BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Selinexor | Selinexor is a potent and selective inhibitor of chromosome region maintenance 1 protein/exportin 1 (CRM1/XPO1). Selinexor was studied to show in vivo anti-leukaemic efficacy against T-ALL and acute myeloid leukaemia (AML) cells. Synonyms: KPT-330; KPT 330; KPT330; 2-Propenoic acid, 3-[3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]-, 2-(2-pyrazinyl)hydrazide, (2Z)-; Xpovio; (Z)-3-(3-(3,5-Bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-N'-(pyrazin-2-yl)acrylohydrazide; (2Z)-3-[3-[3,5-Bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]-2-propenoic acid 2-(2-pyrazinyl)hydrazide. Grades: ≥95%. CAS No. 1393477-72-9. Molecular formula: C17H11F6N7O. Mole weight: 443.31. |  |
| Selumetinib | Selumetinib, also known as AZD6244, is an orally bioavailable small molecule with potential antineoplastic activity. Selumetinib inhibits mitogen-activated protein kinase kinases (MEK or MAPK/ERK kinases) 1 and 2, which may prevent the activation of MEK1/2-dependent effector proteins and transcription factors, and so may inhibit cellular proliferation in MEK-overexpressing tumor cells. MEK 1 and 2 are dual-specificity kinases that are essential mediators in the activation of the RAS/RAF/MEK/ERK pathway, are often upregulated in various tumor cell types, and are drivers of diverse cellular activities, including cellular proliferation. Check for active clinical trials or closed clinical trials using this agent. Synonyms: ARRY-142886; ARRY 142886; ARRY142886; AZD6244; AZD-6244; AZD 6244; ARRY-886; ARRY886; ARRY 886. Grades: >98%. CAS No. 606143-52-6. Molecular formula: C17H15BrClFN4O3. Mole weight: 457.684. | |
| Semaglutide-[d15] | Semaglutide-[d15] is the labelled analogue of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Semaglutide-d15; H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val(D8)-Ser-Ser-Tyr-Leu(D7)-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH. Molecular formula: C187H276D15N45O59. Mole weight: 4128.73. | |
| Semaglutide Impurity 10 | Semaglutide Impurity 10 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Molecular formula: C188H291N45O61. Mole weight: 4157.65. | |
| Semaglutide Impurity 11 | Semaglutide Impurity 11 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Molecular formula: C187H291N43O59. Mole weight: 4085.63. | |
| Semaglutide Impurity 12 | Semaglutide Impurity 12 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: 3,6-Dioxa-9,14-diazadotriacontanedioic acid, 13-[(1,1-dimethylethoxy)carbonyl]-10,15-dioxo-, 32-(1,1-dimethylethyl) ester, (13R)-; 32-(1,1-Dimethylethyl) (13R)-13-[(1,1-dimethylethoxy)carbonyl]-10,15-dioxo-3,6-dioxa-9,14-diazadotriacontanedioate. Molecular formula: C37H68N2O10. Mole weight: 700.96. | |
| Semaglutide Impurity 13 | Semaglutide Impurity 13 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: 3,6,12,15-Tetraoxa-9-azaheptadecan-1-oic acid, 17-[[(4R)-5-(1,1-dimethylethoxy)-4-[[18-(1,1-dimethylethoxy)-1,18-dioxooctadecyl]amino]-1,5-dioxopentyl]amino]-10-oxo-; (22R)-43,43-Dimethyl-22-{[(2-methyl-2-propanyl)oxy]carbonyl}-10,19,24,41-tetraoxo-3,6,12,15,42-pentaoxa-9,18,23-triazatetratetracontan-1-oic acid; 3,6,12,15-Tetraoxa-9,18,23-triazahentetracontanedioic acid, 22-[(1,1-dimethylethoxy)carbonyl]-10,19,24-trioxo-, 41-(1,1-dimethylethyl) ester, (22R)-; 41-(1,1-Dimethylethyl) (22R)-22-[(1,1-dimethylethoxy)carbonyl]-10,19,24-trioxo-3,6,12,15-tetraoxa-9,18,23-triazahentetracontanedioate. Molecular formula: C43H79N3O13. Mole weight: 846.11. | |
| Semaglutide Impurity 14 | Semaglutide Impurity 14 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Molecular formula: C43H80N4O12. Mole weight: 845.13. | |
| Semaglutide Impurity 15 | Semaglutide Impurity 15 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Molecular formula: C49H90N4O16. Mole weight: 991.27. | |
| Semaglutide Impurity 16 | Semaglutide Impurity 16 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Glycine, N-L-α-glutamyl-, 5-(1,1-dimethylethyl) ester; Glutaramic acid, 4-amino-N-(carboxymethyl)-, 1-tert-butyl ester, L-; (S)-(2-amino-5-(tert-butoxy)-5-oxopentanoyl)glycine; H-Glu(OtBu)-Gly-OH; ({(2S)-2-Amino-5-[(2-methyl-2-propanyl)oxy]-5-oxopentanoyl}amino)acetic acid. CAS No. 23406-82-8. Molecular formula: C11H20N2O5. Mole weight: 260.29. | |
| Semaglutide Impurity 17 | Semaglutide Impurity 17 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Molecular formula: C23H33N3O8. Mole weight: 479.53. | |
| Semaglutide Impurity 18 | Semaglutide Impurity 18 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Molecular formula: C15H27N3O6. Mole weight: 345.40. | |
| Semaglutide Impurity 19 | Semaglutide Impurity 19 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Molecular formula: C46H58N6O9. Mole weight: 839.00. | |
| Semaglutide Impurity 1 ((Trp25-hydroxybenzyl)-Semaglutide) | Semaglutide Impurity 1 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: L-Histidyl-2-methylalanyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[N-(17-carboxy-1-oxoheptadecyl)-L-γ-glutamyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-2-[2-(2-aminoethoxy)ethoxy]acetyl]-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-(L-tryptophyl-hydroxybenzyl)-L-leucyl-L-valyl-L-arginylglycyl-L-arginylglycine; H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-(Trp-hydroxybenzyl)-Leu-Val-Arg-Gly-Arg-Gly-OH. Molecular formula: C194H297N45O60. Mole weight: 4219.77. | |
| Semaglutide Impurity 2 | Semaglutide Impurity 2 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Na-(((9H-fluoren-9-yl)methoxy)carbonyl)-1-(4-((tert-butyldiphenylsilyl)oxy)benzyl)-L-tryptophan. Molecular formula: C49H46N2O5Si. Mole weight: 771.00. | |
| Semaglutide Impurity 20 | Semaglutide Impurity 20 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Molecular formula: C41H48N6O9. Mole weight: 768.87. | |
| Semaglutide Impurity 21 | Semaglutide Impurity 21 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. CAS No. 2377584-78-4. Molecular formula: C26H42N6O9. Mole weight: 582.66. | |
| Semaglutide Impurity 22 | Semaglutide Impurity 22 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Molecular formula: C45H56N6O9. Mole weight: 824.98. | |
| Semaglutide Impurity 23 | Semaglutide Impurity 23 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Molecular formula: C49H63N7O10. Mole weight: 910.08. | |
| Semaglutide Impurity 3 (P3 Semaglutide) | Semaglutide Impurity 3 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[N-(17-carboxy-1-oxoheptadecyl)-L-γ-glutamyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-2-[2-(2-aminoethoxy)ethoxy]acetyl]-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginylglycine; H-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH. Molecular formula: C126H206N30O36. Mole weight: 2717.21. | |
| Semaglutide Impurity 4 (U7 Semaglutide) | Semaglutide Impurity 4 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Molecular formula: C29H51N5O14. Mole weight: 693.75. | |
| Semaglutide Impurity 5 (U6 Semaglutide) | Semaglutide Impurity 5 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Molecular formula: C27H47N5O14. Mole weight: 665.69. | |
| Semaglutide Impurity 6 | Semaglutide Impurity 6 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: 3,6-Dioxa-9,14-diazadotriacontanedioic acid, 13-[(1,1-dimethylethoxy)carbonyl]-10,15-dioxo-, 32-(1,1-dimethylethyl) ester, (13S)-; 32-(1,1-Dimethylethyl) (13S)-13-[(1,1-dimethylethoxy)carbonyl]-10,15-dioxo-3,6-dioxa-9,14-diazadotriacontanedioate. CAS No. 1671100-14-3. Molecular formula: C37H68N2O10. Mole weight: 700.96. | |
| Semaglutide Impurity 7 | Semaglutide Impurity 7 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. It is also an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. Synonyms: 1-tert-Butyl 18-(2,5-dioxopyrrolidin-1-yl) octadecanedioate; Boc-C16-NHS ester; t-butyl-octadecanedioate-NHS ester; Succinimidyl tert-butyl octadecandioate; Octadecanedioic acid tert-butyl ester 2,5-dioxopyrrolidin-1-yl ester; Octadecanedioic acid, 1-(1,1-dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) ester; 1-(1,1-Dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) octadecanedioate; Octadecanoic acid, 18-[(2,5-dioxo-1-pyrrolidinyl)oxy]-18-oxo-, 1,1-dimethylethyl ester; 18-tert-Butoxy-18-oxooctadecanoic acid succinimidyl ester. CAS No. 843666-34-2. Molecular formula: C26H45NO6. Mole weight: 467.65. | |
| Semaglutide Impurity 8 | Semaglutide Impurity 8 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: L-Glutamic acid, N-[18-(1,1-dimethylethoxy)-1,18-dioxooctadecyl]-, 1-(1,1-dimethylethyl) 5-(2,5-dioxo-1-pyrrolidinyl) ester; 1-(1,1-Dimethylethyl) 5-(2,5-dioxo-1-pyrrolidinyl) N-[18-(1,1-dimethylethoxy)-1,18-dioxooctadecyl]-L-glutamate; (S) -2- (17-tert-Butoxycarbonylheptadecanoylamino) pentanedioic acid 1-tert-butyl ester 5-(2,5-dioxopyrrolidin-1-yl) ester; 5-(2,5-Dioxo-1-pyrrolidinyl) 1-(2-methyl-2-propanyl) N-{18-[(2-methyl-2-propanyl)oxy]-18-oxooctadecanoyl}-L-glutamate; N-[18-(1,1-Dimethylethoxy)-1,18-dioxooctadecyl]-L-glutamic acid 1-(1,1-dimethylethyl) 5-(2,5-dioxo-1-pyrrolidinyl) ester. Grades: ≥95%. CAS No. 1188328-22-4. Molecular formula: C35H60N2O9. Mole weight: 652.87. | |
| Semaglutide Impurity 9 | Semaglutide Impurity 9 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: L-2-oxo-Histidyl-2-methylalanyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[N-(17-carboxy-1-oxoheptadecyl)-L-γ-glutamyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-2-[2-(2-aminoethoxy)ethoxy]acetyl]-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginylglycine; (2-oxo-His)-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH. Molecular formula: C187H289N45O60. Mole weight: 4127.62. | |
| Semaglutide-[Phe-d5] | Semaglutide-[Phe-d5] is the labelled analogue of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: H-His-Aib-Glu-Gly-Thr-Phe(D5)-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH; Semaglutide D5; Semaglutide-d5. Molecular formula: C187H286D5N45O59. Mole weight: 4118.67. | |
| Semaglutide-[Phe-d8] | Semaglutide-[Phe-d8] is the labelled analogue of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: H-His-Aib-Glu-Gly-Thr-Phe(D8)-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH; Semaglutide D8; Semaglutide-d8. Molecular formula: C187H283D8N45O59. Mole weight: 4121.69. | |
| Semaglutide related compound 1 | Semaglutide related compound 1 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Semaglutide SZ Impurity 1; Semaglutide Iso Asp Impurity; H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Iso-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH. Molecular formula: C187H291N45O59. Mole weight: 4113.64. | |
| Semaglutide related compound 10 | Semaglutide related compound 10 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Semaglutide SZ Impurity 10. Molecular formula: C190H295N47O61. Mole weight: 4213.72. | |
| Semaglutide related compound 11 | Semaglutide related compound 11 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Semaglutide SZ Impurity 11. Molecular formula: C187H290N46O61. Mole weight: 4158.64. | |
| Semaglutide related compound 12 | Semaglutide related compound 12 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Semaglutide SZ Impurity 12. Molecular formula: C188H290N46O61. Mole weight: 4170.65. | |
| Semaglutide related compound 13 | Semaglutide related compound 13 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Semaglutide SZ Impurity 13. Molecular formula: C187H290N46O62. Mole weight: 4174.64. | |
| Semaglutide related compound 14 | Semaglutide related compound 14 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Semaglutide SZ Impurity 14. Molecular formula: C189H294N46O60. Mole weight: 4170.69. | |
| Semaglutide related compound 15 | Semaglutide related compound 15 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Semaglutide SZ Impurity 15. Molecular formula: C189H294N46O60. Mole weight: 4170.69. | |
| Semaglutide related compound 16 | Semaglutide related compound 16 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Semaglutide SZ Impurity 16. Molecular formula: C189H294N46O60. Mole weight: 4170.69. | |
| Semaglutide related compound 17 | Semaglutide related compound 17 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Semaglutide SZ Impurity 17. Molecular formula: C189H292N46O59. Mole weight: 4152.68. | |
| Semaglutide related compound 18 | Semaglutide related compound 18 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Semaglutide SZ Impurity 18. Molecular formula: C186H288N46O58. Mole weight: 4096.61. | |
| Semaglutide related compound 19 | Semaglutide related compound 19 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Semaglutide SZ Impurity 19. Molecular formula: C185H286N46O58. Mole weight: 4082.59. | |
| Semaglutide related compound 2 | Semaglutide related compound 2 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Semaglutide SZ Impurity 2; H-His-Aib-Glu-Gly-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH; Des-Thr(5)-Semaglutide; Semaglutide Des Thr-11 Impurity. Molecular formula: C183H284N44O57. Mole weight: 4012.54. | |
| Semaglutide related compound 3 | Semaglutide related compound 3 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Semaglutide SZ Impurity 3; Semaglutide Plus 106 Impurity; H-D-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-(Trp-2-hydroxybenzyl)-Leu-Val-Arg-Gly-Arg-Gly-OH. Molecular formula: C194H297N45O60. Mole weight: 4219.77. | |
| Semaglutide related compound 4 | Semaglutide related compound 4 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Semaglutide SZ Impurity 4; Semaglutide Endo Gly-10 Impurity; Endo-Gly(4)-Semaglutide; Endo-Gly(10)-Semaglutide; L-Histidyl-2-methylalanyl-L-α-glutamylglycylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[N-(17-carboxy-1-oxoheptadecyl)-L-γ-glutamyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-2-[2-(2-aminoethoxy)ethoxy]acetyl]-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginylglycine; H-His-Aib-Glu-Gly-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH. Molecular formula: C189H294N46O60. Mole weight: 4170.69. | |
| Semaglutide related compound 6 | Semaglutide related compound 6 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Semaglutide SZ Impurity 6; Semaglutide D-His-7 Impurity; D-His(7)-Semaglutide; D-His(1)-Semaglutide; D-Histidyl-2-methylalanyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[N-(17-carboxy-1-oxoheptadecyl)-L-γ-glutamyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-2-[2-(2-aminoethoxy)ethoxy]acetyl]-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginylglycine; H-D-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH. Molecular formula: C187H291N45O59. Mole weight: 4113.64. | |
| Semaglutide related compound 8 | Semaglutide related compound 8 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Semaglutide SZ Impurity 8. Molecular formula: C188H292N46O60. Mole weight: 4156.67. | |
| Semaglutide related compound 9 | Semaglutide related compound 9 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Semaglutide SZ Impurity 9. Molecular formula: C190H295N47O61. Mole weight: 4213.72. | |
| Semaglutide-[Val-d8] Tetratrifluoroacetate | Semaglutide-[Val-d8] Tetratrifluoroacetate is the labelled salt of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Semaglutide-d8 Tetratrifluoroacetate; L-histidyl-2-methylalanyl-L-a-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-a-aspartyl-L-valyl-d8-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-a-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[N-(17-carboxy-1-oxoheptadecyl)-L-a-glutamyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-2-[2-(2-aminoethoxy)ethoxy]acetyl]-L-lysyl-L-a-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginyl-Glycine, trifluoroacetic acid (1:4); H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val(D8)-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH.4TFA. Molecular formula: C187H283D8N45O59.4C2HF3O2. Mole weight: 4577.78. | |
| Semax | Semax is a peptide analog of adrenocorticotropic hormone (ACTH) (4-10). ACTH is a tropic hormone produced by the anterior pituitary. Uses: Enzyme inhibitors. Synonyms: H-Met-Glu-His-Phe-Pro-Gly-Pro-OH; L-Proline, L-methionyl-L-α-glutamyl-L-histidyl-L-phenylalanyl-L-prolylglycyl-; L-Methionyl-L-α-glutamyl-L-histidyl-L-phenylalanyl-L-prolylglycyl-L-proline; L-Proline, 1-[N-[1-[N-[N-(N-L-methionyl-L-α-glutamyl)-L-histidyl]-L-phenylalanyl]-L-prolyl]glycyl]-; ACTH (4-7), Pro-Gly-Pro-; Pro-gly-pro-ACTH (4-7). Grades: 98%. CAS No. 80714-61-0. Molecular formula: C37H51N9O10S. Mole weight: 813.92. | |
| Semaxanib | Semaxanib is a quinolone derivative with potential antineoplastic activity. Semaxanib reversibly inhibits ATP binding to the tyrosine kinase domain of vascular endothelial growth factor receptor 2 (VEGFR2), which may inhibit VEGF-stimulated endothelial cell migration and proliferation and reduce the tumor microvasculature. This agent also inhibits the phosphorylation of the stem cell factor receptor tyrosine kinase c-kit, often expressed in acute myelogenous leukemia cells. Uses: Angiogenesis inhibitors. Synonyms: SU5416; SU-5416; SU 5416; Sugen 5416; semoxind. Grades: 98%. CAS No. 204005-46-9. Molecular formula: C15H14N2O. Mole weight: 238.28. | |
| (S,E)-methyl 2-(5-(cyanoimino)-1-propylpyrrolidin-2-yl)acetate | An impurity of Pramipexole which is an agonist of dopamine receptor D2, D3 and D4, especially used as D2-receptor agonist. Synonyms: rac N-Propyl-2-cyanimidopyrrolidine-5-acetic Acid Methyl Ester; Pramipexole Impurity 16. Grades: 99%. CAS No. 1373869-91-0. Molecular formula: C11H17N3O2. Mole weight: 223.27. | |
| Se-(Methyl)selenocysteine hydrochloride | Se-(Methyl)selenocysteine hydrochloride is an anticancer agent that inhibits cell cycle proliferation and induces apoptosis. Synonyms: (2R)-2-amino-3-methylselanylpropanoic acid hydrochloride; (R)-2-Amino-3-(methylselanyl)propanoic acid hydrochloride; Se-MSC. Grades: >95%. CAS No. 863394-07-4. Molecular formula: C4H10ClNO2Se. Mole weight: 218.55. | |
| (S,E)-N-(4-((3,4-Difluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: 4-(Dimethylamino)but-2-enamide, (S,E)-N-(4-((3,4-difluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-; Afatinib Difluoro Analog; Afatinib Impurity SF. Grades: ≥95%. CAS No. 2223677-62-9. Molecular formula: C24H25F2N5O3. Mole weight: 469.48. | |
| (S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(methylamino)but-2-enamide | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: 2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(methylamino)-, (2E)-; Afatinib Impurity YJA. Grades: ≥95%. CAS No. 2413212-13-0. Molecular formula: C23H23ClFN5O3. Mole weight: 471.91. | |
| Senicapoc | Senicapoc, previously called as ICA 17043, is a small organic potent and selective blocker of the Gardos channel which is the calcium-activated potassium channel located on the human RBC, inhibiting the efflux of K+ through this channel. Synonyms: 2,2-bis(4-fluorophenyl)-2-phenylacetamide; bis(4-fluorophenyl)phenylacetamide; ICA 17043; ICA-17043; ICA17043. CAS No. 289656-45-7. Molecular formula: C20H15F2NO. Mole weight: 323.34. | |
| [SER140]-PLP(139-151) | PLP(139-151), a synthetic myelin proteolipid protein (PLP) fragment, induces experimental autoimmune encephalomyelitis (EAE). Synonyms: H-His-Ser-Leu-Gly-Lys-Trp-Leu-Gly-His-Pro-Asp-Lys-Phe-OH; L-histidyl-L-seryl-L-leucyl-glycyl-L-lysyl-L-tryptophyl-L-leucyl-glycyl-L-histidyl-L-prolyl-L-alpha-aspartyl-L-lysyl-L-phenylalanine; Proteolipid protein (139-151); PLP(139-151). Grades: ≥97% by HPLC. CAS No. 122018-58-0. Molecular formula: C72H104N20O17. Mole weight: 1521.72. | |
| Ser(Ac)5-Calcitonin | Ser(Ac)5-Calcitonin is an impurity of Calcitonin salmon, which is a calcium regulating hormone used to be an effective alternative for the treatment of postmenopausal osteoporosis. Synonyms: H-Cys-Ser-Asn-Leu-Ser(Ac)-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2 (Disulfide bond between Cys1 and Cys7); Calcitonin EP impurity D. Molecular formula: C147H242N44O49S2. Mole weight: 3473.93. | |
| Seractide acetate | ACTH (1-39) is a potent agonist of melanocortin receptor 2 (MC2R) with an EC50 value of 57 pM in HeLa cells expressing the mouse receptor. Synonyms: 1-39-Corticotropin (human) (TFA); α(1-39) Corticotropin human (TFA); Acth, human (TFA); Adrenocorticotropic hormone, human (TFA); ACTH (1-39) (TFA); ACTH (1-39) trifluoroacetate salt; Adrenocorticotropic Hormone (ACTH) (1-39), human (TFA); Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-Asn-Gly-Ala-Glu-Asp-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe.TFA. Grades: >98%. CAS No. 12279-41-3. Molecular formula: C207H308N56O58S.C2HF3O2. Mole weight: 4655.16. | |
| Sergliflozin etabonate | Sergliflozin etabonate is a SGLT-2 inhibitor as a promising agent for the type 2 diabetes and obesity treatment. Synonyms: 2-(4-Methoxybenzyl)phenyl6-O-(ethoxycarbonyl)-beta-D-glucopyranoside. Grades: 95%. CAS No. 408504-26-7. Molecular formula: C23H28O9. Mole weight: 448.46. | |
| Serlopitant | Serlopitant is a Neurokinin 1 (NK-1) receptor antagonist. Phase II clinical trials for the treatment of Prurigo nodularis and Pruritus are ongoing. Uses: Prurigo nodularis; pruritus. Synonyms: VPD-737; VPD737; VPD 737; MK-0594; MK 0594; MK0594; 3-((3aR,4R,5S,7aS)-5-((1R)-1-(3,5-bis(Trifluoromethyl)phenyl)ethoxy)-4-(4 fluorophenyl)octahydro-2H-isoindol-2-yl)cyclopent-2-en-1-one. Grades: 98%. CAS No. 860642-69-9. Molecular formula: C29H28F7NO2. Mole weight: 555.53. | |
| Sermorelin acetate | Sermorelin acetate is a growth hormone-releasing hormone (GHRH) analogue composed of 29 amino acids. It is recognized as the shortest fully functional fragment of GHRH. It is used as a diagnostic agent to assess growth hormone (GH) secretion. Meanwhile, it is also used as a doping agent in sports due to its correlation with increased growth of muscular and skeletal tissue. Synonyms: 1-29-Somatoliberin (human pancreatic islet), 29-L-argininamide-, acetate (1:x); H-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2.CH3CO2H; L-tyrosyl-L-alanyl-L-alpha-aspartyl-L-alanyl-L-isoleucyl-L-phenylalanyl-L-threonyl-L-asparagyl-L-seryl-L-tyrosyl-L-arginyl-L-lysyl-L-valyl-L-leucyl-glycyl-L-glutaminyl-L-leucyl-L-seryl-L-alanyl-L-arginyl-L-lysyl-L-leucyl-L-leucyl-L-glutaminyl-L-alpha-aspartyl-L-isoleucyl-L-methionyl-L-seryl-L-argininamide acetic acid. Grades: ≥95%. CAS No. 516482-86-3. Molecular formula: C149H246N44O42S.xC2H4O2. Mole weight: 3357.88 (free base). | |
| Sertaconazole nitrate | Sertaconazole nitrate is a topical broad-spectrum antifungal that is developed to provide an additional agent for the treatment of superficial cutaneous and mucosal infections. Synonyms: FI-7045; FI 7045; FI7045. Grades: >98%. CAS No. 99592-39-9. Molecular formula: C20H15Cl3N2OS·HNO3. Mole weight: 500.78. | |
| (S)-Esmolol Acid | (S)-Esmolol Acid is an impurity of Esmolol. Esmolol is a cardioselective β-blocker which has a rapid onset but short duration of action without causing significant intrinsic sympathomimetic or membrane stabilizing activities at recommended therapeutic doses. Synonyms: 4-[ (2S) -2-Hydroxy-3-[ (1-methylethyl) amino]propoxy]benzenepropanoic Acid. CAS No. 910651-36-4. Molecular formula: C15H23NO4. Mole weight: 281.35. | |
| (S)-Esmolol Hydrochloride | (S)-Esmolol Hydrochloride is an impurity of Esmolol. Esmolol is a cardioselective β-blocker which has a rapid onset but short duration of action without causing significant intrinsic sympathomimetic or membrane stabilizing activities at recommended therapeutic doses. Uses: The s-enantiomer of esmolol (e668000). Synonyms: 4-[ (2S) -2-Hydroxy-3-[ (1-methylethyl) amino]propoxy]benzenepropanoic Acid Methyl Ester Hydrochloride; (-)-Esmolol Hydrochloride. Grades: >95%. CAS No. 112923-91-8. Molecular formula: C16H25NO4.HCl. Mole weight: 331.83. | |
| Setmelanotide | Setmelanotide is a melanocortin 4 receptor (MC4R) agonist (EC50 = 0.27 nM for human MC4R) that is used as a peptide drug and investigational anti-obesity medication. Synonyms: RM-493; BIM-22493; IRC-022493. CAS No. 920014-72-8. Molecular formula: C49H68N18O9S2. Mole weight: 1117.31. | |
| (S)-Etodolac | An isomer of Etodolac. Etodolac is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2. Synonyms: (1S)-1,8-Diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic Acid. Grades: > 95%. CAS No. 87249-11-4. Molecular formula: C17H21NO3. Mole weight: 287.36. | |
| S-(-)-Etomidate | A stereoisomer of Etomidate. Etomidate is a short-acting intravenous anaesthetic agent used for the induction of general anaesthesia and sedation for short procedures such as reduction of dislocated joints, tracheal intubation, and cardioversion. Synonyms: 1-[(1S)-1-Phenylethyl]-1H-Imidazole-5-carboxylic Acid Ethyl Ester; (S)-1-(1-Phenylethyl)-,1H-imidazole-5-carboxylic Acid Ethyl Ester. Grades: > 95%. CAS No. 56649-47-9. Molecular formula: C14H16N2O2. Mole weight: 244.30. | |
| Sevelamer Carbonate | Sevelamer Carbonate is a non-absorbed phosphate binding crosslinked polymer. Uses: Chelating agents. Synonyms: KW-9144; KW 9144; KW9144. Grades: >98%. CAS No. 845273-93-0. Molecular formula: (C3H7N)m.(C3H5ClO)n.(CH2O3)x. Mole weight: 211.64. | |
| S-(+)-Flecainide | A stereoisomer of Flecainide. Flecainide is a class 1C antiarrhythmic drug especially used for the management of supraventricular arrhythmia. Synonyms: N-[(2S)-2-Piperidinylmethyl]-2,5-bis(2,2,2-trifluoroethoxy)benzamide; (S)-Flecainide; (+)-Flecainide. Grades: > 95%. CAS No. 99495-92-8. Molecular formula: C17H20F6N2O3. Mole weight: 414.35. | |
| (S)-Flurbiprofen | (S)-Flurbiprofen is the S-isomer of Flurbiprofen. Synonyms: Dexflurbiprofen; Esflurbiprofen; S-(+)-Flurbiprofen; d-Flurbiprofen; (+)-(S)-Flurbiprofen; (+)-Flurbiprofen; (2S)-2-(2-Fluoro-1,1'-biphenyl-4-yl)propanoic Acid; (2S)-2-(2-Fluoro-4-biphenyl)propanoic Acid. Grades: > 95%. CAS No. 51543-39-6. Molecular formula: C15H13FO2. Mole weight: 244.27. | |
| (S)-Flurbiprofen Axetil (Mixture of Diastereomers) | Synonyms: (S)-1-Acetoxyethyl 2-(2-fluoro-[1,1'-biphenyl]-4-yl)propanoate; 1401087-64-6. Grades: > 95%. CAS No. 1401087-64-6. Molecular formula: C19H19FO4. Mole weight: 330.36. | |
| (S)-Frovatriptan Succinate | Grades: > 95%. Molecular formula: C18H23N3O5. Mole weight: 361.40. | |
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