BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Lamivudine Related Compound (alpha-Troxacitabine) | Troxacitabine is a nucleoside analog with potent anticancer activity. Synonyms: BCH-4556; BCH 4556; BCH4556; (-)-2'-deoxy-3'-oxacytadine; Troxatyl; cis-Dioxolane-C; NSC 668281. Grades: 98%. CAS No. 145918-75-8. Molecular formula: C8H11N3O4. Mole weight: 213.19. |  |
| Lamotrigine | Lamotrigine is an anticonvulsant, inhibiting glutamate release, possibly through inhibition of Na+, K+ and Ca2+ currents. Uses: Anticonvulsants; calcium channel blockers; excitatory amino acid antagonists; voltage-gated sodium channel blockers. Synonyms: lamotrigine; 84057-84-1; 6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diamineLamictalLamictal Cd. Grades: >98%. CAS No. 84057-84-1. Molecular formula: C9H7Cl2N5. Mole weight: 256.09. | |
| Lanifibranor | Lanifibranor is a peroxisome proliferator-activated receptors (PPAR) agonist. Synonyms: Lanifibranor; IVA-337; IVA 337; IVA337; CPD1537; CPD 1537; CPD-1537; 5-Chloro-1-((6-benzothiazolyl)sulfonyl)-1H-indole-2-butanoic acid. CAS No. 927961-18-0. Molecular formula: C19H15ClN2O4S2. Mole weight: 434.909. | |
| Lanreotide | Laromustine is a sulfonyl hydrazine prodrug with antineoplastic activity. Laromustine releases the DNA chloroethylating agent 90CE after entering the blood stream; 90CE chloroethylates alkylates the 06 position of guanine, resulting in DNA crosslinking, strand breaks, chromosomal aberrations, and disruption of DNA synthesis. Intracellular metabolism of this agent also releases methyl isocyanate which inhibits 06-alkyl-guanine transferase, an enzyme involved with DNA repair. Synonyms: Angiopeptin; Autogel; BIM 23014; DC 13-116; Dermopeptin; Ipstyl; L-Autogel; Lanreotide Autogel; Somatulin; Somatulin-Autogel; Somatuline Depot; L-Threoninamide, 3-(2-naphthalenyl)-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-, cyclic (2?7)-disulfide; H-D-2Nal-Cys(1)-Tyr-D-Trp-Lys-Val-Cys(1)-Thr-NH2; 3-(2-naphthyl)-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-L-threoninamide (2->7)-disulfide. Grades: 98%. CAS No. 108736-35-2. Molecular formula: C54H69N11O10S2. Mole weight: 1096.33. | |
| Lanreotide-[d8] TFA salt | Lanreotide-[d8] TFA salt is the labelled salt of Lanreotide, which is a somatostatin analogue with antineoplastic activity. Synonyms: H-D-2Nal-Cys-Tyr-D-Trp-Lys-Val(D8)-Cys-Thr-NH2.TFA (Disulfide bridge between cysteines); D-2-naphthylalanyl-L-cystyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl(D8)-L-cystyl-Threoninamide.TFA (Disulfide bridge between cysteines); Lanreotide D8 TFA salt. Molecular formula: C54H61D8N11O10S2.C2HF3O. Mole weight: 1218.41. | |
| Lanreotide Impurity D | Lanreotide Impurity D is an impurity of Lanreotide, which is a somatostatin analogue with antineoplastic activity. Synonyms: Lanreotide Impurity 1; Lanreotide Acid; DC 23-60; Lanreotide (Deamidized); L-Threonine, 3-(2-naphthalenyl)-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-, cyclic (2?7)-disulfide; 3-(2-naphthyl)-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-L-threonine (2->7)-disulfide; H-D-2Nal-Cys(1)-Tyr-D-Trp-Lys-Val-Cys(1)-Thr-OH; N-{[(4R,7S,10S,13R,16S,19R)-10-(4-Aminobutyl)-16-(4-hydroxybenzyl)-13-(1H-indol-3-ylmethyl)-7-isopropyl-19-{[3-(2-naphthyl)-D-alanyl]amino}-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-L-threonine. CAS No. 150155-56-9. Molecular formula: C54H68N10O11S2. Mole weight: 1097.32. | |
| Lapatinib Ditosylate | Lapatinib is a synthetic, orally-active quinazoline with potential antineoplastic activity. Lapatinib reversibly blocks phosphorylation of the epidermal growth factor receptor (EGFR), ErbB2, and the Erk-1 and-2 and AKT kinases; it also inhibits cyclin D protein levels in human tumor cell lines and xenografts. EGFR and ErbB2 have been implicated in the growth of various tumor types. Uses: Antineoplastic agents. Synonyms: GW-572016; GW 572016; GW572016. Grades: >98%. CAS No. 388082-77-7. Molecular formula: C29H26ClFN4O4S.2C7H8O3S. Mole weight: 925.46. | |
| Lapatinib Hydroxylamine | a complex used in human metabolism of lapatinib which is a dual kinase inhibitor. Synonyms: N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[[hydroxy[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-4-quinazolinamine. Grades: > 95%. CAS No. 1360431-86-2. Molecular formula: C29H26ClFN4O5S. Mole weight: 597.07. | |
| Larazotide acetate | Larazotide acetate is a tight junction regulator and reverses leaky junctions to their normally closed state. Synonyms: H-Gly-Gly-Val-Leu-Val-Gln-Pro-Gly-OH.CH3CO2H. Grades: 98%. CAS No. 881851-50-9. Molecular formula: C34H59N9O12. Mole weight: 785.9. | |
| L-Arg(1)-Icatibant | L-Arg(1)-Icatibant is an impurity of Icatibant, which is a selective and specific antagonist of bradykinin B2 receptor. Synonyms: L-arginyl-L-arginyl-L-prolyl-L-hydroxyprolyl-glycyl-L-thienylalanyl-L-seryl-D-1,2,3,4-tetrahydroisoquinolyl-L-octahydroindole-L-arginine; Arg-Arg-Pro-Hyp-Gly-Thi-Ser-D-Tic-Oic-Arg-OH; L-Arginine, L-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-(3R)-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-(2S,3aS,7aS)-octahydro-1H-indole-2-carbonyl-. CAS No. 193618-59-6. Molecular formula: C59H89N19O13S. Mole weight: 1304.54. | |
| Laropiprant | a drug used in combination with niacin to reduce blood cholesterol (LDL and VLDL) that is no longer sold. Uses: A potent, selective dp1 receptor antagonist. Synonyms: (3R)-4-[(4-chlorophenyl)methyl]-7-fluoro-1,2,3,4-tetrahydro-5-(methylsulfonyl)-cyclopent[b]indole-3-acetic acid. Grades: > 95%. CAS No. 571170-77-9. Molecular formula: C21H19ClFNO4S. Mole weight: 435.91. | |
| Lasofoxifene | Lasofoxifene (INN) (proposed tradename Fablyn) is a non-steroidal selective estrogen receptor modulator (SERM) which is under development by Pfizer for the prevention and treatment of osteoporosis and for the treatment of vaginal atrophy, and the result of an exclusive research collaboration with Ligand Pharmaceuticals (LGND). In September 2005, Pfizer received a non-approvable letter from the U.S. Food and Drug Administration regarding lasofoxifene ( Oporia), a selective estrogen receptor modulator for the prevention of osteoporosis. Lasofoxifene was approved in the EU under the Fablyn by the EMEA in March 2009. Lasofoxifene is a desmethyl dihydro analog of nafoxidine. Synonyms: CP 336156; CP336156; CP-336156; CP 336,156; CP336,156; CP-33,6156; Fably; Oporia. Grades: >98%. CAS No. 180916-16-9. Molecular formula: C28H31NO2. Mole weight: 413.561. | |
| Lasofoxifene tartrate | Lasofoxifene tartrate is the tartrate salt form of Lasofoxifene. Lasofoxifene is a third-generation selective estrogen receptor modulators (SERMs). Synonyms: CP-336156; CP 336156; CP336156; (2R,3R)-2,3-dihydroxybutanedioic acid;(5R,6S)-6-phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalen-2-ol; LASOFOXIFENE HCL;(5R,6S)-5,6,7,8-Tetrahydro-6-phenyl-5-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-2-naphthalenol (2S,3S)-2,3-dihydrox. Grades: 95%. CAS No. 190791-29-8. Molecular formula: C28H31NO2.C4H6O6. Mole weight: 563.65. | |
| Latamoxef | Latamoxef is an oxacephem antibiotic usually grouped with the cephalosporins. Uses: Latamoxef is used for the treatment of susceptible bacterial infections. Synonyms: 5-oxa-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylicacid,7-((carboxy(4-hydroxyphen; Moxalactam, Lamoxactam, Festamoxin. Grades: > 95%. CAS No. 64952-97-2. Molecular formula: C20H20N6O9S. Mole weight: 520.48. | |
| Latanoprostene Bunod | Latanoproste bunod is a nitric oxide-donating prostaglandin F2α (FP) receptor agonist. Under the trade name Vyzulta, it has been approved for the treatment of intraocular pressure in patients with open-angle glaucoma or ocular hypertension in 2017. Synonyms: BOL-303259-X; NCX 116; PF-3187207. Grades: ≥95%. CAS No. 860005-21-6. Molecular formula: C27H41NO8. Mole weight: 507.62. | |
| Lavendustin A | Lavendustin A is an epidermal growth factor receptor inhibitor tyrosine kinase with IC50 value of 11 nM. Synonyms: Lavendustin A; RG 14355; RG-14355; RG14355; 5-[[(2,5-Dihydroxyphenyl)methyl][(2-hydroxyphenyl)methyl]amino]-2-hydroxybenzoic acid. Grades: ≥98% by HPLC. CAS No. 125697-92-9. Molecular formula: C21H19NO6. Mole weight: 381.38. | |
| L-Biopterin | L-Biopterin is an oxidation product from the melanogenesis regulating cofactor (6R)5,6,7,8 tetrahydrobiopterin (6-BH4). It is an important cofactor in the production of many essential neurotransmitters, such as dopamine, seratonin and epinephrine, and plays an important role in the production of nitric oxide in the body. It has been shown to be cytotoxic to melanocytes in vitro, and may be a useful noninvasive biomarker. Synonyms: L-Biopterin; NSC 339699; NSC-339699; NSC339699; AR 1D8544; AR-1D8544; AR1D8544; LS126316; LS-126316; LS 126316; 2-Amino-6-[(1R,2S)-1,2-dihydroxypropyl]-4(1H)-pteridinone; (-)-Biopterin; 6-Biopterin; Biopterin; L-erythro-Biopterin; NSC 339699; Pterin H B2; (1'R,2'S)-Biopterin; L-erythro-6-(1,2-Dihydroxypropyl)pterin. Grades: >95%. CAS No. 22150-76-1. Molecular formula: C9H11N5O3. Mole weight: 273.22. | |
| L-Buthionine Sulfone | L-Buthionine Sulfone is a potential inhibitor of human γ-glutamylcysteine synthetase used to sensitize tumors to cytotoxic drugs. Synonyms: (S)-2-Amino-4-(butylsulfonyl)butanoic Acid; (2S)-2-Amino-4-(butylsulfonyl)butanoic Acid. CAS No. 134859-31-7. Molecular formula: C8H17NO4S. Mole weight: 223.29. | |
| LCL-161 | LCL161 is an orally bioavailable second mitochondrial-derived activator of caspases (SMAC) mimetic and inhibitor of IAP (Inhibitor of Apoptosis Protein) family of proteins, with potential antineoplastic activity. SMAC mimetic LCL161 binds to IAPs, such as X chromosome-linked IAP (XIAP) and cellular IAPs 1 and 2. Since IAPs shield cancer cells from the apoptosis process, this agent may restore and promote the induction of apoptosis through apoptotic signaling pathways in cancer cells. IAPs are overexpressed by many cancer cell types and suppress apoptosis by binding and inhibiting active caspases-3, -7 and -9, which play essential roles in apoptosis (programmed cell death), necrosis and inflammation. Synonyms: LCL161; LCL 161; LCL-161. CAS No. 1005342-46-0. Molecular formula: C26H33FN4O3S. Mole weight: 500.633. | |
| LCS3 | LCS3 is a reversible inhibitor of glutathione disulfide reductase (GSR) and thioredoxin reductase 1 (TXNRD1) with IC50 of 3.3 μM and 3.8 μM, respectively. CAS No. 109844-92-0. Molecular formula: C11H7ClN2O4. Mole weight: 266.64. | |
| L-Cysteine | L-Cysteine is a non-essential amino acid that can be synthesized by the human body under normal physiological conditions if a sufficient quantity of methionine is available. L-Cysteine is commonly used as a precursor in the food and pharmaceutical industries. L-Cysteine is used as a processing aid for baking, as an additive in cigarettes, as well as in the preparation of meat flavours. Synonyms: Cysteine, L-; (R)-2-Amino-3-mercaptopropanoic acid; (R)-2-Amino-3-sulfanylpropanoic acid; (R)-Cysteine; L-(+)-Cysteine; L-Alanine, 3-mercapto-; L-Cys; Cystein; Cysteine; E 920; Half-cystine; NSC 8746; Propanoic acid, 2-amino-3-mercapto-, (R)-; Thioserine; β-Mercaptoalanine. Grades: ≥95%. CAS No. 52-90-4. Molecular formula: C3H7NO2S. Mole weight: 121.16. | |
| L-Cysteine S-Sulfate | L-Cysteine S-Sulfate is one of Cysteine impurities. It has potential anticancer activity against tumor cell growth. Synonyms: S-Sulfo-L-cysteine. CAS No. 1637-71-4. Molecular formula: C3H7NO5S2. Mole weight: 201.22. | |
| LDC1267 | LDC1267 is a highly selective TAM kinase inhibitor with IC50 of <5 nM, 8 nM, and 29 nM for Mer, Tyro3, and Axl, respectively. Displays lower activity against Met, Aurora B, Lck, Src, and CDK8. Synonyms: LDC1267; LDC 1267; LDC-1267. Grades:>98%. CAS No. 1361030-48-9. Molecular formula: C30H26F2N4O5. Mole weight: 560.55. | |
| LDN-193189 HCl | LDN193189 HCl is the hydrochloride salt of LDN193189, which is a selective BMP signaling inhibitor, and inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 of 5 nM and 30 nM, respectively. Synonyms: LDN-193189 monohydrochloride; LDN 193189 monohydrochloride; LDN193189 monohydrochloride. Grades: >98%. CAS No. 1062368-62-0. Molecular formula: C25H22N6.HCl. Mole weight: 442.94. | |
| LE 135 | LE 135 is a retinoic acid antagonist which shows moderate selectivity for RARβ over RAR&alpha. It can inhibit human HL-60 leukemia cell differentiation induced by Am80 with IC50 value of 150 nM. Synonyms: LE135; LE-135; 4-(7,8,9,10-Tetrahydro-5,7,7,10,10-pentamethyl-5H-benzo[e]naphtho[2,3-b][1,4]diazepin-13-yl)benzoic acid; Benzoic acid, 4-(7,8,9,10-tetrahydro-5,7,7,10,10-pentamethyl-5H-benzo[e]naphtho[2,3-b][1,4]diazepin-13-yl)-. Grades: ≥97% by HPLC. CAS No. 155877-83-1. Molecular formula: C29H30N2O2. Mole weight: 438.56. | |
| Ledipasvir acetone | Ledipasvir is an inhibitor of hepatitis C virus NS5A. Synonyms: GS 5885 acetone; GS5885 acetone; GS-5885 acetone; methyl ((S)-1-((S)-6-(5-(9,9-difluoro-7-(2-((1R,3S,4S)-2-((methoxycarbonyl)-L-valyl)-2-azabicyclo[2.2.1]heptan-3-yl)-1H-benzo[d]imidazol-6-yl)-9H-fluoren-2-yl)-1H-imidazol-2-yl)-5-azaspiro[2.4]heptan-5-yl)-3-methyl-1-oxobutan-2-yl)carbamate compound with propan-2-one (1:1). Grades: >98%. CAS No. 1441674-54-9. Molecular formula: C52H60F2N8O7. Mole weight: 947.08. | |
| LEE011 succinate | LEE011 is an orally bioavailable and highly specific CDK4/6 (cyclin-dependent kinase 4/6) inhibitor. LEE011 in combination with LGX818 (a V600E BRAF specific inhibitor) or BYL719 (a PIK3CA specific inhibitor) leads to robust anti-tumor activity in melanoma and breast cancer tumor models. Synonyms: Ribociclib succinate; LEE 011 succinate; LEE-011 succinate. Grades: >98%. CAS No. 1374639-75-4. Molecular formula: C27H36N8O5. Mole weight: 552.63. | |
| Lenvatinib | Lenvatinib (E7080) is a multi-target inhibitor, mostly for VEGFR2(KDR)/VEGFR3(Flt-4) with IC50 of 4 nM/5.2 nM, less potent against VEGFR1/Flt-1, ~10-fold more selective for VEGFR2/3 against FGFR1, PDGFRα/&beta. Synonyms: 4-[3-chloro-4-[[ (cyclopropylamino) carbonyl]amino]phenoxy]-7-methoxy-6-quinolinecarboxamide; E-7080; E 7080; E7080; ER-203492-00. Grades: >98%. CAS No. 417716-92-8. Molecular formula: C21H19ClN4O4. Mole weight: 426.85. | |
| Lenvatinib N-Oxide | One of the impurities of Lenvatinib. Lenvatinib is a multi-target inhibitor, mostly for VEGFR2(KDR)/VEGFR3(Flt-4) with IC50 of 4 nM/5.2 nM, less potent against VEGFR1/Flt-1, ~10-fold more selective for VEGFR2/3 against FGFR1, PDGFRα/&beta. Synonyms: 6-Carbamoyl-4-(3-chloro-4-(3-cyclopropylureido)phenoxy)-7-methoxyquinoline 1-Oxide; 4-[3-Chloro-4-[[ (cyclopropylamino) carbonyl]amino]phenoxy]-7-methoxy-6-quinolinecarboxamide 1-Oxide; Lenvatinib Impurity 10. CAS No. 1788901-86-9. Molecular formula: C21H19ClN4O5. Mole weight: 442.85. | |
| Lepirudin | Lepirudin is an anticoagulant that acts as a direct thrombin inhibitor. Lepirudin binds to both free and clot-bound thrombin. Lepirudin is approved for the treatment of heparin-induced thrombocytopenia (HIT). Uses: The treatment of heparin-induced thrombocytopenia (hit). Synonyms: (Leu1,Thr2)-Hirudin (desulfated); Lepirudin; Refludan; Refludin; Hbw 023; Hbw-023; Hbw023. CAS No. 138068-37-8. Molecular formula: C287H440N80O111S6. Mole weight: 6979.41. | |
| Leptin (22-56), human | Leptin (22-56) (human) is the fragment of leptin, a hormone produced by the fat cells in human body. Synonyms: H-Val-Pro-Ile-Gln-Lys-Val-Gln-Asp-Asp-Thr-Lys-Thr-Leu-Ile-Lys-Thr-Ile-Val-Thr-Arg-Ile-Asn-Asp-Ile-Ser-His-Thr-Gln-Ser-Val-Ser-Ser-Lys-Gln-Lys-OH; L-valyl-L-prolyl-L-isoleucyl-L-glutaminyl-L-lysyl-L-valyl-L-glutaminyl-L-alpha-aspartyl-L-alpha-aspartyl-L-threonyl-L-lysyl-L-threonyl-L-leucyl-L-isoleucyl-L-lysyl-L-threonyl-L-isoleucyl-L-valyl-L-threonyl-L-arginyl-L-isoleucyl-L-asparagyl-L-alpha-aspartyl-L-isoleucyl-L-seryl-L-histidyl-L-threonyl-L-glutaminyl-L-seryl-L-valyl-L-seryl-L-seryl-L-lysyl-L-glutaminyl-L-lysine. Grades: >95%. CAS No. 183598-56-3. Molecular formula: C171H298N50O56. Mole weight: 3950.49. | |
| Leptin (human) | Leptin (human) is a peptide hormone secreted from white adipocytes and implicated in the regulation of food intake and energy balance. Synonyms: 1: PN: WO0038651 SEQID: 1 unclaimed protein; 22-167-Protein (human gene obese 167-amino acid isoform precursor); Anti-obesity protein (human); Leptin (human clone 3 gene Ob); Leptin (human gene ob protein 146-amino acid fragment); Leptin (synthetic human mutant 15B); Protein (human gene ob active isoform). Grades: ≥95% by HPLC. CAS No. 177404-21-6. | |
| Lercanidipine Hydrochloride | A dihydropyridine calcium channel blocker. Antihypertensive. Uses: The hydrochloride salt form of lercanidipine could be used as an antihypertensive agent through influencing the l-type ca2+ channel at some extent. Synonyms: 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 2-[(3,3-Diphenylpropyl)methylamino]-1,1-dimethylethyl Methyl Ester Hydrochloride. Grades: > 95%. CAS No. 132866-11-6. Molecular formula: C36H41N3O6·HCl. Mole weight: 648.19. | |
| Lesinurad | Lesinurad(RDEA594), once-daily inhibitor of URAT1, is a transporter in the kidney that regulates uric acid excretion from the body. Synonyms: 2-[[5-Bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]thio]acetic acid; RDEA 594; Zurampic; [[5-bromo-4-(4-cyclopropyl-1-naphthalenyl)-4H-1,2,4-triazol-3-yl]thio]-acetic Acid; Lesinida. Grades: >98%. CAS No. 878672-00-5. Molecular formula: C17H14BrN3O2S. Mole weight: 404.28. | |
| Lesinurad Impurity 16 | An intermediate of Lesinurad, a urate transporter inhibitor used for the treatment of high blood uric acid levels associated with gout. Synonyms: Methyl 2-(5-broMo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-ylthio)acetate. Grades: > 95%. CAS No. 878671-99-9. Molecular formula: C18H16BrN3O2S. Mole weight: 418.32. | |
| [Leu15]-Gastrin I (human) | A derivative of Gastrin I (human), an endogenous peptide produced by stomach and it acts as a selective CCK2 receptor agonist. Synonyms: H-DL-Pyr-Gly-DL-Pro-DL-Trp-DL-Leu-DL-Glu-DL-Glu-DL-Glu-DL-Glu-DL-Glu-DL-Ala-DL-Tyr-Gly-DL-Trp-DL-Leu-DL-Asp-DL-Phe-NH2. Grades: ≥98%. CAS No. 39024-57-2. Molecular formula: C98H126N20O31. Mole weight: 2080.16. | |
| Leu 3-Oxytocin | Leu 3-Oxytocin is an impurity of Oxytocin, which is a mammalian neurohypophysial hormone used as a vasodilator agent. Synonyms: L-cystyl-L-tyrosyl-L-leucyl-L-glutaminyl-L-asparginyl-L-cystyl-L-leucyl-L-prolyl-L-glycinamide (disulfide bridge between cysteines); H-Cys-Tyr-Leu-Gln-Asn-Cys-Pro-Leu-Gly-NH2 (Disulfide bridge: Cys1-Cys6); Oxytocin, 3-L-leucine-; 1,2-Dithia-5,8,11,14,17-pentaazacycloeicosane-10-propionamide, 19-amino-7-(carbamoylmethyl)-4-[2-[[1-[(carbamoylmethyl)carbamoyl]-3-methylbutyl]carbamoyl]-1-pyrrolidinylcarbonyl]-16-p-hydroxybenzyl-13-isobutyl-6,9,12,15,18-pentaoxo-; Oxytocin, 3-leucine; 3-Leucine oxytocin; [Leu3]-Oxytocin. Grades: ≥95%. CAS No. 4294-11-5. Molecular formula: C43H66N12O12S2. Mole weight: 1007.19. | |
| Leu(7)-AVP | Leu(7)-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: Leu(7)-Vasopressin; H-Cys-Tyr-Phe-Gln-Asn-Cys-Leu-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); Vasopressin, 7-L-leucine-8-L-arginine-; L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-leucyl-L-arginyl-glycinamide (1->6)-disulfide. CAS No. 58500-94-0. Molecular formula: C46H65N15O12S2. Mole weight: 1100.28. | |
| Leucovorin Calcium | leucovorin calcium is an active metabolite of folic acid (also called folinic acid and citrovorum factor), which does not require metabolism by dihydrofolate reductase, the molecular target of folate antagonist-type chemotherapeutic drugs. Leucovorin calcium counteracts the toxic effects of these medications, 'rescuing' the patient while permitting the antitumor activity of the folate antagonist. This agent also potentiates the effects of fluorouracil and its derivatives by stabilizing the binding of the drug's metabolite to its target enzyme, thus prolonging drug activity. Synonyms: IST5-002; IST5 002; IST5002; Benzyl-AMP; N6-Benzyladenosine-5'-phosphate; Folinic acid calcium salt; Calcium Folinate. Grades: >98%. CAS No. 1492-18-8. Molecular formula: C20H21N7O7.Ca. Mole weight: 513.52. | |
| Leuprolide (5-9) | Leuprolide (5-9) is an impurity of Leuprolide, which is a synthetic nonapeptide analog of gonadotropin-releasing hormone used as an antineoplastic agent, a gonadotropin-releasing hormone agonist, and an anti-estrogen. Synonyms: L-tyrosyl-D-leucyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide; Leuprolide-Metabolite (pentapeptide); H-Tyr-D-Leu-Leu-Arg-Pro-NHEt; 5-9 Leuprolide; L-Prolinamide, L-tyrosyl-D-leucyl-L-leucyl-L-arginyl-N-ethyl-; L-tyrosyl-D-leucyl-L-leucyl-L-arginyl-L-proline ethylamide. Grades: ≥95%. CAS No. 129244-90-2. Molecular formula: C34H57N9O6. Mole weight: 687.87. | |
| Leuprolide-[d10] | Leuprolide-[d10] is the labelled analogue of Leuprolide, which is a synthetic nonapeptide analog of gonadotropin-releasing hormone used as an antineoplastic agent, a gonadotropin-releasing hormone agonist, and an anti-estrogen. Synonyms: Leuprolide D10 (labelled); Pyr-His-Trp-Ser-Tyr-D-Leu-Leu(D10)-Arg-Pro-NHEt; 5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl(D10)-L-arginyl-N-ethyl-L-prolinamide. Molecular formula: C59H74D10N16O12. Mole weight: 1219.48. | |
| Leuprolide Impurity-12 | Leuprolide Impurity-12 is an impurity of Leuprolide, which is a synthetic nonapeptide analog of gonadotropin-releasing hormone used as an antineoplastic agent, a gonadotropin-releasing hormone agonist, and an anti-estrogen. Synonyms: 5-Oxo-L-prolyl-L-Histidyl-L-Tryptophan; Pyr-His-Trp-OH; Leuprolide (1-3); Leuprolide (m3); L-pyroglutamyl-L-histidyl-L-tryptophan; L-Tryptophan, 5-oxo-L-prolyl-L-histidyl-; L-Tryptophan, N-[N-(5-oxo-L-prolyl)-L-histidyl]-; (Pyro)-L-glutamic acid-L-histidine-L-tryptophan-OH; L-Pyroglu-L-His-L-Trp; LH-RH (1-3). Grades: ≥95%. CAS No. 35925-21-4. Molecular formula: C22H24N6O5. Mole weight: 452.47. | |
| Leuprolide impurity (1-8) | Leuprolide impurity (1-8) is an impurity of Leuprolide, which is a synthetic nonapeptide analog of gonadotropin-releasing hormone used as an antineoplastic agent, a gonadotropin-releasing hormone agonist, and an anti-estrogen. Synonyms: Pyr-His-Trp-Ser-Tyr-D-Leu-Leu-Arg; 5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-Seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginine; LHRH (1-8); 1-8-Luteinizing hormone-releasing factor (swine), 6-D-leucine-; Luteinizing hormone-releasing factor (pig), 6-D-leucine-9-de-L-proline-10-deglycinamide-; L-pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginine. Grades: ≥95% by HPLC. CAS No. 112642-14-5. Molecular formula: C52H72N14O12. Mole weight: 1085.23. | |
| Leuprolide Impurity-6 | Leuprolide Impurity-6 is an impurity of Leuprolide, which is a synthetic nonapeptide analog of gonadotropin-releasing hormone used as an antineoplastic agent, a gonadotropin-releasing hormone agonist, and an anti-estrogen. Synonyms: L-Histidyl-L-Tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide; His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt; L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl-L-proline ethylamide. Grades: ≥95%. CAS No. 1642799-35-6. Molecular formula: C54H79N15O10. Mole weight: 1098.32. | |
| Levamisole Impurity D (HCl salt form) | The hydrochloride of Levamisole Impurity D. Levamisole is a medication used for the treatment of parasitic worm infections. It was also indicated to be effective for colon cancer therapy in combination with fluorouracil. Synonyms: 6-phenyl-2,3-dihydroimidazo[2,1-b]thiazole hydrochloride; AC1MD4BJ; CTK8I7338; MolPort-000-653-456. Grades: 95%. CAS No. 4335-29-9. Molecular formula: C11H11ClN2S. Mole weight: 238.733. | |
| Levobetaxolol HCl | Levobetaxolol exhibits a higher affinity at cloned human β1 and β2 receptors with Ki value of 0.76 nM and 32.6 nM, respectively. Synonyms: AL 1577A; AL-1577A; AL1577A. Grades: >98%. CAS No. 116209-55-3. Molecular formula: C18H29NO3.HCl. Mole weight: 343.89. | |
| Levobupivacaine free base | Levobupivacaine is a local anaesthetic drug belonging to the amino amide group. It is the S-enantiomer of bupivacaine. Levobupivacaine hydrochloride is commonly marketed by Abbott under the trade name Chirocaine. It acts via reversibly binding voltage-gated sodium channels to modulate ionic flux and block the initiation and transmission of nerve impulses. Uses: Local anaesthetic drug. Synonyms: (S)-1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide; Levobupivacaine free base; (S)-1-Butyl-2',6'-pipecoloxylidide; L(-)-Bupivacaine. Grades: 98%. CAS No. 27262-47-1. Molecular formula: C18H28N2O. Mole weight: 288.44. | |
| Levodropropizine (S-Dropropizine) | Levodropropizine possess anti-allergic and inhibits histamine receptor, reduces cough by interfering with stimulus activation of peripheral endings of sensory nerves and by modulation of neuropeptides involved in the cough reflex. Synonyms: Levodropropizine; DF 526; DF-526; DF526; Levotuss. Grades: >98%. CAS No. 99291-25-5. Molecular formula: C13H20N2O2. Mole weight: 236.31. | |
| Levo-(-)-Flumequine | Grades: > 95%. Molecular formula: C14H12FNO3. Mole weight: 261.26. | |
| Levomefolate | A natural, active form of folic acid used at the cellular level for DNA reproduction, the cysteine cycle and the regulation of homocysteine among other functions. It is a coenzymated form of folic acid and a more bioavailable alternative in dietary supplements. It has been proposed for treatment of cardiovascular disease. Synonyms: 5-MTHF. Grades: >98%. CAS No. 31690-09-2. Molecular formula: C20H25N7O6. Mole weight: 459.46. | |
| Levomilnacipran Hydrochloride | Levomilnacipran (brand name Fetzima) is an antidepressant approved for the treatment of major depressive disorder in the United States. It was developed by Forest Laboratories and Pierre Fabre Group, and was approved by the Food and Drug Administration in July 2013. Levomilnacipran is the levo-enantiomer of milnacipran, and has similar effects and pharmacology, acting as a serotonin-norepinephrine reuptake inhibitor (SNRI). Uses: Antidepressive agents. Synonyms: (1S,2R)-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide Hydrochloride; cis-(+)-Milnacipran Hydrochloride; (1S,2R)-Milnacipran Hydrochloride; (1S-cis)-Milnacipran Hydrochloride. Grades: 98%. CAS No. 175131-60-9. Molecular formula: C15H23ClN2O. Mole weight: 282.81. | |
| Levosimendan | Levosimendan is a calcium sensitizer acting through calcium-dependent binding to cardiac troponin C (cTnC). Uses: Vasodilator agents. Synonyms: [ [4- [ (4R) -1, 4, 5, 6-Terahydro-4-methyl-6-oxo-3-pyridazinyl] phenyl] hydrazono] propanedinitrile. Grades: >98%. CAS No. 141505-33-1. Molecular formula: C14H12N6O. Mole weight: 280.28. | |
| Levothyroxine sodium | Levothyroxine sodium is the hormone derived from thyroid gland. Synonyms: Thyroid powder; L-Thyroxine sodium; Euthyrox; Unithroid; Novothyrox. CAS No. 50809-32-0. Molecular formula: C15H10I4NNaO4. Mole weight: 798.856. | |
| L-Homocysteine Thiolactone Hydrochloride | L-Homocysteine Thiolactone Hydrochloride is used to prepare substituted homocysteine analogs as inhibitors of peptidylglycine α-amidating monooxygenase. It is also used to synthesize (mercaptoacyl)alanylprolines as metalloprotease inhibitors. Synonyms: (3S)-3-Aminodihydro-2(3H)-thiophenone Hydrochloride; (S)-3-Aminodihydro-2(3H)-thiophenone Hydrochloride; L-3-Aminodihydro-2(3H)-thiophenone Hydrochloride. Grades: > 95%. CAS No. 31828-68-9. Molecular formula: C4H8ClNOS. Mole weight: 153.63. | |
| Liberine | Liberine is one of Caffeine metabolites. Caffeine is a CNS stimulant. Alkaloid, purified from plants of Coffea genus, Rubiaceae. Synonyms: O2,1,9-Trimethyluric Acid; 7,9-Dihydro-2-methoxy-1,9-dimethyl-1H-purine-6,8-dione; 2-Methoxy-1,9-dimethyl-1H-purine-6,8(7H,9H)-dione; O(2),1,9-trimethylurate; 2-methoxy-1,9-dimethyl-6,7,8,9-tetrahydro-1H-purine-6,8-dione. Grades: 98%. CAS No. 56119-16-5. Molecular formula: C8H10N4O3. Mole weight: 210.19. | |
| Lifitegrast | Cas No. 1025967-78-5. | |
| LIK066 | LIK066 is a potent sodium-glucose transporter 1 and sodium-glucose transporter 2 inhibitor originated by Novartis Pharmaceuticals Corporation IC50 with value of 22.0 nM against human SGLT1 and 0.5 nM against human SGLT2. In Apr 2016, Novartis completed a phase II trial for Type 2 diabetes mellitus in USA. Uses: Type 2 diabetes mellitus. Synonyms: LIK-066; LIK 066; licogliflozin. Grades: 98%. CAS No. 1291094-73-9. Molecular formula: C51H65NO16. Mole weight: 948.07. | |
| Linaclotide | Linaclotide is a peptide agonist of guanylate cyclase 2C that is undergoing clinical trials for use in treating abdominal pain in patients with irritable bowel syndrome (IBS) accompanied by constipation. The drug also has promising outlooks for the treatment of gastroparesis, ulcerative colitis, chronic intestinal pseudo-obstruction (CIPO), and inertia coli as well. Synonyms: Constella; Linzess; L-Tyrosine, L-cysteinyl-L-cysteinyl-L-α-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparaginyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteinyl-, cyclic (1?6),(2?10),(5?13)-tris(disulfide); L-cysteinyl-L-cysteinyl-L-α-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparagyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonyl-glycyl-L-cysteinyl-L-tyrosine (1->6),(2->10),(5->13)-tris(disulfide); H-Cys-Cys-Glu-Tyr-Cys-Cys-Asn-Pro-Ala-Cys-Thr-Gly-Cys-Tyr-OH (Disulfide bridge: Cys1-Cys6, Cys2-Cys10, Cys5-Cys13). Grades: ≥95%. CAS No. 851199-59-2. Molecular formula: C59H79N15O21S6. Mole weight: 1526.74. | |
| Linagliptin Des-Piperidine amine | An impurity of Linagliptin, a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes. Synonyms: Linagliptin J; 1H-Purine-2,6-dione, 7-(2-butyn-1-yl)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-. Grades: ≥95%. CAS No. 1911621-52-7. Molecular formula: C20H18N6O2. Mole weight: 374.40. | |
| Linagliptin Impurity 10 (S-Isomer) | a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes. Synonyms: (S)-Linagliptin; 8-[(3S)-3-Amino-1-piperidinyl]-7-(2-butyn-1-yl)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-1H-purine-2,6-dione. Grades: > 95%. CAS No. 668270-11-9. Molecular formula: C25H28N8O2. Mole weight: 472.55. | |
| Linagliptin Impurity B | An impurity of Linagliptin, a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes. Synonyms: 8-Bromo-3-methyl-1,7-bis((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione; 1H-Purine-2,6-dione, 8-bromo-3,7-dihydro-3-methyl-1,7-bis[(4-methyl-2-quinazolinyl)methyl]-; 8-Bromo-3,7-dihydro-3-methyl-1,7-bis[(4-methyl-2-quinazolinyl)methyl]-1H-purine-2,6-dione. Grades: ≥95%. CAS No. 2138392-83-1. Molecular formula: C26H21BrN8O2. Mole weight: 557.41. | |
| Linagliptin Impurity E | An impurity of Linagliptin, a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes. Synonyms: Des-(R)-piperidin-3-amine 8-(R)-(Piperidin-3-ylamino) Linagliptin; (R)-7-(but-2-ynyl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-8-(piperidin-3-ylamino)-1H-purine-2,6(3H,7H)-dione. CAS No. 1446263-38-2. Molecular formula: C25H28N8O2. Mole weight: 472.5. | |
| Linagliptin Impurity KH | An impurity of Linagliptin, a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes. Grades: ≥95%. Molecular formula: C25H29N7O4. Mole weight: 491.55. | |
| Linagliptin impurity KH-3 | An impurity of Linagliptin, a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes. Synonyms: tert-butyl (R)-(1-(1-(2-((2-acetylphenyl)amino)-2-oxoethyl)-7-(but-2-yn-1-yl)-3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)carbamate; (R)-tert-Butyl (1-(1-(2-((2-acetylphenyl)amino)-2-oxoethyl)-7-(but-2-yn-1-yl)-3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)carbamate. Grades: ≥95%. CAS No. 2279114-27-9. Molecular formula: C30H37N7O6. Mole weight: 591.66. | |
| Linagliptin Impurity QJ | An impurity of Linagliptin, a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes. Grades: ≥95%. Molecular formula: C25H27N7O3. Mole weight: 473.54. | |
| Linagliptin Impurity SIM | An impurity of Linagliptin, a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes. Grades: ≥95%. Molecular formula: C26H21BrN8O2. Mole weight: 557.41. | |
| Linagliptin Impurity SQBOC | An impurity of Linagliptin, a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes. Grades: ≥95%. Molecular formula: C24H32N6O4. Mole weight: 468.56. | |
| Linagliptin Impurity XDBoc | An impurity of Linagliptin, a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes. Grades: ≥95%. Molecular formula: C30H37BrN8O4. Mole weight: 653.58. | |
| Linagliptin Impurity YYJ | An impurity of Linagliptin, a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes. Synonyms: 7-(But-2-yn-1-yl)-8-ethoxy-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione (Linagliptin Impurity); Linagliptin Impurity YYJ. Grades: ≥95%. CAS No. 1803079-48-2. Molecular formula: C22H22N6O3. Mole weight: 418.46. | |
| Linagliptin Methyldimer | An impurity of Linagliptin, a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes. Synonyms: 8-[(3R)-3-Amino-1-piperidinyl]-1-[[4-[[2-[[8-[(3R)-3-amino-1-piperidinyl]-7-(2-butyn-1-yl)-2,3,6,7-tetrahydro-3-methyl-2,6-dioxo-1H-purin-1-yl]methyl]-1,4-dihydro-4-methyl-4-quinazolinyl]methyl]-2-quinazolinyl]methyl]-7-(2-butyn-1-yl)-3,7-dihydro-3-methyl-1H-purine-2,6-dione; 8-((R)-3-Aminopiperidin-1-yl)-1-((4-((2-((8-((R)-3-aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-1-yl)methyl)-4-methyl-1,4-dihydroquinazolin-4-yl)methyl)quinazolin-2-yl)methyl)-7-(but-2-yn-1-yl)-3-methyl-1H-purine-2,6(3H,7H)-dione; Linagliptin Dimer Impurity. Grades: > 95%. CAS No. 1418133-47-7. Molecular formula: C50H56N16O4. Mole weight: 945.08. | |
Our database is helping our users find suppliers everyday.
