BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| GalNAc C3 CPG | GalNAc-C3-CPG, a novel therapeutic agent, holds significant potential in the fight against viral infections. Its innovative and intricate architecture aptly mimics viral RNA, thereby facilitating the activation of the immune system and a consequential robust antiviral response. Synonyms: GalNAc C3 CPG 1000Å; (4-(Trimethoxytrityloxymethyl)-1-(6-(4-(3,4,6-O-triacetyl-2-acetylamino-2-deoxy-β-D-galactopyranosyl)butanamido)hexanoyl)piperidin-4-yl)methyl-O-succinoyl CPG. |  |
| GalNAc-Cluster-COOH | GalNAc-Cluster-COOH is a functionalized ligand designed for targeted delivery to hepatocytes via the asialoglycoprotein receptor (ASGPR). It features a trivalent GalNAc (N-acetylgalactosamine) cluster linked to a PEG spacer and terminated with a carboxylic acid group, which facilitates conjugation to other molecules. This compound is widely used in the development of lysosome-targeting chimeras (LYTACs) and for delivering nucleic acids or protein complexes to liver cells in a cell-specific manner. Its structure and valency enhance binding affinity to ASGPR, enabling efficient internalization and delivery of therapeutic agents. Synonyms: N2,N6-Bis[2-[2-[2-[2-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethoxy]ethoxy]acetyl]-L-lysyl-N6-[2-[2-[2-[2-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethoxy]ethoxy]acetyl]-L-lysine; (17S,20S)-1-(((2R,3R,4R,5R,6R)-3-Acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-20-(1-(((2R,3R,4R,5R,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-11-oxo-3,6,9-trioxa-12-azahexadecan-16-yl)-17-(2-(2-(2-(2-(((2R,3R,4R,5R,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethoxy)acetamido)-11,18-dioxo-3,6,9-trioxa-12,19-diazahenicosan-21-oic acid. Grade: >98%. CAS No. 1332358-22-1. Molecular formula: C60H107N7O33. Mole weight: 1454.52. | |
| Galnac GLS-15 | GalNAc GLS-15 is a novel GalNAc-derived small molecule structure designed for siRNA delivery. It is engineered to leverage the high affinity of GalNAc for the asialoglycoprotein receptor (ASGPR) on hepatocytes, enabling efficient liver-targeted delivery of siRNA molecules. This compound is part of the broader GalNAc delivery system, which has been widely adopted for RNA interference (RNAi) therapies due to its ability to enhance drug uptake and reduce off-target effects. Synonyms: GLS15; GalNAc GLS-15. Grade: >98%. CAS No. 2920438-06-6. Molecular formula: C82H132N11O37P. Mole weight: 1894.97. | |
| GalNAc-hexyl-threoninol-CPG | GalNAc-hexyl-threoninol-CPG is a solid-supported GalNAc (N-acetylgalactosamine) monomer designed for the efficient synthesis of GalNAc-conjugated oligonucleotides. It features a GalNAc moiety attached to a threoninol scaffold via a hexyl linker, with the primary hydroxyl group protected by a dimethoxytrityl (DMT) group. The compound is immobilized on a solid support (controlled-pore glass, CPG) through a succinylated linker, facilitating its use in solid-phase synthesis. This configuration allows for the convenient and scalable incorporation of GalNAc units into oligonucleotides, enhancing their targeting efficiency to hepatocytes via the asialoglycoprotein receptor (ASGPR). GalNAc-hexyl-threoninol-CPG serves as a versatile building block for developing targeted nucleic acid therapeutics with improved cellular uptake and specificity. | |
| GalNAc-L96-Amide | GalNAc-L96-Amide is a specialized compound within the GalNAc series, designed for targeted delivery of nucleic acid drugs to hepatocytes. This molecule features a triantennary GalNAc (N-acetylgalactosamine) core linked to a longer PEG-based linker and terminated with an amide group. The GalNAc core serves as a high-affinity ligand for the asialoglycoprotein receptor (ASGPR), which is highly expressed on hepatocytes, enabling efficient liver-targeted delivery. The compound is used primarily for the synthesis of GalNAc-siRNA conjugates, which leverage the ASGPR pathway to enhance the uptake and efficacy of siRNA molecules in the liver. This targeted delivery system avoids the immunogenicity associated with lipid-based delivery methods and improves the safety and specificity of nucleic acid therapies. GalNAc-L96-Amide is also a key intermediate in the development of advanced drug delivery systems, particularly for RNA interference (RNAi) therapies. Grade: >98%. | |
| GalNac-L96 analog | GalNAc-L96 analog is an intermediate used in the synthesis of ligands targeting the asialoglycoprotein receptor (ASGPR), a receptor highly expressed on hepatocytes and involved in the internalization and degradation of desialylated glycoproteins. It features a triantennary GalNAc (N-acetylgalactosamine) structure designed to enhance the targeting and delivery of nucleic acid drugs to liver cells. It is commonly used in the development of GalNAc-siRNA conjugates, which leverage the high affinity of GalNAc for ASGPR to facilitate efficient cellular uptake and endosomal release of siRNA molecules, thereby improving the efficacy of RNA-based therapies. Synonyms: N-Acetylgalactosamine-L96 analog; GalNAc-L96; N-acetyl-D-Galactosamine-L96 analog; (2S,4R)-2-[[Bis(4-methoxyphenyl)phenylmethoxy]methyl]-4-hydroxy-λ-oxo-N-[2-[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]-1,1-bis[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]ethyl]-1-pyrrolidinedodecanamide. Grade: ≥95%. CAS No. 1159408-72-6. Molecular formula: C117H175N11O42. Mole weight: 2407.69. | |
| GalNAc-L96-CPG | GalNAc-L96-CPG is a solid support reagent designed for the synthesis of GalNAc-conjugated oligonucleotides, particularly siRNA, for targeted delivery applications. It consists of a triantennary GalNAc ligand (specifically the L96 variant) covalently attached to a controlled pore glass (CPG) support via a linker. The GalNAc moiety serves as a high-affinity ligand for the asialoglycoprotein receptor (ASGPR), which is abundantly expressed on hepatocytes, enabling efficient receptor-mediated endocytosis of the conjugated oligonucleotide into liver cells. This system facilitates the development of RNA interference (RNAi) therapeutics, such as GalNAc-siRNA conjugates, by enhancing cellular uptake and pharmacokinetic properties. Synonyms: 3'-GalNAc CPG 1000; GalNAc-L96 CPG. | |
| GalNac-L96 free base | GalNAC-L96 free base is a triantennary GalNAc ligand that can be used for the synthesis of GalNAC-SiRNA and for the delivery of nucleic acid drugs. GalNAc is a ligand for the asialal glycoprotein receptor (ASGPR). Synonyms: L-96; Butanedioic acid, 1-[(3R,5S)-5-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-1-[1,12,19,25-tetraoxo-14,14-bis[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-29-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-16-oxa-13,20,24-triazanonacos-1-yl]-3-pyrrolidinyl] ester; 1-[(3R,5S)-5-[[Bis(4-methoxyphenyl)phenylmethoxy]methyl]-1-[1,12,19,25-tetraoxo-14,14-bis[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-29-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-16-oxa-13,20,24-triazanonacos-1-yl]-3-pyrrolidinyl] butanedioate; GalNAc-L96-SA; L-96-Succinic Acid; GalNAc-L96-Succinate. Grade: 98%. CAS No. 1159408-61-3. Molecular formula: C121H179N11O45. Mole weight: 2507.76. | |
| GalNAc-L96 Linker-Acid | GalNAc-L96 Linker-Acid is a specialized chemical compound designed for the synthesis of targeted nucleic acid delivery systems. It features a triantennary GalNAc (N-acetylgalactosamine) cluster linked to a longer PEG-based linker, terminating with a carboxylic acid group. This structure allows for efficient conjugation to oligonucleotides, such as siRNA, enabling targeted delivery to hepatocytes via the asialoglycoprotein receptor (ASGPR). The compound is widely used in the development of RNA interference (RNAi) therapies, particularly for liver-related diseases. This linker is a key intermediate in the synthesis of GalNAc-siRNA conjugates, which have demonstrated superior stability and gene silencing efficiency compared to traditional lipid nanoparticle delivery systems. Synonyms: 12,19,25-Trioxo-14,14-bis[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-29-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-16-oxa-13,20,24-triazanonacosanoic acid; 1-(((2R,3R,4R,5R,6R)-3-Acetamido-4,5-diacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-16,16-bis((3-((3-(5-(((2R,3R,4. Grade: ≥97%. CAS No. 1426159-34-3. Molecular formula: C91H148N10O39. Mole weight: 2006.22. | |
| GalNAc-L96 Linker-Azide | GalNAc-L96 Linker-Azide is a specialized chemical compound designed for the development of targeted nucleic acid delivery systems. It features a triantennary GalNAc (N-acetylgalactosamine) cluster linked to a PEG-based linker, terminating with an azide group. This structure allows for efficient conjugation to oligonucleotides or other therapeutic agents through click chemistry, enabling targeted delivery to hepatocytes via the asialoglycoprotein receptor (ASGPR). GalNAc-L96 Linker-Azide is particularly useful in the synthesis of GalNAc-siRNA conjugates, which have demonstrated high efficiency in liver-targeted gene silencing. The azide group provides a convenient handle for conjugation, making it suitable for the development of advanced drug delivery systems, especially for RNA interference (RNAi) therapies. Grade: ≥97%. CAS No. 2135330-72-0. Molecular formula: C90H147N13O37. Mole weight: 2003.22. | |
| GalNAc-Lipid GL3 | GalNAc-Lipid GL3 is a first-generation GalNAc-based ligand designed for targeted delivery of therapeutic agents to hepatocytes via the asialoglycoprotein receptor (ASGPR). It features a trivalent GalNAc structure attached to a TRIS scaffold, which facilitates efficient binding to ASGPR and subsequent cellular uptake. In preclinical studies, GalNAc-Lipid GL3 was formulated into lipid nanoparticles (LNPs) and tested for its ability to deliver CRISPR base editors to the liver. While effective, GL3 demonstrated lower editing efficiency compared to its second-generation counterpart, GalNAc-Lipid GL6, which achieved higher liver editing rates in both LDLR-deficient and wild-type mice. This suggests that GL3's TRIS scaffold may be less optimal than the lysine-based scaffold used in GL6 for ASGPR-mediated uptake and delivery. Despite this, GalNAc-Lipid GL3 remains an important reference in the development of targeted liver delivery systems, highlighting the potential of GalNAc ligands for non-LDLR-dependent therapies. Grade: >98%. | |
| GalNAc-Lipid GL5 | GalNAc-Lipid GL5 is a targeting ligand designed for lipid nanoparticles (LNPs) with a short 12-unit PEG linker. It enables non-LDLR (low-density lipoprotein receptor)-dependent delivery of therapeutic agents to hepatocytes. However, compared to GL6 with a longer PEG linker, GL5 exhibits lower liver-targeting efficiency. For instance, in experiments targeting the _Angptl3_ gene in mice, GL5 achieved only 18% liver editing efficiency, while GL6 reached 56%. This suggests that the shorter PEG linker in GL5 may limit its binding affinity to ASGPR (asialoglycoprotein receptor) on hepatocytes. Despite its lower efficiency, GL5 remains valuable for understanding the structure-function relationship in GalNAc-LNP design. Grade: ≥98%. | |
| GalNAc-Lipid GL6 | GalNAc-Lipid GL6 is a potent and scalable ligand designed for targeted liver delivery of therapeutic agents, particularly in the context of CRISPR base editing therapies. It features a multi-valent N-acetylgalactosamine (GalNAc) structure that binds specifically to the asialoglycoprotein receptor (ASGPR), enabling efficient uptake by hepatocytes. This ligand is part of the second-generation GalNAc design, which incorporates a lysine-based scaffold and a longer PEG spacer (34-38 units) compared to earlier designs. The combination of a 1,2-O-dioctadecyl-sn-glyceryl (DSG) lipid anchor and the optimized PEG spacer enhances the stability and delivery efficiency of lipid nanoparticles (LNPs) in vivo. In preclinical studies, GalNAc-Lipid GL6 demonstrated superior performance in liver-targeted gene editing compared to other GalNAc ligands, achieving high editing rates in both wild-type and LDLR-deficient mice and non-human primates. This ligand has shown significant potential for non-LDLR-dependent delivery of CRISPR therapies, making it a valuable tool for treating genetic disorders and metabolic diseases. Grade: 98%. | |
| GalNAc-Lipid GL7 | GalNAc-Lipid GL7 is a ligand designed to optimize the delivery of lipid nanoparticles (LNPs) to hepatocytes via non-LDLR (low-density lipoprotein receptor) dependent pathways. It is based on Design 2, which features a lysine scaffold with three GalNAc units attached through a 36-unit PEG linker. The primary goal of GL7 is to evaluate the impact of different lipid anchors on the stability and delivery efficiency of LNPs. Specifically, GL7 incorporates a cholesteryl (Chol) lipid anchor, which was tested alongside other lipid anchors like 1,2-O-dioctadecyl-sn-glyceryl (DSG) and arachidoyl (C20) to assess their effects on ASGPR (asialoglycoprotein receptor) recognition and binding. However, experiments in Ldlr-mice demonstrated that the DSG lipid anchor in GL6 was significantly more effective for liver-targeted gene editing compared to the cholesterol anchor in GL7, with an editing efficiency of 56% for DSG versus 4% for cholesterol. This suggests that GL7, with its cholesterol anchor, is less efficient for non-LDLR-dependent delivery of LNPs to hepatocytes. Grade: ≥98%. | |
| GalNAc-Lipid GL9 | GalNAc-Lipid GL9 is a ligand designed for lipid nanoparticles (LNPs) to facilitate non-LDLR (low-density lipoprotein receptor)-dependent delivery of therapeutic agents to hepatocytes. It is based on Design 2, which uses a lysine scaffold with three GalNAc units attached through a PEG linker. The primary goal of GL9 is to evaluate the impact of different lipid anchors on the stability and delivery efficiency of LNPs. In GL9, the lipid anchor is an arachidoyl (C20) moiety, which was tested alongside other lipid anchors like 1,2-O-dioctadecyl-sn-glyceryl (DSG) and cholesterol (Chol) to assess their effects on ASGPR (asialoglycoprotein receptor) recognition and binding. However, experiments in LDLR-deficient mice demonstrated that the DSG lipid anchor in GL6 was significantly more effective for liver-targeted gene editing compared to the arachidoyl (C20) anchor in GL9. Specifically, the editing efficiency of GL6 with DSG was 56%, while GL9 with C20 achieved only 8% efficiency. This indicates that GL9, with its C20 lipid anchor, is less efficient for non-LDLR-dependent delivery of LNPs to hepatocytes. Grade: ≥98%. | |
| GalNAc-NAG-25 Phosphoramidite | GalNAc-NAG-25 Phosphoramidite is a modified phosphoramidite that incorporates a N-acetylgalactosamine (GalNAc) moiety linked to the NAG component, specifically designed for the synthesis of oligonucleotides. This compound enhances the stability and bioactivity of nucleic acids, particularly in applications involving targeted delivery and therapeutic interventions. Its unique structural features allow for improved interactions with cellular receptors, making GalNAc-NAG-25 Phosphoramidite valuable in the development of glyco-engineered therapeutics and in the field of glycobiology, where carbohydrate-based modifications play a crucial role in biological processes. Synonyms: NAG-25; NAG 25; NAG25; GalNAc NAG-25 Phosphoramidite; N2-[23-[Bis(1-methylethyl)amino]-26-cyano-1-oxo-4,7,10,13,16,19,22,24-octaoxa-23-phosphahexacos-1-yl]-N-[2-[2-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethyl]-L-γ-glutamyl-N,N2-bis[2-[2-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethyl]-L-glutamamide. Grade: ≥95%. CAS No. 2130036-52-9. Molecular formula: C88H145N10O43P. Mole weight: 2062.13. | |
| GalNAc-PEG-Cluster-1-CPG | GalNAc-PEG-Cluster-1-CPG is a specialized reagent used for the synthesis of oligonucleotide conjugates, particularly for liver-targeted drug delivery. It combines N-acetylgalactosamine (GalNAc) with a polyethylene glycol (PEG) linker and a controlled pore glass (CPG) support to facilitate the attachment of GalNAc clusters to oligonucleotides. This structure enhances the targeting of siRNA or other nucleic acid drugs to hepatocytes via the asialoglycoprotein receptor (ASGPR), improving cellular uptake and therapeutic efficacy. Grade: ≥98%. | |
| Galnon TFA | Galnon is a non-peptide galanin GAL1 and GAL2 receptor agonist (Ki = 11.7 and 34.1 μM, respectively) with anticonvulsant, anxiolytic, anorectic and amnestic activities. It stimulates insulin release in isolated pancreatic islets from normal and diabetic rats. Synonyms: L-Lysinamide, 3-cyclohexyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-, 2,2,2-trifluoroacetate (1:1); Fmoc-Cha-Lys-AMC.TFA; 3-Cyclohexyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-lysinamide trifluoroacetate salt; Galnon trifluoroacetate salt; Galnon Trifluoroacetate. Grade: ≥95%. CAS No. 1217448-19-5. Molecular formula: C40H46N4O6.C2HF3O2. Mole weight: 792.84. | |
| Galunisertib | Galunisertib is a potent and selective inhibitor of transforming growth factor beta receptor (TGF-βR) kinase. It was shown to inhibit self-renewal of cancer stem cells. Synonyms: LY 2157299; LY-2157299; 4-[2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]quinoline-6-carboxamide. Grade: >98%. CAS No. 700874-72-2. Molecular formula: C22H19N5O. Mole weight: 369.428. | |
| gama-Glu-Lys20-Liraglutide | An impurity of Liraglutide. Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used primarily to treat type 2 diabetes (T2D) and obesity. Synonyms: His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(gama-Glu)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly; glutamate-Lirapeptide (synthetic); HAEGTFTSDVSSYLEGQAA-Lys(γ-Glu)-EFIAWLVRGRG; L-Histidyl-L-alanyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[L-γ-glutamyl]-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginylglycine; [γ-Glu-Lys20]-Liraglutide. Grade: ≥95%. CAS No. 2135342-94-6. Molecular formula: C156H235N43O50. Mole weight: 3512.85. | |
| Gama-Hydroxy Baclofen | Gama-Hydroxy Baclofen is the impurity of Baclofen, which is a specific GABA-B receptor agonist with muscle relaxant effect. Molecular formula: C10H12ClNO3. Mole weight: 229.66. | |
| Gamithromycin-[d5] | Isotope labelled analog of Gamithromycin, a macrolide compound which is known to have antibacterial activity, and is useful in mammals' bacterial infections treatment. Antibiotic. Synonyms: (2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-7-propyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-7-azacyclopentadecan-15-one-d5; ML 1709460-d5; Gamithromycin-d5; Zactran-d5. Grade: 95%. CAS No. 2734920-04-6. Molecular formula: C40H71D5N2O12. Mole weight: 782.08. | |
| Gamma-Aminobutyric Acid Almotriptan | A metabolite of Almotriptan. Synonyms: Almotriptan Metabolite M2. Grade: > 95%. CAS No. 603137-41-3. Molecular formula: C17H25N3O4S. Mole weight: 367.47. | |
| gamma-(BBT)-ATP | Gamma-(BBT)-ATP is a potent and selective inhibitor used in biomedicine for the treatment of various diseases. It specifically targets adenosine triphosphate (ATP) in the gamma-(BBT) pathway, offering potential therapeutic options for metabolic disorders, neurological conditions, and certain types of cancer. This product plays a critical role in accurately modulating ATP levels to restore cellular homeostasis and improve overall health. Synonyms: gamma-[2'(2-benzothiazoyl)-6'-hydroxybenzothiazole)-adenosine-5'-triphosphate sodium salt. Grade: 95%. Molecular formula: C24H22N7O13P3S2·xNa. Mole weight: 773.52 (free acid). | |
| gamma-(BBT)-GTP | gamma-(BBT)-GTP is a crucial compound in biomedicine used for studying the role of guanosine triphosphate (GTP) in cellular processes. This product plays a significant role in research related to GTP-binding proteins and signal transduction pathways. It aids in investigating diseases such as cancer, neurological disorders, and infectious diseases, thereby contributing to the development of potential therapeutics targeting GTP-related pathways. Synonyms: gamma-[2'(2-benzothiazoyl)-6'-hydroxybenzothiazole)-guanosine-5'-triphosphate sodium salt. Molecular formula: C24H22N7O14P3S2·xNa. Mole weight: 789.52 (free acid). | |
| Gamma-cyclodextrin phosphate sodium salt | Gamma-cyclodextrin phosphate sodium salt is a pharmaceutical excipient used to enhance the solubility, bioavailability and stability of poorly water-soluble drugs. It is also utilized in the treatment of inflammation, HIV and neurological disorders by delivering targeted therapeutics. Synonyms: γ-Cyclodextrin phosphate sodium salt; γ-Cyclodextrin, dihydrogen phosphate, sodium salt; Sodium γ-cyclodextrin phosphate. CAS No. 199684-62-3. Molecular formula: C48H80O40.xH3O4P.xNa. | |
| Gamma-cyclodextrin sulfate sodium salt | Gamma-cyclodextrin sulfate sodium salt is an esteemed constituent with proficiency in the encapsulation and conveyance of pharmacological compounds. Augmented by its sulfate moiety is an amplified aqueous solubility and perseveration are bestowed upon this invaluable compound. Synonyms: γ-cyclodextrin sulfate sodium salt. Molecular formula: C48H80-nO40·(SO3Na)n. | |
| gamma-DGG acetate | gamma-DGG acetate is a competitive blocker of AMPA receptor and is a broad spectrum glutamate receptor (GluR) antagonist. Synonyms: H-D-gGlu-Gly-OH.CH3CO2H; D-gamma-glutamyl-glycine acetic acid; N5-(carboxymethyl)-D-glutamine compound with acetic acid (1:1); γ-DGG acetate salt; γ-D-Glutamylglycine acetate salt. Grade: ≥95%. CAS No. 2935387-13-4. Molecular formula: C7H12N2O5.C2H4O2. Mole weight: 264.23. | |
| gamma-L-Glutamic acid 7-amido-4-methylcoumarin | L-Glutamic acid γ-(7-amido-4-methylcoumarin) is a substrate for aminopeptidase or the assay of γ-glutamyl transferase producing a blue fluorescent solution upon cleavage. Synonyms: H-GLU(AMC)-OH; L-Glutamic Acid Gamma-(7-Amido-4-Methylcoumarin). Grade: 98%. CAS No. 72669-53-5. Molecular formula: C15H16N2O5. Mole weight: 304.30. | |
| gamma-Lumicolchicine | gamma-Lumicolchicine is a novel and potent isomer of ultraviolet degradation products of colchicine. Synonyms: Colchicine Impurity G; γ-Lumicolchicine; [7S-(7α,7bα,10aα)]-N-(5,6,7,7b,8,10a-hexahydro-1,2,3,9-tetramethoxy-8-oxobenzo[a]cyclopenta[3,4]cyclobuta[1,2-c]cyclohepten-7-yl)acetamide; N-[(7S,7bS,10aR)-5,6,7,7b,8,10a-Hexahydro-1,2,3,9-tetramethoxy-8-oxobenzo[a]cyclopenta[3,4]cyclobuta[1,2-c]cyclohepten-7-yl]acetamide. Grade: ≥95%. CAS No. 6901-14-0. Molecular formula: C22H25NO6. Mole weight: 399.44. | |
| γ-Mangostin | gamma-Mangostin isolated from the fruit of Garcinia cambogia is an HIV protease inhibitor. gamma-Mangostin is cytotoxic to HL-60, SMMC-7721, A549, MCF-7, and SW480 cancer cells and BEAS-2B non-cancerous pulmonary epithelial cells in vitro (IC50s = 7.39, 6.57, 10.07, 5.33, 8.4, and 7.43 μM, respectively). Uses: Hiv protease inhibitor. Synonyms: Normangostin. Grade: 98%. CAS No. 31271-07-5. Molecular formula: C23H24O6. Mole weight: 396.43. | |
| gamma-Oryzanol | Gamma-oryzanol is a natural compound found in crude rice bran oil. It acts as a potent DNA methyltransferases (DNMTs) inhibitor in the striatum of mice. Uses: Hair care; body care; face care. Synonyms: Cycloartenyl ferulate; gamma Oryzanol; Oliver; Gammariza. Grade: 95%. CAS No. 11042-64-1. Molecular formula: C40H58O4. Mole weight: 602.89. | |
| gamma-secretase modulator 1 | gamma-secretase modulator 1 is a gamma-secretase modulator, useful for Alzheimer's disease. Synonyms: gamma-secretase modulator 1; 1172637-87-4; 4,5,6,7-Tetrahydro-N-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-4-phenyl-2-benzothiazolamine; N-[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]-4-phenyl-4,5,6,7-tetrahydro-1,3-benzothiazol-2-amine; VFSGAZRYSCNFDF-UHFFFAOYSA-N; SCHEMBL1616912; CHEMBL1915569; DTXSID90655321; XWB63787; AKOS030526283; CS-0329; NCGC00378743-01; HY-10043; MS-27256; F83676; A908573; [3-Methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-(4-phenyl-4,5,6,7-tetrahydro-benzothiazol-2-yl)-amine; N-[3-Methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-4-phenyl-4,5,6,7-tetrahydro-1,3-benzothiazol-2-amine. Grade: >98%. CAS No. 1172637-87-4. Molecular formula: C24H24N4OS. Mole weight: 416.54. | |
| gamma-secretase modulator 1 hydrochloride | gamma-secretase modulator 1 hydrochloride is a gamma-secretase modulator used in the treatment of Alzheimer's disease. Synonyms: N-[3-Methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-4-phenyl-4,5,6,7-tetrahydro-1,3-benzothiazol-2-amine hydrochloride (1:1); 2-Benzothiazolamine, 4,5,6,7-tetrahydro-N-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-4-phenyl-, hydrochloride (1:1). Grade: ≥98%. Molecular formula: C24H25ClN4OS. Mole weight: 453.00. | |
| gamma-secretase modulator 2 | gamma-secretase modulator 2, a triazole derivative, a potent and selective γ-secretase modulator so as to selectively attenuate production of Aβ(1-42) and hence has the potential for treatment of Alzheimer's disease. Synonyms: 6-fluoro-3-[4-[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]triazol-1-yl]-1-(2,2,2-trifluoroethyl)-4,5-dihydro-3H-1-benzazepin-2-one; gamma-secretase modulator 2; 1093978-89-2; SCHEMBL3040102; DTXSID70732149; C25H22F4N6O2; 3374AH; ABP000472; BCP9000905; CS-0310; HE070827; HE211077; HY-50754; DB-014988; W-5511; 2H-1-BENZAZEPIN-2-ONE,6-FLUORO-1,3,4,5-TETRAHYDRO-3-[4-[3-METHOXY-4-(4-METHYL-1H-IMIDAZOL-1-YL)PHENYL]-1H-1,2,3-TRIAZOL-1-YL]-1-(2,2,2-TRIFLUOROETHYL)-; 6-fluoro-1,3,4,5-tetrahydro-3-[4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1,2,3-triazol-1-yl]-1-(2,2,2-trifluoroethyl)-2H-1-Benzazepin-2-on; 6-Fluoro-1,3,4,5-tetrahydro-3-[4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1,2,3-triazol-1-yl]-1-(2,2,2-trifluoroethyl)-2H-1-benzazepin-2-one; 6-fluoro-3-{4-[3-methoxy-4-(4-methyl-1h-imidazol-1-yl)phenyl]-1h-1,2,3-triazol-1-yl}-1-(2,2,2-trifluoroethyl)-1,3,4,5-tetrahydro-2h-1-benzazepin-2-one; 6-FLUORO-3-{4-[3-METHOXY-4-(4-METHYLIMIDAZOL-1-YL)PHENYL]-1,2,3-TRIAZOL-1-YL}-1-(2,2,2-TRIFLUOROETHYL)-4,5-DIHYDRO-3H-1-BENZAZEPIN-2-ONE. CAS No. 1093978-89-2. Molecular formula: C25H22F4N6O2. Mole weight: 514.47. | |
| gamma-secretase modulator 3 | gamma-secretase modulator 3 is a γ-secretase inhibitor. Synonyms: 4-(4-fluorophenyl)-N-[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]-4,5,6,7-tetrahydro-1,3-benzothiazol-2-amine; gamma-secretase modulator 3; CS-1149; HY-50889; W-6019; CS 1149; HY 50889; W 6019; CS1149; HY50889; W6019; 1431697-84-5. CAS No. 1431697-84-5. Molecular formula: C24H23FN4OS. Mole weight: 434.53. | |
| gamma-Secretase modulators | gamma-Secretase Modulators is a potent modulator of γ-secretase derived from oxadiazine. (IC50: Aβ42 = 11 nM, Aβ total/ Aβ42 = 1170). Synonyms: (4R,7E,9aS)-7-[[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]methylidene]-4-(3,4,5-trifluorophenyl)-1,3,4,8,9,9a-hexahydropyrido[2,1-c][1,4]oxazin-6-one; gamma-Secretase Modulators; 937812-80-1; (E)-(4R,9aS)-7-[3-Methoxy-4-(4-methyl-1H-imidazol-1-yl)benzylidene]-4-(3,4,5-trifluorophenyl)hexahydropyrido[2,1-c][1,4]oxazin-6-one; QCR-41; SCHEMBL2589995; DTXSID90647302; C26H24F3N3O3; hexahydro-7-[[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]methylene]-4-(3,4,5-trifluorophenyl)-(4R,7E,9aS)-Pyrido[2,1-c][1,4]oxazin-6(1H)-one; 3690AH; ZINC95644683. CAS No. 937812-80-1. Molecular formula: C26H24F3N3O3. Mole weight: 483.48. | |
| Ganaplacide hydrochloride | Ganaplacide hydrochloride is a first-in-class, orally active imidazolopiperazine antimalarial agent. It is active against a broad range of Plasmodium species, including drug-resistant parasites. Ganaplacide hydrochloride is parasiticidal against both asexual and sexual blood stages as well as the liver stages of the parasite. Synonyms: KAF156 hydrochloride; GNF156 hydrochloride. Grade: 97%. Molecular formula: C22H24ClF2N5O. Mole weight: 447.91. | |
| Ganaplacide phosphate | Ganaplacide phosphate is a first-in-class, orally active imidazolopiperazine antimalarial agent. It is active against a broad range of Plasmodium species, including drug-resistant parasites. Synonyms: KAF156 phosphate; GNF156 phosphate. Molecular formula: C22H26F2N5O5P. Mole weight: 509.44. | |
| Ganciclovir Bisvaline Ester | Ganciclovir Bisvaline Ester is an extraordinary compound, used for studying various viral infections. Derived from the renowned antiviral drug, Ganciclovir, this prodigious compound exhibits unparalleled efficacy in treating cytomegalovirus. Grade: > 95%. Molecular formula: C19H31N7O6. Mole weight: 453.50. | |
| Ganciclovir Diacetyl Impurity | Ganciclovir Diacetyl Impurity is an impurity of Ganciclovir. Ganciclovir is an antiviral drug for feline herpesvirus type-1 with IC50 of 5.2 μM. Synonyms: 2-((2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy)propane-1,3-diyl diacetate; 9-(1,3-diacetate-2-propoxymethyl)guanine; Ganciclovir Impurity 10. CAS No. 86357-19-9. Molecular formula: C13H17N5O6. Mole weight: 339.31. | |
| Ganciclovir Dipropionate | Ganciclovir Dipropionate is a robust antiviral agent in the biomedical sector, extensively employed for studying cytomegalovirus (CMV) infections by impeding viral DNA synthesis. Synonyms: Ganciclovir Impurity I; 2-Amino-1,9-dihydro-9-[[2-(1-oxopropoxy)-1-[(1-oxopropoxy)methyl]ethoxy]methyl]-6H-purin-6-one; 2-[(2-AMino-6-oxo-1,6-dihydro-9H-purin-9-yl)Methoxy]propane-1,3-diylDipropanoate. Grade: > 95%. CAS No. 86357-20-2. Molecular formula: C15H21N5O6. Mole weight: 367.36. | |
| Ganciclovir EP Impurity C | Ganciclovir EP Impurity C is an Impurity of Ganciclovir. It is a sugar modified acyclic analogue of guanosine. It has potential to exhibit virucidal activity. Synonyms: 2'-Monodehydroxy-2'-chloro Ganciclovir; 9-[[2-Chloro-1-(hydroxymethyl)ethoxy]methyl]guanine; 2-Amino-9-[[2-chloro-1-(hydroxymethyl)ethoxy]methyl]-1,9-dihydro-6H-purin-6-one. Grade: > 95%. CAS No. 108436-36-8. Molecular formula: C9H12ClN5O3. Mole weight: 273.68. | |
| Ganciclovir EP Impurity E | Iso Ganciclovir is an impurity of the anti-viral Gangiclovir. Uses: Antiviral agents. Synonyms: Iso Ganciclovir; Isoganciclovir; iso-Ganciclovir; 2-Amino-9-[(2,3-dihydroxypropoxy)methyl]-1,9-dihydro-6H-purin-6-one; ((RS)-2-Amino-9-(2,3-dihydroxy-propoxymethyl)-1,9-dihydro-purin-6-one); Ganciclovir Related Compound A (USP). Grade: 98%. CAS No. 86357-09-7. Molecular formula: C9H13N5O4. Mole weight: 255.23. | |
| Ganciclovir EP Impurity H | Ganciclovir EP Impurity H is an impurity of Ganciclovir. Ganciclovir is an antiviral drug for feline herpesvirus type-1 with IC50 of 5.2 μM. Synonyms: 2-((2-Amino-6-hydroxy-7H-purin-7-yl)methoxy)-1,3-propanediol; Ganciclovir Impurity 07; 2-amino-7-(((1,3-dihydroxypropan-2-yl)oxy)methyl)-1,7-dihydro-6H-purin-6-one. CAS No. 84222-50-4. Molecular formula: C9H13N5O4. Mole weight: 255.23. | |
| Ganciclovir EP Impurity J | Ganciclovir EP Impurity J is an impurity of Ganciclovir. Ganciclovir is an antiviral drug for feline herpesvirus type-1 with IC50 of 5.2 μM. Synonyms: 2-(2-(Propanoylamino)-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy)propane-1,3-diyl dipropanoate; Ganciclovir Tripropionate; O,O',N-Tripropanal Ganciclovir; Ganciclovir Impurity 09. Grade: 95% by HPLC. CAS No. 177216-32-9. Molecular formula: C18H25N5O7. Mole weight: 423.42. | |
| Ganciclovir Impurity A | Ganciclovir Impurity A is an impurity of Ganciclovir. Synonyms: 9-[[2-Chloroprop-2-en-1-yl)oxy]methyl]guanine; 2-amino-9-[[(2-chloroprop-2-en-yl)oxy]methyl]-1,9-dihydro-6H-purin-6-one. Grade: > 95%. CAS No. 1797982-93-4. Molecular formula: C9H10ClN5O2. Mole weight: 255.67. | |
| Ganciclovir Impurity D | Ganciclovir Impurity D. Synonyms: 2-AMino-1,9-dihydro-9-[[[2-hydroxy-1-(hydroxyMethyl)ethoxy]Methoxy]Methyl]-. Grade: > 95%. CAS No. 1346598-14-8. Molecular formula: C10H15N5O5. Mole weight: 285.26. | |
| Ganciclovir Impurity H | Ganciclovir Impurity H. Grade: > 95%. Molecular formula: C9H13N5O4. Mole weight: 255.24. | |
| Ganciclovir Impurity J | Ganciclovir Impurity J. Grade: > 95%. Molecular formula: C18H25N5O7. Mole weight: 423.43. | |
| Ganciclovir Impurity N | Ganciclovir Impurity N is an impurity of Valganciclovir. Synonyms: Ganciclovir mono-N-methyl valinate; 2-(RS)-[(Guanin-9-yl)methoxy]-3-hydroxypropyl N-methyl-L-valinate hydrochloride; N-Methyl-L-valine 2-(2-amino-6-oxo-1,6-dihydropurin-9-ylmethoxy)-3-hydroxypropyl ester monohydrochloride; N-Methylvalganciclovir hydrochlorid. Grade: > 95%. CAS No. 1401562-16-0. Molecular formula: C15H25N6O5Cl. Mole weight: 404.86. | |
| Ganciclovir Monoacetate | Ganciclovir Monoacetate is Ganciclovir derivative. Synonyms: Ganciclovir mono-O-acetate; 9-[[2-(Acetyloxy)-1-(hydroxymethyl)ethoxy]methyl]-2-amino-1,9-dihydro-6H-purin-6-one. Grade: > 95%. CAS No. 88110-89-8. Molecular formula: C11H15N5O5. Mole weight: 297.27. | |
| Ganciclovir Monopropionate | Ganciclovir Monopropionate is a potential prodrug of Ganciclovir. It was also found to exhibit anti-viral activity through experimental studies. Synonyms: Ganciclovir Mono-O-propionate; Ganciclovir Impurity B; 2-Amino-1,9-dihydro-9-[[1-(hydroxymethyl)-2-(1-oxopropoxy)ethoxy]methyl]-6H-purin-6-one. Grade: > 95%. CAS No. 194159-18-7. Molecular formula: C12H17N5O5. Mole weight: 311.30. | |
| Ganciclovir N,O-Diacetate | It is an impurity of Ganciclovir. Ganciclovir is an antiviral drug for feline herpesvirus type-1 with IC50 of 5.2 μM. Synonyms: Ganciclovir Impurity 13; 2-((2-acetamido-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy)-3-hydroxypropyl acetate. CAS No. 298197-26-9. Molecular formula: C13H17N5O6. Mole weight: 339.12. | |
| Ganciclovir Sodium | Ganciclovir Sodium is a potent inhibitor of the Herpesvirus family including cytomegalovirus. It is an acyclovir analog. It is used to treat complications from AIDS-associated cytomegalovirus infections. It was developed by Roche and has been listed. Uses: Ganciclovir sodium is used to treat complications from aids-associated cytomegalovirus infections. Synonyms: 2-Amino-1,9-dihydro-9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-6h-purin-6-one sodium salt; 9-[[1-(Hydroxymethyl)-2-hydroxyethoxy]methyl]-2-amino-9H-purine-6(1H)-one/sodium,(1:1) salt; Ganciclovir monosodium salt; 6H-Purin-6-one, 1,9-dihydro-2-amino-9-((2-hydroxy-1-(hydroxymethyl)ethoxy)methyl)-, monosodium salt; RS-21592 sodium; RS21592 Sodium; Sodium 2-amino-9-(1,3-dihydroxypropan-2-yloxymethyl)purin-6-olate. Grade: 98%. CAS No. 107910-75-8. Molecular formula: C9H12N5NaO4. Mole weight: 277.21. | |
| Ganciclovir Triphosphate | Ganciclovir Triphosphate, a nucleotide analogue possessing antiviral properties, is a prescribed medication for the management of CMV retinitis among individuals with immunodeficiency disease caused by human immunodeficiency virus (HIV). This nucleoside reverse transcriptase inhibitor subdues the activity of viral DNA polymerase and causes interference with viral DNA processing. Ganciclovir Triphosphate, a prodrug dependent on cellular kinases, undergoes conversion into its active metabolite, Ganciclovir Triphosphate. Uses: Antiviral agents. Synonyms: 9-(1,3-Dihydroxy-2-propoxymethyl)guanine-5'-Triphosphate; DHP-GTP; GCV-TP. Grade: ≥95% by AX-HPLC. CAS No. 86761-38-8. Molecular formula: C9H16N5O13P3. Mole weight: 495.20. | |
| Gancotamab | Gancotamab is an anti-HER2 antibody used in the research of HER2-positive breast cancer. Synonyms: MM-302; MM 302; MM302. Grade: 95%. CAS No. 1509928-00-0. | |
| Ganetespib | Ganetespib, also known as STA-9090, is a synthetic small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity. Hsp90 inhibitor STA-9090 binds to and inhibits Hsp90, resulting in the proteasomal degradation of oncogenic client proteins, the inhibition of cell proliferation and the elevation of heat shock protein 72 (Hsp72); it may inhibit the activity of multiple kinases, such as c-Kit, EGFR, and Bcr-Abl, which as client proteins depend on functional Hsp90 for maintenance. Hsp90, a 90 kDa molecular chaperone upregulated in a variety of tumor cells, plays a key role in the conformational maturation, stability and function of "client" proteins within the cell, many of which are involved in signal transduction, cell cycle regulation and apoptosis, including kinases, transcription factors and hormone receptors. Hsp72 exhibits anti-apoptotic functions; its up-regulation may be used as a surrogate marker for Hsp90 inhibition. Synonyms: STA-9090; STA 9090; STA9090. Grade: >98%. CAS No. 888216-25-9. Molecular formula: C20H20N4O3. Mole weight: 364.40. | |
| Ganglioside GD1a (Porcine Brain) | Ganglioside GD1a (Porcine Brain) is a remarkable bioactive lipid molecule used for studying neurodegeneration, specifically Alzheimer's and Parkinson's afflictions. Synonyms: Disialoganglioside-GD1a (porcine brain, diammonium salt); Ganglioside GD1a; Ganglioside B1; Ganglioside G3; Ganglioside GII; GD1a. Grade: >99%. CAS No. 12707-58-3. Molecular formula: C84H154N6O39. Mole weight: 1872.14. | |
| Ganglioside GD1b (Porcine Brain) diammonium salt | Ganglioside GD1b (Porcine Brain) Triammonium salt, a crucial glycosphingolipid, exerts vital influence over cell signaling and adhesion in the human body. Given its emerging therapeutic implications in treating neurological ailments like Parkinson's disease and multiple sclerosis, and certain cancers, it remains the focus of extensive studies. Meanwhile, its potential for modulating immune cell function in the realm of autoimmune disorders is compelling scientists to explore its promising attributes further. Synonyms: Ganglioside GD1b (porcine brain, triammonium salt); Octadecanamide, N-[(1S,2R,3E)-1-[[[O-(N-acetyl-α-neuraminosyl)-(2→8)-O-(N-acetyl-α-neuraminosyl)-(2→3)-O-[O-β-D-galactopyranosyl-(1→3)-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl-(1→4)]-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl]oxy]methyl]-2-hydroxy-3-heptadecen-1-yl]-, ammonium salt (1:2); N-[(1S,2R,3E)-1-[[[O-(N-Acetyl-α-neuraminosyl)-(2→8)-O-(N-acetyl-α-neuraminosyl)-(2→3)-O-[O-β-D-galactopyranosyl-(1→3)-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl-(1→4)]-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl]oxy]methyl]-2-hydroxy-3-heptadecen-1-yl]octadecanamide diammonium salt; Ganglioside GD1b (Porcine Brain) Triammonium salt. Grade: >99%. CAS No. 2315262-17-8. Molecular formula: C84H154N6O39. Mole weight: | |
| Ganglioside GD3 Disodium Salt | Ganglioside GD3 Disodium Salt is a ligand for human noroviruses. Synonyms: Disialosyllactosylceramide Disodium Salt; GD3 Disodium Salt; Ganglioside D3 Disodium Salt; Octadecanamide, N-[(1S,2R,3E)-1-[[[O-(N-acetyl-α-neuraminosyl)-(2→8)-O-(N-acetyl-α-neuraminosyl)-(2→3)-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl]oxy]methyl]-2-hydroxy-3-heptadecenyl]-, disodium salt; N-[(1S,2R,3E)-1-[[[O-(N-Acetyl-α-neuraminosyl)-(2→8)-O-(N-acetyl-α-neuraminosyl)-(2→3)-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl]oxy]methyl]-2-hydroxy-3-heptadecen-1-yl]octadecanamide disodium salt; Ganglioside GD3 (synthetic) disodium salt. CAS No. 497932-19-1. Molecular formula: C70H123N3Na2O29. Mole weight: 1516.71. | |
| Ganglioside GD3 Sodium Salt | Ganglioside GD3 Sodium Salt is related to Ganglioside GD3 Disodium Salt, which is a ligand for human noroviruses. Synonyms: Disialoganglioside GD3 sodium salt; Disialosyllactosylceramide Sodium Salt; GD3 Sodium Salt; Ganglioside D3 Sodium Salt; N-[(1S,2R,3E)-1-[[[O-(N-Acetyl-α-neuraminosyl)-(2→8)-O-(N-acetyl-α-neuraminosyl)-(2→3)-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl]oxy]methyl]-2-hydroxy-3-heptadecen-1-yl]-octadecanamide Sodium Salt (1:x); Ganglioside GD3 (synthetic) sodium salt. Grade: 95%. Molecular formula: C70H125N3O29.xNa. Mole weight: 1472.75 (free acid). | |
| Ganglioside GM1 | Ganglioside GM1 is a specific and only receptor for cholera toxin which facilitates the toxin's transmembrane movement. Cells which lack Ganglioside GM1 can be toxin-resistant, further proving the role of this receptor in the cholera toxicity mechanism. Synonyms: GM1 Ganglioside (Brain, Ovine-Sodium Salt); Ganglioside GM1; Ganglioside G4; Ganglioside A2; Ganglioside GGtet1; Ganglioside GI; Ganglioside GM1a; Ganglioside M1; GM1; GM1-Ganglioside; Monosialotetrahexosylganglioside; Sialosylganglio-N-tetraosylceramide; Sygen; Galβ1-3GalNAcβ1-4-[NeuAcα1-3]Galβ1-4Glcβ-Cer. Grade: >99%. CAS No. 37758-47-7. | |
| Ganglioside GQ1b (Porcine Brain) Tetraammonium salt | Ganglioside GQ1b (Porcine Brain) Tetraammonium salt is an essential biomolecule found in the porcine brain. This tetraammonium salt of Ganglioside GQ1b is used for studying various neurological disorders, known for its neuroprotective properties. Synonyms: Ganglioside GQ1b (porcine brain, tetraammonium salt); Octadecanamide, N-[(1S,2R,3E)-1-[[[O-(N-acetyl-α-neuraminosyl)-(2→8)-O-(N-acetyl-α-neuraminosyl)-(2→3)-O-β-D-galactopyranosyl-(1→3)-O-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl-(1→4)-O-[O-(N-acetyl-α-neuraminosyl)-(2→8)-N-acetyl-α-neuraminosyl-(2→3)]-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl]oxy]methyl]-2-hydroxy-3-heptadecen-1-yl]-, ammonium salt (1:4). Grade: >99%. CAS No. 2316360-46-8. Molecular formula: C106H194N10O55. Mole weight: 2488.73. | |
| Gangliosides | Gangliosides are glycosphingolipids predominantly located within the nervous system. These multifaceted compounds assume a pivotal role in facilitating intercellular exchange, governing neural growth and modulating synaptic adaptability. Synonyms: GM1, GD1a, GD1b, GT1b gangliosides, mixed ammoinum salts. | |
| Gangliotetraose | Gangliotetraose, a biomedicine product, stands as a pivotal remedy for ganglioside deficiency ailments, such as GM2-gangliosidosis and Tay-Sachs disease. Through emulating the constituents of gangliosides found naturally, it rejuvenates their abundance and ameliorates neuronal activity. Luringly, the tantalizing prospect of neuroprotection accompanies Gangliotetraose, holding great promise in its remedial capacity for those afflicted by these incapacitating disorders. Synonyms: Asialo-GM1-tetrasaccharide; Asialo GM1 oligosaccharide; O-β-D-Galactopyranosyl-(1→3)-O-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl-(1→4)-O-β-D-galactopyranosyl-(1→4)-D-glucose. CAS No. 75645-24-8. Molecular formula: C26H45NO21. Mole weight: 707.64. | |
| Gangliotriose | Gangliotriose is a crucial component utilized in the biomedical industry for researching various neurodegenerative diseases. Its structural similarities to gangliosides make it an ideal tool for studying drug targets associated with Alzheimer's disease, Parkinson's disease and other neurological disorders. Synonyms: Asialo-GM2-trisaccharide; N-Acetylgalactosamine b1-4 Lactose; Asialo GM2 oligosaccharide; GalNAc(b1-4)Gal(b1-4)Glc. CAS No. 1355005-58-1. Molecular formula: C20H35NO16. Mole weight: 545.49. | |
| Ganirelix | Ganirelix is a GnRH antagonist used primarily in assisted reproduction to control ovulation. It acts by blocking the action of GnRH upon the pituitary, thus rapidly suppressing the production and action of LH and FSH. Synonyms: D-Alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N6-[bis(ethylamino)methylene]-D-lysyl-L-leucyl-N6-[bis(ethylamino)methylene]-L-lysyl-L-prolyl-; N-Acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N6-[bis(ethylamino)methylene]-D-lysyl-L-leucyl-N6-[bis(ethylamino)methylene]-L-lysyl-L-prolyl-D-alaninamide; D 24598; Orgalutran; RS 26306; Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Tyr-D-hArg(Et,Et)-Leu-hArg(Et,Et)-Pro-D-Ala-NH2. Grade: 95%. CAS No. 124904-93-4. Molecular formula: C80H113ClN18O13. Mole weight: 1570.32. | |
| Ganirelix Impurity A | Ganirelix Impurity A. Grade: > 95%. Molecular formula: C67H102ClN17O12. Mole weight: 1373.12. | |
| Ganirelix Impurity B | Ganirelix Impurity B. Grade: > 95%. Molecular formula: C51H58ClN5O10. Mole weight: 936.51. | |
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