BOC Sciences 8 - Products
BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
Product | Description | |
---|---|---|
SGC GAK 1 Quick inquiry Where to buy | SGC GAK 1 is a high affinity cyclin G associated kinase (GAK) inhibitor with >30-fold selectivity for GAK over a panel of other kinases. Synonyms: SGC-GAK-1; BCP30478; 6-Bromo-N-(3,4,5-trimethoxyphenyl)-4-quinolinamine. Grades: ≥99% by HPLC. CAS No. 2226517-76-4. Molecular formula: C18H17BrN2O3. Mole weight: 389.24. | |
SHP099 Quick inquiry Where to buy | SHP099 is a potent, selective, orally bioavailable, and efficacious SHP2 inhibitor (IC50 value 0.071 μM) that stabilizes SHP2 in an auto-inhibited conformation. SHP099 suppresses signaling through the Ras-ERK pathway and blocks the proliferation of receptor tyrosine kinase-driven human cancer cells in vitro and in vivo. Synonyms: 6-(4-amino-4-methylpiperidin-1-yl)-3-(2,3-dichlorophenyl)pyrazin-2-amine; SHP099; SHP-099; SHP 099. CAS No. 1801747-42-1. Molecular formula: C16H19Cl2N5. Mole weight: 352.26. | |
SHP099 HCl Quick inquiry Where to buy | SHP099 is a potent, selective, orally bioavailable, and efficacious SHP2 inhibitor (IC50 value 0.071 μM) that stabilizes SHP2 in an auto-inhibited conformation. SHP099 suppresses signaling through the Ras-ERK pathway and blocks the proliferation of receptor tyrosine kinase-driven human cancer cells in vitro and in vivo. Synonyms: 6-(4-amino-4-methylpiperidin-1-yl)-3-(2,3-dichlorophenyl)pyrazin-2-amine hydrochloride; SHP099; SHP-099; SHP 099. SHP-099 hydrochloride, SHP-099 HCl. CAS No. 1801747-11-4. Molecular formula: C16H20Cl3N5. Mole weight: 388.72. | |
Silodosin Dehydro Impurity Quick inquiry Where to buy | An impurity of Silodosin. Silodosin is an α1-adrenoceptor antagonist for the treatment of benign prostatic hypertrophy. Synonyms: 1- (3-Hydroxypropyl) -5-[ (2R) -2-[[2-[2- (2, 2, 2-trifluoroethoxy) phenoxy]ethyl]amino]propyl]-1H-indole-7-carboxamide; Dehydro Silodosin. Grades: > 95%. CAS No. 175870-21-0. Molecular formula: C25H30F3N3O4. Mole weight: 493.53. | |
Silodosin S-Isomer Quick inquiry Where to buy | An isomer of Silodosin, which is used in the treatment of the symptoms of an enlarged prostate (benign prostatic hyperplasia; BPH) in men. Synonyms: Silodosin (S)-Isomer; (S)-Silodosin; 1- (3-Hydroxypropyl) -5-[ (2S) - ({2-[2-[2- (2, 2, 2-trifluoroethoxy) phenoxy]ethyl}amino) propyl]indoline-7-carboxamide; (S) -1- (3-Hydroxypropyl) -5- (2- ( (2- (2- (2, 2, 2-trifluoroethoxy) phenoxy) ethyl) amino) propyl) indoline-7-carboxamide. CAS No. 2182279-45-2. Molecular formula: C25H32F3N3O4. Mole weight: 495.53. | |
Simeprevir Quick inquiry Where to buy | Simeprevir plays an important role in HCV replication. Data from phase I and II clinical trials of TMC-435350 (TMC 435350; TMC 435; TMC-435350) to date have shown that this agent is well tolerated as a once-daily oral therapy and provides potent antiviral activity in HCV genotype 1-infected subjects, with restoration of liver enzymes and no evidence of viral breakthrough. Synonyms: TMC435; TMC 435; TMC-435; TMC435350; TMC-435350; TMC 435350. Grades: 98%. CAS No. 923604-59-5. Molecular formula: C38H47N5O7S2. Mole weight: 749.942. | |
Simvastatin EP Impurity N Quick inquiry Where to buy | An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: Methylsimvastatin; 5-Methylsimvastatin; 2-Methyl Simvastatin (Mixture Of Diasteroisomers); 2,2-Dimethyl-(1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-5-methyl-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester Butanoic Acid. CAS No. 774611-54-0. Molecular formula: C26H40O5. Mole weight: 432.59. | |
Sinapultide Quick inquiry Where to buy | Sinapultide is a synthetic protein that mimics human lung surfactant protein B. This compound is undergoing preclinical development in lung disorders, and is planned for a phase III clinical trial for aerosol delivery system (ADS) in Respiratory distress syndrome. Synonyms: KL4 peptide. Grades: >95%. CAS No. 138531-07-4. Molecular formula: C126H238N26O22. Mole weight: 2469.45. | |
(S)-Indacaterol Quick inquiry Where to buy | An isomerous impurity of Indacaterol. Indacaterol is an ultra-long-acting β-adrenoceptor agonist used as an oral inhaled bronchodilator. It is indicated for the treatment of patients with chronic obstructive pulmonary disease (COPD). Synonyms: 5-[(1S)-2-[(5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-hydroxy-2(1H)-quinolinone. Grades: 95%. CAS No. 1235445-80-3. Molecular formula: C24H28N2O3. Mole weight: 392.499. | |
Siponimod Quick inquiry Where to buy | Siponimod is a selective S1P1 and S1P5 agonist with EC50 of 0.39 nM and 0.98 nM, respectively. It has been approved by US FDA for the treatment of patients with active secondary progressive multiple sclerosis (SPMS). Synonyms: BAF-312; BAF 312; BAF312; Siponimod; Mayzent; 1-[[4-[(E)-N-[[4-cyclohexyl-3-(trifluoromethyl)phenyl]methoxy]-C-methylcarbonimidoyl]-2-ethylphenyl]methyl]azetidine-3-carboxylic acid. Grades: >98%. CAS No. 1230487-00-9. Molecular formula: C29H35F3N2O3. Mole weight: 516.6. | |
Sisunatovir Quick inquiry Where to buy | Sisunatovir is a highly potent fusion inhibitor with efficacy against a panel of clinical isolates of RSV-A and RSV-B viruses. Sisunatovir exhibited a mean IC50 of 1.2 nM against a panel of RSV A and B laboratory strains and clinical isolates with antiviral efficacy in the Balb/C mouse model of RSV infection. Synonyms: RV-521; RV 521; RV521. Grades: 99.08%. CAS No. 1903763-82-5. Molecular formula: C23H22F4N4O. Mole weight: 446.44. | |
SKF-86002 Quick inquiry Where to buy | SKF-86002 is a p38 MAP kinase inhibitor, the IC50 is 0.1 - 1 μM. It potently inhibits LPS-induced IL-1 and TNF-α production in human monocytes, the IC50 is1 μM. It also acts as an inhibitor of both cyclooxygenase (COX) and 5-lipoxygenase (5-LO). In vitro: SKF-86002 inhibited prostaglandin H2 synthase activity, the IC50 is 120 mM as well as prostanoid production by rat basophilic leukemia cells, the IC50 is mM and its sonicate ( the IC50 is 100 mM and human monocytes (the IC50 is 1 mM. It inhibited the generation of dihydroxyeicosatetraenoic acid and 5-hydroxyeicosatetraenoic acid by a high speed supernatant fraction of RBL-1 cells (the IC50 is 10 mM). It blocked superoxide anion production in response to FMLP and reduced adhesion and chemotaxis in response to PAF or FMLP. Uses: Skf-86002 could potently inhibit lps-induced il-1 and tnf-α production in human monocytes. it acts as an inhibitor of both cyclooxygenase and 5-lipoxygenase. Synonyms: SKF-86002; SKF 86002; SKF86002. 6-(4-fluorophenyl)-5-(4-pyridyl)-2,3-dihydroimidazo[2,1-b]-thiazole; 4-(4-Pyridyl)-5-(4-fluorophenyl)-2,3-dihydro-1-thia-3a,6-diazapentalene. Grades: >98%. CAS No. 72873-74-6. Molecular formula: C16H12FN3S. Mole weight: 297.36. | |
SKQ1 Quick inquiry Where to buy | SKQ1, also known as plastoquinonyl decyltriphenyl phosphonium or PDTP, is a potent mitochondria-targeted antioxidant. SKQ1 is also an API (active pharmaceutical ingredient) for making eye drop drug called Visomitin. Synonyms: SKQ1; SKQ 1; SKQ-1; PDTP; Plastoquinonyl decyltriphenyl phosphonium bromide; Visomitin. Grades: 95%. CAS No. 934826-68-3. Molecular formula: C36H42BrO2P. Mole weight: 617.61. | |
Slv319 Quick inquiry Where to buy | Slv319 is a potent antagonist of CB1 recceptor (Ki = 7.8 nM) used for the treatment of neuroinflammatory disorders, cognitive disorders, septic shock, obesity, psychosis, addiction and gastrointestinal disorders, as well as inhibits CP 55,940-induced hypotension and WIN 55,212-2-induced hypothermia in vivo. Synonyms: Slv319; Slv 319; Slv-319; 3-(4-Chlorophenyl)-N-[(4-chlorophenyl)sulfonyl]-4,5-dihydro-N'-methyl-4-phenyl-1H-pyrazole-1-carboximidamide; CHEMBL158784. Grades: 98%. CAS No. 362519-49-1. Molecular formula: C23H20Cl2N4O2S. Mole weight: 487.399. | |
SM-164 Quick inquiry Where to buy | SM-164 is a potent cell-permeable and bivalent Smac mimetic which bind to a XIAP protein and binds to cIAP-1 and cIAP-2 proteins. It is developed as an anticancer agent. It plays its antitumor roles through inducing degradation of cellular inhibitor of apoptosis protein (cIAP)-1/2, antagonizing X-linked inhibitor of apoptosis protein (XIAP) and inducing TNFα-dependent apoptosis in tumor cells. It binds to cIAP-1 protein containing bothBIR2 and BIR3 domains, cIAP-2 BIR3 protein and XIAP protein containing both BIR2 and BIR3 domains. Synonyms: SM 164; SM164; SM-164. Grades: >98%. CAS No. 957135-43-2. Molecular formula: C62H84N14O6. Mole weight: 1121.42. | |
Smad3 Inhibitor, SIS3 Quick inquiry Where to buy | Smad3 Inhibitor, SIS 3 is an inhibitor of SMAD3, which is a receptor-regulated intracellular protein that functions downstream of TGF-β as well as activin receptors and mediates their signaling. It plays an important role in cell proliferation, apoptosis, differentiation and formation of extracellular matrix. It is a cell-permeable pyrrolopyridine compound that selectively inhibits TGF-β1-dependent Smad3 phosphorylation and Smad3-mediated cellular signaling. It has been shown to reduce TGF-β1-induced type 1 procollagen expression and myofibroblast differentiation in normal dermal fibroblasts as well as scleroderma fibroblasts. Synonyms: 1-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-3-(1-methyl-2-phenylpyrrolo[2,3-b]pyridin-3-yl)prop-2-en-1-one. CAS No. 1009104-85-1. Molecular formula: C28H27N3O3. Mole weight: 453.542. | |
(S)-Methyl 1- ( (S) -2- ( ( (S) -1- (Benzyloxy) -1-oxo-4-phenylbutan-2-yl) amino) -6- ( ( (benzyloxy) carbonyl) amino) hexanoyl) pyrrolidine-2-carboxylate Quick inquiry Where to buy | (S)-Methyl 1- ( (S) -2- ( ( (S) -1- (Benzyloxy) -1-oxo-4-phenylbutan-2-yl) amino) -6- ( ( (benzyloxy) carbonyl) amino) hexanoyl) pyrrolidine-2-carboxylate is an intermediate in the synthesis of Lisinopril, which is an angiotensin-converting enzyme inhibitor used in the treatment of hypertension, congestive heart failure, and heart attacks. Synonyms: Methyl N6-[(benzyloxy)carbonyl]-N2-[(2S)-1-(benzyloxy)-1-oxo-4-phenyl-2-butanyl]-L-lysyl-L-prolinate; L-Proline, N6-[(phenylmethoxy)carbonyl]-N2-[(1S)-3-phenyl-1-[(phenylmethoxy)carbonyl]propyl]-L-lysyl-, methyl ester. Molecular formula: C37H45N3O7. Mole weight: 643.77. | |
(S)-methyl 2-(2,3-bis(hydroxymethyl)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)-2-(2-chlorophenyl)acetate Quick inquiry Where to buy | (S)-methyl 2-(2,3-bis(hydroxymethyl)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)-2-(2-chlorophenyl)acetate is an impurity of Clopidogrel, an antithrombotic agent. Synonyms: Thieno[3,2-c]pyridine-5(4H)-acetic acid, α-(2-chlorophenyl)-6,7-dihydro-2,3-bis(hydroxymethyl)-, methyl ester, (αS)-; Clopidogrel Impurity 30. Grades: 95%. CAS No. 1346231-36-4. Molecular formula: C18H20ClNO4S. Mole weight: 381.87. | |
(S)-methyl 2-(2-chlorophenyl)-2-(2-(hydroxymethyl)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate Quick inquiry Where to buy | (S)-methyl 2-(2-chlorophenyl)-2-(2-(hydroxymethyl)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate is an impurity of Clopidogrel, an antithrombotic agent. Synonyms: Clopidogrel Bisulfate Impurity 29. CAS No. 1346231-35-3. Molecular formula: C17H18ClNO3S. Mole weight: 351.85. | |
S-Methyl-L-Cysteine-S-oxide Quick inquiry Where to buy | S-Methyl-L-Cysteine-S-oxide is an alliin analogue. Synonyms: 2-Amino-3-methylsulfinylpropanoic acid. Grades: > 95%. CAS No. 6853-87-8. Molecular formula: C4H9NO3S. Mole weight: 151.19. | |
S-Methyl N, N-Diethyldithiocarbamate Quick inquiry Where to buy | S-Methyl N,N-diethyldithiocarbamate (MeDDC) is a metabolite of the alcohol deterrent disulfiram. Uses: Enzyme inhibitors. Synonyms: N,N-Diethylcarbamodithioic Acid Methyl Ester; Diethyldithiocarbamic Acid Methyl Ester. Grades: > 95%. CAS No. 686-07-7. Molecular formula: C6H13NS2. Mole weight: 163.31. | |
S-Methyl Tiopronin Quick inquiry Where to buy | S-Methyl Tiopronin is a metabolite of Tiopronin, which is used as an antidote against heavy metal poisoning. Uses: A metabolite of tiopronin. Synonyms: S-Methylthiola; S-Methylmercaptopropionylglycine; N-[2-(Methylthio)-1-oxopropyl]glycine; Rac-S-Methyl Tiopronin; N-[2-(Methylsulfanyl)propanoyl]glycine; Tiopronin S-Methyl Impurity; Glycine, N-[2-(methylthio)-1-oxopropyl]-. Grades: 95%. CAS No. 87254-91-9. Molecular formula: C6H11NO3S. Mole weight: 177.22. | |
(S)-Montelukast Quick inquiry Where to buy | Cas No. 220927-27-5. | |
(S)-N-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)acetamide Quick inquiry Where to buy | (S)-N-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)acetamide is an impurity of Apremilast, which is an oral phosphodiesterase 4 inhibitor used for treating psoriatic arthritis. Synonyms: (S)-N-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)acetamide; SCHEMBL15198848; 2097600-16-1. CAS No. 2097600-16-1. Molecular formula: C14H21NO5S. Mole weight: 315.38. | |
(S)-N-(2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-5-yl)acetamide Quick inquiry Where to buy | (S)-N-(2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-5-yl)acetamide is an impurity of Apremilast, which is an oral phosphodiesterase 4 inhibitor used for treating psoriatic arthritis. CAS No. 2201974-01-6. Molecular formula: C22H24N2O7S. Mole weight: 460.50. | |
(S)-N-((3-(3-fluoro-4-(2H-1,4-oxazin-4(3H)-yl)phenyl)-2-oxooxazolidin-5-yl)methyl)acetamide Quick inquiry Where to buy | (S)-N-((3-(3-fluoro-4-(2H-1,4-oxazin-4(3H)-yl)phenyl)-2-oxooxazolidin-5-yl)methyl)acetamide is an impurity of Linezolid, an oxazolidinone antimicrobial that is used to treat infections against gram-positive bacteria, especially those that are drug-resistant. Linezolid works by inhibiting bacterial protein synthesis. Synonyms: Acetamide, N-[[(5S)-3-[4-(2,3-dihydro-4H-1,4-oxazin-4-yl)-3-fluorophenyl]-2-oxo-5-oxazolidinyl]methyl]-; Linezolid Impurity 39. CAS No. 1997296-64-6. Molecular formula: C16H18FN3O4. Mole weight: 335.33. | |
(S)-N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)propionamide Quick inquiry Where to buy | (S)-N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)propionamide is an impurity of Linezolid, an oxazolidinone antimicrobial that is used to treat infections against gram-positive bacteria, especially those that are drug-resistant. Linezolid works by inhibiting bacterial protein synthesis. Synonyms: Linezolid Impurity 08. CAS No. 216869-17-9. Molecular formula: C17H22FN3O4. Mole weight: 351.37. | |
(S)-N4-(4-Fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine Quick inquiry Where to buy | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: 4,6-Quinazolinediamine, N4-(4-fluorophenyl)-7-[[(3S)-tetrahydro-3-furanyl]oxy]; Afatinib Impurity P. Grades: ≥95%. CAS No. 2413212-07-2. Molecular formula: C18H17FN4O2. Mole weight: 340.35. | |
(S)-N-Desmethyl Duloxetine Hydrochloride Quick inquiry Where to buy | (S)-N-Desmethyl Duloxetine Hydrochloride is an impurity of Duloxetine, which is a serotonin-norepinephrine reuptake inhibitor used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, neuropathic pain and central sensitization. Synonyms: (γS)-γ-(1-Naphthalenyloxy)-2-thiophenepropanamine Hydrochloride; (S)-γ-(1-Naphthalenyloxy)-2-thiophenepropanamine Hydrochloride; (3S)-3-(1-Naphthyloxy)-3-(2-thienyl)-1-propanamine hydrochloride (1:1); 2-Thiophenepropanamine, γ-(1-naphthalenyloxy)-, (γS)-, hydrochloride (1:1). CAS No. 1798887-69-0. Molecular formula: C17H18ClNOS. Mole weight: 319.85. | |
(S)-N-Didemethyl Dapoxetine Quick inquiry Where to buy | (S)-N-Didemethyl Dapoxetine is an impurity of Dapoxetine. Dapoxetine HCl is a novel short-acting selective serotonin reuptake inhibitor. Uses: The (s)-metabolite of dapoxetine (d185700). selective serotonin reuptake inhibitor antidepressant. Synonyms: (S) -α -[2- (1-Naphthalenyloxy) ethyl]benzenemethanamine. CAS No. 147199-40-4. Molecular formula: C19H19NO. Mole weight: 277.36. | |
(S)-(+)-Nirvanol Quick inquiry Where to buy | (S)-(+)-Nirvanol is a Mephentoin metabolite with anticonvulsant and hypnotic properties. Uses: An anticonvulsant, hypnotic. a metabolite of mephentoin. Synonyms: (+)-5-Ethyl-5-phenylhydantoin; S-Nirvanol. CAS No. 65567-34-2. Molecular formula: C11H12N2O2. Mole weight: 204.23. | |
S-(N-Methylcarbamoyl)-L-cysteine Quick inquiry Where to buy | . Uses: A metabolite of n-methylformamide. Synonyms: S-[(Methylamino)carbonyl]-L-cysteine; L-Cysteine Methylcarbamate (Ester). Grades: ≥95%. CAS No. 7324-17-6. Molecular formula: C5H10N2O3S. Mole weight: 178.21. | |
(S)-N,N-dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-3-yl)propan-1-amine Quick inquiry Where to buy | (S)-N,N-dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-3-yl)propan-1-amine is an impurity of Duloxetine, an antidepressant medication used to treat major depressive disorder. Synonyms: Duloxetine IMpurity 19. CAS No. 1384080-33-4. Molecular formula: C8H13NOS. Mole weight: 171.26. | |
sobutyl 2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate Quick inquiry Where to buy | An impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Synonyms: iso-butyl ester of febuxostat; 5-Thiazolecarboxylic acid, 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-, 2-methylpropyl ester; Febuxostat Impurity 67. CAS No. 923942-36-3. Molecular formula: C20H24N2O3S. Mole weight: 372.48. | |
Sodium 2-Methyl-4,5-Dihydro-1,3-Thiazol-4-Carboxylate Quick inquiry Where to buy | Sodium 2-Methyl-4,5-Dihydro-1,3-Thiazol-4-Carboxylate is an impurity of Acetylcysteine. Synonyms: 2-methyl-4,5-dihydro-1,3-thiazole-4-carboxylate; 2-Methyl-2-thiazoline-4-carboxylic acid sodium salt; Acetylcysteine Impurity 1 Sodium Salt. Grades: > 95%. CAS No. 15058-19-2. Molecular formula: C5H6NO2SNa. Mole weight: 167.16. | |
sodium 7-((3-iodo-6-methyl-5,5-dioxido-6,11-dihydrodibenzo[c,f][1,2]thiazepin-11-yl)amino)heptanoate Quick inquiry Where to buy | An impurity of Tianeptine, which is a selective serotonin reuptake enhancer (SSRE) used for treating major depressive episodes. CAS No. 1809278-35-0. Molecular formula: C21H24IN2NaO4S. Mole weight: 550.39. | |
Sodium diethyldithiocarbamate Quick inquiry Where to buy | Diethyldithiocarbamate is a chelating agent that has been used to mobilize toxic metals from the tissues of humans and experimental animals. Uses: Adjuvants, immunologic. Synonyms: Diethyldithiocarbamic acid sodium salt. Grades: > 95%. CAS No. 20624-25-3. Molecular formula: (C2H5)2NCSSNa·3H2O. Mole weight: 225.31. | |
Sodium glycochenodeoxycholate Quick inquiry Where to buy | Sodium glycochenodeoxycholate is a bile salt formed in the liver from chenodeoxycholate and glycine, usually as the sodium salt. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is a cholagogue and choleretic. Synonyms: Glycochenodeoxycholic acid sodium salt. CAS No. 16564-43-5. Molecular formula: C26H42NNaO5. Mole weight: 471.614. | |
Sodium glycocholate hydrate Quick inquiry Where to buy | Cholylglycine is a crystalline bile acid involved in the emulsification of fats. Sodium glycocholate hydrate is used to assess serum total bile acids via a fluorimetric and enzymatic method. Synonyms: Glycocholic acid sodium salt hydrate; N-Cholylglycine sodium salt; N-[(3α, 5β, 7α, 12α)-3, 7, 12-Trihydroxy-24-oxocholan-24-yl]-glycine Sodium Salt Hydrate. Grades: ≥98%. CAS No. 338950-81-5. Molecular formula: C26H42NO6Na·xH2O. Mole weight: 487.60 (anhydrous basis). | |
sodium (R,Z)-2-((1S,2R)-1-carboxylato-2-hydroxypropyl)-5-(4-hydroxybutylidene)-2,5-dihydrothiazole-4-carboxylate Quick inquiry Where to buy | sodium (R,Z)-2-((1S,2R)-1-carboxylato-2-hydroxypropyl)-5-(4-hydroxybutylidene)-2,5-dihydrothiazole-4-carboxylate is an impurity of faropenem, an orally active beta-lactam antibiotic belonging to the penem group. Synonyms: Disodium (2R,5Z)-2-(carboxylatomethyl)-5-(4-hydroxybutylidene)-2-[(1R)-1-hydroxyethyl]-2,5-dihydro-1,3-thiazole-4-carboxylate. CAS No. 130609-10-8. Molecular formula: C12H15NNa2O6S. Mole weight: 347.30. | |
Sodium taurodeoxycholate hydrate Quick inquiry Where to buy | Sodium taurodeoxycholate hydrate is a bile salt-related, anionic detergent used for isolation of membrane proteins. Synonyms: Taurodeoxycholic acid sodium salt hydrate; Taurodeoxycholic acid sodium salt monohydrate. CAS No. 207737-97-1. Molecular formula: C26H46NNaO7S. Mole weight: 539.704. | |
Sofosbuvir Quick inquiry Where to buy | Sofosbuvir is a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled sofosbuvir as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase. Uses: Antiviral agents. Synonyms: PSI-7977; PSI 7977; PSI7977; GS7977; GS-7977; GS 7977; Sovaldi; N-[[P(S),2'R]-2'-deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-L-alanine, 1-methylethyl ester; Hepcinat; Hepcvir; Resof; SoviHep. Grades: >98%. CAS No. 1190307-88-0. Molecular formula: C22H29FN3O9P. Mole weight: 529.45. | |
Sofosbuvir Impurity 34 (GS-606965) Quick inquiry Where to buy | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: 5'-Uridylic acid, 2'-deoxy-2'-fluoro-2'-methyl-, (2'R)?-; (2'R)-2'-Deoxy-2'-fluoro-2'-methyl-5'-uridylic acid; PSI 7411. Grades: > 95%. CAS No. 1015073-43-4. Molecular formula: C10H14FN2O8P. Mole weight: 340.2. | |
Sofosbuvir Impurity 35 Quick inquiry Where to buy | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: (2'R)-2'-Chloro-2'-deoxy-2'-methyl-uridine; Chloro Sofosbuvir Desphosphate. Grades: > 95%. CAS No. 1496551-72-4. Molecular formula: C10H13ClN2O5. Mole weight: 276.68. | |
Sofosbuvir impurity C Quick inquiry Where to buy | An impurity of Sofosbuvir, a medication used to treat hepatitis C. Synonyms: Sofosbuvir impurity A; (2R)-isopropyl 2- ( ( ( ( (2R, 3R, 4R, 5R)-5- (2, 4-dioxo-3, 4-dihydropyrimidin-1 (2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy) (phenoxy)phosphoryl)amino)propanoate. CAS No. 1496552-28-3. Molecular formula: C22H29FN3O9P. Mole weight: 529.5. | |
Sofosbuvir Impurity (GS-566500) Quick inquiry Where to buy | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: L-Alanine, N-[(2'R)?-2'-deoxy-2'-fluoro-2'-methyl-5'-uridylyl]?-; N-[(2'R)-2'-Deoxy-2'-fluoro-2'-methyl-5'-uridylyl]-L-alanine; PSI 352707. Grades: > 95%. CAS No. 1233335-78-8. Molecular formula: C13H19FN3O9P. Mole weight: 411.28. | |
Sograzepide Quick inquiry Where to buy | Sograzepide, a benzodiazepin derivative, has been found to be a gastric receptor as well as CCK2 receptor antagonist that could be useful against chronic atrophic gastritis and gastric carcinoid at some extent. Synonyms: YF476; YF-476; YF 476; Netazepide; Sograzepide; UNII-HOU4I0G29C; YF 476; CHEMBL324547; 1-[(3R)-1-(3,3-dimethyl-2-oxobutyl)-2-oxo-5-pyridin-2-yl-3H-1,4-benzodiazepin-3-yl]-3-[3-(methylamino)phenyl]urea. Grades: ≥ 95% (HPLC). CAS No. 155488-25-8. Molecular formula: C28H30N6O3. Mole weight: 498.58. | |
Solifenacin EP Impurity C Quick inquiry Where to buy | An impurity of Solifenacin. Solifenacin is a muscarinic M3 receptor antagoinst for treating contraction of overactive bladder with associated problems such as increased urination frequency and urge incontinence. Synonyms: Bis[(1S)-1,2,3,4-tetrahydro-1-phenyl-2(1H)-isoquinolinyl]-methanone; Bis[(1S)-3,4-dihydro-1-phenyl-2(1H)-isoquinolinyl]-methanone. Grades: > 95%. CAS No. 1534326-81-2. Molecular formula: C31H28N2O. Mole weight: 444.58. | |
Solifenacin Succinate Quick inquiry Where to buy | Solifenacin is a competitive cholinergic receptor antagonist. Solifenacin succinate is a urinary antispasmodic of the antimuscarinic class. Uses: Urological agents. Synonyms: YM905; YM 905; YM-905. Grades: >98%. CAS No. 242478-38-2. Molecular formula: C23H26N2O2·C4H6O4. Mole weight: 480.55. | |
Solithromycin Quick inquiry Where to buy | Solithromycin (CAS 760981-83-7) is a novel ketolide antibiotic. Solithromycin (CAS 760981-83-7) can be used for anti-infection, and It is expected to be the first macrolide antibiotic available in intravenous, oral, and pediatric suspension formulations in over 20 years. Synonyms: CEM101; CEM101; CEM 101; OP1068; OP1068; OP 1068; Solithromycin. Grades: >98%. CAS No. 760981-83-7. Molecular formula: C43H65FN6O10. Mole weight: 845.01. | |
Somatostatin Quick inquiry Where to buy | Somatostatin is an endogenous peptide that inhibits the release of growth hormone, insulin and glucagon. Somatostatin also blocks voltage-dependent calcium channels. Uses: Hormones. Synonyms: Somatostatin 14; Somatostatin-14; Panhibin; Somiaton. Grades: 98%. CAS No. 51110-01-1. Molecular formula: C76H104N18O19S2. Mole weight: 1637.88. | |
Sorafenib-beta-D-Glucuronide Quick inquiry Where to buy | Sorafenib-beta-D-Glucuronide is one of Sorafenib metabolites. Sorafenib is a polykinase inhibitor of Raf-1, B-Raf and VEGFR-2 and is an anti-tumor drug. Synonyms: N-[4-Chloro-3-(trifluoromethyl)phenyl]-N-[(4-{[2-(methylcarbamoyl)pyridin-4-yl]oxy}phenyl)carbamoyl]-beta-D-glucopyranuronosylamine; 1- [ [4-Chloro-3- (trifluoroMethyl) phenyl] [ [ [4- [ [2- [ (MethylaMino) carbonyl] -4-pyridinyl] oxy] phenyl] aMino] carbonyl] aMino] -1-deoxy-Beta-D-glucopyranuronic Acid; Sorafenib Beta-D-Glucuronide. Grades: ≥95%. CAS No. 1130164-93-0. Molecular formula: C27H24ClF3N4O9. Mole weight: 640.95. | |
Sorafenib Hemitosylate Quick inquiry Where to buy | Sorafenib Hemitosylate is the salt of Sorafenib, which is a kinase inhibitor drug used for the treatment of primary kidney cancer (advanced renal cell carcinoma), advanced primary liver cancer (hepatocellular carcinoma), FLT3-ITD positive AML and radioactive iodine resistant advanced thyroid carcinoma. Synonyms: 4-[4-[[[[4-chloro-3- (trifluoromethyl) phenyl]amino]carbonyl]amino] phenoxy]-N-methyl-2-pyridinecarboxamide, 4-methylbenzenesulfonate (2:1). CAS No. 2056030-06-7. Molecular formula: C21H16ClF3N4O3.1/2(C7H8O3S). Mole weight: 550.92. | |
Sorafenib related compound 10 Quick inquiry Where to buy | An impurity of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Synonyms: 4-[4-[[[[4-Chloro-3- (trifluoromethyl) phenyl]amino]carbonyl]amino]phenoxy]-2-pyridinecarboxylic Acid; 4- (4- (3- (4-Chloro-3- (trifluoromethyl) phenyl) ureido) phenoxy) picolinic Acid; Sorafenib Hydroxydemethylamine. Grades: > 95%. CAS No. 1012058-78-4. Molecular formula: C20H13ClF3N3O4. Mole weight: 451.79. | |
Sorafenib Related Compound 15 Quick inquiry Where to buy | An impurity of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Synonyms: 4,4'-[Carbonylbis(imino-4,1-phenyleneoxy)]bis[N-methyl-2-pyridinecarboxamide]; PAPE-urea; N,N'-Bis[4-[2-(N-methylcarbamoyl)-4-pyridyloxy]phenyl]urea. Grades: > 95%. CAS No. 284670-98-0. Molecular formula: C27H24N6O5. Mole weight: 512.53. | |
Sorafenib related compound 2 Quick inquiry Where to buy | An impurity of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Synonyms: N-[4-Chloro-3-(trifluoromethyl)phenyl]carbamic Acid Ethyl Ester; [4-Chloro-3-(trifluoromethyl)phenyl]carbamic Acid Ethyl Ester; 4-Chloro-3-(trifluoromethyl)carbanilic Acid Ethyl Ester; Ethyl (4-Chloro-3-(trifluoromethyl)phenyl)carbamate. Grades: > 95%. CAS No. 18585-06-3. Molecular formula: C10H9ClF3NO2. Mole weight: 267.64. | |
Sotalol hydrochloride Quick inquiry Where to buy | Sotalol hydrochloride is a non-selective beta adrenoceptor antagonist and potassium channel blocker (IC50 = 43 μM). Synonyms: Sotalol HCl. Grades: >98%. CAS No. 959-24-0. Molecular formula: C12H21ClN2O3S. Mole weight: 308.82. | |
Sparsentan (RE-021) Quick inquiry Where to buy | Sparsentan, also known as RE-021, BMS346567, is a dual antagonist of both angiotensin II and endothelin A receptor antagonist. Synonyms: 2-[4-[(2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-2-(ethoxymethyl)phenyl]-N-(4,5-dimethyl-1,2-oxazol-3-yl)benzenesulfonamide; RE-021; RE021; RE 021; PS-433540; PS433540; PS 433540; DARA-a; Sparsentan. Grades: >98%. CAS No. 254740-64-2. Molecular formula: C32H40N4O5S. Mole weight: 592.75. | |
SPDP Quick inquiry Where to buy | SPDP is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups. Uses: A heterobifunctional cross-linker. Synonyms: N-Succinimidyl 3-(2-Pyridyldithio)Propionate; UNII-2OHG8V08NL; SPDP NHS Ester; 3-(2-Pyridyldithio)Propionic Acid N-Hydroxysuccinimide Ester. Grades: ≥ 97% (HPLC). CAS No. 68181-17-9. Molecular formula: C12H12N2O4S2. Mole weight: 312.37. | |
SPHINX31 Quick inquiry Where to buy | SPHINX31 is a potent and selective inhibitor of serine/arginine-rich protein kinase 1 (SRPK1) (IC50 value of 6 nM). It inhibits SRPK1 activity and phosphorylation of serine/arginine splicing factor 1 (SRSF1), increasing expression of the anti-angiogenic VEGF-A165b splice variant in retinal pigment epithelial (RPE) cells. Synonyms: SPHINX31; SPHINX-31; SPHINX 31; 5-(4-pyridinyl)-N-[2-[4-(2-pyridinylmethyl)-1-piperazinyl]-5-(trifluoromethyl)phenyl]-2-furancarboxamide. Grades: 99%. CAS No. 1818389-84-2. Molecular formula: C27H24F3N5O2. Mole weight: 507.51. | |
SPI 112 Quick inquiry Where to buy | SPI 112 is a Shp2 PTP inhibitor. Synonyms: SPI-112; SPI112; SPI 112. 3-[2-[5-[(4-fluorophenyl)methylsulfamoyl]-2-oxoindol-3-yl]hydrazinyl]benzoic acid. CAS No. 1051387-90-6. Molecular formula: C22H17FN4O5S. Mole weight: 468.459. | |
SPI-112Me Quick inquiry Where to buy | SPI-112Me is a Shp2 PTP inhibitor. Synonyms: methyl 3-[2-[5-[(4-fluorophenyl)methylsulfamoyl]-2-oxoindol-3-yl]hydrazinyl]benzoate. CAS No. 1243685-62-2. Molecular formula: C23H19FN4O5S. Mole weight: 482.486. | |
(S)-Praziquantel Quick inquiry Where to buy | S configuration of Praziquantel.Praziquantel can be used for the treatment of a number of types of parasitic worm infections. Specifically it is used for schistosomiasis, clonorchiasis, opisthorchiasis, tapeworm infections, cysticercosis, hydatid disease, and other fluke infections. Grades: > 95%. CAS No. 57452-97-8. Molecular formula: C19H24N2O2. Mole weight: 312.42. | |
(S)-quinuclidin-3-amine Quick inquiry Where to buy | (S)-Quinuclidin-3-amine is an intermediate in the synthesis of Palonosetron, which is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Synonyms: (3S)-Aminoquinuclidine; (S)-1-Azabicyclo[2.2.2]oct-3-ylamine; (S)-3-Amino-1-azabicyclo[2.2.2]octane; (S)-3-Aminoquinuclidine; (S)-(-)-3-Aminoquinuclidine; (S)-1-Azabicyclo[2.2.2]octan-3-amine. Grades: 95%. CAS No. 120570-05-0. Molecular formula: C7H14N2. Mole weight: 126.20. | |
SR 18292 Quick inquiry Where to buy | SR 18292 is an inhibitor of peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α). It reduces blood glucose, potently increases hepatic insulin sensitivity, and improves glucose homeostasis in dietary and genetic mouse models of type 2 diabetes. Synonyms: 1-[Tert-butyl-[(4-methylphenyl)methyl]amino]-3-(1H-indol-4-yloxy)propan-2-ol. Grades: ≥95%. CAS No. 2095432-55-4. Molecular formula: C23H30N2O2. Mole weight: 366.5. | |
SR3335 Quick inquiry Where to buy | The retinoic acid receptor-related receptors (RORs) are orphan nuclear receptors with diverse putative roles. SR 3335 is a selective inverse agonist of RORα, competitively inhibiting the binding of 25-hydroxycholesterol to the ligand binding domain (Ki = 220 nM) and inhibiting constitutive transactivation activity (IC50 = 480 nM). It has no effect on RORβ, RORγ, farnesoid X receptor, or liver X receptor &alpha. SR 3335 evokes RORα-dependent effects both in vitro and in vivo, altering gene expression as well as gluconeogenesis. Synonyms: ML-176; SR 3335; SR-3335; ML176; ML 176. Grades: >98%. CAS No. 293753-05-6. Molecular formula: C13H9F6NO3S2. Mole weight: 405.34. | |
SR9011 Quick inquiry Where to buy | SR9011, a synthetic REV-ERB agonist, has been found to have probable effect against sleep disorders and metabolic diseases. IC50: 790 nM and 560 nM for Rev-ErbBα and Rev-ErbBβ respectively. Synonyms: SR 9011; SR-9011; 1-Pyrrolidinecarboxamide, 3-((((4-chlorophenyl)methyl)((5-nitro-2-thienyl)methyl)amino)methyl)-n-pentyl-. Grades: 98%. CAS No. 1379686-29-9. Molecular formula: C23H31ClN4O3S. Mole weight: 479.04. | |
(S)-Ranolazine Quick inquiry Where to buy | (S)-Ranolazine is the S-isomer of Ranolazine, which is a medication used to treat heart-related chest pain. Synonyms: 1-Piperazineacetamide, N-(2,6-dimethylphenyl)-4-[(2S)-2-hydroxy-3-(2-methoxyphenoxy)propyl]-; N-(2,6-Dimethylphenyl)-2-{4-[(2S)-2-hydroxy-3-(2-methoxyphenoxy)propyl]-1-piperazinyl}acetamide; (-)-Ranolazine. Grades: ≥95%. CAS No. 114246-81-0. Molecular formula: C24H33N3O4. Mole weight: 427.54. | |
S, R-Isovalganciclovir Impurity Quick inquiry Where to buy | S, R-Isovalganciclovir Impurity is an impurity of Valganciclovir. Synonyms: (R,S)-Iso Valganciclovir; (R)-[(S)-3-[(2-Amino-6-oxo-1,6-dihydropurin-9-yl)methoxy)-2-hydroxypropyl)-2,3-dimethylbutanoate. Grades: > 95%. CAS No. 1356932-18-7. Molecular formula: C14H22N6O5. Mole weight: 354.36. | |
Srpin340 Quick inquiry Where to buy | Srpin340 is an isonicotinamide compound that inhibits SRPK1 (Ki = 0.89 μM). It is about 10-fold less effective against SRPK2 and does not inhibit the related SRPKs, Clk1 and Clk4. Srpin340 suppresses the propagation of Sindbis virus in Vero cells and the replication of hepatitis C virus in Huh7/Rep-Feo-2a cells. Synonyms: SRPIN-340; SRPIN 340. Grades: 99.82%. CAS No. 218156-96-8. Molecular formula: C18H18F3N3O. Mole weight: 349.35. |