BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Ethynylestradiol Impurity 1 | An impurity of Estradiol. Estradiol? is the major estrogen secreted by the premenopausal ovary. Estrogens direct the development of the female genotype in embryogenesis and at puberty. Synonyms: (6R,13S,16S,17S)-16-ethynyl-3,6-dihydroxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-17-yl acetate. Grades: > 95%. Molecular formula: C22H26O4. Mole weight: 354.45. |  |
| Ethynylestradiol Impurity F | An impurity of Estradiol. Estradiol? is the major estrogen secreted by the premenopausal ovary. Estrogens direct the development of the female genotype in embryogenesis and at puberty. Synonyms: 6-beta-Hydroxy Ethynylestradiol. Grades: > 95%. CAS No. 56324-28-8. Molecular formula: C20H24O3. Mole weight: 312.41. | |
| Ethynylestradiol Impurity M | An impurity of Estradiol. Estradiol? is the major estrogen secreted by the premenopausal ovary. Estrogens direct the development of the female genotype in embryogenesis and at puberty. Synonyms: (8R,9S,13S,14S,17S)-3-cyanato-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-17-ol. Grades: > 95%. CAS No. 1818-11-7. Molecular formula: C21H24O2. Mole weight: 308.42. | |
| Etifoxine Metabolite | A metabolite of Etifoxine. Etifoxine is a positive allosteric modulator of GABA. Synonyms: 6-chloro-4-methyl-4-phenyl-1,4-dihydroquinazolin-2-ol. Grades: > 95%. Molecular formula: C15H13ClN2O. Mole weight: 272.74. | |
| Etilefrine Impurity D | An impurity of Etilefrin. Etilefrin is a sympathomimetic drug that increases the pulse rate, cardiac output, stroke volume, central venous pressure and mean arterial pressure of healthy individuals. Synonyms: 2-(benzyl(ethyl)amino)-1-(3-hydroxyphenyl)ethanone. Grades: > 95%. CAS No. 42146-10-1. Molecular formula: C17H19NO2. Mole weight: 269.35. | |
| Etilefrine Pivalate | Etilefrine Pivalate is an impurity of Etilefrine. Etilefrin is a sympathomimetic drug that increases the pulse rate, cardiac output, stroke volume, central venous pressure and mean arterial pressure of healthy individuals. Synonyms: [3-[2-(ethylamino)-1-hydroxyethyl]phenyl] 2,2-dimethylpropanoate. CAS No. 85750-39-6. Molecular formula: C15H23NO3. Mole weight: 265.353. | |
| Etodolac Impurity 1 | An impurity of Etodolac. Etodolac is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2. Synonyms: (Z)-dimethyl 3-ethyl-2-propionylpent-2-enedioate. Grades: > 95%. Molecular formula: C12H18O5. Mole weight: 242.27. | |
| Etodolac Impurity A | An impurity of Etodolac. Etodolac is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2. Synonyms: 8-Desethyl Etodolac. Grades: > 95%. CAS No. 41339-67-7. Molecular formula: C15H17NO3. Mole weight: 259.31. | |
| Etodolac Impurity B | An impurity of Etodolac. Etodolac is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2. Synonyms: 8-Methyl Etodolac; 1-Ethyl-1,3,4,9-tetrahydro-8-methylpyrano[3,4-b]indole-1-acetic Acid. Grades: > 95%. CAS No. 41340-19-6. Molecular formula: C16H19NO3. Mole weight: 273.33. | |
| Etodolac Impurity C | An impurity of Etodolac. Etodolac is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2. Synonyms: 2-(8-ethyl-1-methyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetic acid. Grades: > 95%. Molecular formula: C16H19NO3. Mole weight: 273.33. | |
| Etodolac Impurity I | An impurity of Etodolac. Etodolac is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2. Synonyms: 3-(7-ethyl-1H-indol-2-yl)-3-(7-ethyl-3-(2-hydroxyethyl)-1H-indol-2-yl)pentanoic acid. Grades: > 95%. Molecular formula: C27H32N2O3. Mole weight: 432.57. | |
| Etodolac Impurity J | An impurity of Etodolac. Etodolac is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2. Synonyms: Decarboxy Etodolac; 1,?8-Diethyl-1,?3,?4,?9-tetrahydro-1-methyl-pyrano[3,?4-b]?indole. Grades: > 95%. CAS No. 115066-03-0. Molecular formula: C16H21NO. Mole weight: 243.35. | |
| Etodolac Impurity K | An impurity of Etodolac. Etodolac is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2. Synonyms: 1,8-Diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indole-1-acetic Acid Methyl Ester. Grades: > 95%. CAS No. 122188-02-7. Molecular formula: C18H23NO3. Mole weight: 301.39. | |
| Etofenamate | Medication used to alleviate joint and muscle pain. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: TVX485; TVX-485; TVX 485; WHR-5020; WHR 5020; WHR5020; Etofenamate; Bay d 1107; Bayrogel; Rheumon. 2-[[3- (Trifluoromethyl) phenyl]amino]benzoic Acid 2-(2-Hydroxyethoxy)ethyl Ester; 2-(2-Hydroxyethoxy)ethyl Fufenamate; Bayrogel; Reumon; Rheumon; Traumon Gel. Grades: >98%. CAS No. 30544-47-9. Molecular formula: C18H18F3NO4. Mole weight: 369.34. | |
| Etofenamate O-Glucuronide | A derivative of Etofenamate. Etofenamate is a non-steroidal anti-inflammatory drug used for the treatment of joint and muscular pain. Synonyms: 2-[[3- (Trifluoromethyl) phenyl]amino]benzoic Acid 2-(2-Hydroxyethoxy)ethyl Ester O-β-D-Glucuronide; 2-(2-Hydroxyethoxy)ethyl Fufenamate O-β-D-Glucuronide. Grades: > 95%. Molecular formula: C24H27F3NO10. Mole weight: 546.48. | |
| Etomidate EP Impurity A | An impurity of Etomidate. Etomidate is a short-acting intravenous anaesthetic agent used for the induction of general anaesthesia and sedation for short procedures such as reduction of dislocated joints, tracheal intubation, and cardioversion. Synonyms: 1-(1-phenylethyl)-1H-imidazole-5-carboxylic acid. Grades: > 95%. CAS No. 3157-27-5. Molecular formula: C12H12N2O2. Mole weight: 216.24. | |
| Etomidate Impurity C HCl | An impurity of Etomidate. Etomidate is a short-acting intravenous anaesthetic agent used for the induction of general anaesthesia and sedation for short procedures such as reduction of dislocated joints, tracheal intubation, and cardioversion. Synonyms: (R)-isopropyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate HCl. Grades: > 95%. CAS No. 66512-39-8. Molecular formula: C15H18N2O2 HCl. Mole weight: 258.32 36.46. | |
| Etonogestrel | Etonogestrel is a synthetic form of progesterone. It is a medication which is used as a means of birth control for women. Uses: A impurity of desogestrel. Synonyms: Implanon; 3-Oxodesogestrel; nexplanon. Grades: ≥95%. CAS No. 54048-10-1. Molecular formula: C22H28O2. Mole weight: 324.5. | |
| Etoposide Hydroxy Acid | An impurity of Etoposide. Etoposide is a cytotoxic anticancer drug which belongs to the topoisomerase inhibitor drug class. It is used in form of its salt etoposide phosphate. Synonyms: Etoposide Hydroxy Acid (Mixture of Diastereomers). Grades: > 95%. Molecular formula: C29H34O14. Mole weight: 606.59. | |
| Etoricoxib Impurity AJ | An impurity of Etoricoxib. Etoricoxib is a selective COX-2 inhibitor. Grades: ≥95%. Molecular formula: C18H17N3O2S. Mole weight: 339.41. | |
| Etoricoxib Impurity QJ | An impurity of Etoricoxib. Etoricoxib is a selective COX-2 inhibitor. Grades: ≥95%. Molecular formula: C18H16N2O3S. Mole weight: 340.40. | |
| ETP-46321 | ETP-46321 is a potent and orally bioavailable PI3K α, δ inhibitor with potent biochemical and cellular activity and good pharmacokinetic properties (PK) after oral dosing. ETP-46321 PK/PD studies showed time dependent downregulation of AKT(Ser473) phosphorylation, which correlates with compound levels in tumor tissue and demonstrating to be efficacious in a GEMM mouse tumor model driven by a K-Ras(G12V) oncogenic mutation. Treatment with ETP-46321 resulted in significant tumor growth inhibition. Synonyms: ETP46321; ETP-46321; ETP 46321; 5-[2-[(4-methylsulfonylpiperazin-1-yl)methyl]-8-morpholin-4-ylimidazo[1,2-a]pyrazin-6-yl]pyrimidin-2-amine. Grades: >98%. CAS No. 1252594-99-2. Molecular formula: C20H27N9O3S. Mole weight: 473.556. | |
| Etravirine Impurity 1 | An impurity of Etravirine. Etravirine is a non-nucleoside reverse transcriptase inhibitor. Synonyms: 4-((4,6-dichloropyrimidin-2-yl)oxy)-3,5-dimethylbenzonitrile. Grades: > 95%. Molecular formula: C13H9Cl2N3O. Mole weight: 294.14. | |
| Etravirine Impurity 2 | An impurity of Etravirine. Etravirine is a non-nucleoside reverse transcriptase inhibitor. Synonyms: 4-((2-chloro-6-((4-cyanophenyl)amino)pyrimidin-4-yl)oxy)-3,5-dimethylbenzonitrile. Grades: > 95%. Molecular formula: C20H14ClN5O. Mole weight: 375.82. | |
| Etravirine Impurity 3 | An impurity of Etravirine. Etravirine is a non-nucleoside reverse transcriptase inhibitor. Synonyms: 4-((4-chloro-6-((4-cyanophenyl)amino)pyrimidin-2-yl)oxy)-3,5-dimethylbenzonitrile. Grades: > 95%. Molecular formula: C20H14ClN5O. Mole weight: 375.82. | |
| Etravirine Impurity 4 | An impurity of Etravirine. Etravirine is a non-nucleoside reverse transcriptase inhibitor. Synonyms: 4-((4-amino-6-((4-cyanophenyl)amino)pyrimidin-2-yl)oxy)-3,5-dimethylbenzonitrile. Grades: > 95%. Molecular formula: C20H16N6O. Mole weight: 356.39. | |
| Etravirine Impurity 5 | An impurity of Etravirine. Etravirine is a non-nucleoside reverse transcriptase inhibitor. Synonyms: 4-((4-amino-5-bromo-6-((4-cyanophenyl)amino)pyrimidin-2-yl)oxy)-3,5-dimethylbenzonitrile. Grades: > 95%. Molecular formula: C20H15BrN6O. Mole weight: 435.29. | |
| Etretinate | Etretinate is a second-generation retinoid to treat severe psoriasis. It has been replaced by acitretin, a safer metabolite of etretinate. Uses: Antipsoriatic. Synonyms: Tegison; Tigason; Ethyl etrinoate; HSDB 7185; HSDB7185; HSDB-7185; NSC 297936; NSC297936; NSC-297936; Ro 10-9359; Ro 10 9359; Ro109359; Acitretin Related Compound B USP. Grades: 98%. CAS No. 54350-48-0. Molecular formula: C23H30O3. Mole weight: 354.48. | |
| EUK 134 | EUK 134, a synthetic superoxide dismutase (SOD)/catalase mimetic, exhibits potent antioxidant activities, and inhibits the formation of β-amyloid and related amyloid fibril. Synonyms: Acetorphan; EUK-134; EUK134. Grades: >98%. CAS No. 81065-76-1. Molecular formula: C18H18ClMnN2O4. Mole weight: 416.74. | |
| Evacetrapib | Evacetrapib (LY2484595) is a drug that inhibits cholesterylester transfer protein, which transfers and thereby increases high-density lipoprotein and lowers low-density lipoprotein. Synonyms: LY2484595; LY 2484595; LY-2484595. Grades: 0.98. CAS No. 1186486-62-3. Molecular formula: C31H36F6N6O2. Mole weight: 638.659. | |
| Everolimus 27-O-Desmethyl Impurity | An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: 27-O-Desmethyl Everolimus. Grades: > 95%. Molecular formula: C52H81NO14. Mole weight: 944.22. | |
| Everolimus 28-Ethylhydroxy Impurity | An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: 28-Ethylhydroxy Rapamycin. Grades: > 95%. Molecular formula: C53H83NO14. Mole weight: 958.25. | |
| Everolimus, Cyclosporine and Tacrolimus Mix Standard | Everolimus is a derivative of Rapamycin. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Cyclosporine is an immunopsupressent thought to bind to cyclophilin in T-lymphocytes. Tacrolimus is also an immunosuppressant that blocks T-cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2. Shown to inhibit the activity of FK-506 binding protein, thereby reversing its effects on sarcoplasmic reticulum Ca+2 release. Molecular formula: C53H83NO14/C62H111N11O12/C44H69N. Mole weight: 958.22/1202.61/612.02. | |
| Everolimus Dehydrate Impurity | An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: Everolimus Dehydro Seco Acid. Grades: > 95%. Molecular formula: C53H83NO14. Mole weight: 958.25. | |
| Everolimus Hydrolized Impurity | An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: seco Everolimus B; (2S)-1-[2-[(2R, 3R, 6S)-6-[(2S, 3E, 5E, 7E, 9S, 11R, 13R, 14R, 15E, 17R, 20S, 21R)-14, 20-Dihydroxy-22-[(1S, 3R, 4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-2, 13-dimethoxy-3, 9, 11, 15, 17, 21-hexamethyl-12, 18-dioxo-3, 5, 7, 15-docosatetraen-1-yl]tetrahydro-. Grades: > 95%. CAS No. 769905-89-7. Molecular formula: C53H85NO15. Mole weight: 976.27. | |
| Everolimus Isomer C | An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: 9,14-Deepoxy-15-deoxo-14-deoxy-9,15-epoxy-15-hydroxy-42-O-(2-hydroxyethyl)-14-oxorapamycin. Grades: 80%. CAS No. 908340-97-6. Molecular formula: C53H83NO14. Mole weight: 958.25. | |
| Everolimus O-Desmethyl Impurity (Mixture of Diastereomers) | An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: 27-O-Desmethyl Everolimus. Grades: > 95%. Molecular formula: C52H81NO14. Mole weight: 944.22. | |
| Everolimus O-Ethyl Impurity | An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: 7-O-Desmethyl-7-O-ethyl Everolimus. Grades: > 95%. CAS No. 1704711-12-5. Molecular formula: C54H85NO14. Mole weight: 972.28. | |
| Everolimus O-Silyl Impurity | An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: 42-O-tert-Butyldimethylsilyloxyethyl Rapamycin; 42-O-[2-[[ (1, 1-Dimethylethyl) dimethylsilyl]oxy]ethyl]rapamycin. Grades: > 95%. CAS No. 159351-68-5. Molecular formula: C59H97NO14Si. Mole weight: 1072.52. | |
| Everolimus Related Compound 1 | An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: O-Desmethyl Everolimus. Grades: > 95%. CAS No. 745779-75-3. Molecular formula: C52H81NO14. Mole weight: 944.22. | |
| Everolimus Related Compound 3 | Everolimus Ring-Opening Impurity. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: (2S)-1-[[(2R,3R,6S)-6-[(2S,3E,5E,7E,9S,11R)-2,13-Dimethoxy-3,9,11-trimethyl-12-oxo-3,5,7-tridecatrienyl]tetrahydro-2-hydroxy-3-methyl-2H-pyran-2-yl]oxoacetyl]-2-piperidinecarboxylic Acid. Grades: 65%. CAS No. 147438-30-0. Molecular formula: C32H49NO9. Mole weight: 591.75. | |
| Everolimus Related Compound 4 | An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: (2S)-1-[2-[(2R, 3R, 6S)-6-[(2S, 3E, 5E, 7E, 9S, 11R, 13R, 14R, 15E, 17R, 20S, 21R)-14, 20-Dihydroxy-22-[(1S, 3R, 4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-2, 13-dimethoxy-3, 9, 11, 15, 17, 21-hexamethyl-12, 18-dioxo-3, 5, 7, 15-docosatetraen-1-yl]tetrahydro-2-hydroxy-3-methyl-. Grades: > 95%. Molecular formula: C57H91NO16. Mole weight: 1046.36. | |
| Everolimus Related Compound 5 | An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: Di-tert-butyl-4-methylene-2,5-cyclohexadienone; 2,6-Di-t-butyl-4-methylene-2,5-cyclohexadienone. Grades: > 95%. CAS No. 2607-52-5. Molecular formula: C15H22O. Mole weight: 218.34. | |
| Everolimus Ring-Opening Impurity | An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: Everolimus Retroaldol Degradation Product. Grades: > 95%. CAS No. 1708118-13-1. Molecular formula: C53H83NO14. Mole weight: 958.25. | |
| Evofosfamide | Evofosfamide is a hypoxia-activated prodrug consisting of a 2-nitroimidazole phosphoramidate conjugate with potential antineoplastic activity. The 2-nitroimidazole moiety of hypoxia-activated prodrug TH-302 acts as a hypoxic trigger, releasing the DNA-alkylating dibromo isophosphoramide mustard moiety within hypoxic regions of tumors. Normoxic tissues may be spared due to the hypoxia-specific activity of this agent, potentially reducing systemic toxicity. Synonyms: TH-302; TH 302; TH302; 2-bromo-N-[(2-bromoethylamino)-[(3-methyl-2-nitroimidazol-4-yl)methoxy]phosphoryl]ethanamine. Grades: > 98%. CAS No. 918633-87-1. Molecular formula: C9H16Br2N5O4P. Mole weight: 449.04. | |
| Evogliptin Tartrate | Evogliptin is an antidiabetic drug in the dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Synonyms: 2-Piperazinone, 4-[(3R)?-3-amino-1-oxo-4-(2,?4,?5-trifluorophenyl)?butyl]?-3-[(1,?1-dimethylethoxy)?methyl]?-, (3R)?-, (2R,?3R)?-2,?3-dihydroxybutanedioat?e (1:1). Grades: > 95%. CAS No. 1222102-51-3. Molecular formula: C19H26F3N3O3. C4H6O6. Mole weight: 401.43 150.09. | |
| Evogliptin Tartrate Impurity S1 | An isomer of Evogliptin. Evogliptin is an antidiabetic drug in the dipeptidyl peptidase-4 (DPP-6) inhibitor class of drugs. Synonyms: 2-Piperazinone, 4-[(3S)?-3-amino-1-oxo-4-(2,?4,?5-trifluorophenyl)?butyl]?-3-[(1,?1-dimethylethoxy)?methyl]?-, (3R)?-, (2R,?3R)?-2,?3-dihydroxybutanedioat?e (1:1). Grades: > 95%. Molecular formula: C19H26F3N3O3. C4H6O6. Mole weight: 401.43 150.09. | |
| Evogliptin Tartrate Impurity S2 | An isomer of Evogliptin. Evogliptin is an antidiabetic drug in the dipeptidyl peptidase-4 (DPP-5) inhibitor class of drugs. Synonyms: 2-Piperazinone, 4-[(3S)?-3-amino-1-oxo-4-(2,?4,?5-trifluorophenyl)?butyl]?-3-[(1,?1-dimethylethoxy)?methyl]?-, (3S)?-, (2R,?3R)?-2,?3-dihydroxybutanedioat?e (1:1). Grades: > 95%. Molecular formula: C19H26F3N3O3. C4H6O6. Mole weight: 401.43 150.09. | |
| Evogliptin Tartrate Impurity S3 | An isomer of Evogliptin. Evogliptin is an antidiabetic drug in the dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Synonyms: 2-Piperazinone, 4-[(3R)?-3-amino-1-oxo-4-(2,?4,?5-trifluorophenyl)?butyl]?-3-[(1,?1-dimethylethoxy)?methyl]?-, (3S)?-, (2R,?3R)?-2,?3-dihydroxybutanedioat?e (1:1). Grades: > 95%. Molecular formula: C19H26F3N3O3. C4H6O6. Mole weight: 401.43 150.09. | |
| Exemestane Impurity 1 | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 1,2-α-Epoxy Exemestane; (1α,2α)-1,2-Epoxy-6-methyleneandrost-4-ene-3,17-dione. Grades: > 95%. CAS No. 159354-61-7. Molecular formula: C20H24O3. Mole weight: 312.41. | |
| Exemestane Impurity 3 | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6,16-Dimethylideneandrosta-1,4-diene-3,17-dione. Grades: > 95%. Molecular formula: C21H24O2. Mole weight: 308.42. | |
| Exemestane Impurity 4 | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 16-methylideneandrosta-1,4-diene-3,17-dione. Grades: > 95%. Molecular formula: C20H24O2. Mole weight: 296.41. | |
| Exemestane Metabolite 1 | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 17β-Hydroxy Exemestane Sulfamate; (17β)-17-[(Aminosulfonyl)oxy]-6-methyleneandrosta-1,4-dien-3-one. Grades: > 95%. Molecular formula: C20H27NO4S. Mole weight: 377.51. | |
| Exemestane Metabolite 2 | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6-Hydroxy-6-(methoxymethyl)-androsta-1,4-diene-3,17-dione. Grades: > 95%. Molecular formula: C21H28O4. Mole weight: 344.45. | |
| Exemestane Related Compound | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6α-(Methoxymethyl)androsta-1,4-dien-3,17-dione. Grades: > 95%. CAS No. 881896-95-3. Molecular formula: C21H28O3. Mole weight: 328.46. | |
| Exemestane Related Compound 1 | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6β-(Formyl)androsta-1,4-dien-3,17-dione. Grades: > 95%. Molecular formula: C20H24O3. Mole weight: 312.41. | |
| Exemestane Related Compound 2 | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 17-hydroxy-8,10,13-trimethyl-3-oxo--decahydro-3H-cyclopenta[a]phenanthrene-6-carboxylic acid. Grades: > 95%. Molecular formula: C20H24O3. Mole weight: 312.41. | |
| Exemestane Related Compound 2 (17-alpha isomer) | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 17-alpha-hydroxy-8,10,13-trimethyl-3-oxo--decahydro-3H-cyclopenta[a]phenanthrene-6-carboxylic acid. Grades: > 95%. Molecular formula: C20H24O3. Mole weight: 312.41. | |
| Exemestane Related Compound 2 (17-beta isomer) | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 17-beta-hydroxy-8,10,13-trimethyl-3-oxo--decahydro-3H-cyclopenta[a]phenanthrene-6-carboxylic acid. Grades: > 95%. Molecular formula: C20H24O3. Mole weight: 312.41. | |
| Exemestane Related Compound A | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 1,2-Dihydro Exemestane; 6-Methyleneandrost-4-ene-3,17-dione; 6-Methyleneandrost-4-en-3,17-dione. Grades: > 95%. CAS No. 19457-55-7. Molecular formula: C20H26O2. Mole weight: 298.43. | |
| Exemestane Related Compound B | Isotope labelled Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: Androsta-1,4-diene-3,17-dione, 6-(hydroxymethyl). Grades: > 95%. CAS No. 184972-09-6. Molecular formula: C20H26O3. Mole weight: 314.43. | |
| Exendin 3 (9-39) | Exendin (9-39) is a specific and competitive glucagon-like peptide-1receptor antagonist (Kd = 1.7 nM at cloned human GLP-1 receptors). Exendin (9-39) inhibits insulin release and cAMP production caused by GLP-1 (7-36), exendin-3, and exendin-4. Synonyms: Exendin 9-39; Exendin 9 39; H-DL-Asp-DL-Leu-DL-Ser-DL-Lys-DL-Gln-DL-Met-DL-Glu-DL-Glu-DL-Glu-DL-Ala-DL-Val-DL-Arg-DL-Leu-DL-Phe-DL-xiIle-DL-Glu-DL-Trp-DL-Leu-DL-Lys-DL-Asn-Gly-Gly-DL-Pro-DL-Ser-DL-Ser-Gly-DL-Ala-DL-Pro-DL-Pro-DL-Pro-DL-Ser-NH2; DL-alpha-aspartyl-DL-leucyl-DL-seryl-DL-lysyl-DL-glutaminyl-DL-methionyl-DL-alpha-glutamyl-DL-alpha-glutamyl-DL-alpha-glutamyl-DL-alanyl-DL-valyl-DL-arginyl-DL-leucyl-DL-phenylalanyl-DL-isoleucyl-DL-alpha-glutamyl-DL-tryptophyl-DL-leucyl-DL-lysyl-DL-asparagyl-glycyl-glycyl-DL-prolyl-DL-seryl-DL-seryl-glycyl-DL-alanyl-DL-prolyl-DL-prolyl-DL-prolyl-DL-serinamide. Grades: ≥95%. CAS No. 133514-43-9. Molecular formula: C149H234N40O47S. Mole weight: 3369.76. | |
| Exherin | Exherin, also known as ADH-1, is a small, cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities. ADH-1 selectively and competitively binds to and blocks N-cadherin, which may result in disruption of tumor vasculature, inhibition of tumor cell growth, and the induction of tumor cell and endothelial cell apoptosis. N-cadherin, a cell- surface transmembrane glycoprotein of the cadherin superfamily of proteins involved in calcium-mediated cell-cell adhesion and signaling mechanisms; may be upregulated in some aggressive tumors and the endothelial cells and pericytes of some tumor blood vessels. Synonyms: NSC729477; ADH-1; NSC7 29477; ADH 1; NSC-729477; ADH1. Grades: 98%. CAS No. 229971-81-7. Molecular formula: C22H34N8O6S2. Mole weight: 570.69. | |
| exo-Tropine-3-thiol Hydrochloride | exo-Tropine-3-thiol Hydrochloride is used in the synthesis of Retapamulin, which is a topical antibiotic used for the topical treatment of impetigo caused by Staphylococcus aureus (methicillin-susceptible only) or Streptococcus pyogenes. Synonyms: 8-Azabicyclo[3.2.1]octane-3-thiol, 8-methyl-, hydrochloride (1:1), (3-exo)-; (3-exo)-8-Methyl-8-azabicyclo[3.2.1]octane-3-thiol hydrochloride (1:1). CAS No. 1141886-66-9. Molecular formula: C8H15NS.HCl. Mole weight: 193.74. | |
| Ezatiostat | Ezatiostat is a glutathione analog that acts as an inhibitor of glutathione S-transferase (GST) P1-1. TLK117, the active form of ezatiostat, inhibits GSTP1-1, resulting in phosphorylation of JNK, restoring JNK-mediated cellular proliferation and differentiation signaling pathways. Synonyms: Telintra; Gamma-Glu-S-BzCys-PhGly diethyl ester; TLK-199; TLK 199. CAS No. 168682-53-9. Molecular formula: C27H35N3O6S. Mole weight: 529.652. | |
| E,Z-cis-3-(2-Chloroethenyl)-2,2-dimethyl-cyclopropanecarboxylic Acid | Cas No. 106974-78-1. | |
| (E/Z)-Endoxifen | One of the impurities of Tamoxifen, which is an estrogen response modifier as well as protein kinase C inhibitor. Synonyms: 4-Hydroxy-N-Desmethyl Tamoxifen; N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture); 4-[1-[4-[2-(Methylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenol. Grades: > 95%. CAS No. 110025-28-0. Molecular formula: C25H27NO2. Mole weight: 373.50. | |
| E,Z-trans-3-(2-Chloroethenyl)-2,2-dimethyl-cyclopropanecarboxylic Acid | E,Z-trans-3-(2-Chloroethenyl)-2,2-dimethyl-cyclopropanecarboxylic Acid is the photolysis product of Permethrin, which is a medication and an insecticide used to treat scabies and lice. Synonyms: E,Z-trans-3-(2-Chlorovinyl)-2,2-dimethylcyclopropanecarboxylic Acid; Cyclopropanecarboxylic acid, 3-[(1E)-2-chloroethenyl]-2,2-dimethyl-, (1R,3S)-rel-; rel-(1R,3S)-3-((E)-2-chlorovinyl)-2,2-dimethylcyclopropane-1-carboxylic acid; Cyclopropanecarboxylic acid, 3-(2-chloroethenyl)-2,2-dimethyl-, [1α,3β(E)]-. Grades: 98%. CAS No. 61914-45-2. Molecular formula: C8H11ClO2. Mole weight: 174.62. | |
| Famciclovir Impurity 8 | An impurity of Famciclovir. Famciclovir is used for the treatment of various herpesvirus infections, most commonly for herpes zoster. Synonyms: 9-(4-Acetoxy-2-acetoxymethyl-but-1-yl)-2-aminopurine. Grades: > 95%. CAS No. 126589-69-3. Molecular formula: C14H19N5O4. Mole weight: 321.34. | |
| Famciclovir N7-Isomer | An impurity of Famciclovir. Famciclovir is used for the treatment of various herpesvirus infections, most commonly for herpes zoster. Synonyms: 2-[2-(2-Amino-7H-purin-7-yl)ethyl]-1,3-propanediol 1,3-Diacetate. Grades: > 95%. CAS No. 131266-15-4. Molecular formula: C14H19N5O4. Mole weight: 321.34. | |
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