BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Fumaric Acid tert-Butyl Ester | Fumaric Acid tert-Butyl Ester is a tert-butyl ester derivative of Fumaric acid, which is a drug used to treat the autoimmune condition psoriasis. It is also used as a food additive. Synonyms: (2E)-2-Butenedioic Acid Mono(1,1-dimethylethyl) Ester; (E)-4-tert-Butoxy-4-oxobut-2-enoic Acid; Fumaric acid mono-tert-butyl ester; (E)-4-(Tert-butoxy)-4-oxobut-2-enoic acid; 2-Butenedioic acid, mono(1,1-dimethylethyl)ester, (2E)-. Grade: 95%. CAS No. 135355-96-3. Molecular formula: C8H12O4. Mole weight: 172.18. |  |
| Funapide | Funapide is a Nav1.7 and Nav1.8 voltage-gated sodium channel inhibitor under the development by Xenon Pharmaceuticals and Teva Pharmaceutical Industries. It is applicated for the treatment of a variety of chronic painconditions, including osteoarthritis, neuropathic pain, postherpetic, neuralgia, erythromelalgia and dental pain. In July 2014, Funapide has reached phase IIb clinical trials. Uses: Chronic painconditions. Synonyms: UNII-A5595LHJ2L; A5595LHJ2L; XEN-401-S; TV-45070; TV 45070; TV45070; XEN402; XEN-402; XEN 402; Funapide.(7S)-1'-[[5-(trifluoromethyl)furan-2-yl]methyl]spiro[6H-furo[2,3-f][1,3]benzodioxole-7,3'-indole]-2'-one. Grade: 98%. CAS No. 1259933-16-8. Molecular formula: C22H14F3NO5. Mole weight: 429.35. | |
| Fungicide 4 | Fungicide 4 has the high activity against the P. infestans strain. Synonyms: Benzamide, N-1H-benzimidazol-2-yl-; N-(1H-1,3-benzodiazol-2-yl)benzamide; 2-benzoylaminobenzimidazole; N-(1H-benzo[d]imidazol-2-yl)benzamide; N-benzimidazol-2-ylbenzamide. CAS No. 7412-5-7. Molecular formula: C14H11N3O. Mole weight: 237.26. | |
| Fungicide 5 | Fungicide 5 is a fungicide candidate targeting succinate dehydrogenase (Ki = 0.095 μM). Synonyms: 1H-Pyrazole-4-carboxamide, N-[2-[2,4-bis(trifluoromethyl)phenoxy]phenyl]-3-(difluoromethyl)-1-methyl-; N-(2-(2,4-bis(trifluoromethyl)phenoxy)phenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide. CAS No. 2344721-61-3. Molecular formula: C20H13F8N3O2. Mole weight: 479.32. | |
| Furafylline | Furafylline is a xanthine derivative and a selective inhibitor of human cytochrome P450 (CYP)1A2 with an IC50 of 0.07 μM. It was reported to inhibit the oxidation of caffeine. Synonyms: 3-(2-furanylmethyl)-3,9-dihydro-1,8-dimethyl-1H-purine-2,6-dione; 3-Furfuryl-1,8-dimethylxanthine; 3-(furan-2-ylmethyl)-1,8-dimethyl-1H-purine-2,6(3H,7H)-dione; 1,8-dimethyl-3-(2'-furfuryl)-1H-purine-2,6-dione; Furafilina; Furafyllinum. Grade: 95%. CAS No. 80288-49-9. Molecular formula: C12H12N4O3. Mole weight: 260.25. | |
| Furagin | Furagin (a nitrofurantoin analog) has the same efficacy in treating acute cystitis as Ciprofloxacin, however the duration of therapy is longer. Antibacterial. Synonyms: NF 416; NF416; NF-416; F-35; Akritoin; Furazidin; Furazidine; Furagin. Grade: >98%. CAS No. 1672-88-4. Molecular formula: C10H8N4O5. Mole weight: 264.19. | |
| Furalazine | Furalazine is an antibiotic agent with activity against drug-resistant strains of cholera bacteria. It was more effective in reducing the duration of positive stool culture than chloramphenicol. It may be potentially used in the treatment of cholera. Uses: Furalazine is an antibiotic agent with activity against drug-resistant strains of cholera bacteria. it may be potentially used in the treatment of cholera. Synonyms: Furalazinum; Nifuralazinum; Panfuran; 3-Amino-6-(2-(5-nitro-2-furyl)vinyl)-1,2,4-triazine; 1,2,4-Triazin-3-amine, 6-(2-(5-nitro-2-furanyl)ethenyl)- (9CI). Grade: 98%. CAS No. 556-12-7. Molecular formula: C9H7N5O3. Mole weight: 233.18. | |
| Furaltadone | Furaltadone is a derivative of nitrofuran and has bactericidal activity against both gram-positive and gram-negative bacteria. Furaltadone is inhibitory and bactericidal in vitro for staphylococci. Uses: Anti-infective agents, urinary. Synonyms: Nitrofurmethone; Nitrofurmeton; Furazolin; Furmethanol; Medifuran. Grade: Purity >98%. CAS No. 139-91-3. Molecular formula: C13H16N4O6. Mole weight: 324.29. | |
| Furaltadone Hydrochloride | Furaltadone HCl is an antibacterial and has distinct curative effect in the treatment of coccidiosis. Grade: >98%. CAS No. 3759-92-0. Molecular formula: C13H16N4O6.HCl. Mole weight: 360.75. | |
| Furaltadone L-tartrate | Furaltadone L-tartrate has the potential for the study in infections of chickens with salmonella enteritidis. Furaltadone is inhibitory and bactericidal in vitro for staphylococci. Synonyms: Altafur L-tartrate; 2,3-Dihydroxybutanedioic acid-5-[(morpholin-4-yl)methyl]-3-{[(5-nitrofuran-2-yl)methylidene]amino}-1,3-oxazolidin-2-one (1/1). CAS No. 14343-71-6. Molecular formula: C17H22N4O12. Mole weight: 474.38. | |
| Furamidine | Furamidine is a protein arginine methyltransferase 1 (PRMT1) inhibitor (IC50 = 9.4 μM) in the class of antimicrobial and antiparasitic agent. It was shown to inhibit cell proliferation in leukemia cell lines. Synonyms: Benzenecarboximidamide, 4,4'-(2,5-furandiyl)bis-; NSC-305831; BRN 1435532; DB 75; DB75; DB-75. CAS No. 73819-26-8. Molecular formula: C18H16N4O. Mole weight: 304.35. | |
| Furamidine dihydrochloride | Furamidine dihydrochloride is a protein arginine methyltransferase 1 (PRMT1) inhibitor (IC50 = 9.4 μM) in the class of antimicrobial and antiparasitic agents. It was shown to inhibit cell proliferation in leukemia cell lines. Synonyms: 4,4'-(2,5-Furandiyl)bis-benzenecarboximidamide dihydrochloride. Grade: ≥98% by HPLC. CAS No. 55368-40-6. Molecular formula: C18H16N4O.2HCl. Mole weight: 377.27. | |
| Furaneol glucopyranoside | Furaneol glucopyranoside is a remarkable bioactive compound extensively utilized in the biomedical sector, applied to study diabetes and its related complications. This compound exhibits profound efficacy in the regulation of blood sugar levels and the mitigation of oxidative stress. Synonyms: 2,5-Dimethyl-4-hydroxy-3(2H)-furanone 6O-malonyl-beta-D-glucopyranoside; HDMF glucoside. Molecular formula: C12H18O8. Mole weight: 290.27. | |
| Furanone C-30 | Furanone C-30 is a synthetic furanone bacterial quorum sensing inhibitor that inhibits virulence factor expression in Pseudomonas aeruginosa and increases bacterial susceptibility to antibiotics in vitro. Synonyms: (5Z)-4-Bromo-5-(bromomethylene)-2(5H)-furanone. Grade: ≥98%. CAS No. 247167-54-0. Molecular formula: C5H2Br2O2. Mole weight: 253.88. | |
| Furazlocillin | Fuzlocillin is a semisynthetic acylureidopenicillin with antibacterial activity. It binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall, thus preventing the cross-linkage of peptidoglycans, which leads to an interruption of the bacterial cell wall and causes bacterial cell lysis. Uses: Fuzlocillin has antibacterial activity. Synonyms: 6α-[[(R)-[[[3-[[(E)-(2-Furanyl)methylene]amino]-2-oxoimidazolidin-1-yl]carbonyl]amino](4-hydroxyphenyl)acetyl]amino]penicillanic acid; BAY-k-4999. Grade: 98%. CAS No. 66327-51-3. Molecular formula: C25H26N6O8S. Mole weight: 570.58. | |
| Furcatin | A substrate of Furcatin Hydrolase (FH). This enzyme catalyzes the hydrolysis of Furcatin producing p-Allylphenol and the disaccharide Acuminose. Uses: Substrate of furcatin hydrolase (fh). this enzyme catalyzes the hydrolysis of furcatin producing p-allylphenol and the disaccharide acuminose. Synonyms: 4-(2-Propen-1-yl)phenyl 6-O-D-Apio-β-D-furanosyl-β-D-glucopyranoside; p-Allylphenyl 6-O-β-D-apiofuranosyl-β-D-glucopyranoside. CAS No. 499-33-2. Molecular formula: C20H28O10. Mole weight: 428.43. | |
| Furcellaran | Furcellaran is a remarkable biomedical product, sourced from the majestic red seaweed, exhibiting potent antiviral attributes. Furcellaran is a κ-carrageenan-like gum from Furcellaria fastigiata. Synonyms: Danish agar; Estagar; Furcellaria gum; Furtselleran; Gel Up J 1915; Inagel EF 350. CAS No. 9000-21-9. | |
| Furegrelate | Furegrelate is a potent, orally available, and selective thromboxane synthase inhibitor. Furegrelate inhibits human platelet microsomal thromboxane A2 (TxA2) synthase with an IC50 of 15 nM. Furegrelate is being developed as an antiplatelet agent. Uses: Enzyme inhibitors. Synonyms: 5-(pyridin-3-ylmethyl)benzofuran-2-carboxylic acid; 2-Benzofurancarboxylic acid, 5-(3-pyridinylmethyl)-; U-63557A free acid. CAS No. 85666-24-6. Molecular formula: C15H11NO3. Mole weight: 253.25. | |
| Furegrelate sodium salt | Furegrelate is a selective and potent inhibitor of thromboxane synthase with an IC50 value of 15 nM for human platelet microsomal thromboxane synthase. Synonyms: U-63557A; 5-(3-pyridinylmethyl)-2-benzofurancarboxylic acid, sodium salt. Grade: ≥99%. CAS No. 85666-17-7. Molecular formula: C15H10NO3·Na. Mole weight: 275.2. | |
| Furfural-[3,4,5-d3] | Furfural-[3,4,5-d3]. Synonyms: Furfural-3,4,5-d3; d3-furfural. Grade: 98% atom D. CAS No. 53599-40-9. Molecular formula: C5HD3O2. Mole weight: 99.1. | |
| Furilazole | Furilazole, an oxazole derivative, is a herbicide commonly used for gramineous crops. Uses: Furilazole is a herbicide commonly used for gramineous crops. Synonyms: (RS)-3-Dichloroacetyl-5-(2-furanyl)-2,2-dimethyl-1,3-oxazolidine. Grade: 98%. CAS No. 121776-33-8. Molecular formula: C11H13Cl2NO3. Mole weight: 278.13. | |
| Furoentecavir | An impurity of Entecavir. Entecavir is a reverse transcriptase inhibitor. It prevents the hepatitis B virus from multiplying and reduces the amount of virus in the body. Synonyms: 2-amino-9-((3aS,4R,6S,6aR)-3a,6-dihydroxyhexahydro-1H-cyclopenta[c]furan-4-yl)-3H-purin-6(9H)-one. Grade: > 95%. CAS No. 1984788-96-6. Molecular formula: C12H15N5O4. Mole weight: 293.28. | |
| Furosemide acyl glucuronide | Furosemide acyl glucuronide is a metabolite of Furosemide. Synonyms: (2S,3S,4S,5R)-6-[4-Chloro-2-(2-Furylmethylamino)-5-Sulfamoyl-Benzoyl]Oxy-3,4,5-Trihydroxy-Tetrahydropyran-2-Carboxylic Acid; (2S,3S,4S,5R)-6-[[4-Chloro-2-(2-Furylmethylamino)-5-Sulfamoylphenyl]-Oxomethoxy]-3,4,5-Trihydroxy-2-Tetrahydropyrancarboxylic Acid. Grade: > 95%. CAS No. 72967-59-0. Molecular formula: C18H19ClN2O11S. Mole weight: 506.87. | |
| Furosemide Amide Impurity | An impurity of Furosemide. Furosemide is a potent loop diuretic used primarily to treat conditions involving fluid retention (edema) and high blood pressure. Synonyms: 5-(Aminosulfonyl)-4-chloro-2-[(2-furanylmethyl)amino]benzamide; 4-Chloro-2-(furfurylamino)-5-sulfamoylbenzamide; 4-Chloro-2-{[(furan-2-yl)methyl]amino}-5-sulfamoylbenzamide; Furosemide Amide. Grade: ≥95%. CAS No. 4793-47-9. Molecular formula: C12H12ClN3O4S. Mole weight: 329.76. | |
| Furosemide EP Impurity A | Furosemide EP Impurity A is an impurity of Furosemide. Furosemide is a medication used to treat fluid build-up and swelling caused by congestive heart failure, liver cirrhosis, or kidney disease. Synonyms: Furosemide Related Compound A; Iso Furosemide; 2-Chloro-4-(furfurylaMino)-5-sulfaMoylbenzoic Acid; Isolasix; 5-(Aminosulfonyl)-2-chloro-4-[(2-furanylmethyl)amino]benzoic Acid; H 20. Grade: > 95%. CAS No. 4818-59-1. Molecular formula: C12H11ClN2O5S. Mole weight: 330.75. | |
| Furosemide EP Impurity B | Furosemide EP Impurity B is an impurity of Furosemide. Furosemide is a medication used to treat fluid build-up and swelling caused by congestive heart failure, liver cirrhosis, or kidney disease. Synonyms: 2,4-Dichloro-5-aminosulfonylbenzoic acid; 3-Sulfamoyl-4,6-dichlorobenzoic acid; 5-Aminosulfonyl-2,4-dichlorobenzoic acid; 5-Carboxy-2,4-dichlorobenzenesulfonamide. Grade: > 95%. CAS No. 2736-23-4. Molecular formula: C7H5Cl2NO4S. Mole weight: 270.09. | |
| Furosemide EP Impurity C | Furosemide Impurity C is a metabolite of Furosemide. Furosemide is a medication used to treat fluid build-up and swelling caused by congestive heart failure, liver cirrhosis, or kidney disease. Synonyms: Furosemide Related Compound B; 4-Chloro-5-sulfamoylanthranilic acid; 4-Chloro-5-sulfamylanthranilic acid; Desfurylmethylfurosemide; Saluamine; 4-Chloro-5-sulfamoyl-anthranilic Acid. Grade: > 95%. CAS No. 3086-91-7. Molecular formula: C7H7ClN2O4S. Mole weight: 250.66. | |
| Furosemide EP Impurity D | Furosemide Impurity D is a Furosemide impurity. Furosemide is a medication used to treat fluid build-up and swelling caused by congestive heart failure, liver cirrhosis, or kidney disease. Synonyms: 4-Deschloro-4-(2-furanylmethyl)amino Furosemide; 5-(Aminosulfonyl)-2,4-bis[(2-furanylmethyl)amino]benzoic Acid. Grade: > 95%. CAS No. 5046-19-5. Molecular formula: C17H17N3O6S. Mole weight: 391.41. | |
| Furosemide EP Impurity F | Furosemide EP Impurity F is an impurity of Furosemide. Furosemide is a medication used to treat fluid build-up and swelling caused by congestive heart failure, liver cirrhosis, or kidney disease. Synonyms: Tetrahydro Furosemide; 4-Chloro-5-sulfamoyl-N-(tetrahydrofurfuryl)anthranilic Acid; 4-Chloro-5-Sulfamoyl-2-[[((2RS)-Tetrahydrofuran-2-yl)methyl]amino]Benzoic Acid. Grade: > 95%. CAS No. 4793-38-8. Molecular formula: C12H15ClN2O5S. Mole weight: 334.78. | |
| Furprofen | Furprofen is a non-steroidal anti-inflammatory drug (NSAID). Furprofen acts via the inhibition of prostaglandin (PGE) synthesis. Synonyms: 4-(2-Furanylcarbonyl)-alpha-methylbenzeneacetic acid; 2-[4-(2-Furoyl)phenyl]propionic acid. CAS No. 66318-17-0. Molecular formula: C14H12O4. Mole weight: 244.24. | |
| Fusariumester A1 | Fusariumester A1 is a compelling antifungal compound, showcasing robust inhibitory prowess against fungal pathogens, specifically hailing from the esteemed genus Fusarium. Molecular formula: C36H58O11. Mole weight: 666.84. | |
| Fusariumester A2 | Fusariumester A2 is a compelling fungicidal compound originating from the Fusarium fungus. Its modus operandi encompasses the disruption of fungal cellular barriers, culminating in their demise. Molecular formula: C36H58O11. Mole weight: 666.84. | |
| Fusidic acid acyl glucuronide | Fusidic acid acyl glucuronide is a metabolite originating from fusidic acid, acting as an efficacious antimicrobial compound employed for studying diverse bacterial ailments. It manifestly demonstrates amplified pharmacokinetic attributes encompassing heightened bioavailability and metabolic steadfastness. Synonyms: Fusidic acid, β-D-glucopyranuronosyl ester; 29-Nordammara-17(20),24-dien-21-oic acid, 16-(acetyloxy)-3,11-dihydroxy-, β-D-glucopyranuronosyl ester, (3α,4α,8α,9β,11α,13α,14β,16β,17Z)-; Fusidic Acid Acyl β-D-Glucuronide; (2S,3S,4S,5R,6S)-6-(((Z)-2-((3R,4S,5S,8S,9S,10S,11R,13R,14S,16S)-16-Acetoxy-3,11-dihydroxy-4,8,10,14-tetramethylhexadecahydro-17H-cyclopenta[a]phenanthren-17-ylidene)-6-methylhept-5-enoyl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid. Grade: ≥95%. CAS No. 13013-66-6. Molecular formula: C37H56O12. Mole weight: 692.83. | |
| Fusidic Acid EP Impurity A | An impurity of Fusidic acid, which is a steroidal antibiotic belonging to the fusidane class, derived from Fusidium coccineum. Fusidic acid is primarily effective against Gram-positive bacteria, including Staphylococcus aureus (particularly methicillin-resistant strains, MRSA). It is used to treat skin and soft tissue infections. Synonyms: ent-(24SR,17Z)-16α-(Acetyloxy)-3β,11β,24,25-tetrahydroxy-4β,8,14-trimethyl-18-nor-5β,10αcholest-17(20)-en-21-oic acid; 24,25-Dihydro-24,25-dihydroxyfusidic acid; Fusidic Acid Impurity A; Sodium Fusidate EP Impurity A. Grade: ≥95%. Molecular formula: C31H50O8. Mole weight: 550.73. | |
| Fusidic Acid EP Impurity B | An impurity of Fusidic acid, which is a steroidal antibiotic belonging to the fusidane class, derived from Fusidium coccineum. Fusidic acid is primarily effective against Gram-positive bacteria, including Staphylococcus aureus (particularly methicillin-resistant strains, MRSA). It is used to treat skin and soft tissue infections. Synonyms: ent-(17Z)-3β,11β-Dihydroxy-17-[(6SR)-6-hydroxy-7,7-dimethyl-2-oxooxepan-3-ylidene]-4β,8,14-trimethyl-18-nor-5β,10α-androstan-16α-yl acetate; 24,25-Dihydro-24,25-dihydroxyfusidic acid 21,25-lactone; Fusidic Acid Impurity B; Sodium Fusidate EP Impurity B; (3R,4S,5S,8S,9S,10S,11R,13R,14S,16S,Z)-3,11-dihydroxy-17-((SR)-6-hydroxy-7,7-dimethyl-2-oxooxepan-3-ylidene)-4,8,10,14-tetramethylhexadecahydro-1H-cyclopenta[a]phenanthren-16-yl acetate. Grade: ≥95%. Molecular formula: C31H48O7. Mole weight: 532.72. | |
| Fusidic Acid EP Impurity C | An impurity of Fusidic acid, which is a steroidal antibiotic belonging to the fusidane class, derived from Fusidium coccineum. Fusidic acid is primarily effective against Gram-positive bacteria, including Staphylococcus aureus (particularly methicillin-resistant strains, MRSA). It is used to treat skin and soft tissue infections. Synonyms: ent-(17Z)-3β,11β-Dihydroxy-17-[(6S)-6-(1-hydroxy-1-methylethyl)-2-oxodihydro-2H-pyran-3(4H)-ylidene]-4β,8,14-trimethyl-18-nor-5β,10α-androstan-16α-yl acetate; (24R)-24,25-Dihydro-24,25-dihydroxyfusidic acid 21,24-lactone; Fusidic Acid Impurity C; (3R,4S,5S,8S,9S,10S,11R,13R,14S,16S,Z)-3,11-Dihydroxy-17-((R)-6-(2-hydroxypropan-2-yl)-2-oxodihydro-2H-pyran-3(4H)-ylidene)-4,8,10,14-tetramethylhexadecahydro-1H-cyclopenta[a]phenanthren-16-yl acetate; Sodium Fusidate EP Impurity C. Grade: ≥95%. CAS No. 3054708-75-4. Molecular formula: C31H48O7. Mole weight: 532.72. | |
| Fusidic Acid EP Impurity D | An impurity of Fusidic acid, which is a steroidal antibiotic belonging to the fusidane class, derived from Fusidium coccineum. Fusidic acid is primarily effective against Gram-positive bacteria, including Staphylococcus aureus (particularly methicillin-resistant strains, MRSA). It is used to treat skin and soft tissue infections. Synonyms: ent-(17Z)-3β,11β-Dihydroxy-17-[(6R)-6-(1-hydroxy-1-methylethyl)-2-oxodihydro-2H-pyran-3(4H)-ylidene]-4β,8,14-trimethyl-18-nor-5β,10α-androstan-16α-yl acetate; (24S)-24,25-Dihydro-24,25-dihydroxyfusidic acid 21,24-lactone; Fusidic Acid Impurity D; (3R,4S,5S,8S,9S,10S,11R,13R,14S,16S,Z)-3,11-Dihydroxy-17-((S)-6-(2-hydroxypropan-2-yl)-2-oxodihydro-2H-pyran-3(4H)-ylidene)-4,8,10,14-tetramethylhexadecahydro-1H-cyclopenta[a]phenanthren-16-yl acetate; Sodium Fusidate EP Impurity D. Grade: ≥95%. CAS No. 3054708-76-5. Molecular formula: C31H48O7. Mole weight: 532.72. | |
| Fusidic Acid EP Impurity E | An impurity of Fusidic acid, which is a steroidal antibiotic belonging to the fusidane class, derived from Fusidium coccineum. Fusidic acid is primarily effective against Gram-positive bacteria, including Staphylococcus aureus (particularly methicillin-resistant strains, MRSA). It is used to treat skin and soft tissue infections. Synonyms: ent-(17Z,24EZ)-16α-(Acetyloxy)-3β,11β,26-trihydroxy-4β,8,14-trimethyl-18-nor-5β,10α-cholesta-17(20),24-dien-21-oic acid; 26-Hydroxyfusidic acid; Sodium Fusidate EP Impurity E; Fusidic Acid Impurity E; (3α,4α,5α,11α,16β,17Z)-16-(Acetyloxy)-3,11,26-trihydroxy-4,8,14-trimethyl-18-norcholesta-17(20),24-dien-21-oic acid; 26-Hydroxy Fusidic Acid; (2Z)-2-((3R,4S,5S,8S,9S,10S,11R,13R,14S,16S)-16-Acetoxy-3,11-dihydroxy-4,8,10,14-tetramethylhexadecahydro-17H-cyclopenta[a]phenanthren-17-ylidene)-7-hydroxy-6-methylhept-5-enoic acid. Grade: ≥95%. CAS No. 2802408-15-5. Molecular formula: C31H48O7. Mole weight: 532.71. | |
| Fusidic Acid EP Impurity F | An impurity of Fusidic acid, which is a steroidal antibiotic belonging to the fusidane class, derived from Fusidium coccineum. Fusidic acid is primarily effective against Gram-positive bacteria, including Staphylococcus aureus (particularly methicillin-resistant strains, MRSA). It is used to treat skin and soft tissue infections. Synonyms: ent-(17Z,24EZ)-16α-(Acetyloxy)-3β,11β-dihydroxy-4β,8,14-trimethyl-26-oxo-18-nor-5β,10α-cholesta-17(20),24-dien-21-oic acid; 26-Oxofusidic acid; 27-oxo-Fusidic Acid; (3α,4α,8α,9β,11α,13α,14β,16β,17Z)-16-(Acetyloxy)-3,11-dihydroxy-26-oxo-29-nordammara-17(20),24-dien-21-oic acid; Sodium Fusidate EP Impurity F; Fusidic Acid Impurity F; (2Z)-2-((3R,4S,5S,8S,9S,10S,11R,13R,14S,16S)-16-Acetoxy-3,11-dihydroxy-4,8,10,14-tetramethylhexadecahydro-17H-cyclopenta[a]phenanthren-17-ylidene)-6-methyl-7-oxohept-5-enoic acid. Grade: ≥95%. CAS No. 1415035-94-7. Molecular formula: C31H46O7. Mole weight: 530.70. | |
| Fusidic Acid EP Impurity G | A metabolite of Fusidic acid, which is a steroidal antibiotic belonging to the fusidane class, derived from Fusidium coccineum. Fusidic acid is primarily effective against Gram-positive bacteria, including Staphylococcus aureus (particularly methicillin-resistant strains, MRSA). It is used to treat skin and soft tissue infections. Uses: A metabolite of fusidic acid. Synonyms: (Z)-2-((4S,5S,8S,9S,10S,11R,13R,14S,16S)-16-Acetoxy-11-hydroxy-4,8,10,14-tetramethyl-3-oxohexadecahydro-17H-cyclopenta[a]phenanthren-17-ylidene)-6-methylhept-5-enoic acid; 3-Ketofusidic acid; ent-(17Z)-16α-(Acetyloxy)-11β-hydroxy-4β,8,14-trimethyl-3-oxo-18-nor-5β,10α-cholesta-17(20),24-dien-21-oic acid; 3-Didehydrofusidic acid; (4α,8α,9β,11α,13α,14β,16β,17Z)-16-(Acetyloxy)-11-hydroxy-3-oxo-29-nordammara-17(20),24-dien-21-oic acid; 29-Nor-8α,9β,13α,14β-dammara-17(20),24-dien-21-oic acid, 11α,16β-dihydroxy-3-oxo-, 16-acetate, (Z)-; 3-Oxofusidic acid; 3-Keto Fusidic Acid; Fusidic Acid Impurity G; Sodium Fusidate EP Impurity G. Grade: ≥95%. CAS No. 4680-37-9. Molecular formula: C31H46O6. Mole weight: 514.69. | |
| Fusidic Acid EP Impurity H | A metabolite of Fusidic acid, which is a steroidal antibiotic belonging to the fusidane class, derived from Fusidium coccineum. Fusidic acid is primarily effective against Gram-positive bacteria, including Staphylococcus aureus (particularly methicillin-resistant strains, MRSA). It is used to treat skin and soft tissue infections. Uses: A metabolite of fusidic acid. Synonyms: ent-(17Z)-16α-(Acetyloxy)-3β-hydroxy-4β,8,14-trimethyl-11-oxo-18-nor-5β,10α-cholesta-17(20),24-dien-21-oic acid; 11-Didehydrofusidic acid; 11-Keto fusidic acid; 11-Monoketofusidic acid; (3α,4α,8α,9β,13α,14β,16β,17Z)-16-(Acetyloxy)-3-hydroxy-11-oxo-29-nordammara-17(20),24-dien-21-oic acid; 29-Nor-8α,9β,13α,14β-dammara-17(20),24-dien-21-oic acid, 3α,16β-dihydroxy-11-oxo-, 16-acetate, (Z)-; 11-Ketofusidic acid; 11-Oxofusidic acid; Fusidic Acid Impurity H; (Z)-2-((3R,4S,5S,8S,9S,10S,13R,14S,16S)-16-Acetoxy-3-hydroxy-4,8,10,14-tetramethyl-11-oxohexadecahydro-17H-cyclopenta[a]phenanthren-17-ylidene)-6-methylhept-5-enoic acid; Sodium Fusidate EP Impurity H. Grade: ≥95%. CAS No. 16711-91-4. Molecular formula: C31H46O6. Mole weight: 514.69. | |
| Fusidic Acid EP Impurity I | An impurity of Fusidic acid, which is a steroidal antibiotic belonging to the fusidane class, derived from Fusidium coccineum. Fusidic acid is primarily effective against Gram-positive bacteria, including Staphylococcus aureus (particularly methicillin-resistant strains, MRSA). It is used to treat skin and soft tissue infections. Synonyms: ent-(17Z)-3β,11β,16β-Trihydroxy-4β,8,14-trimethyl-18-nor-5β,10α-cholesta-17(20),24-dien-21-oic acid; 16-epi-Deacetylfusidic acid; (3α,4α,8α,9β,11α,13α,14β,16α,17Z)-3,11,16-Trihydroxy-29-nordammara-17(20),24-dien-21-oic acid; Deacetyl-16-epifusidic acid; 29-Nor-8α,9β,13α,14β-dammara-17(20),24-dien-21-oic acid, 3α,11α,16α-trihydroxy-, (Z)-; 16-Epideacetylfusidic acid; NSC 319631; Fusidic Acid Impurity I; (Z)-6-Methyl-2-((3R,4S,5S,8S,9S,10S,11R,13R,14S,16R)-3,11,16-trihydroxy-4,8,10,14-tetramethylhexadecahydro-17H-cyclopenta[a]phenanthren-17-ylidene)hept-5-enoic acid; Sodium Fusidate EP Impurity I. Grade: ≥95%. CAS No. 5951-83-7. Molecular formula: C29H46O5. Mole weight: 474.68. | |
| Fusidic Acid EP Impurity J | An impurity of Fusidic acid, which is a steroidal antibiotic belonging to the fusidane class, derived from Fusidium coccineum. Fusidic acid is primarily effective against Gram-positive bacteria, including Staphylococcus aureus (particularly methicillin-resistant strains, MRSA). It is used to treat skin and soft tissue infections. Synonyms: ent-(17Z)-3β,11β-Dihydroxy-4β,8,14-trimethyl-18-nor-5β,10α-cholesta-17(20),24-dieno-21(16β)-lactone; 16-epi-Deacetylfusidic acid 21,16-lactone; 29-Nor-8α,9β,13α,14β-dammara-17(20),24-dien-21-oic acid, 3α,11α,16α-trihydroxy-, γ-lactone; Deacetyl-16-epifusidic acid γ-lactone; (3α,4α,8α,9β,11α,13α,14β,16α)-3,11,16-Trihydroxy-29-nordammara-17(20),24-dien-21-oic acid, γ-lactone; Fusidic Acid Impurity J; (2aS,3S,4R,6aS,6bS,7R,8aR,11aR,12aS,12bS)-4,7-Dihydroxy-3,6a,12a,12b-tetramethyl-9-(4-methylpent-3-en-1-yl)-1,2,2a,3,4,5,6,6a,6b,7,8,8a,11a,12,12a,12b-hexadecahydro-10H-naphtho[2',1':4,5]indeno[2,1-b]furan-10-one; Sodium Fusidate EP Impurity J. Grade: ≥95%. CAS No. 13011-12-6. Molecular formula: C29H44O4. Mole weight: 456.66. | |
| Fusidic Acid EP Impurity K | An impurity of Fusidic acid, which is a steroidal antibiotic belonging to the fusidane class, derived from Fusidium coccineum. Fusidic acid is primarily effective against Gram-positive bacteria, including Staphylococcus aureus (particularly methicillin-resistant strains, MRSA). It is used to treat skin and soft tissue infections. Synonyms: 29-Nor-8α,9β,13α,14β-dammara-17(20),24-dien-21-oic acid, 3α,11α,16β-trihydroxy-, γ-lactone; 16-Deacetylfusidic acid γ-lactone; ent-(17Z)-3β,11β-dihydroxy-4β,8,14-trimethyl-18-nor-5β,10α-cholesta-17(20),24-dieno-21(16α)-lactone; Deacetylfusidic acid 21,16-lactone; 16-O-Deacetylfusidic acid lactone; (3α,4α,8α,9β,11α,13α,14β,16β)-3,11,16-Trihydroxy-29-nordammara-17(20),24-dien-21-oic acid, γ-lactone; (2aS,3S,4R,6aS,6bS,7R,8aR,11aS,12aS,12bS)-4,7-Dihydroxy-3,6a,12a,12b-tetramethyl-9-(4-methylpent-3-en-1-yl)-1,2,2a,3,4,5,6,6a,6b,7,8,8a,11a,12,12a,12b-hexadecahydro-10H-naphtho[2',1':4,5]indeno[2,1-b]furan-10-one; Sodium Fusidate EP Impurity K; Fusidic Acid Impurity K. Grade: ≥95%. CAS No. 4701-54-6. Molecular formula: C29H44O4. Mole weight: 456.66. | |
| Fusidic Acid EP Impurity L | An impurity of Fusidic acid, which is a steroidal antibiotic belonging to the fusidane class, derived from Fusidium coccineum. Fusidic acid is primarily effective against Gram-positive bacteria, including Staphylococcus aureus (particularly methicillin-resistant strains, MRSA). It is used to treat skin and soft tissue infections. Synonyms: ent-(17Z)-16α-(Acetyloxy)-3β-hydroxy-4β,8,14-trimethyl-18-nor-5β,10α-cholesta-9(11),17(20),24-trien-21-oic acid; 9,11-Anhydrofusidic acid; (3α,4α,8α,13α,14β,16β,17Z)-16-(Acetyloxy)-3-hydroxy-29-nordammara-9(11),17(20),24-trien-21-oic acid; (Z)-2-((3R,4S,5S,8R,10S,13R,14S,16S)-16-Acetoxy-3-hydroxy-4,8,10,14-tetramethyl-1,2,3,4,5,6,7,8,10,12,13,14,15,16-tetradecahydro-17H-cyclopenta[a]phenanthren-17-ylidene)-6-methylhept-5-enoic acid; 9,11-Anhydro Fusidic Acid; Fusidic Acid Impurity L; Sodium Fusidate EP Impurity L. Grade: ≥95%. CAS No. 74048-41-2. Molecular formula: C31H46O5. Mole weight: 498.70. | |
| Fusidic Acid EP Impurity M | An impurity of Fusidic acid, which is a steroidal antibiotic belonging to the fusidane class, derived from Fusidium coccineum. Fusidic acid is primarily effective against Gram-positive bacteria, including Staphylococcus aureus (particularly methicillin-resistant strains, MRSA). It is used to treat skin and soft tissue infections. Synonyms: ent-(17Z)-16α-(Acetyloxy)-3β-hydroxy-4β,8,14-trimethyl-18-nor-5β,10α-cholesta-17(20),24-dien-21-oic acid; 11-Deoxyfusidic acid; (3α,4α,8α,9β,13α,14β,16β,17Z)-16-(Acetyloxy)-3-hydroxy-29-nordammara-17(20),24-dien-21-oic acid; 11-Deoxy Fusidic Acid; Fusidic Acid Impurity M; (Z)-2-((3R,4S,5S,8S,9S,10S,13R,14S,16S)-16-Acetoxy-3-hydroxy-4,8,10,14-tetramethylhexadecahydro-17H-cyclopenta[a]phenanthren-17-ylidene)-6-methylhept-5-enoic acid; Sodium Fusidate EP Impurity M. Grade: ≥95%. CAS No. 1013937-16-0. Molecular formula: C31H48O5. Mole weight: 500.71. | |
| Fusidic Acid EP Impurity O | An impurity of Fusidic acid, which is a steroidal antibiotic belonging to the fusidane class, derived from Fusidium coccineum. Fusidic acid is primarily effective against Gram-positive bacteria, including Staphylococcus aureus (particularly methicillin-resistant strains, MRSA). It is used to treat skin and soft tissue infections. Synonyms: ent-(17Z)-3β,11β,16α-Trihydroxy-4β,8,14-trimethyl-18-nor-5β,10α-cholesta-17(20),24-dien-21-oic acid; Deacetylfusidic acid; 16-O-Deacetylfusidic acid; Fusidic Acid Impurity O; Sodium Fusidate EP Impurity O; (3α,4α,8α,9β,11α,13α,14β,16β,17Z)-3,11,16-Trihydroxy-29-nordammara-17(20),24-dien-21-oic acid; 29-Nor-8α,9β,13α,14β-dammara-17(20),24-dien-21-oic acid, 3α,11α,16β-trihydroxy-, (Z)-; 16-Desacetylfusidic acid; (Z)-6-Methyl-2-((3R,4S,5S,8S,9S,10S,11R,13R,14S,16S)-3,11,16-trihydroxy-4,8,10,14-tetramethylhexadecahydro-17H-cyclopenta[a]phenanthren-17-ylidene)hept-5-enoic acid. Grade: ≥95%. CAS No. 13090-91-0. Molecular formula: C29H46O5. Mole weight: 474.67. | |
| Fusidic Acid EP Impurity O sodium salt | An impurity of Fusidic acid, which is a steroidal antibiotic belonging to the fusidane class, derived from Fusidium coccineum. Fusidic acid is primarily effective against Gram-positive bacteria, including Staphylococcus aureus (particularly methicillin-resistant strains, MRSA). It is used to treat skin and soft tissue infections. Uses: An impurity of fusidic acid. Synonyms: 29-Nordammara-17(20),24-dien-21-oic acid, 3,11,16-trihydroxy-, monosodium salt, (3α,4α,8α,9β,11α,13α,14β,16β,17Z)-; 16-Deacetyl fusidic acid sodium salt; Sodium Fusidate EP Impurity O; Fusidic Acid EP Impurity O sodium salt; Sodium (Z)-6-methyl-2-((3R,4S,5S,8S,9S,10S,11R,13R,14S,16S)-3,11,16-trihydroxy-4,8,10,14-tetramethylhexadecahydro-17H-cyclopenta[a]phenanthren-17-ylidene)hept-5-enoate; ent-(17Z)-3β,11β,16α-Trihydroxy-4β,8,14-trimethyl-18-nor-5β,10α-cholesta-17(20),24-dien-21-oic acid sodium salt; Deacetylfusidic acid sodium salt; 16-O-Deacetylfusidic acid sodium salt. Grade: ≥95%. CAS No. 55601-53-1. Molecular formula: C29H45NaO5. Mole weight: 496.65. | |
| Futalosine | A new nucleoside analog, was isolated from a fermentation broth of Streptomyces sp. MK359-NF1. An antibiotic cancer inhibitor. Synonyms: 3-[1,5,6-Trideoxy-1-(1,6-dihydro-6-oxo-9H-purin-9-yl)-β-D-ribo-heptofuranuronoyl]benzoic Acid. CAS No. 210644-32-9. Molecular formula: C19H18N4O7. Mole weight: 414.37. | |
| Futibatinib | Futibatinib is an orally bioavailable, selective and irreversible inhibitor of fibroblast growth factor receptors (FGFRs), displaying antineoplastic activity. It inhibits FGFR-mediated signal transduction and tumor cell proliferation. Synonyms: 1-[(3S)-3-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]-1-pyrazolo[3,4-d]pyrimidinyl]-1-pyrrolidinyl]-2-propen-1-one; 1-[(3S)-3-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]pyrazolo[3,4-d]pyrimidin-1-yl]pyrrolidin-1-yl]prop-2-en-1-one. Grade: ≥ 98 %. CAS No. 1448169-71-8. Molecular formula: C22H22N6O3. Mole weight: 418.45. | |
| Futuximab | Futuximab is a chimeric monoclonal antibody directed against EGFR. Futuximab has been used in the research of cancer therapy. Grade: 95%. CAS No. 1310460-85-5. Molecular formula: C6468H10002N1724O2055S46. Mole weight: 146.3 kDa. | |
| Fuzuloparib | Fuzuloparib is a poly (ADP-ribose) polymerase (PARP) inhibitor potentially for the treatment of solid tumours. Synonyms: 4-({4-fluoro-3-[2-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[1,5-a]pyrazine-7(8H)-carbonyl]phenyl}methyl)phthalazin-1(2H)-one; 1(2H)-Phthalazinone, 4-[[3-[[5,6-dihydro-2-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrazin-7(8H)-yl]carbonyl]-4-fluorophenyl]methyl]-; Fuzuopali; SHR-3162; Fuzuloparibum. Grade: ≥98%. CAS No. 1358715-18-0. Molecular formula: C22H16F4N6O2. Mole weight: 472.40. | |
| FW1256 | Exogenous H2S, as we know, has anti-inflammatory effects both in macrophages and in animal models. FW1256 is a slow release H2S dononr and it is much more potent in cells. FW1256 may be useful for studies of H2S in biology and could also have future therapeutic value in inflammatory conditions. Uses: Anti-inflammation. Synonyms: FW1256; FW-1256; FW 1256. 2-phenyl-3H-benzo[d][1,3,2]oxazaphosphole 2-sulfide. Grade: 98%. CAS No. 117089-08-4. Molecular formula: C12H10NOPS. Mole weight: 247.25. | |
| FX1 | FX1 is a selective inhibitor of B cell lymphoma 6 (BCL6) (IC50 = 35 μM in reporter assays), which can disrupt formation of the BCL6 repression complex, reactivate BCL6 target genes and mimick the phenotype of mice engineered to express BCL6 with corepressor binding site mutations. FX1 also inhibits ABC-DLBCL cells. Synonyms: FX1; FX-1; FX 1. SCHEMBL16323186; CHEBI:133537; AKOS015865677; CS-7688; HY-102027; 3-[(5Z)-5-(5-chloro-2-oxo-1H-indol-3-ylidene)-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]propanoic acid. Grade: 99.75 %. CAS No. 1426138-42-2. Molecular formula: C14H9ClN2O4S2. Mole weight: 368.82. | |
| FXR/TGR5 agonist 1 | FXR/TGR5 agonist 1, a dual agonist of FXR and TGR5, can be used to treat fatty liver disease. Synonyms: N-(3-chloro-5-methoxyphenyl)-N-((4-(3-cyano-4-methoxyphenyl)bicyclo[2.2.2]octan-1-yl)methyl)-3-methylisonicotinamide. CAS No. 2677689-72-2. Molecular formula: C31H32ClN3O3. Mole weight: 530.06. | |
| FY26 (complex) | This active moleculr is a Os(II) anticancer drug candidate. It can generate reactive oxygen species and disrupt the redox balance in cancer cells. Using FY26 and nontoxic doses of L-BSO together allows the potentiation of its anticancer activity and inpartantly, it improves the selectivity for cancer cells versus normal fibroblasts. FY26 can shut down a cancer cell by exploiting weaknesses inherent in their energy generation. Uses: Anti-cancer. Synonyms: FY26; FY-26; FY 26. Osmium(1+)?, [N,?N-dimethyl-4-[2-(2-pyridinyl-κN)?diazenyl-κN1]?benzenamine]?iodo[(1,?2,?3,?4,?5,?6-η)?-1-methyl-4-(1-methylethyl)?benzene]?-, hexafluorophosphate(?1-) (1:1). Grade: 98%. CAS No. 1255143-82-8. Molecular formula: C23H28F6IN4OsP. Mole weight: 822.60. | |
| G007-LK | G007-LK is a potent, "rule of 5" compliant and a metabolically stable TNKS1/2 inhibitor. G007-LK displayed high selectivity toward tankyrases 1 and 2 with biochemical IC50 values of 46 nM and 25 nM, respectively, and a cellular IC50 value of 50 nM combined with an excellent pharmacokinetic profile in mice. G007-LK was first discovered by Dr. Stefan Krauss's team. Synonyms: G007LK; G007LK; G007 LK. Grade: >98%. CAS No. 1380672-07-0. Molecular formula: C25H16ClN7O3S. Mole weight: 529.96. | |
| G0507 | G0507 is an inhibitor of Escherichia coli growth and induces the extracytoplasmic E stress response. G0507 acts as a chemical probe to dissect lipoprotein trafficking in Gram-negative bacteria. Synonyms: G 0507. Grade: 98%. CAS No. 1223998-29-5. Molecular formula: C18H15N3O3S. Mole weight: 353.39. | |
| G-1 | G-1 is a nonsteroidal, high-affinity, selective agonist of GPR30 and a potent and selective GPER agonist. It displays no activity at ERα and ERβ at concentrations up to 10 μM. It increases cytosolic Ca2+ and inhibits migration of SKBr3 cells and MCF-7 cel. Synonyms: (±)-1-[(3aR*,4S*,9bS*)-4-(6-Bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-8-yl]-ethanone; rel-1-[4-(6-bromo-1,3-benzodioxol-5-yl)-3aR,4S,5,9bS-tetrahydro-3H-cyclopenta[c]quinolin-8-yl]-ethanone. Grade: > 95%. CAS No. 881639-98-1. Molecular formula: C21H18BrNO3. Mole weight: 412.29. | |
| G140 | G140 is a potent and selective cyclic GMP-AMP synthase (cGAS) inhibitor, with IC50s of 14.0?nM and 442?nM for h-cGAS and m-cGAS, respectively. It has anti-inflammatory activity. Synonyms: 1-(6,7-Dichloro-9-(1-methyl-1H-pyrazol-3-yl)-3,4-dihydro-1H-pyrido[4,3-b]indol-2(5H)-yl)-2-hydroxyethanone; Ethanone, 1-[6,7-dichloro-1,3,4,5-tetrahydro-9-(1-methyl-1H-pyrazol-3-yl)-2H-pyrido[4,3-b]indol-2-yl]-2-hydroxy-; 1-[6,7-Dichloro-9-(1-methyl-1H-pyrazol-3-yl)-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl]-2-hydroxyethanone. Grade: ≥98%. CAS No. 2369751-07-3. Molecular formula: C17H16Cl2N4O2. Mole weight: 379.24. | |
| G150 | G150 is a potent and selective inhibitor of human cyclic GMP-AMP synthase (cGAS) with IC50 of 10.2 nM. CAS No. 2369751-30-2. Molecular formula: C18H16Cl2N4O2. Mole weight: 391.25. | |
| G1F Glycan, 2-AA labelled | G1F Glycan, 2-AA labelled, a noteworthy carbohydrate molecule, serves as a potent tool for glycomic analysis. Through its ability to detect glycan biomarkers, it has implicated itself as crucial in analyzing aberrant glycosylation patterns in diseases including cancer. This molecular fingerprint finds broad application in mass spectrometry-based glycomic profiling. By furnishing invaluable insights into the progressive role of glycosylation in disease, researchers can harness the potential of this versatile labelled glycan to enhance diagnostic approaches. | |
| G1F Glycan, 2-AB labelled | G1F Glycan, 2-AB labelled. | |
| G244-LM | G244-LM is a potent and specific small-molecule tankyrase inhibitors, which reduces Wnt/β-catenin signaling by preventing poly(ADP-ribosyl)ation-dependent AXIN degradation, thereby promoting β-catenin destabilization. Synonyms: 3,5,7,8-tetrahydro-2-[4-[2-(methylsulfonyl)phenyl]-1-piperazinyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one. CAS No. 1563007-08-8. Molecular formula: C18H22N4O3S2. Mole weight: 406.5. | |
| G 28UCM | G 28UCM is a fatty acid synthase inhibitor that potently inhibits the proliferation of breast cancer cell. G 28UCM blocks HER2 signaling, induces apoptosis, and suppresses growth of breast cancer xenografts in mice without causing anorexia. Synonyms: 3-(3,4,5-Trihydroxybenzoyloxy)naphthalen-1-yl 3,4,5-trihydroxybenzoate; 1,3-Bis[(3,4,5-Trihydroxybenzoyl)Oxy]Naphthalene. Grade: ≥98% by HPLC. CAS No. 1094451-90-7. Molecular formula: C24H16O10. Mole weight: 464.38. | |
| G3130 | G3130 is a reversible Hsp90 inhibitor with potential anticancer activity. G3130 demonstrated cellular activities (in Her-2 degradation and activation of Hsp70 promoter) consistent with the inhibition of cellular Hsp90 functions. Synonyms: G-3130; G 3130; 4-(4-(1H-imidazol-4-yl)-1H-pyrazol-3-yl)-6-ethylbenzene-1,3-diol. Grade: 98%. CAS No. 848952-37-4. Molecular formula: C14H14N4O2. Mole weight: 270.29. | |
| G-36 | G-36 is an antagonist of G protein-coupled estrogen receptor (GPER). It selectively inhibits estrogen-mediated activation of PI3-K by GPER and estrogen-mediated calcium mobilization (IC50 = 112 nM). Synonyms: GRB-G36; G-36; G36; G 36. (±)-(3aR,4S,9bS)-4-(6-Bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydro-8-(1-methylethyl)-3H-cyclopenta[c]quinoline. Grade: ≥99% by HPLC. CAS No. 1392487-51-2. Molecular formula: C22H22BrNO2. Mole weight: 412.33. | |
| G3-C12 acetate | G3-C12 acetate, a galectin-3 binding peptide with Kd of 88 nM, shows anticancer activity. Molecular formula: C76H119N23O25S2. Mole weight: 1819.03. | |
| G-5555 | G-5555 is a selective PAK1 Inhibitor (Ki=3.7 nM) with low clearance (CLp = 3.4 mL/min/kg) and high oral bioavailability (F = 72%). IC50: PAK2= 11 nM, SIK2= 9 mM, KHS1= 10 mM. Synonyms: G - 5555; G 5555; G5555; 8-[(5-amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one59T8-(((2r,5r)-5-amino-1,3-dioxan-2-yl)methyl)-6-(2-chloro-4-(6-methylpyridin-2-yl)phenyl)-2-(methylamino)pyrido[2,3-d]pyrimidin-7. CAS No. 1648863-90-4. Molecular formula: C25H25ClN6O3. Mole weight: 492.96. | |
| G-5555 hydrochloride | G-5555 hydrochloride is the hydrochloride salt of G-5555 which is a potent and selective p21-activated kinase 1 (PAK1) inhibitor (Ki = 3.7 nM). G-5555 was potent, showing good activity in the pMEK cellular assay, had improved permeability, and importantly, displayed low hERG channel activity (<50% inhibition at 10 μM). Synonyms: 8-[(5-amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one; hydrochloride; G-5555 (hydrochloride); G 5555 (hydrochloride); G5555 (hydrochloride). Molecular formula: C25H26Cl2N6O3. Mole weight: 529.42. | |
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