BOC Sciences 8 - Products
BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
Product | Description | |
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Moxifloxacin Impurity S Quick inquiry Where to buy | An impurity of Moxifloxacin, a fourth-generation antibacterial drug. Synonyms: 1-cyclopropyl-7-fluoro-8-methoxy-6-((4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid. Grades: 95% by HPLC. CAS No. 2205053-60-5. Molecular formula: C21H24FN3O4. Mole weight: 401.43. | |
Mozavaptan Quick inquiry Where to buy | Mozavaptan (OPC-31260) inhibits AVP binding to V1 and V2 receptors in a competitive manner. Uses: Antidiuretic hormone receptor antagonists. Synonyms: N-(4-(5-(dimethylamino)-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)phenyl)-2-methylbenzamide; OPC-31260; OPC 31260; OPC31260; Mozavaptan. Grades: >98%. CAS No. 137975-06-5. Molecular formula: C27H29N3O2. Mole weight: 427.54. | |
MPO-IN-28 Quick inquiry Where to buy | MPO-IN-28 is a myeloperoxidase (MPO) inhibitor with IC50 of 44 nM. Synonyms: GNF-Pf-3346; 1-(7-methoxy-4-methylquinazolin-2-yl)guanidine; (7-methoxy-4-methyl-quinazolin-2-yl)-guanidine. CAS No. 37836-90-1. Molecular formula: C11H13N5O. Mole weight: 231.25. | |
MRE-269 Quick inquiry Where to buy | MRE-269 is an orally available and long-acting prostacyclin receptor agonist prodrug used for the treatment of pulmonary arterial hypertension. Uses: Prostacyclin receptor agonist. Synonyms: MRE-269; MRE269; MRE 269; ACT-333679; ACT 333679; ACT333679. [4-[(5,6-diphenylpyrazinyl)(1-methylethyl)amino]butoxy]-acetic acid; 2-[4-[(5,6-Diphenyl-2-pyrazinyl)(1-methylethyl)amino]butoxy]-acetic Acid. Grades: ≥98%. CAS No. 475085-57-5. Molecular formula: C25H29N3O3. Mole weight: 419.5. | |
MRT67307 Quick inquiry Where to buy | This active molecular is a potent ULK1/2 inhibitor and the IC50 value is 2.9 nM and 1.1 nM. MRT68921 is also a SIK inhibitor. Synonyms: MRT67307; MRT 67307; MRT-67307; N- [3- [ [5-cyclopropyl-2- [3- (morpholin-4-ylmethyl) anilino] pyrimidin-4-yl] amino] propyl] cyclobutanecarboxamide, 1190379-70-4 (HCl). Grades: 98%. CAS No. 1190378-57-4. Molecular formula: C26H36N6O2. Mole weight: 464.61. | |
MS023 Quick inquiry Where to buy | MS023 is a Potent, Selective, and Cell-Active Inhibitor of Human Type I Protein Arginine Methyltransferases. MS023 displayed high potency for type I PRMTs including PRMT1, -3, -4, -6, and -8 but was completely inactive against type II and type III PRMTs, protein lysine methyltransferases and DNA methyltransferases. Synonyms: MS023; MS-023; MS 023. Grades: 98%. CAS No. 1831110-54-3. Molecular formula: C17H25N3O. Mole weight: 287.41. | |
MS023 dihydrochloride Quick inquiry Where to buy | MS023 dihydrochloride is a potent, selective and cell-active human type I protein arginine methyltransferases (PRMTs) inhibitor, with IC50s of 30, 119, 83, 4 and 5 nM for PRMT1, PRMT3, PRMT4, PRMT6 and PRMT8, respectively. Synonyms: N1-Methyl-N1-[[4-[4-(1-methylethoxy)phenyl]-1H-pyrrol-3-yl]methyl]-1,2-ethanediamine dihydrochloride; N-{[4-(4-Isopropoxyphenyl)-1H-pyrrol-3-yl]methyl}-N-methyl-1,2-ethanediamine dihydrochloride; 1,2-Ethanediamine, N1-methyl-N1-[[4-[4-(1-methylethoxy)phenyl]-1H-pyrrol-3-yl]methyl]-, hydrochloride (1:2). Grades: ≥95%. CAS No. 1992047-64-9. Molecular formula: C17H27Cl2N3O. Mole weight: 360.32. | |
MS436 Quick inquiry Where to buy | MS436 is a BRD4 bromodomain inhibitor, which exhibits 10-fold selectivity for BRD4(1) over BRD4(2). Synonyms: MS-436; MS 436. Grades: >98%. CAS No. 1395084-25-9. Molecular formula: C18H17N5O3S. Mole weight: 383.42. | |
MSC2530818 Quick inquiry Where to buy | MSC2530818 is a specific and orally available CDK8 inhibitor with an IC50 of 2.6 nM for CDK8. Synonyms: MSC2530818; MSC-2530818; MSC 2530818. [(2S)-2-(4-chlorophenyl)pyrrolidin-1-yl]-(3-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl)methanone; SCHEMBL17514257; s8387; AKOS032946259. CAS No. 1883423-59-3. Molecular formula: C18H17ClN4O. Mole weight: 340.81. | |
MSDC-0160 Quick inquiry Where to buy | MSDC-0160 reduces resistance in the insulin/IGF-1 signaling pathway and restores IGF-1-induced Akt and GSK-3 phosphorylation. Synonyms: Mitoglitazone; CAY10415; 5-[[4-[2-(5-Ethyl-2-pyridinyl)-2-oxoethoxy]phenyl]methyl]-2,4-thiazolidinedione; Pioglitazone Ketone; 5-(4-(2-(5-ethylpyridin-2-yl)-2-oxoethoxy)benzyl)thiazolidine-2,4-dione; 5-{4-[2-(5-ethylpyridin-2-yl)-2-oxoethoxy]benzyl}-1,3-thiazolidine-2,4-dione. Grades: >98%. CAS No. 146062-49-9. Molecular formula: C19H18N2O4S. Mole weight: 370.42. | |
MSDC-0602 Quick inquiry Where to buy | MSDC-0602 is an insulin sensitizer that has the potential to treat diabetes and other inflammatory diseases. It exhibits low affinity for binding and activation of PPAR&gamma. Synonyms: MSDC-0602; MSDC0602; MSDC 0602; 5-{4-[2-(3-Methoxyphenyl)-2-oxoethoxy]benzyl}-1,3-thiazolidine-2,4-dione; 2,4-Thiazolidinedione, 5-[[4-[2-(3-methoxyphenyl)-2-oxoethoxy]phenyl]methyl]-. CAS No. 1133819-87-0. Molecular formula: C19H17NO5S. Mole weight: 371.407. | |
MTDIA Quick inquiry Where to buy | MTDIA is a human 5'-methylthioadenosine phosphorylase (MTAP) inhibitor, which is solely responsible for 5'-methylthioadenosine (MTA) metabolism to permit S-adenosylmethionine salvage. It is used as an anticancer candidate. Synonyms: Methylthio-DADMe-Immucillin A; MT-DADMe-ImmA; (3R,4S)-1-((4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl)-3-hydroxy-4-((methylthio)methyl)pyrrolidin-1-ium. Grades: 98%. CAS No. 653592-04-2. Molecular formula: C13H19N5OS. Mole weight: 294.35. | |
MTDIA hydrochloride Quick inquiry Where to buy | MTDIA is a methylthioadenosine phosphorylase (MTAP) inhibitor. MTAP is responsible for 5'-methylthioadenosine (MTA) metabolism to permit S-adenosylmethionine salvage. Transition-state (TS) analogues of MTAP are in development as anticancer drug candidates and MTDIA is one of these TS analogues. Uses: Anticancer drug candidate. Synonyms: (3R,4S)-1-((4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl)-3-hydroxy-4-((methylthio)methyl)pyrrolidin-1-ium chloride; MTDIA; MTDIA HCl; Methylthio-DADMe-Immucillin A; MT-DADMe-ImmA; MT-DADMe-ImmA HCl. Grades: 98%. CAS No. 1399840-35-7. Molecular formula: C13H20ClN5OS. Mole weight: 329.85. | |
MTIC Quick inquiry Where to buy | MTIC is a metabolite Temozolomide, which is an alkylating drug. Synonyms: 5-(3-Methyl-1-triazeno)imidazole-4-carboxamide. CAS No. 3413-72-7. Molecular formula: C5H8N6O. Mole weight: 168.16. | |
[μ-(7-Hydroxy-3-oxo-3H-phenoxazine-4,6-diyl)]bis(2,2,2-trifluoroacetato-κO)di-mercury Quick inquiry Where to buy | [μ-(7-Hydroxy-3-oxo-3H-phenoxazine-4,6-diyl)]bis(2,2,2-trifluoroacetato-κO)di-mercury is an intermediate in the synthesis of ReAsH-EDT2, which is a membrane-permeable fluorescent probe for labeling tetracysteine sequences in target proteins. Synonyms: [mu-(7-Hydroxy-3-oxo-3H-phenoxazine-4,6-diyl)]bis(2,2,2-trifluoroacetato)dimercury; Mercury, [μ-(7-hydroxy-3-oxo-3H-phenoxazine-4,6-diyl)]bis(2,2,2-trifluoroacetato-κO)di-. Grades: ≥95%. CAS No. 1073288-58-0. Molecular formula: C16H5F6Hg2NO7. Mole weight: 838.38. | |
Mubritinib Quick inquiry Where to buy | Mubritinib, also known as TAK-165, is a protein kinase inhibitor which was under development by Takeda for the treatment of cancer. It completed phase I clinical trials (may be discontinued since 2008). Mubritinib(TAK 165) is a potent EGFR, HER2 and p34cdc2 inhibitor with IC50 of 6 nM and 0.2 μM, respectively. Mubritinib(TAK 165) also inhibits p33cdk2 and p33cdk5. Mubritinib(TAK 165) displays > 4000-fold selectivity over EGFR, FGFR, PDGFR, JAK1 and Src. Mubritinib(TAK 165) exhibits potent antiproliferative effects in ErbB2-overexpressing cancer cell lines (IC50 = 5 nM in BT474 breast cancer cells) and significantly inhibits bladder, breast and prostate cancer xenograft growth in vivo. Synonyms: Mubritinib; TAK165; TAK-165; TAK-165. Grades: 0.98. CAS No. 366017-09-6. Molecular formula: C25H23F3N4O2. Mole weight: 468.48. | |
Mutant EGFR inhibitor Quick inquiry Where to buy | Mutant EGFR inhibitor is a potent and selective mutant EGFR inhibitor extracted from patent WO 2013014448 A1. It inhibits EGFRL858R, EGFRExon 19 deletionand EGFRT790M. Synonyms: MDK3627; MDK 3627; MDK-3627; Mutant EGFR inhibitor. Grades: >98%. CAS No. 1421373-62-7. Molecular formula: C27H30ClN7O2. Mole weight: 520.03. | |
MYBMIM Quick inquiry Where to buy | MYBMIM is a novel peptidomimetic inhibitor. It can inhibit MYB and CREB-binding protein (CBP) in acute myeloid leukemia (AML) cells. Uses: The potential treatment of acute myeloid leukemia (aml). | |
MYCMI-6 Quick inquiry Where to buy | MYCMI-6 is a selective, high affinity inhibitor of MYC-MAX interaction. MYCMI-6 inhibits tumor cell growth in a MYC-dependent manner with IC50 concentrations as low as 0.5?μM, while sparing normal cells. CAS No. 681282-09-7. Molecular formula: C20H19N7O. Mole weight: 373.4. | |
Myrcludex B Quick inquiry Where to buy | Myrcludex B is a drug candidate for the treatment of hepatitis B and D. It is under a phase II clinical trial. Myrcludex B acts by inhibiting the sodium taurocholate cotransporting polypeptide. Synonyms: MyrB; Myrcludex-B; Hepatera; MYR Pharma; Vision7; Bulevirtide. Grades: ≥98%. CAS No. 2012558-47-1. Molecular formula: C248H355N65O72. Mole weight: 5398.95. | |
N 0924 hydrochloride Quick inquiry Where to buy | N 0924 hydrochloride is a dopamine (DA) receptor agonist that is the less active enantiomer of N-0437 in comparison with the opposite (S)-(-)-enantiomer, Rotigotine. Synonyms: N 0924 hydrochloride; N0924 hydrochloride; N-0924 hydrochloride; (6R)-6-[propyl(2-thiophen-2-ylethyl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride. Grades: 99%. CAS No. 125572-92-1. Molecular formula: C19H25NOS.HCl. Mole weight: 351.93. | |
N1-((1S,2R,4S)-2-amino-4-(dimethylcarbamoyl)cyclohexyl)-N2-(5-chloropyridin-2-yl)oxalamide Quick inquiry Where to buy | An impurity of Edoxaban, which is an oral anticoagulant drug and a direct factor Xa inhibitor. Synonyms: Ethanediamide, N-[(1S,2R,4S)-2-amino-4-[(dimethylamino)carbonyl]cyclohexyl]-N'-(5-chloro-2-pyridinyl); Edoxaban Impurity I. Grades: ≥95%. CAS No. 480452-37-7. Molecular formula: C16H22ClN5O3. Mole weight: 367.83. | |
N-(1,3-dioxoisoindolin-4-yl)acetamide Quick inquiry Where to buy | N-(1,3-dioxoisoindolin-4-yl)acetamide is an impurity of Apremilast, which is an oral phosphodiesterase 4 inhibitor used for treating psoriatic arthritis. Synonyms: 3-Acetamidophthalimide; N-(1,3-dioxo-4-isoindolyl)acetamide. CAS No. 6118-65-6. Molecular formula: C10H8N2O3. Mole weight: 204.18. | |
N1,N2-Bis(5-chloropyridin-2-yl)oxalamide Quick inquiry Where to buy | An impurity of Edoxaban, which is an oral anticoagulant drug and a direct factor Xa inhibitor. Synonyms: Ethanediamide, N,N'-bis(5-chloro-2-pyridinyl);N1,N2-Bis(5-chloro-2-pyridinyl)Ethanediamide; Edoxaban Impurity A. Grades: ≥95%. CAS No. 349125-14-0. Molecular formula: C12H8Cl2N4O2. Mole weight: 311.12. | |
N1,N2-Diboc N-[6-[(Aminoiminomethyl)amino]hexyl]-N'-(4-chlorophenyl)-imidodicarbonimidic Diamide Quick inquiry Where to buy | N1,N2-Diboc N-[6-[(Aminoiminomethyl)amino]hexyl]-N'-(4-chlorophenyl)-imidodicarbonimidic Diamide is an intermediate for the synthesis of Chlorhexidine, which is a disinfectant and topical anti-infective agent for reduction of pocket depth in patients with adult periodontitis. Synonyms: Bis(2-methyl-2-propanyl) { (Z) -[ (6-{N'-[N- (4-chlorophenyl) carbamimidoyl]carbamimidamido}hexyl) amino]methylylidene}biscarbamate; Carbamic acid, N, N'- [ (Z) - [ [6- [ [ [ [ [ (4-chlorophenyl) amino] iminomethyl] amino] iminomethyl] amino] hexyl] amino] methylidyne] bis-, bis(1,1-dimethylethyl) ester. Molecular formula: C25H41ClN8O4. Mole weight: 553.10. | |
N1,N2-Di-Nitroso Palbociclib Quick inquiry Where to buy | N1,N2-Di-Nitroso Palbociclib is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C24H27N9O4. Mole weight: 505.54. | |
N1,N4-bis((R)-1-(3-(2-cyano-5-fluorobenzyl)-1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)piperidin-3-yl)succinamide Quick inquiry Where to buy | An impurity of Trelagliptin. Trelagliptin is a pharmaceutical drug used for the treatment of type 2 diabetes. Synonyms: Trelagliptin Impurity O. CAS No. 2087874-94-8. Molecular formula: C40H42F2N10O6. Mole weight: 796.82. | |
N-(1-Naphthyl) Duloxetine Quick inquiry Where to buy | N-(1-Naphthyl) Duloxetine is an impurity of Duloxetine, which is a serotonin-norepinephrine reuptake inhibitor used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, neuropathic pain and central sensitization. Synonyms: Duloxetine Impurity 1. Molecular formula: C28H25NOS. Mole weight: 423.57. | |
N- [ [ [ (1R) -2- (6-Amino-9H-purin-9-yl) -1-methylethoxy] methyl] hydroxyphosphinyl] -D-alanine Quick inquiry Where to buy | An impurity of Tenofovir, which is an acyclic phosphonate nucleotide derivative, could be used in antiviral treatment as an everse transcriptase inhibitor. Synonyms: GS 7160. CAS No. 376633-24-8. Molecular formula: C12H19N6O5P. Mole weight: 358.29. | |
N-2-[2- (2, 2, 2-Trifluoroethoxy) phenoxy]ethylsilodosin Quick inquiry Where to buy | N-2-[2- (2, 2, 2-Trifluoroethoxy) phenoxy]ethylsilodosin is an impurity of Silodosin, which is an α1a-adrenoceptor antagonist. Synonyms: N-2-[2- (2, 2, 2-Trifluoroethoxy) phenoxy]ethylsilodosin; 1453221-45-8; 5-[2-[bis[2-[2- (2, 2, 2-trifluoroethoxy) phenoxy]ethyl]amino]propyl]-1- (3-hydroxypropyl) -2, 3-dihydroindole-7-carboxamide; Silodosin Dimer Impurity; BCP32812; Silodosin impurity 19; N-2-[2- (2, 2, 2-Trifluoroethoxy) phenoxy]ethylsilodosin. CAS No. 1453221-45-8. Molecular formula: C35H41F6N3O6. Mole weight: 713.718. | |
N2-[4-[[ (2, 4-Diamino-6-pteridinyl) methyl]methylamino]benzoyl]-N-[5-[[ (1, 1-dimethylethoxy) carbonyl]amino]pentyl]-L-glutamine 1,1'-Dimethylethyl Ester Quick inquiry Where to buy | N2-[4-[[ (2, 4-Diamino-6-pteridinyl) methyl]methylamino]benzoyl]-N-[5-[[ (1, 1-dimethylethoxy) carbonyl]amino]pentyl]-L-glutamine 1,1'-Dimethylethyl Ester is one of Methotrexate derivatives. Methotrexate is a Folic Acid antagonist, used as an antineoplastic and antirheumatic. Synonyms: L-Glutamine, N2-[4-[[ (2, 4-diamino-6-pteridinyl) methyl]methylamino]benzoyl]-N-[5-[[ (1, 1-dimethylethoxy) carbonyl]amino]pentyl]-, 1,1-dimethylethyl ester. Grades: 98%. CAS No. 1637756-15-0. Molecular formula: C34H50N10O6. Mole weight: 694.82. | |
N-((2-(5-Methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)propionamide Quick inquiry Where to buy | N-((2-(5-Methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)propionamide is an impurity of Parecoxib, which is a selective COX2 inhibitor and a water-soluble and injectable prodrug of valdecoxib. Uses: Cyclooxygenase 2 inhibitors. Synonyms: Propanamide, N-[[2-(5-methyl-3-phenyl-4-isoxazolyl)phenyl]sulfonyl]-. Molecular formula: C19H18N2O4S. Mole weight: 370.42. | |
N-((2-(5-methyl-4-phenylisoxazol-3-yl)phenyl)sulfonyl)propionamide Quick inquiry Where to buy | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Impurity 34. CAS No. 2304623-38-7. Molecular formula: C19H18N2O4S. Mole weight: 370.42. | |
N-(2-Acetylphenyl)-2-(8-bromo-7-(but-2-yn-1-yl)-3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-1-yl)acetamide Quick inquiry Where to buy | An impurity of Linagliptin, a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes. Synonyms: 1H-Purine-1-acetamide, N-(2-acetylphenyl)-8-bromo-7-(2-butyn-1-yl)-2,3,6,7-tetrahydro-3-methyl-2,6-dioxo-; Linagliptin impurity KH-2. Grades: ≥95%. CAS No. 2279114-31-5. Molecular formula: C20H18BrN5O4. Mole weight: 472.29. | |
N-(2-acetylphenyl)-2-chloroacetamide Quick inquiry Where to buy | An impurity of Linagliptin, a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes. Synonyms: Acetamide, N-(2-acetylphenyl)-2-chloro-; Linagliptin Impurity A. Grades: ≥95%. CAS No. 6140-11-0. Molecular formula: C10H10ClNO2. Mole weight: 211.64. | |
N-(2-amino-6-((4-fluorobenzyl)amino)pyridin-3-yl)acetamide Quick inquiry Where to buy | It is an impurity of Flupirtine. Flupirtine is a selective neuronal potassium channel opener that acts as an Analgesic, having substituted pyridine with central analgesic properties. Synonyms: Acetamide, N-[2-amino-6-[[(4-fluorophenyl)methyl]amino]-3-pyridinyl]-; Flupirtine Impurity 04. Grades: 99% by HPLC. CAS No. 91941-04-7. Molecular formula: C14H15FN4O. Mole weight: 274.29. | |
N-(2-Chloro-1-oxopropyl)glycine Quick inquiry Where to buy | N-(2-Chloro-1-oxopropyl)glycine is an impurity of Tiopronin, which is used as an antidote against heavy metal poisoning. Synonyms: N-(2-Chloropropionyl)glycine; Tiopronin Impuriy 1. Grades: 98%. CAS No. 85038-45-5. Molecular formula: C5H8ClNO3. Mole weight: 165.57. | |
N-2-Ethylhexanoyl Cloxacillin Penicilloic Acid Quick inquiry Where to buy | N-2-Ethylhexanoyl Cloxacillin Penicilloic Acid is an impurity of Cloxacillin, which is a semisynthetic beta-lactamase resistant penicillin antibiotic with antibacterial activity used to treat many bacterial infections. Synonyms: (2R,4S)-2-[(S)-Carboxy({[3-(2-chlorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}amino)methyl]-3-(2-ethylhexanoyl)-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid; 2-Thiazolidineacetic acid, 4-carboxy-α-[[[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3-(2-ethyl-1-oxohexyl)-5,5-dimethyl-, (αS,2R,4S)-. Molecular formula: C27H34ClN3O7S. Mole weight: 580.09. | |
N-2-Ethylhexanoyl Cloxacilln Acid Quick inquiry Where to buy | ||
N-(2-Mercapto-1-oxopropyl)-L-alanine Quick inquiry Where to buy | N-(2-Mercapto-1-oxopropyl)-L-alanine is an analog of Tiopronin, which is used as an antidote against heavy metal poisoning. Uses: Tiopronin alanine analog. Synonyms: L-Alanine, N-(2-mercapto-1-oxopropyl)-; N-(2-Sulfanylpropanoyl)-L-alanine; (2S)-2-(2-Mercaptopropanamido)propanoic acid. Grades: 98%. CAS No. 26843-61-8. Molecular formula: C6H11NO3S. Mole weight: 177.22. | |
N-(2-Mercapto-1-oxopropyl)-L-serine Quick inquiry Where to buy | N-(2-Mercapto-1-oxopropyl)-L-serine is a serine analog of Tiopronin, which is used as an antidote against heavy metal poisoning. Synonyms: (2-mercaptopropanoyl)-L-serine; N-(2-Sulfanylpropanoyl)-L-serine; L-Serine, N-(2-mercapto-1-oxopropyl)-; (2S)-3-Hydroxy-2-(2-mercaptopropanamido)propanoic acid. Grades: 98%. CAS No. 1313496-17-1. Molecular formula: C6H11NO4S. Mole weight: 193.22. | |
N-(2-Mercapto-1-oxopropyl)-L-valine Quick inquiry Where to buy | N-(2-Mercapto-1-oxopropyl)-L-valine is a valine analog of Tiopronin, which is used as an antidote against heavy metal poisoning. Synonyms: N-(2-Sulfanylpropanoyl)-L-valine; L-Valine, N-(2-mercapto-1-oxopropyl)-; (2-mercaptopropanoyl)-L-valine; (2S)-2-(2-Mercaptopropanamido)-3-methylbutanoic acid. Grades: 98%. CAS No. 1313496-16-0. Molecular formula: C8H15NO3S. Mole weight: 205.27. | |
N-(2-methyl-4-oxopentan-2-yl)-sulfamethoxazole Quick inquiry Where to buy | An impurity of Sulfamethoxazole, which is an antibiotic and a structural analog of para-aminobenzoic acid (PABA). It competes with PABA to bind to dihydropteroate synthetase to inhibit the synthesis of dihydrofolic acid. Grades: 98.0%. Molecular formula: C16H21N3O4S. | |
N2-Nitroso Palbociclib Quick inquiry Where to buy | N2-Nitroso Palbociclib is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C24H28N8O3. Mole weight: 476.54. | |
N-(2-p-Methoxyphenyl-1-methyl)ethylaspartic Acid Quick inquiry Where to buy | Grades: > 95%. Molecular formula: C14H19NO5. Mole weight: 281.31. | |
N-(2-p-Methoxyphenyl-1-methyl)ethylformamide Quick inquiry Where to buy | N-(2-p-Methoxyphenyl-1-methyl)ethylformamide is an impurity of formoterol. Synonyms: N-[2-(4-Methoxyphenyl)-1-methylethyl]-formamide. Grades: > 95%. CAS No. 126002-14-0. Molecular formula: C11H15NO2. Mole weight: 193.25. | |
N-[(3,4-Dimethoxy-2-pyridinyl)methyl] Pantoprazole Quick inquiry Where to buy | An impurity of Pantoprazole which is a proton pump inhibitor used to treat erosive esophagitis (damage to the esophagus from stomach acid), and other conditions involving excess stomach acid such as Zollinger-Ellison syndrome. Synonyms: 5-(difluoromethoxy)-1-((3,4-dimethoxypyridin-2-yl)methyl)-2-(((3,4-dimethoxypyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole. CAS No. 957470-59-6. Molecular formula: C24H24F2N4O6S. Mole weight: 534.53. | |
N-[(3,4-Dimethoxy-2-pyridinyl)methyl] Pantoprazole Sulfide Quick inquiry Where to buy | An impurity of Pantoprazole which is a proton pump inhibitor used to treat erosive esophagitis (damage to the esophagus from stomach acid), and other conditions involving excess stomach acid such as Zollinger-Ellison syndrome. Synonyms: 5-(Difluoromethoxy)-1-((3,4-dimethoxypyridin-2-yl)methyl)-2-(((3,4-dimethoxypyridin-2-yl)methyl)thio)-1H-benzo[d]imidazole. CAS No. 957470-58-5. Molecular formula: C24H24F2N4O5S. Mole weight: 518.53. | |
N-[[3- (5-Methyl-3-phenyl-4-isoxazolyl) phenyl]sulfonyl]propanamide Quick inquiry Where to buy | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Sodium Impurity 14; Propanamide, N-[[3-(5-methyl-3-phenyl-4-isoxazolyl)phenyl]sulfonyl]-. Grades: ≥95%. CAS No. 1709956-89-7. Molecular formula: C19H18N2O4S. Mole weight: 370.42. | |
N-((3-(5-methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)propionamide Quick inquiry Where to buy | Cas No. 1709956-89-7. | |
N-((3-(5-methyl-4-phenylisoxazol-3-yl)phenyl)sulfonyl)propionamide Quick inquiry Where to buy | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Impurity 20. CAS No. 2229657-81-0. Molecular formula: C19H18N2O4S. Mole weight: 370.42. | |
N-(3-chloro-2-fluorophenyl)-7-methoxy-6-nitro-4-Quinazolinamine Quick inquiry Where to buy | One of the impurities of Dacomitinib. Dacomitinib, aslo known as PF-299 and PF-00299804 or PF299804, is an orally bioavailable, highly selective, second-generation small-molecule inhibitor of the pan-epidermal growth factor receptor (EGFR) family of tyrosine kinases (ErbB family) with potential antineoplastic activity. Synonyms: Dacomitinib Impurity 2F3LXJ. Grades: ≥95%. CAS No. 1454307-45-9. Molecular formula: C15H10ClFN4O3. Mole weight: 348.72. | |
N-(3-Chloro-4-fluorophenyl)-7-ethoxy-6-nitro-4-quinazolinamine Quick inquiry Where to buy | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: Afatinib Impurity YYJX. Grades: ≥95%. CAS No. 1360430-70-1. Molecular formula: C16H12ClFN4O3. Mole weight: 362.74. | |
N-(3-Dimethylaminopropyl)desipramine DiHCl Quick inquiry Where to buy | Impurity of Desipramine HCl. Synonyms: N-[3-(10,11-Dihydro-5H-dibenzo-[b,f]azepin-5-yl)propyl]-N,N',N'-trimethylpropane-1,3-diamine Dihydrochloride. Grades: > 95%. CAS No. 1838-02-4. Molecular formula: C23H33N3ยท2HCl. Mole weight: 424.45. | |
N-[(3R)-3-(2-Methylphenoxy)-3-phenylpropyl]carbamic Acid 1,1-Dimethylethyl Ester Quick inquiry Where to buy | N-[(3R)-3-(2-Methylphenoxy)-3-phenylpropyl]carbamic Acid 1,1-Dimethylethyl Ester is an intermediate in the synthesis of Atomoxetine, which is a selective norepinephrine (NE) reuptake inhibitor for the treatment of attention-deficit hyperactivity disorder (ADHD). Synonyms: Carbamic acid, N-[(3R)-3-(2-methylphenoxy)-3-phenylpropyl]-, 1,1-dimethylethyl ester; 2-Methyl-2-propanyl [(3R)-3-(2-methylphenoxy)-3-phenylpropyl]carbamate. Grades: ≥95%. CAS No. 1191280-19-9. Molecular formula: C21H27NO3. Mole weight: 341.44. | |
N-[4-[[ (2, 4-Diamino-6-pteridinyl) methyl]amino]benzoyl]glutamic Acid Quick inquiry Where to buy | N-[4-[[ (2, 4-Diamino-6-pteridinyl) methyl]amino]benzoyl]glutamic Acid is one of Methotrexate intermediates. Methotrexate is a Folic Acid antagonist, used as an antineoplastic and antirheumatic. Synonyms: Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]amino]benzoyl]-. Grades: ≥95%. CAS No. 1236566-87-2. Molecular formula: C19H20N8O5. Mole weight: 440.41. | |
N-(4-(2-amino-2-oxoethyl)thiazol-2-yl)-2-(2-aminothiazol-4-yl) acetamide Quick inquiry Where to buy | An impurity of Mirabegron. Mirabegron (formerly YM-178, trade name Myrbetriq) is a drug for the treatment of overactive bladder. It was developed by Astellas Pharma and was approved in the United States in July 2012. Mirabegron activates the β3 adrenergic receptor in the detrusor muscle in the bladder, which leads to muscle relaxation and an increase in bladder capacity. Synonyms: 2-(2-(2-(2-Aminothiazol-4-yl)acetamido)thiazol-4-yl)acetic Acid; Mirabegron Impurity 8. CAS No. 2036283-13-1. Molecular formula: C10H10N4O3S2. Mole weight: 298.34. | |
N4-(3-chloro-2-fluorophenyl)-7-methoxy-4,6-quinazolinediamine Quick inquiry Where to buy | One of the impurities of Dacomitinib. Dacomitinib, aslo known as PF-299 and PF-00299804 or PF299804, is an orally bioavailable, highly selective, second-generation small-molecule inhibitor of the pan-epidermal growth factor receptor (EGFR) family of tyrosine kinases (ErbB family) with potential antineoplastic activity. Synonyms: Dacomitinib Impurity 2F3LAJ. Grades: ≥95%. CAS No. 1221892-23-4. Molecular formula: C15H12ClFN4O. Mole weight: 318.73. | |
N4-(3-Chloro-4-Fluorophenyl)-7-Methoxyquinazoline-4,6-Diamine Quick inquiry Where to buy | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-aminoquinazolin-4-amine; 4,6-Quinazolinediamine, N4-(3-chloro-4-fluorophenyl)-7-methoxy-; Afatinib Impurity JYJ-2. Grades: ≥95%. CAS No. 179552-75-1. Molecular formula: C15H12ClFN4O. Mole weight: 318.73. | |
N-[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-3-cyano-7-ethoxyquinolin-6-yl]formamide Quick inquiry Where to buy | An impurity of Neratinib, which is an irreversible inhibitor of the HER-2 receptor tyrosine kinase with potential antineoplastic activity. Synonyms: Formamide, N-[4-[[3-chloro-4-(2-pyridinylmethoxy)phenyl]amino]-3-cyano-7-ethoxy-6-quinolinyl]-; Neratinib Impurity AJJX. Grades: ≥95%. CAS No. 1144516-20-0. Molecular formula: C25H20ClN5O3. Mole weight: 473.91. | |
N-((4-(3-methyl-5-phenylisoxazol-4-yl)phenyl)sulfonyl)propionamide Quick inquiry Where to buy | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Propanamide, N-[[4-(3-methyl-5-phenyl-4-isoxazolyl)phenyl]sulfonyl]-; Parecoxib Impurity 42. Grades: 98%. CAS No. 477594-28-8. Molecular formula: C19H18N2O4S. Mole weight: 370.42. | |
N-(4-(4-fluorophenyl)-5-formyl-6-isopropylpyrimidin-2-yl)-2-hydroxy-N,2-dimethylpropane-1-sulfonamide Quick inquiry Where to buy | An impurity of Rosuvastatin. Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Synonyms: 1-Propanesulfonamide, N-[4-(4-fluorophenyl)-5-formyl-6-(1-methylethyl)-2-pyrimidinyl]-2-hydroxy-N,2-dimethyl-; Rosuvastatin Impurity 37. Grades: >95%. CAS No. 2101546-09-0. Molecular formula: C19H24FN3O4S. Mole weight: 409.48. | |
N-[[4- (5-Methyl-3-phenyl-4-isoxazolyl) phenyl]sulfonyl]butanamide Quick inquiry Where to buy | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Butanamide, N-[[4-(5-methyl-3-phenyl-4-isoxazolyl)phenyl]sulfonyl]-; Parecoxib Impurity H. Grades: ≥95%. CAS No. 198470-91-6. Molecular formula: C20H20N2O4S. Mole weight: 384.45. | |
N-((4-(5-Methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)acetamide Quick inquiry Where to buy | An impurity of Valdecoxib. Valdecoxib is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, rheumatoid arthritis, etc. Valdecoxib exhibits a selectively inhibitory effect of cyclooxygenase-2. Synonyms: N-[[4-(5-methyl-3-phenylisoxazol-4-yl)phenyl]sulfonyl]acetamide. CAS No. 198471-06-6. Molecular formula: C18H16N2O4S. Mole weight: 356.4. | |
N-((4-(5-methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)butyramide Quick inquiry Where to buy | Cas No. 198470-91-6. | |
N-((4-(5-methyl-4-phenylisoxazol-3-yl)phenyl)sulfonyl)propionamide Quick inquiry Where to buy | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Propanamide, N-[[4-(5-methyl-4-phenyl-3-isoxazolyl)phenyl]sulfonyl]-; Parecoxib Impurity 21. CAS No. 2235371-89-6. Molecular formula: C19H18N2O4S. Mole weight: 370.42. | |
N-(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)-N-phenylcyclopropane-1,1-dicarboxamide Quick inquiry Where to buy | It is an impurity of Cabozantinib. Cabozantinib is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively. Synonyms: 1,1-Cyclopropanedicarboxamide, N-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N'-phenyl-; Cabozantinib Impurity 02. CAS No. 849221-94-9. Molecular formula: C28H25N3O5. Mole weight: 483.52. | |
N-(4-fluorophenyl)-N-(4-((6-hydroxy-7-methoxyquinolin-4-yl)oxy)phenyl)cyclopropane-1,1-dicarboxamide Quick inquiry Where to buy | It is an impurity of Cabozantinib. Cabozantinib is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively. Synonyms: 1,1-Cyclopropanedicarboxamide, N-(4-fluorophenyl)-N'-[4-[(7-hydroxy-6-methoxy-4-quinolinyl)oxy]phenyl]-; Cabozantinib Impurity 06. CAS No. 1628530-42-6. Molecular formula: C27H22FN3O5. Mole weight: 487.48. | |
N-(4-fluorophenyl)-N-(4-((7-hydroxy-6-methoxyquinolin-4-yl)oxy)phenyl)cyclopropane-1,1-dicarboxamide Quick inquiry Where to buy | It is an impurity of Cabozantinib. Cabozantinib is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively. Synonyms: 1,1-Cyclopropanedicarboxamide, N-(4-fluorophenyl)-N'-(4-((6-hydroxy-7-methoxy-4-quinolinyl)oxy)phenyl)-; Dimethyl cabozantinib; Cabozantinib Impurity 05. Grades: 99% by HPLC. CAS No. 1628530-47-1. Molecular formula: C27H22FN3O5. Mole weight: 487.48. | |
N4-Hydroxymethyl Hydrochlorothiazide Quick inquiry Where to buy | An impurity of Hydrochlorothiazide, a diuretic medication used for the treatment of high blood pressure. Synonyms: 6-chloro-4-(hydroxymethyl)-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide 1,1-dioxide. CAS No. 1216599-78-8. Molecular formula: C8H10ClN3O5S2. Mole weight: 327.77. |