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Gemcitabine elaidate hydrochloride
Gemcitabine elaidate is a lipophilic prodrug form of the nucleoside analog gemcitabine that contains an elaidic acid moiety. Gemcitabine elaidate inhibits growth of gemcitabine-sensitive L1210/L5, BCLO, and A2780 cells (IC50s = 0.0033, 0.0042, and 0.0025 μM, respectively) but not cytarabine-resistant L4A6 and Bara-C cells (IC50s = 16 and 13 μM, respectively) or gemcitabine-resistant AG6000 cells (IC50 = 91 μM). Synonyms: CO-101 hydrochloride; CP-4126 hydrochloride; Gemcitabine 5'-elaidate hydrochloride. Grade: ≥97%. CAS No. 2918768-08-6. Molecular formula: C27H44ClF2N3O5. Mole weight: 564.11.
Gemcitabine hydrochloride
Gemcitabine induced NF-κB activity in BxPC-3, PANC-1, and MIA PaCa-2 cells and decreased the level of the NF-κB inhibitor IκBα in BxPC-3 and PANC-1 cells. Uses: Antimetabolites, antineoplastic. Synonyms: Gemzar; Gemcitabine HCl; LY188011 hydrochloride. Grade: >98%. CAS No. 122111-03-9. Molecular formula: C9H11F2N3O4.HCI. Mole weight: 299.66.
A monophosphorylated derivative of Gemcitabine and has been found to exhibit potent activities as a cytotoxic agent and induce apoptosis. Synonyms: 2',2'-difluorodeoxycytidine Monophosphate; Gemcitabine 5'-phosphate. Grade: ≥ 95 % by HPLC. CAS No. 116371-67-6. Molecular formula: C9H12F2N3O7P. Mole weight: 343.18.
Gemcitabine monophosphate disodium salt
Gemcitabine monophosphate disodium salt is a derivative of gemcitabine. Gemcitabine, under the trade name Gemzar, is a chemotherapy drug for the treatment of various cancers. Gemcitabine is used as a first-line medication for pancreatic cancer. Synonyms: Gemcitabine monophosphate disodium salt monohydrate; Gemcitabine monophosphate disodium; GemMP. CAS No. 1638288-31-9. Molecular formula: C9H12F2N3Na2O8P. Mole weight: 405.158.
Gemcitabine Triphosphate
Gemcitabine Triphosphate is a compelling antineoplastic compound, holding immense potential in studying a multitude of cancers such as non-small cell lung cancer, pancreatic cancer and ovarian cancer. Its innovative mechanism inhibits DNA synthesand repair, thus effectively hindering the growth and propagation of malignant cells. Synonyms: 2',2'-Difluorodeoxycytidine 5'-triphosphate; dFdCTP. CAS No. 110988-86-8. Molecular formula: C9H14F2N3O13P3. Mole weight: 503.14.
Gemcitabine Triphosphate Ditriethylamine
Gemcitabine Triphosphate is a Gemcitabine phosphorylated metabolite, an antineoplastic agent. Synonyms: Cytidine 5'-(tetrahydrogen triphosphate), 2'-deoxy-2',2'-difluoro-, compd. with N,N-diethylethanamine (1:2); 2'-Deoxy-2',2'-difluorocytidine 5'-(Tetrahydrogen Triphosphate) Di(N,N-diethylethanamine); Gemcitabine Triphosphate di(triethylamine) Salt. Grade: 97%. Molecular formula: C21H44F2N5O13P2. Mole weight: 705.52.
Gemcitabine Triphosphate (triethylammonium salt form)
An impurity of Gemcitabine. Gemcitabine is an antineoplastic chemotherapy medication of the antimetabolites class. It halts cell division through damaging RNA or DNA which control the process. It can be used to treat multiple cancers. Synonyms: Cytidine 5'-(tetrahydrogen triphosphate), 2'-deoxy-2',2'-difluoro-, compd. with N,N-diethylethanamine (1:3); 2'-Deoxy-2',2'-difluorocytidine 5'-(Tetrahydrogen Triphosphate) triethylammonium; Gemcitabine Triphosphate Tri(triethylamine) Salt. Grade: 95%. CAS No. 1035495-84-1. Molecular formula: C9H14F2N3O13P3.3C6H15N. Mole weight: 806.71.
Gemfibrozil
Gemfibrozil is the generic name for an oral drug used to lower lipid levels. It belongs to a group of drugs known as fibrates. It is most commonly sold as the brand name, Lopid. Other brand names include Jezil and Gen-Fibro. Synonyms: CI-719; CI 719; CI719. Grade: >98%. CAS No. 25812-30-0. Molecular formula: C15H22O3. Mole weight: 250.33.
Gemfibrozil Acyl-beta-D-Glucuronide
Gemfibrozil Acyl-beta-D-Glucuronide is the major metabolite of Gemfibrozil. It can be oxidized to a benzyl radical intermediate which binds to the γ-meso position of heme. Synonyms: 1-[5-(2,5-Dimethylphenoxy)-2-dimethylpentanoate] b-D-glucopyranuronic acid. Grade: > 95%. CAS No. 91683-38-4. Molecular formula: C21H30O9. Mole weight: 426.47.
Gemfibrozil b-D-glucuronide-[d6]
Gemfibrozil b-D-glucuronide-[d6] is a remarkable compound of immense significance, finding its purpose in the therapeutic research of cardiovascular disorders. Specifically tailored to study the levels of cholesterol and triglycerides, this compound manifests its influence as a distinguished PPAR-alpha agonist. Synonyms: 1-[5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoate] b-D-glucopyranuronic acid; Gemfibrozil b-D-glucuronide-D6. Molecular formula: C21H24D6O9. Mole weight: 432.49.
Gemfibrozil EP Impurity I
An impurity of Gemfibrozil. Gemfibrozil is a fibrate lipid-regulating agent used primarily to treat hypertriglyceridemia and reduce the risk of cardiovascular events. Synonyms: Gemfibrozil methyl ester; Pentanoic acid, 5-(2,5-dimethylphenoxy)-2,2-dimethyl-, methyl ester; Gemfibrozil impurity I [EP]; Gemfibrozil Impurity I; 5-(2,5-Dimethylphenoxy)-2,2-dimethyl-pentanoic acid methyl ester. CAS No. 149105-25-9. Molecular formula: C16H24O3. Mole weight: 264.36.
Gemfibrozil Related Compound A is a derivative of Gemfibrozil. Synonyms: (E,Z)-2,2-dimethyl-5-[2,5-dimethyl-4-(propene-1-yl)phenoxy]valeric acid; 5-[2,5-Dimethyl-4-(1-propen-1-yl)phenoxy]-2,2-dimethylpentanoic acid; 4-(1-Propenyl) Gemfibrozil. Grade: > 95%. CAS No. 500904-61-0. Molecular formula: C18H26O3. Mole weight: 290.41.
Gemfibrozil Related Compound D
Gemfibrozil Related Compound D is a biomedical product used in the research of hyperlipidemia. It exhibits properties similar to Gemfibrozil, an FDA-approved drug. Synonyms: 6-Propenyl Gemfibrozil (Mixture of Z and E Isomers). Grade: > 95%. Molecular formula: C18H26O3. Mole weight: 290.41.
Gemifloxacin Impurity
Gemifloxacin Impurity is an Gemifloxacin impurity, Third generation fluorinated quinolone antibacterial. Synonyms: Desmethoxyamino Hydroxy Gemifloxacin; 7-(3-(Aminomethyl)-4-hydroxypyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic Acid. Grade: > 95%. CAS No. 213672-25-4. Molecular formula: C17H19FN4O4. Mole weight: 362.36.
Gemifloxacin mesylate
Gemifloxacin mesylate, a fluoroquinolone, is an oral broad-spectrum antibacterial agent that has shown strong activity in vitro against a variety of respiratory tract pathogens for the treatment of mild to moderate pneumonia. Synonyms: 1,8-Naphthyridine-3-carboxylic acid, 7-[(4Z)-3-(aminomethyl)-4-(methoxyimino)-1-pyrrolidinyl]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-, monomethanesulfonate; Factive; Floxguard; Gemixa; LB 20304a; SB 265805S; 7-[(4Z)-3-(aminomethyl)-4-(methoxyimino)-1-pyrrolidinyl]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-Naphthyridine-3-carboxylic Acid Monomethanesulfonate; (Z)-Gemifloxacin Mesilate. Grade: ≥95%. CAS No. 210353-53-0. Molecular formula: C19H24FN5O7S. Mole weight: 485.50.
Gemifloxacin Related Compound 1
Gemifloxacin Related Compound 1 is an impurity of Gemifloxacin, an antibiotic drug commonly used to treat respiratory tract infections, such as bronchitand pneumonia. Grade: > 95%. Molecular formula: C18H20FN5O4. Mole weight: 389.39.
Gemifloxacin Related Compound 2
Gemifloxacin Related Compound 2 is an impurity of gemifloxacin, a drug for treating an array of bacterial afflictions encompassing respiratory and urinary tract infections. Grade: > 95%. Molecular formula: C17H17FN4O4. Mole weight: 360.35.
Gemigliptin
Gemigliptin is a potent dipeptidyl peptidase-4 (DPP-4) inhibitor with the potential use in diabetes treatment. Synonyms: 1-[(2S)-2-amino-4-[2,4-bis(trifluoromethyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-7-yl]-4-oxobutyl]-5,5-difluoropiperidin-2-one. CAS No. 911637-19-9. Molecular formula: C18H19F8N5O2. Mole weight: 489.37.
Gemilukast
This active molecular is an potent dual Leukotriene CysLT1 and CysLT2 Receptor antagonist originated by Ono Pharmaceutical. IC50 values is 1.7nM against human CysLT1 and 25 nM against human CysLT2. Gemilukast reduced LTC4-induced bronchoconstriction in asthmatic animal models dose-dependently. In addition, it can also reduceantigen-induced constriction of isolated human bronchi. In 2015, Phase-II clinical trials in Asthma in Japan and USA was on-going. Uses: Asthma. Synonyms: ONO6950; ONO 6950; ONO-6950; 4,4'-(4-fluoro-7-((4-(4-(3-fluoro-2-methylphenyl)butoxy)phenyl)ethynyl)-2-methyl-1H-indole-1,3-diyl)dibutyric acid; 1232861-64-1 (disodium salt); 1232873-69-6 (8 hydrate and disodium salt). Grade: 98%. CAS No. 1232861-58-3. Molecular formula: C36H37F2NO5. Mole weight: 601.69.
Gemilukast 8 hydrate and disodium salt).
Gemilukast 8 hydrate and disodium salt is an exceptional compound harnessed to studying inflammatory ailments, such as asthma and allergic rhinitis. Synonyms: 1H-Indole-1,?3-dibutanoic acid, 4-fluoro-7-[2-[4-[4-(3-fluoro-2-methylphenyl)?butoxy]?phenyl]?ethynyl]?-2-methyl-, sodium salt, hydrate (1:2:8). Grade: 98%. CAS No. 1232873-69-6. Molecular formula: C36H37F2NO5.8H2O.2Na. Mole weight: 601.69.
Gemilukast disodium salt
Gemilukast, also known as ONO-6950, is an orally active dual CysLT1 and CysLT2 antagonist. Gemilukast exhibited antagonist activities with IC50 values of 1.7 and 25 nM against human CysLT1 and human CysLT2, respectively. Synonyms: 1H-Indole-1,?3-dibutanoic acid, 4-fluoro-7-[2-[4-[4-(3-fluoro-2-methylphenyl)?butoxy]?phenyl]?ethynyl]?-2-methyl-, sodium salt (1:2). Grade: 98%. CAS No. 1232861-64-1. Molecular formula: C36H37F2NO5.2Na. Mole weight: 647.67.
Gemnelatinib
Gemnelatinib is a tyrosine kinase inhibitor, with antineoplastic activity. Synonyms: (3R)-25-fluoro-3,81-dimethyl-26-oxo-26H-6-oxa-5(2,5)-pyrimidina-1(2),2(3,1)-dipyridina-8(4)-piperidina-4(1,3)-benzenaoctaphane-14-carbonitrile; (R)-5'-fluoro-1'-(1-(3-(5-((1-methylpiperidin-4-yl)methoxy)pyrimidin-2-yl)phenyl)ethyl)-6'-oxo-1',6'-dihydro-[2,3'-bipyridine]-4-carbonitrile. CAS No. 2225123-30-6. Molecular formula: C30H29FN6O2. Mole weight: 524.60.
Gemopatrilat
Gemopatrilat, an azepan derivative, has been found to be an angiotensin receptor as well as vasopeptidase inhibitor that was once studied against hypertension and heart failure. Uses: Vasopeptidase inhibitors. Synonyms: Gemopatrilat; BMS 189921; BMS-189921; BMS189921; SCHEMBL1973289; {(6S)-2,2-dimethyl-7-oxo-6-[(3-phenyl-2-sulfanylpropanoyl)amino]azepan-1-yl}acetic acid; 2-[2,2-dimethyl-7-oxo-6-[(3-phenyl-2-sulfanylpropanoyl)amino]azepan-1-yl]acetic acid. Grade: 98%. CAS No. 160135-92-2. Molecular formula: C19H26N2O4S. Mole weight: 378.49.
Gemtuzumab
Gemtuzumab (brand name Mylotarg) is a monoclonal antibody used in the treatment of acute myeloid leukemia (AML). Gemtuzumab targets CD33, a protein found on the surface of myeloid cells, including leukemic cells in AML. By binding to CD33, gemtuzumab may induce antibody-dependent cellular cytotoxicity (ADCC), leading to destruction of CD33-positive leukemia cells. Gemtuzumab is indicated for the treatment of newly diagnosed CD33-positive AML in adults, as well as for relapsed or refractory CD33-positive AML in both adults and pediatric patients. Synonyms: Immunoglobulin G4, anti-(human CD33 antigen) (human-mouse monoclonal hP67.6 γ4-chain)), disulfide with human-mouse monoclonal hP67.6 κ-chain, dimer; hP67.6. CAS No. 2924764-21-4.
GenBank AX727681
GenBank AX727681, a promising drug target for the treatment of breast and ovarian cancer, exhibits a pivotal function in regulating cell proliferation and survival. Its potential therapeutic significance highlights the need for further investigation and exploration in the realm of targeted cancer therapy. Synonyms: methyl 2-(phenylamino)acetate hydrochloride; 78733-46-7; 515028-39-4; GenBank AX727681 (9CI); methyl 2-anilinoacetate; hydrochloride; SCHEMBL76327; phenylglycine methyl ester HCl; phenyl glycine methyl ester-hcl; AJHZGVMKIXHMNP-UHFFFAOYSA-N; AKOS008030912; AM82657; methyl2-(phenylamino)acetatehydrochloride; phenyl-glycine methyl ester hydrochloride; AS-57817; N-phenylglycine methyl ester hydrochloride; methyl (+/-)-phenylglycinate hydrochloride; methyl 2-phenylazanylethanoate hydrochloride; CS-0262026; FT-0688104; EN300-80938; 2-anilinoacetic acid methyl ester hydrochloride; A809027; Z1250132387. CAS No. 515028-39-4. Molecular formula: C9H12ClNO2. Mole weight: 201.65.
GenBank CX447129 (9CI)
pyridine-3-sulfonyl chloride is mainly used for preparing TAK-438 (vonoprazan fumarate), which is a novel orally active potassium-competitive acid blocker, developed as an antisecretory drug. Synonyms: 3-Pyridinesulfonyl chloride; m-Pyridinesulfonyl Chloride; chloro-3-pyridylsulfone. Grade: 95%. CAS No. 813222-82-1. Molecular formula: C5H4ClNO2S. Mole weight: 177.61.
Genistein
Genistein, a phytoestrogen found in soy products, is a highly specific inhibitor of protein tyrosine kinase (PTK) which blocks the mitogenic effect mediated by EGF on NIH-3T3 cells with IC50 of 12μM or by insulin with IC50 of 19 μM. Genistein is developed to be an antitumor agent. Genistein has antioxidant effect, it can be used in cosmetics material. It is a plant polyphenol that can inhibit tyrosinase, block melanin synthesis, reduce skin pigment intensity, absorb UV, prevent photoaging, reduce sun damage and age spot formation, and whiten and lighten spots. It also has the anti-glycation and antibacterial effect, can effectively improve skin tone and skin texture, prevent the generation of age spots, remove red bloodlines, and improve skin blood microcirculation. Uses: Antitumor agent. Synonyms: 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; Baichanin A; Bonistein; 4',5,7-Trihydroxyisoflavone; GeniVida; Genisteol; NSC 36586; Prunetol; Sophoricol; Differenol A. Grade: >98%. CAS No. 446-72-0. Molecular formula: C15H10O5. Mole weight: 270.24.
Gentamicin B1 Acetate Salt is the salt form of Gentamicin B1, which is a derivative of Gentamicin, an aminoglycoside antibiotic. Synonyms: Gentamycin B1 Acetate Salt; O-6-Amino-6,7-dideoxy-D-glycero-α-D-gluco-heptopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)]-2-deoxy-D-Streptamine Acetate Salt. Grade: 87%. Molecular formula: C20H40N4O10.xC2H4O2. Mole weight: 496.56 (free base).
Gentamicin C1a Deuterated Pentaacetate Salt
Gentamicin C1a Deuterated Pentaacetate Salt is the isotope labelled analog of Gentamicin C1a Pentaacetate Salt, and an antibacterial. Synonyms: O-3-Deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1-6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-α-D-erythro-hexopyranosyl-(1-4)]-2-deoxy-D-streptamine Pentaacetate Salt Deuterated; Gentamicin D Acetate Deuterated; Gentamycin C1a Acetate Deuterated; Gentamicin C3 Acetate Deuterated. Molecular formula: C19H39N5O7 C10H20O10. Mole weight: 449.54.
Gentamicin C1 Deuterated Pentaacetate Salt is the isotope labelled analog of Gentamicin C1 Pentaacetate Salt and an antibacterial. Synonyms: O-2-Amino-2,3,4,6,7-pentadeoxy-6-(methylamino)-α-D-ribo-heptopyranosyl-(14)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(16)]-2-deoxy-D-streptamine Pentaacetate Salt Deuterated. Grade: 90%. CAS No. 287730-69-2. Molecular formula: C31H63N5O17. Mole weight: 777.86.
Gentamicin C1 Pentaacetate Salt
Gentamicin C1 Pentaacetate Salt is an efficacious antibiotic compound, demonstrating remarkable potential in studying an array of diverse bacterial infections. Categorized under the class of aminoglycoside antibiotics, this compound effectively hinders the protein synthesis process within microbial organisms. Uses: Anti-bacterial agents; protein synthesis inhibitors. Synonyms: O-2-Amino-2,3,4,6,7-pentadeoxy-6-(methylamino)-α-D-ribo-heptopyranosyl-(14)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(16)]-2-deoxy-D-streptamine Pentaacetate Salt. Grade: 95%. Molecular formula: C31H63N5O17. Mole weight: 777.86.
Gentamicin C2 Pentaacetate Salt (Mixture of C2 and C2a)
Antibacterial. A mixture of Gentamicin C2 and Gentamycin C2a. Synonyms: O-3-Deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)-O-[(6ξ)-2,6-diamino-2,3,4,6,7-pentadeoxy-α-D-erythro-heptopyranosyl-(1→4)]-2-deoxy-D-streptamine Pentaacetate Salt; Gentamicin C2/C2a Mixture Pentaacetate Salt. Grade: 95%. Molecular formula: C30H61N5O17. Mole weight: 763.83.
Gentamycin Impurity E
Gentamycin Impurity E is an important component of several aminocyclitol antibiotics. Synonyms: 2-Deoxystreptamine dihydrobromide; 2-DOS ยท 2HBr; 4t,6t-Diamino-cyclohexan-1r,2t,3c-triol; 2-Deoxy-1,3-myo-inosadiamine. Grade: > 95%. CAS No. 84107-26-6. Molecular formula: C6H16N2O3Br2. Mole weight: 324.01.
Gentamycin Sulfate EP Impurity C
Gentamycin Sulfate EP Impurity C. Synonyms: 4-O-(6-Amino-6,7-dideoxy-α-D-glycero-D-gluco-heptopyranosyl)-6-O-(4-methyl-3-methylamino-3-deoxy-β-L-arabinopyranosyl)-2-deoxy-D-streptamine; ; Gentamycin B1; D-Streptamine, o-6-amino-6,7-dideoxy-D-glycero-alpha-D-gluco-heptopyranosyl-(1-4)-o-(3-deoxy-4-C-me. Grade: > 95%. CAS No. 36889-16-4. Molecular formula: C20H40N4O10. Mole weight: 496.56.
Gentamycin sulfate EP impurity D
Gentamycin sulfate EP impurity D. Grade: > 95%. Molecular formula: C19H39N5O9. Mole weight: 481.55.
Gentianose
Gentianose is a remarkable disaccharide derived from the gentian root, exhibiting its innate aptitude to suppress inflammatory processes. By integrating Gentianose into pharmaceutical compositions, manifold ailments including diabetes, liver maladies and gastrointestinal anomalies can be study. Synonyms: b-D-Glc-(1->6)-a-D-Glc-(1<->2)-b-D-Fru; b-D-fructofuranosyl 6-O-b-D-glucopyranosyl-a-D-glucopyranoside; β-D-Fructofuranosyl O-β-D-glucopyranosyl-(1→6)-α-D-glucopyranoside. CAS No. 25954-44-3. Molecular formula: C18H32O16. Mole weight: 504.45.
Gentiobiulose
Gentiobiulose is a remarkable compound, applied in the research of conquering resilient bacterial infections. Its antibacterial potency transpires through the inhibition of diverse bacterial growth, encompassing the notorious strains such as Staphylococcus aureus and Escherichia coli. Synonyms: 6-O-(b-D-Glucopyranosyl)-D-fructose. CAS No. 132436-90-9. Molecular formula: C12H22O11. Mole weight: 342.30.
Gentioheptaose
Gentioheptaose is an intricately structured carbohydrate, finding indispensable utility in the research of bacterial and viral infections. CAS No. 144448-00-0. Molecular formula: C42H72O36. Mole weight: 1153.00.
Gentiohexaose
Gentiohexaose is an extensively employed carbohydrate compound, used for studying diverse ailments such as diabetes and cancer. CAS No. 37698-89-8. Molecular formula: C36H62O31. Mole weight: 990.86.
Gentiopentaose
Gentiopentaose is a type of oligosaccharide used in the biomedical industry for its potential role in treating cancer and improving the immune system. Studies have shown that gentiopentaose has anti-tumor effects by inhibiting cancer cell growth and inducing apoptosis. It also has immunomodulatory properties by activating T cells and enhancing natural killer cell function. Gentipentaose shows great promise as a therapeutic agent for cancer and immune-related diseases. Synonyms: O-β-D-Glucopyranosyl-(1→6)-O-β-D-glucopyranosyl-(1→6)-O-β-D-glucopyranosyl-(1→6)-O-β-D-glucopyranosyl-(1→6)-D-glucose; Glc(b1-6)Glc(b1-6)Glc(b1-6)Glc(b1-6)aldehydo-Glc. CAS No. 37796-54-6. Molecular formula: C30H52O26. Mole weight: 828.72.
Gentiotetraose
Gentiotetraose is a distinctive biomedical compound with profound resemblance to endogenous glycoconjugates, thus used for studying autoimmune disorders and chronic inflammatory ailments. Synonyms: O-b-D-Glucopyranosyl-(1→6)-O-b-D-glucopyranosyl-(1→6)-O-b-D-glucopyranosyl-(1→6)-D-glucose. CAS No. 37796-39-7. Molecular formula: C24H42O21. Mole weight: 666.58.
Gentiotriose
b-D-Gentiotriose is an anti-inflammatory and antioxidant compound, unveiling its extraordinary prowess in research of the pressing ailments of diabetes and cardiovascular disorders. E. Synonyms: b-D-Gentiotriose; O-β-D-Glucopyranosyl-(1→6)-O-β-D-glucopyranosyl-(1→6)-D-glucose; D-Gentiotriose; Glc(b1-6)Glc(b1-6)aldehydo-Glc; (2R,3S,4R,5R)-2,3,4,5-Tetrahydroxy-6-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)hexanal. CAS No. 32590-17-3. Molecular formula: C18H32O16. Mole weight: 504.44.
Genz-123346
Genz-123346 is an inhibitor of GL1 synthase that blocks the conversion of ceramide to GL1. It does not inhibit α-glucosidase or glucocerebrosidase. It lowered glucose and A1C levels and improved glucose tolerance in the Zucker diabetic fatty rat. Synonyms: Genz-123346; Genz123346; Genz 123346. Grade: >98%. CAS No. 943344-58-9. Molecular formula: C52H82N4O14. Mole weight: 987.23.
Genz-123346 Free base
Genz-123346 is a glucosylceramide synthase inhibitor with potential anticancer activity. Exposure of cells to Genz-123346 and to other GCS inhibitors at non-toxic concentrations can enhance the killing of tumor cells by cytotoxic anti-cancer agents. Genz-123346 and a few other GCS inhibitors are substrates for multi-drug resistance efflux pumps such as P-gp (ABCB1, gP-170). In cell lines selected to over-express P-gp or which endogenously express P-gp, chemosensitization by Genz-123346 was primarily due to the effects on P-gp function. Synonyms: Genz-123346; Genz123346; Genz 123346. CAS No. 491833-30-8. Molecular formula: C24H38N2O4. Mole weight: 418.57.
GENZ-644282
Genz-644282 is a non-camptothecin inhibitor of topoisomerase I with potential antineoplastic activity. Topoisomerase I inhibitor Genz-644282 binds to and inhibits the enzyme topoisomerase I, which may result in the inhibition of repair of single-strand DNA breaks, DNA replication, and tumor cell growth in susceptible tumor cell populations. Synonyms: GENZ-644282; GENZ644282; GENZ 644282. CAS No. 529488-28-6. Molecular formula: C24H22F3N3O7. Mole weight: 521.44.
GENZ-882706
GENZ-882706 is a potent colony stimulating factor-1 receptor (CSF-1R) inhibitor. (Extracted from patent WO 2017015267A1). Synonyms: (S)-4-(3-((2-(6-methoxypyridin-3-yl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methyl)-3H-imidazo[4,5-b]pyridin-6-yl)-2-methylbut-3-yn-2-amine; 4-(3-{[(2S)-2-(6-Methoxy-3-pyridinyl)-2,3-dihydro-1,4-benzodioxin-6-yl]methyl}-3H-imidazo[4,5-b]pyridin-6-yl)-2-methyl-3-butyn-2-amine; 3-Butyn-2-amine, 4-[3-[[(2S)-2,3-dihydro-2-(6-methoxy-3-pyridinyl)-1,4-benzodioxin-6-yl]methyl]-3H-imidazo[4,5-b]pyridin-6-yl]-2-methyl-. Grade: ≥95%. CAS No. 2070864-35-4. Molecular formula: C26H25N5O3. Mole weight: 455.51.
GENZ-882706 (Raceme)
GENZ-882706 (Raceme) is the racemate of GENZ-882706, which is a potent colony stimulating factor-1 receptor (CSF-1R) inhibitor. It is a ligand used for the synthesis of PROTACs. Synonyms: GENZ-882706 racemate; 3-Butyn-2-amine, 4-[3-[[2,3-dihydro-2-(6-methoxy-3-pyridinyl)-1,4-benzodioxin-6-yl]methyl]-3H-imidazo[4,5-b]pyridin-6-yl]-2-methyl-; 4-(3-{[2-(6-Methoxy-3-pyridinyl)-2,3-dihydro-1,4-benzodioxin-6-yl]methyl}-3H-imidazo[4,5-b]pyridin-6-yl)-2-methyl-3-butyn-2-amine. Grade: ≥95%. CAS No. 2070861-46-8. Molecular formula: C26H25N5O3. Mole weight: 455.51.
Gepotidacin
Gepotidacin is a potent Type II DNA topoisomerase inhibitor. It is a novel antibacterial drug candidate. It is used for the treatment of gram positive bacterial infection of skin and skin structure. It is also used for the treatment of gonorrhea. It was developed by GlaxoSmithKline R & D and in clinic phase 2 trials. Uses: Gepotidacin is used for the treatment of gram positive bacterial infection of skin and skin structure. it is also used for the treatment of gonorrhea. Synonyms: GSK-2140944; GSK2140944; GSK 2140944; GSK-2140944E; GSK2140944E; GSK 2140944E; (2R)-2-[(4-{[(3,4-dihydro-2H-pyrano[2,3-c]pyridin- 6-yl)methyl]amino}piperidin-1-yl)methyl]-1,2-dihydro- 3H,8H-2a,5,8a-triazaacenaphthylene-3,8-dione. Grade: >98%. CAS No. 1075236-89-3. Molecular formula: C24H28N6O3. Mole weight: 448.53.
Gepotidacin S enantiomer
Gepotidacin S enantiomer is an S enantionmer of gepotidacin which is a potent Type II DNA topoisomerase inhibitor and appears as a novel antibacterial drug candidate. Synonyms: Gepotidacin (S enantiomer). CAS No. 2319789-82-5. Molecular formula: C24H28N6O3. Mole weight: 448.52.
Geranylated 5-carboxymethylaminomethyl-2-thiouridine, a modified nucleotide resident in transfer RNA, performs a critical role in protein synthesis with remarkable potential for therapeutic intervention in melanoma and breast cancer. Inhibiting tumor growth and upholding cancer cell death, geranylated 5-carboxymethylaminomethyl-2-thiouridine's distinctive structural attributes permit selective targeting of cancerous cells while sparing the healthy ones, thus gaining significant attention as a future cancer treatment yet to be unleashed. Molecular formula: C22H33N3O7S. Mole weight: 483.32.
geranylated 5-methylaminomethyl-2-thiouridine
Geranylated 5-methylaminomethyl-2-thiouridine is a modified nucleoside that has shown antiviral activity against HIV-1 and HCV. It has potential therapeutic applications in the treatment of viral infections. Research show that geranylated 5-methylaminomethyl-2-thiouridine afforded selective inhibition against HIV-1 Vif translation and HIV-1 replication. Molecular formula: C21H33N3O5S. Mole weight: 439.32.
Geranyl b-D-glucoside
Geranyl b-D-glucoside, a naturally occurring compound abundantly distributed across diverse botanical species, has garnered significant attention due to its remarkable bioactive attributes. The biomedical realm has extensively explored the therapeutic prospects of this compound, unveiling its potential in combating an array of ailments, ranging from cancer and inflammation to neurodegenerative disorders. The multifaceted pharmacological characteristics exhibited by Geranyl b-D-glucoside render it an exceedingly promising target that merits extensive scrutiny within the realm of pharmaceutical advancements. CAS No. 22850-13-1. Molecular formula: C16H28O6. Mole weight: 316.39.
Geranylgeranylacetone
Geranylgeranylacetone is commonly utilized to protect the gastric mucosa in peptic ulcer disease can induce expression of HSP70, HSPB8, and HSPB1. Uses: An anti-ulcerative. Synonyms: Teprenone; 6,10,14,18-Tetramethyl-5,9,13,17-nonadecatetraen-2-one. Grade: ≥95%. CAS No. 6809-52-5. Molecular formula: C23H38O. Mole weight: 330.55.
Geranyl Linalool O-β-D-Glucoside
Geranyl Linalool O-β-D-Glucoside is an analog of Geranyl Linalool, an aliphatic genaryl derivative. Geranyl Linalool unlike other genaryl derivatives showed poor inhibitory activity against carotenoid synthesis in Synechococcus. Geranyl Linalool was identified as a testosterone-dependent volatile compound in the preputial gland of rat Rattus norvegicus. Synonyms: (2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-(((6E,10E)-3,7,11,15-tetramethylhexadeca-1,6,10,14-tetraen-3-yl)oxy)tetrahydro-2H-pyran-3,4,5-triol. Molecular formula: C26H44O6. Mole weight: 452.62.
Germaben II
Germaben II is used to inhibit microbial, yeast and mould growth in cosmetics and other personal products. It contains propylene glycol, propylparaben, methylparaben, and diazolidinyl urea. It is used primarily by small businesses or home hobbyists who ma. Grade: > 95%. CAS No. 84517-95-3. Molecular formula: C29H42O15N4. Mole weight: 686.68.
Germacrone
Germacrone is isolated from the rhizoma of Curcuma wenyujin. It has anti-tumor activity. Germacrone is a natural antiviral agent against porcine parvovirus (PPV). Uses: Antibacterial; antifungal. Synonyms: Germacron; 3,7-Cyclodecadien-1-one, 3,7-dimethyl-10-(1-methylethylidene)-, (E,E)-; (E,E)-Germacrone. Grade: 98%. CAS No. 6902-91-6. Molecular formula: C15H22O. Mole weight: 218.33.
Germinone A
Germinone A is a potent HTL/KAI2 agonist that stimulates Arabidopsis seed germination activity and has antitumor activity against a variety of carcinomas types. Synonyms: 2(5H)-Furanone, 3-methyl-5-[(3-nitro[1,1'-biphenyl]-4-yl)oxy]-; 3-Methyl-5-((3-nitro-[1,1'-biphenyl]-4-yl)oxy)furan-2(5H)-one; 3-Methyl-5-[(3-nitro[1,1'-biphenyl]-4-yl)oxy]-2(5H)-furanone. Grade: ≥95%. CAS No. 2375197-79-6. Molecular formula: C17H13NO5. Mole weight: 311.29.
Gestodene
Gestodene is a progestogen hormonal contraceptive.Gestodene is androgenically neutral, meaning that contraceptive pills containing gestodene do not exhibit the androgenic side effects often associated with second-generation contraceptive pills, such as those containing levonorgestrel. Synonyms: 18,19-Dinorpregna-4,15-dien-20-yn-3-one, 13-ethyl-17-hydroxy-, (17α)-; (17α)-13-Ethyl-17-hydroxy-18,19-dinorpregna-4,15-dien-20-yn-3-one; Gestinol; SHB 331; WL 70; (8R,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,9,10,11,12,13,14,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one. Grade: >98%. CAS No. 60282-87-3. Molecular formula: C21H26O2. Mole weight: 310.43.
Gestodene 17-O-β-D-glucuronide
Gestodene 17-O-β-D-glucuronide is a metabolite of Gestodene, which is a potent progestogen used primarily in combined oral contraceptive pills. Synonyms: (17α)-3-Oxo-13-ethyl-18,19-dinorpregna-4,15-dien-20-yn-17-yl β-D-glucopyranosiduronic acid; (2S,3S,4S,5R,6S)-6-{(1S,2R,10R,11S,14R,15S)-15-Ethyl-14-ethynyl-5-oxotetracyclo[8.7.0.02,7.011,15]heptadeca-6,12-dien-14-yloxy}-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid; (17α)-13-Ethyl-17-hydroxy-18,19-dinorpregna-4,15-dien-20-yn-3-one β-D-glucopyranosiduronic acid; Gestinol β-D-glucopyranosiduronic acid; Gestodene glucuronide. Grade: ≥95%. Molecular formula: C27H34O8. Mole weight: 486.57.
Gestodene-3-Methyldienol Ether
An impurity of Gestodene, which is a synthetic progesterone used primarily in female contraceptives and menopausal hormone therapy. Synonyms: Gestodene-3-methoxy Dienol Ether; (8R,9S,10R,13S,14S,17R)-13-Ethyl-17-ethynyl-3-methoxy-2,7,8,9,10,11,12,13,14,17-decahydro-1H-cyclopenta[a]phenanthren-17-ol; 18,19-Dinorpregna-3,5,15-trien-20-yn-17-ol, 13-ethyl-3-methoxy-, (17α)-; (17α)-13-Ethyl-3-methoxy-18,19-dinorpregna-3,5,15-trien-20-yn-17-ol; 3-Enol Gestodene. Grade: ≥95%. CAS No. 104934-01-2. Molecular formula: C22H28O2. Mole weight: 324.47.