BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Globo-H-b-N-acetyl propargyl | Globo-H-b-N-acetyl propargyl is a groundbreaking biomedical compound, unveiling its prowess in the research of malignant neoplasms. Exerting its profound inhibitory effect, it precisely disarms the intricate molecular networks dictating the relentless proliferation and metastasis of cancerous cells. Synonyms: Fuc-a-1,2-Gal-b-1,3-GalNAc-b-1,3-Gal-a-1,4-Gal-b-1,4-Glc-b-NAc-Prop. Molecular formula: C43H70N2O30. Mole weight: 1095.01. |  |
| Globo-H BSA conjugate | Globo-H BSA conjugate. | |
| Globohexaosylceramide | Globohexaosylceramide is an intricate carbohydrate-derived compound, finding its application as a research tool in unraveling mysteries pertaining to specific ailments such as cancer. Synonyms: Ceramide, 1-O-[O-6-deoxy-α-L-galactopyranosyl-(1→2)-O-β-D-galactopyranosyl-(1→3)-O-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl-(1→3)-O-α-D-galactopyranosyl-(1→4)-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl]-; Ganglioside GA3, O-6-deoxy-α-L-galactopyranosyl-(1→2)-O-β-D-galactopyranosyl-(1→3)-O-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl-(1→3)-O-α-D-galactopyranosyl-(1→4B)-; Globo H; Globo-H hexaose. Grade: 90%. CAS No. 77538-31-9. | |
| Globo H (hexassacharide) | Globo-H is a prominently employed bioactive glycolipid antigen, serving as a pivotal compound in the exploration of cancer and immunotherapy. It finds primary application in the research of vaccines and targeted approaches for drug dissemination. Synonyms: Fuc-a-1,2-Gal-b-1,3-GalNAc-b-1,3-Gal-a-1,4-Gal-b-1,4-Glc; alpha-L-Fucp-(1->2)-beta-D-Galp-(1->3)-beta-D-GalpNAc-(1->3)-alpha-D-Galp-(1->4)-beta-D-Galp-(1->4)-beta-D-Glcp; alphaFuc(1-2)betaGal(1-3)betaGalNAc(1-3)alphaGal(1-4)betaGal(1-4)betaGlc. CAS No. 207384-96-1. Molecular formula: C38H65NO30. Mole weight: 1015.91. | |
| Globo H pentenyl glycoside | Globo H pentenyl glycoside. CAS No. 284663-02-1. Molecular formula: C43H73NO30. Mole weight: 1084.03. | |
| Globoisotetraose | Globoisotetraose is an extensively utilized synthetic compound, showcasing considerable potential in the precise targeting of tumor-associated carbohydrate antigens, with specific emphasis on the Globo H antigen, for the research of cancer. Synonyms: Isoglobotetraose; O-2-(Acetylamino)-2-deoxy-b-D-galactopyranosyl-(1→3)-O-a-D-galactopyranosyl-(1→3)-O-b-D-galactopyranosyl-(1→4)-D-glucose. CAS No. 75645-26-0. Molecular formula: C26H45NO21. Mole weight: 707.63. | |
| Globomycin | Globomycin is a lipopeptide antibiotic and signal peptidase II (LspA) inhibitor from Streptomyces hagronensis that inhibits the growth of enteric Gram-negative bacteria by inhibiting cell wall synthesis. It inhibits the processing of prolipoprotein by irreversibly binding to peptidase. Uses: Protease inhibitors. Synonyms: Antibiotic SF-1902A1; Cyclo[Gly-[(2R,3R)-3-hydroxy-2-methyl-1-oxononyl]-N-methyl-L-Leu-L-aIle-L-Ser-L-aThr-]; SF-1902A1; Glycine, N-(N-(N-(N-(N-(3-hydroxy-2-methyl-1-oxononyl)-N-methylleucyl)-L-alloisoleucyl)-L-seryl)-L-allothreonyl)-, rho-lactone; SF 1902. Grade: ≥95%. CAS No. 67076-74-8. Molecular formula: C32H57N5O9. Mole weight: 655.82. | |
| Globo-N-tetraose | Globo-N-tetraose is a potential compound exhibiting promising properties in the research of cancer, specifically in targeting cancer cells expressing the Globo H antigen. By blocking the interaction between Globo H and corresponding antibodies, Globo-N-tetraose shows potential as an antitumor compound. Synonyms: GalNAc-b-1,3-Gal-a-1,4-Gal-b-1,4-Glc; O-2-(Acetylamino)-2-deoxy-β-D-galactopyranosyl-(1→3)-O-α-D-galactopyranosyl-(1→4)-O-β-D-galactopyranosyl-(1→4)-D-glucose; Globotetraose; N-((2S,3R,4R,5R,6R)-2-(((2R,3R,4S,5S,6R)-2-(((2R,3R,4R,5R,6S)-4,5-Dihydroxy-2-(hydroxymethyl)-6-(((2R,3R,4R,5R)-1,2,4,5-tetrahydroxy-6-oxohexan-3-yl)oxy)tetrahydro-2H-pyran-3-yl)oxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl)oxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)acetamide. CAS No. 75660-79-6. Molecular formula: C26H45NO21. Mole weight: 707.63. | |
| Globo-N-tetraose-APD-HSA | Globo-N-tetraose-APD-HSA. | |
| Globo-N-tetraose GEL | Globo-N-tetraose GEL. | |
| Globopentaose | Globopentaose is a remarkable carbohydrate compound used for studying gastrointestinal afflictions, ranging from the debilitating grasp of inflammatory bowel syndrome to the treacherous clutches of bacterial invasions. Synonyms: Gal-b-1,3-GalNAc-b-1,3-Gal-a-1,4-Gal-b-1,4-Glc; SSEA-3a. CAS No. 71937-76-3. Molecular formula: C32H55NO26. Mole weight: 869.77. | |
| Globoside | Globoside is a glycosphingolipid abundantly present in human erythrocytes and diverse tissues, exhibiting multifaceted roles as a microbial toxin receptor and a regulator of cell adhesion and signal transduction. Synonyms: Globotetraosylceramide; Cytolipins; GlcNAc (b1-3)Gal (a1-4) Gal (b1-4) Glc b1-1 Cer; 1-O-[O-2-(Acetylamino)-2-deoxy-β-D-galactopyranosyl-(1→3)-O-α-D-galactopyranosyl-(1→4)-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl]-ceramide; Cytolipin K; CQH; CQH (globoside); Ganglioside Gb4; Ganglioside GL 4; Gb4; Gb4Cer; Globo-N-tetraosylceramide; Globoside (human erythrocytes); Globoside Gb 4; Globoside GL 4; Globoside I; Globosidic acid; Globotetraosylceramide; Parvovirus B19 receptor; Tetrahexosylceramide. CAS No. 11034-93-8. | |
| Globotriaosylceramide | Globotriaosylceramide is a synthetic compound utilized for studying Anderson-Fabry disease. Acting as a substrate for enzymes, it aids in the research of this lysosomal storage disorder. Synonyms: Gb3; a-D-Gal-(1→4)-b-D-Gal-(1→4)-b-D-Glc-1→O-ceramide; Ceramide trihexosides; 1-O-(O-α-D-Galactopyranosyl-(1→4)-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl)ceramide; CD 77; Ceramide trihexoside; CTH; Fabry glycolipid; Ganglioside Gb3; Ganglioside GL3; Gb3Cer; Globo-N-triaosylceramide; Globotriglycosylceramide; Globotriosylceramide; Shiga toxin receptor; Trihexosylceramide; alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(d18:1/24:0). CAS No. 71965-57-6. Molecular formula: C14H20N6O5S. Mole weight: 384.41. | |
| Globotriaosylceramid?e Sphingosine-d2,13C tert-Butyldimethylsilyl | Globotriaosylceramid?e Sphingosine-d2,13C tert-Butyldimethylsilyl is a labeled Fabry disease biomarker. Synonyms: (2S,?3R,?4E)?-2-Amino-3-((tert-butyldimethylsilyl)oxy)-4-octadecenyl-d2,13C O-α-D-Galactopyranosyl-(1→4)?-O-β-D-galactopyranosyl-(1→4)?-β-D-glucopyranoside; lyso-Gb3-d2,13C tert-Butyldimethylsilyl; (2R,3R,4S,5R,6R)-2-(((2R,3R,4R,5R,6S)-6-(((2R,3S,4R,5R,6R)-6-(((2S,3R,E)-2-Amino-3-((tert-butyldimethylsilyl)oxy)octadec-4-en-1-yl-d2, 13C)oxy)-4,5-dihydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-4,5-dihydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol. Molecular formula: C41[13C]H79D2NO17Si. Mole weight: 903.18. | |
| Globotriaosylsphingosine | Globotriaosylsphingosine, or Gb3, is a crucial biomarker used in the biomedical industry to diagnose and monitor the progression of Fabry disease. This rare genetic disorder results from the deficiency of a specific enzyme, leading to the abnormal accumulation of Gb3 within various organs. Precise and sensitive detection of Gb3 helps physicians determine the severity of Fabry disease and devise personalized treatment plans accordingly. Synonyms: a-D-Gal-(1→4)-b-D-Gal-(1→4)-b-D-Glc-1→O-sphingosine; Lysoglobotriaosylceramide; Ceramide trihexoside; lysoGb3; (2S,3R,4E)-2-Amino-3-hydroxy-4-octadecen-1-yl O-α-D-galactopyranosyl-(1→4)-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranoside; β-D-Glucopyranoside, (2S,3R,4E)-2-amino-3-hydroxy-4-octadecenyl O-α-D-galactopyranosyl-(1→4)-O-β-D-galactopyranosyl-(1→4)-; Globotriaosylceramide sphingosine; lyso-Gb3. Grade: >99%. CAS No. 126550-86-5. Molecular formula: C36H67NO17. Mole weight: 785.91. | |
| Globotriose | Globotriose is a carbohydrate product used in biomedicine to study the role of glycolipids in various diseases and drug development. It is commonly utilized as a mimic to study the biological interactions with globotriaosylceramide (Gb3), which is involved in the progression of certain infections, such as E. coli and Shiga toxin-producing bacteria. Globotriose provides valuable insights into the development of therapeutics targeting Gb3-mediated diseases. Synonyms: 4-O-(4-O-α-D-Galactopyranosyl-β-D-galactopyranosyl)-D-glucose; Gal-a-1,4-Gal-b-1,4-Glc; pk-Antigen; Globotriaose; O-α-D-Galactopyranosyl-(1→4)-O-β-D-galactopyranosyl-(1→4)-D-glucose; alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-D-Glc; alpha-D-Galp-(1->4)-beta-D-Galp-(1->4)-D-Glcp. Grade: ≥95%. CAS No. 66580-68-5. Molecular formula: C18H32O16. Mole weight: 504.44. | |
| Globotriose 2-(2-carboxyethylthio)ethane | Globotriose 2-(2-carboxyethylthio)ethane is an extensively employed compound, serving as a cornerstone for research purposes in various ailments including hemolytic uremic syndrome and Escherichia coli-induced bacterial infections. Synonyms: 2-(2-Carboxyethylthio)-ethyl 4-O-[4-O(a-D-galactopyranosyl)-b-D-galactopyranosyl]-b-D-glucopyranoside. Molecular formula: C23H40O18S. Mole weight: 636.62. | |
| Globotriose-APE-HSA | Globotriose-APE-HSA. | |
| Globotriose-GEL | Globotriose-GEL. | |
| Globotriose-HSA | Globotriose-HSA. | |
| Globotriose-HSA (3 atom spacer) | Globotriose-HSA (3 atom spacer) is a potential therapeutic agent used in the treatment of shiga toxin-producing E. coli infections. It comprises a synthetic molecule made of three sugar molecules connected to human serum albumin with a three-atom spacer. The compound can bind to the shiga toxin produced by E. coli, preventing it from attaching to cell receptors and causing damage to vital organs. Synonyms: Globotriose-HSA conjugate, 3 Atom spacer; Gal(a1-4)Gal(b1-4)Glc-HSA (3 atom spacer); alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-D-Glc-HSA (3 atom spacer); O-α-D-Galactopyranosyl-(1→4)-O-β-D-galactopyranosyl-(1→4)-D-glucose-HSA (3 atom spacer). | |
| Glofitamab | Glofitamab is a T-cell-engaging bispecific antibody possessing a novel 2:1 structure with bivalency for CD20 on B cells and monovalency for CD3 on T cells. Glofitamab is used as an effective therapy for relapsed or refractory diffuse large B-cell lymphoma. Synonyms: RO7082859; RG6026. CAS No. 2229047-91-8. | |
| GLP-1(28-36)amide acetate | GLP-1(28-36)amide acetate inhibits mitochondrial permeability transition with antioxidant, anti-diabetic and cardioprotection activities. Molecular formula: C56H89N15O11. Mole weight: 1148.40. | |
| GLP-1 (7-36) amide trifluoroacetate salt | GLP-1 (7-36) amide is an important peptide hormone that displays a strong insulinotropic effect. It binds the GLP-1 receptor (pIC50 = 8.5) in the pancreas and shows various antidiabetic effects. Synonyms: Glucagon-like Peptide 1 (7-36) amide. Mole weight: 3297.6. | |
| GLP-1 (9-36) amide | GLP-1 (9-36) amide is an N-terminal truncated metabolite of glucagon-like peptide GLP-1-(7-36) formed by dipeptidyl peptidase-IV cleavage. GLP-1 (9-36) amide functions as a human GLP-1 receptor antagonist. Synonyms: Glucagon-like peptide-1 (9-36) amide; Glucagon-like peptide-1 (9 36) amide. CAS No. 161748-29-4. Molecular formula: C140H214N36O43. Mole weight: 3089.44. | |
| GLP-1 antagonist | A glucagon-like peptide-1 (GLP-1) receptor antagonist. Synonyms: GLP-1 antagonist; GLP 1 antagonist; N-[[4,5-dimethyl-1-[(2-methylphenyl)methyl]imidazol-2-yl]methyl]-2,4-dimethoxy-N-(3-methylbutyl)benzamide. Grade: 99%. CAS No. 475466-57-0. Molecular formula: C28H37N3O3. Mole weight: 463.61. | |
| GLP-1R agonist DMB | GLP-1R agonist DMB is a glucagon-like peptide-1 (GLP-1) receptor agonist used potentially for the treatment of type 2 diabetes. Uses: Potential treatment of type 2 diabetes. Synonyms: N-(tert-Butyl)-6,7-dichloro-3-(methylsulfonyl)quinoxalin-2-amine. Grade: 99%. CAS No. 281209-71-0. Molecular formula: C13H15Cl2N3O2S. Mole weight: 348.25. | |
| GLP-1 receptor agonist 2 | GLP-1 receptor agonist 2 is an agonist of glucagon-like peptide-1 receptor (GLP-1R). Synonyms: 1H-Benzimidazole-6-carboxylic acid, 2-[[(2S)-4-[6-[(4-chloro-2-fluorophenyl)methoxy]-2-pyridinyl]-2-methyl-1-piperazinyl]methyl]-1-[(2S)-2-oxetanylmethyl]-; 2-{[(2S)-4-{6-[(4-Chloro-2-fluorobenzyl)oxy]-2-pyridinyl}-2-methyl-1-piperazinyl]methyl}-1-[(2S)-2-oxetanylmethyl]-1H-benzimidazole-6-carboxylic acid. Grade: ≥95%. CAS No. 2230197-64-3. Molecular formula: C30H31ClFN5O4. Mole weight: 580.05. | |
| GLP-1 receptor agonist 3 | GLP-1 receptor agonist 3 is a GLP-1 receptor agonist with EC50s of 1.1 and 13 nM in Clone H6 and Clone C6 cell lines assay, respectively. (Extracted from patent WO2018109607A1, Example 4A-1). Synonyms: 1H-Benzimidazole-6-carboxylic acid, 2-[[4-[6-[(4-cyano-2-fluorophenyl)methoxy]-2-pyridinyl]-1-piperidinyl]methyl]-1-[(2R)-2-oxetanylmethyl]-; 2-[(4-{6-[(4-Cyano-2-fluorobenzyl)oxy]-2-pyridinyl}-1-piperidinyl)methyl]-1-[(2R)-2-oxetanylmethyl]-1H-benzimidazole-6-carboxylic acid. Grade: ≥95%. CAS No. 2230200-09-4. Molecular formula: C31H30FN5O4. Mole weight: 555.60. | |
| GLP-1 receptor agonist 4 | GLP-1 receptor agonist 4, a glucagon-like peptide-1 receptor (GLP-1R) agonist with an EC50 of 64.5 nM, can be used in the study of diabetes treatment. (Extracted from patent WO2009111700A2, compound 87). Synonyms: (S)-3-(4'-Cyano-[1,1'-biphenyl]-4-yl)-2-((3R,8S)-3-(4-((3,4-dichlorobenzyl)oxy)phenyl)-1-methyl-2-oxo-7-((S)-1-phenylpropyl)-2,3,6,7,8,9-hexahydro-1H-[1,4]oxazino[3,2-g]isoquinoline-8-carboxamido)propanoic acid; (2S)-3-(4'-Cyano-4-biphenylyl)-2-[({(3R,8S)-3-{4-[(3,4-dichlorobenzyl)oxy]phenyl}-1-methyl-2-oxo-7-[(1S)-1-phenylpropyl]-2,3,6,7,8,9-hexahydro-1H-[1,4]oxazino[3,2-g]isoquinolin-8-yl}carbonyl)amino]propanoic acid. Grade: ≥95%. CAS No. 1187061-62-6. Molecular formula: C51H44Cl2N4O6. Mole weight: 879.82. | |
| GLP-1 receptor agonist 7 | GLP-1 receptor agonist 7 is a potent glucagon-like peptide-1 (GLP-1) agonist with potential to study GLP-1-related diseases, disorders and conditions, including diabetes mellitus. (Extracted from patent WO2021219019A1, compound 130b). Synonyms: 2-((4-((S)-3-(4-chloro-2-fluorophenyl)-2,3-dihydrobenzo[b][1,4]dioxin-5-yl)piperidin-1-yl)methyl)-3-(((S)-oxetan-2-yl)methyl)-3H-imidazo[4,5-b]pyridine-5-carboxylic acid. CAS No. 2736447-04-2. Molecular formula: C31H30ClFN4O5. Mole weight: 593.05. | |
| GLP-1 receptor agonist 8 | GLP-1 receptor agonist 8, a potent GLP-1 receptor agonist, has potential in the study of diabetes, obesity and non-alcoholic fatty liver disease (NAFLD). (Extracted from patent WO2019239319A1, compound 17). Synonyms: ammonium (R)-2-((4-(2-(4-chloro-2-fluorophenyl)-2-methylbenzo[d][1,3]dioxol-4-yl)piperidin-1-yl)methyl)-1-((1-ethyl-1H-imidazol-5-yl)methyl)-1H-benzo[d]imidazole-6-carboxylate. CAS No. 2401892-86-0. Molecular formula: C34H36ClFN6O4. Mole weight: 647.14. | |
| GLP-1 receptor agonist 9 | GLP-1 receptor agonist 9 is an agonist of GLP-1 receptor. (Extracted from WO2020234726 A1, example 7). Synonyms: 1H-Benzimidazole-6-carboxylic acid, 2-[[4-[(2S)-2-(4-chloro-2-fluorophenyl)-2-methyl-1,3-benzodioxol-4-yl]-1-piperidinyl]methyl]-1-[(2S)-2-oxetanylmethyl]-. Grade: ≥95%. CAS No. 2401892-71-3. Molecular formula: C32H31ClFN3O5. Mole weight: 592.06. | |
| GLP-1 receptor agonist 9 citrate | GLP-1 receptor agonist 9 is an agonist of GLP-1 receptor. Molecular formula: C38H39ClFN3O12. Mole weight: 784.18. | |
| GLP-1R modulator C16 | GLP-1R modulator C16 is an allosteric modulator that enhances the binding of GLP-1 to GLP-1R through transmembrane site with an EC50 of 8.43±3.82 μM. Synonyms: N-{4-[(2-chloro-6-fluorobenzyl)oxy]-3-methoxybenzyl}-N-[2-(4-morpholinyl)ethyl]amine; N-{4-[(2-Chloro-6-fluorobenzyl)oxy]-3-methoxybenzyl}-2-(4-morpholinyl)ethanamine; 4-Morpholineethanamine, N-[[4-[(2-chloro-6-fluorophenyl)methoxy]-3-methoxyphenyl]methyl]-. Grade: ≥90%. CAS No. 875005-43-9. Molecular formula: C21H26ClFN2O3. Mole weight: 408.89. | |
| GLP-1R modulator C5 | GLP-1R modulator C5 is an allosteric modulator that enhances the binding of GLP-1 to GLP-1R through transmembrane site with an EC50 of 1.59±0.53 μM. Synonyms: 3-hydroxy-3-(2-oxo-2-phenylethyl)-1-(2-phenylethyl)-1,3-dihydro-2H-indol-2-one; 2H-Indol-2-one, 1,3-dihydro-3-hydroxy-3-(2-oxo-2-phenylethyl)-1-(2-phenylethyl)-. Grade: ≥90%. CAS No. 421578-93-0. Molecular formula: C24H21NO3. Mole weight: 371.43. | |
| GLP-1R modulator L7-028 | GLP-1R modulator L7-028 is an allosteric modulator that enhances the binding of GLP-1 to GLP-1R through transmembrane site with an EC50 of 11.01±2.73 μM. Synonyms: Benzamide, 3-(cyclopentyloxy)-N-[3-(1-piperidinylcarbonyl)phenyl]-. Grade: ≥95%. CAS No. 2648317-95-5. Molecular formula: C24H28N2O3. Mole weight: 392.49. | |
| GLP-26 | GLP-26 is an HBV capsid assembly modulator (CAM) that inhibits HBV DNA replication (IC50 = 3 nM) in Hep AD38 system and reduces cccDNA by >90% at 1 μM. GLP-26 disrupts pregenomic RNA encapsulation, leading to nucleocapsid disintegration and reduced cccDNA pools. Synonyms: N-(3,4-Difluorophenyl)-1,3,5-trimethyl-4-(2-oxo-2-(prop-2-yn-1-ylamino)acetyl)-1H-pyrrole-2-carboxamide; N-(3,4-Difluorophenyl)-1,3,5-trimethyl-4-[oxo(2-propyn-1-ylamino)acetyl]-1H-pyrrole-2-carboxamide; 1H-Pyrrole-3-acetamide, 5-[[(3,4-difluorophenyl)amino]carbonyl]-1,2,4-trimethyl-α-oxo-N-2-propyn-1-yl-. Grade: ≥98%. CAS No. 2133017-36-2. Molecular formula: C19H17F2N3O3. Mole weight: 373.35. | |
| GLP-2 (rat) trifluoroacetate salt | GLP-2 is a gut peptide hormone that is primarily produced by enteroendocrine L cells of the small and large intestine. GLP-2 is an antagonist of the GLP-2 receptor (GLP-2R; Ki = 60 pM). Synonyms: Glucagon-like Peptide 2. Grade: ≥95%. Molecular formula: C166H256N44O56S·xCF3COOH. Mole weight: 3796.14. | |
| GLPG-0187 | GLPG-0187 is a small molecule integrin receptor antagonist (IRA) with nanomolar affinity for the RGD-integrin receptors αvβ1, αvβ3, αvβ5, αvβ6 and α5β1 (IC50s = 1.2-3.7 nM). Integrin receptors are expressed on the surface of tumor vessel endothelial cells and some types of cancer cells, and play a crucial role in endothelial cell adhesion and migration. This compound shows an inhibitory activity of angiogenesis, bone-resorption and tumor, which is hopefully used as an anticancer drug. Uses: An integrin receptor antagonist (ira) can be used as an anticancer drug. Synonyms: GLPG0187; GLPG 0187; GLPG-0187; UNII-43A5P87Z4T; 43A5P87Z4T; SCHEMBL2372722; CHEMBL3319236; (2S)-3-[[2,5-dimethyl-6-[4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)piperidin-1-yl]pyrimidin-4-yl]amino]-2-[(4-methoxyphenyl)sulfonylamino]propanoic acid. Grade: ≥98 %. CAS No. 1320346-97-1. Molecular formula: C29H37N7O5S. Mole weight: 595.719. | |
| GLPG0492 | GLPG0492, a selective androgen receptor modulator, could be effective in decreasing muscle loss. The treatment study against Duchenne muscular dystrophy of it has alreadt been discontinued. Uses: Glpg0492 is a selective androgen receptor modulator that could be effective in decreasing muscle loss. Synonyms: DT-200; DT 200; DT200; GLPG0492; SCHEMBL2021011; CHEMBL2178100; GLPG 0492; GLPG-0492; VAJGULUVTFDTAS-GOSISDBHSA-N. Grade: 98%. CAS No. 1215085-92-9. Molecular formula: C19H14F3N3O3. Mole weight: 389.33. | |
| GLPG0492 R enantiomer | The R-enantiomer of GLPG0492 which is a selective androgen receptor modulator, could be effective in decreasing muscle loss. Uses: The r-enantiomer of glpg0492 which is a selective androgen receptor modulator that could be effective in decreasing muscle loss. Synonyms: GLPG-0492 R enantiomer; GLPG 0492 R enantiomer; GLPG0492 R enantiomer. Grade: 98%. CAS No. 1215085-93-0. Molecular formula: C19H14F3N3O3. Mole weight: 389.33. | |
| GLPG0634 analogue | A potent and selective JAK1 inhibitor with IC50 values of 10, 28, 810, and 116 nM for JAK1, JAK2, JAK3, and TYK2, respectively. Synonyms: GLPG0634 analog; N-[5-[4-[(6-cyanopyridin-3-yl)methoxy]phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide. Grade: >98%. CAS No. 1206101-20-3. Molecular formula: C23H18N6O2. Mole weight: 410.43. | |
| GLPG 0974 | GLPG 0974 is a potent FFA2 antagonist (IC50 = 9 nM) with selectivity for FFA2 over FFA3. It was shown that GLPG 0974 inhibited acetate-induced human neutrophil migration in plasma or buffer, and also suppressed FFA2-induced expression of CD11b activation-specific epitope (AE) in human whole blood. Synonyms: GLPG0974; GLPG 0974; GLPG-0974. 4-[[[(2R)-1-(Benzo[b]thien-3-ylcarbonyl)-2-methyl-2-azetidinyl]carbonyl][(3-chlorophenyl)methyl]amino]butanoic acid. Grade: ≥98% by HPLC. CAS No. 1391076-61-1. Molecular formula: C25H25ClN2O4S. Mole weight: 485. | |
| GLPG-1690 | GLPG-1690, an imidazopyridine derivative, has been found to be a selective autotaxin inhibitor that could probably be effective as an anti-inflammatory agent and is under Phase II trial against Idiopathic pulmonary fibrosis (IPF). Synonyms: Ziritaxestat; GLPG 1690; GLPG1690; 2-((2-ethyl-6-(4-(2-(3-hydroxyazetidin-1-yl)-2-oxoethyl)piperazin-1-yl)-8-methylimidazo[1,2-a]pyridin-3-yl)(methyl)amino)-4-(4-fluorophenyl)thiazole-5-carbonitrile. Grade: >98%. CAS No. 1628260-79-6. Molecular formula: C30H33FN8O2S. Mole weight: 588.71. | |
| GLPG1837 | GLPG1837 is a potent, orally available potentiator of cystic fibrosis transmembrane conductance regulator (CFTR) with EC50 of 3 nM and 339 nM on F508del and G551D CFTR, respectively. Synonyms: ABBV-974; N-[3-(aminocarbonyl)-4,7-dihydro-5,5,7,7-tetramethyl-5H-thieno[2,3-c]pyran-2-yl]-1H-pyrazole-3-carboxamide. Grade: ≥98%. CAS No. 1654725-02-6. Molecular formula: C16H20N4O3S. Mole weight: 348.42. | |
| GLPG2938 | GLPG2938 is a potent and selective S1P2 antagonist that can be used for the study of idiopathic pulmonary fibrosis. It inhibits S1P-induced calcium flux in CHO cells overexpressing human S1P2 (IC50 = 8.8 nM), inhibits S1P-induced IL-8 release in HFL1 cells (IC50 = 0.6 nM) and S1P-induced contraction of human lung fibroblasts. Synonyms: 1-(2-Ethoxy-6-(trifluoromethyl)pyridin-4-yl)-3-((5-methyl-6-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)pyridazin-3-yl)methyl)urea; MUN96006; 1-[2-Ethoxy-6-(trifluoromethyl)-4-pyridinyl]-3-({5-methyl-6-[1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-3-pyridazinyl}methyl)urea; Urea, N-[2-ethoxy-6-(trifluoromethyl)-4-pyridinyl]-N'-[[5-methyl-6-[1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-3-pyridazinyl]methyl]-. Grade: ≥98%. CAS No. 2130996-00-6. Molecular formula: C20H19F6N7O2. Mole weight: 503.40. | |
| Glu-14-Calcitonin | Glu-14-Calcitonin is an impurity of Calcitonin salmon, which is a calcium regulating hormone used to be an effective alternative for the treatment of postmenopausal osteoporosis. Synonyms: H-Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Glu-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2 (Disulfide bond between Cys1 and Cys7); L-cysteinyl-L-seryl-L-asparagyl-L-leucyl-L-seryl-L-threonyl-L-cysteinyl-L-valyl-L-leucyl-glycyl-L-lysyl-L-leucyl-L-seryl-L-alpha-glutamyl-L-alpha-glutamyl-L-leucyl-L-histidyl-L-lysyl-L-leucyl-L-glutaminyl-L-threonyl-L-tyrosyl-L-prolyl-L-arginyl-L-threonyl-L-asparagyl-L-threonyl-glycyl-L-seryl-glycyl-L-threonyl-L-prolinamide (1->7)-disulfide; RPR 108969; Calcitonin (salmon), 14-L-glutamic acid-. CAS No. 187476-38-6. Molecular formula: C145H239N43O49S2. Mole weight: 3432.88. | |
| Glu-20-Calcitonin | Glu-20-Calcitonin is an impurity of Calcitonin salmon, which is a calcium regulating hormone used to be an effective alternative for the treatment of postmenopausal osteoporosis. Synonyms: H-Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Glu-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2 (Disulfide bond between Cys1 and Cys7); L-cysteinyl-L-seryl-L-asparagyl-L-leucyl-L-seryl-L-threonyl-L-cysteinyl-L-valyl-L-leucyl-glycyl-L-lysyl-L-leucyl-L-seryl-L-glutaminyl-L-alpha-glutamyl-L-leucyl-L-histidyl-L-lysyl-L-leucyl-L-alpha-glutamyl-L-threonyl-L-tyrosyl-L-prolyl-L-arginyl-L-threonyl-L-asparagyl-L-threonyl-glycyl-L-seryl-glycyl-L-threonyl-L-prolinamide (1->7)-disulfide; RPR 108970; Calcitonin (salmon), 20-L-glutamic acid-. CAS No. 187476-39-7. Molecular formula: C145H239N43O49S2. Mole weight: 3432.88. | |
| Glu4,Asp5,Gly9-Oxytocin | Glu4,Asp5,Gly9-Oxytocin is a modified analog of oxytocin with specific amino acid substitutions and modifications. Oxytocin is a peptide hormone and neuropeptide that plays crucial roles in various physiological processes. Oxytocin is best known for its functions in childbirth and lactation, where it helps to stimulate uterine contractions during labor and milk ejection during breastfeeding. Synonyms: Cys-Tyr-Ile-Glu-Asp-Cys-Pro-Leu-Gly(Cys1&Cys6 bridge); Glu4,Asp5,Gly9-OH-Oxytocin; 4-Glu-5-Asp-9-Gly-OH-oxytocin; L-Cysteinyl-L-tyrosyl-L-isoleucyl-L-alpha-glutamyl-L-alpha-aspartyl-L-cysteinyl-L-prolyl-L-leucyl-glycine (1->6)-disulfide; Oxytocin, 4-glutamic acid-5-aspartic acid-9-glycine; 3-((4R,7S,10S,13S,16S,19R)-19-Amino-13-((S)-sec-butyl)-7-(carboxymethyl)-4-((S)-2-(((S)-1-((carboxymethyl)amino)-4-methyl-1-oxopentan-2-yl)carbamoyl)pyrrolidine-1-carbonyl)-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-10-yl)propanoic acid; [Glu4,Asp5,Gly9]-Oxytocin. Grade: >95%. Molecular formula: C43H63N9O15S2. Mole weight: 1010.15. | |
| Glu4,Asp5-Oxytocin | Glu4,Asp5-Oxytocin is a modified analog of oxytocin where the amino acids at positions 4 and 5 are altered. Specifically, glutamic acid (Glu) is introduced at position 4, and aspartic acid (Asp) is introduced at position 5. These modifications can significantly influence the biological activity and pharmacological properties of the peptide. Synonyms: Cys-Tyr-Ile-Glu-Asp-Cys-Pro-Leu-Gly-NH2(Cys1&Cys6 bridge); 4-Glu-5-Asp-oxytocin; L-Cysteinyl-L-tyrosyl-L-isoleucyl-L-alpha-glutamyl-L-alpha-aspartyl-L-cysteinyl-L-prolyl-L-leucyl-glycinamide (1->6)-disulfide; 3-((4R,7S,10S,13S,16S,19R)-19-Amino-4-((S)-2-(((S)-1-((2-amino-2-oxoethyl)amino)-4-methyl-1-oxopentan-2-yl)carbamoyl)pyrrolidine-1-carbonyl)-13-((S)-sec-butyl)-7-(carboxymethyl)-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-10-yl)propanoic acid; Oxytocin [4-Glu,5-Asp]; [Glu4,Asp5]-Oxytocin; Oxytocin Impurity 18. Grade: >95%. CAS No. 2092497-01-1. Molecular formula: C43H64N10O14S2. Mole weight: 1009.16. | |
| Glu(4)-AVP | Glu4-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: Glu(4)-Arg-Vasopressin; Glu(4)-Vasopressin; Glu4-AVP; H-Cys-Tyr-Phe-Glu-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutamyl-L-asparagyl-L-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-disulfide. CAS No. 2075712-12-6. Molecular formula: C46H64N14O13S2. Mole weight: 1085.22. | |
| Glu4-Carbetocin | An impurity of Carbetocin. Carbetocin is a long-acting analogue of the hormone oxytocin, used primarily to control postpartum hemorrhage and to induce uterine contractions. Synonyms: cyclo(Butyryl-Tyr(Me)-Ile-Glu-Asn-Cys)-Pro-Leu-Gly-NH2; Glu3-Carbetocin; Glu(4)-Carbetocin; [Glu4]-Carbetocin; [L-Glu4]-Carbetocin; Carbetocin Impurity 3; [Glu4] Carbetocin; Carbetocin Glu impurity; 1-Carbaoxytocin, 1-butanoic acid-2-(O-methyl-L-tyrosine)-4-L-glutamic acid-; But-Tyr(Me)-Ile-Glu-Asn-Cys-Pro-Leu-Gly-NH2 (Thioether bridge: But1-Cys6); Butyryl-O-methyl-L-tyrosyl-L-isoleucyl-L-alpha-glutamyl-L-asparagyl-L-cysteinyl-L-prolyl-L-leucyl-glycinamide (1->6)-thioether. Grade: ≥95%. CAS No. 69228-04-2. Molecular formula: C45H68N10O13S. Mole weight: 989.15. | |
| Glu 4-Oxytocin | Glu 4-Oxytocin is an impurity of Oxytocin, which is a mammalian neurohypophysial hormone used as a vasodilator agent. Synonyms: [4-Glutamic acid]oxytocin; L-Cystyl-L-tyrosyl-L-isoleucyl-L-glutamyl-L-asparginyl-L-cystyl-L-leucyl-L-prolyl-L-glycinamide (disulfide bridge between cysteines); H-Cys-Tyr-Ile-Glu-Asn-Cys-Pro-Leu-Gly-NH2 (Disulfide bridge: Cys1-Cys6); [Glu4]-Oxytocin; L-Cysteinyl-L-tyrosyl-L-isoleucyl-L-alpha-glutamyl-L-asparagyl-L-cysteinyl-L-prolyl-L-leucyl-glycinamide (1->6)-disulfide; Oxytocin, 4-L-glutamic acid-; Oxytocin, 4-glutamic acid; 4-L-glutamic acid-Oxytocin; Oxytocin EP Impurity C; Glu4-Oxytocin; Cys-Tyr-Ile-Glu-Asn-Cys-Pro-Leu-Gly-NH2(Cys1&Cys6 bridge); CYIENCPLG-NH2(Cys1&Cys6 bridge). Grade: ≥95%. CAS No. 4314-67-4. Molecular formula: C43H65N11O13S2. Mole weight: 1008.18. | |
| Glu7,Gly12-Terlipressin | An impurity of Terlipressin. Terlipressin is a synthetic vasopressin analogue primarily used to improve kidney function in adults with hepatorenal syndrome (HRS), a condition that causes kidney problems in individuals with severe liver disease. It acts as a vasoconstrictor, predominantly in the splanchnic circulation, which helps increase arterial pressure and reduce portal venous pressure. Synonyms: Gly-Gly-Gly-Cys-Tyr-Phe-Glu-Asn-Cys-Pro-Lys-Gly(Cys4&Cys9 bridge); [7-L-glutamic acid,12-glycine]terlipressin; Terlipressin EP Impurity K; GGGCYFENCPKG(Cys4&Cys9 bridge); H-Gly-Gly-Gly-Cys-Tyr-Phe-Glu-Asn-Cys-Pro-Lys-Gly-OH (Disulfide bridge: Cys4-Cys9); Glycyl-glycyl-glycyl-L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-α-glutamyl-L-asparagyl-L-cysteinyl-L-prolyl-L-lysyl-glycine (4->9)-disulfide; [Glu(7), Gly(12)]-Terlipressin [Glu(7)-TLY-COOH]; [Glu7, Gly12]-Terlipressin. Grade: ≥95%. Molecular formula: C52H72N14O17S2. Mole weight: 1229.35. | |
| Glu7-Terlipressin | An impurity of Terlipressin. Terlipressin is a synthetic vasopressin analogue primarily used to improve kidney function in adults with hepatorenal syndrome (HRS), a condition that causes kidney problems in individuals with severe liver disease. It acts as a vasoconstrictor, predominantly in the splanchnic circulation, which helps increase arterial pressure and reduce portal venous pressure. Synonyms: Gly-Gly-Gly-Cys-Tyr-Phe-Glu-Asn-Cys-Pro-Lys-Gly-NH2(Cys4&Cys9 bridge); [7-L-glutamic acid]terlipressin; Terlipressin EP Impurity F; [8-L-α-aspartic acid]terlipressin; H-Gly-Gly-Gly-Cys-Tyr-Phe-Glu-Asn-Cys-Pro-Lys-Gly-NH2 (Disulfide bridge: Cys4-Cys9); Glycyl-glycyl-glycyl-L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-α-glutamyl-L-asparagyl-L-cysteinyl-L-prolyl-L-lysyl-glycinamide (4->9)-disulfide; Glu(7)-Terlipressin; [Glu7]-Terlipressin; GGGCYFENCPKG-NH2(Cys4&Cys9 bridge). Grade: ≥95%. Molecular formula: C52H73N15O16S2. Mole weight: 1228.37. | |
| Glu-Asp-OH | Glu-Asp-OH is a dipeptide used as a diagnostic indicator of the disease. Synonyms: L-α-Glutamyl-L-aspartic acid; Vesilute; (S)-2-((S)-2-Amino-4-carboxybutanamido)succinic acid. Grade: ≥ 98% (TLC). CAS No. 3918-84-1. Molecular formula: C9H14N2O7. Mole weight: 262.22. | |
| Glubionate Calcium | Glubionate Calcium is a mineral supplement. It can be used to prevent or treat low blood calcium levels. Synonyms: Calcium glubionate; Neocalglucon; Calcium, (4-O-β-D-galactopyranosyl-D-gluconato)(D-gluconato)-, monohydrate; D-Gluconic acid, 4-O-β-D-galactopyranosyl-, calcium complex; D-Gluconic acid, calcium complex; Calcium glucono-galacto-gluconate; Calcium gluconolactobionate; Gluconogalactogluconic acid, calcium salt; Hi-Glucon; Neo-Calglucon. CAS No. 12569-38-9. Molecular formula: C18H32CaO19.H2O. Mole weight: 610.53. | |
| Glucagon (19-29), human acetate | Glucagon (19-29), human acetate, a COOH-terminal fragment processed from glucagon, is a potent and efficient inhibitor of insulin secretion. Molecular formula: C63H93N15O20S. Mole weight: 1412.57. | |
| Glucagon Receptor Antagonist I | Glucagon receptor antagonist I is a potent and competitive antagonist of the glucagon receptor (GCGR) with an IC50 value of 181 nM. Synonyms: GCGR Antagonist I; hGCGR Antagonist; N-[3-cyano-6-(1,1-dimethylpropyl)-4,5,6,7-tetrahydrobenzo[b]thien-2-yl]-2-ethyl-butanamide. Grade: ≥99%. CAS No. 438618-32-7. Molecular formula: C20H30N2OS. Mole weight: 346.5. | |
| Glucagon receptor antagonists 1 | Glucagon receptor antagonists-1 is a highly potent glucagon receptor antagonist, which is activated by glucagon and is a member of the class B G-protein coupled family of receptors. Uses: Glucagon receptor antagonist. Synonyms: glucagon receptor antagonists 1; 1-(4-(2-(Benzyloxy)-4-fluorophenyl)-2,6-diisopropyl-5-(prop-1-en-1-yl)pyridin-3-yl)ethanol; 1-[4-(4-fluoro-2-phenylmethoxyphenyl)-2,6-di(propan-2-yl)-5-[(E)-prop-1-enyl]pyridin-3-yl]ethanol. Grade: ≥95%. CAS No. 503559-84-0. Molecular formula: C29H34FNO2. Mole weight: 447.59. | |
| glucagon receptor antagonists-2 | glucagon receptor antagonists-2 is a highly potent antagonist of glucagon receptor. Synonyms: glucagon receptor antagonists 2; (6E)-3-fluoro-6-[3-[(1R)-1-hydroxyethyl]-2,6-di(propan-2-yl)-5-propyl-1H-pyridin-4-ylidene]cyclohexa-2,4-dien-1-one3-Pyridinemethanol, 4-(4-fluoro-2-hydroxyphenyl)-a-methyl-2,6-bis(1-methylethyl)-5-propyl-, (aR)-. CAS No. 202917-18-8. Molecular formula: C22H30FNO2. Mole weight: 359.48. | |
| glucagon receptor antagonists-3 | glucagon receptor antagonists-3 is a highly potent antagonist of glucagon receptor. Synonyms: glucagon receptor antagonists 3; 3-Pyridinemethanol, 4-(4-fluoro-2-hydroxyphenyl)-a-methyl-2,6-bis(1-methylethyl)-5-propyl-, (aR,4R)-rel- (9CI); (aphlaR,4R)-4-(4-Fluoro-2-hydroxyphenyl)-alpha-methyl-2,6-bis(1-methylethyl)-5-propyl-3-pyridinemethanol. CAS No. 202917-17-7. Molecular formula: C22H30FNO2. Mole weight: 359.48. | |
| glucagon receptor antagonists-4 | glucagon receptor antagonists-4 is a potent glucagon receptor antagonist with great oral bioavailability in vivo. Synonyms: PF-06291874; PF 06291874; PF06291874; PF-6291874; PF 6291874; PF6291874; glucagon receptor antagonists 4; β-Alanine, N-[4-[(1S)?-1-[3,?5-dimethyl-4-[4-(trifluoromethyl)?-1H-pyrazol-1-yl]?phenoxy]?butyl]?benzoyl]?-. CAS No. 1393124-08-7. Molecular formula: C26H28F3N3O4. Mole weight: 503.51. | |
| Glucagon receptor antagonists-5 | Glucagon receptor antagonists-5 is a potent and orally bioavailable indazole-based glucagon receptor antagonist (Ki = 32?nM) with potential for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: (S)-3-(4-(1-(5-(2-Chloro-4-(trifluoromethyl)phenyl)-6-methyl-1H-indazol-1-yl)-3-methylbutyl)benzamido)propanoic acid; N-{4-[(1S)-1-{5-[2-Chloro-4-(trifluoromethyl)phenyl]-6-methyl-1H-indazol-1-yl}-3-methylbutyl]benzoyl}-β-alanine. Grade: ≥95%. CAS No. 2200274-63-9. Molecular formula: C30H29ClF3N3O3. Mole weight: 572.02. | |
| Glucocorticoid receptor agonist | Glucocorticoid receptor agonist is an effective Glucocorticoid receptor agonist and probably has steroid-like anti-inflammatory properties. Uses: Glucocorticoid receptor agonist is an effective glucocorticoid receptor agonist and probably has steroid-like anti-inflammatory properties. Synonyms: 4-fluoro-2-[(4R)-5,5,5-trifluoro-4-hydroxy-2-methyl-4-(1H-pyrrolo[2,3-c]pyridin-2-ylmethyl)pentan-2-yl]phenol; Glucocorticoidreceptoragonist; CHEMBL1253898; 1245526-82-2; C20H20F4N2O2; 3695AH. Grade: 95%. CAS No. 1245526-82-2. Molecular formula: C20H20F4N2O2. Mole weight: 396.38. | |
| Glucocorticoid receptor agonist-1 | Glucocorticoid receptor agonist-1 is a potent agonist of glucocorticoid receptor with an IC50 of 2.8 nM. (Extracted from patent WO2017210471A1, compound 41). Synonyms: Pregna-1,4-diene-3,20-dione, 16,17-[[(R)-[4-[(3-aminophenyl)methyl]phenyl]methylene]bis(oxy)]-11,21-dihydroxy-, (11β,16α)-. CAS No. 2166375-82-0. Molecular formula: C35H39NO6. Mole weight: 569.69. | |
| Glucocorticoid receptor modulator-1 | A glucocorticoid receptor modulator. Synonyms: EX-A5386. CAS No. 2452396-89-1. Molecular formula: C29H27FN4O2. Mole weight: 482.55. | |
| Glucocorticoids receptor agonist 1 | Glucocorticoids receptor agonist 1 is a potent and arylpyrazole-based glucocorticoid receptor agonist with anti-inflammatory activity. It does not impair insulin secretion. Synonyms: N-Arylpyrazolo[3,2-c]-Based Ligand, 26; (1S)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4aH,5H,6H,7H,8H-cyclohexa[f]indazol-5-yl]ethan-1-ol; (1S)-1-[(4aR,5S)-1-(4-Fluorophenyl)-4a-methyl-4,4a,5,6,7,8-hexahydro-1H-benzo[f]indazol-5-yl]ethanol; 1H-Benz[f]indazole-5-methanol, 1-(4-fluorophenyl)-4,4a,5,6,7,8-hexahydro-α,4a-dimethyl-, (αS,4aR,5S)-. CAS No. 694526-54-0. Molecular formula: C20H23FN2O. Mole weight: 326.41. | |
| Glucocorticoids receptor agonist 2 | Glucocorticoids receptor agonist 2 is a potent and arylpyrazole-based glucocorticoid receptor agonist with anti-inflammatory activity. It does not impair insulin secretion. Synonyms: (R)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4aH,5H,6H,7H,8H-cyclohexa[f]indazol-5-yl](phenyl)methanol; (R)-[(4aR,5S)-1-(4-Fluorophenyl)-4a-methyl-4,4a,5,6,7,8-hexahydro-1H-benzo[f]indazol-5-yl](phenyl)methanol; 1H-Benz[f]indazole-5-methanol, 1-(4-fluorophenyl)-4,4a,5,6,7,8-hexahydro-4a-methyl-α-phenyl-, (αR,4aR,5S)-; N-Arylpyrazolo[3,2-c]-Based Ligand, 10. CAS No. 614761-20-5. Molecular formula: C25H25FN2O. Mole weight: 388.48. | |
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