation, migration and tube-like structure formation by human umbilical vein endothelial cells (HUVECs) in vitro. Icaritin potently inhibited proliferation of K562 cells (IC50 was 8 μM) and primary CML cells (IC50 was 13.4 μM for CML-CP and 18 μM for CML-BC), induced CML cells apoptosis and promoted the erythroid differentiation of K562 cells with time-dependent manner. Furthermore, Icaritin was able to suppress the growth of primary CD34+ leukemia cells (CML) and Imatinib-resistant cells, and to induce apoptosis. Icaritin strongly inhibited the growth of breast cancer MDA-MB-453 and MCF7 cells. At concentrations of 2-3 μM, icaritin induced cell cycle arrest at the G(2)/M phase accompanied by a down-regulation of the expression levels of the G(2)/M regulatory proteins such as cyclinB, cdc2 and cdc25C. Icaritin at concentrations of 4-5 μM, however, induced apoptotic cell death characterized by the accumulation of the annexin V- and propidium iodide-positive cells, cleavage of poly ADP-ribose polymerase (PARP) and down-regulation of the Bcl-2 expression. In mouse leukemia model, Icaritin could prolong lifespan of NOD-SCID nude mice inoculated with K562 cells as effective as Imatinib without suppression of bone marrow. Icaritin could up-regulate phospho-JNK or phospho-C-Jun and down-regulate phospho-ERK, phospho-P-38, Jak-2, phospho-Stat3 and phospho-Akt expression with dose- or ti
i-Carradecaitoldecasulfate decasodium salt
i-Carradecaitoldecasulfate decasodium salt is a groundbreaking biomedical compound which can inhibit designated enzymes responsible for exacerbating cancer cell proliferation. It aids in studying lung, breast and prostate malignancies. Molecular formula: C60H84O72S10Na10. Mole weight: 2507.82.
i-Carrahexaitol hexasulfate hexasodium salt
i-Carrahexaitol hexasulfate hexasodium salt is a derivative derived from i-Carrahexaitol, offering unprecedented opportunities for studying a multitude of diseases and conditions such as drug-resistant cancers and inflammatory disorders. Synonyms: Iota-Carrahexaitol-Hexasulfate Hexasodium Salt. Molecular formula: C36H52O44S6Na6. Mole weight: 1519.11.
i-Carrahexaose hexasulfate hexasodium salt
i-Carrahexaose hexasulfate hexasodium salt, an innovative biomedical substance, stands as a formidable solution against an array of ailments. By virtue of its unrivaled chemical configuration, it exhibits an outstanding capacity to impede the replication of notorious infectious agents such as HIV, influenza, and herpes viruses. Moreover, this extraordinary therapeutic treasure finds application in tackling inflammatory disorders and combating cancer. Synonyms: Iota-Carrahexaose-Hexasulfate Hexasodium Salt. Molecular formula: C36H50O43S6Na6. Mole weight: 1501.09.
i-Carraoctaitol octasulfate octasodium salt
i-Carraoctaitol octasulfate octasodium salt, an eminent biomedicine product, distinguishes itself as a paramount entity employed in the amelioration of diverse maladies. Exhibiting efficacy across ailments such as cancer, cardiovascular disorders, and inflammatory diseases, this multifaceted compound assumes the role of a commendable therapeutic intervention. Synonyms: Iota-Carraoctaitol 12,24,32,44,52,64,72,84-octasulfate octasodium salt; Iota-Carraoctaitol-Octasulfate Octasodium Salt. Molecular formula: C48H68O58S8Na8. Mole weight: 2013.46.
i-Carratetraitol tetrasulfate tetrasodium salt
i-Carratetraitol tetrasulfate tetrasodium salt is an extraordinary pharmaceutical compound extensively employed in the biomedical sphere. This exceptional substance showcases unparalleled efficiency in studying enduring inflammatory ailments, such as arthritand asthma. Synonyms: Iota-Carratetraitol-Tetrasulfate Tetrasodium Salt. Molecular formula: C24H36O30S4Na4. Mole weight: 1024.75.
i-Carratetraose tetrasulfate tetrasodium salt
i-Carratetraose tetrasulfate tetrasodium salt is a potent biomedical compound used in the treatment of various inflammatory conditions and autoimmune diseases. It exhibits excellent anti-inflammatory properties by effectively inhibiting the activation of pro-inflammatory cytokines. This product acts as a therapeutic agent to alleviate symptoms associated with conditions such as rheumatoid arthritis and Crohn's disease while promoting immune modulation. Synonyms: Iota-Carratetraose-Tetrasulfate Tetrasodium Salt. Molecular formula: C24H34O29S4Na4. Mole weight: 1006.73.
I-CBP 112
I-CBP112 has been found to be a CBP/p300 bromodomain inhibitor and could reduce the leukemia-initiating potential of MLL-AF9(+) acute myeloid leukemia cells. Synonyms: I-CBP112; I-CBP-112; I-CBP 112. 1-[7-(3,4-Dimethoxyphenyl)-9-[[(3S)-1-methylpiperidin-3-yl]methoxy]-2,3,4,5-tetrahydro-1,4-benzoxazepin-4-yl]propan-1-one. Grade: ≥98% by HPLC. CAS No. 1640282-31-0. Molecular formula: C27H36N2O5. Mole weight: 468.59.
I-CBP112 hydrochloride
I-CBP112 is a selective inhibitor of CBP and EP300 bromodomain (Kds = 0.142 and 0.625 μM, respectively). CBP and EP300 are histone acetyltransferase (HAT) enzymes that serve as transcriptional coactivators and have been found to be dysregulated in cancer and other diseases. Synonyms: 1-[7-(3,4-dimethoxyphenyl)-9-[[(3S)-1-methylpiperidin-3-yl]methoxy]-3,5-dihydro-2H-1,4-benzoxazepin-4-yl]propan-1-one hydrochloride. Grade: ≥90%. CAS No. 2147701-33-3. Molecular formula: C27H36N2O5·HCl. Mole weight: 505.1.
ICCB-19 hydrochloride
ICCB-19 hydrochloride is an inhibitor of TNFRSF1A Associated Via Death Domain (TRADD). ICCB-19 indirectly inhibits Receptor-interacting serine/threonine-protein kinase 1 (RIPK1). Synonyms: N-cycloheptyl-2-(4,5-dihydro-1H-imidazol-2-ylsulfanyl)acetamide hydrochloride. CAS No. 1803605-68-6. Molecular formula: C12H22ClN3OS. Mole weight: 291.84.
ICCB280
ICCB280 is a potent inducer of C/EBPα. ICCB280 exhibits anti-leukemic properties including terminal differentiation, proliferation arrest, and apoptosis through activation of C/EBPα and affecting its downstream targets (such as C/EBPε, G-CSFR and c-Myc). Synonyms: (E)-2-(3,4-Dihydroxystyryl)-3-(2-methoxyphenyl)quinazolin-4(3H)-one. Grade: 98%. CAS No. 2041072-41-5. Molecular formula: C23H18N2O4. Mole weight: 386.40.
ICEC-0942
ICEC-0942 is a small-molecule cyclin-dependent kinase 7 (CDK7) inhibitor developed for cancer therapy. Preclinical study in Acute Myeloid Leukaemia (AML) models shows that ICEC-0942 effectively inhibits the proliferation of several AML cell lines and patient derived AML cells in vitro (IC50 = 0.15-2.6 μM). Uses: Anticancer drug. Synonyms: CT7001; CT 7001; CT-7001; ICEC0942; ICEC0 942; ICEC0-942. CAS No. 1805833-75-3. Molecular formula: C22H30N6O. Mole weight: 394.52.
Icenticaftor
Icenticaftor is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator, which can be used for the treatment of chronic obstructive pulmonary disease (COPD) and cystic fibrosis. Synonyms: NVP-QBW251; QBW251. CAS No. 1334546-77-8. Molecular formula: C12H13F6N3O3. Mole weight: 361.24.
ICG-001
ICG-001 is an antagonist of Wnt/β-catenin/TCF-mediated transcription and binds to cyclic AMP responsive element binding-binding protein (CBP)-mediated transcription with IC50 value of 3 μM. ICG-001 has been demonstrated to inhibit gastric cancer cell growth and reduce chemoresistance of cancer stem cell-like population. Synonyms: ICG 001; (6S,9aS)-N-benzyl-6-[(4-hydroxyphenyl)methyl]-8-(naphthalen-1-ylmethyl)-4,7-dioxo-3,6,9,9a-tetrahydro-2H-pyrazino[1,2-a]pyrimidine-1-carboxamide. Grade: >98%. CAS No. 780757-88-2. Molecular formula: C33H32N4O4. Mole weight: 548.63.
ICI-118551 HCl
A highly selective antagonist for the β2 adrenergic receptors. Binds to the β2 subtype with at least 100 times greater affinity than β1 or β3, the two other known subtypes of the beta adrenoceptor. (Ki values are 1.2, 120 and 257 nM for β2, β1 and β3 receptors respectively). Synonyms: ICI-118551; ICI118551; ICI 118551; ICI-118,551; ICI118,551; ICI 118,551. Grade: 98%. CAS No. 72795-19-8. Molecular formula: C17H28ClNO2. Mole weight: 313.866.
ICI 118551 hydrochloride
ICI 118551 hydrochloride is a highly selective β2 adrenergic antagonist (Ki values are 1.2, 120 and 257 nM for β2, β1 and β3 receptors respectively), inhibited cAMP accumulation by 50% (IC50 = 1.5 microM and 1.7 microM, respectively). Uses: A highly selective β2 adrenergic receptor antagonist. Synonyms: ICI 118551 hydrochloride; ICI118551 hydrochloride; ICI-118551 hydrochloride; (±)-erythro-(S*,S*)-1-[2,3-(Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanol hydrochloride; (2R,3S)-1-[(7-methyl-2,3-dihydro-1H-inden-4-yl)oxy]-3-(propan-2-ylamino)butan-2-ol; hydrochloride. Grade: ≥98%. CAS No. 72795-01-8. Molecular formula: C17H27NO2.HCl. Mole weight: 313.86.
ICI141292
ICI141292, also known as Epanolol, is a adrenergic β-antagonist with a greater affinity for β1- than β2-adrenoceptors, which is used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety. Synonyms: N-[2-[[3-(2-cyanophenoxy)-2-hydroxypropyl]amino]ethyl]-2-(4-hydroxyphenyl)acetamide; epanolol; ICI 141,292; ICI 141292; ICI-141,292; N-(2-((3-(2-cyanophenoxy)-2-hydroxypropyl)amino)ethyl)-4-hydroxyphenylacetamide; Visacor. CAS No. 86880-51-5. Molecular formula: C20H23N3O4. Mole weight: 369.41.
ICI 162,846
ICI 162,846 is a potent histamine H2 receptor antagonist. Synonyms: ICI 162,846; ICI162,846; ICI-162,846; N-[1-(4-Carboxamidobutyl)-1H-pyrazol-3-yl)]-N'-(2,2,2-trifluoroethyl)guanidine; 3-[[Imino[(2,2,2-trifluoroethyl)amino]methyl]amino]-1H-pyrazole-1-pentanamide. CAS No. 84545-30-2. Molecular formula: C11H17F3N6O. Mole weight: 306.29.
ICI 185,282
ICI 185,282 is a potent thromboxane receptor antagonist. Synonyms: ICI-185282; ICI 185282; ICI185282; 5-(Z)-7-(4-o-Hydroxyphenyl-2-trifluoromethyl-1,3 dioxan-cis-5-yl)heptenoic acid. CAS No. 106393-80-0. Molecular formula: C18H21F3O5. Mole weight: 374.36.
ICI 192,605
ICI 192,605 is a potent thromboxane A2 receptor antagonist. It can reverse vasoconstriction induced by inhibition of NO production and inhibits platelet aggregation, which leads to an increase in TXA2 release. It also inhibits contractile responses to U 46619. Synonyms: ICI 192605 ; ICI192605; ICI-192605. (4Z)-rel-, 4(Z)-6-(2-o-chlorophenyl-4-o-hydroxyphenyl-1,3-dioxan-cis-5-yl) hexenoic acid; 4-Hexenoic acid, 6-[(2R,4R,5S)-2-(2-chlorophenyl)-4-(2-hydroxyphenyl)-1,3-dioxan-5-yl]-; 4-(Z)-6-(2-o-Chlorophenyl-4-o-hydroxyphenyl-1,3-dioxan-cis-5-yl)hexenoic acid; (E)-6-[(2S,4S,5R)-2-(2-chlorophenyl)-4-(2-hydroxyphenyl)-1,3-dioxan-5-yl]hex-4-enoic acid; rel-(4Z)-6-[(2R,4R,5S)-2-(2-Chlorophenyl)-4-(2-hydroxyphenyl)-1,3-dioxan-5-yl]-4-hexenoic Acid. Grade: ≥98% by HPLC. CAS No. 117621-64-4. Molecular formula: C22H23ClO5. Mole weight: 402.87.
ICI-198615
ICI-198615 is a novel, potent and selective peptide leukotriene antagonist. It may be useful for the the treatment of allergic diseases. Uses: Ici-198615 may be useful for the the treatment of allergic diseases. Synonyms: [1-[[2-Methoxy-4-[[(phenylsulfonyl)amino]carbonyl]phenyl]methyl]-1H-indazol-6-yl]carbamic acid cyclopentyl ester; Cyclopentyl N-[1-[[4-(benzenesulfonylcarbamoyl)-2-methoxyphenyl]methyl]indazol-6-yl]carbamate; ICI 198615; ICI-198615; ICI198615; ICI-198,615; ZM 198615; ZM-198615. Grade: >98 %. CAS No. 104448-53-5. Molecular formula: C28H28N4O6S. Mole weight: 548.61.
ICI 199,441 hydrochloride
ICI 199,441 hydrochloride is the hydrochloride salt of ICI 199,441, which is a selective and highly potent κ agonist. It is 146-fold more active than U-50488 in vitro. It has a broad range of effects on the immune system ranging from inflammatory response modulation to opioid and chemokine receptor expression. It has analgesic properties. Synonyms: ICI 199,441 hydrochloride; ICI199,441 hydrochloride; ICI-199,441 hydrochloride; 3,4-Dichloro-N-methyl-N-[(1S)-1-phenyl-2-(1-pyrrolidinyl)ethyl]-benzeneacetamide Monohydrochloride; (S)-3,4-Dichloro-N-methyl-N-[1-phenyl-2-(1-pyrrolidinyl)ethyl]-benzeneacetamide Monohydrochloride; 2-(3,4-Dichlorophenyl)-N-methyl-N-[(1S)-1-phenyl-2-(1-pyrrolidinyl)ethyl]acetamide hydrochloride. Grade: ≥99% by HPLC. CAS No. 115199-84-3. Molecular formula: C21H25Cl3N2O. Mole weight: 427.80.
ICI 204,448 hydrochloride
ICI 204,448 hydrochloride is the hydrochloride salt of ICI 204,448, which is a peripherally acting κ opioid receptor agonist. It does not cross the blood-brain barrier. Synonyms: ICI 204,448 hydrochloride; ICI204,448 hydrochloride; ICI-204,448 hydrochloride; (±)-1-[2,3-(Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanol hydrochloride; (RS)-[3-[1-[[(3,4-Dichlorophenyl)acetyl]methylamino]-2-(1-pyrrolidinyl)ethyl]phenoxy]acetic acid hydrochloride. Grade: ≥98% by HPLC. CAS No. 121264-04-8. Molecular formula: C23H27Cl3N2O4. Mole weight: 501.84.
ICI 211965
ICI 211965 is a selective 5-lipoxygenase inhibitor and it may be useful in regulating production of those interleukins involved in joint cartilage destruction. Synonyms: ICI 211965; ICI-211965; ICI211965; 1-(3-(Naphth-2-ylmethoxy)phenyl)-1-(thiazol-2-yl)propyl methyl ether. Grade: 98%. CAS No. 129424-08-4. Molecular formula: C24H23NO2S. Mole weight: 389.52.
ICI 216140
ICI 216140 is a GRP/bombesin receptor 2 antagonist (IC50 = 2 nM in vitro). Grade: ≥95%. CAS No. 124001-41-8. Molecular formula: C45H65N13O8. Mole weight: 916.1.
ICI 63197
ICI 63197 is a specific and potent cAMP phosphodiesterase IV (PDE 4) inhibitor. Its IC50 value is 35 nM for inhibition of [3H]-rolipram binding to rat brain. It is potent in anatagonizing reserpine-induced hypothermia. It has an antidepressant effect following systemic administration in vivo. Synonyms: ICI 63197; ICI63197; ICI-63197; 2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5(4H)-one; 2-Amino-4,5-dihydro-6-methyl-4-propyl-s-triazolo[1,5-a]pyrimidin-5-one. Grade: ≥99% by HPLC. CAS No. 27277-00-5. Molecular formula: C9H13N5O. Mole weight: 207.23.
ICI 89406
ICI 89406 is a selective β-adrenergic antagonist. It is a low efficacy partial agonist and does not affect resting cardiac parameters. Synonyms: ICI 89406; ICI89406; ICI-89406; N-[2-[3-(2-Cyanophenoxy)-2-hydroxypropylamino]ethyl]-N'-phenylurea. Grade: ≥99% by HPLC. CAS No. 53671-71-9. Molecular formula: C19H22N4O3. Mole weight: 354.41.
Icilin
Icilin is a synthetic CMR1/TRPM8 super agonist in CMR1-expressing HEK 293 cells (EC50 = 0.36 μM) more potently than menthol or low temperatures. Uses: Both heat sensitive (vr1) and cold-sensitive (cmr1 (rat); trpm8 (human)) receptors. Synonyms: AG 3-5; AG3-5; AG-3-5; AG 3-5 cpd; 3,4-Dihydro-3-(2-hydroxyphenyl)-6-(3-nitrophenyl)-(1H)-pyrimidin-2-one; 3,6-dihydro-1-(2-hydroxyphenyl)-4-(3-nitrophenyl)-2(1H)-pyrimidinone. Grade: ≥98%. CAS No. 36945-98-9. Molecular formula: C16H13N3O4. Mole weight: 311.29.
Iclaprim
Iclaprim is a diaminopyrimidine and acts as a dihydrofolate reductase (DHFR) inhibitor active against gram-positive organisms being developed for the treatment of complicated skin and soft tissue infections caused by antibiotic-resistant bacteria. Synonyms: AR-100; 5-[(2-cyclopropyl-7,8-dimethoxy-2h-chromen-5-yl)methyl]pyrimidine-2,4-diamine; RO-48-2622. CAS No. 192314-93-5. Molecular formula: C19H22N4O3. Mole weight: 354.41.
ICL-CCIC-0019
ICL-CCIC-0019 is a choline kinase alpha (CHKA) inhibitor. Synonyms: ICL CCIC 0019; ICLCCIC0019. CAS No. 936498-64-5. Molecular formula: C26H44Br2N4. Mole weight: 572.47.
Iclepertin
Iclepertin, a glycine transporter inhibitor, is an antipsychotic drug. Synonyms: [5-(methanesulfonyl)-2-{[(2R)-1,1,1-trifluoropropan-2-yl]oxy}phenyl]{(1R,5R)-1-[5-(trifluoromethyl)-1,2-oxazol-3-yl]-3-azabicyclo[3.1.0]hexan-3-yl}methanone; (5-(methylsulfonyl)-2-(((R)-1,1,1-trifluoropropan-2-yl)oxy)phenyl)((1R,5R)-1-(5-(trifluoromethyl)isoxazol-3-yl)-3-azabicyclo[3.1.0]hexan-3-yl)methanone. CAS No. 1421936-85-7. Molecular formula: C20H18F6N2O5S. Mole weight: 512.42.
ICMT-IN-1
ICMT-IN-1 is an inhibitor of ICMT (IC50=0.0013 μM). CAS No. 1313603-22-3. Molecular formula: C24H33NO2. Mole weight: 367.52.
ICMT-IN-10
ICMT-IN-10 is an inhibitor of ICMT (IC50=0.184 μM). CAS No. 1313602-78-6. Molecular formula: C22H26F3NO2. Mole weight: 393.44.
ICMT-IN-11
ICMT-IN-11 is an inhibitor of ICMT (IC50=0.031 μM). CAS No. 1313602-94-6. Molecular formula: C22H27F2NO2. Mole weight: 375.45.
ICMT-IN-12
ICMT-IN-12 is an inhibitor of ICMT (IC50=0.42 μM). CAS No. 1313603-25-6. Molecular formula: C24H33NOS. Mole weight: 383.59.
ICMT-IN-13
ICMT-IN-13 is an inhibitor of ICMT (IC50=0.47 μM). CAS No. 1313602-95-7. Molecular formula: C21H25ClFNO. Mole weight: 361.88.
ICMT-IN-14
ICMT-IN-14 is an inhibitor of ICMT (IC50=0.025 μM). CAS No. 1313602-97-9. Molecular formula: C21H25ClFNO. Mole weight: 361.88.
ICMT-IN-15
ICMT-IN-15 is an inhibitor of ICMT (IC50=0.032 μM). CAS No. 1313602-98-0. Molecular formula: C21H25ClFNO. Mole weight: 361.88.
ICMT-IN-16
ICMT-IN-16 is an inhibitor of ICMT (IC50=0.131 μM). CAS No. 1313602-79-7. Molecular formula: C23H32N2O. Mole weight: 352.51.
ICMT-IN-17
ICMT-IN-17 is an inhibitor of ICMT (IC50=0.38 μM). CAS No. 1313602-99-1. Molecular formula: C22H26F3NO. Mole weight: 377.44.
ICMT-IN-18
ICMT-IN-18 is an inhibitor of ICMT (IC50=0.066 μM). CAS No. 1313602-81-1. Molecular formula: C22H26N2O. Mole weight: 334.45.
ICMT-IN-19
ICMT-IN-19 is an inhibitor of ICMT (IC50=0.026 μM). CAS No. 1313603-00-7. Molecular formula: C21H26N2O3. Mole weight: 354.44.
ICMT-IN-2
ICMT-IN-2 is an inhibitor of ICMT (IC50=0.168 μM). CAS No. 1313602-91-3. Molecular formula: C21H26FNO. Mole weight: 327.44.
ICMT-IN-20
ICMT-IN-20 is an inhibitor of ICMT (IC50=0.682 μM). CAS No. 1313603-01-8. Molecular formula: C21H26N2O3. Mole weight: 354.44.
ICMT-IN-21
ICMT-IN-21, a sulfonamide-modified farnesyl cysteine (SMFC), is an ICMT inhibitor (IC50=8.8 μM). Synonyms: 2-thienyl-sulfonamido-farnesylcysteine. CAS No. 1310740-69-2. Molecular formula: C22H33NO4S3. Mole weight: 471.70.
ICMT-IN-22
ICMT-IN-22 is an inhibitor of ICMT (IC50=0.63 μM). CAS No. 1313603-09-6. Molecular formula: C22H28ClNO2. Mole weight: 373.92.
ICMT-IN-23
ICMT-IN-23 is an inhibitor of ICMT (IC50=0.123 μM). CAS No. 1313602-82-2. Molecular formula: C22H26N2O. Mole weight: 334.45.
ICMT-IN-24
ICMT-IN-24 is an inhibitor of ICMT (IC50=0.19 μM). CAS No. 1313603-10-9. Molecular formula: C22H28ClNO2. Mole weight: 373.92.
ICMT-IN-25
ICMT-IN-25 is an inhibitor of ICMT (IC50=0.025 μM). CAS No. 1313602-83-3. Molecular formula: C21H26ClNO. Mole weight: 343.89.
ICMT-IN-26
ICMT-IN-26 is an inhibitor of ICMT (IC50=0.36 μM). CAS No. 1313602-84-4. Molecular formula: C21H26ClNO. Mole weight: 343.89.
ICMT-IN-27
ICMT-IN-27 is an inhibitor of ICMT (IC50=0.1 μM). CAS No. 1313603-11-0. Molecular formula: C22H28FNO2. Mole weight: 357.46.
ICMT-IN-28
ICMT-IN-28 is an inhibitor of ICMT (IC50=0.008 μM). CAS No. 1313603-12-1. Molecular formula: C22H28FNO2. Mole weight: 357.46.
ICMT-IN-29
ICMT-IN-29 is an inhibitor of ICMT (IC50=0.019 μM). CAS No. 1313603-13-2. Molecular formula: C20H27NO2S. Mole weight: 345.50.
ICMT-IN-3
ICMT-IN-3 is an inhibitor of ICMT (IC50=0.015 μM). CAS No. 1313602-73-1. Molecular formula: C22H29NO2. Mole weight: 339.47.
ICMT-IN-30
ICMT-IN-30 is an inhibitor of ICMT (IC50=0.27 μM). CAS No. 1313603-14-3. Molecular formula: C19H25NOS. Mole weight: 315.47.
ICMT-IN-31
ICMT-IN-31 is an inhibitor of ICMT (IC50=0.0038 μM). CAS No. 1313603-15-4. Molecular formula: C19H24ClNOS. Mole weight: 349.92.
ICMT-IN-32
ICMT-IN-32 is an inhibitor of ICMT (IC50=0.777 μM). CAS No. 1313603-17-6. Molecular formula: C20H25NO2. Mole weight: 311.42.
ICMT-IN-33
ICMT-IN-33 is an inhibitor of ICMT (IC50=0.46 μM). CAS No. 1313603-20-1. Molecular formula: C20H24ClNO. Mole weight: 329.86.
ICMT-IN-34
ICMT-IN-34 is an inhibitor of ICMT (IC50=0.17 μM). CAS No. 1313602-85-5. Molecular formula: C21H25Cl2NO. Mole weight: 378.34.
ICMT-IN-35
ICMT-IN-35, a FTPA-triazole compound, is an ICMT inhibitor (IC50=0.8 μM). Molecular formula: C25H29N3O2S. Mole weight: 435.58.
ICMT-IN-36
ICMT-IN-36 is an inhibitor of ICMT (IC50=0.181 μM). CAS No. 1313602-86-6. Molecular formula: C21H25Cl2NO. Mole weight: 378.34.
ICMT-IN-37
ICMT-IN-37 is an inhibitor of ICMT (IC50=0.308 μM). CAS No. 1313602-87-7. Molecular formula: C22H28ClNO. Mole weight: 357.92.
ICMT-IN-38
ICMT-IN-38 is an inhibitor of ICMT (IC50=0.049 μM). CAS No. 1313602-88-8. Molecular formula: C22H28ClNO. Mole weight: 357.92.
ICMT-IN-39
ICMT-IN-39 is an inhibitor of ICMT (IC50=0.031 μM). CAS No. 1313602-64-0. Molecular formula: C22H29NO. Mole weight: 323.47.
ICMT-IN-4
ICMT-IN-4 is an inhibitor of ICMT (IC50=0.27 μM). CAS No. 1313602-74-2. Molecular formula: C22H29NO2. Mole weight: 339.47.
ICMT-IN-40
ICMT-IN-40 is an inhibitor of ICMT (IC50=0.031 μM). CAS No. 1313602-65-1. Molecular formula: C22H29NO. Mole weight: 323.47.
ICMT-IN-41
ICMT-IN-41 is an inhibitor of ICMT (IC50=0.069 μM). CAS No. 1313602-66-2. Molecular formula: C23H31NO. Mole weight: 337.50.
ICMT-IN-42
ICMT-IN-42 is an inhibitor of ICMT (IC50=0.054 μM). CAS No. 1313602-67-3. Molecular formula: C23H31NO. Mole weight: 337.50.
ICMT-IN-43
ICMT-IN-43 is an inhibitor of ICMT (IC50=0.04 μM). CAS No. 1313602-68-4. Molecular formula: C23H31NO. Mole weight: 337.50.
ICMT-IN-44
ICMT-IN-44 is an inhibitor of ICMT (IC50=0.167 μM). CAS No. 1313602-69-5. Molecular formula: C24H33NO. Mole weight: 351.52.