BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Epacadostat | Epacadostat, also known as INCB024360 or INCB24360, is a potent and selective IDO1 inhibitor with IC50 of 71.8 nM±17.5 nM, with potential immunomodulating and antineoplastic activities. It has been shown to promote T and natural killer-cell growth, to increase IFN-γ production, and to reduce conversion to regulatory T (Treg)-like cells in a coculture system of human allogeneic lymphocytes with either dendritic cells or tumor cells. Synonyms: IDO inhibitor 1; 1,2,5-Oxadiazole-3-carboximidamide, 4-[[2-[(aminosulfonyl)amino]ethyl]amino]-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-, [C(Z)]-; [C(Z)]-4-[[2-[(Aminosulfonyl)amino]ethyl]amino]-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide; ICBN 24360; ICBN-24360; ICBN24360; INCB 024360; INCB024360; INCB-024360. Grades: ≥95%. CAS No. 1204669-58-8. Molecular formula: C11H13BrFN7O4S. Mole weight: 438.23. |  |
| Epalrestat | Epalrestat is an aldose reductase inhibitor with IC50 of 72 nM. Uses: Enzyme inhibitors. Synonyms: Epalrestat; Kinedak; ONO-2235; ONO 2235; ONO2235; Sorbistat. Grades: >98%. CAS No. 82159-09-9. Molecular formula: C15H13NO3S2. Mole weight: 319.4. | |
| Epalrestat Dimer | Dimer impurity of Epalrestat. Epalrestat is a carboxylic acid-based inhibitor of aldose reductase. Synonyms: Dimer of 5Z-[(2E)-2-methyl-3-phenyl-2-propen-1-ylidene]-4-oxo-2-thioxo-3-thiazolidineacetic acid. Grades: > 95%. Molecular formula: C30H26N2O6S4. Mole weight: 638.81. | |
| Epalrestat (E, E)-Isomer | A stereoisomer of Epalrestat. Epalrestat is a carboxylic acid-based inhibitor of aldose reductase. Synonyms: 2-((Z)-5-((Z)-2-Methyl-3-phenylallylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid. Grades: > 95%. Molecular formula: C15H13NO3S2. Mole weight: 319.40. | |
| Epalrestat (E, Z)-Isomer | A stereoisomer of Epalrestat. Epalrestat is a carboxylic acid-based inhibitor of aldose reductase. Synonyms: (E,Z)-5-(2-Methyl-3-phenyl-2-propen-1-ylidene)-4-oxo-2-thioxo-3-thiazolidineacetic Acid. Grades: > 95%. Molecular formula: C15H13NO3S2. Mole weight: 319.40. | |
| Epalrestat (Z, Z)-Isomer | A stereoisomer of Epalrestat. Epalrestat is a carboxylic acid-based inhibitor of aldose reductase. Synonyms: 2-((Z)-5-((Z)-2-Methyl-3-phenylallylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid. Grades: > 95%. Molecular formula: C15H13NO3S2. Mole weight: 319.40. | |
| Eperisone HCl | Eperisone relaxes both skeletal muscles and vascular smooth muscles. Uses: Anticonvulsants. Synonyms: 1-(4-Ethylphenyl)-2-methyl-3-(1-piperidinyl)-1-propanone Hydrochloride. Grades: > 95%. CAS No. 56839-43-1. Molecular formula: C17H25NO. HCl. Mole weight: 259.39 36.46. | |
| (-)-Epiafzelechin 7-O-Glucopyranoside | A a derivative of (-)-Epiafzelechin. (-)-Epiafzelechin exhibits various modes of action in suppressing HSV-2 multiplication. Synonyms: Symposide; Beta-D-Glucopyranoside,(2R,3R)-3,4-dihydro-3,5-dihydroxy-2-(4-hydroxyphenyl)-2H-1-benzopyran-7-yl. Grades: > 95%. CAS No. 126595-96-8. Molecular formula: C21H24O10. Mole weight: 436.42. | |
| Epi-Galantamine | Epi-Galantamine is a selective acetylcholinesterase inhibitor. Synonyms: (4aS,6S,8aS)-4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol; 2-Epigalanthamine; (-)-Epigalanthamine; SPH 1068; 3-Epigalanthamine; Galantamine Impurity B. Grades: > 95%. CAS No. 1668-85-5. Molecular formula: C17H21NO3. Mole weight: 287.36. | |
| Epi-Galantamine N-Oxide | Synonyms: (4aS,6S,8aS)-4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol 11-Oxide. Grades: > 95%. CAS No. 366485-18-9. Molecular formula: C17H21NO4. Mole weight: 303.36. | |
| Epinastine HCl | Cas No. 108929-04-0. | |
| Epinastine hydrobromide | Epinastine is an antihistamine and mast cell stabilizer that is used in eye drops to treat allergic conjunctivitis. Synonyms: (+/-)-3-amino-9,13b-dihydro-1h-dibenz[c,f]imidazo[1,5-a]azepine hydrobromide; Epinastine HBr. CAS No. 127786-29-2. Molecular formula: C16H15N3.HBr. Mole weight: 330.23. | |
| Epinastine Related Compound A | An impurity of Epinastine. Epinastine is a non-sedating ophthalmic antihistamine that antagonizes histamine H5 receptors and prevents the release of pro-inflammatory mediators from mast cells and eosinophils. Synonyms: 6-Aminomethyl-5,6-dihydromorphanthridine. Grades: > 95%. CAS No. 41218-84-2. Molecular formula: C15H16N2. Mole weight: 224.31. | |
| (+)-Epinephrine (-)-Bitartrate | (+)-Epinephrine (-)-Bitartrate is an enantiomer of Epinephrine. Epinephrine is an endogenous catcholamine with combined α-and β-agonist activity and its principal sympathomimetic hormone is produced by the adrenal medulla. Synonyms: (+)-3,4-Dihydroxy-α-[(methylamino)methyl] Benzyl Alcohol (-)-Tartrate; (S)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol (R*,R*)]-2,3-Dihydroxybutanedioate. Grades: ≥95%. CAS No. 21282-30-4. Molecular formula: C13H19NO9. Mole weight: 333.29. | |
| Epinephrine Glucuronide | A metabolite of Epinephrine. Epinephrine is an endogenous catcholamine with combined α-and β-agonist activity and its principal sympathomimetic hormone is produced by the adrenal medulla. Synonyms: β-D-Glucopyranosiduronic acid, 2-hydroxy-4-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenyl; 2-Hydroxy-4-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenyl β-D-glucopyranosiduronic acid; β-D-Glucopyranosiduronic acid, 2-hydroxy-4-[1-hydroxy-2-(methylamino)ethyl]phenyl, (R)-; L-Epinephrine β-D-Glucuronide. Grades: ≥95%. CAS No. 54964-61-3. Molecular formula: C15H21NO9. Mole weight: 359.33. | |
| (+/-)-Epinephrine Hydrochloride | (±)-Epinephrine is a natural neurotransmitter that is released from the adrenal medulla and activates adrenoceptors (Kis = 15, 735, and 3,970 nM for α1A-, β2-, and β1-adrenergic receptors, respectively). (±)-Epinephrine hydrochloride is an adrenergic receptor agonist. Uses: Adrenergic beta-agonists. Synonyms: 4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol Hydrochloride; (±)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol Hydrochloride; 3,4-Dihydroxy-α-[(methylamino)methyl]-benzyl Alcohol Hydrochloride; (±)-Adrenaline Hydrochloride; Asthmanefrin; Racepinephrine Hydrochloride; Vaponefrin; dl-Adrenaline Hydrochloride; dl-Epinephrine Hydrochloride. Grades: ≥95%. CAS No. 329-63-5. Molecular formula: C9H14ClNO3. Mole weight: 219.66. | |
| Epinephrine Impurity 10 | An impurity of Epinephrine. Epinephrine is an endogenous catcholamine with combined α-and β-agonist activity and its principal sympathomimetic hormone is produced by the adrenal medulla. Molecular formula: C8H9NO4S. Mole weight: 215.23. | |
| Epinephrine Impurity 11 | An impurity of Epinephrine. Epinephrine is an endogenous catcholamine with combined α-and β-agonist activity and its principal sympathomimetic hormone is produced by the adrenal medulla. Molecular formula: C8H9NO4S. Mole weight: 215.23. | |
| Epinephrine Impurity 1 Sodium Salt | An impurity of Epinephrine. Epinephrine is an endogenous catcholamine with combined α-and β-agonist activity and its principal sympathomimetic hormone is produced by the adrenal medulla. CAS No. 21093-14-1. Molecular formula: C9H12NO6SNa. Mole weight: 285.25. | |
| Epinephrine Impurity 2 DiHCl | An impurity of Epinephrine. Epinephrine is an endogenous catcholamine with combined α-and β-agonist activity and its principal sympathomimetic hormone is produced by the adrenal medulla. Molecular formula: C16H20Cl2N2O4. Mole weight: 375.25. | |
| Epinephrine Impurity 4 | An impurity of Epinephrine. Epinephrine is an endogenous catcholamine with combined α-and β-agonist activity and its principal sympathomimetic hormone is produced by the adrenal medulla. Synonyms: 1H-Indole-3-sulfonic acid, 2,3,5,6-tetrahydro-1-methyl-5,6-dioxo-; 2,3,5,6-Tetrahydro-1-methyl-5,6-dioxo-1H-indole-3-sulfonic acid; 3-Indolinesulfonic acid, 5,6-dihydro-1-methyl-5,6-dioxo-. CAS No. 94217-53-5. Molecular formula: C9H9NO5S. Mole weight: 243.24. | |
| Epinephrine Impurity 5 | An impurity of Epinephrine. Epinephrine is an endogenous catcholamine with combined α-and β-agonist activity and its principal sympathomimetic hormone is produced by the adrenal medulla. Molecular formula: C9H11NO5S. Mole weight: 245.25. | |
| Epinephrine Impurity 6 | An impurity of Epinephrine. Epinephrine is an endogenous catcholamine with combined α-and β-agonist activity and its principal sympathomimetic hormone is produced by the adrenal medulla. Molecular formula: C18H24N2O7S. Mole weight: 412.46. | |
| Epinephrine Impurity 7 | An impurity of Epinephrine. Epinephrine is an endogenous catcholamine with combined α-and β-agonist activity and its principal sympathomimetic hormone is produced by the adrenal medulla. Synonyms: 1H-Indole-3,5,6-triol, 2,3-dihydro-1-methyl-, (R)-. CAS No. 62322-82-1. Molecular formula: C9H11NO3. Mole weight: 181.19. | |
| Epinephrine Impurity 9 | An impurity of Epinephrine. Epinephrine is an endogenous catcholamine with combined α-and β-agonist activity and its principal sympathomimetic hormone is produced by the adrenal medulla. Molecular formula: C9H7NO2. Mole weight: 161.16. | |
| Epinephrine o-Quinone | An impurity of Epinephrine. Epinephrine is an endogenous catcholamine with combined α-and β-agonist activity and its principal sympathomimetic hormone is produced by the adrenal medulla. Synonyms: Dehydroadrenaline; 4-[1-hydroxy-2-(methylamino)ethyl]-o-Benzoquinone; Adrenalinequinone. CAS No. 672-73-1. Molecular formula: C9H11NO3. Mole weight: 181.19. | |
| Epinephrine Sulfate | A derivative of Epinephrine. Epinephrine is a natural neurotransmitter that is released from the adrenal medulla and activates adrenoceptors. Synonyms: 1,2-Benzenediol, 4-[(1R)-1-hydroxy-2-(methylamino)ethyl]-, mono(hydrogen sulfate) (ester); 1,2-Benzenediol, 4-[1-hydroxy-2-(methylamino)ethyl]-, mono(hydrogen sulfate) (ester), (R)-; Adrenaline sulfate. Grades: ≥95%. CAS No. 77469-50-2. Molecular formula: C9H13NO6S. Mole weight: 263.27. | |
| Epiprednisolone 21-Acetate | 11-epi-Prednisolone 21-Acetate is an impurity of Prednisolone, which is a glucocorticoid and an anti-inflammatory drug used to treat central nervous system disorders. Synonyms: (11α)-11,17-Dihydroxy-3,20-dioxopregna-1,4-dien-21-yl acetate; Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-11,17-dihydroxy-, (11α)-; 2-((8S,9S,10R,11R,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate; 11-epi-Prednisolone 21-Acetate; (11α)-21-(Acetyloxy)-11,17-dihydroxypregna-1,4-diene-3,20-dione; 21-Acetoxy-11α,17-dihydroxypregna-1,4-diene-3,20-dione. Grades: >95%. CAS No. 3597-59-9. Molecular formula: C23H30O6. Mole weight: 402.48. | |
| Epirubicin Impurity G | Cas No. 1046827-43-3. | |
| Epithalone | Epithalon is a synthetic tetra-peptide used to regulate the cell cycle through up-regulation of telomerase activity showing anticancer and anti-tumor metastatic effect. Uses: Regulate the cell cycle through up-regulation of telomerase activity. Synonyms: H-Ala-Glu-Asp-Gly-OH; (S)-4-((S)-2-aminopropanamido)-5-(((S)-3-carboxy-1-((carboxymethyl)amino)-1-oxopropan-2-yl)amino)-5-oxopentanoic acid. Grades: ≥98%. CAS No. 307297-39-8. Molecular formula: C14H22N4O9. Mole weight: 390.35. | |
| Eplerenone EP Impurity A | An impurity of Eplerenone. Eplerenone is a potassium-sparing diuretic that selectively blocks aldosterone activation of the mineralcorticoid receptor, demonstrating little activity towards other steroid receptors. Synonyms: (7α,17α)- 9,17-Dihydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid Di-γ-lactone. Grades: > 95%. CAS No. 209253-67-8. Molecular formula: C23H28O5. Mole weight: 384.48. | |
| Eplerenone EP Impurity B | An impurity of Eplerenone. Eplerenone is a potassium-sparing diuretic that selectively blocks aldosterone activation of the mineralcorticoid receptor, demonstrating little activity towards other steroid receptors. Synonyms: (7α, 11α, 12α, 17α)-11, 12-Epoxy-17-hydroxy-3-oxo-pregn-4-ene-7, 21-dicarboxylic Acid Lactone, Methyl Ester. Grades: > 95%. CAS No. 192704-82-8. Molecular formula: C24H30O6. Mole weight: 414.50. | |
| Eplerenone EP Impurity D | An impurity of Eplerenone. Eplerenone is a potassium-sparing diuretic that selectively blocks aldosterone activation of the mineralcorticoid receptor, demonstrating little activity towards other steroid receptors. Synonyms: Eplerenone 7-Carboxylic Acid; 9,11-Epoxy-17-hydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid γ-Lactone. Grades: > 95%. CAS No. 209253-82-7. Molecular formula: C23H28O6. Mole weight: 400.48. | |
| Eplerenone EP Impurity E | An impurity of Eplerenone. Eplerenone is a potassium-sparing diuretic that selectively blocks aldosterone activation of the mineralcorticoid receptor, demonstrating little activity towards other steroid receptors. Synonyms: 7β-Eplerenone; (7β,11α,17α)-9,11-Epoxy-17-hydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid γ-Lactone Methyl Ester. Grades: > 95%. CAS No. 209253-81-6. Molecular formula: C24H30O6. Mole weight: 414.50. | |
| Eplerenone EP Impurity F Potassium Salt | An impurity of Eplerenone. Eplerenone is a potassium-sparing diuretic that selectively blocks aldosterone activation of the mineralcorticoid receptor, demonstrating little activity towards other steroid receptors. Synonyms: (7α,11α,17α)-9,11-Epoxy-17-hydroxy-3-oxopregn-4-ene-7,21-dicarboxylic Acid; 7-Methyl Ester Monopotassium Salt; SC 70303; Eplerenone EP Impurity F Potassium Salt. Grades: > 95%. CAS No. 95716-98-6. Molecular formula: C24H31O7K. Mole weight: 470.6. | |
| Eplerenone EP Impurity G | An impurity of Eplerenone. Eplerenone is a potassium-sparing diuretic that selectively blocks aldosterone activation of the mineralcorticoid receptor, demonstrating little activity towards other steroid receptors. Synonyms: Mexrenone; Spiro[17H-cyclopenta[a]phenanthrene-17,2'(5'H)-furan], pregn-4-ene-7,21-dicarboxylic acid deriv.; 17-Hydroxy-3-oxo-17α-pregn-4-ene-7α,21-dicarboxylic acid methyl ester γ-lactone. Grades: > 95%. CAS No. 41020-65-9. Molecular formula: C24H32O5. Mole weight: 400.52. | |
| Eplerenone Impurity 1 | An impurity of Eplerenone. Eplerenone is a potassium-sparing diuretic that selectively blocks aldosterone activation of the mineralcorticoid receptor, demonstrating little activity towards other steroid receptors. Synonyms: (2'R,7S,10R,11R,13S,14S)-methyl 11-hydroxy-10, 13-dimethyl-3, 5'-dioxo-1, 2, 3, 4', 5', 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16-hexadecahydro-3'H-spiro[cyclopenta[a]phenanthrene-17, 2'-furan]-7-carboxylate. Grades: > 95%. Molecular formula: C24H32O6. Mole weight: 416.52. | |
| Epoxiconazole | Epoxiconazole is a fungicide used to control a wide range of fungal diseases. Synonyms: 1H-1,2,4-Triazole, 1-[[(2R,3S)-3-(2-chlorophenyl)-2-(4-fluorophenyl)-2-oxiranyl]methyl]-, rel-; 1H-1,2,4-Triazole, 1-[[(2R,3S)-3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiranyl]methyl]-, rel-; 1H-1,2,4-Triazole, 1-[[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiranyl]methyl]-, cis-(±)-; rel-1-[[(2R,3S)-3-(2-Chlorophenyl)-2-(4-fluorophenyl)-2-oxiranyl]methyl]-1H-1,2,4-triazole; BAS 480F; Fuhuanzuo; Opal; Opal (fungicide); Opus; Rubric. Grades: ≥95%. CAS No. 133855-98-8. Molecular formula: C17H13ClFN3O. Mole weight: 329.76. | |
| Epoxy Exemestane (6-Alfa Isomer) | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6α-Spiro[androsta-1,4-diene-6,2'-oxiran]-3,17-dione. Grades: > 95%. CAS No. 152764-24-4. Molecular formula: C20H24O3. Mole weight: 312.41. | |
| Epoxy Exemestane (6-Beta Isomer) | A derivative of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6β-Spiro[androsta-1,4-diene-6,2'-oxiran]-3,17-dione. Grades: > 95%. CAS No. 152764-31-3. Molecular formula: C20H24O3. Mole weight: 312.41. | |
| Eprosartan acyl glucuronide | A derivative of Eprosartan. Eprosartan is an angiotensin II receptor antagonist used for the treatment of high blood pressure. Synonyms: (E)-3-[2-Butyl-1-[(4-carboxyphenyl)methyl]imidazol-5-yl]-2-(2-thienylmethyl)-2-propenoic Acid β-D-Glucuronide. Grades: > 95%. Molecular formula: C29H32N2O10S. Mole weight: 600.65. | |
| Eprosartan Impurity 1 | An impurity of Eprosartan. Eprosartan is an angiotensin II receptor antagonist used for the treatment of high blood pressure. Synonyms: (E)-methyl 4-((2-butyl-5-(3-ethoxy-3-oxo-2-(thiophen-2-ylmethyl)prop-1-en-1-yl)-1H-imidazol-1-yl)methyl)benzoate. Grades: > 95%. Molecular formula: C26H30N2O4S. Mole weight: 466.60. | |
| Eprosartan Impurity 2 | An impurity of Eprosartan. Eprosartan is an angiotensin II receptor antagonist used for the treatment of high blood pressure. Synonyms: 2-((2-butyl-1-(4-carboxybenzyl)-1H-imidazol-5-yl)methylene)malonic acid. Grades: > 95%. Molecular formula: C19H20N2O6. Mole weight: 372.38. | |
| Eprosartan Impurity 3 | An impurity of Eprosartan. Eprosartan is an angiotensin II receptor antagonist used for the treatment of high blood pressure. Synonyms: (E)-4-((2-butyl-5-(2-carboxyvinyl)-1H-imidazol-1-yl)methyl)benzoic acid. Grades: > 95%. Molecular formula: C18H20N2O4. CH4O3S. Mole weight: 328.37 96.11. | |
| Eprosartan Impurity 4 | An impurity of Eprosartan. Eprosartan is an angiotensin II receptor antagonist used for the treatment of high blood pressure. Synonyms: 4-((2-butyl-5-formyl-1H-imidazol-1-yl)methyl)benzoic acid. Grades: > 95%. CAS No. 152146-59-3. Molecular formula: C16H18N2O3. Mole weight: 286.33. | |
| Eprosartan Impurity 5 | An impurity of Eprosartan. Eprosartan is an angiotensin II receptor antagonist used for the treatment of high blood pressure. Synonyms: (E)-4-((2-butyl-5-(3-carboxy-1,4-di(thiophen-2-yl)but-2-en-2-yl)-1H-imidazol-1-yl)methyl)benzoic acid. Grades: > 95%. Molecular formula: C28H28N2O4S2. Mole weight: 520.69. | |
| Eprosartan Mesylate | Eprosartan is a nonpeptide angiotensin II receptor antagonist, [3H]-eprosartan binds to the AT1 receptor with KD of 0.83 nM in rat vascular smooth muscle cells. Synonyms: Eprosartan Mesylate; Teveten; Futuran; Navixen; Regulaten; SK and F 108566; SKF-108566. Grades: >98%. CAS No. 144143-96-4. Molecular formula: C23H24N2O4S.CH4O3S. Mole weight: 520.62. | |
| Eprosartan related compound A | An impurity of Eprosartan. Eprosartan is an angiotensin II receptor antagonist used for the treatment of high blood pressure. Synonyms: N-Descarboxyphenyl eprospartan; ((E)-3-(2-Butyl-1H-imidazol-5-yl)-2-(thiophen-2-ylmethyl)Acrylic Acid. Grades: > 95%. CAS No. 1169702-90-2. Molecular formula: C15H18N2O2S. Mole weight: 290.39. | |
| Eprosartan related compound C | An impurity of Eprosartan. Eprosartan is an angiotensin II receptor antagonist used for the treatment of high blood pressure. Synonyms: (2-Thenyl)malonic acid, 2-(2-Thienylmethyl)propanedioic acid, 2-(Thiophen-2-ylmethyl)malonic acid. Grades: > 95%. CAS No. 4475-24-5. Molecular formula: C8H8O4S. Mole weight: 200.21. | |
| Eprosartan related compound F | An impurity of Eprosartan. Eprosartan is an angiotensin II receptor antagonist used for the treatment of high blood pressure. Synonyms: (Z)-Eprosartan; (αZ)-α-[[2-Butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazol-5-yl]methylene]-2-thiophenepropanoic Acid. Grades: > 95%. CAS No. 148674-39-9. Molecular formula: C23H24N2O4S. Mole weight: 424.52. | |
| Eptifibatide | An arginin-glycin-aspartat-mimetic, reversibly binds to platelets to reduce the risk of cardiac ischemic events. Uses: Platelet aggregation inhibitors. Synonyms: L-Cysteinamide, N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-α-aspartyl-L-tryptophyl-L-prolyl-, cyclic (1?6)-disulfide; Eftifibatide; Integrelin; Integrilin; Intrifiban; Mpr-Har-Gly-Asp-Trp-Pro-Cys-NH2; deamino-cysteinyl-L-homoarginyl-glycyl-L-alpha-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide (1->7)-disulfide. Grades: 98%. CAS No. 188627-80-7. Molecular formula: C35H49N11O9S2. Mole weight: 831.97. | |
| EPZ011989 | EPZ011989 is a potent, orally-available EZH2 inhibitor with robust in vivo activity. EPZ011989 demonstrates significant tumor growth inhibition in a mouse xenograft model of human B cell lymphoma. Synonyms: EPZ011989; EPZ-011989; EPZ 011989. Grades: 98%. CAS No. 1598383-40-4. Molecular formula: C35H51N5O4. Mole weight: 605.82. | |
| EPZ015666 | EPZ015666 shows potent cellular activity that blocks symmetric dimethylation of SmD3 and inhibit proliferation of MCL cell lines (Z-138, Granta-519, Maver-1, Mino, and Jeko-1) with IC50 of 96-904 nM. Synonyms: EPZ015666; EPZ-015666; EPZ 015666; GSK3235025; GSK-3235025; GSK 3235025. Grades: >98%. CAS No. 1616391-65-1. Molecular formula: C20H25N5O3. Mole weight: 383.44. | |
| EPZ015866 | EPZ015866,also called as GSK591, is a chemical probe for PRMT5 which has a role in diverse cellular processes including tumorigenesis. It exhibits excellent selectivity against a panel of methyltransferases. Inhibits the PRMT5/MEP50 complex from methylati. Synonyms: GSK591; GSK-591; GSK 591; EPZ015866; EPZ-015866; EPZ 015866; GSK 3203591; GSK-3203591; GSK3203591; 2- (cyclobutyl amino) -N- [ (2S) -3- (3, 4-di hydro-1H-isoquinolin-2-yl ) -2- hydroxypropyl ] pyridine-4-carboxamide EPZ015866GSK591GTPL8954S CHEMBL16220740GSK32035912- (cyclobutyl amino) -N- [ (2S) -2- hydroxy-3- (1, 2, 3, 4-tetra hydroisoquinolin-2-yl ) propyl ] pyridine-4-carbo. CAS No. 1616391-87-7. Molecular formula: C22H28N4O2. Mole weight: 380.48. | |
| EPZ-6438 | EPZ-6438 is a potent, selective, and orally bioavailable small-molecule inhibitor of EZH2 enzymatic activity. EPZ-6438 induces apoptosis and differentiation specifically in SMARCB1-deleted MRT cells. Treatment of xenograft-bearing mice with EPZ-6438 leads to dose-dependent regression of MRTs with correlative diminution of intratumoral trimethylation levels of lysine 27 on histone H3, and prevention of tumor regrowth after dosing cessation. These data demonstrate the dependency of SMARCB1 mutant MRTs on EZH2 enzymatic activity and portend the utility of EZH2-targeted drugs for the treatment of these genetically defined cancers. EPZ-6438 is currently in clinical trials. Synonyms: EPZ-6438; EPZ 6438; EPZ6438; E7438; E-7438; E 7438; Tazemetostat. Grades: 98%. CAS No. 1403254-99-8. Molecular formula: C34H44N4O4. Mole weight: 572.75. | |
| Equilenin | Equilenin is an estrogenic steroid hormone obtained from the urine of pregnant mares. Synonyms: 3-Hydroxyestra-1,3,5,7,9-pentaen-17-one; (+)-Equilenin; 3-Hydroxyestra-1,3,5(10),6,8-pentaen-17-one. Grades: > 95%. CAS No. 517-09-9. Molecular formula: C18H18O2. Mole weight: 266.34. | |
| Equilenin Sulfate Sodium | A metabolite of Equilin. Equilenin is an estrogenic steroid hormone obtained from the urine of pregnant mares. Synonyms: 3-(Sulfooxy)-estra-1,3,5,7,9-pentaen-17-one Sodium Salt; 3-Hydroxyestra-1,3,5,7,9-pentaen-17-one HydrogenSulfate Monosodium Salt. Grades: > 95%. CAS No. 16680-48-1. Molecular formula: C18H17FO5S Na. Mole weight: 345.40 22.99. | |
| Equilin | Equilin is one of the estrogens present in the mixture of estrogens isolated from horse urine and marketed as Premarin. Uses: An estrogen. Synonyms: 3-Hydroxy-13-methyl-9,11,12,14,15,16-hexahydro-6H-cylcopenta(a)phenanthren-17-one. Grades: > 95%. CAS No. 474-86-2. Molecular formula: C18H20O2. Mole weight: 268.36. | |
| Equilin 3-Benzoate | Equilin 3-Benzoate is an intermediate of Equilin. Equilin is one of the estrogens present in the mixture of estrogens isolated from horse urine and marketed as Premarin. Synonyms: 3-(Benzoyloxy)-estra-1,3,5(10),7-tetraen-17-one; 3-Hydroxy-estra-1,3,5(10),7-tetraen-17-one Benzoate; Equilin benzoate; 17-Oxoestra-1,3,5(10),7-tetraen-3-yl benzoate; Estra-1,3,5(10),7-tetraen-17-one, 3-(benzoyloxy)-; Equilin Impurity 10. Grades: ≥95%. CAS No. 6030-80-4. Molecular formula: C25H24O3. Mole weight: 372.46. | |
| Equilin 3-Sulfate Sodium Salt | A derivative of Equilin. Equilin is one of the estrogens present in the mixture of estrogens isolated from horse urine and marketed as Premarin. Uses: Estrogens. Synonyms: 3-(Sulfooxy)estra-1,3,5(10),7-tetraen-17-one Sodium Salt; 3-Hydroxyestra-1,3,5(10),7-tetraen-17-one Hydrogen Sulfate Sodium Salt; Sodium Equilin 3-Monosulfate. Grades: > 95%. CAS No. 16680-47-0. Molecular formula: C18H19O5S. Na. Mole weight: 370.4. | |
| Erastin | Erastin is an antitumor agent selective for tumor cells bearing oncogenic RAS (i.e. HRAS, KRAS). Erastin produces non-apoptotic tumor cell death by altering mitochondrial voltage-dependent anion channel (VDAC) gating allowing cations to enter mitochondria and leading to release of oxidative species causing oxidative cell death. Erastin blocks and reverses mitochondrial depolarization after microtubule destabilizers in intact cells and antagonized tubulin-induced VDAC blockage in planar bilayers. Reversal of tubulin-VDAC interaction by erastin antagonizes Warburg metabolism and restores oxidative mitochondrial metabolism. Synonyms: Erastin. Grades: 0.98. CAS No. 571203-78-6. Molecular formula: C30H31ClN4O4. Mole weight: 547.04454. | |
| Erdosteine Homocysteine Impurity (Erdosteine RV201) | Erdosteine Homocysteine Impurity (Erdosteine RV201) is an impurity of the mucolytic Erdosteine. Synonyms: 2-[N-3-[2- (Oxotetrahydro) thienyl]acetimido]-N- (carboxymethylthioacetyl) homcysteine; [2- [ [2-Oxo-2- [ (tetrahydro-2-oxo-3-thienyl) amino] ethyl] thio] acetyl] homocysteine; Erdosteine RV 201; N-[ ({2-Oxo-2-[ (2-oxotetrahydro-3-thiophenyl) amino]ethyl}sulfanyl) acetyl]homocysteine; (2- ( (2-oxo-2- ( (2-oxotetrahydrothiophen-3-yl) amino) ethyl) thio) acetyl) homocysteine; Homocysteine, N-[2-[[2-oxo-2-[(tetrahydro-2-oxo-3-thienyl)amino]ethyl]thio]acetyl]-. Molecular formula: C12H18N2O5S3. Mole weight: 366.48. | |
| Erdosteine Thioacid Diammonium Salt | Erdosteine Thioacid Diammonium Salt is the active metabolite of Erdosteine. Erdosteine is a mucolytic. Synonyms: N-[[ (Carboxymethyl) thio]acetyl]homocysteine Diammonium Salt. Grades: 95%. Molecular formula: C8H19N3O5S2. Mole weight: 301.38. | |
| Erdosteine Thioacid Disodium Salt | Erdosteine Thioacid Disodium Salt is the active metabolite of Erdosteine, which is a mucolytic used in the treatment of excessive viscous mucus. Synonyms: N-[[ (Carboxymethyl) thio]acetyl]homocysteine Disodium Salt; [[2-Oxo-2-[ (1-carboxy-3-mercaptopropyl) amino]ethyl]thio]acetic acid Disodium Salt; Erdosteine Metabolite 1 Disodium Salt; Butanoic acid, 2-((((carboxymethyl)thio)acetyl)amino)-4-mercapto-, DL-, sodium salt (1:2); DL-2-((((Carboxymethyl)thio)acetyl)amino)-4-mercaptobutanoic acid Disodium Salt. Grades: 96%. CAS No. 254884-18-9. Molecular formula: C8H11NNa2O5S2. Mole weight: 311.29. | |
| Eritadenine Acetonide | Eritadenine Acetonide is an intermediate in the synthesis of Eritadenine, which is an inhibitor of S-adenosine-L-homocysteine hydrolase (SAHH) with hypocholesterolemic activity. Synonyms: (4R-cis)-5-[(6-Amino-9H-purin-9-yl)methyl]-2,2-dimethyl-1,3-dioxolane-4-carboxylic Acid; D-4-(6-Amino-9H-purin-9-yl)-4-deoxy-2,3-O-isopropylidene-erythronic Acid; 4-(6-Amino-9H-purin-9-yl)-4-deoxy-2,3-O-isopropylidene-D-erythronic Acid; 4-(6-Aminopurin-9-yl)-4-deoxy-2,3-O-isopropylidene-D-erythronic Acid; 1,3-Dioxolane-4-carboxylic acid, 5-[(6-amino-9H-purin-9-yl)methyl]-2,2-dimethyl-, (4R-cis)-. CAS No. 29031-25-2. Molecular formula: C12H15N5O4. Mole weight: 293.28. | |
| Erlotinib Carboxylic Acid | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: Erlotinib Metabolite M6; Erlotinib Acid. Grades: > 95%. Molecular formula: C22H25N3O6. Mole weight: 427.46. | |
| Erlotinib Hydroxy Metabolite | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: Hydroxy Erlotinib; N-(3-Ethynyl-4-hydroxy-phenyl)[6,7-bis(2-methoxyethoxy)quinazolin-4-yl] amine hydrochloride. Grades: > 95%. CAS No. 882420-22-6. Molecular formula: C22H23N3O5. Mole weight: 409.45. | |
| Erlotinib impurity 1 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: N-(3-(1-chlorovinyl)phenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine. Grades: > 95%. Molecular formula: C22H24ClN3O4. Mole weight: 429.91. | |
| Erlotinib Impurity 11 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: N'-[2-Cyano-4,5-bis(2-methoxyethoxy)phenyl]-N,N-dimethylimidoformamide. Grades: > 95%. CAS No. 950596-59-5. Molecular formula: C16H23N3O4. Mole weight: 321.38. | |
| Erlotinib Impurity 12 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: (E)-2-(((dimethylamino)methylene)amino)-4,5-bis(2-methoxyethoxy)benzamide. Grades: > 95%. Molecular formula: C16H25N3O5. Mole weight: 339.39. | |
Our database is helping our users find suppliers everyday.
