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Methotrexate α-Methyl Ester
Cas No. 66147-29-3.
Methotrexate-Cadaverine-Biotin Conjugate
Methotrexate-Cadaverine-Biotin Conjugate is a biotin labelled Methotrexate, which is a folic acid antagonist used as an antineoplastic and antirheumatic. Synonyms: N2- (4-{[ (2, 4-Diamino-6-pteridinyl)methyl] (methyl)amino}benzoyl)-N-[5- ({5-[ (3aS, 4S, 6aR)-2-oxohexahydro-1H-thieno[3, 4-d]imidazol-4-yl]pentanoyl}amino)pentyl]-L-glutamine; L-Glutamine, N2-[4-[[ (2, 4-diamino-6-pteridinyl) methyl]methylamino]benzoyl]-N-[5-[[5-[ (3aS, 4S, 6aR) -hexahydro-2-oxo-1H-thieno[3, 4-d]imidazol-4-yl]-1-oxopentyl]amino]pentyl]-. Grades: 95%. Molecular formula: C35H48N12O6S. Mole weight: 764.90.
Methotrexate disodium
Methotrexate (Amethopterin) disodium, an antimetabolite and antifolate agent, inhibits the dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Methotrexate disodium, also an immunosuppressant and antineoplastic agent, is used for the research of rheumatoid arthritis and a number of different cancers (such as acute lymphoblastic leukemia). Synonyms: Amethopterin Sodium; Methotrexate Lederle; Metoart; Metotrexato Lederle; Sodium Methotrexate; N-[4-[[ (2, 4-Diamino-6-pteridinyl) methyl]methylamino]benzoyl]-L-glutamic Acid Disodium Salt; 4-amino-n(sup10)-methyl pteroyl glutamic acid disodium salt; amethopterin sodium. Grades: >98.0%. CAS No. 7413-34-5. Molecular formula: C20H20N8Na2O5. Mole weight: 498.40.
Methotrexate EP Impurity L
An impurity of Methotrexate, an antimetabolite and immunosuppressant used in chemotherapy and auto-immune diseases. This impurity also acts as an inhibitor of human DNA methyltransferase. Synonyms: N-(4-(Methylamino)benzoyl)-L-glutamic acid; N-(p-(Methylamino)benzoyl)glutamic acid; (p-Methylaminobenzoyl)-L-glutamic Acid; N-[p-(Methylamino)benzoyl]-L-glutamic acid; NSC 138419. Grades: > 95%. CAS No. 52980-68-4. Molecular formula: C13H16N2O5. Mole weight: 280.28.
Methotrexate Heptaglutamate Trifluoroacetate
Methotrexate Heptaglutamate Trifluoroacetate is one of methotrexate metabolites. Methotrexate is a Folic Acid antagonist, used as an antineoplastic and antirheumatic. Synonyms: Methotrexate Heptaglutamate Trifluoroacetate; Methotrexate Tetraglutamate Trifluoroacetate. Grades: 96%. Molecular formula: C50H64N14O23.xC2HF3O2. Mole weight: 1229.12 (free base).
Methotrexate Hexaglutamate Trifluoroacetate
Methotrexate Hexaglutamate Trifluoroacetate is one of methotrexate metabolites. Methotrexate is a Folic Acid antagonist, used as an antineoplastic and antirheumatic. Synonyms: N-[4-[[ (2, 4-Diamino-6-pteridinyl) methyl]methylamino]benzoyl]-L-γ -glutamyl-L-γ -glutamyl-L-γ -glutamyl-L-γ -glutamyl-L-γ -glutamyl-L-glutamic Acid Trifluoroacetate; N-[N-[N-[N-[N-[N-[4-[[ (2, 4-Diamino-6-pteridinyl) methyl]methylamino]benzoyl]-L-γ -glutamyl]-L-γ -glutamyl]-L-γ -glutamyl]-L-γ -glutamyl]-L-γ -glutamyl]-L-glutamic Acid Trifluoroacetate. Grades: 98%. Molecular formula: C45H57N13O20.xC2HF3O2. Mole weight: 1100.01 (free base).
Methotrexate Impurity B
Cas No. 54-62-6.
Methotrexate Impurity E
Cas No. 19741-14-1.
Methotrexate Pentaglutamate Trifluoroacetate
Methotrexate Pentaglutamate Trifluoroacetate is one of methotrexate metabolites. Methotrexate is a Folic Acid antagonist, used as an antineoplastic and antirheumatic. Synonyms: N-[4-[[ (2, 4-Diamino-6-pteridinyl) methyl]methylamino]benzoyl]-L-γ -glutamyl-L-γ -glutamyl-L-γ -glutamyl-L-γ -glutamyl-L-glutamic Acid Trifluoroacetate; N-[N-[N-[N-[N-[4-[[ (2, 4-Diamino-6-pteridinyl) methyl]methylamino]benzoyl]-L-γ -glutamyl]-L-γ -glutamyl]-L-γ -glutamyl]-L-γ -glutamyl]-L-glutamic Acid Trifluoroacetate; MTXPG5 Trifluoroacetate. Grades: 96%. Molecular formula: C40H50N12O17.xC2HF3O2. Mole weight: 970.89 (free base).
Methotrexate Tetraglutamate Trifluoroacetate
Methotrexate Tetraglutamate Trifluoroacetate is one of Methotrexate metabolites. Methotrexate is a Folic Acid antagonist, used as an antineoplastic and antirheumatic. Synonyms: N-[4-[[ (2, 4-Diamino-6-pteridinyl) methyl]methylamino]benzoyl]-L-γ -glutamyl-L-γ -glutamyl-L-γ -glutamyl-L-glutamic Acid Trifluoroacetate; N-[N-[N-[N-[4-[[ (2, 4-Diamino-6-pteridinyl) methyl]methylamino]benzoyl]-L-γ -glutamyl]-L-γ -glutamyl]-L-γ -glutamyl]-L-glutamic Acid Trifluoroacetate; MTXPG4 Trifluoroacetate. Grades: 98%. Molecular formula: C35H43N11O14.xC2HF3O2. Mole weight: 841.78 (free base).
Methotrexate Triglutamate Trifluoroacetate
Methotrexate Triglutamate Trifluoroacetate is one of Methotrexate metabolites. Methotrexate is a Folic Acid antagonist, used as an antineoplastic and antirheumatic. Synonyms: N-[4-[[ (2, 4-Diamino-6-pteridinyl) methyl]methylamino]benzoyl]-L-γ -glutamyl-L-γ -glutamyl-L-glutamic Acid Trifluoroacetate; 2,4-Diamino-N10-methylpteroylglutamyl-γ-glutamyl-γ-glutamic Acid Trifluoroacetate; 4-Amino-10-methylpteroylglutamyl-γ-diglutamic Acid Trifluoroacetate; 4-Amino-10-methylpteroylglutamyl-γ-glutamyl-γ-glutamic Acid Trifluoroacetate; MTXPG3 Trifluoroacetate; NSC 341076 Trifluoroacetate. Grades: 96%. Molecular formula: C30H36N10O11.xC2HF3O2. Mole weight: 712.67 (free base).
Methoxsalen
Cas No. 298-81-7.
Methoxy Empagliflozin
Methoxy Empagliflozin is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: (2R,3R,4R,5S,6S)-2-(Acetoxymethyl)-6-(4-chloro-3-(4-methoxybenzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl Triacetate; 1,5-Anhydro-1-C-[4-chloro-3-[(4-methoxyphenyl)methyl]phenyl]-, 2,3,4,6-tetraacetate-D-glucitol. CAS No. 872980-38-6. Molecular formula: C28H31ClO10. Mole weight: 562.99.
Methoxy Montelukast Methyl Ester
Methoxy Montelukast Methyl Ester is an intermediate of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Synonyms: methyl 2- [1- [ [ (1R) -1- [3- [ (E) -2- (7-chloroquinolin-2-yl) ethenyl] phenyl] -3- [2- (2-methoxypropan-2-yl) phenyl] propyl] sulfanylmethyl] cyclopropyl] acetate. Molecular formula: C37H40ClNO3S. Mole weight: 614.23.
An impurity of Nintedanib, which is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50 of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/66 nM. Synonyms: 1160293-25-3; methyl 1-(2-chloroacetyl)-2-oxoindoline-6-carboxylate1-(2-chloroacetyl)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl estermethyl 1-(2-chloroacetyl)-2-oxo-3H-indole-6-carboxylate1H-Indole-6-carboxylic acid, 1-(2-chloroacetyl)-2,3-dihydro-2-oxo-, methyl ester. Grades: 95%. CAS No. 1160293-25-3. Molecular formula: C12H10ClNO4. Mole weight: 267.66.
Methyl 13-cis-4-Oxoretinoate
Methyl 13-cis-4-Oxoretinoate is a derivative of retinoic acid. Synonyms: 4-Keto 13-cis-Retinoic Acid Methyl Ester; methyl (2Z,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethyl-3-oxocyclohexen-1-yl)nona-2,4,6,8-tetraenoate. CAS No. 71748-57-7. Molecular formula: C21H28O3. Mole weight: 328.452.
Methyl 1-Acetyl-2-oxoindoline-6-carboxylate
An impurity of Nintedanib, a receptor tyrosine kinase (RTK) inhibitor that binds to vascular endothelial growth factor receptor, fibroblast growth factor receptor and platelet derived growth factor receptor. Nintedanib is used as a medication for the treatment of idiopathic pulmonary fibrosis. Synonyms: 1-acetyl-2-oxo-3H-indole-6-carboxylic acid methyl ester; methyl 1-acetyl-2-oxo-3H-indole-6-carboxylate. CAS No. 676326-36-6. Molecular formula: C12H11NO4. Mole weight: 233.22.
Methyl 2-(2-Acetoxy-5-(tert-butyl)-4-nitrophenyl)-2-methylpropanoate is an intermediate in the synthesis of Ivacaftor, which is a CFTR potentiator used in the treatment of cystic fibrosis. Molecular formula: C17H23NO6. Mole weight: 337.37.
Methyl 2-(2-Cyclopropylethynyl)benzoate
Methyl 2-(2-Cyclopropylethynyl)benzoate is an intermediate in the synthesis of Digoxigenin Tetradigitoxoside, which is an impurity of Digoxin. Synonyms: Methyl 2-(cyclopropylethynyl)benzoate; Benzoic acid, 2-(2-cyclopropylethynyl)-, methyl ester. Grades: ≥95%. CAS No. 1357469-11-4. Molecular formula: C13H12O2. Mole weight: 200.23.
methyl 2',3'-dichloro-3-methyl-5-oxo-1,2,5,6-tetrahydro-[1,1'-biphenyl]-2-carboxylate is an impurity of clevidipine, a dihydropyridine calcium channel blocker used as an oral antihypertensive drug. Synonyms: Methyl 6-(2,3-dichlorophenyl)-2-methyl-4-oxo-2-cyclohexene-1-carboxylate; 6-(2,?3-Dichlorophenyl)?-2-methyl-4-oxo-2-cyclohexene-1-carboxylic acid Methyl Ester. CAS No. 1801167-49-6. Molecular formula: C15H14Cl2O3. Mole weight: 313.18.
methyl 2',3'-dichloro-5-methyl-3-oxo-1,2,3,6-tetrahydro-[1,1'-biphenyl]-2-carboxylate is an impurity of clevidipine, a dihydropyridine calcium channel blocker used as an oral antihypertensive drug. Synonyms: Methyl 6-(2,3-dichlorophenyl)-4-methyl-2-oxo-3-cyclohexene-1-carboxylate. CAS No. 1207068-15-2. Molecular formula: C15H14Cl2O3. Mole weight: 313.18.
Methyl 2,5-dihydroxycinnamate
Methyl 2,5-dihydroxycinnamate, a stable analog of erbstatin, is a stable, potent inhibitor of EGFR kinase activity. It is described to be four-times more stable than erbstatin in calf serum2. It was shown to delay the S-phase induction by epidermal growth factor in quiescent normal rat kidney cells, without affecting the total amount of DNA synthesis. Synonyms: Methyl 2,5-dihydoxycinnamate; 3-(2,5-dihydroxyphenyl)-2-propenoic acid, methyl ester; Erbstatin Analog. Grades: ≥98% by HPLC. CAS No. 63177-57-1. Molecular formula: C10H10O4. Mole weight: 194.19.
Methyl 2-(5H-chromeno[2,3-b]pyridin-7-yl)propanoate is an impurity of Pranoprofen. Pranoprofen is a non-steroidal anti-inflammatory drug. Synonyms: Pranoprofen Impurity 10. CAS No. 145986-74-9. Molecular formula: C16H15NO3. Mole weight: 269.30.
Methyl 2,6-Dideoxy-3,4-bis-O-[(1,1-dimethylethyl)diphenylsilyl]-α-D-ribo-hexopyranoside is an intermediate in the synthesis of Digoxigenin Tetradigitoxoside, which is an impurity of Digoxin. Synonyms: Methyl 2,6-dideoxy-3,4-bis-O-[(2-methyl-2-propanyl)(diphenyl)silyl]-α-D-ribo-hexopyranoside; tert-butyl-[(2R,3R,4S,6S)-3-[tert-butyl(diphenyl)silyl]oxy-6-methoxy-2-methyloxan-4-yl]oxy-diphenylsilane; Methyl 3,4-di-O-(tert-butyl-diphenyl-silyl)-2,6-dideoxy-alpha-D-ribo-hexopyranoside; α-D-ribo-Hexopyranoside, methyl 2,6-dideoxy-3,4-bis-O-[(1,1-dimethylethyl)diphenylsilyl]-. CAS No. 1345697-38-2. Molecular formula: C39H50O4Si2. Mole weight: 638.98.
Methyl 2-Amino-2-(2-Chlorophenyl)Acetate
Methyl 2-Amino-2-(2-Chlorophenyl)Acetate is an impurity of Clopidogrel, an antithrombotic agent. Synonyms: (2S,2'S)-dimethyl2,2'-(2,2'-methylenebis(6,7-dihydrothieno[3,2-c]pyridine-5,2(4H)-diyl))bis(2-(2-chlorophenyl)acetate) dihydrochloride; methyl amino(2-chlorophenyl)acetate hydrochloride; methyl amino(2-chlorophenyl)acetate HCl; Clopidogrel Impurity 31. CAS No. 141109-17-3. Molecular formula: C9H11Cl2NO2. Mole weight: 236.09.
Methyl 2-Deoxy-4,6-O-(phenylmethylene)-α-D-ribo-hexopyranoside is an intermediate in the synthesis of Digoxigenin Tetradigitoxoside, which is an impurity of Digoxin. Synonyms: (4aR,6S,8S,8aS)-6-methoxy-2-phenylhexahydropyrano[3,2-d][1,3]dioxin-8-ol; Methyl 2-deoxy-4-O,6-O-benzylidene-alpha-D-allopyranoside; Methyl 4,6-O-Benzylidene-2-deoxy-α-D-ribo-hexopyranoside; α-D-ribo-Hexopyranoside, methyl 2-deoxy-4,6-O-(phenylmethylene)-. Grades: ≥95%. CAS No. 16718-95-9. Molecular formula: C14H18O5. Mole weight: 266.29.
Methyl 2-Deoxy-4,6-O-(phenylmethylene)-α-D-ribo-Hexopyranoside Benzoate is an intermediate in the synthesis of Digoxigenin Tetradigitoxoside, which is an impurity of Digoxin. Synonyms: Methyl 3-O-benzoyl-4,6-O-benzylidene-2-deoxy-α-D-ribo-hexopyranoside; α-D-ribo-Hexopyranoside, methyl 2-deoxy-4,6-O-(phenylmethylene)-, benzoate; D-ribo-Hexopyranoside, methyl 4,6-O-benzylidene-2-deoxy-, benzoate, α-; Pyrano[3,2-d]-1,3-dioxin, α-D-ribo-hexopyranoside deriv.; NSC 287053. CAS No. 32469-89-9. Molecular formula: C21H22O6. Mole weight: 370.39.
methyl 2-fluoro-3-oxopentanoate
One of the impurities of Voriconazole, which has been found to be an ergosterol biosynthesis inhibitor and could be used as an antifungal agent. Synonyms: pentanoic acid, 2-fluoro-3-oxo-, methyl ester; Voriconazole Impurity 23. CAS No. 180287-02-9. Molecular formula: C6H9FO3. Mole weight: 148.13.
methyl 3'-amino-2'-hydroxy-[1,1'-biphenyl]-3-carboxylate is an impurity of Eltrombopag, a drug used in the treatment of thrombocytopenia (abnormally low platelet count) for severe aplastic anemia. CAS No. 2230800-88-9. Molecular formula: C14H13NO3. Mole weight: 243.26.
Methyl 3-(trimethylsilyl)-4-pentenoate
An impurity of Eribulin. Uses: Methyl 3-(trimethylsilyl)-4-pentenoate, can be used in the synthesis of eribulin (e615203), a synthetic analog of the marine natural product halichondrin b. Synonyms: methyl 3-trimethylsilylpent-4-enoate. Grades: > 95 %. CAS No. 185411-12-5. Molecular formula: C9H18O2Si. Mole weight: 186.32.
An impurity of Riociguat. Riociguat is used in the treatment for pulmonary hypertension. Synonyms: Riociguat Impurity 27; Carbamic acid, N-[4,6-diamino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl]-N-ethyl-, methyl ester. CAS No. 1361570-27-5. Molecular formula: C21H21FN8O2. Mole weight: 436.44.
Methyl 4-Acetamido-2-hydroxybenzoate
Methyl 4-Acetamido-2-hydroxybenzoate is a reagent used in the synthesis of Mosapride, which is a 5-HT4 receptor agonist and 5-HT3 receptor antagonist used as a gastroprokinetic agent. Synonyms: 4-(Acetylamino)-2-hydroxy-benzoic Acid Methyl Ester; 4-Acetylaminosalicylic Acid Methyl Ester; Methyl 2-Hydroxy-4-(acetylamino)benzoate; Methyl 4-(Acetylamino)salicylate; Methyl 4-Acetamidosalicylate; USP Ethopabate Related Compound A. Grades: ≥95%. CAS No. 4093-28-1. Molecular formula: C10H11NO4. Mole weight: 209.20.
Methyl 4-Chlorobenzoate
Methyl 4-Chlorobenzoate is a reactant used in the synthesis of ataxia-telangiectasia mutated (ATM) kinase, a target for novel radiosensitizing agents. As well, it is used as a reactant in the synthesis of aminopyridine functionalized polyacrylonitrile fibers. Synonyms: 4-chlorobenzoic acid methyl ester; methyl 4-chlorobenzoate. Grades: > 95 %. CAS No. 1126-46-1. Molecular formula: C8H7ClO2. Mole weight: 170.59.
Methyl 4-Ethoxy-1,3-dimethyl-1H-pyrazole-5-carboxylate is an intermediate of Clenbuterol and is used as a reagent in the synthesis of pyrazolopyridine derivatives as inhibitors of phosphodiesterase-4 (PDE-IV) and production of tumor necrosis factor-α (TNF-α). Synonyms: 1H-Pyrazole-5-carboxylic acid, 4-ethoxy-1,3-dimethyl-, methyl ester; 4-Ethoxy-1,3-dimethyl-1H-pyrazole-5-carboxylate methyl ester. Molecular formula: C9H14N2O3. Mole weight: 198.22.
Methyl 5,6,7,8-tetrahydronaphthalene-1-carboxylate is used in the preparation of Palonosetron, which is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Synonyms: 1-Naphthalenecarboxylic acid, 5,6,7,8-tetrahydro-, Methyl ester; Methyl tetralin-5-carboxylate; Methyl 5,6,7,8-tetrahydro-1-naphthalenecarboxylate; Methyl 1,2,3,4-tetrahydro-5-naphthalenecarboxylate; 5,6,7,8-tetrahydro-[1]naphthoic acid methyl ester. Grades: ≥95%. CAS No. 66193-59-7. Molecular formula: C12H14O2. Mole weight: 190.24.
Methyl 5,6-Monoepoxyretinoate
Methyl 5,6-Monoepoxyretinoate is an impurity in the synthesis of Ro 22-5112, a retinoid. Synonyms: 5,6-Epoxy-5,6-dihydroretinoic acid methyl ester; Retinoic acid, 5,6-epoxy-5,6-dihydro-, methyl ester; 2,4,6,8-Nonatetraenoic acid, 3,7-dimethyl-9-(2,2,6-trimethyl-7-oxabicyclo[4.1.0]hept-1-yl)-, methyl ester, (2E,4E,6E,8E)-. CAS No. 7432-30-6. Molecular formula: C21H30O3. Mole weight: 330.46.
Methyl 6-(4-Methoxyphenyl)-2-naphthoate
Methyl 6-(4-Methoxyphenyl)-2-naphthoate is an intermediate in the synthesis of Adapalene, which is a third-generation topical retinoid primarily used in the treatment of mild-moderate acne. Synonyms: 6-(4-Methoxyphenyl)-2-naphthalenecarboxylic Acid Methyl Ester; 6-(4-Methoxyphenyl)-2-naphthoic Acid Methyl Ester. Grades: ≥95%. CAS No. 128272-36-6. Molecular formula: C19H16O3. Mole weight: 292.33.
Methyl 6-Bromo-2,6-dideoxy-α-D-ribo-hexopyranoside Dibenzoate is an intermediate in the synthesis of Digoxigenin Tetradigitoxoside, which is an impurity of Digoxin. Synonyms: Methyl 3,4-di-O-benzoyl-6-bromo-2,6-dideoxy-α-D-ribo-hexopyranoside; α-D-ribo-Hexopyranoside, methyl 6-bromo-2,6-dideoxy-, dibenzoate; (2S,3S,4S,6S)-2-(bromomethyl)-6-methoxytetrahydro-2H-pyran-3,4-diyl dibenzoate. CAS No. 18933-67-0. Molecular formula: C21H21BrO6. Mole weight: 449.29.
Methyl Aminolevulinate Hydrochloride is the methyl ester of Aminolevulinic Acid, which is a precursor of a photosensitizer and also is used as an add on agent for photodynamic therapy. It shows much higher lipophilicity and highly efficient at inducing protoporphyrin IXproduction in cell culture. Synonyms: Methyl 5-amino-4-oxopentanoate hydrochloride; Methyl 5-Aminolevulinate Hydrochloride; 5-Amino-4-oxopentanoic Acid Methyl Ester Hydrochloride. CAS No. 79416-27-6. Molecular formula: C6H12ClNO3. Mole weight: 181.616.
methyl (E)-3-(4-(methoxymethyl)phenyl)acrylate
methyl (E)-3-(4-(methoxymethyl)phenyl)acrylate is an impurity of Ozagrel, an antiplatelet drug that acts as a thromboxane A2 synthesis inhibitor. Synonyms: methyl (E)-3-(4-(methoxymethyl)phenyl)acrylate; AKOS020185360; 121379-29-1. CAS No. 121379-29-1. Molecular formula: C12H14O3. Mole weight: 206.24.
Methyl Flurbiprofen
Methyl Flurbiprofen is prodrug of Flurbiprofen. It is an intermediate for the synthesis of the metabolite of Flurbiprofen. Synonyms: 2-Fluoro-α-methyl-[1,1'-biphenyl]-4-acetic Acid Methyl Ester; Flurbiprofen Methyl Ester; Methyl 2-(2-fluoro-biphenyl-4-yl)propionate. Grades: > 95%. CAS No. 66202-86-6. Molecular formula: C16H15FO2. Mole weight: 258.30.
Methyl folate
Methyl folate is an active metabolite of folic acid. It acts as a methyl-group donor involved in the conversion of homocysteine to methionine in conjunction with vitamin B12. Vitamin supplement in health care products. Uses: Ingredient of health care products. Synonyms: Prefolic A; 5-Methyltetrahydrofolate; N-methyltetrahydrofolic acid; 5-Methyltetrahydropteroylglutamate. Grades: 95%. CAS No. 134-35-0. Molecular formula: C20H25N7O6. Mole weight: 459.46.
Methylprednisolone 17-Hydrogen Succinate
Methylprednisolone 17-Hydrogen Succinate is an impurity of Methyl Prednisolone. Prednisolone is a glucocorticoid and an anti-inflammatory drug used to treat central nervous system disorders. Synonyms: (6α,11β)-17-(3-Carboxy-1-oxopropoxy)-11,21-dihydroxy-6-methylpregna-1,4-diene-3,20-dione; Methylprednisolone Hydrogen Succinate EP Impurity B; 6α-Methyl Prednisolone 17-Hemisuccinate; Butanedioic acid, mono[(6α,11β)-11,21-dihydroxy-6-methyl-3,20-dioxopregna-1,4-dien-17-yl] ester. Grades: ≥95%. CAS No. 77074-42-1. Molecular formula: C26H34O8. Mole weight: 474.54.
Methylprednisolone Acetate EP Impurity D
Methylprednisolone Acetate EP Impurity D is an impurity of Methylprednisolone, which is a synthetic glucocorticoid used primarily for anti-inflammatory and immunosuppressive effects. Molecular formula: C44H58O9. Mole weight: 730.92.
Methylprednisolone EP Impurity A Hydrogen Succinate
Methylprednisolone EP Impurity A Hydrogen Succinate is an impurity of Methylprednisolone, which is a synthetic glucocorticoid used primarily for anti-inflammatory and immunosuppressive effects. Molecular formula: C26H32O8. Mole weight: 472.53.
Methylprednisolone EP impurity L
Cas No. 6870-94-6.
Methylprednisolone Impurity 5
Methylprednisolone Impurity 5 is an impurity of Methylprednisolone, which is a synthetic glucocorticoid used primarily for anti-inflammatory and immunosuppressive effects. Synonyms: 3H-Cyclopenta[a]phenanthren-3-one, (6S,8S,9S,10R,11S,13S,14S)-11-hydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-6,7,8,9,10,11,12,13,14,15-decahydro-. Molecular formula: C22H28O4. Mole weight: 356.45.
Methylprednisolone Impurity 6
Methylprednisolone Impurity 6 is an impurity of Methylprednisolone, which is a synthetic glucocorticoid used primarily for anti-inflammatory and immunosuppressive effects. Synonyms: (6α, 11β, 6'α, 11'β)-21, 21'-Oxybis(11, 17-dihydroxy-6-methylpregna-1, 4-diene-3, 20-dione). Molecular formula: C44H58O9. Mole weight: 730.92.
Methylprednisolone Impurity 9
Methylprednisolone Impurity 9 is an impurity of Methylprednisolone, which is a synthetic glucocorticoid used primarily for anti-inflammatory and immunosuppressive effects. Molecular formula: C30H38O11. Mole weight: 574.61.
Methyl triphenylmethyl ether
A metabolite of Olmesartan, which is a specific angiotensin II type 1 (AT1) receptor antagonist with antihypertensive effect. hAT1 receptors: IC50=6.24 nM. Synonyms: [methoxy(diphenyl)methyl]benzene. Grades: > 95 %. CAS No. 596-31-6. Molecular formula: C20H18O. Mole weight: 274.36.
An impurity of Nintedanib, which is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50 of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/73 nM. Synonyms: methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate; Nintedanib Impurity 06. CAS No. 2093243-16-2. Molecular formula: C17H13NO4. Mole weight: 295.29.
Metipranolol hydrochloride
Metipranolol is a non-selective β-adrenergic receptor antagonist. It has been utilized in eye drops for the treatment of glaucoma. Synonyms: Metipranolol HCl; [4-[2-hydroxy-3-(propan-2-ylamino)propoxy]-2,3,6-trimethylphenyl] acetate hydrochloride. Grades: ≥98%. CAS No. 36592-77-5. Molecular formula: C17H27NO4·HCl. Mole weight: 345.9.
[Met(O)18,Ser(tBu)1]-Teriparatide
[Met(O)18,Ser(tBu)1]-Teriparatide is an impurity of Teriparatide, which is an anabolic osteoporosis drug used to treat osteoporosis. Synonyms: Met(O)18,Ser(tBu)1-Teriparatide; O-tert-butyl-L-seryl-L-valyl-L-seryl-L-glutamyl-L-isoleucyl-L-glutaminyl-L-leucyl-L-methionyl-L-histidyl-L-asparagyl-L-leucyl-glycyl-L-lysyl-L-histidyl-L-leucyl-L-asparagyl-L-seryl-L-methionyl(O)-L-glutamyl-L-arginyl-L-valyl-L-alpha-glutamyl-L-tryptophyl-L-leucyl-L-arginyl-L-lysyl-L-lysyl-L-leucyl-L-glutaminyl-L-alpha-aspartyl-L-valyl-L-histidyl-L-asparagyl-L-phenylalanine; H-Ser(tBu)-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met(O)-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-OH. Molecular formula: C185H299N55O52S2. Mole weight: 4189.88.
[Met(O)18]-Teriparatide
[Met(O)18]-Teriparatide is an impurity of Teriparatide, which is an anabolic osteoporosis drug used to treat osteoporosis. Synonyms: Teriparatide Impurity 3 (Teri-Met 18(O)); L-seryl-L-valyl-L-seryl-L-glutamyl-L-isoleucyl-L-glutaminyl-L-leucyl-L-methionyl-L-histidyl-L-asparagyl-L-leucyl-glycyl-L-lysyl-L-histidyl-L-leucyl-L-asparagyl-L-seryl-L-methionyl(O)-L-glutamyl-L-arginyl-L-valyl-L-alpha-glutamyl-L-tryptophyl-L-leucyl-L-arginyl-L-lysyl-L-lysyl-L-leucyl-L-glutaminyl-L-alpha-aspartyl-L-valyl-L-histidyl-L-asparagyl-L-phenylalanine; Met(O)18-Teriparatide; H-Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met(O)-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-OH. Molecular formula: C181H291N55O52S2. Mole weight: 4133.77.
[Met(O)-8,18]-Teriparatide
[Met(O)-8,18]-Teriparatide is an impurity of Teriparatide, which is an anabolic osteoporosis drug used to treat osteoporosis. Synonyms: L-seryl-L-valyl-L-seryl-L-glutamyl-L-isoleucyl-L-glutaminyl-L-leucyl-L-methionyl(O)-L-histidyl-L-asparagyl-L-leucyl-glycyl-L-lysyl-L-histidyl-L-leucyl-L-asparagyl-L-seryl-L-methionyl(O)-L-glutamyl-L-arginyl-L-valyl-L-alpha-glutamyl-L-tryptophyl-L-leucyl-L-arginyl-L-lysyl-L-lysyl-L-leucyl-L-glutaminyl-L-alpha-aspartyl-L-valyl-L-histidyl-L-asparagyl-L-phenylalanine; Teriparatide Impurity-1 (Teri-Met 8&18 (O)); Met(O)-8,18-Teriparatide; H-Ser-Val-Ser-Glu-Ile-Gln-Leu-Met(O)-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met(O)-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-OH. Molecular formula: C181H291N55O53S2. Mole weight: 4149.77.
[Met(O)8,Ser(tBu)1]-Teriparatide
[Met(O)8,Ser(tBu)1]-Teriparatide is an impurity of Teriparatide, which is an anabolic osteoporosis drug used to treat osteoporosis. Synonyms: Met(O)8,Ser(tBu)1-Teriparatide; O-tert-butyl-L-seryl-L-valyl-L-seryl-L-glutamyl-L-isoleucyl-L-glutaminyl-L-leucyl-L-methionyl(O)-L-histidyl-L-asparagyl-L-leucyl-glycyl-L-lysyl-L-histidyl-L-leucyl-L-asparagyl-L-seryl-L-methionyl-L-glutamyl-L-arginyl-L-valyl-L-alpha-glutamyl-L-tryptophyl-L-leucyl-L-arginyl-L-lysyl-L-lysyl-L-leucyl-L-glutaminyl-L-alpha-aspartyl-L-valyl-L-histidyl-L-asparagyl-L-phenylalanine; H-Ser(tBu)-Val-Ser-Glu-Ile-Gln-Leu-Met(O)-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-OH. Molecular formula: C185H299N55O52S2. Mole weight: 4189.88.
[Met(O)8]-Teriparatide
[Met(O)8]-Teriparatide is an impurity of Teriparatide, which is an anabolic osteoporosis drug used to treat osteoporosis. Synonyms: Teriparatide Impurity 2 (Teri-Met 8(O)); L-seryl-L-valyl-L-seryl-L-glutamyl-L-isoleucyl-L-glutaminyl-L-leucyl-L-methionyl(O)-L-histidyl-L-asparagyl-L-leucyl-glycyl-L-lysyl-L-histidyl-L-leucyl-L-asparagyl-L-seryl-L-methionyl-L-glutamyl-L-arginyl-L-valyl-L-alpha-glutamyl-L-tryptophyl-L-leucyl-L-arginyl-L-lysyl-L-lysyl-L-leucyl-L-glutaminyl-L-alpha-aspartyl-L-valyl-L-histidyl-L-asparagyl-L-phenylalanine; Met(O)8-Teriparatide; H-Ser-Val-Ser-Glu-Ile-Gln-Leu-Met(O)-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-OH. Molecular formula: C181H291N55O52S2. Mole weight: 4133.77.
Metoclopramide Hydrochloride
Metoclopramide HCl is a selective dopamine D2 receptor antagonist, used for the treatment of nausea and vomiting. Synonyms: 2-(Methoxy)-5-chloroprocainamide; Clopromate; DEL 1267; Draclamid; Emperal; Eucil; Gastrese; Gastrobid; Gastromax; Gastrosil; Gastrote. Grades: >98%. CAS No. 7232-21-5. Molecular formula: C14H23Cl2N3O2. Mole weight: 336.26.
Metoclopramide hydrochloride hydrate
Metoclopramide hydrochloride hydrate is a dopamine D2 antagonist used to treat nausea and vomitin. Uses: A dopamine d2 antagonist. Synonyms: Maxolon; AHR-3070-C; Maxolon; Metoclopramide HCl; Metoclopramide hydrochloride; Metoclopramide monohydrochloride monohydrate; Metozolv; Reglah. Grades: ≥98%. CAS No. 54143-57-6. Molecular formula: C14H25Cl2N3O3. Mole weight: 354.3.
Metoprolol Related Compound D (USP)
Metoprolol Related Compound D (USP) is an impurity of Metoprolol, a β1 selective aryloxypropanolamine andrenergic antagonist. It is used in the treatment of a variety of cardiovascular disorder. Synonyms: Metoprolol Impurity 12; 1,1'-[(1-Methylethyl)imino]bis[3-[4-(2-methoxyethyl)phenoxy]propan-2-ol] Hydrochloride; N, N-Bis{2-hydroxy-3-[4- (2-methoxyethyl) phenoxy]propyl}isopropylamine Hydrochloride; (±) N,N-Bis[2-hydroxy-3-[4-(2-methoxyethyl)phenoxy]propyl](1-methylethyl)amine Hydrochloride; 3,3'-(isopropylazanediyl)bis(1-(4-(2-methoxyethyl)phenoxy)propan-2-ol) hydrochloride. Grades: 99% by HPLC. CAS No. 1486464-40-7. Molecular formula: C27H42ClNO6. Mole weight: 512.08.
Metronidazole Impurity D
An impurity of Metronidazole. Metronidazole is an antibacterial in the treatment of rosacea. Antiprotozoal (trichomonas). A potential human carcinogen. Synonyms: 2-(5-Nitro-1H-imidazol-1-yl)ethanol; 5-Nitro-1H-imidazole-1-ethanol; 1H-Imidazole-1-ethanol, 5-nitro-. Grades: > 95%. CAS No. 5006-68-8. Molecular formula: C5H7N3O3. Mole weight: 157.13.
Metronidazole Impurity E
An impurity of Metronidazole. Metronidazole is an antibacterial in the treatment of rosacea. Antiprotozoal (trichomonas). A potential human carcinogen. Synonyms: 2-Methyl-4-nitro-1H-imidazole-1-ethanol; 1-(2-Hydroxyethyl)-2-methyl-4-nitroimidazole. Grades: > 95%. CAS No. 705-19-1. Molecular formula: C6H9N3O3. Mole weight: 171.16.
Metronidazole Impurity F
An impurity of Metronidazole. Metronidazole is an antibacterial in the treatment of rosacea. Antiprotozoal (trichomonas). A potential human carcinogen. Synonyms: 2-[2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethoxy]ethanol; Metronidazole Impurity F; 2-[2-(2-Methyl-5-nitroimidazol-1-yl)ethoxy]ethanol;O-Hydroxyethyl Metronidazole. Grades: > 95%. CAS No. 16156-94-8. Molecular formula: C8H13N3O4. Mole weight: 215.21.
Metronidazole Impurity G
An impurity of Metronidazole. Metronidazole is an antibacterial in the treatment of rosacea. Antiprotozoal (trichomonas). A potential human carcinogen. Synonyms: 2-Methyl-5-nitroimidazol-1-ylacetic Acid; 1-De(2-hydroxyethyl)metronidazole-1-acetic Acid; 2-Methyl-5-nitro-1H-imidazole-1-acetic Acid; 2-Methyl-5-nitro-Imidazole-1-acetic Acid; Metronidazoleacetic Acid. Grades: > 95%. CAS No. 1010-93-1. Molecular formula: C6H7N3O4. Mole weight: 185.14.
Mezlocillin
Mezlocillin is a broad-spectrum, beta-lactam penicillin antibiotic with antibacterial activity. It belongs semisynthetic ampicillin-derived acylureido penicillin. It is active against both Gram-negative and some Gram-positive bacteria. It inhibits the third and last stage of bacterial cell wall synthesis by binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall. It has been proposed for infections with certain anaerobes and may be useful in inner ear, bile, and CNS infections. It is excreted by the liver, therefore it is useful for biliary tract infections, such as ascending cholangitis. Uses: Mezlocillin has antibacterial activity. it is active against both gram-negative and some gram-positive bacteria. it is excreted by the liver, therefore it is useful for biliary tract infections, such as ascending cholangitis. Synonyms: BAY-f 1353; 6beta-{(2R)-2-[3-(methanesulfonyl)-2-oxoimidazolidine-1-carboxamido]-2-phenylacetamido}penicillanic acid; [2S- [2α , 5α , 6β (S*) ] ] -3, 3-Dimethyl-6- [ [ [ [ [3- (methylsulfonyl) -2-oxo-1-imidazolidinyl] carbonyl] amino] phenylacetyl] amino] -7-oxo-4-thia-1-azabicyclo [3. 2. 0] heptane-2-carboxylic Acid; Mezlin; Mezlocillinum; Mezlocilina; Mezlocilline. Grades: ≥98%. CAS No. 51481-65-3. Molecular formula: C21H25N5O8S2. Mole weight: 539.58.
MGL-3196
MGL-3196 is a first-in-class, orally available, once-daily and liver-directed thyroid hormone receptor (THR) beta-selective agonist. Studies suggest that MGL-3196 has an attractive, differentiated profile as a potential treatment for non-alcoholic steatohepatitis (NASH) and dyslipidemias. Uses: Potential treatment for non-alcoholic steatohepatitis (nash) and dyslipidemias. Synonyms: CHEMBL3261331; UNII-RE0V0T1ES0; MGL-3196; MGL 3196; MGL3196; VIA 3196; VIA3196; VIA-3196; Resmetirom.RE0V0T1ES0; 2-[3,5-dichloro-4-[(6-oxo-5-propan-2-yl-1H-pyridazin-3-yl)oxy]phenyl]-3,5-dioxo-1,2,4-triazine-6-carbonitrile. CAS No. 920509-32-6. Molecular formula: C17H12Cl2N6O4. Mole weight: 435.211.
MI-463
MI-463, a thienopyrimidine derivative, has been found to be a menin inhibitor that could be significant in Leukaemia studies. Synonyms: MI-463; MI 463; MI463; 4-methyl-5-((4-((6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)methyl)-1H-indole-2-carbonitrile. Grades: 98%. CAS No. 1628317-18-9. Molecular formula: C24H23F3N6S. Mole weight: 484.55.