BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Lumiracoxib | Lumiracoxib is a novel, selective COX-2 inhibitor. Uses: Cyclooxygenase 2 inhibitors. Synonyms: CGS-35189; CGS 35189; CGS35189; COX-189; COX189; COX 189; Lumiracoxib; trade name: Prexige. Grades: > 95%. CAS No. 220991-20-8. Molecular formula: C15H13ClFNO2. Mole weight: 293.72. |  |
| Lurbinectedin | Lurbinectedin, also known as PM01183, is a synthetic tetrahydropyrrolo [4, 3, 2-de]quinolin-8(1H)-one alkaloid analogue with potential antineoplastic activity. DNA minor groove-binding agent PM01183 covalently binds to residues lying in the minor groove of DNA, which may result in delayed progression through S phase, cell cycle arrest in the G2/M phase and cell death. Synonyms: PM-01183; PM 01183; PM01183. Lurbinectedin. CAS No. 497871-47-3. Molecular formula: C41H44N4O10S. Mole weight: 784.881. | |
| Lusutrombopag | Lusutrombopag is an orally bioavailable, small molecule thrombopoietin (TPO) receptor agonist. It acts selectively on the human TPO receptor and activates signal transduction pathways and thereby increases platelet levels. It was developed by Shionogi for chronic liver disease (CLD) patients with thrombocytopenia prior to elective invasive surgery. It has been listed. Uses: Lusutrombopag was used for chronic liver disease (cld) patients with thrombocytopenia prior to elective invasive surgery. Synonyms: S-888711; S 888711; S888711; (E)-3-[2,6-dichloro-4-[[4-[3-[(1S)-1-hexoxyethyl]-2-methoxyphenyl]-1,3-thiazol-2-yl]carbamoyl]phenyl]-2-methylprop-2-enoic acid. Grades: >98%. CAS No. 1110766-97-6. Molecular formula: C29H32Cl2N2O5S. Mole weight: 591.54. | |
| Lvguidingan | Lvguidingan is an antiepileptic drug. Synonyms: Anticonvulsant 7903; N-(Butan-2-yl)-3-(3,4-dichlorophenyl)prop-2-enamide; 3,4-Dichlorophenyl propenylisobutylamide; 3,4-Dichlorophenylpropenoyl isobutylamide. CAS No. 82351-05-1. Molecular formula: C13H15Cl2NO. Mole weight: 272.169. | |
| L-Vinylglycine | L-Vinylglycine is a non-proteinogenic L-alpha-amino acid and an inhibitor of aspartate aminotransferase. Synonyms: (S)-2-Aminobut-3-enoic acid; Vinylglycine; 3-Butenoic acid, 2-amino-, (2S)-; (2S)-2-aminobut-3-enoic acid. Grades: 95%. CAS No. 70982-53-5. Molecular formula: C4H7NO2. Mole weight: 101.105. | |
| LX-4211 | LX-4211 is a potent dual SGLT2/1 inhibitor; Antidiabetic agents. Uses: Sodium-glucose transporter 2 inhibitors. Synonyms: LX4211; LX-4211; LX 4211; Sotagliflozin. Grades: >98%. CAS No. 1018899-04-1. Molecular formula: C21H25ClO5S. Mole weight: 424.94. | |
| LY-2562175 | LY2562175 is a potent and selective FXR agonist in vitro. It has robust lipid modulating properties, lowering LDL and triglycerides while raising HDL in preclinical species. It was developed by Eli Lilly and Company and in clinic phase 1 trials with no progress. Uses: Ly2562175 has robust lipid modulating properties, lowering ldl and triglycerides while raising hdl in preclinical species. Synonyms: LY2562175; LY 2562175; LY-2562175;6-(4-((5-Cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)piperidin-1-yl)-1-methyl-1H-indole-3-carboxylic acid. Grades: >98%. CAS No. 1103500-20-4. Molecular formula: C28H27Cl2N3O4. Mole weight: 540.44. | |
| LY2606368 | LY2606368 is a potent and selective ATP competitive inhibitor(IC50=1.5 nM in SW1990 cell) of the Chk1 protein kinase. Synonyms: LY-2606368; LY 2606368. Grades: >98%. CAS No. 1234015-52-1. Molecular formula: C18H19N7O2. Mole weight: 365.397. | |
| LY2955303 | LY 2955303, is a potent and selective retinoic acid receptor gamma (RARγ) antagonist with a Ki of 1.09 nM. Uses: Osteoarthritis pain. Synonyms: 4-[5-[3,5-Bis(1,1-dimethylethyl)phenyl]-1-[4-[(4-methyl-1-piperazinyl)carbonyl]phenyl]-1H-pyrazol-3-yl]benzoic Acid; LY-2955303; LY2955303; 4-(5-[3,5-Bis(2-methyl-2-propanyl)phenyl]-1-{4-[(4-methyl-1-piperazinyl)carbonyl]phenyl}-1H-pyrazol-3-yl)benzoic acid; Benzoic acid, 4-[5-[3,5-bis(1,1-dimethylethyl)phenyl]-1-[4-[(4-methyl-1-piperazinyl)carbonyl]phenyl]-1H-pyrazol-3-yl]-. Grades: 98%. CAS No. 1433497-19-8. Molecular formula: C36H42N4O3. Mole weight: 578.74. | |
| LY3009120 | LY03009120 is a potent pan-Raf inhibitor with IC50 of 44 nM, 31-47 nM, and 42 nM for A-raf, B-Raf, and C-Raf in A375 cells, respectively. Phase 1. Synonyms: LY3009120; LY-3009120; LY 3009120; DP4978; DP 4978; DP-4978. Grades: 98%. CAS No. 1454682-72-4. Molecular formula: C23H29FN6O. Mole weight: 424.51. | |
| (-)-LY-338979 | (-)-LY-338979 is one of pemetrexed metabolites. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: (S)-2-(4-(2-((R)-2-amino-4,6-dioxo-4,5,6,7-tetrahydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioic acid; (4-(2-((R)-2-amino-4,6-dioxo-4,5,6,7-tetrahydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoyl)-L-glutamic acid; N-(4-{2-[(5R)-2-Amino-4,6-dioxo-4,5,6,7-tetrahydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl]ethyl}benzoyl)-L-glutamic acid; L-Glutamic acid, N-[4-[2-[(5R)-2-amino-4,5,6,7-tetrahydro-4,6-dioxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl]ethyl]benzoyl]-. Molecular formula: C20H21N5O7. Mole weight: 443.41. | |
| (+)-LY-338979 | (+)-LY-338979 is one of pemetrexed metabolites. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: (S)-2-(4-(2-((S)-2-amino-4,6-dioxo-4,5,6,7-tetrahydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioic acid; (4-(2-((S)-2-amino-4,6-dioxo-4,5,6,7-tetrahydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoyl)-L-glutamic acid; N-(4-{2-[(5S)-2-Amino-4,6-dioxo-4,5,6,7-tetrahydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl]ethyl}benzoyl)-L-glutamic acid; L-Glutamic acid, N-[4-[2-[(5S)-2-amino-4,5,6,7-tetrahydro-4,6-dioxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl]ethyl]benzoyl]-. Molecular formula: C20H21N5O7. Mole weight: 443.41. | |
| LY-338979 Dimethyl Ester | LY-338979 dimethyl ester is one of pemetrexed metabolites. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: Dimethyl N-{4-[2-(2-amino-4,6-dioxo-4,5,6,7-tetrahydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}-L-glutamate; N-[4-[2-(2-Amino-4,5,6,7-tetrahydro-4,6-dioxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid 1,5-Dimethyl Ester; L-Glutamic acid, N-[4-[2-(2-amino-4,5,6,7-tetrahydro-4,6-dioxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-, dimethyl ester. Grades: ≥95%. CAS No. 1320346-45-9. Molecular formula: C22H25N5O7. Mole weight: 471.46. | |
| LY 368962 Dimethyl Ester | LY 368962 dimethyl ester is one of pemetrexed metabolites. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: Dimethyl N-{4-[3-(2,6-diamino-4-oxo-1,4-dihydro-5-pyrimidinyl)-3-oxopropyl]benzoyl}-L-glutamate; L-Glutamic acid, N-[4-[3-(2,6-diamino-1,4-dihydro-4-oxo-5-pyrimidinyl)-3-oxopropyl]benzoyl]-, dimethyl ester; N-[4-[3-(2,6-Diamino-1,4-dihydro-4-oxo-5-pyrimidinyl)-3-oxopropyl]benzoyl]-L-glutamic Acid Dimethyl Ester; Dimethyl (4-(3-(2,6-diamino-4-oxo-1,4-dihydropyrimidin-5-yl)-3-oxopropyl)benzoyl)-L-glutamate. Grades: 98%. CAS No. 1798887-66-7. Molecular formula: C21H25N5O7. Mole weight: 459.45. | |
| LY-900009 | LY-900009 is a small-molecule inhibitor of Notch signalling with IC50 value of 0.27 nM via selective inhibition of the γ-secretase protein. LY-900009 was developed as a candidate therapeutic drug against AD (IDENTITY trial), which failed in phase III trials. Uses: Gamma secretase inhibitors and modulators. Synonyms: LY900009; LY-900009; LY 900009; (2S)-2-hydroxy-3-methyl-N-[(2S)-1-[[(7S)-5-methyl-6-oxo-7H-benzo[d][1]benzazepin-7-yl]amino]-1-oxopropan-2-yl]butanamide. Grades: >98%. CAS No. 209984-68-9. Molecular formula: C23H27N3O4. Mole weight: 409.486. | |
| Lycoramine | Dihydro Galantamine is one of the minor alkaloids of Lycoris radiat. It is also an analog of Galanthamine. Synonyms: Galantamine Impurity C; (4aS,6S,8aR)-4a,5,7,8,9,10,11,12-Octahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol; Dihydrogalanthamine; 1,2-Dihydrogalanthamine; (8aS)-3-Methoxy-5,6,7,8,9,10,11,12-octahydro-11-methyl-4aαH-benzofuro[3a,3,2-ef][2]. Grades: > 95%. CAS No. 21133-52-8. Molecular formula: C17H23NO3. Mole weight: 289.38. | |
| Lys05 | Lys05, a water-soluble salt of Lys01, is a selective and orally available inhibitor of AXL and c-Met with IC50 values of 7 nM and 12 nM, respectively, resulting in sustained inhibition of autophagy and tumor growth. Synonyms: LYS-05 HCl; LYS05; LYS-05; Lys01 trihydrochloride; Lys01 3HCl; N-(7-chloroquinolin-4-yl)-N'-[2-[(7-chloroquinolin-4-yl)amino]ethyl]-N'-methylethane-1,2-diamine trihydrochloride. CAS No. 1391426-24-6. Molecular formula: C23H26Cl5N5. Mole weight: 549.75. | |
| Lys(Ac)-Octreotide | Lys(Ac)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Uses: Radiopharmaceuticals. Synonyms: Lys(Ac) 5 Octreotide; D-phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl(acetyl)-L-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7); L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-N6-acetyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2?7)-disulfide; D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-N6-acetyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-L-cysteinamide cyclic (2?7)-disulfide; L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-N6-acetyl-L-lysyl-L-threonyl-N-[2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2?7)-disulfide, [R-(R*,R*)]-. Grades: ≥95%. CAS No. 173606-11-6. Molecular formula: C51H68N10O11S2. Mole weight: 1061.28. | |
| Lysine-methotrexate | Lysine-methotrexate is one of Methotrexate derivatives. Methotrexate is a Folic Acid antagonist, used as an antineoplastic and antirheumatic. Synonyms: (4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzoyl)-L-lysine; N2-[4-[[ (2, 4-diamino-6-pteridinyl) methyl]methylamino]benzoyl]-L-Lysine; N(alpha)-(p-Amino-4-deoxy-N(10)-methylpteroyl)lysine. Grades: 98%. CAS No. 80407-56-3. Molecular formula: C21H27N9O3. Mole weight: 453.50. | |
| Lysipressin | Lysipressin Acetate is a lysine vasopressin, which retains water in the body and constricts blood vessels. Synonyms: Lys(8)-Vasopressin; Lys(8)-AVP; H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2 (Disulfide bridge: Cys1-Cys6); L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-lysyl-glycinamide (1->6)-disulfide; Vasopressin, 8-L-lysine-; 1,2-Dithia-5,8,11,14,17-pentaazacycloeicosane-10-propionamide, 19-amino-4-[2-[[5-amino-1-[ (carbamoylmethyl) carbamoyl]pentyl]carbamoyl]-1-pyrrolidinylcarbonyl]-13-benzyl-7- (carbamoylmethyl) -16-p-hydroxybenzyl-6, 9, 12, 15, 18-pentaoxo-; 8-L-Lysinevasopressin; 3-(Phenylalanine)-8-lysine oxytocin; 8-L-Lysine vasopressin; L-Lysine vasopressin; [8-Lysine]vasopressin; Diapid; Lysine pitressin; Lysine vasopressin; Lysine-ADH; Lysylvasopressin; Oxytocin, 3-(L-phenylalanine)-8-L-lysine-; Postacton; Syntopressin; Vasophysin; Vasopressin-8-lysine; Lysine-AVP. Grades: 98%. CAS No. 50-57-7. Molecular formula: C46H65N13O12S2. Mole weight: 1056.22. | |
| Macitentan | Macitentan is an orally available dual endothelin receptor (ETR) antagonist with potential antihypertensive and antineoplastic activity. Uses: Endothelin a receptor antagonists. Synonyms: ACT-064992; ACT064992; ACT 064992. Grades: > 95%. CAS No. 441798-33-0. Molecular formula: C19H20Br2N6O4S. Mole weight: 588.275. | |
| Macitentan Hydroxy amine Impurity | It is an impurity of Macitentan, a dual orally active endothelin receptor antagonist used for pulmonary arterial hypertension. Synonyms: Ethanol, 2-((6-amino-5-(4-bromophenyl)pyrimidin-4-yl)oxy); 2-((6-amino-5-(4-bromophenyl)pyrimidin-4-yl)oxy)ethan-1-ol. CAS No. 2211059-05-9. Molecular formula: C12H12BrN3O2. Mole weight: 310.15. | |
| Macitentan Impurity 1 | An impurity of Macitentan, a dual orally active endothelin receptor antagonist used for pulmonary arterial hypertension. Synonyms: Despropylaminosulfonyl Macitentan; 5-(4-Bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-4-pyrimidinamine; ACT 080803. Grades: > 95%. CAS No. 1433875-21-8. Molecular formula: C16H13Br2N5O2. Mole weight: 467.11. | |
| Macitentan Pyrimidine Dimer | It is an impurity of Macitentan, a dual orally active endothelin receptor antagonist used for pulmonary arterial hypertension. Synonyms: Macitentan Dimer; O-Desbromo-pyrimidinyl O-[6-N-(N'-propyl)sulfamido-5-(4-bromophenyl)pyrimidin-4-yl] Macitentan; Macitentan Impurity 06; 1,2-bis((5-(4-bromophenyl)-6-[2-(5-bromopyrimidin-2-yl)oxy)ethane. CAS No. 2089065-77-8. Molecular formula: C28H32Br2N8O6S2. Mole weight: 800.54. | |
| MAK683 | MAK683 is an inhibitor of embryonic ectoderm development protein (EED) with potential antineoplastic activity. MAK683 binds to the domain of EED that interacts with trimethylated lysine 27 on histone 3 (H3K27me3), leading to a conformational change in the EED H3K27me3-binding pocket and preventing the interaction of EED with the histone methyltransferase enhancer zeste homolog 2 (EZH2). MAK683 is undergoing phase II clinical trials for the identification of antitumor activity. Synonyms: MAK-683; MAK 683; MAK683; EED inhibitor-1; N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-8-(2-methylpyridin-3-yl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine. Grades: 98%. CAS No. 1951408-58-4. Molecular formula: C20H17FN6O. Mole weight: 376.395. | |
| Mapenterol | Mapenterol is a related drug of Clenbuterol, which is used as a tocolytic, bronchodilator, and heart tonics in human and veterinary medicine. Synonyms: 4-Amino-3-chloro-α-[[(1,1-dimethylpropyl)amino]methyl]-5-(trifluoromethyl)benzenemethanol; Benzenemethanol, 4-amino-3-chloro-α-[[(1,1-dimethylpropyl)amino]methyl]-5-(trifluoromethyl)-; 1-[4-Amino-3-chloro-5-(trifluoromethyl)phenyl]-2-[(2-methyl-2-butanyl)amino]ethanol. CAS No. 95656-68-1. Molecular formula: C14H20ClF3N2O. Mole weight: 324.77. | |
| Maraviroc | Maraviroc is a selective CCR5 antagonist. Synonyms: Maraviroc; Selzentry; Celsentri; UK-427857; UK-427,857; Pfizer Brand of maraviroc; Selzentry; UK-427,857; UK-427857; 4,4-Difluoro-N-[(1S)-3-[(3-exo)-3-[3-methyl-5-(1-methylethyl-d6)-4H-1,2,4-triazol-4-yl]-8-azabicyclo[3.2.1]oct-8-yl]-1-phenylpropyl]cyclohexanecarboxamide; UK 427857-d6. Grades: 0.9995. CAS No. 376348-65-1. Molecular formula: C29H41F2N5O. Mole weight: 513.67. | |
| marinobufagenin | Marinobufagenin (marinobufagin) is a cardiotonic bufadienolide steroid secreted by the toad Bufo rubescens and other related species such as Bufo marinus. It is a vasoconstrictor with effects similar to digitalis. Uses: Enzyme inhibitors; vasoconstrictor agents. Synonyms: Marinobufagin; (3beta,5beta,14alpha,15beta)-3,5-dihydroxy-14,15-epoxybufa-20,22-dienolide; NSC-234205. Grades: ≥ 98.0%. CAS No. 470-42-8. Molecular formula: C24H32O5. Mole weight: 400.52. | |
| MART-1 (26-35) human | MART-1 (26-35), an immunodominant antigen from melanocyte/melanoma (Melan-A/MART) protein, is amino acid residue 26 to 35 of MART-1 protein. Synonyms: Melanoma antigen recognized by T-cells 1 (26-35); MART-1(26-35)(A27L) peptide; Melan-A (26-35); H-Glu-Ala-Ala-Gly-Ile-Gly-Ile-Leu-Thr-Val-OH; L-alpha-glutamyl-L-alanyl-L-alanyl-glycyl-L-isoleucyl-glycyl-L-isoleucyl-L-leucyl-L-threonyl-L-valine. Grades: 98%. CAS No. 156251-01-3. Molecular formula: C42H74N10O14. Mole weight: 943.09. | |
| MAT2A-IN-9 | MAT2A-IN-9 is a potent inhibitor of MAT2A (methionine adenosyltransferase 2A) and exhibits anti-tumor activity in MTAP-deleted PDX models. Synonyms: 4-amino-1-(2-chlorophenyl)-7-(trifluoro-methyl)pyrido[2,3-d]pyrimidin-2(1H)-one; GSK-4362676; IDE397. CAS No. 2439277-80-0. Molecular formula: C14H8ClF3N4O. Mole weight: 340.69. | |
| Mavacoxib | Mavacoxib, a pyrazol derivative, has been found to be a COX-2 Inhibitor that could be used in pain and inflammation therapy for dogs. Synonyms: Mavacoxib; PHA-739521; PHA739521; PHA 739521; PHA 739,521; PHA739,521; PHA-739,521; Mavacoxib. trade name Trocoxil; UNII-YFT7X7SR77; 4-[5-(4-fluorophenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide. Grades: 98%. CAS No. 170569-88-7. Molecular formula: C16H11F4N3O2S. Mole weight: 385.34. | |
| Maxacalcitol | Maxacalcitol is non-calcemic vitamin D3 analog and ligand of VDR-like receptors. Uses: Dermatologic agents. Synonyms: 22-Oxacalcitriol. Grades: >98%. CAS No. 103909-75-7. Molecular formula: C26H42O4. Mole weight: 418.61. | |
| Maxacalcitol Impurity B | Synonyms: MC 1292. Grades: > 95%. CAS No. 132071-85-3. Molecular formula: C26H42O4. Mole weight: 418.6. | |
| Maxacalcitol Intermediate | An intermediate of maxacalcitol, which is a derivative of vitamin D3. Maxacalcitol is a potential treatment of secondary hyperparathyroidism. Molecular formula: C38H68O5Si2. Mole weight: 661.127. | |
| MAZ51 | MAZ51 is an indolinone that blocks the ligand-induced autophosphorylation of VEGFR-3 by VEGF-C. It was shown to inhibit proliferation and induce apoptosis of tumor cell lines. Synonyms: (E)-3-((4-(dimethylamino)naphthalen-1-yl)methylene)indolin-2-one; 3-(4-Dimethylaminonaphthalen-1-ylmethylene)-1,3-dihydroindol-2-one; EX-A1914. Grades: ≥95%. CAS No. 163655-37-6. Molecular formula: C21H18N2O. Mole weight: 314.4. | |
| MBX-2982 | MBX-2982 is a potential first-in-class treatment for type 2 diabetes that targets G protein-coupled receptor 119 (GPR119), a receptor that interacts with bioactive lipids known to stimulate glucose-dependent insulin secretion. Preclinical data indicate that MBX-2982 is a potent selective orally-active GPR119 agonist that functions through a unique dual mechanism of action. First, it acts directly on the beta cell to increase insulin secretion. In addition, MBX-2982 stimulates release of the incretin GLP-1 from the gut. This dual action is unique and may offer improved glucose homeostasis over existing diabetes therapies, with potential for weight loss and improved islet health. Synonyms: Pyrimidine, MBX-2982; MBX 2982; MBX2982; SAR-260093; SAR260093; SAR 260093; 5-ethyl-2-(4-(4-((4-(1H-tetrazol-1-yl)phenoxy)methyl)-2-thiazolyl)-1-piperidinyl)-; 4-((4-(1H-tetrazol-1-yl)phenoxy)methyl)-2-(1-(5-ethylpyrimidin-2-yl)piperidin-4-yl)thiazole; B5TRY67L51. Grades: 98%. CAS No. 1037792-44-1. Molecular formula: C22H24N8OS. Mole weight: 448.549. | |
| MCP110 | MCP110 is a Ras/Raf-1 interaction inhibitor. The Ras signaling pathway is activated either by direct mutation of Ras or its effector B-Raf. MCP110 was shown to inhibit proliferation of tumor cells. Synonyms: MCP110; MCP-110; MCP 110; N-(4-(benzyloxy)-3-methoxybenzyl)-5-phenyl-N-(2-(pyridin-2-yl)ethyl)pentanamide. CAS No. 521310-51-0. Molecular formula: C33H36N2O3. Mole weight: 508.662. | |
| MDK34597 | MDK34597 is a PI3K inhibitor. Synonyms: MDK34597; MDK-34597; MDK 34597. PI3K inhibitor. PIK-inhibitors; 3-(8-Morpholin-4-yl-9-oxa-1,5,7-triaza-fluoren-6-yl)-phenylamine; 3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin-2-yl)aniline. CAS No. 371934-59-7. Molecular formula: C19H17N5O2. Mole weight: 347.378. | |
| MDK74978 | MDK74978 is a multi-kinase inhibitor. Synonyms: N- (2-Hydroxyethyl) -4- (6- (4- (trifluoromethoxy) phenylamino) pyrimidin-4-yl) benzamide; MDK74978; MDK-74978; MDK 74978. Multi-kinase inhibitor I. CAS No. 778274-97-8. Molecular formula: C20H17F3N4O3. Mole weight: 418.376. | |
| Medetomidine Impurity 10 | Cas No. 40234-75-2. | |
| Medetomidine Impurity 3 | Cas No. 1021949-47-2. | |
| Medetomidine Impurity 5 | Cas No. 138867-04-6. | |
| Medetomidine Impurity (Hydroxymedetomidine) | Cas No. 86347-12-8. | |
| Medroxyprogesterone 17-acetate | Medroxyprogesterone acetate is a progestin, a synthetic variant of the human hormone progesterone and a potent progesterone receptor agonist. Uses: Contraceptive agents, male. Synonyms: Baccatin III; Pregn-4-ene-3,20-dione, 17-(acetyloxy)-6-methyl-, (6α)-; (6α)-17-(Acetyloxy)-6-methylpregn-4-ene-3,20-dione; Pregn-4-ene-3,20-dione, 17-hydroxy-6α-methyl-, acetate; Progesterone, 17-hydroxy-6α-methyl-, acetate; 17α-Acetoxy-6α-methylpregn-4-ene-3,20-dione; 7α-Acetoxy-6α-methylprogesterone; 17α-Hydroxy-6α-methyl-4-pregnene-3,20-dione 17-acetate; 17α-Hydroxy-6α-methylpregn-4-ene-3,20-dione acetate; 17α-Hydroxy-6α-methylprogesterone acetate; 6α-Methyl-17-acetoxyprogesterone; 6α-Methyl-17R-hydroxyprogesterone acetate; 6α-Methyl-17α-acetoxy-Δ4-pregnene-3,20-dione; 6α-Methyl-17α-acetoxypregn-4-ene-3,20-dione; 6α-Methyl-17α-Hydroxy-4-pregnene-3,20-dione acetate; 6α-Methyl-17α-hydroxyprogesterone acetate; Amen; Metigestrona; MPA; Nadigest; Nidaxin; NSC 21171; NSC 26386; Oragest; Perlutex; Progevera; Repromap; Repromix; Sirprogen; U 8839; Veramix; Aragest; Clinovir; Depo-progestin; Depomedroxyprogesterone acetate; DMPA; Farlutal; Gestapuran; Hematrol; Indivina; Lutopolar; MAP; Medroprogesterone acetate; Medroxyprogesterone acetate; Meprate. Grades: >98%. CAS No. 71-58-9. Molecular formula: C24H34O4. Mole weight: 386.52. | |
| Medroxyprogesterone Acetate EP Impurity B | Medroxyprogesterone Acetate EP Impurity B is an impurity of Medroxyprogesterone Acetate, which is a progestin-type hormonal drug used in menopausal hormone therapy and progestogen-only birth control. Synonyms: Medroxyprogesterone Acetate Impurity B; 17-hydroxy-6α-methylpregn-4-ene-3,20-dione; Medroxyprogesterone; Medroxyprogesterone Acetate USP Related Compound B; Pregn-4-ene-3,20-dione, 17-hydroxy-6-methyl-, (6α)-; (6α)-17-Hydroxy-6-methylpregn-4-ene-3,20-dione; Pregn-4-ene-3,20-dione, 17-hydroxy-6α-methyl-; 17-Hydroxy-6α-methylpregn-4-ene-3,20-dione; 17-Hydroxy-6α-methylprogesterone; 17α-Hydroxy-6α-methylprogesterone; 6α-Methyl-17-hydroxyprogesterone; 6α-Methyl-17R-hydroxyprogesterone; 6α-Methyl-17α-hydroxypregn-4-ene-3,20-dione; 6α-Methyl-17α-hydroxyprogesterone; 6α-Methyl-4-pregnen-17α-ol-3,20-dione; Medoxyprogesterone; Medroxyprogesteron; NSC 27408; U 8840; Medroxy Progesterone; Medroxy Progesterone EP Impurity B. Grades: ≥95%. CAS No. 520-85-4. Molecular formula: C22H32O3. Mole weight: 344.49. | |
| Megestrol | Megestrol is an orally active progestogen. Megestrol is used in combinations as an oral contraceptive and antineoplastic agent. Uses: Antineoplastic agents, hormonal; progestational hormones, synthetic. Synonyms: 17-Hydroxy-6-methylpregna-4,6-diene-3,20-dione. Grades: > 95%. CAS No. 3562-63-8. Molecular formula: C22H30O3. Mole weight: 342.47. | |
| Melanotan I | A synthetic analogue of α-melanocyte stimulating hormone (α-MSH). Synonyms: Afamelanotide acetate; (Nle4,D-Phe7)-α-MSH; NDP-MSH. Grades: ≥95% by HPLC. CAS No. 75921-69-6. Molecular formula: C78H111N21O19. Mole weight: 1646.85. | |
| Meldonium dihydrate | Mildronate is a potent γ-butyrobetaine hydroxylase inhibitor, with a half maximal inhibitory concentration (IC50) value of 62 μM. Uses: Adjuvants, immunologic. Synonyms: Mildronate dihydrate; Mildronate (dihydrate); 3-(2,2,2-Trimethylhydrazinium)propionate dihydrate; 1,1,1-Trimethyl-2-(2-carboxyethyl)hydrazine zwitterion dihydrate. Grades: >98%. CAS No. 86426-17-7. Molecular formula: C6H18N2O4. Mole weight: 182.22. | |
| Melittin (honeybee) | Melittin is a polypeptide isolated from the venom of the honey bee (Apis mellifera). It inhibits protein kinase C, Ca2+/calmodulin-dependent protein kinase II, myosin light chain kinase and Na+/K+-ATPase (synaptosomal membrane). Synonyms: Honeybee melittin; Bee venom melittin; Forapin; H-Gly-Ile-Gly-Ala-Val-Leu-Lys-Val-Leu-Thr-Thr-Gly-Leu-Pro-Ala-Leu-Ile-Ser-Trp-Ile-Lys-Arg-Lys-Arg-Gln-Gln-NH2; glycyl-L-isoleucyl-glycyl-L-alanyl-L-valyl-L-leucyl-L-lysyl-L-valyl-L-leucyl-L-threonyl-L-threonyl-glycyl-L-leucyl-L-prolyl-L-alanyl-L-leucyl-L-isoleucyl-L-seryl-L-tryptophyl-L-isoleucyl-L-lysyl-L-arginyl-L-lysyl-L-arginyl-L-glutaminyl-L-glutaminamide. Grades: ≥98%. CAS No. 20449-79-0. Molecular formula: C131H229N39O31. Mole weight: 2846.46. | |
| Memantine Fructosyl Conjugate | Memantine Fructosyl Conjugate is one of memantine derivatives. Memantine, also called Namenda, a N-methyl D-aspartate (NMDA) antagonist prescribed to treat symptoms of moderate to severe Alzheimer's, blocks the toxic effects associated with excess glutamate and regulates glutamate activation. Molecular formula: C18H31NO5. Mole weight: 341.44. | |
| Memantine-Galactose Adduct | Memantine-Galactose Adduct is one of memantine derivatives. Memantine, also called Namenda, a N-methyl D-aspartate (NMDA) antagonist prescribed to treat symptoms of moderate to severe Alzheimer's, blocks the toxic effects associated with excess glutamate and regulates glutamate activation. Molecular formula: C18H31NO5. Mole weight: 341.44. | |
| Memantine-Galactose Adduct 1 | Memantine-Galactose Adduct 1 is a derivative of memantine. Memantine, also called Namenda, a N-methyl D-aspartate (NMDA) antagonist prescribed to treat symptoms of moderate to severe Alzheimer's, blocks the toxic effects associated with excess glutamate and regulates glutamate activation. Molecular formula: C18H31NO5. Mole weight: 341.44. | |
| Memantine-Glucose Adduct | Memantine-Glucose Adduct is one of memantine derivatives. Memantine, also called Namenda, a N-methyl D-aspartate (NMDA) antagonist prescribed to treat symptoms of moderate to severe Alzheimer's, blocks the toxic effects associated with excess glutamate and regulates glutamate activation. Molecular formula: C18H31NO5. Mole weight: 341.44. | |
| Memantine-glucose Adduct 1 | Memantine-glucose Adduct 1 is one of memantine derivatives. Memantine, also called Namenda, a N-methyl D-aspartate (NMDA) antagonist prescribed to treat symptoms of moderate to severe Alzheimer's, blocks the toxic effects associated with excess glutamate and regulates glutamate activation. Molecular formula: C18H31NO5. Mole weight: 341.44. | |
| Memantine Glucuronic Acid Conjugate | Memantine Glucuronic Acid Conjugate is an derivative of Memantine. Memantine, also called Namenda, a N-methyl D-aspartate (NMDA) antagonist prescribed to treat symptoms of moderate to severe Alzheimer's, blocks the toxic effects associated with excess glutamate and regulates glutamate activation. Molecular formula: C18H29NO6. Mole weight: 355.42. | |
| Memantine Glycine | Memantine Glycine is an impurity of Memantine, which is a medication used to slow the progression of moderate-to-severe Alzheimer's disease. Synonyms: N-(3,5-Dimethyltricyclo[3.3.1.13,7]dec-1-yl)glycine; N-(3,5-Dimethyladamantan-1-yl)glycine; Glycine, N-(3,5-dimethyltricyclo[3.3.1.13,7]dec-1-yl)-. Grades: ≥95%. CAS No. 1340545-88-1. Molecular formula: C14H23NO2. Mole weight: 237.34. | |
| Memantine-Glycine Adduct HCl | Memantine-Glycine Adduct HCl is an derivative of Memantine. Memantine, also called Namenda, a N-methyl D-aspartate (NMDA) antagonist prescribed to treat symptoms of moderate to severe Alzheimer's, blocks the toxic effects associated with excess glutamate and regulates glutamate activation. Synonyms: N-(3,5-dimethyltricyclo[3.3.1.13,7]dec-1-yl)-glycine, hydrochloride (1:1); N-(3,5-Dimethyladamantan-1-yl)glycine hydrochloride; Glycine, N-(3,5-dimethyltricyclo[3.3.1.13,7]dec-1-yl)-, hydrochloride (1:1). Molecular formula: C14H23NO2.HCl. Mole weight: 273.80. | |
| Memantine Glycine tert-Butyl Ester | Memantine Glycine tert-Butyl Ester is one of memantine derivatives. Memantine, also called Namenda, a N-methyl D-aspartate (NMDA) antagonist prescribed to treat symptoms of moderate to severe Alzheimer's, blocks the toxic effects associated with excess glutamate and regulates glutamate activation. Synonyms: 2-Methyl-2-propanyl N-(3,5-dimethyladamantan-1-yl)glycinate; Glycine, N-(3,5-dimethyltricyclo[3.3.1.13,7]dec-1-yl)-, 1,1-dimethylethyl ester. Grades: 98%. CAS No. 1537550-23-4. Molecular formula: C18H31NO2. Mole weight: 293.44. | |
| Menaquinone 4 | Menaquinone 4 is a homolog of vitamin K2 with four isoprene residue in its side chain. Menaquinone 4 is the most common type of vitamin K2 and can be used for the pain of osteoporosis. Uses: Hemostatics. Synonyms: 1,4-Naphthalenedione, 2-methyl-3-[(2E,6E,10E)-3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraen-1-yl]-; 1,4-Naphthalenedione, 2-methyl-3-(3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraenyl)-, (E,E,E)-; 1,4-Naphthalenedione, 2-methyl-3-[(2E,6E,10E)-3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraenyl]-; 2-Methyl-3-[(2E,6E,10E)-3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraen-1-yl]-1,4-naphthalenedione; 2-Methyl-3-geranylgeranyl-1,4-naphthoquinone; Glakay; K-viton; Kaytwo; Menaquinone K4; Menatetrenone; MK-4; Vitamin K2; Vitamin K2(20); Vitamin K2-4; Vitamin MK 4. Grades: ≥95%. CAS No. 863-61-6. Molecular formula: C31H40O2. Mole weight: 444.65. | |
| Menaquinone 5 | . Uses: Vitamin (prothrombogenic). Synonyms: Menaguinone. Grades: 95%. CAS No. 1182-68-9. Molecular formula: C36H48O2. Mole weight: 512.77. | |
| Menaquinone 6 | Menaquinone 6 is a vitamin K2 homolog. Synonyms: Farnoquinone; Menaquinone-6; Vitamin MK6; Vitamin K2(30); 2-[(2E,6E,10E,14E,18E)-3,7,11,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaenyl]-3-methylnaphthalene-1,4-dione. CAS No. 84-81-1. Molecular formula: C41H56O2. Mole weight: 580.897. | |
| Meprednisone 17,21-Diacetate | Meprednisone 17,21-Diacetate is an impurity of Prednisone, which is a synthetic anti-inflammatory glucocorticoid used to treat inflammatory or immune-mediated responses, as well as endocrine or neoplastic diseases. Molecular formula: C26H32O7. Mole weight: 456.53. | |
| Mequitazine | Mequitazine, an antihistamine, is a potent, nonsedative and long-acting histamine H1 antagonist. Synonyms: 10-(1-Azabicyclo[2.2.2]oct-3-ylmethyl)-10H-phenothiazine; 10-(3-Quinuclidinylmethyl)phenothiazine; Butix; LM 209; Metaplexan; Mircol; NSC 303612; Nipolazin; Primalan; Quitadrill; Zesulan. Grades: ≥95%. CAS No. 29216-28-2. Molecular formula: C20H22N2S. Mole weight: 322.47. | |
| Mesalamine Impurity P | 5-Amino-3-(4-sulfonylphenyl)salicyclic Acid is an impurity of mesalamine. Mesalamine is the active metabolite of Sulfasalazine. Synonyms: 5-Amino-3-(4-sulfonylphenyl)salicyclic Acid; 5-Amino-2-hydroxy-4'-sulfo-[1,1'-Biphenyl]-3-carboxylic Acid. Grades: > 95%. CAS No. 887256-40-8. Molecular formula: C13H11NO6S. Mole weight: 309.29. | |
| Mesalamine Impurity S | An impurity of mesalamine. Mesalamine is a medication used to treat ulcerative colitis. Synonyms: N-(2-carboxy-4-aminophenyl)-5-aminosalicylic Acid; 5-Amino-2-((3-carboxy-4-hydroxyphenyl)amino)benzoic Acid; 2-Hydroxy-5-Amino-N-(2-carboxy-4-aminophenyl)benzoic Acid. Grades: > 95%. CAS No. 1797983-23-3. Molecular formula: C14H12N2O5. Mole weight: 288.26. | |
| Metanephrine Sulfate Sodium Salt | An impurity of Epinephrine. Epinephrine is an endogenous catcholamine with combined α-and β-agonist activity and its principal sympathomimetic hormone is produced by the adrenal medulla. Synonyms: Sodium 4-(1-hydroxy-2-(methylamino)ethyl)-2-methoxyphenyl sulfate. Grades: >95%. Molecular formula: C10H14NO6SNa. Mole weight: 299.28. | |
| Metapramine | Metapramine, a low-affinity NMDA receptor antagonist, is a tricyclic antidepressant (TCA) used to treat depression. In addition to its efficacy against affective disorders, it has analgesic properties and may be useful in treating pain. It is a norepinephrine reuptake inhibitor without affecting serotonin or dopamine reuptake. Uses: Antidepressive agents, tricyclic. Synonyms: 10,11-Dihydro-N,5-dimethyl-5H-Dibenz[b,f]azepin-10-amine; 5-Methyl-10-methylamino-10,11-dihydrodibenzo[b,f]azepine; Metapramine; RP 19560; 10,11-Dihydro-5-methyl-10-5H-Dibenz[b,f]azepine. Grades: 95%. CAS No. 21730-16-5. Molecular formula: C16H18N2. Mole weight: 238.33. | |
| Metaraminol Bitartrate | Metaraminol is a stereoisomer of meta-hydroxynorephedrine, acting as an adrenergic agonist that increases both systolic and diastolic blood pressure. It can be used in the prevention and treatment of hypotension, particularly as a complication of anesthesia. Uses: Adrenergic alpha-1 receptor agonists. Synonyms: Metaraminol (+)-Bitartrate Salt; Metaraminol (Tartrate). Grades: ≥95.0%. CAS No. 33402-03-8. Molecular formula: C9H13NO2.C4H6O6. Mole weight: 317.29. | |
| Metformin EP Impurity B | Metformin EP Impurity B is an impurity of Metformin (HCl), an oral hypoglycemic agent that slows electron transport in the oxidation pathway in mitochondria. Guanylmelamine is a guanidino compound with antitumor activity. It is also a neoplasm inhibitor. Synonyms: Guanylmelamine; N-(4-Amino-3,6-dihydro-6-imino-1,3,5-triazin-2-yl)-guanidine; (4,6-Diamino-1,3,5-triazin-2-yl)-guanidine; (4,6-Diamino-s-triazin-2-yl)-guanidine; (Aminoiminomethyl)-1,3,5-triazine-2,4,6-triamine; Monoguanylmelamine. Grades: > 95%. CAS No. 4405-8-7. Molecular formula: C4H8N8. Mole weight: 168.16. | |
| Methazolamide | Methazolamide is a carbonic anhydrase inhibitor with Ki of 50 nM, 14 nM and 36 nM for hCA I, hCA II and bCA IV isoforms, respectively. Uses: Carbonic anhydrase inhibitors; diuretics. Synonyms: CL 8490; CL8490; CL-8490. Grades: >98%. CAS No. 554-57-4. Molecular formula: C5H8N4O3S2. Mole weight: 236.27. | |
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