BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| (R)-5-(hydroxymethyl)-3-(4-morpholinophenyl)oxazolidin-2-one | (R)-5-(hydroxymethyl)-3-(4-morpholinophenyl)oxazolidin-2-one is an impurity of Linezolid, an oxazolidinone antimicrobial that is used to treat infections against gram-positive bacteria, especially those that are drug-resistant. Linezolid works by inhibiting bacterial protein synthesis. Synonyms: 3-(4-(4-Morpholinyl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one; Linezolid Impurity 22. CAS No. 264601-17-4. Molecular formula: C14H18N2O4. Mole weight: 278.30. |  |
| (R)-8-(1-acryloylpiperidin-3-yl)-10-(4-phenoxyphenyl)-3,4-dihydropyrazolo[4,3-e]pyrimido[1,2-c]pyrimidin-2(8H)-one | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Synonyms: Ibrutinib Impurity MDGH. Grades: ≥95%. CAS No. 1917333-91-5. Molecular formula: C28H26N6O3. Mole weight: 494.54. | |
| (R)-8-(3-aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione | An impurity of Linagliptin, a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes. Synonyms: 8-[(3R)-3-Amino-1-piperidinyl]-7-(2-butyn-1-yl)-3,7-dihydro-3-methyl-1H-purine-2,6-dione; Linagliptin Impurity C. Grades: ≥95%. CAS No. 1791405-13-4. Molecular formula: C15H20N6O2. Mole weight: 316.36. | |
| rac 1-[3,4-(Dibenzyloxy)phenyl]-2-bromo-1-butanone | Rac 1-[3,4-(Dibenzyloxy)phenyl]-2-bromo-1-butanone is an intermediate of α-Ethylnorepinephrine. Uses: Intermediate in the production of α-ethylnorepinephrine. Synonyms: 1-[3,4-Bis(phenylmethoxy)phenyl]-2-bromo-1-butanone; 3',4'-Bis(benzyloxy)-2-bromo-butyrophenone; 3,4-Dibenzyloxy-2-bromobutphenone. Grades: ≥90%. CAS No. 24538-60-1. Molecular formula: C24H23BrO3. Mole weight: 439.34. | |
| rac-(2,3)-Dihydro Tetrabenazine [Cis/Trans Mixture] | rac-(2,3)-Dihydro Tetrabenazine [Cis/Trans Mixture] is an impurity of Tetrabenazine, which is a VMAT inhibitor used in the treatment of hyperkinetic movement disorder. Synonyms: (2R,3S,11bS)-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol compd. with (2S,3S,11bS)-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol. Molecular formula: C19H29NO3. Mole weight: 319.44. | |
| rac-2-Amino Nicotine | Synonyms: (±)-3-(1-Methyl-2-pyrrolidinyl)-2-pyridinamine; (±)-2-Aminonicotine; NSC 68655. Grades: ≥95%. CAS No. 32726-84-4. Molecular formula: C10H15N3. Mole weight: 177.25. | |
| rac-3-Thienyl-duloxetine | Rac-3-Thienyl-duloxetine is an impurity of Duloxetine, which is a serotonin-norepinephrine reuptake inhibitor used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, neuropathic pain and central sensitization. Synonyms: Duloxetine Impurity 12; 3-Thiophenepropanamine, N,N-dimethyl-gamma-(1-naphthalenyloxy)-, ethanedioate(1:1); N,N-Dimethyl-γ-(1-naphthalenyloxy)-3-thiophenepropanamine Ethanedioate; N,N-Dimethyl-3-(1-naphthyloxy)-3-(3-thienyl)-1-propanamine ethanedioate (1:1). Grades: 95%. CAS No. 116817-26-6. Molecular formula: C21H23NO5S. Mole weight: 401.48. | |
| rac 4-Hydroxy-9-cis-retinoic Acid Methyl Ester | rac 4-Hydroxy-9-cis-retinoic Acid Methyl Ester is an intermediate in the synthesis of rac 4-Hydroxy-9-cis-retinoic Acid, which is a metabolite of 9-cis-Retinoic acid. Synonyms: (2E,4E,6Z,8E)-Methyl 9-(3-Hydroxy-2,6,6-trimethylcyclohex-1-en-1-yl)-3,7-dimethylnona-2,4,6,8-tetraenoate. Molecular formula: C21H30O3. Mole weight: 330.46. | |
| rac 8-Hydroxy Efavirenz | A metabolite of Efavirenz , a nonnucleoside HIV-1 reverse transcriptase inhibitor. Synonyms: 6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one. Grades: > 95%. CAS No. 205754-32-1. Molecular formula: C14H9ClF3NO3. Mole weight: 331.68. | |
| rac all-trans-13,14-Dihydro Retinoic Acid Ethyl Ester | rac all-trans-13,14-Dihydro Retinoic Acid Ethyl Ester is a dihydro ester derivative of all-trans Retinoic Acid. Synonyms: ethyl (4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-4,6,8-trienoate; Ethyl all-trans-13,14-Dihydro Retinoate. Molecular formula: C22H34O2. Mole weight: 330.50. | |
| rac all-trans 3-(Acetyloxy) Retinol Acetate | rac all-trans 3-(Acetyloxy) Retinol Acetate is a metabolite of all-trans Retinoic acid. Retinoic Acid is a metabolite of Vitamin A and ajusts its functions of cellular growth and differentiation. Uses: A metabolite of all-trans retinoic acid. Synonyms: 3-(Acetyloxy)-retinol Acetate. Grades: ≥95%. CAS No. 76686-33-4. Molecular formula: C24H34O4. Mole weight: 386.52. | |
| rac all-trans 3-Hydroxy Retinoic Acid Ethyl Ester | rac all-trans 3-Hydroxy Retinoic Acid Ethyl Ester is a derivative of all-trans Retinoic acid. Retinoic Acid is a metabolite of Vitamin A and ajusts its functions of cellular growth and differentiation. Synonyms: (±)-3-Hydroxy-retinoic Acid Ethyl Ester; Retinoic acid, 3-hydroxy-, ethyl ester, (±)-. Grades: ≥95%. CAS No. 120674-74-0. Molecular formula: C22H32O3. Mole weight: 344.49. | |
| rac-Anatabine HCl | rac-Anatabine HCl is one of Nicotine metabolites, which is a potent parasympathomimetic stimulant. Synonyms: 1,2,3,6-Tetrahydro-2,3'-bipyridine hydrochloride; 2,3'-Bipyridine, 1,2,3,6-tetrahydro-, hydrochloride (1:1); (±)-Anatabine hydrochloride; 1,2,3,6-Tetrahydro-2-(3-pyridyl)pyridine hydrochloride; 2-(3-Pyridyl)-1,2,3,6-tetrahydropyridine hydrochloride; DL-Anatabine hydrochloride. Molecular formula: C10H12N2.HCl. Mole weight: 196.68. | |
| rac-cis-7-Hydroxy pramipexole | An impurity of Pramipexole, which is a thiazole derivative usually used as a D2-receptor agonist. Synonyms: rac-cis-7-Hydroxy-Pramipexole; (6S,7S)-2-amino-6-(propylamino)-4,5,6,7-tetrahydrobenzo[d]thiazol-7-ol. Grades: 95%. CAS No. 1001648-71-0. Molecular formula: C10H17N3OS. Mole weight: 227.33. | |
| rac-cis-Dorzolamide | rac-cis Dorzolamide is an impurity of Dorzolamide. Synonyms: (4R,6S)-rel-4-(Ethylamino)-5,6-dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-Dioxide Monohydrochloride; cis-4-(Ethylamino)-5,6-dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-Dioxide Monohydrochloride. Grades: > 95%. CAS No. 120279-37-0. Molecular formula: C10H16N2O4S3. Mole weight: 324.44. | |
| rac-cis-Lamivudine Acid (1R,2S,5R)-5-Methyl-2-isopropylcyclohexyl Ester (Mixture of 2 Diastereomers) | rac-cis-Lamivudine Acid (1R,2S,5R)-5-Methyl-2-isopropylcyclohexyl Ester (Mixture of 2 Diastereomers) is a protected impurity of Lamivudine, which is a potent nucleoside reverse transcriptase inhibitor and antiviral agent used to treat chronic hepatitis B. Synonyms: (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl 5-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylate. CAS No. 1322623-20-0. Molecular formula: C18H27N3O4S. Mole weight: 381.49. | |
| rac,cis-Milnacipran Hydrochloride | Rac,cis-Milnacipran Hydrochloride is an impurity of Milnacipran, which is a serotonin-norepinephrine reuptake inhibitor (SNRI) used in the clinical treatment of fibromyalgia. Synonyms: Milnacipran Methyl Amine Impurity HCl; cis-N,N-Diethyl-2-[(methylamino)methyl]-1-phenyl-cyclopropanecarboxamide Monohydrochloride; cis-(±)-N,N-Diethyl-2-[(methylamino)methyl]-1-phenyl-cyclopropanecarboxamide Monohydrochloride; Milnacipran Methyl Amine Hydrochloride; (1R,2S)-N,N-Diethyl-2-[(methylamino)methyl]-1-phenylcyclopropanecarboxamide hydrochloride (1:1); Cyclopropanecarboxamide, N,N-diethyl-2-[(methylamino)methyl]-1-phenyl-, (1R,2S)-, hydrochloride (1:1). Grades: ≥95%. CAS No. 165259-91-6. Molecular formula: C16H25ClN2O. Mole weight: 296.83. | |
| Rac-cis-Sertraline Hydrochloride | . Uses: Potent and selective inhibitors of serotonin uptake. Synonyms: cis racemic Setraline; rac-cis-Sertraline Hydrochloride. CAS No. 79617-95-1. Molecular formula: C17H18Cl3N. | |
| rac-Duloxetine Hydrochloride (1:1 R:S Mixtures) | rac-Duloxetine Hydrochloride (1:1 R:S Mixtures) is the racemate of Duloxetine hydrochloride, which is a serotonin-norepinephrine reuptake inhibitor used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, neuropathic pain and central sensitization. Synonyms: N-Methyl-γ-(1-naphthalenyloxy)-2-thiophenepropanamine Hydrochloride; (RS)-Duloxetine hydrochloride; Duloxetine EP impurity A; N-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propan-1-amine hydrochloride; (±)-Duloxetine hydrochloride; 2-Thiophenepropanamine, N-methyl-γ-(1-naphthalenyloxy)-, hydrochloride (1:1). CAS No. 947316-47-4. Molecular formula: C18H20ClNOS. Mole weight: 333.87. | |
| rac Efavirenz | rac Efavirenz is a mixture of both enantiomers for Efavirenz. Synonyms: 6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one. Grades: > 95%. CAS No. 177530-93-7. Molecular formula: C14H9ClF3NO2. Mole weight: 315.67. | |
| Racemic Fudosteine HCl | Grades: > 95%. Molecular formula: C6H14NO3SCl. Mole weight: 215.70. | |
| Racemic-Linezolid Impurity PNU140155 | Grades: > 95%. Molecular formula: C15H22FN3O3. Mole weight: 311.36. | |
| rac Epinephrine-1-Sulfuronthiate | An impurity of Epinephrine. Epinephrine is an endogenous catcholamine with combined α-and β-agonist activity and its principal sympathomimetic hormone is produced by the adrenal medulla. CAS No. 859066-02-7. Molecular formula: C9H13NO5S2. Mole weight: 279.33. | |
| rac-Epinephrine-3-O-sulfate | A derivative of Epinephrine. Epinephrine is an endogenous catcholamine with combined α-and β-agonist activity and its principal sympathomimetic hormone is produced by the adrenal medulla. Synonyms: (±)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol 2-(Hydrogen sulfate); (±)-Epinephrine-3-O-sulfate; 2-Hydroxy-5-(1-hydroxy-2-(methylamino)ethyl)phenyl Hydrogen Sulfate. Grades: ≥95%. CAS No. 112346-91-5. Molecular formula: C9H13NO6S. Mole weight: 263.27. | |
| rac-Epinephrine 4-Glucuronide (Mixture of Diastereomers) | An impurity of Epinephrine. Epinephrine is an endogenous catcholamine with combined α-and β-agonist activity and its principal sympathomimetic hormone is produced by the adrenal medulla. Molecular formula: C15H21NO9. Mole weight: 359.33. | |
| rac Epinephrine-5-Sulfonate | An impurity of Epinephrine. Epinephrine is an endogenous catcholamine with combined α-and β-agonist activity and its principal sympathomimetic hormone is produced by the adrenal medulla. Molecular formula: C9H13NO6S. Mole weight: 263.27. | |
| rac-Etodolac | rac-Etodolac is a non-selective inhibitor of COX. Uses: Cyclooxygenase 2 inhibitors. Synonyms: Etodolac, AY 24,236, AY 24236, AY-24,236, AY-24236, AY24,236, AY24236, 1,8-Diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic Acid; (RS)-Etodolic Acid; (+/-)-Etodolac; AY 24236; Eccoxolac; Edolan; Etodine; Etodolic Acid; Etogesic; Lodin XL; Lodine; NIH 9918; NSC 282126; Napilac; Ramodar; Tedolan; Ultradol; Zedolac. Grades: > 95%. CAS No. 41340-25-4. Molecular formula: C17H21NO3. Mole weight: 287.35. | |
| rac Fosfomycin Benzylamine Salt | rac Fosfomycin Benzylamine Salt is one of fosfomycin impurities. Fosfomycin is an antibiotic that exerts a broad spectrum of antibacterial activity. It was produced by certain Streptomyces species. CAS No. 27699-10-1. Molecular formula: C10H16NO4P. Mole weight: 245.21. | |
| rac Metanephrine Hydrochloride Salt | A metabolite of Epinephrine. Epinephrine is an endogenous catcholamine with combined α-and β-agonist activity and its principal sympathomimetic hormone is produced by the adrenal medulla. Synonyms: 4-Hydroxy-3-methoxy-α-[(methylamino)methyl]benzenemethanol Hydrochloride; α-[(Methylamino)methyl]-vanillyl Alcohol Hydrochloride; (±)-Metanephrine Hydrochloride; 3-Methoxyadrenaline Hydrochloride; 3-O-Methylepinephrine Hydrochloride; Metadrenaline Hydrochloride. Grades: 95%. CAS No. 881-95-8. Molecular formula: C10H16ClNO3. Mole weight: 233.69. | |
| rac-Metanephrine-O-sulfate | rac-Metanephrine-O-sulfate is a metabolite of Epinephrine, which is a hormone used to treat a number of conditions including allergic reaction anaphylaxis, cardiac arrest, and superficial bleeding. Synonyms: α-[(Methylamino)methyl]-4-(hydrogen sulfate) Vanillyl Alcohol; 3-Methoxy-α-[(methylamino)methyl]-4-(sulfooxy)benzenemethanol; Benzenemethanol, 3-methoxy-α-[(methylamino)methyl]-4-(sulfooxy)-. Grades: ≥95%. CAS No. 7367-47-7. Molecular formula: C10H15NO6S. Mole weight: 277.29. | |
| rac Methyl Efavirenz | Efavirenz potential synthetic impurity and degradation product. Synonyms: 6-Chloro-1,4-dihydro-4-[2-(2-methylcyclopropyl)ethynyl]-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one; 6-Chloro-1,4-dihydro-4-[(2-methylcyclopropyl)ethynyl]-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one. Grades: > 95%. CAS No. 353270-76-5. Molecular formula: C15H11ClF3NO2. Mole weight: 329.7. | |
| rac N-Methyl Atomoxetine Oxalate | rac N-Methyl Atomoxetine Oxalate is a derivative of Atomoxetine, which is a selective norepinephrine (NE) reuptake inhibitor for the treatment of attention-deficit hyperactivity disorder (ADHD). Synonyms: N,N-Dimethyl-γ-(2-methylphenoxy)-benzenepropanamine Ethanedioate (1:1); N,N-Dimethyl-(3-phenyl-3-O-tolyloxy-propyl)-amine oxalate; N,N-Dimethyl-3-(2-methylphenoxy)-3-phenyl-1-propanamine ethanedioate (1:1); Benzenepropanamine, N,N-dimethyl-γ-(2-methylphenoxy)-, ethanedioate (1:1); N,N-dimethyl-3-(o-tolyloxy)-3-phenyl-propylamine oxalate. Grades: ≥95%. CAS No. 107688-86-8. Molecular formula: C20H25NO5. Mole weight: 359.42. | |
| rac N-Methyl Epinephrine Hydrochloride Salt | An analogue of Epinephrine. Epinephrine is an endogenous catcholamine with combined α-and β-agonist activity and its principal sympathomimetic hormone is produced by the adrenal medulla. Synonyms: 3,4-Dihydroxy-α-(dimethylaminomethyl)benzyl Alcohol Hydrochloride Salt; DL-1-(3,4-Dihydroxyphenyl)-2-dimethylaminoethano Hydrochloride Saltl; Methadren Hydrochloride Salt; N-Methyladrenaline Hydrochloride Salt; N-Methylepinephrine Hydrochloride Salt; NSC 169812; dl-N-Methylepinephrine Hydrochloride Salt; α-(3,4-Dihydroxyphenyl)-α-hydroxy-β-dimethylaminoethane Hydrochloride Salt; α-(3,4-Dihydroxyphenyl)-β-dimethylaminoethanol Hydrochloride Salt; α-(Dimethylaminomethyl)protocatechuyl Alcoho Hydrochloride Saltl; 4-[2-(Dimethylamino)-1-hydroxyethyl]-1,2-benzenediol Hydrochloride Salt. CAS No. 62-22-6. Molecular formula: C10H16ClNO3. Mole weight: 233.69. | |
| rac-N'-Nitrosonornicotine 1-N-Oxide | rac-N'-Nitrosonornicotine 1-N-Oxide is a metabolite of N'-Nitrosonornicotine. Synonyms: NNN-N-Oxide; 3-[(2RS)-1-Nitroso-2-pyrrolidinyl]-pyridine-1-oxide; 3-(1-Nitroso-2-pyrrolidinyl)pyridine 1-oxide; Pyridine, 3-(1-nitroso-2-pyrrolidinyl)-, 1-oxide; N'-Nitrosonornicotine-N-oxide; NNN-1-N-oxide. Grades: ≥95%. CAS No. 1314916-69-2. Molecular formula: C9H11N3O2. Mole weight: 193.20. | |
| rac-Normetanephrine-β-O-glucuronide | rac-Normetanephrine-β-O-glucuronide is a metabolite of Epinephrine, which is a hormone and medication used to treat a number of conditions including allergic reaction anaphylaxis, cardiac arrest, and superficial bleeding. Synonyms: 4-(2-Amino-1-hydroxyethyl)-2-methoxyphenyl-β-D-glucopyranosiduronic Acid; Normetanephrine 4-glucuronide; β-D-Glucopyranosiduronic acid, 4-(2-amino-1-hydroxyethyl)-2-methoxyphenyl. Grades: 98%. CAS No. 28932-87-8. Molecular formula: C15H21NO9. Mole weight: 359.33. | |
| rac trans-10,11-Dihydro-10,11-dihydroxy Carbamazepine | Cas No. 58955-93-4. | |
| rac-trans 3'-Aminomethyl Nicotine | . Uses: A nicotine conjugate for therapy of nicotine addiction. Synonyms: (2S,3R)-rel-1-Methyl-2-(3-pyridinyl)-3-pyrrolidinemethanamine; 3-Pyrrolidinemethanamine, 1-methyl-2-(3-pyridinyl)-, (2R,3S)-rel-. Grades: 98%. CAS No. 623579-03-3. Molecular formula: C11H17N3. Mole weight: 191.27. | |
| rac-trans-Ketoconazole | Cas No. 83374-59-8. | |
| Radotinib | Radotinib, also known as IY-5511, is an orally available, hydrochloride salt form of radotinib, a second-generation tyrosine kinase inhibitor of Bcr-Abl fusion protein and the platelet-derived growth factor receptor (PDGFR), with potential antineoplastic activity. Upon administration, radotinib specifically inhibits the Bcr-Abl fusion protein, an abnormal enzyme expressed in Philadelphia chromosome-positive chronic myeloid leukemia (CML) cells. In addition, this agent also inhibits PDGFR thereby blocking PDGFR-mediated signal transduction pathways. The inhibitory effect of radotinib on these specific tyrosine kinases may decrease cellular proliferation and inhibit angiogenesis. This agent has shown potent efficacy in CML cells that are resistant to the first-generation standard tyrosine kinase inhibitors, such as imatinib, nilotinib and dasatinib. PDGFR, upregulated in many tumor cell types, is a receptor tyrosine kinase essential to cell migration and the development of the microvasculature. Check for active clinical trials or closed clinical trials using this agent. Synonyms: IY-5511; IY 5511; IY5511; 4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyrazin-2-ylpyrimidin-2-yl)amino]benzamide. Grades: >98%. CAS No. 926037-48-1. Molecular formula: C27H21F3N8O. Mole weight: 530.515. | |
| RAF-709 | RAF-709 is a novel Raf kinase inhibitor used for the treatment of non-small cell lung cancer (NSCLC). Uses: The treatment of nsclc. Synonyms: N-(2-methyl-5'-morpholino-6'-((tetrahydro-2H-pyran-4-yl)oxy)-[3,3'-bipyridin]-5-yl)-3-(trifluoromethyl)benzamide; RAF709; RAF-709; RAF 709. Grades: 98%. CAS No. 1628838-42-5. Molecular formula: C28H29F3N4O4. Mole weight: 542.56. | |
| Rafigrelide | Rafigrelide is a platelet aggregation inhibitor, which plays a central role in atherothrombotic events. It could prolonge clot formation time and reduce clot strength. Uses: Rafigrelide plays a central role in atherothrombotic events. Synonyms: 6,7-Dichloro-3,3-dimethyl-5,10-dihydroimidazo[2,1-b]quinazolin-2(3H)-one;6,7-Dichloro-3,3-dimethyl-5,10-dihydroimidazo[2,1-b]quinazolin-2-one. Grades: >98 %. CAS No. 1029711-88-3. Molecular formula: C12H11Cl2N3O. Mole weight: 284.14. | |
| (R)-α,α-Diphenylprolinol Hydrochloride | (R)-α,α-Diphenylprolinol Hydrochloride is the (R)-enantiomer of Diphenylprolinol, which is a norepinephrine-dopamine reuptake inhibitor used as a designer drug. Synonyms: (R)-α,α-Diphenyl-2-pyrrolidinemethanol Hydrochloride; (R)-D2PM Hydrochloride; (2R)-α,α-Diphenyl-2-pyrrolidinemethanol Hydrochloride; α,α-Diphenyl-D-prolinol Hydrochloride. Grades: ≥95%. CAS No. 172152-19-1. Molecular formula: C17H20ClNO. Mole weight: 289.80. | |
| (R)-α-Methyltryptamine | (R)-α-Methyltryptamine is an alkaloid isolated from the herbs of Arundo donax L and used as an antidepressant. Synonyms: (-)-(αR)-α-Methyl-1H-indole-3-ethanamine; (-)-α-Methyltryptamine; (R)-(-)-α-Methyltryptamine; (R)-3-(2-Aminopropyl)-1H-indole; (R)-3-(2-Aminopropyl)indole. Grades: 98%. CAS No. 7795-52-0. Molecular formula: C11H14N2. Mole weight: 174.24. | |
| Raltegravir Potassium Salt | Raltegravir is a potent, selective, and orally bioavailable inhibitor of HIV integrase (IC50 = 15 nM). It is metabolized primarily by uridine diphosphate glucuronosyltransferase 1A. Raltegravir has long-term efficacy and safety in managing HIV-1 infection in adults, children, and adolescents. Uses: Anti-hiv agents. Synonyms: MK-0518; MK 0518; MK0518; Raltegravir. Grades: 98%. CAS No. 871038-72-1. Molecular formula: C20H20FKN6O5. Mole weight: 482.514. | |
| Raltitrexed | Raltitrexed is a thymidylate synthase inhibitor with an IC50 of 9 nM for the inhibition of L1210 cell growth. Raltitrexed is used as an antimetabolite drug used in the treatment of colorectal cancer, and may be beneficial for malignant mesothelioma treatment. Uses: The treatment of colorectal cancer. Synonyms: Tomudex; ZD1694; ZD-1694; ICI-D1694; (2S)-2-[[5-[methyl-[(2-methyl-4-oxo-1H-quinazolin-6-yl)methyl]amino]thiophene-2-carbonyl]amino]pentanedioic acid. Grades: > 98%. CAS No. 112887-68-0. Molecular formula: C21H22N4O6S. Mole weight: 458.49. | |
| Ramatroban | Ramatroban is a thromboxane A(2) (TxA(2)) antagonist marketed for allergic rhinitis. Synonyms: Ramatroban; Bay u 3406; Bay u-3405; BAY u3405; EN 137774. Grades: >98%. CAS No. 116649-85-5. Molecular formula: C21H21FN2O4S. Mole weight: 416.47. | |
| Ramosetron Impurity 12 | An impurity of Ramosetron.Ramosetron is a serotonin 5-HT3 receptor antagonist for the treatment of nausea and vomiting. Synonyms: Pyrrolidin-1-yl(4,5,6,7-tetrahydro-1H-benzo[d]imidazol-5-yl)methanone hydrochloride; pyrrolidin-1-yl(4,5,6,7-tetrahydro-3H-benzimidazol-5-yl)methanone; hydrochloride; VIQQUDRWPRGFBZ-UHFFFAOYSA-N; SCHEMBL9051125; DTXSID60597128; FD7376; (4,5,6,7-TETRAHYDRO-1H-BENZO[D]IMIDAZOL-5-YL)(PYRROLIDIN-1-YL)METHANONE HCL; FT-0709212; 5-pyrrolidinocarbonyl-4,5,6,7-tetrahydrobenzimidazole hydrochloride; N-[(4,5,6,7-tetrahydrobenzimidazol-5-yl)carbonyl]pyrrolidine hydrochloride; N-[ (4, 5, 6, 7-tetrahydrobenzimidazol-5-yl) carbonyl]pyrrolidinehydrochloride; Methanone, 1-pyrrolidinyl(4,5,6,7-tetrahydro-1H-benzimidazol-6-yl)-, hydrochloride (1:1); Pyrrolidin-1-yl(4,5,6,7-tetrahydro-1H-benzo[d]imidazol-5-yl)methanonehydrochloride; (Pyrrolidin-1-yl)(4,5,6,7-tetrahydro-1H-benzimidazol-6-yl)methanone--hydrogen chloride (1/1). Grades: > 95%. CAS No. 132036-42-1. Molecular formula: C12H17N3O. Mole weight: 219.29. | |
| Ranitidine Impurity J | An impurity of Ranitidine.Ranitidine is a medication that decreases stomach acid production. It can be used in treatment of peptic ulcer disease. Synonyms: 1, 1'-N-[Methylenebis (sulphanediylethylene)]bis (N'-methyl-2-nitroethene-1, 1-diamine. Grades: > 95%. CAS No. 1331637-48-9. Molecular formula: C11H22N6O4S2. Mole weight: 366.46. | |
| Ranolazine 2,3,4-Tri-O-isobutyryl-β-D-Glucuronide Methyl Ester (mixture of diastereomers) | Ranolazine 2,3,4-Tri-O-isobutyryl-β-D-Glucuronide Methyl Ester (mixture of diastereomers) is a derivative of Ranolazine, which is a medication used to treat heart-related chest pain. Synonyms: methyl (2S,3S,4S,5R,6R)-6-[1-[4-[2-(2,6-dimethylanilino)-2-oxoethyl]piperazin-1-yl]-3-(2-methoxyphenoxy)propan-2-yl]oxy-3,4,5-tris(2-methylpropanoyloxy)oxane-2-carboxylate; 1-(4-{2-[(2,6-Dimethylphenyl)amino]-2-oxoethyl}-1-piperazinyl)-3-(2-methoxyphenoxy)-2-propanyl methyl 2,3,4-tri-O-isobutyryl-β-D-glucopyranosiduronate; 1-Piperazineacetamide, N-(2,6-dimethylphenyl)-4-[3-(2-methoxyphenoxy)-2-[[6-methyl-2,3,4-tris-O-(2-methyl-1-oxopropyl)-β-D-glucopyranuronosyl]oxy]propyl]-. Molecular formula: C43H61N3O13. Mole weight: 827.95. | |
| Ranolazine 4-N-Oxide | Ranolazine 4-N-Oxide is one of Ranolazine metabolites. Ranolazine is an anti-ischemic agent which modulates myocardial metabolism. Synonyms: Ranolazine Impurity 2. Molecular formula: C24H33N3O5. Mole weight: 443.53. | |
| Raubasine | Cas No. 483-04-5. | |
| Raxatrigine | Raxatrigine is a novel analgesic for the treatment of lumbosacral radiculopathy (sciatica) and trigeminal neuralgia. It acts as a selective, small-molecule, state-dependent Nav1.7 voltage-gated sodium channel blocker. It is a peripherally and centrally acting agent that inhibits sodium channels in a state-dependent fashion. It shows selectivity for the Nav1.7 subtype over the other subtypes tested for both the resting and depolarized states. It was developed by Convergence Pharmaceuticals. It received orphan-drug designation from the US Food and Drug Administration in July 2013. It is currently in phase II studies in bipolar depression. Uses: Raxatrigine is a novel analgesic for the treatment of lumbosacral radiculopathy (sciatica) and trigeminal neuralgia. it received orphan-drug designation from the us food and drug administration in july 2013. Synonyms: (2S,5R)-5-(4-((2-fluorobenzyl)oxy)phenyl)pyrrolidine-2-carboxamide; GSK1014802; GSK 1014802; GSK-1014802; CNV1014802; CNV-1014802; CNV 1014802; Raxatrigine. Grades: >98%. CAS No. 934240-30-9. Molecular formula: C18H19FN2O2. Mole weight: 314.35. | |
| RBC8 | RBC8 is a novel small molecule inhibitor of Ral GTPase; has IC50 of 3.5 μM in H2122 cell and 3.4 μM in H358 cell. Synonyms: RBC8; RBC-8; RBC 8. Grades: >98%. CAS No. 361185-42-4. Molecular formula: C25H20N4O3. Mole weight: 424.45. | |
| (R)-Bepotastine | Synonyms: 1-Piperidinebutanoic acid, 4-[(4-chlorophenyl)-2-pyridinylmethoxy]-, (R)-; 1-Piperidinebutanoic acid, 4-[(R)-(4-chlorophenyl)-2-pyridinylmethoxy]-; (R)-Bepotastine. Grades: > 95%. CAS No. 190730-41-7. Molecular formula: C21H25ClN2O3. Mole weight: 388.90. | |
| RC 160 | RC 160 is a cyclic octapeptide somatostatin analog (Ki= 0.7, 5.4, 30.9, 45 and > 1000 nM for sst5, sst2, sst3, sst4 and sst1 receptors respectively). RC 160 is a peptide neurokinin-1 receptor (NK1) antagonist and inhibits increases in vascular permeability stimulated by substance P in a concentration-dependent manner in isolated guinea pig trachea and main bronchi. It is used in the treatment of esophageal variceal bleeding in patients with cirrhotic liver disease and AIDS-related diarrhea. Uses: Antineoplastic agents. Synonyms: D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-L-tryptophanamide, cyclic (2?7)-disulfide; BMY-41606; BMY 41606; BMY41606; RC160; RC 160; RC-160; DP-05-094; Octastatin; Vapreotide acetate. Grades: 98%. CAS No. 103222-11-3. Molecular formula: C57H70N12O9S2. Mole weight: 1131.37. | |
| (R)-cis-5ξ-Methyl Atracurium Dibesylate | Cas No. 1193104-82-3. | |
| (R,cis)-7-Methyl Atracurium dibesylate | (R,cis)-7-Methyl Atracurium dibesylate is an impurity of Cisatracurium, an enantiomer of a neuromuscular blocking agent. Synonyms: (1R,2R,1'R,2'R)-2,2'-{(3-Methyl-1,5-pentanediyl)bis[oxy(3-oxo-3,1-propanediyl)]}bis[1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolinium] dimethanesulfonate; (1R,1'R,2R,2'R)-2,2'-(((3-Methylpentane-1,5-diyl)bis(oxy))bis(3-oxopropane-3,1-diyl))bis(1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium)Dibesylate. CAS No. 1193104-80-1. Molecular formula: C56H80N2O18S2. Mole weight: 1133.37. | |
| (R)-(-)-Clenbuterol | (R)-(-)-Clenbuterol is the (R)-Enantiomer of Clenbuterol and is used as a reagent in the synthesis of pyrazolopyridine derivatives as inhibitors of phosphodiesterase-4(PDE-IV) and production of tumor necrosis factor-α (TNF-α). Uses: (r)-enantiomer of clenbuterol. substituted phenylethanolamine with β2 sympathomimetic activity. bronchodilator. Synonyms: (α R) -4-Amino-3, 5-dichloro-α -[[ (1, 1-dimethylethyl) amino]methyl]benzenemethanol; (-)-Clenbuterol; (R)-Clenbuterol. Grades: 98%. CAS No. 50306-03-1. Molecular formula: C12H18Cl2N2O. Mole weight: 277.19. | |
| (R)-Dapoxetine Hydrochloride | (R)-Dapoxetine Hydrochloride is a selective serotonin reuptake inhibitor (SSRI). Synonyms: (αR)-N,N-Dimethyl-α-[2-(1-naphthalenyloxy)ethyl]-benzenemethanamine Hydrochloride. Grades: > 95%. CAS No. 156453-51-9. Molecular formula: C21H24ClNO. Mole weight: 341.87. | |
| (R)-Desmethyl Atomoxetine Hydrochloride | (R)-Desmethyl Atomoxetine Hydrochloride is a metabolite of Atomoxetine, which is a selective norepinephrine (NE) reuptake inhibitor for the treatment of attention-deficit hyperactivity disorder (ADHD). Synonyms: (R)-γ-(2-Methylphenoxy)benzenepropanamine Hydrochloride; Atomoxetine N-Desmethyl Impurity; (R)-3-(2-Methylphenoxy)-3-phenyl-1-propanamine hydrochloride (1:1); Benzenepropanamine, γ-(2-methylphenoxy)-, (3R)-, hydrochloride (1:1). Molecular formula: C16H20ClNO. Mole weight: 277.79. | |
| (R)-Desmethyl Doxylamine | Desmethyl Doxylamine is an impurity of Doxylamine. Synonyms: N,N-Dimethyl-2-(phenyl-2-pyridinylmethoxy)ethanamine; 2-[α -[2- (Dimethylamino) ethoxy]benzyl]pyridine. Grades: > 95%. CAS No. 1221-70-1. Molecular formula: C16H20N2O. Mole weight: 256.34. | |
| R-Doxazosin | (R)-Doxazosin is an Isomer of Doxazosin Mesylate. Synonyms: (R)-1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl]-piperazine. Grades: > 95%. CAS No. 70918-17-1. Molecular formula: C23H25N5O5. Mole weight: 451.49. | |
| R-Doxylamine | R-isomer of Doxylamine. Synonyms: N,N-Dimethyl-2-[(1R)-1-phenyl-1-(2-pyridinyl)ethoxy]ethanamine; (R)-N,N-Dimethyl-2-(1-phenyl-1-(pyridin-2-yl)ethoxy)ethanamine. Grades: > 95%. CAS No. 1391849-33-4. Molecular formula: C17H22N2O. Mole weight: 270.37. | |
| (R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoic acid | (R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoic acid is an impurity of Sacubitril, an endopeptidase inhibitor that is effective in the treatment of hypertension and heart failure. Synonyms: (2E,4R)-5-[1,1'-biphenyl]-4-yl-4-[[(1,1-dimethylethoxy)carbonyl]amino]-2-methyl-2-Pentenoicacid; 5-Biphenyl-4-yl-4-tert-butoxycarbonylamino-2-methyl-pent-2-enoicacid; 2-Pentenoicacid, 5-[1, 1'-biphenyl]-4-yl-4-[[ (1, 1-dimethylethoxy) carbonyl]aminChemicalbooko]-2-methyl-, (2E,4R)-; (R)-5-biphenyl-4-yl-4-tert-butoxycarbonylamino-2-methyl-pent-(E)-2-enoic acid; SCHEMBL18765. Grades: 95%. CAS No. 1012341-48-8. Molecular formula: C23H27NO4. Mole weight: 381.46. | |
| Rebamipide impurity 2 | An impurity of Rebamipide. Rebamipide is an amino acid derivative of 2-(1H)-quinolinone. It can be used for mucosal protection, healing of gastroduodenal ulcers, and treatment of gastritis. Grades: > 95%. CAS No. 94670-39-0. Molecular formula: C8H6ClNO2. Mole weight: 183.59. | |
| Rebastinib | Rebastinib is an orally bioactive inhibitor of Bcr-Abl that binds to and inhibits Bcr-Abl fusion oncoprotein. Rebastinib changes the conformation of the folded protein to disallow ligand-dependent and ligand-independent activation. It also exhibits inhibitory activity at SRC, LYN, FGR, HCK, KDR, FLT3, and Tie-2. Uses: Antineoplastic agents. Synonyms: DCC2036; DCC-2036; DCC 2036; Rebastinib. 4-[4-[(5-tert-butyl-2-quinolin-6-ylpyrazol-3-yl)carbamoylamino]-3-fluorophenoxy]-N-methylpyridine-2-carboxamide. Grades: ≥98%. CAS No. 1020172-07-9. Molecular formula: C30H28FN7O3. Mole weight: 553.598. | |
| Reboxetine Mesylate | Reboxetine is a norepinephrine reuptake inhibitor with Ki of 8.2 nM. Synonyms: PNU 155950E. Grades: >98%. CAS No. 98769-84-7. Molecular formula: C19H23NO3·CH4O3S. Mole weight: 409.5. | |
| Reduced Haloperidol | Reduced Haloperidol has shown potent inhibition of CYP2D6. Synonyms: (±)-4-(4-chlorophenyl)-α-(4-fluorophenyl)-4-hydroxy-1-piperidinebutanol; 4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol; 1-Piperidinebutanol, 4-(4-chlorophenyl)-.alpha.-(4-fluorophenyl)-4-hydroxy-(R/S); Aids-001752; Hydroxy-halope. Grades: > 95%. CAS No. 34104-67-1. Molecular formula: C21H25ClFNO2. Mole weight: 377.89. | |
| Reduced Omega-1-Hydroxy Eperisone | A metabolite of Eperisone. Eperisone relaxes both skeletal muscles and vascular smooth muscles. Synonyms: 1-(4-(1-hydroxyethyl)phenyl)-2-methyl-3-(piperidin-1-yl)propan-1-ol. Grades: > 95%. Molecular formula: C17H27NO2. Mole weight: 277.41. | |
| Reduced Omega-Hydroxy Eperisone | |
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