BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| H 151 | H 151 is a highly potent, selective STING antagonist, which reduces TBK1 phosphorylation and suppresses human STING palmitoylation. Synonyms: H-151; H151; Urea, N-(4-ethylphenyl)-N'-1H-indol-3-yl-; N-(4-Ethylphenyl)-N'-1H-indol-3-yl-urea; N-(4-Ethylphenyl)-N'-1H-indol-3-ylurea; H 151 (pharmacological agent). Grade: ≥98%. CAS No. 941987-60-6. Molecular formula: C17H17N3O. Mole weight: 279.34. |  |
| H2L5186303 | H2L5186303 is a potent and selective lysophosphatidic acid 2 (LPA2) receptor antagonist (IC50 = 8.9, 1230 and 27354 nM for LPA2, LPA3 and LPA1 receptors respectively, in a LPA-elicited calcium mobilization assay). Synonyms: H2L5186303; H2L 5186303; H2L-5186303; (Z,Z)-4,4'-[1,3-Phenylenebis(oxy-4,1-phenyleneimino)]bis[4-oxo-2-butenoic acid. Grade: ≥98% by HPLC. CAS No. 139262-76-3. Molecular formula: C26H20N2O8. Mole weight: 488.45. | |
| H2L 5765834 | H2L 5765834 is an antagonist of the lysophosphatidic acid receptors LPA1, LPA5 and LPA3 (IC50 = 94, 463 and 752 nM, respectively). H2L 5765834 may be used for the treatment of systemic sclerosis. Uses: Potential treatment of systemic sclerosis. Synonyms: H2L 5765834; H2L5765834; H2L-5765834; 2,3-Dihydro-2-[3-(4-nitrophenoxy)phenyl]-1,3-dioxo-1H-isoindole-5-carboxylic acid; 2-[3-(4-nitrophenoxy)phenyl]-1,3-dioxoisoindole-5-carboxylic acid. Grade: ≥99% by HPLC. CAS No. 420841-84-5. Molecular formula: C21H12N2O7. Mole weight: 404.33. | |
| H3B-120 | H3B-120 is a competitive and allosteric inhibitor of carbamoyl phosphate synthetase 1 (CPS1) with antitumor activity. A carbamoyl phosphate assay revealed that H3B-120 inhibited carbamoyl phosphate synthetase activity of CPS1 with IC50 of ~1.5 mM. Synonyms: N1-Benzyl-N1-methyl-N4-(4-methylthiazol-2-yl)piperidine-1,4-dicarboxamide. CAS No. 2194903-42-7. Molecular formula: C19H24N4O2S. Mole weight: 372.48. | |
| H3B-5942 | H3B-5942 is a selective, irreversible and covalent antagonist of estrogen receptor, which inactivates both ERα WT and ERα mutation. CAS No. 2052128-15-9. Molecular formula: C31H34N4O2. Mole weight: 494.63. | |
| H3B-6527 | H3B-6527 is a potent, highly selective and orally active FGFR4 inhibitor with potential antineoplastic activity. Synonyms: N-{2-[(6-{[(2,6-Dichloro-3,5-dimethoxyphenyl)carbamoyl](methyl)amino}-4-pyrimidinyl)amino]-5-(4-ethyl-1-piperazinyl)phenyl}acrylamide; H3B-6527; H3B 6527; H3B6527. CAS No. 1702259-66-2. Molecular formula: C29H34Cl2N8O4. Mole weight: 629.543. | |
| H3B-6545 | H3B-6545, an orally bioavailable, potent and selective estrogen receptor covalent antagonist (SERCA), is used in the study of metastatic ER-positive and HER2-negative breast cancer. Synonyms: 2-Butenamide, N,N-dimethyl-4-[[2-[[5-[(1Z)-4,4,4-trifluoro-1-(3-fluoro-1H-indazol-5-yl)-2-phenyl-1-buten-1-yl]-2-pyridinyl]oxy]ethyl]amino]-, (2E)-; (2E)-N,N-Dimethyl-4-{[2-({5-[(1Z)-4,4,4-trifluoro-1-(3-fluoro-1H-indazol-5-yl)-2-phenyl-1-buten-1-yl]-2-pyridinyl}oxy)ethyl]amino}-2-butenamide. Grade: ≥95%. CAS No. 2052130-80-8. Molecular formula: C30H29F4N5O2. Mole weight: 567.58. | |
| H3B-6545 hydrochloride | H3B-6545 hydrochloride, an orally bioavailable, potent and selective estrogen receptor covalent antagonist (SERCA), is used in the study of metastatic ER-positive and HER2-negative breast cancer. Synonyms: (2E)-N,N-Dimethyl-4-{[2-({5-[(1Z)-4,4,4-trifluoro-1-(3-fluoro-1H-indazol-5-yl)-2-phenyl-1-buten-1-yl]-2-pyridinyl}oxy)ethyl]amino}-2-butenamide hydrochloride (1:1); 2-Butenamide, N,N-dimethyl-4-[[2-[[5-[(1Z)-4,4,4-trifluoro-1-(3-fluoro-1H-indazol-5-yl)-2-phenyl-1-buten-1-yl]-2-pyridinyl]oxy]ethyl]amino]-, (2E)-, hydrochloride (1:1). Grade: ≥95%. CAS No. 2052132-51-9. Molecular formula: C30H30ClF4N5O2. Mole weight: 604.04. | |
| H3 receptor-MO-1 | H3 receptor-MO-1 is a histamine H3 receptor modulator. Synonyms: Benzamide, 4-[(1S,2S)-2-[[(2R)-4-cyclobutyl-2-methyl-1-piperazinyl]carbonyl]cyclopropyl]-; 4-[(1S,2S)-2-{[(2R)-4-Cyclobutyl-2-methyl-1-piperazinyl]carbonyl}cyclopropyl]benzamide. Grade: ≥95%. CAS No. 1240914-03-7. Molecular formula: C20H27N3O2. Mole weight: 341.45. | |
| H3R-IN-1 Hydrochloride | H3R-IN-1 Hydrochloride is a histamine receptor 3 (H3R) inverse agonist. (Extracted from patent WO2013107336A1, compound example 2). Synonyms: 4-{[3-(1,3-Benzodioxol-5-yl)-1,2,4-oxadiazol-5-yl]methyl}-1-cyclobutylpiperidine hydrochloride (1:1); Piperidine, 4-[[3-(1,3-benzodioxol-5-yl)-1,2,4-oxadiazol-5-yl]methyl]-1-cyclobutyl-, hydrochloride (1:1). Grade: ≥95%. Molecular formula: C19H24ClN3O3. Mole weight: 377.87. | |
| H4R antagonist 1 | H4R antagonist 1, a potent and highly selective antagonist of histamine H4 receptor (H4R) with an IC50 of 27 nM, has no significant binding affinity for other histamine receptor subtypes H1R, H2R, and H3R. Synonyms: 1-(8-bromopyrido[2,3-e]tetrazolo[1,5-a]pyrazin-4-yl)-N-methylazetidin-3-amine; 1-(8-Bromopyrido[2,3-e]tetrazolo[1,5-a]pyrazin-4-yl)-N-methyl-3-azetidinamine; 3-Azetidinamine, 1-(8-bromopyrido[2,3-e]tetrazolo[1,5-a]pyrazin-4-yl)-N-methyl-. Grade: ≥95%. CAS No. 1429375-54-1. Molecular formula: C11H11BrN8. Mole weight: 335.16. | |
| H4 Receptor antagonist 1 | H4 Receptor antagonist 1 is a potent and selective inverse agonist of histamine H4 receptor, with an IC50 of 19 nM. Synonyms: Benzofuro[3,2-d]pyrimidine, 8-chloro-2-methyl-4-(4-methyl-1-piperazinyl)-; 8-Chloro-2-methyl-4-(4-methyl-1-piperazinyl)[1]benzofuro[3,2-d]pyrimidine. Grade: ≥95%. CAS No. 848217-00-5. Molecular formula: C16H17ClN4O. Mole weight: 316.79. | |
| H-7 dihydrochloride | H-7 dihydrochloride is a protein kinase inhibitor (IC50 = 6.0, 5.8, 3.0 and 97.0 μM for inhibition of PKC, PKG, PKA and myosin light chain kinase, respectively). H-7 inhibits cell invasion and metastasis in B16BL6 cancer cells through the PKC/MEK/ERK pathway. It was also shown to inhibit Topo I and II in murine L929 cells and induce apoptosis via PKC inhibition. Synonyms: H7 dihydrochloride; H7 HCl. (±)-1-(5-Isoquinolinesulphonyl)-2-methylpiperazine dihydrochloride. Grade: ≥99% by HPLC. CAS No. 108930-17-2. Molecular formula: C14H17N3O2S.2HCl. Mole weight: 364.29. | |
| H 89 | Selective inhibitor of Protein Kinase A (cyclic AMP-dependeant Protein Kinase) with an inhibitory constant of 0.0048 uM. Synonyms: Protein kinase inhibitor H-89; H89; H 89. Grade: >98%. CAS No. 127243-85-0. Molecular formula: C20H20BrN3O2S. Mole weight: 446.36. | |
| H 89 2HCl | H 89 2HCl is a cell permeable and potent PKA inhibitor with Ki of 48 nM in a cell-free assay, wihich is 10-fold selective for PKA than PKG, 500-fold greater selectivity than PKC, MLCK, calmodulin kinase II and casein kinase I/II. Synonyms: N-[2-[[3-(4-Bromophenyl)-2-propenyl]amino]ethyl]-5-isoquinolinesulfonamide dihydrochloride. Grade: ≥98%. CAS No. 130964-39-5. Molecular formula: C20H20BrN3O2S·2HCl. Mole weight: 519.28. | |
| H-8 dihydrochloride | H-8 is a cell-permeable and potent inhibitor of PKA and PKG with Ki values of 1.2 and 0.48 μM, respectively. It also slightly inhibits PKC and MLCK with Ki values of 15 and 68 μM. Synonyms: N-[2-(Methylamino)ethyl]-5-isoquinolinesulfonamide dihydrochloride. Grade: ≥98%. CAS No. 113276-94-1. Molecular formula: C12H15N3O2S·2HCl. Mole weight: 338.3. | |
| H-9 dihydrochloride | H-9 dihydrochloride is a protein kinase inhibitor. It inhibits PKA (Ki = 1.9 μM), PKG (Ki = 0.9 μM), CaMK II (Ki = 60 μM), PKC (Ki = 18 μM), casein kinase I (Ki = 110 μ M) and casein kinase II (Ki > 300 μM). H-9 hydrochloride reduces the cAMP-mediated excitatory response to serotonin in C. elegans enteric neurons2 and inhibits PKA-mediated phosphorylation in a rat seizure model. Synonyms: H-9 dihydrochloride; H 9 dihydrochloride; H9 dihydrochloride; N-(2-Aminoethyl)-5-isoquinolinesulfonamide dihydrochloride. Grade: ≥99% by HPLC. CAS No. 116700-36-8. Molecular formula: C11H13N3O2S.2HCl. Mole weight: 324.22. | |
| HA-1004 | HA-1004 is a potent inhibitor of PKA and PKG with Ki values of 2.3 and 1.4 μM, respectively. It also inhibits PKC and calcium channel protein. HA-1004 was studied as a relaxant for rabbit aortic strips contracted by various agonists, suggesting its potential use for vasorelaxation. It is also an inhibitor of PKC and MLC. Synonyms: 5-Isoquinolinesulfonamide, N-[2-[(aminoiminomethyl)amino]ethyl]-; N-[2-[(Aminoiminomethyl)amino]ethyl]-5-isoquinolinesulfonamide; HA 1004; HA1004; HT 1004; HT-1004; HT1004; N-(2-Guanidinoethyl)-5-isoquinolinesulfonamide; N-(2-guanidinoethyl)isoquinoline-5-sulfonamide. Grade: ≥95%. CAS No. 91742-10-8. Molecular formula: C12H15N5O2S. Mole weight: 293.34. | |
| HA-1004 dihydrochloride | HA-1004 dihydrochloride is an inhibitor of PKA, PKC, cGKI, MYLK, and calcium channel protein. Synonyms: 5-Isoquinolinesulfonamide, N-[2-[(aminoiminomethyl)amino]ethyl]-, hydrochloride (1:2); 5-Isoquinolinesulfonamide, N-[2-[(aminoiminomethyl)amino]ethyl]-, dihydrochloride; HA 1004 dihydrochloride; HA1004 dihydrochloride; N-(2-guanidinoethyl)-5-isoquinolinesulfonamide dihydrochloride. Grade: ≥98%. CAS No. 92564-08-4. Molecular formula: C12H15N5O2S.2HCl. Mole weight: 366.27. | |
| HA-1004 monohydrochloride | HA-1004 is a potent inhibitor of PKA and PKG with Ki values of 2.3 and 1.4 μM, respectively. It also inhibits PKC and calcium channel protein. HA-1004 was studied as a relaxant for rabbit aortic strips contracted by various agonists, suggesting its potential use for vasorelaxation. Uses: A novel calcium antagonist and vasodilator with no effect on cardiac function. Synonyms: 5-Isoquinolinesulfonamide, N-[2-[(aminoiminomethyl)amino]ethyl]-, hydrochloride (1:1); 5-Isoquinolinesulfonamide, N-[2-[(aminoiminomethyl)amino]ethyl]-, monohydrochloride; HA 1004 hydrochloride; N-(2-Guanidinoethyl)-5-isoquinolinesulfonamide Hydrochloride; N-[2-[(Aminoiminomethyl)amino]ethyl]-5-isoquinolinesulfonamide Monohydrochloride. Grade: 95%. CAS No. 92564-34-6. Molecular formula: C12H15N5O2S.HCl. Mole weight: 329.81. | |
| HA-100 Dihydrochloride | HA-100 is an inhibitor of protein kinases including PKA, PKC, and PKG. HA-100 dihydrochloride was reported to increase human fibroblast reprogramming efficiency in combination with PD0325901, CHIR99021, A83-01 and hLIF. Synonyms: 5-(Piperazine-1-sulfonyl)isoquinoline dihydrochloride. Grade: >98%. CAS No. 210297-47-5. Molecular formula: C13H15N3O2S·2HCl. Mole weight: 350.3. | |
| HA-100 hydrochloride | HA-100 hydrochloride is a potent protein kinase inhibitor, with IC50s of 4 μM, 8 μM, 12 μM and 240 μM for cGMP-dependent protein kinase (PKG), cAMP-dependent protein kinase (PKA), protein kinase C (PKC) and MLC-kinase, respectively. It exhibits potent inhibition toward protein kinase C and cyclic nucleotide dependent protein kinases. Uses: Exhibited potent inhibition toward protein kinase c and cyclic nucleotide dependent protein kinases. Synonyms: 1-(5-Isoquinolinesulfonyl)piperazine hydrochloride; 5-(piperazin-1-ylsulfonyl)isoquinoline hydrochloride. CAS No. 141543-63-7. Molecular formula: C13H16ClN3O2S. Mole weight: 313.80. | |
| HA-1077 dihydrochloride | HA-1077 is a potent and selective inhibitor of Rho kinase (ROCK). HA-1077 exhibited neuroprotective effects and enhanced cognition in mouse models of amyotrophic lateral sclerosis (ALS), suggesting its potential use for cognitive disorders such as ALS, Alzheimer's disease and spinal muscular atrophy. It also suppresses tumor cell motility and metastasis. Synonyms: Fasudil dihydrochloride; 5-((1,4-Diazepan-1-yl)sulfonyl)isoquinoline dihydrochloride. Grade: ≥98%. CAS No. 203911-27-7. Molecular formula: C14H17N3O2S·2HCl. Mole weight: 364.3. | |
| HA-130 | HA-130, an effective autotaxin (ATX) inhibitor, has been found to restrain the cell migration related to ATX in in an A2058 melanoma cells. IC50: 28 nM. Uses: Ha-130 is an effective autotaxin (atx) inhibitor that has been found to restrain the cell migration related to atx in in an a2058 melanoma cells. Synonyms: SCHEMBL1555945; 1229652-21-4; HA130; HA-130; HA 130. Grade: >98 %. CAS No. 1229652-21-4. Molecular formula: C24H19BFNO5S. Mole weight: 463.29. | |
| HA14-1 | HA14-1 is a potent Bcl-2 inhibitor with potential anticancer activity. HA14-1 induces apoptosis in various human cancer cells. HA14-1 suppressed NF-kappaB activation through inhibition of phosphorylation and degradation of IkappaBalpha. Synonyms: HA-141, HA 141, HA141. CAS No. 65673-63-4. Molecular formula: C17H17BrN2O5. Mole weight: 409.23. | |
| Ha-15 | HA-15 is a compound that targets BiP/GRP78/HSPA5 with an antitumor activity on all melanoma cells. Uses: Ha-15 is a compound that targets bip/grp78/hspa5 with an antitumor activity. Synonyms: HA15; HA 15; N-(4-(3-((5-(dimethylamino)naphthalene)-1-sulfonamido)phenyl)thiazol-2-yl)acetamide. Grade: ≥98%. CAS No. 1609402-14-3. Molecular formula: C23H22N4O3S2. Mole weight: 466.574. | |
| HA-155 | HA-155 is an autotaxin inhibitor. Autotaxin, also known as ectonucleotide pyrophosphatase/phosphodiesterase 2 (NPP2 or ENPP2), is a secreted enzyme converting lysophosphatidylcholine (LPC) into lysophosphatidic acid (LPA), which is responsible for tumor cell motility stimulation. Synonyms: HA 155; HA155; Autotaxin Inhibitor IV; Boronic acid, B-[4-[[4-[[3-[(4-fluorophenyl)methyl]-2,4-dioxo-5-thiazolidinylidene]methyl]phenoxy]methyl]phenyl]-. Grade: ≥95%. CAS No. 1229652-22-5. Molecular formula: C24H19BFNO5S. Mole weight: 463.3. | |
| hA3AR agonist 1 | HA3AR agonist 1 is a potent human A3 adenosine receptor agonist with a Ki value of 2.40 nM. Synonyms: hA3AR agonist 1; CHEMBL5075606; compound 6c [PMID: 34435786]; GTPL11706; BDBM50580163; CS-0254059; ((2R,3R,4S)-4-Amino)-2-(6-(methylamino)-9H-purin-9-yl)tetrahydrothiophen-3-ol. Molecular formula: C10H14N6OS. Mole weight: 266.32. | |
| HAC-Y6 | HAC-Y6 is a novel and potent microtubule inhibitor. HAC-Y60 exhibited potent antitumor activity against human hepatocellular carcinoma (HCC) cells in vitro. Synonyms: HACY6; HAC Y6; 6-acetyl-9-(3,4,5-trimethoxybenzyl)-9h-pyrido [2,3-b]indole. Grade: 98%. CAS No. 1331959-78-4. Molecular formula: C23H22N2O4. Mole weight: 390.43. | |
| Halazone | Halazone is an atypical antimicrobial sulfonamide derivative and carbonic anhydrase II inhibitor with a Kd of 1.45 μM. Halazone protects sodium channels from inactivation, and is widely used to disinfect drinking water. Synonyms: Pantocide; 4-[(dichloroamino)sulfonyl]benzoic acid; p-Sulfondichloramidobenzoic acid; p-(N,N-Dichlorosulfamyl)benzoic acid; Halazon; Pantocid; Cloritines; Zeptabs; 4-(N,N-Dichlorosulfamoyl)benzoic acid; p-Carboxybenzenesulfondichloroamide; NSC 60717. Grade: ≥90%. CAS No. 80-13-7. Molecular formula: C7H5Cl2NO4S. Mole weight: 270.09. | |
| Halcinonide | Halcinonide is a high potency corticosteroid used in topical preparations as an anti-inflammatory agent. Synonyms: Pregn-4-ene-3,20-dione, 21-chloro-9-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (11β,16α)-; (11β,16α)-21-Chloro-9-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregn-4-ene-3,20-dione; Pregn-4-ene-3,20-dione, 21-chloro-9-fluoro-11β,16α,17-trihydroxy-, cyclic 16,17-acetal with acetone; Adcortin; Alcinonide; Halciderm; Halcimat; Halog; SQ 18566. Grade: >98%. CAS No. 3093-35-4. Molecular formula: C24H32ClFO5. Mole weight: 454.96. | |
| Halicloic acid A | Halicloic acid A is a potent IDO inhibitor. Synonyms: Halicloic Acid A; CHEMBL2087614; BDBM50421038; 4-(4'-(2''-methoxy-4''-hydroxy-3'',6''-dimethylbenzoyloxy)-3',5',6'-trimethyl-2'-methoxybenzoyloxy)-2-methoxy-3,6-dimethylbenzoic acid. Grade: > 98%. CAS No. 1393581-27-5. Molecular formula: C38H56O5. Mole weight: 592.85. | |
| Halobetasol | Halobetasol is a corticosteroid, an anti-inflammatory drug that is used to treat various dermatological conditions which mainly consist of various forms of psoriasis. Uses: Vasoconstrictor agents. Synonyms: Ulobetasol; (6α,11β,16β)-21-chloro-6,9-difluoro-11,17-dihydroxy-16-methyl-Pregna-1,4-diene-3,20-dione. Grade: 98%. CAS No. 98651-66-2. Molecular formula: C22H27ClF2O4. Mole weight: 428.90. | |
| Halobetasol-d3 | Halobetasol-d3 is a labelled Halobetasol. Halobetasol is a corticosteroid used for the treatment of skin conditions such as psoriasis. Synonyms: (6α,11β,16β)-21-chloro-6,9-difluoro-11,17-dihydroxy-16-methyl-Pregna-1,4-diene-3,20-dione-d3; Ulobetasol-d3. Grade: > 95%. Molecular formula: C22H24ClF2O4D3. Mole weight: 431.93. | |
| Halobetasol-d3 Propionate | Halobetasol-d3 Propionate is a labelled Halobetasol Propionate. Halobetasol Propionate is a medication used to treat skin conditions such as dermatitis and allergies. Grade: > 95%. Molecular formula: C25H28ClF2O5D3. Mole weight: 487.99. | |
| Halobetasol Dipropionate | Halobetasol Dipropionate shines as a vital corticosteroid within the biomedical secto used in studying an array of skin afflictions, encompassing eczema, psoriasis, and dermatitis. Grade: > 95%. CAS No. 886204-51-9. Molecular formula: C28H35ClF2O6. Mole weight: 541.04. | |
| Halobetasol Propionate | Halobetasol propionate act by the induction of phospholipase A2 inhibitory proteins. Uses: Vasoconstrictor agents. Synonyms: Vitamin B1. Grade: >98%. CAS No. 66852-54-8. Molecular formula: C25H31ClF2O5. Mole weight: 484.96. | |
| Halobetasol Propionate Impurity B | Halobetasol Propionate Impurity B. Synonyms: 21-Acetate 17-propionate diflorasone; 79861-38-4; UNII-U962JX023W; U962JX023W; [(6S,8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-acetyloxyacetyl)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate; 21-Acetoxy-21-deschloro Halobetasol 17-Propionate; Q27290944; 6.ALPHA.,9-DIFLUORO-11.BETA.,17,21-TRIHYDROXY-16.BETA.-METHYLPREGNA-1,4-DIENE-3,20-DIONE 21-ACETATE 17-PROPIONATE; HALOBETASOL PROPIONATE IMPURITY, 21-ACETATE 17-PROPIONATE DIFLORASONE- [USP IMPURITY]; PREGNA-1,4-DIENE-3,20-DIONE, 21-(ACETYLOXY)-6,9-DIFLUORO-11-HYDROXY-16-METHYL-17-(1-OXOPROPOXY)-, (6.ALPHA.,11.BETA.,16.BETA.)-. Grade: > 95%. CAS No. 79861-38-4. Molecular formula: C27H34F2O7. Mole weight: 508.56. | |
| Halobetasol Propionate Impurity C | Halobetasol Propionate Impurity C. Synonyms: 11-Propionate 21- chloro diflorasone; 181527-42-4; UNII-37T2132Q01; 37T2132Q01; 11-Propionate 21-chloro diflorasone; [(6S,8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-chloroacetyl)-6,9-difluoro-17-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-11-yl] propanoate; DTXSID80171161; Q27256697; 21-CHLORO-6.ALPHA.,9-DIFLUORO-11.BETA.,17-DIHYDROXY-16.ALPHA.-METHYLPREGNA-1,4-DIENE-3,20-DIONE 11-PROPIONATE; HALOBETASOL PROPIONATE IMPURITY, 11-PROPIONATE 21- CHLORO DIFLORASONE- [USP IMPURITY]; PREGNA-1,4-DIENE-3,20-DIONE, 21-CHLORO-6,9-DIFLUORO-17-HYDROXY-16-METHYL-11-(1-OXOPROPOXY)-, (11.BETA.)-. Grade: > 95%. CAS No. 181527-42-4. Molecular formula: C25H31ClF2O5. Mole weight: 484.97. | |
| Halobetasol Propionate Impurity D | Halobetasol Propionate Impurity D. Synonyms: 9-Chloro halobetasol propionate; UNII-7P6H3332RL; 66852-61-7; 7P6H3332RL[(6S,8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-17-(2-chloroacetyl)-6-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate. Grade: > 95%. CAS No. 66852-61-7. Molecular formula: C25H31Cl2FO5. Mole weight: 501.43. | |
| Halobetasol Propionate Impurity E | Halobetasol Propionate Impurity E. Grade: > 95%. Molecular formula: C25H31Cl2FO5. Mole weight: 501.43. | |
| halocarban | Halocarban is a disinfectant agent with antibacterial properties. Synonyms: Cloflucarban; Irgasan CF3; Halocarbano; 4,4'-Dichloro-3-(trifluoromethyl)carbanilide. CAS No. 369-77-7. Molecular formula: C14H9Cl2F3N2O. Mole weight: 349.13. | |
| Halofantrine Hydrochloride | Halofantrine is a blocker of delayed rectifier potassium current via the inhibition of hERG channel used to treat malaria. Uses: A blocker of delayed rectifier potassium. Synonyms: 1,3-dichloro-alpha-[2-(dibutylamino)ethyl]-6- (trifluoromethyl)-9-phenathrenemethanol hydrochloride; halofantrine hydrochloride; 1,3-dichloro-alpha-[2-(dibutylamino)ethyl]-6-(trifluoromethyl)phenanthren-1-methanol hydrochloride; Halofantarine HCL; Halfan, 1. Grade: >98% BP/EP. CAS No. 36167-63-2. Molecular formula: C26H30Cl2F3NO.ClH. Mole weight: 536.89. | |
| Halofuginone | Halofuginone is a semisynthetic quinazolinone alkaloid anticoccidial derived from the plant Dichroa febrifuga, with antifibrotic and potential antineoplastic activities. Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor cell growth. These effects appear to be due to halofuginone-mediated inhibition of the collagen type I and MMP-2 promoters. Collagen type I and MMP-2 play important roles in fibro-proliferative diseases. Uses: Semisynthetic quinazolinone alkaloid anticoccidial. Synonyms: Halofuginone; Tempostatin; RU 19110; RU19110; RU-19110. Grade: > 95%. CAS No. 55837-20-2. Molecular formula: C16H17BrClN3O3. Mole weight: 414.684. | |
| Halofuginone Hydrochloride | Halofuginone Hydrochloride is the hydrochloride salt preparation of Halofuginone. Synonyms: rel-7-Bromo-6-chloro-3-[3-[(2R,3S)-3-hydroxy-2-piperidinyl]-2-oxopropyl]-4(3H)-quinazolinone Hydrochloride; 7-Bromo-6-chlorofebrifugine Hydrochloride; HAL. Grade: > 95%. CAS No. 1217623-74-9. Molecular formula: C16H18BrCl2N3O3. Mole weight: 451.15. | |
| Halofuginone lactate | Halofuginone lactate is a halogenated derivative of febrifugine. Halofuginone inhibits prolyl-tRNA synthetase in an ATP-dependent manner with a Ki of 18.3 nM. Grade: >95%. CAS No. 82186-71-8. Molecular formula: C19H23BrClN3O6. Mole weight: 504.76. | |
| Halometasone Impurity 1 | Halometasone Impurity 1. Grade: > 95%. Molecular formula: C22H27ClF2O5. Mole weight: 444.91. | |
| Halometasone Impurity 2 | Halometasone Impurity 2. Grade: > 95%. Molecular formula: C20H23ClF2O3. Mole weight: 384.85. | |
| Halometasone Impurity 3 | Halometasone Impurity 3. Grade: > 95%. Molecular formula: C21H25ClF2O5. Mole weight: 430.88. | |
| Halometasone Impurity 4 | Halometasone Impurity 4. Grade: > 95%. Molecular formula: C22H25ClF2O5. Mole weight: 442.89. | |
| Halometasone Impurity 5 | Halometasone Impurity 5. Grade: > 95%. Molecular formula: C22H27ClF2O5. Mole weight: 444.91. | |
| Halometasone Impurity 6 | Halometasone Impurity 6. Grade: > 95%. Molecular formula: C22H27ClF2O6. Mole weight: 460.91. | |
| Halopemide | Halopemide is a potent inhibitor of phospholipase D (PLD), and also a dopamine blocker. It is structurally related to butyrophenones and acts as a psychotropic agent, without parkinsonian side effects. Synonyms: NSC 354856; R34301; N-[2-[4-(5-chloro-2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]ethyl]-4-fluorobenzamide. Grade: ≥98%. CAS No. 59831-65-1. Molecular formula: C21H22ClFN4O2. Mole weight: 416.9. | |
| Haloprogin | Haloprogin is an antifungal drug. It can be used for the treatment of athlete's foot and other fungal infections. Uses: Athlete's foot and other fungal infections. Synonyms: M 1028; NSC 100071; M1028; NSC100071; M-1028; NSC-100071; 1,2,4-Trichloro-5-[(3-iodo-2-propynyl)oxy]benzene; 2,4,5-Trichlorophenyl γ-Iodopropargyl Ether; 3-Iodo-2-propynyl 2,4,5-Trichlorophenyl Ether; 1,2,4-Trichloro-5-[(3-iodo-2-propyn-1-yl)oxy]benzene. Grade: 98%. CAS No. 777-11-7. Molecular formula: C9H4Cl3IO. Mole weight: 361.39. | |
| Halopyramine | Halopyramine is known as a competitive reversible H1-receptor antagonist. It exerts its pharmacological action by competing with histamine for the H1 subtype histamine receptor. It inhibits the vasodilation, increased vascular permeability, and tissue edema associated with histamine release in the tissue by blocking the effects of histamine. It is a first generation antihistamine drug for the treatment of allergic rhinitis, allergic conjunctivitis, bronchial asthma, and other allergic conditions. It has been listed. Uses: Halopyramine is a first generation antihistamine drug for the treatment of allergic rhinitis, allergic conjunctivitis, bronchial asthma, and other allergic conditions. Synonyms: N-[(4-Chlorophenyl)methyl]-N,N-dimethyl N-2-pyridinyl-1,2-ethanediamine; 2-[(p-Chlorobenzyl)(2-dimethylaminoethyl)amino]pyridine; Allergan S; Avapena; Chlorneoantergan; Chloropyramine; Chloropyribenzamine; Chlorpyramine; N,N-Dimethyl-N'-(2-pyridyl)-N'-(4-chlorobenzyl)ethylenediamine; N,N-Dimethyl-N'-(p-chlorobenzyl)-N'-(2-pyridyl)ethylenediamine; N-[(4-Chlorophenyl)methyl]-N-[2-(dimethylamino)ethyl]pyridine-2-amine; N-Dimethylaminoethyl-N-pchlorobenzyl-α-aminopyridine; NSC 241038; N'-[(4-Chlorophenyl)methyl]-N,N-dimethyl-N'-pyridin-2-yl-ethane-1,2-diamine; Subrestin; Suprastin; Synopen; Synopen R; Synpen. Grade: 98%. CAS No. 59-32-5. Molecular formula: C16H20ClN3. Mole weight: 289.81. | |
| HaloTag O2 Tobramycin | HaloTag O2 Tobramycin is a derivative compound of Tobramycin, a single factor antibiotic comprising about 10% of nebramycin, the aminoglycosidic antibiotic complex produced by Streptomyces tenebrarius. An antibacterial. Synonyms: N-(((2R,3S,5R,6R)-5-Amino-6-(((2S,3S,4R,6S)-4,6-diamino-3-(((2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydromethyl)tetrahydro-2H-pyran-2-yl)oxy)-2-hydroxycyclohexyl)oxy-3-hydroxytetrahydro-2H-pyran-2-yl)methyl)-4-((2-(2((6-chlorohexyl)oxyl)ethoxy)ethyl)amino)butanamide; N1-(((2R,3S,5R,6R)-5-Amino-6-(((2S,3S,4R,6S)-4,6-diamino-3-(((2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2-hydroxycyclohexyl)oxy)-3-hydroxytetrahydro-2H-pyran-2-yl)methyl)-N4-(2-(2-((6-chlorohexyl)oxy)ethoxy)ethyl)succinamide. Grade: 95%. Molecular formula: C32H61ClN6O13. Mole weight: 773.31. | |
| Haloxon | Haloxon is an organophosphorus anthelmintic once used against nematodes of the abomasum and small intestine in ruminants. Synonyms: Haloxon. Grade: >98%. CAS No. 321-55-1. Molecular formula: C14H14Cl3O6P. Mole weight: 415.59. | |
| Hamaline | Hamaline is a substrate-selective inhibitor of cyclooxygenase-2 (COX-2). Synonyms: 9-[(4-chlorophenyl)methyl]-6-methoxy-1-methyl-4,9-dihydro-3H-beta-carboline. CAS No. 2411677-02-4. Molecular formula: C20H19ClN2O. Mole weight: 338.83. | |
| HAMI3379 | HAMI3379 is a cysteinyl leukotriene 2 (CysLT2) receptor antagonist. It can inhibit radioligand binding of LTD4 to CysLT2 and CysLT1 receptor cell lines with IC50 values of 37.9 and >30,000 nM. In a CysLT2 receptor reporter cell line, it can antagonize LTD4- and LTC4-induced intracellular calcium mobilization with IC50 values of 3.8 and 4.4 nM, respectively, but it only weakly inhibits that for a CysLT1 receptor reporter cell line with IC50 value >10,000 nM. HAMI3379 may represent a new type of therapeutic agent in the treatment of ischemic stroke. Uses: Ischemic stroke. Synonyms: HAMI3379; HAMI-3379; HAMI 3379; CHEMBL3342944; GTPL6197; SCHEMBL4518791; DTXSID80439859; 3-[(3-carboxycyclohexyl)carbamoyl]-4-[3-[4-(4-cyclohexyloxybutoxy)phenyl]propoxy]benzoic acid. Grade: 90%. CAS No. 712313-35-4. Molecular formula: C34H45NO8. Mole weight: 595.73. | |
| HAMNO | HAMNO is a novel protein interaction inhibitor of replication protein A (RPA), which is involved in the ATR/Chk1 pathway. HAMNO acts by binding to the N-terminal DBD-F domain of RPA70. HAMNO inhibits both ATR autophosphorylation and phosphorylation of RPA32 Ser33 by ATR. It is a potential treatment of cancer. Uses: Potential antitumor drug. Synonyms: HAMNO; CID 6335338, MLS000737724, NSC111847, NSC-111847; NSC111847. 1-(2-Hydroxyphenyliminomethyl)-2-naphthol; 2(1H)-Naphthalenone, 1-[[(2-hydroxyphenyl)amino]methylene]-. Grade: 99%. CAS No. 138736-73-9. Molecular formula: C17H13NO2. Mole weight: 263.29. | |
| Hancockiamide A | Hancockiamide A belongs to an unusual new family of N-cinnamoylated piperazines from the Australian soil fungus Aspergillus hancockii. Molecular formula: C29H32N2O4. Mole weight: 472.57. | |
| Hancockiamide A TFA salt | The TFA salt form of Hancockiamide A. Hancockiamide A belongs to an unusual new family of N-cinnamoylated piperazines from the Australian soil fungus Aspergillus hancockii. Molecular formula: C31H33F3N2O6. Mole weight: 586.60. | |
| Hancockiamide B | Hancockiamide B belongs to an unusual new family of N-cinnamoylated piperazines from the Australian soil fungus Aspergillus hancockii. Molecular formula: C31H34N2O5. Mole weight: 514.61. | |
| Hancockiamide D | Hancockiamide D belongs to an unusual new family of N-cinnamoylated piperazines from the Australian soil fungus Aspergillus hancockii. Molecular formula: C20H26N2O3. Mole weight: 342.43. | |
| Hancockiamide D TFA salt | The TFA salt form of Hancockiamide D. Hancockiamide D belongs to an unusual new family of N-cinnamoylated piperazines from the Australian soil fungus Aspergillus hancockii. Molecular formula: C22H27F3N2O5. Mole weight: 456.45. | |
| Hancockiamide E TFA salt | The TFA salt form of Hancockiamide E. Hancockiamide E belongs to an unusual new family of N-cinnamoylated piperazines from the Australian soil fungus Aspergillus hancockii. Molecular formula: C33H35F3N2O9. Mole weight: 660.63. | |
| Hancockiamide F | Hancockiamide F belongs to an unusual new family of N-cinnamoylated piperazines from the Australian soil fungus Aspergillus hancockii. Molecular formula: C31H32N2O6. Mole weight: 528.59. | |
| Hancockiamide G | Hancockiamide G belongs to an unusual new family of N-cinnamoylated piperazines from the Australian soil fungus Aspergillus hancockii. Molecular formula: C29H30N2O4. Mole weight: 470.56. | |
| Hancockiamide H | Hancockiamide H belongs to an unusual new family of N-cinnamoylated piperazines from the Australian soil fungus Aspergillus hancockii. Molecular formula: C20H24N2O3. Mole weight: 340.42. | |
| Hancockiamide I | Hancockiamide I belongs to an unusual new family of N-cinnamoylated piperazines from the Australian soil fungus Aspergillus hancockii. Molecular formula: C38H36N2O5. Mole weight: 600.70. | |
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