BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Ibuprofen Impurity A | Cas No. 66622-47-7. |  |
| Ibuprofen Impurity K | Cas No. 43153-07-7. | |
| Ibuprofen Impurity L | Cas No. 53949-53-4. | |
| Ibuprofen lysine | Ibuprofen lysine is a non-selective COX inhibitor that can be used as an anti-inflammatory drug. Synonyms: Arflamin; NeoProfen; Saren. Grades: >98%. CAS No. 57469-77-9. Molecular formula: C19H32N2O4. Mole weight: 352.47. | |
| ICA-069673 | ICA-069673 is an orally active, potent and selective KCNQ2/Q3 potassium channel activator (IC50= 0.69 μM) with 20-fold selectivity for KV7.2/KV7.3 over KV7.3/KV7.5 (EC50s = 14.3 μM). Synonyms: ICA 069673; ICA069673. CAS No. 582323-16-8. Molecular formula: C11H6ClF2N3O. Mole weight: 269.63. | |
| Icatibant Acetate | Icatibant acetate is a selective antagonist of bradykinin B2 receptors. Icatibant is a medication approved for the treatment of acute attacks of hereditary angioedema (HAE) in adults with C1-esterase-inhibitor deficiency. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: HOE 140 Acetate; HOE140 Acetate; HOE-140 Acetate; L-Arginine, D-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-(3R)-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-(2S,3aS,7aS)-octahydro-1H-indole-2-carbonyl-, acetate (1:x); H-D-Arg-Arg-Pro-Hyp-Gly-2Thi-Ser-D-Tic-Oic-Arg-OH.CH3CO2H; L-Arginine, D-arginyl-L-arginyl-L-prolyl-trans-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-D-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-L-(2α,3aβ,7aβ)-octahydro-1H-indole-2-carbonyl-, acetate (salt); Firazyr. Grades: ≥95%. CAS No. 138614-30-9. Molecular formula: C59H89N19O13S.xC2H4O2. Mole weight: 1304.52 (free base). | |
| ICEC-0942 | ICEC-0942 is a small-molecule cyclin-dependent kinase 7 (CDK7) inhibitor developed for cancer therapy. Preclinical study in Acute Myeloid Leukaemia (AML) models shows that ICEC-0942 effectively inhibits the proliferation of several AML cell lines and patient derived AML cells in vitro (IC50 = 0.15-2.6 μM). Uses: Anticancer drug. Synonyms: CT7001; CT 7001; CT-7001; ICEC0942; ICEC0 942; ICEC0-942. CAS No. 1805833-75-3. Molecular formula: C22H30N6O. Mole weight: 394.52. | |
| Icilin | Icilin is a synthetic CMR1/TRPM8 super agonist in CMR1-expressing HEK 293 cells (EC50 = 0.36 μM) more potently than menthol or low temperatures. Uses: Both heat sensitive (vr1) and cold-sensitive (cmr1 (rat); trpm8 (human)) receptors. Synonyms: AG 3-5; AG3-5; AG-3-5; AG 3-5 cpd; 3,4-Dihydro-3-(2-hydroxyphenyl)-6-(3-nitrophenyl)-(1H)-pyrimidin-2-one;3,6-dihydro-1-(2-hydroxyphenyl)-4-(3-nitrophenyl)-2(1H)-pyrimidinone. Grades: ≥98%. CAS No. 36945-98-9. Molecular formula: C16H13N3O4. Mole weight: 311.29. | |
| Iclaprim | Cas No. 192314-93-5. | |
| Icometasone | Cas No. 4647-20-5. | |
| Icomethasone 21-Acetate | Cas No. 24916-91-4. | |
| Icomethasone 21-Mesylate | Cas No. 352315-75-4. | |
| Icotinib | Icotinib Hydrochloride (BPI-2009H), or Icotinib, is a highly selective, first generation epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI). Synonyms: BPI-2009H. Grades: >98%. CAS No. 610798-31-7. Molecular formula: C22H21N3O4. Mole weight: 391.42. | |
| Idasanutlin | Idasanutlin; also known as RG7388 and RO5503781, is a highly potent and selective MDM2 antagonist with potential anticancer activity. RG7388 binds to MDM2 blocking the interaction between the MDM2 protein and the transcriptional activation domain of the tumor suppressor protein p53. By preventing the MDM2-p53 interaction, p53 is not enzymatically degraded and the transcriptional activity of p53 is restored. This may lead to p53-mediated induction of tumor cell apoptosis. MDM2, a zinc finger nuclear phosphoprotein and negative regulator of the p53 pathway, is often overexpressed in cancer cells and has been implicated in cancer cell proliferation and survival. Uses: For research used only. Synonyms: RG7388; RG 7388; RG-7388; RO5503781; RO-5503781; RO 5503781. Grades: >98%. CAS No. 1229705-06-9. Molecular formula: C31H29Cl2F2N3O4. Mole weight: 616.487. | |
| Idazoxan hydrochloride | Idazoxan hydrochloride is the hydrochloride salt of idazoxan, which is an I2 imidazoline receptor agonist, I1 imidazoline receptor antagonist, as well as an alpha2-adrenoceptor antagonist. It is selective for α2- over α1-receptors. It is useful for the treatment of parkinsonian and schizophrenia. Synonyms: 1H-Imidazole, 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-, hydrochloride (1:1); 1H-Imidazole, 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-, monohydrochloride; (±)-Idazoxan monohydrochloride; 2-(2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole hydrochloride; RX 781094; RX 781094A. Grades: ≥98%. CAS No. 79944-56-2. Molecular formula: C11H13ClN2O2. Mole weight: 240.69. | |
| Idelalisib | Idelalisib is a kinase inhibitor. In combination with rituximab, it was used for the treatment of relapsed or refractory chronic lymphocytic leukemia (CLL). Uses: The treatment of chronic lymphocytic leukemia (cll). Synonyms: Idelalisib; CAL101; CAL 101; CAL-101; GS1101; GS 1101; GS-1101, Idelalisib. Grades: > 95%. CAS No. 870281-82-6. Molecular formula: C22H18FN7O. Mole weight: 415.432. | |
| IFN alpha-IFNAR-IN-1 hydrochloride | IFN alpha-IFNAR-IN-1 hydrochloride is a nonpeptidic, low-molecular-weight inhibitor. It inhibits modified Vaccinia virus ankara (MVA)-induced IFN-α responses in murine bone-marrow-derived, Flt3-L-differentiated pDC cultures (BM-pDCs) (IC50=2-8 μM). Synonyms: IFN-alpha/IFNAR-IN-1 hydrochloride. CAS No. 2070014-98-9. Molecular formula: C18H18ClNS. Mole weight: 315.86. | |
| Iguratimod | Iguratimod is a selective inhibitor of cyclo-oxygenase-2 (COX-2), and inhibits the production of interleukin-1 (IL-1), IL-6, IL-8 and tumour necrosis factor. Uses: Anti-inflammation agent. Synonyms: T 614; T-614; T614; N-(7-(Methylsulfonamido)-4-oxo-6-phenoxy-4H-chromen-3-yl)formamide; Careram; Kolbet; UNII-4IHY34Y2NV. Grades: 0.98. CAS No. 123663-49-0. Molecular formula: C17H14N2O6S. Mole weight: 374.367. | |
| IK-930 | IK930, a novel TEAD inhibitor, sensitizes KRAS and EGFR mutant tumors to oncogene targeted therapy. CAS No. 2563892-44-2. Molecular formula: C19H19F3N4O2S. Mole weight: 424.44. | |
| Ilomastat | Ilomastat is a broad-spectrum matrix metalloproteinase inhibitor, displaying potential anticancer activity. Ilomastat is a member of the hydroxamic acid class of reversible metallopeptidase inhibitors. The anionic state of the hydroxamic acid group forms a bidentate complex with the active site zinc. Ilomastat inhibits enzymes including thermolysin, peptide deformylase, and anthrax lethal factor endopeptidase (LF) produced by the bacterium Bacillus anthracis. Synonyms: GM6001; GM-6001; GM 6001; Ilomastat; galardin; (2R)-N'-hydroxy-N-[(2S)-3-(1H-indol-3-yl)-1-(methylamino)-1-oxopropan-2-yl]-2-(2-methylpropyl)butanedia. Grades: 98%. CAS No. 142880-36-2. Molecular formula: C20H28N4O4. Mole weight: 388.468. | |
| Iloprost | Iloprost is a drug used to treat pulmonary arterial hypertension (PAH), scleroderma, Raynaud's phenomenon and other diseases in which the blood vessels are constricted and blood can't flow to the tissues. Synonyms: Pentanoic acid, 5-[(3aS,4R,5R,6aS)-hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyl-1-octen-6-yn-1-yl]-2(1H)-pentalenylidene]-, (5E)-; (5E)-5-[(3aS,4R,5R,6aS)-Hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyl-1-octen-6-yn-1-yl]-2(1H)-pentalenylidene]pentanoic acid; Pentanoic acid, 5-[(3aS,4R,5R,6aS)-hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyl-1-octen-6-ynyl]-2(1H)-pentalenylidene]-, (5E)-; (1S,2R,3R,5S)-7-[(E)-4-Carboxybutylidene]-2-[(3S,1E)-3-hydroxy-4-methyl-6-octyn-1-enyl]-bicyclo[3.3.0]octane; Ciloprost; Endoprost; Ilomedin; ZK 36374. Grades: 98%. CAS No. 78919-13-8. Molecular formula: C22H32O4. Mole weight: 360.49. | |
| Imatinib EP Impurity D | An impurity of Imatinib, a tyrosine kinase inhibitor used as a chemotherapy drug for the treatment of leukemia and other kinds of cancer. Synonyms: Des(methylpiperazinyl) Imatinib Dimer Piperazinium Chloride; 1-Methyl-1, 4-bis[4-[ (4-methyl-3-[[4- (pyridin-3-yl) pyrimidin-2-yl]amino]phenyl) carbamoyl]benzyl]piperazin-1-ium chloride. Grades: > 95%. CAS No. 1821122-73-9. Molecular formula: C53H51ClN12O2. Mole weight: 923.50. | |
| Imatinib EP Impurity J | An impurity of Imatinib, a tyrosine kinase receptor inhibitor used for cancer therapy. Synonyms: Imatinib (Piperidine)-N-oxide; 4-[(4-Methyl-4-oxido-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide; CGP 71422; CGP71422; CGP-71422. Grades: > 95%. CAS No. 571186-91-9. Molecular formula: C29H31N7O2. Mole weight: 509.62. | |
| Imatinib Guanidine Impurity | An impurity of Imatinib, a tyrosine kinase receptor inhibitor used for cancer therapy. Synonyms: N-(3-Guanidino-4-methylphenyl)-4-(methylpiperazine-1-yl-methyl)benzamide; N-[3-[(Aminoiminomethyl)amino]-4-methylphenyl]-4-[(4-methyl-1-piperazinyl)methyl]benzamide; N- [2-Methyl-5- [ [4- [ (4-methylpiperazin-1-yl) methyl] benzoyl] amino] phenyl] guanidine. Grades: > 95%. CAS No. 581076-65-5. Molecular formula: C21H28N6O. Mole weight: 380.50. | |
| Imatinib Impurity C | an impurity of Imatinib (Gleevec). Synonyms: Imatinib (Piperidine)-1-oxide; 4-[(4-Methyl-1-oxido-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide. Grades: > 95%. CAS No. 938082-57-6. Molecular formula: C29H31N7O2. Mole weight: 509.62. | |
| Imatinib Impurity E | an impurity of Imatinib (Gleevec). Synonyms: Des(methylpiperazinyl-N-methyl) Imatinib Dimer Impurity; 4,4'-(piperazine-1,4-diylbis(methylene))bis(N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide). Grades: > 95%. CAS No. 1365802-18-1. Molecular formula: C52H48N12O2. Mole weight: 873.04. | |
| Imatinib Impurity M | An impurity of Imatinib, a tyrosine kinase inhibitor used as a chemotherapy drug for the treatment of leukemia and other kinds of cancer. Synonyms: 1,4-Bis(4-carboxybenzyl)-1-methylpiperazin-1-ium (Imatinib Impurity); 1,4-BIS(4-CARBOXYBENZYL)-1-METHYLPIPERAZIN-1-IUM; Imatinib Impurity M; SCHEMBL14646970; CS-0255288; F83280. CAS No. 1407229-73-5. Molecular formula: C21H25N2O4+. Mole weight: 369.44. | |
| Imatinib methyl dimer Impurity | An impurity of Imatinib, a tyrosine kinase inhibitor used as a chemotherapy drug for the treatment of leukemia and other kinds of cancer. Synonyms: 1-Methyl-1, 4-bis [ [4- [ [ [4-methyl-3- [ [4- (3-pyridinyl) -2-pyrimidinyl] amino] phenyl] amino] carbonyl] phenyl] methyl] piperazinium iodide (1:1). Grades: ≥95%. CAS No. 1821122-74-0. Molecular formula: C53H51N12O2I. Mole weight: 1014.96. | |
| Imatinib Related Substance B | An impurity of Imatinib, a tyrosine kinase receptor inhibitor used for cancer therapy. Synonyms: Imatinib (Piperidine)-N,N-dioxide; 4-[(4-Methyl-1,4-dioxido-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide. Grades: > 95%. CAS No. 571186-93-1. Molecular formula: C29H31N7O3. Mole weight: 525.62. | |
| IMD 0354 | IMD-0354 is an IKKβ inhibitor and blocks IκBα phosphorylation in NF-κβ pathway. Synonyms: IMD-0354; IMD 0354; IMD0354. Grades: >98%. CAS No. 978-62-1. Molecular formula: C15H8ClF6NO2. Mole weight: 383.674. | |
| Imeglimin hydrochloride | Imeglimin hydrochloride is the first in a new tetrahydrotriazine-containing class of oral antidiabetic agents, the glimins. It has been shown to act on the liver, muscle and pancreatic β-cells to uniquely target the key defects of type 2 diabetes. Synonyms: EMD 387008 hydrochloride; EMD387008 hydrochloride; EMD-387008 hydrochloride. Grades: >98%. CAS No. 775351-61-6. Molecular formula: C6H14ClN5. Mole weight: 191.7. | |
| Imidapril HCl | Imidapril HCl is an ACE inhibitor used as an antihypertensive drug and for the treatment of chronic heart failure. Grades: >98%. CAS No. 89396-94-1. Molecular formula: C20H27N3O6·HCl. Mole weight: 441.91. | |
| Iminostilbene-10,11-dihydrodiol | Iminostilbene-10,11-dihydrodiol is a metabolite of Carbamazepine, which is used in treatment of pain associated with trigeminal neuralgia. Synonyms: cis-10,11-Dihydro-5H-Dibenz[b,f]azepine-10,11-diol; 5H-Dibenz[b,f]azepine-10,11-diol, 10,11-dihydro-, cis-; (10R,11S)-10,11-Dihydro-5H-dibenzo[b,f]azepine-10,11-diol. Grades: ≥95%. CAS No. 56211-73-5. Molecular formula: C14H13NO2. Mole weight: 227.26. | |
| Imiquimod Related Compound B | A pharmacologically active compound related to Imiquimod, a toll-like receptor 7 agonist used as an immune response modifier. Synonyms: Desamino Imiquimod N-Oxide; 1-(2-Methylpropyl)-1H-imidazo[4,5-c]quinoline 5-Oxide; 1-Isobutyl-1H-imidazo[4,5-c]quinoline N-Oxide; USP Imiquimod Related Compound B. Grades: > 95%. CAS No. 99010-63-6. Molecular formula: C14H15N3O. Mole weight: 241.30. | |
| Imisopasem manganese | Imisopasem manganese is a manganese-based non-peptidyl mimetic of the human mitochondrial manganese superoxide dismutase (MnSOD), with potential antioxidant and chemo/radioprotective activities. Upon administration, imisopasem manganese mimics the activity of MnSOD and scavenges reactive oxygen species (ROS), such as superoxide anion, which prevents oxygen free radical damage to macromolecules such as DNA. Synonyms: M40403; M 40403; M 40403; CG4419; CG 4419; CG-4419; SC-72325; SC72325; SC 72325. Grades: >98%. CAS No. 218791-21-0. Molecular formula: C21H35Cl2MnN5. Mole weight: 483.39. | |
| IMR-1A | IMR-1A is a metabolite of IMR-1, and exhibits similar properties as IMR-1. IMR-1A inhibits Notch target gene transcription via disrupting recruitment of Mastermind 1 to the Notch transcriptional activation complex on chromatin, thereby suppressing tumor growth. Synonyms: IMR-1A; IMR 1A; IMR1A; Inhibitor of Mastermind Recruitment-1 Acid; 2-[2-methoxy-4-[(E)-(4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]phenoxy]acetic acid. CAS No. 331862-41-0. Molecular formula: C13H11NO5S2. Mole weight: 325.353. | |
| Indacaterol Impurity 1 | Synonyms: R-5-[2-(5,6-Diethyl-indan-2-ylamino)-1-hydroxy-ethyl]-8-hydroxy-3,4-dihydro-1H-quinolin-2-one. Grades: > 95%. CAS No. 1403389-05-8. Molecular formula: C24H30N2O3. Mole weight: 394.52. | |
| Indacaterol Impurity 2 | Synonyms: R-5-[2-(5-Ethyl-indan-2-ylamino)-1-hydroxy-ethyl]-8-hydroxy-3,4-dihydro-1H-quinolin-2-one. Grades: > 95%. CAS No. 1026461-20-0. Molecular formula: C22H24N2O3. Mole weight: 364.45. | |
| Indacaterol Impurity 3 | Synonyms: 5-[2-(5,6-Diethyl-indan-2-ylamino)-1-ethoxy-ethyl]-8-hydroxy-3,4-dihydro-1H-quinolin-2-one. Grades: > 95%. Molecular formula: C26H32N2O3. Mole weight: 420.56. | |
| Indacaterol Maleate | Indacaterol is an ultra-long-acting β-adrenoceptor agonist with pKi of 7.36. Synonyms: 5-[(1R)-2-[(5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-hydroxy-2(1H)-quinolinone Maleic Acid; QAB 149 Maleic Acid; Onbrez. Grades: >98%. CAS No. 753498-25-8. Molecular formula: C24H28N2O3.C4H4O4. Mole weight: 508.56. | |
| Indisulam | Indisulam is a carbonic anhydrase inibitor. It is a molecular glue that degrades mRNA splicing factor RBM39. Uses: Antineoplastic agents. Synonyms: E7070; E 7070; E-7070; ER35744; ER 35744; ER-35744; D04522; Indisulam. Grades: ≥98% (HPLC). CAS No. 165668-41-7. Molecular formula: C14H12ClN3O4S2. Mole weight: 385.84. | |
| Indolicidin | Indolicidin is the smallest of the naturally known occurring linear antimicrobial peptides, containing the highest percentage of tryptophan of any known protein, and consists of only six different amino acids. Indolicidin has been shown to be a fairly potent antimicrobial peptide with activity against a variety of microorganisms, fungi, and protozoa. Uses: Anti-infective agents. Synonyms: cationic antimicrobial peptide; H-Ile-Leu-Pro-Trp-Lys-Trp-Pro-Trp-Trp-Pro-Trp-Arg-Arg-NH2; L-isoleucyl-L-leucyl-L-prolyl-L-tryptophyl-L-lysyl-L-tryptophyl-L-prolyl-L-tryptophyl-L-tryptophyl-L-prolyl-L-tryptophyl-L-arginyl-L-argininamide. Grades: >98%. CAS No. 140896-21-5. Molecular formula: C100H132N26O13. Mole weight: 1906.28. | |
| Inecalcitol | Inecalcitol is an anologue of calcitriol. It is a VDR agonist with antineoplastic activity. Synonyms: TX-522; 19-Nor-14-epi-23-yne-1,25 dihydroxyvitamin D3. Grades: 95%. CAS No. 163217-09-2. Molecular formula: C26H40O3. Mole weight: 400.59. | |
| Ingenol | Ingenol, the analogue of Ingenol 3-Angelate found in the seeds of Euphorbia lathyris L, is an extremely weak PKC (protein kinase C) activator ( Ki=30μM, ED50=27μM, in vitro). Ingenol has anti-tumor activity when used topically for the treatment of actin. Uses: Anticancer. Synonyms: 1A,2,5,5A,6,9,10,10A OCTAHYDRO-5,5A,6-TRIHYDROXY4(HYDROXYMETHYL)1,1,7,9-TETRAMETHYL1H-2,8 AMETHANOCYCLOPENTA [A]CYCLOPROPA [E]CYCLODECEN-11 ONE;1 ALPHA,2,5,5 ALPHA,6,9,10,10 ALPHA-OCTAHYDRO-5,5 ALPHA,6-TRIHYDROXY-4-HYDROXYMETHYL-1,1,7,9-RETRAMETHYL-1H-2,8 A. Grades: >98%. CAS No. 30220-46-3. Molecular formula: C20H28O5. Mole weight: 348.44. | |
| Ingenol-5,20-acetonide | Ingenol-5,20-acetonide is extracted from the seeds of Euphorbia lathyris L. It is an analogue of Ingenol 3-Angelate. It is used as an intermediate for synthesis of ingenoids. It could improve stability compared to ingenol. Uses: Ingenol-5,20-acetonide is used as an intermediate for synthesis of ingenoids. it could improve stability compared to ingenol. Synonyms: (6R)-6, 6aβ, 7aβ, 8, 9, 12, 12a, 12bβ-Octahydro-12α, 12aα-dihydroxy-2, 2, 7, 7, 9β, 11-hexamethyl-7H-6β, 9aβ-methano-4H-cyclopenta[9, 10]cyclopropa[5, 6]cyclodeca[1, 2-d]-1, 3-dioxin-13-one. Grades: >98%. CAS No. 77573-43-4. Molecular formula: C23H32O5. Mole weight: 388.50. | |
| INH1 | INH1 is a cell-permeable Hec1 inhibitor, which specifically disrupts the Hec1/Nek2 interaction. Synonyms: IBT 13131; INH1; IBT13131; INH 1; IBT-13131; INH-1. Grades: >98%. CAS No. 313553-47-8. Molecular formula: C18H16N2OS. Mole weight: 308.40. | |
| Iopromide | Iopromide is a contrast medium produced by Bayer Healthcare. It is a low osmolar, non-ionic contrast agent for intravascular use. It can be used in radiographic studies including intravenous urograms, brain computer tomography and CT pulmonary angiograms. Uses: Contrast medium. Synonyms: N,N'-Bis(2,3-Dihydroxypropyl)-2,4,6-triiodo-5-[(methoxyacetyl)amino]-N-methyl-1,3-benzenedicarboxamide; Iopromidum; SHL 414C; Ultravist; Ultravist 300; Ultravist 370; ZK 35760. Grades: 98%. CAS No. 73334-07-3. Molecular formula: C18H24I3N3O8. Mole weight: 791.11. | |
| IOX2 | IOX2 is a specific prolyl hydroxylase-2 (PHD2) inhibitor with IC50 of 22 nM. Synonyms: IOX2; IOX-2; IOX 2. CAS No. 931398-72-0. Molecular formula: C19H16N2O5. Mole weight: 352.346. | |
| Ipatasertib | Ipatasertib, also known as GDC-0068 is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Akt inhibitor GDC-0068 binds to and inhibits the activity of Akt in a non-ATP-competitive manner, which may result in the inhibition of the PI3K/Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis. Activation of the PI3K/Akt signaling pathway is frequently associated with tumorigenesis and dysregulated PI3K/Akt signaling may contribute to tumor resistance to a variety of antineoplastic agents. Uses: Antineoplastic agents. Synonyms: GDC-0068; GDC0068; GDC 0068; RG7440; RG-7440; RG 7440; Ipatasertib. CAS No. 1001264-89-6. Molecular formula: C24H32ClN5O2. Mole weight: 458.0. | |
| IPI-549 | IPI-549, a dihydroisoquinolin derivative, has been found to be a phosphatidylinositol 3 kinase gamma inhibitor, could exhibit antineoplastic activity in solid tumors. It is still under Phase I trial. IC50: 16 nM (PI3Kγ), 3.2 μM (PI3Kα), 3.5 μM (PI3Kβ), >8.4 μM (PI3Kδ). Synonyms: IPI-549; IPI 549; IPI549; SCHEMBL16629991; (S)-2-amino-N-(1-(8-((1-methyl-1H-pyrazol-4-yl)ethynyl)-1-oxo-2-phenyl-1,2-dihydroisoquinolin-3-yl)ethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide. Grades: 98%. CAS No. 1693758-51-8. Molecular formula: C30H24N8O2. Mole weight: 528.58. | |
| Ipragliflozin | Ipragliflozin is a highly potent and selective SGLT2 inhibitor and has little and NO potency for SGLT1/3/4/5/6. Uses: Sodium-glucose transporter 2 inhibitors. Synonyms: ASP1941; ASP-1941; ASP 1941; Ipragliflozin. Trade name: Suglat. Grades: >98%. CAS No. 761423-87-4. Molecular formula: C21H21FO5S. Mole weight: 404.45. | |
| Ipratropium Bromide Impurity E | Synonyms: 3-Hydroxy-2-phenyl-propionic acid 8-isopropyl-8-aza-bicyclo[3.2.1]oct-3-yl ester. Grades: > 95%. CAS No. 183626-76-8. Molecular formula: C19H27NO3. Mole weight: 317.43. | |
| Ipratropium Impurity A | an impurity of Ipratropium (Bromide Monohydrate). Synonyms: endo-3-Hydroxy-8-isopropyl-8-methyl-8-azoniabicyclo[3.2.1]octane bromide; N-Isopropyltropinium bromide. Grades: > 95%. CAS No. 58005-18-8. Molecular formula: C11H22BrNO. Mole weight: 264.2. | |
| IR-783 | IR-783 is a cyanine dye used for labeling glycoprotein activity in tumors. Synonyms: 3H-Indolium, 2-[2-[2-chloro-3-[2-[1,3-dihydro-3,3-dimethyl-1-(4-sulfobutyl)-2H-indol-2-ylidene]ethylidene]-1-cyclohexen-1-yl]ethenyl]-3,3-dimethyl-1-(4-sulfobutyl)-, inner salt, sodium salt (1:1); 3H-Indolium, 2-[2-[2-chloro-3-[[1,3-dihydro-3,3-dimethyl-1-(4-sulfobutyl)-2H-indol-2-ylidene]ethylidene]-1-cyclohexen-1-yl]ethenyl]-3,3-dimethyl-1-(4-sulfobutyl)-, inner salt, monosodium salt; ADS 780WS; IR 783; IR783; S 0121; S 0121 (dye); 2-[2-[2-Chloro-3-[2-[1,3-dihydro-3,3-dimethyl-1-(4-sulfobutyl)-2H-indol-2-ylidene]-ethylidene]-1-cyclohexen-1-yl]-ethenyl]-3,3-dimethyl-1-(4-sulfobutyl)-3H-indolium hydroxide, inner salt, sodium salt. Grades: ≥95%. CAS No. 115970-66-6. Molecular formula: C38H46ClN2NaO6S2. Mole weight: 749.35. | |
| IRAK-1-4 Inhibitor I | IRAK-1-4 Inhibitor I is a novel benzimidazole that is a potent inhibitor of interleukin-1 receptor-associated kinases 1-4 (IRAK 1-4). Synonyms: Benzamide, N-[1-[2-(4-morpholinyl)ethyl]-1H-benzimidazol-2-yl]-3-nitro-. Grades: >98%. CAS No. 509093-47-4. Molecular formula: C20H21N5O4. Mole weight: 395.41. | |
| Irak4-IN-1 | Irak4-IN-1 is an inhibitor of interleukin-1 receptor associated kinase 4 (IRAK4). Synonyms: Irak4-IN-1; Irak4 IN 1; 4-[(4-morpholin-4-ylcyclohexyl)amino]quinazoline-6-carbonitrile. CAS No. 1820787-94-7. Molecular formula: C19H23N5O. Mole weight: 337.427. | |
| IRAK4-IN-3 | IRAK4-IN-3 is a compound with exceptional potency and selectivity against interleukin-1 receptor-associated kinase 4 (IRAK4), an inflammation-linked kinase. This compound has displayed tremendous promise in the treatment of autoimmune conditions, including rheumatoid arthritis and systemic lupus erythematosus. As such, it represents a significant advance in the field of molecular therapeutics targeting inflammatory disorders. Synonyms: IRAK4-IN-3 is an IRAK4 inhibitor. CAS No. 2196204-23-4. Molecular formula: C21H31N5O2. Mole weight: 385.5. | |
| Irbesartan Impurity 15 sodium salt | An impurity of Irbesartan, an angiotensin II receptor blocker used to treat hypertension and heart failure. Synonyms: sodium 5-(4'-(azidomethyl)-[1,1'-biphenyl]-2-yl)tetrazol-1-ide. CAS No. 1145664-35-2. Molecular formula: C14H10N7Na. Mole weight: 299.27. | |
| Irbesartan Related Compound A | A metabolite of Irbesartan, an angiotensin II receptor blocker used for the treatment of high blood pressure, heart failure, and diabetic kidney disease. Synonyms: 1-pentanoylamino-cyclopentanecarboxylic acid [2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-amide. Grades: > 95%. CAS No. 748812-53-5. Molecular formula: C25H30N6O2. Mole weight: 446.56. | |
| Irbinitinib | Irbinitinib,also known as ARRY-380 and ONT-380, is an orally bioavailable inhibitor of the human epidermal growth factor receptor tyrosine kinase ErbB-2 (also called HER2) with potential antineoplastic activity. ErbB-2 is overexpressed in a variety of cancers and plays an important role in cellular proliferation and differentiation. Uses: Antineoplastic agents. Synonyms: ARRY-380; ARRY 380; ARRY380; ONT-380; ONT-380; ONT-380. Grades: 0.98. CAS No. 937263-43-9. Molecular formula: C26H24N8O2. Mole weight: 480.532. | |
| Irinotecan EP Impurity H | An impurity of Irinotecan, a Topoisomerase I inhibitor used for the treatment of colon cancer and small cell lung cancer. Synonyms: (S)-11-Ethyl-4-hydroxy-4-methyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl [1,4'-bipiperidine]-1'-carboxylate; 4-methyl irinotecan analogue. Molecular formula: C32H36N4O6. Mole weight: 572.65. | |
| Irinotecan EP Impurity K | An impurity of Irinotecan, a Topoisomerase I inhibitor used for the treatment of colon cancer and small cell lung cancer. Synonyms: (4S)-4-ethyl-4-hydroxy-11-(1-hydroxypropyl)-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino-[1,2-b]quinolin-9-yl 1,4'-bipiperidine-1'-carboxylate. Molecular formula: C34H40N4O7. Mole weight: 616.70. | |
| Irinotecan EP Impurity L | An impurity of Irinotecan, a Topoisomerase I inhibitor used for the treatment of colon cancer and small cell lung cancer. Synonyms: (R)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl [1,4'-bipiperidine]-1'-carboxylate; irinotecan enantiomer. CAS No. 1255644-71-3. Molecular formula: C33H38N4O6. Mole weight: 586.68. | |
| Irinotecan Hydrochloride Trihydrate | The hydrochloride salt of Irinotecan. Irinotecan is a prodrug that can be activated to 7-ethyl-10-hydroxy-camptothecin (SN-38) by the carboxylesterase-converting enzyme. SN-38 inhibits topoisomerase I to suppress DNA replication and promote cell death. Synonyms: CPT-11 HCl Trihydrate; CPT 11 HCl Trihydrate; CPT11 HCl Trihydrate; Irinotecan Hcl Trihydrate; UNII-042LAQ1IIS. Grades: >98%. CAS No. 136572-09-3. Molecular formula: C33H38N4O6.HCl.3H2O. Mole weight: 677.18. | |
| Irinotecan Related Compound C | An impurity of Irinotecan, a Topoisomerase I inhibitor used for the treatment of colon cancer and small cell lung cancer. Synonyms: 11-Ethyl-4-hydroxy-4-methyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl (1,4'-bipiperidine)-1'-carboxylate hydrochloride; USP Irinotecan Related Compound C. Molecular formula: C32H37ClN4O6. Mole weight: 609.11. | |
| Irinotecan Related Compound D | An impurity of Irinotecan, a Topoisomerase I inhibitor used for the treatment of colon cancer and small cell lung cancer. Synonyms: (R)-9-[(1,4'-Bipiperidine)-1'-carbonyloxy]-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1Hpyrano[3',4':6,7]indolizino[1,2-b]quinoline hydrochloride trihydrate; USP Irinotecan Related Compound D. Molecular formula: C33H45ClN4O9. Mole weight: 677.18. | |
| Isavuconazole | Isavuconazole is a new triazole currently undergoing phase III clinical trials. This compound has shown in vitro activity against a large number of clinical important yeasts and molds including Aspergillus spp., Fusarium spp., Scedosporium spp., Candida spp., the Zygomycetes and Cryptococcus spp. Uses: Antifungal agents. Synonyms: BAL4815; BAL-4815; BAL 4815; RO 0094815; RO-0094815; RO0094815; Cresemba. Grades: >98%. CAS No. 241479-67-4. Molecular formula: C22H17F2N5OS. Mole weight: 437.47. | |
| Isavuconazole Impurity 24 | An impurity of Isavuconazole, a triazole antifungal agent with broad spectrum of activity. Synonyms: 4-(2-((1S,2R)-2-(2,5-difluorophenyl)-3-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl)-4-thiazolyl)-benzonitrile. CAS No. 1176988-44-5. Molecular formula: C22H17F2N5OS. Mole weight: 437.47. | |
| Isavuconazole Impurity 40 | An impurity of Isavuconazole, a triazole antifungal agent with broad spectrum of activity. Synonyms: 4-(2-((1R,2S)-2-(2,5-difluorophenyl)-3-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl)-4-thiazolyl)-benzonitrile. CAS No. 1797905-83-9. Molecular formula: C22H17F2N5OS. Mole weight: 437.47. | |
| Isepamicin Sulphate | Isepamicin Sulphate, an aminoglycoside antibiotic, inhibits bacterial protein synthesis by targeting the bacterial 30S ribosomal subunit. Synonyms: isepamicin sulfate; Isepamicin monosulfate. Grades: >98%. CAS No. 67814-76-0. Molecular formula: C22H45N5O16S. Mole weight: 667.68. | |
Our database is helping our users find suppliers everyday.
