BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
Hexanoyl coenzyme A trilithium salt. Synonyms: Caproyl Coenzyme A trilithium salt. Grade: 95%. CAS No. 103476-19-3. Molecular formula: C27H43Li3N7O17P3S. Mole weight: 883.6.
Hexanoyl Docetaxel Metabolite M4
Hexanoyl Docetaxel Metabolite M4 is a metabolite of Docetaxel, which is a semisynthetic derivative of Paclitaxel used to treat a variety of cancers, including breast, head and neck, stomach, prostate, and non-small cell lung cancer. Synonyms: 3-Oxazolidinepropanoic acid, 5,5-dimethyl-2,4-dioxo-α-[(1-oxohexyl)oxy]-β-phenyl-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-; (2α,5β,7β,10β,13α)-4-Acetoxy-13-{[(2R,3S)-3-(5,5-dimethyl-2,4-dioxo-1,3-oxazolidin-3-yl)-2-(hexanoyloxy)-3-phenylpropanoyl]oxy}-1,7,10-trihydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate. Molecular formula: C49H59NO16. Mole weight: 917.99.
Hexanoyl Docetaxel Metabolites M1 and M3 (Mixture of Diastereomers)
Hexanoyl Docetaxel Metabolites M1 and M3 (Mixture of Diastereomers) are metabolites of Docetaxel, which is a semisynthetic derivative of Paclitaxel used to treat a variety of cancers, including breast, head and neck, stomach, prostate, and non-small cell lung cancer. Synonyms: 3-Oxazolidinepropanoic acid, 4-hydroxy-5,5-dimethyl-2-oxo-α-[(1-oxohexyl)oxy]-β-phenyl-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-; (2α,5β,7β,10β,13α)-4-Acetoxy-13-{[(2R,3S)-2-(hexanoyloxy)-3-(4-hydroxy-5,5-dimethyl-2-oxo-1,3-oxazolidin-3-yl)-3-phenylpropanoyl]oxy}-1,7,10-trihydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate. Molecular formula: C49H61NO16. Mole weight: 920.00.
Hexanoyl-L-carnitine chloride
Hexanoyl-L-carnitine chloride is a derivative of L-carnitine. L-carnitine is an amino acid derivative that reduces accumulation of metabolic wastes, and is currently used as a weight-loss agent. Synonyms: Caproyl-L-Carnitine; C6 Carnitine; L-Hexanoylcarnitine. Grade: ≥95%. CAS No. 162067-53-0. Molecular formula: C13H26NO4·Cl. Mole weight: 295.80.
Hexanoyl-L-homoserine lactone
An active quorum sensing modulator first recognised in rhizobium leguminosarum. It is produced by the strain of Nitrosomonas europeae. Synonyms: C6-HSL; N-Hexanoyl-L-homoserine lactone; N-[(3S)-2-Oxotetrahydrofuran-3-Yl]hexanamide; (S)-N-(2-Oxotetrahydrofuran-3-yl)hexanamide; HHL. Grade: >99% by HPLC. CAS No. 147852-83-3. Molecular formula: C10H17NO3. Mole weight: 199.25.
Hexa-O-acetylmaltal
Hexa-O-acetylmaltal, an extensively researched biomedicine, emerges as an indispensable remedy for targeted intervention against malignant and autoimmune afflictions. Through precise enzymatic modulation, this potent therapeutic marvel thwarts the proliferation and migration of cancerous cells, instilling rays of hope for stricken patients grappling with these formidable tribulations. Synonyms: 1,5-Anhydro-2-deoxy-4-O-(2,3,4,6-tetra-O-acetyl-a-D-glucopyranosyl)-D-arabino-hex-1-enitol diacetate; Maltal peracetate; D-arabino-Hex-1-enitol, 1,5-anhydro-2-deoxy-4-O-(2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl)-, diacetate; Hexaacetyl-D-maltal; D-arabino-Hex-1-enitol, 1,5-anhydro-2-deoxy-4-O-(2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl)-, 3,6-diacetate. CAS No. 67314-34-5. Molecular formula: C24H32O15. Mole weight: 560.50.
Hexa-O-benzoyl 10-Demethyl Colchicoside
Hexa-O-benzoyl 10-Demethyl Colchicoside is an intermediate in synthesizing Isothiocolcicoside, which is an impurity of Thiocolchicoside, a GABA receptor antagonist which is prescribed as a muscle relaxant having analgesic effects. Synonyms: (2S,3R,4S,5R,6R)-2-(((S)-10-(Benzoyloxy)-1,2-dimethoxy-9-oxo-7-(3-oxo-3-phenylpropanamido)-5,6,7,9-tetrahydrobenzo[a]heptalen-3-yl)oxy)-6-((benzoyloxy)methyl)tetrahydro-2H-pyran-3,4,5-triyl Tribenzoate. Molecular formula: C68H55NO17. Mole weight: 1158.16.
Hexapeptide-9 is a novel small molecule synthetic six-membered polypeptide consisting of two Gly-Pro-Glin sequences with the same sequence as human collagen IV and XVII. Hexapeptide-9 is an anti-aging that triggers the skin into regeneration of its damaged cells. Synonyms: Glycyl-L-prolyl-L-glutaminylglycyl-L-prolyl-L-glutamine; Collaxyl; Hexapeptide 9; L-Glutamine, glycyl-L-prolyl-L-glutaminylglycyl-L-prolyl-. Grade: 98%. CAS No. 885024-94-2. Molecular formula: C24H38N8O9. Mole weight: 582.61.
Hexasaccharide dp6
Hexasaccharide dp6 is a biomedical product used for studying blood-related disorders and enhancing immune response. Derived from various natural sources, it exhibits potential anticoagulant and immunostimulatory properties. Molecular formula: C36H45N3O57S9(NH4)12. Mole weight: 1936.78.
Hexasodium phytate
Hexasodium Fytate is an inositol phosphate and hydroxyapatite formation inhibitor with antioxidant and anticancer activities. Synonyms: hexasodium myo-inositol hexakis(hydrogen phosphate); hexasodium (1R,2r,3S,4R,5s,6S)-cyclohexane-1,2,3,4,5,6-hexayl hexakis(hydrogen phosphate); myo-Inositol-1,2,3,4,5,6-hexaphosphate (sodium salt); myo-inositol, 1,2,3,4,5,6-hexakis(dihydrogen phosphate), sodium salt (1:6); Hexasodium Fytate; SNF 472; Inositol, hexakis(dihydrogen phosphate) hexasodium salt, myo-; myo-inositol, hexakis(dihydrogen phosphate) hexasodium salt. Grade: ≥98%. CAS No. 34367-89-0. Molecular formula: C6H12Na6O24P6. Mole weight: 791.93.
Hexatrimethylsilyl D-Lactose-6'-[1-((4-chlorophenyl)(phenyl)methyl)-4-(2-methoxyethyl)piperazine] Ester is an intermediate in synthesizing Cetirizine 6,6'-O-Lactose Ester Dihydrochloride (6,6'-Mixture), a lactose adduct of Cetirizine. Synonyms: ((2R,3S,4S,5R,6S)-3,4,5-Tris((trimethylsilyl)oxy)-6-(((2R,3R,4S,5R,6S)-4,5,6-tris((trimethylsilyl)oxy)-2-(((trimethylsilyl)oxy)methyl)tetrahydro-2H-pyran-3-yl)oxy)tetrahydro-2H-pyran-2-yl)methyl 2-(2-(4-((4-Chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)acetate. Molecular formula: C54H101ClN2O13Si7. Mole weight: 1218.44.
Hexestrol
Hexestrol is a nonsteroidal synthetic estrogen, with Kis of 0.06 and 0.06 nM, and EC50s of 0.07 and 0.175 nM for ERα and ERβ, respectively. It can be used to study diseases caused by estrogen deficiency and to increase the weight of cattle. Uses: Antineoplastic agents, hormonal; estrogens, non-steroidal. Synonyms: rel-4,4'-[(1R,2S)-1,2-Diethyl-1,2-ethanediyl]bisphenol; meso-3,4-Di(p-hydroxyphenyl)-n-hexane; Cycloestrol; Erythrohexestrol; Estrifar; Hexron; Hormoestrol; Mesohexestrol; NSC 9894; Sinestrol; Synestrol; Synoestrol; Synthovo; Syntrogene; Estronal; meso-Hexestrol. Grade: >98%. CAS No. 84-16-2. Molecular formula: C18H22O2. Mole weight: 270.37.
Hexetidine
Hexetidine, mixture of stereoisomers, is an antibacterial and antifungal agent that destroy fungi by suppressing their ability to grow or reproduce. Synonyms: 1,3-bis(2-Ethylhexyl)-5-methylhexahydro-5-pyrimidinamine; NSC 17764; 5-Amino-1,3-bis(2-ethylhexyl)hexahydro-5-methylpyrimidine; 1,3-Bis(2-ethylhexyl)hexahydro-5-methyl-5-pyrimidinamine; 1,3-Bis(β-ethylhexyl)-5-methyl-5-aminohexahydropyrimidine; 5-Amino-1,3-bis(2-ethylhexyl)-5-methylhexahydropyrimidine; 5-Amino-1,3-bis(β-ethylhexyl)-5-methylhexahydropyrimidine; 5-Amino-1,3-di(β-ethylhexyl)hexahydro-5-methylpyrimidine; Elsix; Glypesin; Hexigel; Hexocil; Hexopyrimidine; Hexoral; Hextril; Oraldene; Sterilate; Sterisil; Triocil; Triscol. Grade: 95%. CAS No. 141-94-6. Molecular formula: C21H45N3. Mole weight: 339.60.
Hexitol
Hexitol is a biomedical product used in the research of various diseases and conditions. It is commonly employed as a pharmaceutical excipient due to its ability to enhance drug solubility and stability. Additionally, Hexitol plays a critical role as a cryoprotectant for cell preservation, making it valuable for biobanking and regenerative medicine. Synonyms: Dulcite; D(-)Mannitol. CAS No. 45007-61-2. Molecular formula: C6H14O6. Mole weight: 182.17.
Hexoprenaline
Hexoprenaline is a selective β2 adrenergic receptor agonist used in the treatment of asthma. It is also used in some countries as a tocolytic agent and a vasoactive agent. Uses: Bronchodilator agents. Synonyms: 4,4'-[1,6-Hexanediylbis[imino(1-hydroxy-2,1-ethanediyl)]]bis-1,2-benzenediol; α,α'-[hexamethylenebis(iminomethylene)]bis[3,4-dihydroxybenzyl Alcohol; Broncholysin; Byk 1512; Ipradol; N,N'-Bis[2-(3,4-dihydroxyphenyl)-2-hydroxyethyl]hexamethylenediamine; ST 1512. Grade: > 95%. CAS No. 3215-70-1. Molecular formula: C22H32N2O6. Mole weight: 420.51.
Hexoprenaline Sulphate is a pharmaceutical product used in the biomedical industry for the research of asthma and chronic obstructive pulmonary disease (COPD). It acts as a bronchodilator and beta-adrenergic agonist, relaxing the muscles in the airways to improve breathing. Uses: Bronchodilator agents. Synonyms: 1,2-benzenediol,4,4'-(1,6-hexanediylbis(imino(1-hydroxy-2,1-ethanediyl)))bis; 2,2'-(hexamethylenediimino)-1,1'-bis(3,4-dihydroxyphenyl)diethanolsulfate; benzylalcohol,alpha,alpha'-(hexamethylenebis(iminomethylene))bis(3,4-dihydrox; bronocholysinsulfate; Iprad. Grade: > 95%. CAS No. 32266-10-7. Molecular formula: C22H34N2O10S. Mole weight: 518.59.
Hexyl 2-acetamido-2-deoxy-b-D-glucopyranoside
Hexyl 2-acetamido-2-deoxy-b-D-glucopyranoside is a vital component in the biomedical industry. This product is used as a sugar mimic to study the cellular uptake and metabolism of glucose and to understand its role in various diseases, including diabetes, cancer, and metabolic disorders. Synonyms: Hexyl 2-(acetylamino)-2-deoxy-β-D-glucopyranoside; N-((2R,3R,4R,5S,6R)-2-(hexyloxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)acetamide. CAS No. 190912-49-3. Molecular formula: C14H27NO6. Mole weight: 305.37.
Hexyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranoside, a compound extensively employed in the realm of biomedical science, plays a pivotal role as a fundamental constituent for the synthesis and exploration of pharmaceutical agents targeting a diverse range of ailments, encompassing cancer, inflammation, and infectious diseases. Synonyms: β-D-Glucopyranoside, hexyl 2-(acetylamino)-2-deoxy-, 3,4,6-triacetate; Hexyl-2-(acetylamino)-2-deoxy-3,4,6-triacetate β-D-Glucopyranoside; (2R,3S,4R,5R,6R)-5-Acetamido-2-(acetoxymethyl)-6-(hexyloxy)tetrahydro-2H-pyran-3,4-diyl diacetate. CAS No. 172945-26-5. Molecular formula: C20H33NO9. Mole weight: 431.48.
Hexyl b-D-glucopyranoside
Hexyl b-D-glucopyranoside is a powerful compound widely used in biomedicine. It is a non-ionic detergent often used in membrane protein studies. This product is known for its ability to solubilize and stabilize membrane proteins, making it a key ingredient in protein purification. It is also commonly utilized in drug delivery research, specifically for enhancing the solubility and bioavailability of certain drugs. Synonyms: Hexyl glucoside; Hexyl β-D-glucopyranoside; 1-Hexyl β-D-glucoside; APG 06; n-Hexyl β-D-glucopyranoside; n-Hexyl-β-D-glucoside; Sucraph AG 6206; Triton CG 6. CAS No. 59080-45-4. Molecular formula: C12H24O6. Mole weight: 264.32.
Hexyl b-D-maltopyranoside
Hexyl b-D-maltopyranoside, a pivotal compound within the realm of biomedicine, is extensively employed in the domains of drug formulation and experimental investigations. It demonstrates extraordinary potential in augmenting the solubility and durability of myriad pharmaceutical agents. Furthermore, its application extends to the therapeutic interventions of specific maladies, including cancer and neurological disorders. Synonyms: n-Hexyl b-D-maltoside; Hexyl 4-O-a-D-glucopyranosyl-b-D-glucopyranoside; Hexyl 4-O-α-D-glucopyranosyl-β-D-glucopyranoside; Hexyl β-D-maltoside; n-Hexyl β-D-maltopyranoside. CAS No. 870287-95-9. Molecular formula: C18H34O11. Mole weight: 426.46.
Hexyl b-D-thioglucopyranoside
Hexyl b-D-thioglucopyranoside is a vital biochemical reagent widely used in biomedicine. It acts as a non-ionic detergent and can aid in protein extraction and solubilization. Additionally, it is employed in various drug research and development processes, particularly for studying drug-target interactions and membrane protein crystallization. Synonyms: Hexyl 1-thio-β-D-glucopyranoside; Hexyl β-D-thioglucopyranoside; (2S,3R,4S,5S,6R)-2-(Hexylthio)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol. CAS No. 85618-19-5. Molecular formula: C12H24O5S. Mole weight: 280.38.
hexyl D-glucoside
Hexyl D-glucoside is an extensively employed solubilization compound and detergent in drug formulations and research. Its proficiency in augmenting the solubility of hydrophobic drug entities renders it a quintessential constituent within diverse pharmaceutical arenas. Synonyms: hexyl D-glucoside; Hexyl-D-glucoside. CAS No. 54549-24-5. Molecular formula: C12H24O6. Mole weight: 264.31.
HexylHIBO
HexylHIBO is a Group I mGlu receptor antagonist (Ki = 140 and 110 μM at mGlu1a and mGlu5a receptors, respectively). HexylHIBO was shown to decrease sEPSCs in rat pyramidal neurons in vitro. Synonyms: α-Amino-4-hexyl-2,3-dihydro-3-oxo-5-isoxazolepropanoic acid; Hexylhomoibotenic acid. Grade: ≥98% by HPLC. CAS No. 334887-43-3. Molecular formula: C12H20N2O4. Mole weight: 256.3.
An impurity of Dabigatran. Dabigatran is a very potent anticoagulant, showing that the terminal phenyl can be substituted by the more hydrophilic 2-pyridyl group without substantial loss of activity. Synonyms: Des-(ethyl 3-(N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate Dabigatran Etexilate; Dabigatran Impurity 25. Grade: ≥95%. CAS No. 255706-13-9. Molecular formula: C14H21N3O2. Mole weight: 263.34.
HFI 142
HFI 142 is an insulin-regulated aminopeptidase (IRAP) inhibitor (Ki = 2.01 μM). HFI 142 improves memory in control and memory-deficient mice models. Synonyms: HFI-142; HFI 142; HFI142; Ethyl 2-amino-7-hydroxy-4-(3-pyridinyl)-4H-1-benzopyran-3-carboxylate; 2-Amino-7-hydroxy-4-pyridin-3-yl-4H-chromene-3-carboxylic acid ethyl ester. Grade: ≥98% by HPLC. CAS No. 332164-34-8. Molecular formula: C17H16N2O4. Mole weight: 312.32.
HG-10-102-01
HG-10-102-01 is a potent and selective inhibitor of wild-type LRRK2(IC50=23.3 nM) and the G2019S mutant(IC50=3.2 nM) IC50 Value: 23.3 nM (WT LRRK2); 3.2 nM (LRRK2 G2019S) [1] Target: LRRK2 HG-. Synonyms: HG-10-102-01; HG 10-102-01; HG10-102-01; HG-1010201; HG 1010201; HG1010201; LRRK2 inhibitor 1. Grade: >98%. CAS No. 1351758-81-0. Molecular formula: C17H20ClN5O3. Mole weight: 377.83.
HG122
HG122 promotes androgen receptor degradation through the proteasome pathway inhibiting the castration-resistant prostate cancer. CAS No. 1854976-77-4. Molecular formula: C15H13N5O5. Mole weight: 343.29.
HG-14-10-04
HG-14-10-04 is a potent and specific ALK inhibitor with IC50 of 20 nM. Synonyms: HG-14-10-04. Grade: >98%. CAS No. 1356962-34-9. Molecular formula: C29H34ClN7O. Mole weight: 532.08.
HG6-64-1
HG6-64-1 is a potent and selective B-Raf and mutant B-Raf inhibitor; more information can be found in Patent WO 2011090738. Synonyms: HG-6-64-1; HG 6 64 1; HG6641. Grade: >98%. CAS No. 1315329-43-1. Molecular formula: C32H34F3N5O2. Mole weight: 577.64.
HhAntag is a small molecule inhibitor of GLI1-mediated transcription, an essential down-stream element of the Hedgehog (Hh) pathway. Synonyms: HhAntag; Hh-Antag; Hh Antag; Benzamide, N-[4-chloro-3-[6-(dimethylamino)-1H-benzimidazol-2-yl]phenyl]-3,5-dimethoxy-. Grade: >98%. CAS No. 496794-70-8. Molecular formula: C24H23ClN4O3. Mole weight: 450.92.
Hidrosmin
Hidrosmin is a biomedical product used in the research of chronic venous insufficiency. Synonyms: 4H-1-Benzopyran-4-one, 7-[[6-O-(6-deoxy-α-L-mannopyranosyl)?-β-D-glucopyranosyl]?oxy]?-5-(2-hydroxyethoxy)?-2-[3-(2-hydroxyethoxy)?-4-methoxyphenyl]?-, mixt. with 7-[[6-O-(6-deoxy-α-L-mannopyranosyl)?-β-D-glucopyranosyl]?oxy]?-5-(2-hydroxyethoxy)?-2-(3-hydroxy-4-methoxyphenyl)?-4H-1-benzopyran-4-one and 7-[[6-O-(6-deoxy-α-L-mannopyranosyl)?-β-D-glucopyranosyl]?oxy]?-5-hydroxy-2-[3-(2-hydroxyethoxy)?-4-methoxyphenyl]?-4H-1-benzopyran-4-one Mixture. CAS No. 218433-35-3. Molecular formula: C32H40O17.C30H36O16.C30H36O16.
Hidrosmin-d4
Hidiosmin-d4, is the labelled analogue of Hidiosmin, a derivative of Diosmin, which is a semisynthetic drug and a member of the flavonoid family. It is used for the treatment of venous diseases. Synonyms: 7-[[6-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-(2-hydroxyethoxy)-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one-d4; 5-O-(β-Hydroxyethyl)diosmin-d4. Molecular formula: C30H32D4O16. Mole weight: 656.62.
HIF-2a Translation Inhibitor 76
A cell-permeable HIF-2a translation inhibitor (IC50 value 5 μM). It inhibits HIF-2a translation via enhancing the binding of IRP1 (Iron-Regulatory Protein 1) to the IRE (Iron-Responsive Element) region at the 5' UTR of the HIF-2α mRNA. Synonyms: HIF-2a translation inhibitor; HIF-2|A-IN-4; 882268-69-1; methyl 3-[(2E)-2-[cyano(methylsulfonyl)methylidene]hydrazinyl]thiophene-2-carboxylate; HIF-2alpha-IN-4; SCHEMBL781448; HMS554D20; Methyl 3-(([cyano(methanesulfonyl)methylidene]amino)amino)thiophene-2-carboxylate; CCG-45847; MS-24103; HY-136748; CS-0133535; SR-01000635592-1; methyl 3-(2-(cyano(methylsulfonyl)methylene)hydrazineyl)thiophene-2-carboxylate. Grade: 99%. CAS No. 882268-69-1. Molecular formula: C9H9N3O4S2. Mole weight: 287.32.
HIF Phd Inhibitor 4
An inhibitor of the Hypoxia Inducible Factor (HIF) Prolyl-Hydroxylases (PHD). Synonyms: N-(4-Chlorobenzyl)-3-(5,6-dimethoxy-2-pyridinyl)-2,4-dioxo-1. Grade: 98%. CAS No. 1227946-51-1. Molecular formula: C21H17ClN4O5S. Mole weight: 472.9.
Hikizimycin
Hikizimycin is a potent anthelmintic and antibacterial natural product. Synonyms: Anthelmycin; NSC-337588. Grade: 95%. CAS No. 12706-94-4. Molecular formula: C21H37N5O14. Mole weight: 583.54.
H-Ile-Pro-Pro-OH acetate
H-Ile-Pro-Pro-OH acetate, a milk-derived peptide, inhibits angiotensin-converting enzyme (ACE) with an IC50 of 5 μM. Synonyms: IPP acetate. Molecular formula: C18H31N3O6. Mole weight: 385.46.
HIOC
HIOC is a selective tropomyosin-related kinase receptor B (TrkB) receptor agonist with neuroprotective property. HIOC was shown to prevent retinas from light-induced retinal degeneration (LIRD) in vivo. HIOC is used in the treatment of early brain injury following subarachnoid hemorrhage (SAH). Synonyms: N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]-2-oxo-3-piperidinecarboxamide. Grade: ≥98% by HPLC. CAS No. 314054-36-9. Molecular formula: C16H19N3O3. Mole weight: 301.34.
Hirudin
Extractives and their physically modified derivatives such as proteins, carbohydrates, lipids, nucleic acids, inorganic ions, etc. obtained from Hirudo medicinalis. Uses: Antithrombins. Synonyms: Exhirud; Exhirudine; Hirudex. Grade: 98%. CAS No. 8001-27-2. Molecular formula: C287H440N80O113S7. Mole weight: 7044.
His(2)-AVP
His(2)-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: His(2)-Vasopressin; H-Cys-His-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); L-cysteinyl-L-histidyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-disulfide. Molecular formula: C46H65N15O12S2. Mole weight: 1058.21.
Hispidol
Hispidol ((Z)-Hispidol) inhibits TNF-α induced adhesion of monocytes to colon epithelial cells (IC50= 0.50 μM) and is a potential therapeutic for inflammatory bowel disease. Synonyms: (2Z)-6-hydroxy-2-[(4-hydroxyphenyl)methylidene]-1-benzofuran-3-one; Hispidol; (Z)-4',6-Dihydroxyaurone; AC1NQYA9; 6,4' -dihydroxy aurone. CAS No. 5786-54-9. Molecular formula: C15H10O4. Mole weight: 254.24.
Histamine
Histamine is an organic nitrogenous compound produced by basophils and by mast cells found in nearby connective tissues. Uses: An organic nitrogenous compound. Synonyms: 1h-imidazole-4-ethanamine; 2-(4-IMIDAZOLYL)ETHYLAMINE; 2-(1H-IMIDAZOL-4-YL)-ETHYLAMINE; 4-(2-Aminoethyl)-1H-imidazole; HISTAMINE BASE; HISTAMIN. Grade: ≥97%. CAS No. 51-45-6. Molecular formula: C5H9N3. Mole weight: 111.15.
Histamine dihydrochloride
Histamine dihydrochloride is a histamine salt used to prevent relapse in patients with acute myeloid leukemia (AML). It is also used as an active ingredient in topical analgesia for temporary relief of minor aches and pains of muscles and joints associated with arthritis, simple backache, bruises, sprains and strains. Uses: Present in most mammalian tissues; primarily stored in mast cells and basophils. exhibits multiple biological effects through at least 3 specific receptors. induces bronchoconstriction and vasodilation; stimulates gastric acid secretion; and acts as a neurotransmitter. histamine has been identified as a bedbug pheromone. Synonyms: 1H-Imidazole-4-ethanamine Dihydrochloride; 2-(1H-Imidazol-4-yl)ethanamine Dihydrochloride; 2-(1H-Imidazol-4-yl)ethylamine Dihydrochloride; 4-(2-Aminoethyl)imidazole Dihydrochloride; Ceplene; Peremin; 2-(1H-imidazol-4-yl)ethan-1-amine dihydrochloride. Grade: >98%. CAS No. 56-92-8. Molecular formula: C5H9N3.2HCl. Mole weight: 184.07.
Histamine H4 receptor antagonist-1
Histamine H4 receptor antagonist-1 is an antagonist of histamine H4 receptor. (Extracted from patent WO2010108059A1, compound 60). Synonyms: 2(1H)-Isoquinolinecarboxamide, 7-[2-amino-6-(4-methyl-1-piperazinyl)-4-pyrimidinyl]-N-[(1S)-2-(dimethylamino)-2-oxo-1-(phenylmethyl)ethyl]-3,4-dihydro-. CAS No. 1246207-84-0. Molecular formula: C30H38N8O2. Mole weight: 542.68.
Histamine Phosphate
Histamine phosphate is a potent histamine receptor agonist and vasodilator. It acts directly on the blood vessels to dilate arteries and capillaries mediated by both H1- and H2-receptors. Synonyms: Histamine diphosphate; Histamine acid phosphate; Histamine biphosphate; 2-(1H-imidazol-4-yl)ethanamine bis(phosphate); 1H-Imidazole-4-ethanamine, phosphate (1:2); Histamine dihydrogen phosphate; 4-(2-Aminoethyl)imidazole bis(dihydrogen phosphate); 4-(2-Aminoethyl)imidazole di-acid phosphate; 2-(1H-Imidazol-4-yl)ethanamine phosphate (1:2). Grade: ≥98%. CAS No. 51-74-1. Molecular formula: C5H9N.2H3O4P. Mole weight: 307.14.
HI TOPK 032
HI TOPK 032 is a novel TOPK inhibitor as a T-LAK-cell-originated protein kinase (TOPK) inhibitor, blocking phosphorylation of the substrate histone H2AX with an IC50 value of ~2 μM and providing complete inhibition at 5 μM. Uses: A novel topk inhibitor. Synonyms: HI-TOPK-032; HI-TOPK032; HI-TOPK 032. N-(12-Cyanoindolizino[2,3-b]quinoxalin-2-yl)-2-thiophenecarboxamide. Grade: ≥98%. CAS No. 487020-03-1. Molecular formula: C20H11N5OS. Mole weight: 369.4.
HIV-1 inhibitor-10
HIV-1 inhibitor-10 is a nanomolar HIV-1 maturation inhibitor. Synonyms: 2-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-carboxy-1-isopropenyl-5a,5b,8,8,11a-pentamethyl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]spiro[3.3]hept-2-ene-6,6-dicarboxylic acid; 6-[28-Hydroxy-28-oxolupa-2,20(29)-dien-3-yl]spiro[3.3]hept-5-ene-2,2-dicarboxylic acid. Grade: ≥98% (HPLC). CAS No. 1449660-81-4. Molecular formula: C39H54O6. Mole weight: 618.84.
HIV-1 inhibitor-3
HIV-1 inhibitor-3 is an inhibitor of HIV infection. (Extracted from patent US2018360927). Synonyms: 1-((2R,3R,4S,5S)-3,5-Difluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 1-(2-Deoxy-2,4-difluoro-beta-D-ribofuranosyl)uracil; Uridine, 2'-deoxy-2'-fluoro-4'-C-fluoro-. Grade: ≥95%. CAS No. 1612841-22-1. Molecular formula: C9H10F2N2O5. Mole weight: 264.18.
HIV-1 inhibitor-60
GSK2838232 is a novel human immune virus (HIV) maturation inhibitor being developed for the treatment of chronic HIV infection. GSK2838232 is a betulin derivative. Synonyms: 1443461-21-9; HIV-1 inhibitor-60; HIV Inhibitor GSK2838232; SCHEMBL15038672; EX-A202; HIV Inhibitor GSK2838232?; BDBM271422; BCP07297; US10064873, Example 45; GSK 2838232; AC-33624; HY-108255; CS-0027803; A926344; 4- (((3aR,5aR,5bR,7aR, 9S,11aR,11bR,13aS)- 3a-((R)-2-((3- Chlorobenzyl)(2- (dimethylamino)ethyl) amino)-1-hydroxyethyl)- 1-isopropyl- 5a,5b,8,8,11a- pentamethyl-2-oxo- 3,3a,4,5,5a,5b,6,7. Grade: 98%. CAS No. 1443461-21-9. Molecular formula: C48H73ClN2O6. Mole weight: 809.56.
HIV-1 inhibitor-8
HIV-1 inhibitor-8 is a potent, low-toxic and orally active HIV - 1 non-nucleoside reverse transcriptase inhibitor (NNRTI) with an IC50 of 0.081 μM against WT HIV-1 reverse transcriptase. It has particularly strong antiviral activity with EC50s of 4.44-54.5 nM against various HIV-1 strains. Synonyms: (E)-4-((4-(4-(2-cyanovinyl)-2,6-dimethylphenoxy)-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidin-2-yl)amino)benzonitrile. Molecular formula: C25H21N5OS. Mole weight: 439.53.
HIV-1 inhibitor-9
HIV-1 inhibitor-9 is a potent inhibitor against the wild-type (WT) HIV-1 strains or multiple NNRTI-resistant strains at low nanomolar levels. Synonyms: CHEMBL4875519|HIV-1 inhibitor-9|BDBM50575074|CS-0226407. Grade: ≥98% (HPLC). CAS No. 2708201-36-7. Molecular formula: C24H21N5O. Mole weight: 395.46.
HIV-1 integrase inhibitor
HIV-1 integrase inhibitor is uesful for anti-HIV, which can target HIV-1 integrase and depress the activity in the treatment of HIV infection, AIDS, and other similar diseases characterized by integration of a retroviral genome into a host chromosome. Synonyms: (Z)-4-(3-(azidomethyl)phenyl)-2-hydroxy-4-oxobut-2-enoic acid. Grade: >98%. CAS No. 544467-07-4. Molecular formula: C11H9N3O4. Mole weight: 247.21.
HIV-1 integrase inhibitor 2
HIV-1 integrase inhibitor 2 is useful for anti-HIV, which can target HIV-1 integrase and depress the activity in the treatment of HIV infection, AIDS, and other similar diseases characterized by integration of a retroviral genome into a host chromosome. It did not affect integrase-DNA binding and only weakly inhibited the catalytic activities of integrase. Synonyms: CX04328; CX-04328; CX 04328; 3-Quinolineacetic acid, 6-chloro-2-methyl-4-phenyl-a-propyl-. Grade: >98%. CAS No. 957890-42-5. Molecular formula: C21H20ClNO2. Mole weight: 353.84.
HIV-1 integrase inhibitor 3
HIV-1 integrase inhibitor 3 is an HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 2.7 nM. Synonyms: 1,8-Naphthyridine-3-carboxamide, 4-amino-N-[(2,4-difluorophenyl)methyl]-1,2-dihydro-1-hydroxy-6-(5-hydroxypentyl)-2-oxo-; 4-Azanyl-N-[[2,4-bis(fluoranyl)phenyl]methyl]-1-oxidanyl-2-oxidanylidene-6-(5-oxidanylpentyl)-1,8-naphthyridine-3-carboxamide; 4-Amino-N-(2,4-difluorobenzyl)-1-hydroxy-6-(5-hydroxypentyl)-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide. Grade: ≥95%. CAS No. 1638504-56-9. Molecular formula: C21H22F2N4O4. Mole weight: 432.42.
HIV-1 integrase inhibitor 4
HIV-1 integrase inhibitor 4 is an HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 3.7 nM. Synonyms: 1,8-Naphthyridine-3-carboxamide, 4-amino-N-[(2,4-difluorophenyl)methyl]-1,2-dihydro-1-hydroxy-2-oxo-6-[2-(phenylsulfonyl)ethyl]-; 4-Azanyl-N-[[2,4-bis(fluoranyl)phenyl]methyl]-1-oxidanyl-2-oxidanylidene-6-[2-(phenylsulfonyl)ethyl]-1,8-naphthyridine-3-carboxamide; 4-Amino-N-(2,4-difluorobenzyl)-1-hydroxy-2-oxo-6-[2-(phenylsulfonyl)ethyl]-1,2-dihydro-1,8-naphthyridine-3-carboxamide. Grade: ≥95%. CAS No. 1638504-66-1. Molecular formula: C24H20F2N4O5S. Mole weight: 514.50.
HIV-1 Nef-IN-1
HIV-1 Nef-IN-1, an inhibitor of HIV-1 Nef protein, can effectively compete for Nef-SH3Hck interactions with a Kd of 6.7 μM. Synonyms: 4-(3-Phenanthryl)butanoic acid; 3-Phenanthrenebutanoic Acid; 3-Phenanthrenebutyric Acid; NSC 92828; 3-(1-Phenanthryl)butanoic acid; 1-Phenanthrenepropanoic acid, β-methyl-. Grade: ≥95%. CAS No. 13728-56-8. Molecular formula: C18H16O2. Mole weight: 264.32.