BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| GSK963 | GSK963 is a potent and selective inhibitor of RIP1 kinase (RIPK1; IC50=29 nM in FP binding assays). GSK963 displays >10?000-fold selective for RIP1 over 339 other kinases. Synonyms: 2,2-dimethyl-1-[(3S)-3-phenyl-3,4-dihydropyrazol-2-yl]propan-1-one. Grade: ≥98%. CAS No. 2049868-46-2. Molecular formula: C14H18N2O. Mole weight: 230.31. |  |
| GSK-F1 | PI4KA inhibitor-F1 is a potent PI4KA inhibitor. Synonyms: PI4KA inhibitor-F1. Grade: 98%. CAS No. 1384097-27-1. Molecular formula: C27H18F5N5O4S. Mole weight: 603.5. | |
| GSK J1 | GSK-J1 is a highly potent H3K27 histone demethylase inhibitor with IC50 of 28 nM and 53 nM in cell-free assays for JMJD3 (KDM6B) and UTX (KDM6A), respectively, >10-fold selectivity over other tested demethylases. Synonyms: GSKJ1; GSKJ 1; GSKJ-1. Grade: 98%. CAS No. 1373422-53-7. Molecular formula: C22H23N5O2. Mole weight: 389.45. | |
| GSK-J1 lithium salt | GSK-J1 lithium salt is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A, with an IC50 of 60 nM towards KDM6B. Synonyms: Lithium 3-{[2-(2-pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]amino}propanoate; β-Alanine, N-[2-(2-pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-, lithium salt (1:1). Molecular formula: C22H22LiN5O2. Mole weight: 395.38. | |
| GSK-J1 sodium salt | GSK-J1 is a potent and selective inhibitor of the H3K27 histone demethylases JMJD3 and UTX (IC50s = 18 and 56 μM, respectively; IC50 = 60 nM in JMJD3 antibody-based assays). Synonyms: N-[2-(2-pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine, monosodium salt. Grade: ≥95%. CAS No. 1797832-71-3. Molecular formula: C22H22N5O2·Na. Mole weight: 411.4. | |
| GSK-J2 | GSK-J2, a benzazepin derivative, has been found to have poor activity as a JMJD3 inhibitor so that could be used in the biological study of GSK-J1 as a negative control. IC50: > 100 μM. Uses: Gsk-j2 has been found to have poor activity as a jmjd3 inhibitor so that could be used in the biological study of gsk-j1 as a negative control. Synonyms: SK-J2; GSK J2; GSKJ2; 1394854-52-4; SCHEMBL15937902; 3705AH. Grade: 98%. CAS No. 1394854-52-4. Molecular formula: C22H23N5O2. Mole weight: 389.45. | |
| GSK-J2 sodium salt | GSK-J2 is a pyridine regio-isomer of GSK-J1 which poorly inhibits JMJD3 with an IC50 value greater than 100 μM. Synonyms: 3-((6-(4,5-dihydro-1H-benzo[d]azepin-3(2H)-yl)-2-(pyridin-3-yl)pyrimidin-4-yl)amino)propanoic acid, monosodium salt. Grade: ≥90%. CAS No. 2108665-15-0. Molecular formula: C22H23N5O2·Na. Mole weight: 412.4. | |
| GSK J4 HCl | GSK J4 HCl is a cell permeable prodrug of GSK J1, which is the first selective inhibitor of the H3K27 histone demethylase JMJD3 and UTX with IC50 of 60 nM and inactive against a panel of demethylases of the JMJ family. Synonyms: GSK-J4; 1373423-53-0; GSK J4; Ethyl 3-((6-(4,5-dihydro-1H-benzo[d]azepin-3(2H)-yl)-2-(pyridin-2-yl)pyrimidin-4-yl)amino)propanoateethyl 3-[[2-pyridin-2-yl-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)pyrimidin-4-yl]amino]propanoate. Grade: >98%. CAS No. 1373423-53-0. Molecular formula: C24H27N5O2.HCl. Mole weight: 453.96. | |
| GSK-J4 hydrochloride | GSK-J4 (hydrochloride) is an ethyl ester derivative of GSK-J1 which blocks demethylation of histone H3K27 with an IC50 value greater than 50 μM in vitro. Synonyms: N-[2-(2-pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine, ethyl ester, monohydrochloride. Grade: ≥95%. CAS No. 1797983-09-5. Molecular formula: C24H27N5O2·HCl. Mole weight: 454. | |
| GSK-J5 hydrochloride | GSK-J5 is a pyridine regio-isomer of GSK-J4 and it is a weak inhibitor of JMJD3 (IC50 > 100 μM), making it an ideal inactive control molecule for elucidating the functional role of JMJD3 inhibition. Synonyms: N-[2-(3-pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine, ethyl ester, monohydrochoride. Grade: ≥95%. CAS No. 1797983-32-4. Molecular formula: C24H27N5O2·HCl. Mole weight: 454. | |
| GSK-LSD1 2HCl | GSK-LSD1 2HCl is an irreversible, and selective LSD1 inhibitor with IC50 of 16 nM, > 1000 fold selective over other closely related FAD utilizing enzymes (i.e. LSD2, MAO-A, MAO-B). Synonyms: GSK LSD1 2HCl; GSK-LSD1 Dihydrochloride. Grade: >98%. CAS No. 1431368-48-7. Molecular formula: C14H22Cl2N2. Mole weight: 289.24. | |
| GsMTx4 | GsMTx4 is a mechanosensitive and stretch-activated ion channel inhibitor. It is used as a tool for identifying the role of these excitatory MSCs in normal physiology and pathology. Grade: >98%. CAS No. 1209500-46-8. Molecular formula: C185H273N49O45S6. Mole weight: 4095.86. | |
| GT1a-Oligosaccharide | GT1a-Oligosaccharide is an advanced oligosaccharide, finding applications in studying intricate neurological afflictions. Its specialized affinity towards toxins and pathogens endows it with unparalleled efficiency in studying viral invasions. Synonyms: Neu5Aca2-8Neu5Aca2-3Galb1-3GalNAcb1-4 (Neu5Aca2-3)Galb1-4Glc. Molecular formula: C59H93N4O45Na3. Mole weight: 1647.34. | |
| GT1b-Ganglioside | GT1b-Ganglioside is demonstrated to protect mouse brain cells against L-cysteine-induced damage of mitochondrial DNA and increased lipid peroxidation, suggested to operate through scavenging of OH radicals promoted by L-cysteine. GT1b-Ganglioside is also demonstrated to suppress seizures, damage to mitochondrial DNA and lipid peroxidation induced by kainic acid. Synonyms: Trisialoganglioside-GT1b (porcine brain); Ganglioside GT1b; Ganglioside G1; GT1b. Grade: >99%. CAS No. 59247-13-1. Molecular formula: C95H174N8O47. Mole weight: 2180.42. | |
| GT1b-Oligosaccharide | GT1b-Oligosaccharide is an extraordinary compound, manifesting promising applications in studying the complexities of neurological disorders and autoimmune diseases. CAS No. 75663-36-4. Molecular formula: C59H96N4O45. Mole weight: 1581.39. | |
| GT1c-Oligosaccharide | GT1c-Oligosaccharide is a remarkable compound widely utilized in studying intricate cellular mechanisms in a spectrum of ailments, such as debilitating cancers and complex neurodegenerative disorders. Synonyms: Galb1-3GalNAcb1-4(Neu5Aca2-8Neu5Aca2-8Neu5Aca2-3)Galb1-4Glc. Molecular formula: C59H93N4O45Na3. Mole weight: 1647.34. | |
| GT 2016 | GT 2016 is a high affinity and brain-penetrant histamine H3 receptor antagonist (Ki = 43.8 nM). It displays selectivity against H1 and H2 receptors (IC50 >10 μM). GT 2016 increases the release of histamine in the cerebral cortex. GT 2016 exhibits no effect on histamine methyltransferase in vitro at concentrations up to 3 μM. Synonyms: GT-2016,GT2016, GT 2016; 5-Cyclohexyl-1-[4-(1H-imidazol-5-yl)-1-piperidinyl]-1-pentanone. Grade: ≥98% by HPLC. CAS No. 152241-24-2. Molecular formula: C19H31N3O. Mole weight: 317.47. | |
| GT2-Oligosaccharide | GT2-Oligosaccharide is a multifaceted biomedical marvel, effectively aiding in the formidable research of cardiovascular diseases, cancer, and diabetes. Acting as a prowess-inducing inhibitor of α-glucosidases, this spellbinding remedy boasts unprecedented potential in orchestrating the delicate symphony of blood glucose regulation. Synonyms: GalNAcb1-4(Neu5Aca2-8Neu5Aca2-8Neu5Aca2-3)Galb1-4Glc. Molecular formula: C53H83N4O40Na3. Mole weight: 1485.20. | |
| GT3-Oligosaccharide | GT3-Oligosaccharide is an extraordinary biomedical compound emanating from pristine natural sources, acting as a potent antioxidant. It is anti-inflammatory and immunomodulatory crusader, finding applications in studying cancer, cardiovascular ailments and neurodegenerative ravages. Synonyms: Neu5Aca2-8Neu5Aca2-8Neu5Aca2-3Galb1-4Glc. Molecular formula: C45H70N3O35Na3. Mole weight: 1282.01. | |
| GT 949 | GT 949 is a potent and selective EAAT2 positive allosteric modulator (EC50 = 0.26 nM) which exhibits no significant effect on DAT, SERT and NET or NMDA receptors. Synonyms: 3-((4-Cyclohexylpiperazin-1-yl)(1-phenethyl-1H-tetrazol-5-yl)methyl)-6-methoxyquinolin-2(1H)-one. Grade: ≥98%. CAS No. 460330-27-2. Molecular formula: C30H37N7O2. Mole weight: 527.66. | |
| GTP, 100mM Sodium Solution | Guanosine triphosphate (GTP) is a guanine nucleotide containing three phosphate groups esterified to the sugar moiety. GTP functions as a carrier of phosphates and pyrophosphates involved in channeling chemical energy into specific biosynthetic pathways. GTP activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation, and activation of several intracellular kinase cascades. Proliferation and apoptosis are regulated in part by the hydrolysis of GTP by small GTPases Ras and Rho. Another type of small GTPase, Rab, plays a role in the docking and fusion of vesicles and may also be involved in vesicle formation. In addition to its role in signal transduction, GTP also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA. Synonyms: D-Guanosine 5'-triphosphate; Guanosine triphosphate; Guanosine 5'-triphosphoric acid; pppG; guanosine 5'-O-(triphosphate); [[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate. Molecular formula: C10H16N5O14P3 (free acid). Mole weight: 523.18 (free acid). | |
| GTP-14564 | GTP-14564 is a specific kinase inhibitor for ITD-FLT3. GTP-14564 inhibited the growth of interleukin-3-independent Ba/F3 expressing ITD-FLT3 at 1 microM, whereas a 30-fold higher concentration of GTP-14564 was required to inhibit FLT3 ligand-dependent growth of Ba/F3 expressing wild type FLT3 (wt-FLT3). Synonyms: GTP 14564; GTP14564; 1-Phenyl-3-H-8-oxa-2,3-diaza-cyclopenta[a]inden. CAS No. 34823-86-4. Molecular formula: C15H10N2O. Mole weight: 234.25. | |
| GTPαS (Sp isomer) | GTPαS (Sp isomer) is a non-hydrolyzable analog of GTP. It contains a sulfur atom replacing one of the non-bridging oxygen atoms in the triphosphate chain. The Sp isomer specifically refers to the stereoisomer where the sulfur atom occupies a particular spatial orientation. This compound is widely used in biochemical research to study G-protein signaling pathways, as it can activate G-proteins but is resistant to hydrolysis, thereby providing sustained signaling. Synonyms: Guanosine 5'-O-(1-thiotriphosphate), Sp-isomer; SP-GTP-αS; Guanosine, 5'→P''-ester with [P''(S)]-thiotriphosphoric acid ((HO)2P(O)OP(O)(OH)OP(O)(OH)(SH)); Guanosine, 5'→P''-ester with thiotriphosphoric acid ((HO)2P(O)OP(O)(OH)OP(S)(OH)2), (S)-. Grade: ≥95% by HPLC. CAS No. 81570-51-6. Molecular formula: C10H16N5O13P3S. Mole weight: 539.24. | |
| GTP-γ-AmNS | GTP-γ-AmNS is a fluorescent analogue of GTP used for the determination of enzymes specialized to cleave α/β-phosphodiester bonds. Synonyms: Guanosine- 5'- O- triphosphoro- γ- 1- (5- sulfonic acid)naphthylamidate, sodium salt. Grade: ≥ 95% by HPLC. CAS No. 76724-84-0. Molecular formula: C20H23N6O16P3S (free acid). Mole weight: 728.4 (free acid). | |
| GTPγS | GTPγS is a stable G-protein-activating (GTP) analog. The physiological actions of GTPgammaS includestimulation of guanine nucleotide-binding proteins, phosphoinositide hydrolysis, cyclic AMP accumulation, and activation of specific proto-oncogenes. Synonyms: Guanosine-5'-(γ-thio)-triphosphate, Tetralithium salt; Guanosine-5'-(3-thio)-triphosphate; Guanosine-5'-(3-thiotriphosphate). Grade: ≥ 90 % by HPLC, contains < 10 % GDP. CAS No. 94825-44-2. Molecular formula: C10H16N5O13P3S (free acid). Mole weight: 539.24 (free acid). | |
| G-TPP | G-TPP is a mitochondria-targeted Hsp90 inhibitor that increases cell death in HeLa and MCF7 cells, consistently inhibits cell death induced by oxidative stress and mitochondrial dysfunction induced by PINK1 mutation in mouse embryonic fibroblast cells and DA cell models such as SH-SY5Y and SN4741 cells. Additionally, G-TPP also suppresses the defective locomotive activity and DA neuron loss in Drosophila PINK1 null mutants. Synonyms: G-TPP; G TPP. Grade: >98%. CAS No. 1131626-46-4. Molecular formula: C52H65N3O8P. Mole weight: 890.85. | |
| GTS-21 | GTS-21 is a highly efficacious pharmaceutical compound used in studying the intricate afflictions of Alzheimer's disease and cognitive impairments. Uses: Nicotinic agonists. Synonyms: 3-[(2,4-Dimethoxyphenyl)methylene]-3,4,5,6-tetrahydro-2,3'-bipyridine; GTS-21; GTS21; GTS 21; DMXB-A. CAS No. 148372-04-7. Molecular formula: C19H20N2O2. Mole weight: 308.381. | |
| GTS-21 dihydrochloride | GTS-21, also known as DMBX-A, is a derivative of the natural product anabaseine that acts as a partial agonist at neural nicotinic acetylcholine receptors. It binds to both the α4β2 and α7 subtypes, but activates only the α7 to any significant extent. Synonyms: GTS-21; GTS 21; GTS21; DMBX-A. Grade: 98%. CAS No. 156223-05-1. Molecular formula: C19H20N2O2.2HCl. Mole weight: 381.30. | |
| Guaifenesin | Guaifenesin is an expectorant used to treat coughing and chest congestion. Synonyms: Guaiacol glyceryl ether; Glycerol guaiacolate. Grade: > 98 %. CAS No. 93-14-1. Molecular formula: C10H14O4. Mole weight: 198.22. | |
| Guaifenesin Impurity B | Guaifenesin Impurity B is a impurity of Guaifenesin. Synonyms: 2-(2-methoxyphenoxy)propane-1,3-diol; 1,3-Propanediol, 2-(o-methoxyphenoxy)-; 2-(o-Methoxyphenoxy)-1,3-propanediol; Brn 2049374; 1,3-Propanediol,2-(2-Methoxyphenoxy)-; 2-(2-Methoxyphenoxy)-1,3-propanediol. Grade: > 95%. CAS No. 14007-09-1. Molecular formula: C10H14O4. Mole weight: 198.22. | |
| Guaifenesin Impurity C | Guaifenesin Impurity C. Synonyms: 3,3'-oxybis(1-(2-methoxyphenoxy)propan-2-ol); 1,1'-Oxybis[3-(2-methoxyphenoxy)-2-propanol]. Grade: > 95%. Molecular formula: C20H26O7. Mole weight: 378.43. | |
| Guaifenesin Impurity D | Guaifenesin Impurity D is an impurity of Atenolol. lt is also used in various preparations of organic synthetic compounds. Synonyms: 1,3-Bis(2-methoxyphenoxy)-2-propanol; 1,3-Bis(2-methoxyphenoxy)propan-2-ol; NSC 142122. Grade: > 95%. CAS No. 16929-60-5. Molecular formula: C17H20O5. Mole weight: 304.35. | |
| Guaifenesin Metabolite | Guaifenesin Metabolite is a metabolite of the Guaifenesin. Synonyms: 3-(2-Methoxyphenoxy) Lactic Acid; Glyceryl Guaiacolate Metabolite); β-(2-Methoxyphenoxy)lactic Acid; 2-Hydroxy-3-(2-methoxyphenoxy)propanoic Acid. Grade: > 95%. CAS No. 13057-65-3. Molecular formula: C10H12O5. Mole weight: 212.20. | |
| Guanabenz | Guanabenz is an orally active agonist of alpha 2-adrenoceptor (α2 adrenergic receptor). It is used to treat high blood pressure (hypertension). Synonyms: Guanabenzacetate; Wytensin; Wy8678; Guanabenzum. Grade: 95%. CAS No. 5051-62-7. Molecular formula: C8H8Cl2N4. Mole weight: 231.08. | |
| Guanabenz Acetate | Guanabenz Acetate is an selective agonist of α2a-adrenergic receptor, α2b-adrenergic receptor and α2c-adrenergic receptor with pEC50 of 8.25, 7.01 and ~5, respectively. It is used as an antihypertensive drug. Synonyms: WY-8678 Acetate; Wytensin, WY-8678, WY 8678, WY8678, EIPA. Grade: >98%. CAS No. 23256-50-0. Molecular formula: C8H8Cl2N4.C2H4O2. Mole weight: 291.13. | |
| Guanabenz hydrochloride | Guanabenz is an agonist of α2-adrenergic receptor with hypotensive effects. Synonyms: Wytensin; 2-[(2,6-dichlorophenyl)methylene]-hydrazinecarboximidamide, monohydrochloride. Grade: ≥98%. CAS No. 23113-43-1. Molecular formula: C8H8Cl2N4·HCl. Mole weight: 267.5. | |
| Guanadrel Hemisulfate | Guanadrel, as an antihypertensive agent, is an orally active postganglionic sympathetic inhibitor. Synonyms: N-(1,4-Dioxaspiro[4.5]dec-2-ylmethyl)guanidine Sulfate; (1,4-Dioxaspiro[4.5]dec-2-ylmethyl)guanidine Sulfate; Anarel; CL 1388R; Guanadrel Sulfate; Hylorel; U 28288D. Grade: 95%. CAS No. 22195-34-2. Molecular formula: C10H19N3O2.1/2H2O4S. Mole weight: 524.636. | |
| Guanethidine | Guanethidine is an antihypertensive drug that works by inhibiting the selective transmission of postganglionic adrenergic nerves. Synonyms: Guanidine, [2-(hexahydro-1(2H)-azocinyl)ethyl]-; N-[2-(Hexahydro-1(2H)-azocinyl)ethyl]guanidine; 1-[2-(Azocan-1-yl)ethyl]guanidine; 2-(1-N,N-Heptamethyleneimino)ethylguanidine; 2-(1'-Azacyclooctyl)ethylguanidine; [2-(Octahydro-1-azocinyl)ethyl]guanidine; Abapresin; Azocine, 1-[[2-(aminoiminomethyl)amino]ethyl]octahydro-; Dopom; Eutensol; Ismelin; N-(2-Perhydroazocin-1-ylethyl)guanidine; Octatensine; Oktatensin; Oktatenzin. Grade: ≥95%. CAS No. 55-65-2. Molecular formula: C10H22N4. Mole weight: 198.31. | |
| Guanethidine hemisulfate | Guanethidine is an antihypertensive drug that works by inhibiting the selective transmission of postganglionic adrenergic nerves. Uses: Antihypertensive; antiglaucoma. Synonyms: Guanethidine sulfate; Guanidine, N-[2-(hexahydro-1(2H)-azocinyl)ethyl]-, sulfate (2:1); Guanidine, [2-(hexahydro-1(2H)-azocinyl)ethyl]-, sulfate (2:1); Guanetidin sulfate; Guethine; Iporal; Ismelin sulfate; Isobarin; NSC 29863; Octadin; Octadine; Octatensin; Oktadin; Sanotensin; Su 5864. Grade: ≥95%. CAS No. 60-02-6. Molecular formula: C10H22N4.1/2H2O4S. Mole weight: 494.70. | |
| Guanethidine sulfate | Guanethidine is an antihypertensive drug that reduces the release of catecholamines, such as norepinephrine. It is transported across the sympathetic nerve membrane by the same mechanism that transports norepinephrine itself. Once guanethidine has entered the nerve, it is concentrated in transmitter vesicles, where it replaces norepinephrine.It may also inhibit the release of granules by decreasing norepinephrine. Uses: Sympatholytics. Synonyms: Guanethidine monosulfate. Grade: >98%. CAS No. 645-43-2. Molecular formula: C10H24N4O4S. Mole weight: 296.39. | |
| Guanfacine | Guanfacine, a selective agonist of α2A receptor, is a sympatholytic drug to treat attention deficit hyperactivity disorder (ADHD) and hypertension. It lowers both systolic and diastolic blood pressure due to activating the central nervous system α2A norep. Uses: Adrenergic alpha-2 receptor agonists. Synonyms: N-(diaminomethylidene)-2-(2,6-dichlorophenyl)acetamide BS 100 141 BS-100-141 BS100141 Estulic Guanfacine Guanfacine Hydrochloride Guanfacine Monohydrochloride Hydrochloride, Guanfacine Lon798 Monohydrochloride, Guanfacine Tenex. Grade: > 95%. CAS No. 29110-47-2. Molecular formula: C9H9Cl2N3O. Mole weight: 246.10. | |
| Guanfacine hydrochloride | Guanfacine, a selective agonist of α2A receptor, is a sympatholytic drug to treat attention deficit hyperactivity disorder (ADHD) and hypertension. It lowers both systolic and diastolic blood pressure. Synonyms: BS 100-141; Tenex; Estulic; Guanfacine HCl; N-Carbamimidoyl-2-(2,6-dichlorophenyl)acetamide hydrochloride; N-(Aminoiminomethyl)-2,6-dichlorobenzeneacetamide hydrochloride; N-Amidino-2-(2,6-dichlorophenyl)acetamide hydrochloride; Benzeneacetamide, N-(aminoiminomethyl)-2,6-dichloro-, hydrochloride (1:1). Grade: 95%. CAS No. 29110-48-3. Molecular formula: C9H10Cl3N3O. Mole weight: 282.56. | |
| Guanfacine Methyl Ester Impurity | Guanfacine Methyl Ester Impurity is intermediate in the preparation of Guanfacine. Synonyms: 2,6-Dichlorobenzeneacetic acid methyl ester; Methyl 2,6-dichlorophenylacetate; Methyl 2-(2,6-Dichlorophenyl)Ethanoate; St5406080. Grade: > 95%. CAS No. 54551-83-6. Molecular formula: C9H8Cl2O2. Mole weight: 219.07. | |
| Guanidinoethyl sulfonate | Guanidinoethyl sulfonate is a natural guanidine-taurine analog derived from taurine. It acts as a competitive glycine receptor antagonist. Synonyms: NSC 667063; Taurocyamine; 2-[(aminoiminomethyl)amino]-ethanesulfonic acid. Grade: ≥95%. CAS No. 543-18-0. Molecular formula: C3H9N3O3S. Mole weight: 167.2. | |
| Guanine | Guanine is a purine base which is the component of nucleotides occurring in nucleic acids. Synonyms: 2-Amino-1,9-dihydro-6H-purin-6-one; 2-Amino-6-hydroxy-1H-purine; 2-Amino-6-hydroxypurine; 2-Aminohypoxanthine; 9H-Guanine; 2-Amino-hypoxanthine; Acyclovir Impurity B; Guanin. Grade: ≥98%. CAS No. 73-40-5. Molecular formula: C5H5N5O. Mole weight: 151.13. | |
| Guanine-13C2-15N | Guanine-13C2-15N is a labelled Guanine. Guanine is a purine base participating in the biosynthesis of DNA and RNA. Synonyms: 2-Amino-1,9-dihydro-6H-purin-6-one; 2-Amino-6-hydroxy-1H-purine-13C2,15N; 2-Amino-6-hydroxypurine-13C2,15N; 2-Aminohypoxanthine-13C2,15N; 9H-Guanine-13C2,15N; 2-Amino-hypoxanthine-13C2,15N. Grade: > 95%. Molecular formula: C3[13C]2H5N4[15N]O. Mole weight: 154.10. | |
| Guanine related compound 1 | Guanine-related compound 1, a revolutionary biomedical tool, intricately manipulates the pervasive DNA and RNA synthesis pathways, rendering its indispensability in studyting an extensive array of afflictions. Grade: > 95%. Molecular formula: C11H15N5O3. Mole weight: 265.27. | |
| Guanine related compound 2 | Guanine related compound 2 is a biomedicine utilized in the research of various diseases. It functions by targeting specific molecular pathways related to guanine metabolism. This compound plays a crucial role in suppressing the growth of certain malignant tumor cells. Grade: > 95%. Molecular formula: C11H15N5O3. Mole weight: 265.27. | |
| Guanine related compound 3 | Guanine related compound 3 is an integral biomedical entity used in studying diverse maladies associated with guanine metabolism. Manifesting itself as a pivotal precursor for guanine nucleotides' synthetic processes, it assumes a cardinal role in the synthesis of DNA and RNA. Grade: > 95%. Molecular formula: C9H13N5O2. Mole weight: 223.24. | |
| Guanoclor | Guanoclor, also known as guanochlor, is an antihypertensive drug. Synonyms: Vatensol; Guanochlor; guanochlorine; NSC-108163; 2-(2-(2,6-dichlorophenoxy)ethyl)hydrazine-1-carboximidamide. Grade: 95%. CAS No. 5001-32-1. Molecular formula: C9H12Cl2N4O. Mole weight: 263.12. | |
| Guanosine 2',3'-Cyclic Monophosphate Triethylamine Salt | A cyclic nucleotide with non-selective neoplasm inhibitory effects. It inhibited the growth of 4 tumorigenic cell lines, strain L, HeLa, HEp-2, and F1 amnion and nonmalignant cell lines. It also has analgesic activity. Synonyms: Guanosine Cyclic 2',3'-(Hydrogen Phosphate) N,N-Diethylethanamine. Grade: 97%. CAS No. 73647-09-3. Molecular formula: C16H27N6O7P. Mole weight: 446.4. | |
| Guanosine-2'(3')-monophosphate disodium salt | Guanosine-2'(3')-monophosphate disodium salt, a remarkable biomedicine product, emerges as a potent weapon in combating a myriad of multifarious diseases. Its unrivaled prowess as a precursor to cyclic guanosine monophosphate, an integral second messenger orchestrating intricate cellular signaling pathways, renders it indispensable. Synonyms: Guanylic acid disodium salt; Guanosine 2'-3'-monophosphate disodium salt mixed Isomers; 2'-Guanylic acid, disodium salt; (2R,3R,4R,5R)-2-(2-amino-6-hydroxypurin-9-yl)-4-hydroxy-5-(hydroxymethyl)oxola n-3-yl dihydrogen phosphate, sodium salt, sodium salt. Grade: 98%. CAS No. 70347-42-1. Molecular formula: C10H12N5O8PNa2. Mole weight: 407.18. | |
| Guanosine-2',5'-bisphosphate | Guanosine-2',5'-bisphosphate is a paramount molecule in the biomedical sector, exhibiting its indispensability by serving as a substrate for enzymes participating in signal transduction pathways, thereby playing a seminal role in vital cellular processes. This multifunctional product finds extensive application in scientific investigations pertaining to G-proteins, kinases and ion channels, enabling researchers to gain deeper insights into cellular functions. Synonyms: Guanosine-2',5'-bisphosphate, Triethylammonium salt. Grade: ≥ 95 % by HPLC. Molecular formula: C10H15N5O11P2(free acid). Mole weight: 443.20 (free acid). | |
| Guanosine, 2'-?O-?[bis(4-?methoxyphenyl)?phenylmethyl]?-?3'-?O-?methyl-?N-?(2-?methyl-?1-?oxopropyl)?- | Guanosine, bearing the structural nomenclature "2'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-methyl-N-(2-methyl-1-oxopropyl)-", aids to the research of select neoplasms. It exerts its anticarcinogenic effects by functioning as a formidable inhibitor of enzymes that mediate malignant tumor progression and expansion. CAS No. 2241581-18-8. Molecular formula: C36H39N5O8. Mole weight: 669.72. | |
| Guanosine, 3',?4'-?didehydro-?3'-?deoxy- | Guanosine, 3',4'-didehydro-3'-deoxy- is an influential compound extensively utilized in the realm of biomedical sciences, frequently examined alongside nucleotide analogs and antiviral compounds, aiding in studying diverse viral afflictions. Synonyms: 3',4'-Didehydro-3'-deoxyguanosine; 6H-Purin-6-one, 2-amino-9-[(2R,3R)-2,3-dihydro-3-hydroxy-5-(hydroxymethyl)-2-furanyl]-1,9-dihydro-. CAS No. 1262202-31-2. Molecular formula: C10H11N5O4. Mole weight: 265.23. | |
| Guanosine 3',5'-bisdiphosphate lithium salt | Regulates gene transcription; inhibits the synthesis of tRNA and rRNA. Synonyms: Guanosine 3'-(trihydrogen diphosphate), 5'-(trihydrogen diphosphate), lithium salt; Guanosine 5'-diphosphate 3'-diphosphate lithium salt; ppGpp lithium salt; Guanosine 3',5'-bis(trihydrogen diphosphate) lithium salt; Guanosine 3'-diphosphate 5'-diphosphate lithium salt. CAS No. 57421-51-9. Molecular formula: C10H17N5O17P4·xLi. Mole weight: 603.16 (free acid). | |
| Guanosine-3',5'-bisphosphate | Guanosine-3',5'-bisphosphate is a robust and indispensable molecule within the biomedical sector is adeptly modulates intricate cellular proceedings. Exhibiting the prowess of a secondary messenger, this compound intricately navigates intracellular signaling pathways is adroitly orchestrating a symphony of diverse biological functionalities encompassing gene expression, protein synthesis and cellular proliferation. Synonyms: (pGp); Guanosine-3',5'-bisphosphate, Triethylammonium salt. Grade: ≥ 95 % by HPLC. Molecular formula: C10H15N5O11P2(free acid). Mole weight: 443.20 (free acid). | |
| Guanosine 3',5'-cyclic monophosphate | Cyclic guanosine monophosphate (Cyclic GMP) is a guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'-and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. 3',5'-cyclic GMP is a 3',5'-cyclic purine nucleotide in which the purine nucleobase is specified as guanidine. It has a role as a plant metabolite, a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a guanyl ribonucleotide and a 3',5'-cyclic purine nucleotide. It is a conjugate acid of a 3',5'-cyclic GMP(1-). Synonyms: 3:5-CGMP; D-Guanosine 3',5'-cyclic monophosphate; 3',5'-cyclic GMP; 2-Amino-6-oxo-6,9-dihydro-1H-purine 3-oxide; guanine-3-N-oxide; 2-Amino-1,7-dihydro-6H-purin-6-one 3-oxide; Cyclic guanosine monophosphate. Grade: ≥98%. CAS No. 7665-99-8. Molecular formula: C10H12N5O7P. Mole weight: 345.21. | |
| Guanosine 3,5-cyclic monophosphate-15N5 | Guanosine 3,5-cyclic monophosphate-15N5 is a labelled analogue of Guanosine 3,5-cyclic monophosphate. Grade: > 95%. Molecular formula: C10H12[15N]5O7P. Mole weight: 350.18. | |
| Guanosine 3',5'-Cyclic Monophosphate Monoammonium Salt | Guanosine 3',5'-Cyclic Monophosphate Monoammonium Salt is the salt form of Guanosine 3',5'-Cyclic Monophosphate, which is an intracellular second messenger which are involved in the transduction of a diverse array of stimuli, mediating metabolic and growth regulation. Molecular formula: C10H15N6O7P. Mole weight: 362.24. | |
| Guanosine 3',5'-Diphosphate Tetralithium Salt | Guanosine 3',5'-Diphosphate Tetralithium Salt is a drug transporter on the arachnoid barrier cells that contribute to blood-cerebrospinal fluid barrier. Synonyms: Guanosine 3',5'-Bis(dihydrogen Phosphate) Tetralithium Salt; 3',5'-Diphosphoguanosine Tetralithium Salt. CAS No. 55612-39-0. Molecular formula: C10H11Li4N5O11P2. Mole weight: 466.93. | |
| Guanosine-3',5'-pentaphosphate Lithium salt | Guanosine-3',5'-pentaphosphate Lithium salt, a biochemical compound applied in biomedicine, facilitates examination of bacterial signaling pathways, their function in virulence, antibiotic resistance and biofilm formation, as well as the identification of potent antibacterial agents for enterococci and the role of guanosine pentaphosphate (pppGpp) in bacterial pathogenesis and stress response. This compound unleashes a veritable treasure trove of knowledge for our understanding of bacterial physiology-related phenomena. Synonyms: (pppGpp); Guanosine-3'-diphosphate, 5'-triphosphate, Lithium salt; Guanosine 5'-(tetrahydrogen triphosphate) 3'-(trihydrogen diphosphate) Lithium salt; Guanosine pentaphosphate Lithium salt. Grade: ≥85% by HPLC. Molecular formula: C10H18N5O20P5 (free acid). Mole weight: 683.14 (free acid). | |
| Guanosine, 3'-?amino-?3'-?deoxy-?2'-?O-?methyl-(9CI) | Guanosine 3'-amino-3'-deoxy-2'-O-methyl (9CI) is a nucleoside with structural similarity to established antiviral agents. Its potential in therapy against viral infections such as herpes and varicella-zoster virus as well as certain types of cancer make it a subject of ongoing research. Its mode of action lies in impeding the synthesis of viral RNA and DNA, thereby thwarting the propagation of viral and cancerous cells alike. CAS No. 847649-20-1. Molecular formula: C11H16N6O4. Mole weight: 296.28. | |
| Guanosine, 3'-?deoxy-?2'-?O-?(1,?1-?difluoro-?2-?methoxyethyl)?-?3'-?[[(4-?methoxyphenyl)?diphenylmethyl]?amino]?-?N-?(2-?methyl-?1-?oxopropyl)?-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Guanosine, 3'-deoxy-2'-O-(1,1-difluoro-2-methoxyethyl)-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-N-(2-methyl-1-oxopropyl), 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a chemical utilized in RNA synthesis. It serves as a modified nucleoside to improve the binding affinity of RNA with therapeutic drugs in treating viral diseases such as HIV and hepatitis C. Synonyms: ((2S,3R,4R,5R)-5-(6-benzamido-2-isobutyramido-9H-purin-9-yl)-4-(1,1-difluoro-2-methoxyethoxy)-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299279-99-3. Molecular formula: C46H57F2N8O8P. Mole weight: 918.96. | |
| Guanosine, 3'-?deoxy-?2'-?O-?(2-?methoxyethyl)?-?3'-?[[(4-?methoxyphenyl)?diphenylmethyl]?amino]?-?N-?(2-?methyl-?1-?oxopropyl)?- | Guanosine, 3'-deoxy-2'-O-(2-methoxyethyl)-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-N-(2-methyl-1-oxopropyl) is an exquisite biomedical compound, renowned for its antiviral prowess. It diligently aids to study pernicious viral infections such as hepatitis C and herpes simplex. CAS No. 2299278-41-2. Molecular formula: C37H42N6O7. Mole weight: 682.77. | |
| Guanosine, 3'-?deoxy-?2'-?O-?(2-?methoxyethyl)?-?3'-?[[(4-?methoxyphenyl)?diphenylmethyl]?amino]?-?N-?(2-?methyl-?1-?oxopropyl)?-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Guanosine, 3'-deoxy-2'-O-(2-methoxyethyl)-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-N-(2-methyl-1-oxopropyl)-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is an indispensable compound employed extensively in the realm of biomedical exploration, specifically in nucleic acid synthesis. This remarkable compound acts as a modulated foundational unit in the paradigm of solid-phase DNA synthesis, consequently enabling the assimilation of aforementioned guanosine variant into the very fabric of DNA filaments. By virtue of its distinctive phosphoramidite structure, this exemplary specimen facilitates focused inquiry into precise DNA modifications. Synonyms: ((2S,3R,4R,5R)-5-(6-benzamido-2-isobutyramido-9H-purin-9-yl)-4-(2-methoxyethoxy)-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299278-14-9. Molecular formula: C46H59N8O8P. Mole weight: 882.98. | |
| Guanosine, 3'-?deoxy-?2'-?O-?ethyl-?3'-?[[(4-?methoxyphenyl)?diphenylmethyl]?amino]?-?N-?(2-?methyl-?1-?oxopropyl)?-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Guanosine, 3'-deoxy-2'-O-ethyl-3'-[[(4-methoxyphenyl)?diphenylmethyl]?amino]?-N-(2-methyl-1-oxopropyl)?-, 5'-[2-cyanoethyl N,?N-bis(1-methylethyl)?phosphoramidite] is a pivotal constituent, emanates as a linchpin in the explicit domain of nucleic acid synthesis, intently within DNA and RNA exploration. It confers enhanced prospects for manufacturing modified nucleotides as well as derivatives pertaining to nucleic acids, necessitated for investigations encompassing the structural, functional and behavioral attributes pertinent to DNA and RNA molecules, rendering significant insights. Synonyms: 2-cyanoethyl (((2S,3R,4R,5R)-4-ethoxy-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl) diisopropylphosphoramidite. CAS No. 2299279-11-9. Molecular formula: C45H57N8O7P. Mole weight: 852.96. | |
| Guanosine, 3'-?deoxy-?3'-?[[(4-?methoxyphenyl)?diphenylmethyl]?amino]?-?N-?(2-?methyl-?1-?oxopropyl)?-?2'-?O-?2-?propen-?1-?yl-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Guanosine, 3'-deoxy-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-N-(2-methyl-1-oxopropyl)-2'-O-2-propen-1-yl-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] serves as an indispensable compound within the biomedical sector, utilized for the synthesis of modified nucleotides. Its paramount importance lies in its significant contribution to the advancement of nucleic acid-based therapeutics, including antisense oligonucleotides, siRNAs and aptamers. Synonyms: ((2S,3R,4R,5R)-4-(allyloxy)-5-(6-benzamido-2-isobutyramido-9H-purin-9-yl)-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299283-17-1. Molecular formula: C46H57N8O7P. Mole weight: 864.97. | |
| Guanosine 3'-(dihydrogen phosphate) | Guanosine 3'-(dihydrogen phosphate) serves as a fundamental nucleotide extensively employed within the biomedical sphere. Its indispensability stems from its involvement in the intricate synthesis of DNA and RNA, thereby governing gene expression and protein synthesis. Synonyms: Guanosine 3'-monophosphate; guanosine 3'-phosphate. CAS No. 117-68-0. Molecular formula: C10H14N5O8P. Mole weight: 363.22. | |
| Guanosine 3'-diphosphate 5'-triphosphate | Guanosine 3'-diphosphate 5'-triphosphate is a pivotal molecule entwined in signal transduction and protein synthesis, emerging as an indispensable compound. It exert its prowess as an enthusiastic bestower of energy during translation, while adroitly orchestrating the activity of G-proteins. It assumes a role in unraveling the enigmatic dynamics of enzyme kinetics, nucleotide metabolism and the meticulous dissection of ailments synonymous to G-protein signaling cascades. Synonyms: Guanosine-3',5'-pentaphosphate; Guanosine pentaphosphate; pppGpp; Guanosine 5'-(tetrahydrogen triphosphate) 3'-(trihydrogen diphosphate); ((2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-hydroxy-3-((hydroxy(phosphonooxy)phosphoryl)oxy)tetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate; 5'-Triphosphoguanosine 3'-diphosphate. Grade: ≥95%. CAS No. 38918-96-6. Molecular formula: C10H18N5O20P5. Mole weight: 683.14. | |
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