BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Givinostat | Givinostat (INN) or gavinostat, aslo known as ITF2357, is a histone deacetylase inhibitor with potential anti-inflammatory, anti-angiogenic, and antineoplastic activities. It is a hydroxamate used in the form of its hydrochloride. Givinostat is in numerous phase II clinical trials (including for relapsed leukemias and myelomas), and has been granted orphan drug designation in the European Union for the treatment of systemic juvenile idiopathic arthritis and polycythaemia vera. ITF2357 was discovered at Italfarmaco of Milan, Italy. It was patented in 1997 and first described in the scientific literature in 2005. Synonyms: Givinostat; gavinostat; ITF-2357; ITF 2357; ITF2357. CAS No. 497833-27-9. Molecular formula: C24H27N3O4. Mole weight: 421.497. |  |
| Givinostat hydrochloride | Givinostat hydrochloride is the hydrochloride salt form of Givinostat. Givinostat, also called as GVS or ITF2357, a potent HDAC inhibitor for Maize HD2 (IC50= 10 nM), HD1-B (IC50= 7.5 nM nM) and HD1-A (IC50= 16 nM), has antiproliferative and proapoptotic. Uses: Histone deacetylase inhibitors. Synonyms: (6-((diethylamino)methyl)naphthalen-2-yl)methyl (4-(hydroxycarbamoyl)phenyl)carbamate hydrochloride; ITF2357; ITF-2357; ITF 2357; ITF2357 HCl; ITF2357 hydrochloride; Givinostat HCl gavinostat. CAS No. 199657-29-9. Molecular formula: C24H28ClN3O4. Mole weight: 457.95. | |
| Givinostat hydrochloride monohydrate | Givinostat, also known as ITF2357, is an orally active HDAC inhibitor (IC50= 198 and 157 nM for HDAC1 and HDAC3, respectively), with potential anti-inflammatory, anti-angiogenic, and antineoplastic properties. Uses: Histone deacetylase inhibitors. Synonyms: [6-(diethylaminomethyl)naphthalen-2-yl]methyl N-[4-(hydroxycarbamoyl)phenyl]carbamate; hydrate; hydrochloride; givinostat hydrochloride; ITF 2357; ITF2357; ITF-2357; ITF2357 HCl; ITF2357 hydrochloride. CAS No. 732302-99-7. Molecular formula: C24H27N3O4.HCl.H2O. Mole weight: 475.97. | |
| GK187 | GK187 is a highly potent and selective inhibitor of Group VIA (GVIA) calcium-independent phospholipase A2 (iPLA2). Synonyms: 1,1,1,2,2-pentafluoro-7-(4-methoxyphenyl)-3-heptanone. Grade: ≥95%. CAS No. 1071001-50-7. Molecular formula: C14H15F5O2. Mole weight: 310.26. | |
| GK921 | GK921 is a transglutaminase 2 (TGase 2) inhibitor with average GI50 of 0.9 μM in cancer cell lines. Synonyms: GK921; GK-921; GK 921. Grade: >98%. CAS No. 1025015-40-0. Molecular formula: C21H20N4O. Mole weight: 344.41. | |
| GKA 50 | GKA 50 is a potent glucokinase activator (EC50 = 33 nM). It causes a decrease in plasma glucose levels in diabetic rats and an increase of insulin release from mouse islets of Langerhans. GKA 50 was shown to promote proliferation and prevent apoptosis in rat pancreatic insulinoma-1 beta cell. Synonyms: GKA 50; GKA50; GKA-50; 6-[[3-[(1S)-2-Methoxy-1-methylethoxy]-5-[(1S)-1-methyl-2-phenylethoxy]benzoyl]amino-3-pyridinecarboxylic acid. Grade: ≥98% by HPLC. CAS No. 851884-87-2. Molecular formula: C26H28N2O6. Mole weight: 464.51. | |
| GKK1032B | GKK1032B is a fungal metabolite that has antiproliferative and antibacterial activities. GKK1032B inhibits the growth of HeLa S3 cervical and MCF-7 breast cancer cells and Vero cells. GKK1032B can induce the apoptosis of human osteosarcoma MG63 cells through caspase pathway activation. CAS No. 358375-11-8. Molecular formula: C32H39NO4. Mole weight: 501.67. | |
| GKT137831 | GKT137831 attenuates hypoxia-induced H(2)O(2) release, cell proliferation, and TGF-β1 expression and blunted reductions in PPARγ in HPAECs and HPASMCs. Synonyms: GKT137831; GKT-137831; GKT 137831; GTK831; GTK-831; GTK 831. Grade: >98%. CAS No. 1218942-37-0. Molecular formula: C21H19ClN4O2. Mole weight: 394.85. | |
| GL0388 | GL0388 is a Bax activator, which can lead to Bax insertion into mitochondrial membrane and induce Bax mediated apoptosis. GL0388 has anti-proliferative activity against various cancer cells with IC50s of 0.299-1.57 μM. GL0388 inhibits the growth of breast cancer xenograft tumors in vivo. Synonyms: (E)-2-((3-((2-fluoro-9H-fluoren-9-ylidene)methyl)pyridin-2-yl)oxy)ethan-1-amine. Molecular formula: C21H17FN2O. Mole weight: 332.37. | |
| Glabrescione B | Glabrescione B is the first compound to bind the Hedgehog (Hh) modulator Gli1 and impair its activity by interfering with Gli1-DNA interaction. It inhibits the growth of Hedgehog-dependent tumor cells, the self-renewal ability, and clonogenicity of tumor-derived stem cells. Synonyms: 5,7-Dimethoxy-3',4'-diprenyloxyisoflavone; 4H-1-Benzopyran-4-one, 3-[3,4-bis[(3-methyl-2-buten-1-yl)oxy]phenyl]-5,7-dimethoxy-. Grade: ≥98%. CAS No. 65893-94-9. Molecular formula: C27H30O6. Mole weight: 450.52. | |
| Glabrescone C | Glabrescone C has strong anti-inflammatory activity by directly binding to IKKα/β. Synonyms: (3aR,4R,6aR,9S,9aS,9bS)-6-formyl-9-hydroxy-9-(hydroxymethyl)-3-methylene-2-oxo-2,3,3a,4,6a,7,8,9,9a,9b-decahydroazuleno[4,5-b]furan-4-yl methacrylate. CAS No. 2757214-13-2. Molecular formula: C19H22O7. Mole weight: 362.37. | |
| Glabrolide | Glabrolide is a triterpenoid β-secretase 1 (BACE-1) inhibitor derived from Glycyrrhiza uralensis Fisch. Synonyms: 3β,22β-Dihydroxy-11-oxoolean-12-en-30-oic acid γ-lactone; Olean-12-en-29-oic acid, 3,22-dihydroxy-11-oxo-, gamma-lactone, (3beta,20beta,22beta)-. Grade: ≥95%. CAS No. 10401-33-9. Molecular formula: C30H44O4. Mole weight: 468.67. | |
| Glafenine | Glafenine is a non-steroidal analgesic agent, shows significant antiinflammatory activity. Uses: Wdely used for the treatment of pains of various origins. Synonyms: 2,3-dihydroxypropyl 2-[(7-chloroquinolin-4-yl)amino]benzoate; 1-Glyceryl N-(7-chloro-4-quinolyl)anthranilate. Grade: ≥98%. CAS No. 3820-67-5. Molecular formula: C19H17ClN2O4. Mole weight: 372.80. | |
| Glafenine hydrochloride | Glafenine hydrochloride, an anthranilic acid derivative, is a non-narcotic analgesic and non-steroidal anti-inflammatory drug. It is an ABCG2 inhibitor (IC50 = 3.2 μM). Synonyms: 2,3-dihydroxypropyl 2-[(7-chloroquinolin-4-yl)amino]benzoate; hydrochloride; Glafenine (hydrochloride). CAS No. 65513-72-6. Molecular formula: C19H18Cl2N2O4. Mole weight: 409.26. | |
| Glasdegib | Glasdegib is an orally bioavailable small-molecule inhibitor of the Hedgehog (Hh) signaling pathway that binds to Smoothened (Smo) and inhibits signal transduction. It has been shown to attenuate leukemia stem cell self-renewal and cell cycle progression in primary acute myeloid leukemia cells and in an in vivo Drosophila model. Synonyms: PF-04449913; PF 04449913; 1-[(2R,4R)-2-(1H-benzimidazol-2-yl)-1-methylpiperidin-4-yl]-3-(4-cyanophenyl)urea. Grade: >98%. CAS No. 1095173-27-5. Molecular formula: C21H22N6O. Mole weight: 374.44. | |
| Glatiramer acetate | Glatiramer acetate is an immunomodulator drug currently used to treat multiple sclerosis. It is a random polymer of four amino acids found in myelin basic protein, namely L-glutamic acid, L-lysine, L-alanine, and L-tyrosine. Uses: Multiple sclerosis (ms) is a chronic autoimmune illness that affects the central nervous system. glatiramer acetate is one medicine used to treat ms. glatiramer acetate is primarily used to treat multiple sclerosis (ms), but because of its immunomodulatory qualities and capacity to control inflammatory reactions, scientists have also looked at the possibility of using it in the drug discovery proc. Synonyms: Copaxone; Copolymer 1; Copolymer-1. CAS No. 147245-92-9. Molecular formula: C25H45N5O13. Mole weight: 623.657. | |
| Glatiramer-d7 | Glatiramer-d7 is a labelled Glatiramer. Glatiramer acetate is an immunomodulator drug used for multiple sclerosis. Grade: > 95%. Molecular formula: C25H38N5O13D7. Mole weight: 630.70. | |
| GlcA[3S]b(1-3)Galb(1-4)GlcNAcb(1-2)Mana-Ethylazide | GlcA[3S]b(1-3)Galb(1-4)GlcNAcb(1-2)Mana-Ethylazide is an innovative biomedical product, showcasing remarkable anti-inflammatory and anti-fibrotic effects. Molecular formula: C28H44N4Na20O25S. Mole weight: 1328.52. | |
| GlcNPhth[346Ac]b(1-3)Gal[246Bn]-b-MP | GlcNPhth[346Ac]b(1-3)Gal[246Bn]-b-MP is an innovative compound, finding its applications in studying aberrant cellular proliferation. By selectively antagonizing intricate molecular cascades implicated in the advancement of neoplastic conditions, it emerges as a potent inhibitory compound. Synonyms: 4-Methoxyphenyl 3-O-(3,4,6-Tri-O-acetyl-2-deoxy-2-phthalimido-b-D-glucopyranosyl)-2,4,6-tri-O-benzyl-b-D-galactopyranoside. CAS No. 1820575-44-7. Molecular formula: C54H55NO16. Mole weight: 974.01. | |
| glecaprevir | Glecaprevir is a suppressive agent of hepatitis C virus (HCV). Glecaprevir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 4.09 μM. Uses: The treatment of hepatitis c virus (hcv) infection. Synonyms: ABT 493; (3aR,7S,10S,12R,21E,24aR)-7-tert-butyl-N-[(1R,2R)-2-(difluoromethyl)-1-{[(1-methylcyclopropyl)sulfonyl]carbamoyl}cyclopropyl]-20,20-difluoro-5,8-dioxo-2,3,3a,5,6,7,8,11,12,20,23,24a-dodecahydro-1H,10H-9,12-methanocyclopenta[18,19][1,10,17,3,6]trioxadiazacyclononadecino[11,12-b]quinoxaline-10-carboxamide. Grade: 98%. CAS No. 1365970-03-1. Molecular formula: C38H46F4N6O9S. Mole weight: 838.87. | |
| Glembatumumab | Glembatumumab is a human IgG2 monoclonal antibody directed against the extracellular structural domain of GPNMB expressed in human breast cancer and melanoma. Glembatumumab can be linked to monomethyl auristatin E (MMAE) to form Glembatumumab vedotin, an ADC for cancer therapy. Synonyms: Anti-GPNMB. CAS No. 1020264-78-1. | |
| Glenzocimab | Glenzocimab is an antibody fragment that inhibits the action of platelet glycoprotein VI (GPVI). Glenzocimab has the potential therapeutic effect on acute ischaemic stroke. Synonyms: ACT-017; ACT 017; ACT017. Grade: 95%. CAS No. 2101829-58-5. | |
| Glesatinib | Glasatinib (MGCD265) is a dual MET/SMO inhibitor. Glesatinib is a small molecule, multi-target tyrosine kinase inhibitor with potential anti-tumor activity, which can antagonize P-glycoprotein (P-gp)-mediated multidrug resistance (MDR) in non-small cell lung cancer (NSCLC). Synonyms: MGCD-265; MGCD 265; MGCD265. Grade: ≥98% by HPLC. CAS No. 936694-12-1. Molecular formula: C31H27F2N5O3S2. Mole weight: 619.7. | |
| Glesatinib hydrochloride | The hydrochloride salt form of Glesatinib, an inhibitor of tyrosine kinase, could be effectively targeting tumors that are driving to grow through MET and AXL receptor. It seems to be more common in non-small cell lung cancer and it is still under Phase I. Uses: The hydrochloride salt form of glesatinib could be effectively targeting tumors that are driving to grow through met and axl receptor. Synonyms: MGCD265 hydrochloride; MGCD-265 hydrochloride; MGCD 265 hydrochloride. Grade: 98%. CAS No. 1123838-51-6. Molecular formula: C31H27ClF2N5O3S2X. Mole weight: 655.16. | |
| Gliamilide | Gliamilide is a high-potency Sulfonated urea hypoglycemic agent. Uses: Gliamilide is used as a hypoglycemic agent. Synonyms: CP-27,634; CP 27,634; CP27,634; endo-1-((4-(2-(2-Methoxynicotinamido)ethyl)piperidino)sulfonyl)-3-(5-norbornen-2-ylmethyl)urea. Grade: 98%. CAS No. 51876-98-3. Molecular formula: C23H33N5O5S. Mole weight: 491.61. | |
| Glibenclamide Impurity B | Glibenclamide Impurity B is an impurity in the synthesis of Gyburide. Synonyms: Methyl {{4-{2-[(5-chloro-2-methoxybenzoyl)amino]ethyl}phenyl}sulfonyl}carbamate; N-[[4-[2-[(5-Chloro-2-methoxybenzoyl)amino]ethyl]phenyl]sulfonyl]carbamic Acid Methyl Ester; [[4-[2-[(5-Chloro-2-methoxybenzoyl)amino]ethyl]phenyl]sulfonyl]carbamic Acid Methyl. Grade: > 95%. CAS No. 21165-77-5. Molecular formula: C18H19ClN2O6S. Mole weight: 426.88. | |
| Glibenclamide potassium salt | Glibenclamide potassium salt is a salt form of Glibenclamide, a KATP channel blocker used for the treatment of type 2 diabetes. Glibenclamide binds to and inhibits the sulfonylurea receptor 1 (SUR1), the regulatory subunit of the ATP-sensitive potassium channels (KATP) in pancreatic β cells. Uses: Antidiabetic. Synonyms: Glibenclamide potassium salt; Glyburide potassium salt; 23047-14-5; dipotassium; 5-chloro-N-[2-[4-[(N-cyclohexyl-C-oxidocarbonimidoyl)sulfamoyl]phenyl]ethyl]-2-methoxybenzenecarboximidate; E99010; 5-chloro-N-(4-(N-(cyclohexylcarbamoyl)sulfamoyl)phenethyl)-2-methoxybenzamide potassium. Grade: 99%. CAS No. 23047-14-5. Molecular formula: C23H26ClK2N3O5S. Mole weight: 570.18. | |
| Glibornuride | Glibornuride is an anti-diabetic drug from the group of sulfonylureas. It has been shown to antagonize the relaxant response to the K+ channel opener cromakalim and produce airway smooth muscle relaxation. It is associated with lactic acidosis and hypoglycemia in patients with type 2 diabetes melitus. Uses: Anti-diabetic drug. Synonyms: 1-[(1S,2S,3R,4R)-3-hydroxy-4,7,7-trimethyl-2-bicyclo[2.2.1]heptanyl]-3-(4-methylphenyl)sulfonylurea. Grade: > 98%. CAS No. 26944-48-9. Molecular formula: C18H26N2O4S. Mole weight: 366.476. | |
| Gliclazide D7 | Gliclazide D7 is a deuterium labelled Gliclazide, which is a medication used for the treatment of type 2 diabetes. Grade: 98% HPLC. CAS No. 1188264-75-6. Molecular formula: C15H14N3O3SD7. Mole weight: 330.46. | |
| Gliclazide EP Impurity B | An impurity of Gliclazide. Gliclazide is a second-generation sulfonylurea oral antidiabetic medication primarily used to treat type 2 diabetes by stimulating insulin secretion from pancreatic beta cells and reducing hepatic glucose production. Synonyms: N-Nitroso gliclazide impurity B; Gliclazide Impurity B; 2-Nitroso-octahydrocyclopenta[c]pyrrole; Octahydro-2-nitrosocyclopenta[c]pyrrole; N-Nitroso-3-azabicyclo[3.3.0]octane; 3-Nitroso-3-azabicyclo[3.3.0]octane; N-Nitroso Gliclazide EP Impurity B. Grade: >95%. CAS No. 54786-86-6. Molecular formula: C7H12N2O. Mole weight: 140.19. | |
| Gliclazide EP Impurity G | Gliclazide EP Impurity G is an impurity of Gliclazide. Gliclazide is a whole-cell beta-cell ATP-sensitive potassium currents blocker with an IC50 of 184 nM. Synonyms: N-(p-Tolylsulfonyl)-4,4a,5,6,7,7a-hexahydrocyclopenta[d]pyridazine-3-carboxamide. Grade: > 95%. Molecular formula: C15H19N3O3S. Mole weight: 321.40. | |
| Gliclazide Impurity C | Gliclazide Impurity C is an intermediate in the synthesis of Gliclazide. Synonyms: Tosylurethane; Ethyl (p-Toluenesulfonyl)?carbamate; Ethyl (p-Tolylsulfonyl)?carbamate; Ethyl N-(4-Methylbenzenesulfony?l)?carbamate; Ethyl N-Tosylcarbamate; Ethyl p-Tosylcarbamate; N-Tosylurethane; [(4-methylphenyl)?sulfonyl]?carbamic Acid Ethyl Ester; (p. Grade: > 95%. CAS No. 5577-13-9. Molecular formula: C10H13NO4S. Mole weight: 243.28. | |
| Gliclazide Impurity D | Gliclazide Impurity D. Grade: > 95%. CAS No. 1136426-19-1. Molecular formula: C15H20N2O3S. Mole weight: 308.40. | |
| Gliclazide Impurity (Methyl N-Methyl-p-Tolysulphoncarbomate) | Gliclazide Impurity (Methyl N-Methyl-p-Tolysulphoncarbomate). Grade: > 95%. Molecular formula: C10H13NO4S. Mole weight: 243.28. | |
| Glimepiride-d8 | An isotope labelled of Glimepiride. Glimepiride is an medium-to-long-acting sulfonylurea antidiabetic drug. Grade: 95% by HPLC; 98% atom D. Molecular formula: C24H26D8N4O5S. Mole weight: 498.67. | |
| Glimepiride EP Impurity I | Glimepiride EP Impurity I. Grade: > 95%. Molecular formula: C24H34N4O5S. Mole weight: 490.63. | |
| Glimepiride Ethyl Ester Impurity | Glimepiride Ethyl Ester Impurity. Grade: > 95%. Molecular formula: C19H25N3O6S. Mole weight: 423.49. | |
| Glimepiride Impurity 1 | Glimepiride Impurity 1. Grade: > 95%. Molecular formula: C17H26N4O4S. Mole weight: 382.49. | |
| Glimepiride Impurity A | Glimepiride Impurity A is the cis-isomer of Glimepiride found in a bulk drug substance. Glimepiride is an antidiabetic medication used to treat type 2 diabetes. Synonyms: 1-[[p-[2-(3-Ethyl-4-methyl-2-oxo-3-pyrroline-1-carboxamido)ethyl]phenyl]sulfonyl]-3-(cis-4-methylcyclohexyl)urea; 3-Ethyl-2,5-dihydro-4-methyl-N-[2-[4-[[[[(cis-4-methylcyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-2-oxo-1H-pyrrole-1-carboxamide; Gl. Grade: > 95%. CAS No. 684286-46-2. Molecular formula: C24H34N4O5S. Mole weight: 490.63. | |
| Glimepiride Impurity C | Glimepiride Impurity C is an impurity of Glimepiride. Synonyms: N-[[4-[2-[[(3-Ethyl-2,5-dihydro-4-methyl-2-oxo-1H-pyrrol-1-yl)carbonyl]amino]ethyl]phenyl]sulfonyl]carbamic acid methyl ester; Methyl ((4-(2-(3-ethyl-4-methyl-2-oxo-2,5-dihydro-1H-pyrrole-1-carboxamido)ethyl)phenyl)sulfonyl)carbamate; [[4-[2-[[(3-Ethyl-2,5-. Grade: > 95%. CAS No. 119018-30-3. Molecular formula: C18H23N3O6S. Mole weight: 409.46. | |
| Glimepiride Impurity D | Glimepiride Impurity D. Synonyms: 1-[[m-[2-(3-Ethyl-4-methyl-2-oxo-3-pyrroline-1-carboxamido)ethyl]phenyl]sulfonyl]-3-(trans-4-methylcyclohexyl)urea; 3-Ethyl-2,5-dihydro-4-methyl-N-[2-[3-[[[[(trans-4-methylcyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-2-oxo-1H-pyrrole-1-carboxamid. Grade: > 95%. CAS No. 791104-62-6. Molecular formula: C24H34N4O5S. Mole weight: 490.63. | |
| Glimepiride Impurity E | Glimepiride Impurity E. Synonyms: 3-Ethyl-4-methyl-2-oxo-N-[2-(3-sulphamoylphenyl) ethyl]-2,3-dihydro-1H-pyrrole-1-carboxamide. Grade: > 95%. Molecular formula: C16H21N3O4S. Mole weight: 351.43. | |
| Glimepiride Impurity F | Glimepiride Impurity F. Synonyms: Glimepiride ortho Ester; N-[2-(4-{[(aminocarbonyl)amino]sulfonyl}phenyl)ethyl]-3-ethyl-4-methyl-2-oxo-2,5-dihydro-1H-pyrrole-1-carboxamide. Grade: > 95%. Molecular formula: C18H23N3O6S. Mole weight: 409.46. | |
| Glimepiride Impurity G | Glimepiride Impurity G. Synonyms: Glimepiride N-Methyl Ester; Methyl [[4-[2-[[(3-ethyl-4-methyl-2-oxo-2,3-dihydro-1H-pyrrol-1-yl) carbonyl] amino] ethyl] phenyl] sulphonyl] methylcarbamate. Grade: > 95%. Molecular formula: C19H25N3O6S. Mole weight: 423.49. | |
| Glimepiride Impurity H | Glimepiride Impurity H. Synonyms: Glimepiride Toluene Analog; -[[4-[2-[[(3-Ethyl-4-methyl-2-oxo-2,3-dihydro-1H-pyrrol-1-yl) carbonyl] amino] ethyl] phenyl] sulphonyl]-3-(4-methylphenyl)urea. Grade: > 95%. Molecular formula: C24H28N4O5S. Mole weight: 484.58. | |
| Glimepiride Impurity I | An impurity of Glimepiride, an antidiabetic medication used to treat type 2 diabetes. Synonyms: ortho-Glimepiride Impurity; 3-Ethyl-2,5-dihydro-4-methyl-N-[2-[2-[[[[(trans-4-methylcyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-2-oxo-1H-pyrrole-1-carboxamide; Glimepride 2-Isomer; Glimepiride ortho isomer. Grade: ≥95%. CAS No. 878480-70-7. Molecular formula: C24H34N4O5S. Mole weight: 490.63. | |
| Glimepiride Impurity J | Glimepiride Impurity J. Grade: > 95%. Molecular formula: C16H25N3O3S. Mole weight: 339.46. | |
| Glimepiride meta Ester Impurity | Glimepiride meta Ester Impurity. Grade: > 95%. Molecular formula: C18H23N3O6S. Mole weight: 409.46. | |
| Glioroseinol | Glioroseinol is a fungal metabolite of gliorosein originally isolated from Gliocladium. Synonyms: 4S-hydroxy-2,3-dimethoxy-5S,6S-dimethylcyclohex-2-en-1-one. Grade: >95% by HPLC. Molecular formula: C10H16O4. Mole weight: 200.23. | |
| Glipizide | Glipizide is an oral rapid- and short-acting anti-diabetic drug from the sulfonylurea class. Glipizide is used to treat high blood sugar levels caused by a type of diabetes mellitus called type 2 diabetes. Uses: Hypoglycemic agents. Synonyms: 2-Pyrazinecarboxamide, N-[2-[4-[[[(cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-5-methyl-; N-[2-[4-[[[(Cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-5-methyl-2-pyrazinecarboxamide; Pyrazinecarboxamide, N-[2-[4-[[[(cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-5-methyl-; Urea, 1-cyclohexyl-3-[[p-[2-(5-methylpyrazinecarboxamido)ethyl]phenyl]sulfonyl]-; Aldiab; CP 28720; Digrin; Dipazide; Glibenese; Glibetin; Glican; Glidiab; Glipid; Glipizid; Gluco-Rite; Glucolip; Glucotrol; Glucotrol Xl; Glucozide; Glupitel; Glupizide; Glyde; Glydiazinamide; Glynase; K 4024; Melizide; Mindiab; Minidab; Minidiab; Minodiab; N-(4-[β-(5-Methylpyrazine-2-carboxamido)ethyl]benzenesulfonyl)-N'-cyclohexylurea; Napizide; Ozidia; Samarium(III) ionophore I; Semiglynase; Sucrazide; TK 1320. Grade: >98%. CAS No. 29094-61-9. Molecular formula: C21H27N5O4S. Mole weight: 445.54. | |
| Glipizide Carbamate Impurity | Glipizide Carbamate Impurity. Grade: > 95%. Molecular formula: C18H27N3O5S. Mole weight: 397.50. | |
| Glipizide Dimer | Glipizide Dimer is a biomedicine product used to study type 2 diabetes. Grade: > 95%. Molecular formula: C28H28N7O6S2K. Mole weight: 661.81. | |
| Glipizide EP Impurity C | Glipizide EP Impurity C is an impurity formed during the synthesis of Glipizide. Glipizide is an oral rapid- and short-acting anti-diabetic drug from the sulfonylurea class. Synonyms: N-Des(5-methylpyrazinecarbonyl)-N-ethylcarboxyl Glipizide; Ethyl 4-(N-(cyclohexylcarbamoyl)sulfamoyl)phenethylcarbamate. CAS No. 13554-93-3. Molecular formula: C18H27N3O5S. Mole weight: 397.49. | |
| Glipizide EP Impurity D | Glipizide EP Impurity D is an intermediate in the synthesis of the impurity 5-Desmethyl-6-methyl Glipizide. Synonyms: 6-Methyl-N-[2-(4-sulphamoylphenyl)ethyl]pyrazine-2-carboxamide; N-Des(cyclohexylaMinocarbonyl) Glipizide; 4-[β-(6-Methylpyrazinyl-2-carboxamido)ethyl]benzene Sulfonamide; N-[2-[4-(Aminosulfonyl)phenyl]ethyl]-6-methyl-2-pyrazinecarboxamide; 4-[2-(6-Methylpyra. Grade: > 95%. CAS No. 1346600-54-1. Molecular formula: C14H16N4O3S. Mole weight: 320.37. | |
| Glipizide EP Impurity E | Glipizide EP Impurity E. Synonyms: 1-Cyclohexyl-3-{{4-{2-{[(6-methylpyrazin-2-yl)carbonyl]amino}ethyl}phenyl}sulfonyl}urea; 5-Desmethyl-6-methyl Glipizide; N-[2-[4-[[[(Cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-6-methyl-2-pyrazinecarboxamide. Grade: > 95%. CAS No. 66375-96-0. Molecular formula: C21H27N5O4S. Mole weight: 445.54. | |
| Glipizide EP Impurity F | Glipizide EP Impurity F is a glipizide impurity. Synonyms: [2-[4-(AMinosulfonyl)phenyl]ethyl]carbaMic Acid Ethyl Ester. Grade: > 95%. CAS No. 192118-08-4. Molecular formula: C11H16N2O4S. Mole weight: 272.33. | |
| Glipizide EP Impurity G | Glipizide EP Impurity G is an intermediate in the synthesis of Glipizide. Synonyms: N-[4-[β-(5-Methylpyrazine-2-carboxaMido)ethyl]phenylsulfonyl]Methylurethane; Methyl 4-[β-(5-Methylpyrazine-2-carboxaMido)ethyl]benzene SulfonaMide CarbaMate; N-[[4-[2-[[(5-Methyl-2-pyrazinyl)carbonyl]aMino]ethyl]phenyl]sulfonyl]carbaMic Acid Methyl Ester. Grade: > 95%. CAS No. 33288-74-3. Molecular formula: C16H18N4O5S. Mole weight: 378.41. | |
| Glipizide EP Impurity H | Glipizide EP Impurity H is an impurity of Glipizide. Synonyms: 1-Cyclohexyl-3-(p-sulfaMoylphenethyl)urea; 4-[2-[[(CyclohexylaMino)carbonyl]aMino]ethyl]benzenesulfonaMide. Grade: > 95%. CAS No. 10080-05-4. Molecular formula: C15H23N3O3S. Mole weight: 325.43. | |
| Glipizide EP Impurity I | Glipizide EP Impurity I is an impurity of Glipizide. Synonyms: 1-Cyclohexyl-3-(p-sulfaMoylphenethyl)urea; 4-[2-[[(CyclohexylaMino)carbonyl]aMino]ethyl]benzenesulfonaMide; N-[4-(β-Cyclohexylureidoethyl)benzensulfonyl] N'-Cyclohexylurea; N-[(Cyclohexylamino)carbonyl]-4-[2-[[(cyclohexylamino)carbonyl]amino]ethyl]- benzenes. Grade: > 95%. CAS No. 10079-35-3. Molecular formula: C22H34N4O4S. Mole weight: 450.60. | |
| Glipizide EP Impurity J | Glipizide EP Impurity J is an impurity formed during the synthesis of Glipizide. Glipizide is an oral rapid- and short-acting anti-diabetic drug from the sulfonylurea class. Uses: An intermediate in the synthesis of glipizide. Synonyms: N-[[4-[2-[[(5-Methyl-2-pyrazinyl)carbonyl]amino]ethyl]phenyl]sulfonyl]carbamic Acid Ethyl Ester; N-[[4-[2-[[(5-Methyl-2-pyrazinyl)carbonyl]amino]ethyl]phenyl]sulfonyl]carbamic Acid Ethyl Ester. Grade: 95%. CAS No. 1076198-09-8. Molecular formula: C17H20N4O5S. Mole weight: 392.43. | |
| Glipizide Ethyl Carbonate Impurity | Glipizide Ethyl Carbonate Impurity. Grade: > 95%. Molecular formula: C17H20N4O5S. Mole weight: 392.44. | |
| Glipizide Impurity 4 | Glipizide Impurity 4 is an impurity formed during the synthesis of Glipizide. Glipizide is an oral rapid- and short-acting anti-diabetic drug from the sulfonylurea class. Synonyms: Isopropyl ((4-(2-(5-methylpyrazine-2-carboxamido)ethyl)phenyl)sulfonyl)carbamate. CAS No. 2468797-13-7. Molecular formula: C18H22N4O5S. Mole weight: 406.46. | |
| Glipizide Isopropyl Carbonate Impurity | Glipizide Isopropyl Carbonate Impurity. Grade: > 95%. Molecular formula: C18H22N4O5S. Mole weight: 406.46. | |
| Glipizide Related Compound A | Glipizide Related Compound A is an intermediate in the synthesis of Glipizide. Synonyms: 4-[2-(5-Methylpyrazine-2-carboxamido)ethyl]benzenesulfonamide; N-{2-[4-(Aminosulfonyl)phenyl]ethyl}-5-methyl-2-pyrazinecarboxamide; 2-[4-Aminosulfonyl-phenyl]-ethyl-5-methylpyrazinecarboxamide; 4-[β-(5-Methylpyrazinyl-2-carboxamido)ethyl]benzene Sulfonamide. Grade: > 95%. CAS No. 33288-71-0. Molecular formula: C14H16N4O3S. Mole weight: 320.37. | |
| Glisoxepide | Glisoxepide, a second-generation sulfonylurea, exerts greater binding affinity than the first-generation compounds. With antihyperglycemic activity, Glisoxepide is used as an antidiabetic drug used in the treatment of diabetes mellitus type 2. Uses: Antidiabetic. Synonyms: N-[2-[4-[[[[(Hexahydro-1H-azepin-1-yl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-5-methyl-3-isoxazolecarboxamide; 4-[4-[β-(5-Methylisoxazole-3-carboxamido)ethyl]phenylsulfonyl]-1,1-hexamethylenesemicarbazide; BS 4231; BS4231; BS-4231; Glisepin; Glisoxepide; Pro-Diaban. Grade: 95%. CAS No. 25046-79-1. Molecular formula: C20H27N5O5S. Mole weight: 449.52. | |
| GLL398 | GLL398 is an orally active selective estrogen receptor degrader (SERD) that competitively binds to the estrogen receptor (IC50 = 1.14 nM), and blocks tumor growth in xenograft breast cancer models. It has a strong dose-dependent binding profile for the ER with a Y537S point mutation (IC50 = 29.5 nM). Synonyms: (2E)-3-(4-{1-[4-(Dihydroxyboryl)phenyl]-2-phenyl-1-buten-1-yl}phenyl)acrylic acid; 2-Propenoic acid, 3-[4-[1-(4-boronophenyl)-2-phenyl-1-buten-1-yl]phenyl]-, (2E)-. Grade: ≥95%. CAS No. 2077980-80-2. Molecular formula: C25H23BO4. Mole weight: 398.26. | |
| [Gln4]-Neurotensin | Neurotensin induces contractions in smooth muscle cells, playing a role in regulating digestive activity in vitro and in vivo. Synonyms: 4-Gln-neurotensin; H-Pyr-Leu-Tyr-Gln-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH. Grade: 98%. CAS No. 61445-54-3. Molecular formula: C78H122N22O19. Mole weight: 1671.9. | |
| Gln(Acm)4-AVP | Gln(Acm)4-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: Gln(Acm)-Vasopressin; Gln(Acm)4-Vasopressin; H-Cys-Tyr-Phe-Gln(Acm)-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl(Acm)-L-asparagyl-L-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-disulfide. Molecular formula: C49H70N16O13S2. Mole weight: 1155.32. | |
| Gln(Acm)-Desmopressin | Gln(Acm)-Desmopressin is an impurity of Desmopressin, which is a synthetic octapeptide and an analog of the human hormone arginine vasopressin with antidiuretic and coagulant activities. Synonyms: Deamino-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl(Acm)-L-asparagyl-L-cysteinyl-L-prolyl-D-arginyl-glycinamide (1->6)-disulfide; deamino-Cys-Tyr-Phe-Gln(Acm)-Asn-Cys-Pro-D-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); Mpr-Tyr-Phe-Gln(Acm)-Asn-Cys-Pro-D-Arg-Gly-NH2 (Disulfide Bridge Mpr1-Cys6); [Gln(Acm)]4-Desmopressin; Gln4(Acm)-Desmopressin; N5.4-[(Acetylamino)methyl]desmopressin; Desmopressin EP Impurity E. Grade: ≥95%. Molecular formula: C49H69N15O13S2. Mole weight: 1140.30. | |
| Gln-AMS TFA | Gln-AMS is a type Ia aminoacyl-tRNA synthetase (AARS) inhibitor. Gln-AMS inhibits glutaminyl-tRNA synthetase (GlnRS) with a Ki of 1.32 μM. Grade: 98%. Molecular formula: C17H23F3N8O10S. Mole weight: 588.47. | |
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