BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Linagliptin N-Acetyl Impurity | An impurity of Linagliptin. Linagliptin is a dipeptidyl peptidase-4 inhibitor with a hpyerglycemic activity. It was approved for the treatment of diabetes mellitus type 2. Synonyms: (R)-N-(1-(7-(But-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)acetamide. Grades: 95%. CAS No. 1803079-49-3. Molecular formula: C27H30N8O3. Mole weight: 514.58. |  |
| Linagliptin N-Boc Impurity | An impurity of Linagliptin. Linagliptin is a dipeptidyl peptidase-4 inhibitor with a hpyerglycemic activity. It was approved for the treatment of diabetes mellitus type 2. Synonyms: Linagliptin Related Compound B, N-[(3R)-1-[7-(2-butyn-1-yl)-2,3,6,7-tetrahydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-2,6-dioxo-1H-purin-8-yl]-3-piperidinyl]-carbamic Acid 1,1-Dimethylethyl Ester. Grades: 95%. CAS No. 668273-75-4. Molecular formula: C30H36N8O4. Mole weight: 572.67. | |
| Linagliptin N-Formyl Impurity | An impurity of Linagliptin, a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes. Synonyms: Linagliptin Impurity JX; (R)-N-(1-(7-(But-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)formamide. Grades: ≥95%. CAS No. 2137744-33-1. Molecular formula: C26H28N8O3. Mole weight: 500.55. | |
| Lincomycin 2-Phosphate | Lincomycin 2-Phosphate (Clindamycin Phosphate EP Impurity F) is an impurity of Clindamycin, which is a semi-synthetic antibiotic prepared from Lincomycin. Synonyms: Methyl 6,8-dideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-D-erythro-α-D-galacto-Octopyranoside 2-(dihydrogen phosphate); Clindamycin Phosphate EP Impurity F. Grades: 95%. CAS No. 27480-30-4. Molecular formula: C18H35N2O9PS. Mole weight: 486.52. | |
| Linear Daptomycin | Daptomycin Lactone Hydrolysis is an impurity of Daptomycin, which is a lipopeptide antibiotic used to treat systemic infections and life-threatening infections caused by gram-positive organisms. Synonyms: N-decanoyl-L-tryptophyl-D-asparginyl-L-aspartyl-L-threonylglycyl-L-ornithyl-L-aspartyl-D-alanyl-L-aspartylglycyl-D-serylthreo-3-methyl-L-glutamyl-3-anthraniloyl-L-alanine; decanoyl-Trp-D-Asn-Asp-Thr-Gly-Orn-Asp-D-Ala-Asp-Gly-D-Ser-Glu(3R-Me)-Asp(Ph(2-NH2))-OH; (2S,5S,8R,14S,17R,20S,23S,29S,32S)-32-((R)-4-amino-2-((S)-2-decanamido-3-(1H-indol-3-yl)propanamido)-4-oxobutanamido)-2-(2-(2-aminophenyl)-2-oxoethyl)-23-(3-aminopropyl)-14,20-bis(carboxymethyl)-5-((R)-1-carboxypropan-2-yl)-29-((R)-1-hydroxyethyl)-8-(hydroxymethyl)-17-methyl-4,7,10,13,16,19,22,25,28,31-decaoxo-3,6,9,12,15,18,21,24,27,30-decaazatetratriacontanedioic acid; Benzenebutanoic acid, N-(1-oxodecyl)-L-tryptophyl-D-asparaginyl-L-α-aspartyl-L-threonylglycyl-L-ornithyl-L-α-aspartyl-D-alanyl-L-α-aspartylglycyl-D-seryl-(3R)-3-methyl-L-α-glutamyl-α,2-diamino-γ-oxo-, (αS)-; (αS)-N-(1-Oxodecyl)-L-tryptophyl-D-asparaginyl-L-α-aspartyl-L-threonylglycyl-L-ornithyl-L-α-aspartyl-D-alanyl-L-α-aspartylglycyl-D-seryl-(3R)-3-methyl-L-α-glutamyl-α,2-diamino-γ-oxobenzenebutanoic acid; Daptomycin Lactone Hydrolysis. CAS No. 883991-21-7. Molecular formula: C72H103N17O27. Mole weight: 1638.71. | |
| Linear octreotide | Linear octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: D-phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cystyl-L-threoninol; Octreotide Impurity-A; L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-; D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-L-cysteinamide; Octreotide (reduced); D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr-ol. CAS No. 205652-45-5. Molecular formula: C49H68N10O10S2. Mole weight: 1021.26. | |
| Linezolid Desacetamide Phthalimide | Linezolid Desacetamide Phthalimide is a Linezolid intermediate. Synonyms: (S)-N-[[3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]phthalimide; (S)-2-[[3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-1H-isoindole-1,3(2H)-dione; 2-[[(5S)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]. Grades: > 95%. CAS No. 168828-89-5. Molecular formula: C22H20FN3O5. Mole weight: 425.41. | |
| Linezolid Dimer | Linezolid Dimer is an impurity of the antibacterial agent Linezolid. Synonyms: N,N-bis[[(5S)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide; Bis(linezolid); Bis-Linezolid; Linezolid Impurity D. Grades: > 95%. CAS No. 908143-04-4. Molecular formula: C30H35F2N5O7. Mole weight: 615.62. | |
| Linezolid Impurity 10 | Grades: > 95%. Molecular formula: C17H24FN3O4. Mole weight: 353.40. | |
| Linezolid Impurity 11 | N-t-Butyl N-Deactyl Linezolid is a derivative of Linezolid, a prototype of the oxazolidinone antimicrobials. Synonyms: N-t-Butyl N-Deactyl Linezolid; (5S)-5-[[(1,1-Dimethylethyl)amino]methyl]-3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxazolidinone. Grades: > 95%. CAS No. 1215006-08-8. Molecular formula: C18H26FN3O3. Mole weight: 351.42. | |
| Linezolid Impurity 12 | N-t-Butyl Linezolid is a derivative of Linezolid, prototype of the oxazolidinone antimicrobials. Synonyms: N-t-Butyl Linezolid; (S)-N-(tert-Butyl)-N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide. Grades: > 95%. CAS No. 1215006-11-3. Molecular formula: C20H28FN3O4. Mole weight: 393.45. | |
| Linezolid Impurity 13 (PNU142300) | PNU 142300 is an inactive metabolite of Linezolid. Synonyms: N-[4-[(5S)-5-[(Acetylamino)methyl]-2-oxo-3-oxazolidinyl]-2-fluorophenyl]-N-(2-hydroxyethyl)glycine. Grades: > 95%. CAS No. 368891-69-4. Molecular formula: C16H20FN3O6. Mole weight: 369.34. | |
| Linezolid Impurity 15 | Grades: > 95%. Molecular formula: C15H20FN3O2. Mole weight: 293.34. | |
| Linezolid Impurity 16 | Linezolid Dipthalimide is an impurity in the synthesis of Linezolid, a prototype of the oxazolidinone antimicrobials. It inhibits bacterial mRNA translation. Synonyms: Linezolid Diphthalimide; 2,2'-(3,3'-(3-Fluoro-4-morpholinophenylazanediyl)bis(2-hydroxypropane-3,1-diyl))diidoindoline-1,3-dione. Grades: > 95%. CAS No. 1798014-14-8. Molecular formula: C32H31FN4O7. Mole weight: 602.61. | |
| Linezolid Impurity 17 | Grades: > 95%. Molecular formula: C13H20FN3O2. Mole weight: 269.32. | |
| Linezolid Impurity ((5R)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-5-hydroxymethyl-2-oxazolidinone) | [(R)-3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl]methanol is an intermediate in the synthesis of Linezolid Dimer, an impurity of the antibacterial agent Linezolid. Synonyms: [(R)-3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl]methanol; (R)-5-(Hydroxymethyl)-3-(3-fluoro-4-morpholinophenyl)oxazolidin-2-one; (R)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-5-(hydroxymethyl)-2-oxazolidinone. Grades: > 95%. CAS No. 168828-82-8. Molecular formula: C14H17FN2O4. Mole weight: 296.30. | |
| Linezolid Impurity 8 | Grades: > 95%. CAS No. 868405-66-7. Molecular formula: C13H18ClFN2O2. Mole weight: 288.75. | |
| Linezolid Impurity 9 | Grades: > 95%. CAS No. 1634630-28-6. Molecular formula: C13H17FN2O2. Mole weight: 252.29. | |
| Linezolid Impurity D HCl | N-[(2S)-3-Amino-2-hydroxypropyl]-N-[3-fluoro-4-(4-morpholinyl)phenyl]acetamide is one of the major thermal degradation products of Linezolid. Synonyms: N-[(2S)-3-Amino-2-hydroxypropyl]-N-[3-fluoro-4-(4-morpholinyl)phenyl] acetamide Hydrochloride. Grades: > 95%. CAS No. 1391068-25-9. Molecular formula: C15H23ClFN3O3. Mole weight: 347.81. | |
| Linezolid Impurity (N,O-Desethylene Linezolid) | N,O-Desethylene Linezolid is a potential drug metabolite of Linezolid used as an antibiotic. N,O-Desethylene Linezolid was identified as Linezolid impurity. Synonyms: N-[[(5S)-3-[3-Fluoro-4-[(2-hydroxyethyl)amino]phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide. Grades: > 95%. CAS No. 1219708-30-1. Molecular formula: C14H18FN3O4. Mole weight: 311.31. | |
| Linezolid impurity PNU177636 | Grades: > 95%. Molecular formula: C20H26FN3O5. Mole weight: 407.45. | |
| Linezolid related Compound | Cas No. 174649-09-3. | |
| Linezolid Related Compound A | Deacetamide Linezolid Azide is an impurity of Linezolid, as antimycobacterial agent. Synonyms: Deacetamide Linezolid Azide; (5R)-5-(Azidomethyl)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxazolidinone; (R)-5-(Azidomethyl)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxazolidinone. Grades: > 95%. CAS No. 168828-84-0. Molecular formula: C14H16FN5O3. Mole weight: 321.31. | |
| Linezolid Related Impurity 2 HCl | Grades: > 95%. Molecular formula: C15H23ClFN3O3. Mole weight: 347.82. | |
| Linifanib | Description of Linifanib: Linifanib is an orally bioavailable, small-molecule receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity. Linifanib inhibits members of the vascular endothelial growth factor (VEGF) and platelet-derived growth factor (PDGF) receptor families; it exhibits much less activity against unrelated RTKs, soluble tyrosine kinases, or serine/threonine kinases. This agent does not have a general antiproliferative effect due to its high dose requirement. However, linifanib may exhibit potent antiproliferative and apoptotic effects on tumor cells whose proliferation is dependent on mutant kinases, such as fms-related tyrosine kinase receptor-3 (FLT3). Synonyms: ABT869; ABT 869; ABT-869; Linifanib. CAS No. 796967-16-3. Molecular formula: C21H18FN5O. Mole weight: 375.407. | |
| Linolenyl alcohol | Synonyms: (9Z,12Z,15Z)-9,12,15-Octadecatrien-1-ol; 9,12,15-Octadecatrien-1-ol, (9Z,12Z,15Z)-. Grades: 95%. CAS No. 506-44-5. Molecular formula: C18H32O. Mole weight: 264.45. | |
| Liothyronine Sodium | Liothyronine Sodium is the most potent form of thyroid hormone acting on the body to increase the basal metabolic rate, affect protein synthesis. Synonyms: Cytomel; Triostat; 3,3',5-Triiodo-L-Thyronine Sodium Salt. Grades: ≥ 98% (HPLC). CAS No. 55-06-1. Molecular formula: C15H12I3NO4.Na. Mole weight: 672.96. | |
| Liproxstatin-1 | Liproxstatin-1 is a potent ferroptosis inhibitor. Grades: >98%. CAS No. 950455-15-9. Molecular formula: C19H21ClN4. Mole weight: 340.85. | |
| Liquid crystal mixture E7 | Synonyms: [1,1':4',1''-Terphenyl]-4-carbonitrile, 4''-pentyl-, mixt. with 4'-heptyl[1,1'-biphenyl]-4-carbonitrile, 4'-(octyloxy)[1,1'-biphenyl]-4-carbonitrile and 4'-pentyl[1,1'-biphenyl]-4-carbonitrile; 4''-Pentyl-[1,1':4',1''-terphenyl]-4-carbonitrile compound with 4'-(octyloxy)-[1,1'-biphenyl]-4-carbonitrile and 4'-heptyl-[1,1'-biphenyl]-4-carbonitrile and 4'-pentyl-[1,1'-biphenyl]-4-carbonitrile; [1,1'-Biphenyl]-4-carbonitrile, 4'-(octyloxy)-, mixt. contg.; [1,1'-Biphenyl]-4-carbonitrile, 4'-heptyl-, mixt. contg.; [1,1'-Biphenyl]-4-carbonitrile, 4'-pentyl-, mixt. contg.; BDH Liquid Crystal E 7; BDH-E 7; BL 001; E 20 (liquid crystal); E 7 (liquid crystal); GR 63; Licrilite E 7; Lixon GR 63; Merck E 7; Merck NLC-E7; Ro TN 570. Grades: 99.5% (5CB:7CB:8OCB:5CT=51:25:16:8). CAS No. 63748-28-7. Molecular formula: C24H23N.C21H25NO.C20H23N.C18H19N. Mole weight: 1159.63. | |
| Liraglutide | Liraglutide is the long-acting analogue of glucagon-like peptide-1 (GLP-1) receptor which could protect b-cells from apoptosis under conditions associated with the development of type 1 and type 2 diabetes. Synonyms: L-Histidyl-L-alanyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[N-(1-oxohexadecyl)-L-γ-glutamyl]-L-lysyl-L-α-glutamyl-L-pheny. Grades: > 95%. CAS No. 204656-20-2. Molecular formula: C172H265N43O51. Mole weight: 3751.20. | |
| Lixisenatide | Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist that can be used in the treatment of type 2 diabetes mellitus (T2DM). Synonyms: ZP-10(Des-Pro38)-Exendin-4-(Lys)6, amide; ZP10A peptide; His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Ser-Lys-Lys-Lys-Lys-Lys-Lys-NH2; L-histidyl-glycyl-L-alpha-glutamyl-glycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-leucyl-L-seryl-L-lysyl-L-glutaminyl-L-methionyl-L-alpha-glutamyl-L-alpha-glutamyl-L-alpha-glutamyl-L-alanyl-L-valyl-L-arginyl-L-leucyl-L-phenylalanyl-L-isoleucyl-L-alpha-glutamyl-L-tryptophyl-L-leucyl-L-lysyl-L-asparagyl-glycyl-glycyl-L-prolyl-L-seryl-L-seryl-glycyl-L-alanyl-L-prolyl-L-prolyl-L-seryl-L-lysyl-L-lysyl-L-lysyl-L-lysyl-L-lysyl-L-lysinamide; AQVE-10010; Des-38-proline-exendine-4 (Heloderma suspectum)-(1-39)-peptidylpenta-L-lysyl-L-lysinamide. Grades: ≥95%. CAS No. 320367-13-3. Molecular formula: C215H347N61O65S. Mole weight: 4858.48. | |
| LKB1/AAK1 dual inhibitor | LKB1/AAK1 dual inhibitor is an effective inhibitor against multi-kinase especially Pim-1 kinase, which has been newly found to be highly expressed in sorts of isolated human cancer cells. Kd: 35 nM/53 nM/75 nM/380 nM for Pim1/AKK1/MST2/LKB1. Synonyms: LKB1/AAK1 dual inhibitor; MDK-2275; MDK 2275; MDK2275; Pim1/AKK1-IN-1; N-[5-(4-Cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-3-pyridinecarboxamide; Pim1 AKK1-IN-1. Grades: 98%. CAS No. 1093222-27-5. Molecular formula: C20H13N5O. Mole weight: 339.35. | |
| LL-37, Human | LL-37 is a cationic and α-helical antimicrobial peptide. It can inhibit growth of Gram-positive E. coli D21 and Gram-negative B. megatarium in a concentration-dependent manner. LL-37 can promote wound healing following skin-targeted electroporation of a plasmid encoding hCAP-18/LL-37 in mice. Synonyms: LL 37; LL37; L-leucyl-L-leucyl-glycyl-L-alpha-aspartyl-L-phenylalanyl-L-phenylalanyl-L-arginyl-L-lysyl-L-seryl-L-lysyl-L-alpha-glutamyl-L-lysyl-L-isoleucyl-glycyl-L-lysyl-L-alpha-glutamyl-L-phenylalanyl-L-lysyl-L-arginyl-L-isoleucyl-L-valyl-L-glutaminyl-L-arginyl-L-isoleucyl-L-lysyl-L-alpha-aspartyl-L-phenylalanyl-L-leucyl-L-arginyl-L-asparagyl-L-leucyl-L-valyl-L-prolyl-L-arginyl-L-threonyl-L-alpha-glutamyl-L-serine; H-Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser-OH; Cathelicidin; Bac4; Cap-18. Grades: 98%. CAS No. 154947-66-7. Molecular formula: C205H340N60O53. Mole weight: 4493.25. | |
| LM 10 | LM 10 is a selective TDO inhibitor (IC50 values are 0.62 and 2 μM for human and mouse TDO, respectively). Synonyms: LM10; LM 10; LM-10. 6-Fluoro-3-[(1E)-2-(2H-tetrazol-5-yl)ethenyl]-1H-indole. Grades: > 98%. CAS No. 1316695-35-8. Molecular formula: C11H8FN5. Mole weight: 229.21. | |
| LMP744 hydrochloride | LMP744, also known as NSC706744, is a novel indenoisoquinoline topoisomerase I inhibitor. Uses: Topoisomerase i inhibitors. Synonyms: LMP744; LMP 744; LMP-744; 6-(3-(2-hydroxyethyl)amino-1-propyl)-5,6-dihydro-2,3-dimethoxy-8,9-methylenedioxy-5,11-dioxo-11H-indeno(1,2-)isoquinoline; MJ-III-65; NSC 706744; NSC-706744; NSC706744; uglysy8 cpd. CAS No. 308246-57-3. Molecular formula: C24H24N2O7. Mole weight: 452.46. | |
| L-Nal-Lanreotide | L-Nal-Lanreotide is an impurity of Lanreotide, which is a somatostatin analogue with antineoplastic activity. Synonyms: L-2-naphthylalanyl-L-cystyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cycstyl-Threoninamide (Disulfide bridge between cysteines); L-2Nal-Cys-Tyr-D-Trp-Lys-Val-Cys-Thr-NH2 (Disulfide bridge between cysteines); Lanreotide impurity-G; 3-(2-naphthyl)-L-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-L-threoninamide (2->7)-disulfide; H-2Nal-Cys-Tyr-D-Trp-Lys-Val-Cys-Thr-NH2 (Disulfide bridge: Cys2-Cys7). Molecular formula: C54H69N11O10S2. Mole weight: 1096.33. | |
| Lobeline EP Impurity A HCl | An impurity of Lobeline, a pyridine alkaloid found in a variety of plants, particularly those in the genus Lobelia. Synonyms: Lobeline EP Impurity A. Grades: > 95%. CAS No. 731823-86-2. Molecular formula: C22H28ClNO2. Mole weight: 373.92. | |
| Lobenzarit disodium | Lobenzarit disodium is an immunomodulator commonly used for the treatment of arthritis. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: Lobenzarit sodium; Lobenzarit disodium salt; Disodium 4-chloro-2,2'-iminobenzoate; disodium 2-(2-carboxylatoanilino)-4-chlorobenzoate. Grades: >98%. CAS No. 64808-48-6. Molecular formula: C14H8ClNNa2O4. Mole weight: 335.651. | |
| Lobucavir | Lobucavir is a nucleoside analog used in the treatment of viral infections, including those caused by human immunodeficiency virus, cytomegalovirus, and herpes virus. Uses: Cytomegalovirus infections; hepatitis b; herpes simplex virus infections; herpes zoster. Synonyms: 2-Amino-9-[(1R,2R,3S)-2,3-bis(hydroxymethyl)cyclobutyl]-1,9-dihydro-6H-purin-6-one; [1R-(1α,2β,3α)]-2-Amino-9-[2,3-bis(hydroxymethyl)cyclobutyl]-1,9-dihydro-6H-purin-6-one; (+)-Cyclobut G; BMS 180194; SQ 34514. Grades: > 95%. CAS No. 127759-89-1. Molecular formula: C11H15N5O3. Mole weight: 265.27. | |
| Lodoxamide tromethamine | Lodoxamide is a GPR35 agonist that has been used as a mast cell stabilizer. It can be used for topical administration into eyes indicated for allergic symptom treatment. Synonyms: Alomide; Lodoxamidetromethamine. CAS No. 63610-09-3. Molecular formula: C19H28ClN5O12. Mole weight: 553.9. | |
| lofepramine hydrochloride | Lofepramine is a tricyclic antidepressant (TCA) indicated for the treatment of depression. It functions via inhibiting 5-HT and NA reuptake. Synonyms: N-(4-CHLOROBENZOYLMETHYL)-3-(10,11-DIHYDRO-5H-DIBENZ[B,F]AZEPIN-5-YL)-N-METHYLPROPYLAMINE HYDROCHLORIDE; LOFEPRAMINE HCL; LOFEPRAMINE HYDROCHLORIDE; 4'-chloro-2-((3-(10,11-dihydro-5h-dibenz(b,f)azepin-5-yl)propyl)methylamino); acetophenone,4'-chloro-2-((3-(1. Grades: 95%. CAS No. 26786-32-3. Molecular formula: C26H28Cl2N2O. Mole weight: 455.426. | |
| Loflucarban | Loflucarban is an antifungal agent. Synonyms: Loflucarban; NSC 76851; NSC-76851; NSC76851; Fluonilid; Fluonilide; 3,5-Dichloro-4'-fluorothiocarbanilide; 1-(3,5-dichlorophenyl)-3-(4-fluorophenyl)thiourea. CAS No. 790-69-2. Molecular formula: C13H9Cl2FN2S. Mole weight: 315.187. | |
| Lomerizine Dihydrochloride | Lomerizine dihydrochloride, an L- and T-type voltagegated calcium channel blocker, is a selective cerebral vasodilator and antimigraine. Uses: Calcium channel blockers. Synonyms: KB-2796; 1-(2,3,4-Trimethoxybenzyl)-4-(bis(4-fluorophenyl)methyl)piperazine dihydrochloride; Terranas; Piperazine, 1-[bis(4-fluorophenyl)methyl]-4-[(2,3,4-trimethoxyphenyl)methyl]-, hydrochloride (1:2); KB 2796; KB2796. Grades: >98%. CAS No. 101477-54-7. Molecular formula: C27H30F2N2O3.2HCl. Mole weight: 541.46. | |
| Lomitapide | Lomitapide is a potent microsomal triglyceride transfer protein (MTP) inhibitor, used in the treatment of familial hypercholesterolemia. Uses: The treatment of familial hypercholesterolemia. Synonyms: Juxtapid; Lojuxta; AEGR 733; AEGR-733; AEGR733; BMS-201038. Grades: > 98%. CAS No. 182431-12-5. Molecular formula: C39H37F6N3O2. Mole weight: 693.734. | |
| Lomustine | Lomustine (420 μM) triggers apoptosis through the mitochondrial pathway via decrease in the level of the anti-apoptosis proteins Bcl-2 and Bcl-xl, respectively. Uses: Antineoplastic agents, alkylating. Synonyms: nsc79037; nsc 79037; nsc-79037. Grades: >98%. CAS No. 13010-47-4. Molecular formula: C9H16ClN3O2. Mole weight: 233.7. | |
| Lonafarnib | Lonafarnib is a farnesyl transferase inhibitor. Structurely, it is also a synthetic tricyclic derivative of carboxamide with antineoplastic properties. Lonarfanib binds to and inhibits farnesyl transferase, an enzyme involved in the post-translational modification and activation of Ras proteins. Ras proteins participate in numerous signalling pathways (proliferation, cytoskeletal organization), and play an important role in oncogenesis. Mutated ras proteins have been found in a wide range of human cancers. Uses: Enzyme inhibitors. Synonyms: SCH 66336; SCH-66336; SCH66336; Sarasar. Grades: > 95%. CAS No. 193275-84-2. Molecular formula: C27H31Br2ClN4O2. Mole weight: 638.829. | |
| Loratadine Epoxide N-Oxide | Loratadine Epoxide N-Oxide is one of loratadine impurities. Loratadine is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Synonyms: 8-chloro-1''-(ethoxycarbonyl)-5, 6-dihydrodispiro[benzo[5, 6]cyclohepta[1, 2-b]pyridine-11, 2'-oxirane-3', 4''-piperidine] 1-oxide. CAS No. 1432057-93-6. Molecular formula: C22H23ClN2O4. Mole weight: 414.88. | |
| Lorlatinib | Lorlatinib is an ATP-competitive ROS1/ALK inhibitor with potential antitumor activity. Lorlatinib binds to both ALK and ROS1 kinases, resulting in disruption of ALK- and ROS1-mediated signaling and inhibition of ALK- and ROS1-overexpressing tumor cells. Synonyms: PF06463922; PF 06463922; PF-06463922; PF-6463922; PF6463922; PF 6463922; Loratinib. Grades: ≥98%. CAS No. 1454846-35-5. Molecular formula: C21H19FN6O2. Mole weight: 406.421. | |
| L-Ornithine | L-Ornithine is a naturally occurring amino acid playing a key role in the urea cycle. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: Ornithine; (S)-2,5-Diaminopentanoic acid; (S)-Ornithine; (2S)-2,5-diaminopentanoic acid. Grades: 95%. CAS No. 70-26-8. Molecular formula: C5H12N2O2. Mole weight: 132.163. | |
| Losartan Carboxylic Acid | EXP-3174, also known as Losartan Carboxylic Acid, is a physiologically active metabolite of losartan, produced by cytochrome P450 isoforms in the liver. It is an angiotensin II receptor type 1 (AT1) antagonist. The Ki values are 0.97, 0.57, 0.67 nM for rat AT1B/AT1A and human AT1, respectively. Uses: Anti-arrhythmia agents. Synonyms: EXP-3174; EXP 3174; EXP3174; E-3174; E 3174; E3174; Losartan Carboxylic Acid. Grades: 98%. CAS No. 124750-92-1. Molecular formula: C22H21ClN6O2. Mole weight: 436.89. | |
| Losmapimod | Losmapimod is a promising new agent against cardiovascular diseases. This drug works by inhibiting p38 MAP kinases, which play an important role in the development of atherosclerosis and heart failure caused by ischemic conditions. Losmapimod did not cause an improvement in exercise tolerance or lung function, despite being well-tolerated in this COPD population. The p38 MAPK inhibitor losmapimod (GW856553) attenuates the pro-inflammatory response in humans by reducing PIC production. Synonyms: Losmapimod; GW856553; GW-856553; GW 856553 GSK-AHAB; GW856553X; 6-[5-(cyclopropylcarbamoyl)-3-fluoro-2-methylphenyl]-N-(2,2-dimethylpropyl)pyridine-3-carboxamide. Grades: 98%. CAS No. 585543-15-3. Molecular formula: C22H26FN3O2. Mole weight: 383.467. | |
| Loteprednol Etabonate | Loteprednol etabonate is an anti-inflammatory corticosteroid used in ophthalmology. Synonyms: ONO-2235; ONO2235; ONO2235; Loteprednol Etabonate; Lotemax; Alrex; HGP-1; Loterox; Locort. Grades: >98%. CAS No. 82034-46-6. Molecular formula: C24H31ClO7. Mole weight: 466.95. | |
| Loteprednol Etabonate Ethyl Ester | Cas No. 182068-96-8. | |
| Lotilaner | Lotilaner is an insecticide and veterinary drug. It acts as a non-competitive antagonist of insects GABA receptors. Uses: An insecticide and veterinary drug. Synonyms: (S)-3-methyl-N-(2-oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)-5-(5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)thiophene-2-carboxamide. Grades: 98%. CAS No. 1369852-71-0. Molecular formula: C20H14Cl3F6N3O3S. Mole weight: 569.75. | |
| Loxoprofen Related Compound 2 (Mixture of Diastereomers) | An impurity of Loxoprofen, a non-selective nonsteroidal anti-inflammatory drug (NSAID) that has been effective in reducing atherosclerosis in mice by reducing inflammation. Synonyms: 2- (4- ( (1-hydroxy-2-oxocyclopentyl) methyl) phenyl) propanoic acid. Grades: > 95%. CAS No. 1091621-62-3. Molecular formula: C15H18O4. Mole weight: 262.31. | |
| Loxoprofen Ring-opening Impurity | Loxoprofen Ring-opening Impurity is a degradation product of Loxoprofen, a non-selective nonsteroidal anti-inflammatory drug (NSAID) that has been effective in reducing atherosclerosis in mice by reducing inflammation. Synonyms: 4-(1-Carboxyethyl)-δ-oxo-benzenehexanoic Acid; 2-[4-(2-Oxo-6-carboxy-pentyl)phenyl-propanoic Acid. Grades: > 95%. CAS No. 1091621-61-2. Molecular formula: C15H18O5. Mole weight: 278.3. | |
| L-Penicillamine Hydrochloride | L-Penicillamine Hydrochloride is a metabolite of Penicillin. Penicillin belongs to the β-lactam class of antibiotics, is a very common antibacterial drug. Synonyms: 3-Mercapto-L-valine Hydrochloride; NSC 81988; (R)-2-Amino-3-mercapto-3-methylbutanoic Acid Hydrochloride; Penicillamine DL-form hydrochloride; (+)-penicillamine hydrochloride. Grades: 95%. CAS No. 25526-04-9. Molecular formula: C5H12ClNO2S. Mole weight: 185.67. | |
| L-Phe(1)-Octreotide | L-Phe(1)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: L-phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7); Octreotide Impurity-B; SDZ 206-276; L-Cysteinamide, L-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2?7)-disulfide, [R-(R*,R*)]-; H-L-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr-ol (Disulfide bridge: Cys2-Cys7). CAS No. 109667-07-4. Molecular formula: C49H66N10O10S2. Mole weight: 1019.25. | |
| L-Threoninol(Ac)-8-Octreotide | L-Threoninol(Ac)-8-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: D-phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cystyl-L(Acetyl)-threoninol (Disulfide Bridge between Cys2-Cys7); Octreotide EP Impurity-F; H-D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-Ac-Thr-ol (Disulfide bridge: Cys2-Cys7); L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[1-[(acetyloxy)methyl]-2-hydroxypropyl]-, cyclic (2?7)-disulfide, [R-(R*,R*)]-. CAS No. 133304-81-1. Molecular formula: C51H68N10O11S2. Mole weight: 1061.28. | |
| LTI-291 | LTI-291 is a glucocerebrosidase (Gcase) activator for the treatment of Parkinson's disease (PD). Synonyms: LTI-291; LTI 291; LTI291. 5,7-dimethyl-N-(4-pentoxycyclohexyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide. CAS No. 1919820-28-2. Molecular formula: C20H30N4O2. Mole weight: 358.486. | |
| L-trans-1-Methyl-4-propyl-2-pyrrolidinecarboxamide | L-trans-1-Methyl-4-propyl-2-pyrrolidinecarboxamide is an impurity in the synthesis of Lincomycin, which is a lincosamide antibiotic from the actinomycete Streptomyces lincolnensis. Synonyms: 2-Pyrrolidinecarboxamide, 1-methyl-4-propyl-, L-trans-; (4R)-1-Methyl-4-propyl-L-prolinamide. CAS No. 6838-19-3. Molecular formula: C9H18N2O. Mole weight: 170.25. | |
| Lu AE58054 | Lu AE58054 is a selective and high affinity 5-HT6 receptor antagonist as a promising treatment for cognitive disorders. Uses: 5-ht(6)r antagonist. Synonyms: 2- (6-fluoro-1H-indol-3-yl) -N- (3- (2, 2, 3, 3-tetrafluoropropoxy) benzyl) ethanamine; Lu AE58054; Lu AE-58054; Lu AE 58054; Idalopirdine; Iladopirdine. Grades: ≥98%. CAS No. 467459-31-0. Molecular formula: C20H19F5N2O. Mole weight: 398.37. | |
| Lu AE58054 HCl salt | Lu AE58054 hydrochloride is an in-vitro potency and selectivity, in-vivo binding affinity and effect of the 5-HT(6)R antagonist with a Ki value of 0.83 nM. Synonyms: Lu AE 58054 Hydrochloride. Grades: 0.98. CAS No. 467458-02-2. Molecular formula: C20H20ClF5N2O. Mole weight: 434.835. | |
| Lubiprostone | Lubiprostone is a bicyclic fatty acid metabolite of Prostaglandin E1. It activates ClC-2 and CFTR chloride channels in the gastrointestinal tract, increasing intestinal fluid secretion. It is used in the management of idiopathic chronic constipation, and irritable bowel syndrome with constipation. Synonyms: Prostan-1-oic acid, 16,16-difluoro-11-hydroxy-9,15-dioxo-, (11α)-; (11α)-16,16-Difluoro-11-hydroxy-9,15-dioxoprostan-1-oic acid; RU 0211. Grades: ≥98%. CAS No. 136790-76-6. Molecular formula: C20H32F2O5. Mole weight: 390.47. | |
| Lucinactant | Lucinactant (trade name Surfaxin) is a liquid medication used to treat Infant Respiratory Distress Syndrome in infants. A synthetic human lung surfactant consisting of peptide KL4, dipalmitoylphosphatidylcholine, palmitoyloleoylphosphatidylglycerol, and palmitic acid. Synonyms: ATI 02; KL-surfactant; KL4-surfactant; Surfaxin. Grades: 98%. CAS No. 825600-90-6. Molecular formula: C128H242N26O24. Mole weight: 2529.5. | |
| Lumateperone | Lumateperone, also known as ITI-722 or ITI-007, is a highly potent 5HT2A antagonist for the treatment of sleep maintenance insomnia. Preclinical data has shown that ITI-722 is not sedating and should not exhibit next day hangover effects that are commonly associated with other sleep medications. Synonyms: ITI-722; ITI722; ITI 722; ITI-007; ITI007; ITI 007. Grades: 98%. CAS No. 313368-91-1. Molecular formula: C24H28FN3O. Mole weight: 393.51. | |
| Lumateperone Tosylate | The tosylate salt form of Lumateperone which is an highly effective antagonist of 5-HT2A receptor, could be used against insomnia. IC50: 0.54 nM(Ki). Uses: The tosylate salt form of lumateperone which is an highly effective antagonist of 5-ht2a receptor and could be used against insomnia. Synonyms: Lumateperone (Tosylate);UNII-JIE88N006O; ITI007; JIE88N006O; SCHEMBL1769664. Grades: 98%. CAS No. 1187020-80-9. Molecular formula: C31H36FN3O4S. Mole weight: 565.70. | |
| Lumi-6α-Methylprednisolone 21-Acetate | Lumi-6α-Methylprednisolone 21-Acetate is an impurity of Methylprednisolone, which is a synthetic glucocorticoid used primarily for anti-inflammatory and immunosuppressive effects. Synonyms: (1β, 5β, 6α, 10α, 11β)-9-Fluoro-11, 17-dihydroxy-6, 14-dimethyl-2, 20-dioxo-1, 5-cyclopregn-3-en-21-yl acetate; 1,5-Cyclopregn-3-ene-2,20-dione, 21-(acetyloxy)-9-fluoro-11,17-dihydroxy-6,14-dimethyl-, (1β, 5β, 6α, 10α, 11β)-. Grades: 98%. Molecular formula: C25H33FO6. Mole weight: 448.52. | |
| Lumiflavine | Cas No. 1088-56-8. | |
| Luminespib | Luminespib, also known as AUY-922 (or NVP-AUY922), is a derivative of 4,5-diarylisoxazole and a third-generation heat shock protein 90 (Hsp90) inhibitor with potential antineoplastic activity. Hsp90 inhibitor AUY922 has been shown to bind with high affinity to and inhibit Hsp90, resulting in the proteasomal degradation of oncogenic client proteins. Synonyms: Luminespib; AUY-922; AUY922; AUY 922; NVP-AUY-922; NVP-AUY922; VER-52296; VER52296; VER 52296. Grades: >98%. CAS No. 747412-49-3. Molecular formula: C26H31N3O5. Mole weight: 465.54. | |
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