BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Fluvastatin Ketone Sodium Salt | Fluvastatin Ketone Sodium Salt is an eminent chemical compound extensively employed in developing therapeutic agent for dyslipidemia and hypercholesterolemia. Functioning as a potent HMG-CoA reductase inhibitor, it efficaciously restrains the intricate biosynthesis of cholesterol and concurrently diminishes the levels of LDL cholesterol. Grade: > 95%. Molecular formula: C24H25FNO4Na. Mole weight: 433.46. |  |
| Fluvastatin lactone-mixture of four isomers | Fluvastatin lactone-mixture of four isomers is the isomers from Fluvastatin lactone, a drug for unequivocally treating the onset of cardiovascular pathologies. Grade: > 95%. Molecular formula: C24H24FNO3. Mole weight: 393.46. | |
| Fluvastatin lactone (racemic mixture) | Fluvastatin lactone (racemic mixture) is an extensively applied compound employed for the research of dyslipidemia, a complex disorder specifically marked by the augmentation of cholesterol and triglyceride concentrations. This exceptional product aids in the inhibition of HMG-CoA reductase, subsequently leading to a decrease in cholesterol biosynthesand thus facilitating the effective control and research of hypercholesterolemia. Grade: > 95%. Molecular formula: C24H24FNO3. Mole weight: 393.46. | |
| Fluvastatin Methyl Ester | Fluvastatin Methyl Ester is an indispensable biomedical entity, demonstrating paramount significance in studying dyslipidemia. Through potent inhibition of HMG-CoA reductase, Fluvastatin Methyl Ester remarkably mitigates LDL cholesterol levels. Synonyms: AKOS015896075; AC-4521; (3R,5S,6E)-rel-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic Acid Methyl Ester; 786710-21-2; Methyl (3R,5S,E)-7-(3-(4-fluorophenyl)-1-isopropyl-1H-indol-2-yl)-3,5-dihydroxyhept-6-enoate. Grade: > 95%. CAS No. 786710-21-2. Molecular formula: C25H28FNO4. Mole weight: 425.50. | |
| Fluvastatin sodium salt | Fluvastatin Sodium inhibits HMG-CoA reductase activity with IC50 of 8 nM. Uses: Anticholesteremic agents; hydroxymethylglutaryl-coa reductase inhibitors. Synonyms: Canef; Fluindostatin; Lescol XL; Lipaxan; Vastin; XU-62-320; XU62320; XU 62 320. Grade: >98%. CAS No. 93957-55-2. Molecular formula: C24H25FNNaO4. Mole weight: 433.45. | |
| Fluvastatin Sodium Salt-mixture of four isomers | Fluvastatin Sodium Salt is a complex amalgamation of four distinct isomers exhibiting a profound and meticulous ability to selectively inhibit the enzyme 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. Grade: > 95%. Molecular formula: C24H25FNO4Na. Mole weight: 433.46. | |
| Fluvastatin t-Butyl Ester | Fluvastatin t-Butyl Ester is an intermediate for the preparation of (3R,5S)-Fluvastatin. Synonyms: tert-Butyl (E)-3,5-Dihydroxy-7-[3'-(4''-fluorophenyl)-1'-methylethylindol-2'-yl)hept-6-enoate; 7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid 1,1-dimethylethyl ester; (3R,5S)-Fluvastatin tert-Butyl Ester; (3R,5S,6E)-7-[. Grade: > 95%. CAS No. 194934-96-8. Molecular formula: C28H34FNO4. Mole weight: 467.59. | |
| Fluxametamide | Fluxametamide, a broad-spectrum insecticide, is an antagonist of GABA- and glutamate-gated chloride channels, with IC50s of 1.95 and 225 nM for M. domestica GABACls and GluCls. Synonyms: 4-(5-(3,5-Dichlorophenyl)-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl)-N-((methoxyimino)methyl)-2-methylbenzamide; Benzamide, 4-(5-(3,5-dichlorophenyl)-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl)-N-((methoxyamino)methylene)-2-methyl-; 4-[5-(3,5-Dichlorophenyl)-4,5-dihydro-5-(trifluoromethyl)-1,2-oxazol-3-yl]-N-[(methoxyimino)methyl]-o-toluamide. Grade: ≥98%. CAS No. 928783-29-3. Molecular formula: C20H16Cl2F3N3O3. Mole weight: 474.26. | |
| FMK | FMK is a potent, highly specific and irreversible ribosomal s6 kinase (RSK) inhibitor that covalently modifies the C-terminal kinase domain of RSK. Its IC50 value is 15 nM. It could prevent the activation of the N-terminal kinase domain of RSK by the C-terminal kinase domain, but does not affect the activity of the N-terminal domain. It binds in the CTKD ATP-binding site and inhibits RSK autophosphorylation at Ser386. It induces significant apoptosis in human FGFR3-expressing, t(4;14)-positive multiple myeloma cells. It is used to determine the role of RSK as a direct regulator of NHE1 phosphorylation and sarcolemmal NHE activity in this cell type, in response to 1-adrenergic stimulation. Uses: Fmk could prevent the activation of the n-terminal kinase domain of rsk by the c-terminal kinase domain, but does not affect the activity of the n-terminal domain. it is used to determine the role of rsk as a direct regulator of nhe1 phosphorylation and sarcolemmal nhe activity in this cell type, in response to 1-adrenergic stimulation. Synonyms: 1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-fluoroethanone; RSK2 kinase inhibitor. Grade: >98%. CAS No. 821794-92-7. Molecular formula: C18H19FN4O2. Mole weight: 342.37. | |
| FMK 9a | FMK 9a is a covalent autophagin-1 inhibitor (IC50 = 80 and 73 μM in FRET and LRA assay). Synonyms: FMK-9a; FMK 9a; FMK9a; N-[(2S)-1-[(3-fluoro-2-oxopropyl)amino]-1-oxo-3-phenylpropan-2-yl]naphthalene-1-carboxamide. CAS No. 1955550-51-2. Molecular formula: C23H21FN2O3. Mole weight: 392.42. | |
| FMK-MEA | FMK-MEA is a potent and selective p90 Ribosomal S6 Kinase (RSK) inhibitor. CAS No. 1414811-15-6. Molecular formula: C21H26FN5O2. Mole weight: 399.47. | |
| Fmoc-2,6-dimethyl-L-tyrosine | Fmoc-2,6-dimethyl-L-tyrosine, a derivative of tyrosine, is extensively utilized in peptide composite processes. In a myriad of studies, the peptide is known to be an effective building block in the assembly of bioactive peptides or proteins. Its application has been discovered in the realm of therapeutics too, working as a primary ingredient in drugs aiming to cure serious diseases such as cancer and neurological disorders. Synonyms: N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2,6-dimethyl-L-tyrosine; Fmoc-L-(2,6-di-Me)Tyr-OH; (S)-N-Fmoc-2,6-Dimethyltyrosine; L-Tyrosine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-2,6-dimethyl-; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-hydroxy-2,6-dimethylphenyl)propanoic acid. Grade: 97%. CAS No. 206060-54-0. Molecular formula: C26H25NO5. Mole weight: 431.48. | |
| Fmoc-3-(3'-Quinolyl)-L-Alanine | Fmoc-3-(3'-Quinolyl)-L-Alanine. Synonyms: Fmoc-Ala(3'-Quinolyl)-OH; Fmoc-L-Ala[3-(3-Quinolyl)]; (S)-alpha-(Fmoc-amino)-3-Quinolinepropanoic acid. CAS No. 281655-61-6. Molecular formula: C27H22N2O4. Mole weight: 438.47. | |
| Fmoc-3,4-dehydro-L-proline | Fmoc-3,4-dehydro-L-proline, a chemical intermediary employed in the synthesis of peptides within the biomedical sector, displays considerable promise with regard to the treatment of conditions such as cancer and Alzheimer's disease. Its potential medical applications are extensive and merit further exploration. Synonyms: Fmoc-3,4-dehydro-L-Pro-OH; (S)-Fmoc-3,4-dehydro-pyrrolidine-2-carboxylic acid. Grade: ≥ 98% (HPLC). CAS No. 135837-63-7. Molecular formula: C20H17NO4. Mole weight: 335.36. | |
| Fmoc-4-Borono-L-Phenylalanine | Fmoc-4-Borono-L-Phenylalanine, a derivative of amino acid utilized for peptide synthesis and asymmetric synthesis catalysis, has garnered significant interest due to its promising therapeutic effects on cancer and diabetes. Numerous studies have been conducted on this compound to explore its potential for treating these diseases. Synonyms: 4-(Dihydroxyboryl)-N-[(9H-fluoren-9-ylmethoxy)(hydroxy)methylene]-L-phenylalanine. CAS No. 273221-71-9. Molecular formula: C24H22BNO6. Mole weight: 431.2. | |
| Fmoc-Ala-Glu-Asn-Lys-NH2 | Fmoc-Ala-Glu-Asn-Lys-NH2 is a selective asparagine endopeptidase (AEP) inhibitor peptide and suppresses amyloid precursor protein (APP) cleavage. Synonyms: Fmoc-Ala-Glu-Asn-Lys-NH2; 220701-06-4; AKOS040756234; MS-31095; HY-114174; CS-0078435. Grade: 98%. CAS No. 220701-06-4. Molecular formula: C33H43N7O9. Mole weight: 681.74. | |
| Fmoc Amino-Modifier C6 dT | Fmoc Amino-Modifier C6 dT is renowned for its versatility, facilitating the synthesis of a wide range of compounds. It finds prominent utility in the modification of oligonucleotides for multifaceted applications such as drug delivery, gene therapy and the investigation of nucleic acid interactions. Synonyms: 5'-Dimethoxytrityl-5-[N-((9-fluorenylmethoxycarbonyl)-aminohexyl)-3-acrylimido]-2'-deoxyUridine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C63H73N6O11P. Mole weight: 1121.28. | |
| Fmoc-Arg(Pbf)-OH | Fmoc-Arg(Pbf)-OH is an amino acid derivative used in peptide synthesis. Synonyms: Fmoc-L-Arg(Pbf)-OH; Nα-Fmoc-Nω-(2,2,4,6,7-pentamethyldihydro-benzofuran-5-sulfonyl)-L-arginine; N5-[[[(2,3-Dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-ornithine. Grade: 98%. CAS No. 154445-77-9. Molecular formula: C34H40N4O7S. Mole weight: 648.77. | |
| Fmoc-β-Ala-Lys(Boc)-OH | Fmoc-β-Ala-Lys(Boc)-OH. Synonyms: (2S)-6-{[(tert-butoxy)carbonyl]amino}-2-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanamido]hexanoic acid; N2-(Fmoc-beta-alanyl)-N6-Boc-L-lysine. Grade: ≥ 95%. CAS No. 1998700-95-0. Molecular formula: C29H37N3O7. Mole weight: 539.62. | |
| Fmoc-Dha-OH | Fmoc-Dha-OH, a pivotal intermediate, is used for synthesizing a plethora of biologically active compounds encompassing antimicrobial peptides, dipeptidyl peptidase IV inhibitors, and enzyme inhibitors. Researchers have employed it to fabricate Fmoc-Dha-OH-derived peptidomimetics manifested by the impeding activity against a myriad of cancer cell lines. The said compound holds sheer potential for the design and development of novel pharmaceutical agents targeting numerous diseases. Synonyms: Fmoc-dehydro-Ala-OH; N-(9H-Fluorene-9-ylmethoxycarbonyl)-2,3-didehydro-L-alanine; 2-(((9H-fluoren-9-yl)methoxy)carbonylamino)acrylic acid. CAS No. 261522-33-2. Molecular formula: C18H15NO4. Mole weight: 309.3. | |
| Fmoc-D-Lys(Dde)-OH | Fmoc-D-Lys(Dde)-OH, a vital reagent for peptide synthesis, restricts the D-Lysine residue for selective introduction of D-amino acids into the peptide chains. Moreover, the Dde protection group enables mild deprotection under specific conditions during solid-phase synthesis, thus augmenting its applicability. This characteristic formulation, thus, serves as a fundamental component in the preparation of specialized peptides. Synonyms: Nα-Fmoc-Nε-1-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)ethyl-D-lysine; N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-epsilon-[(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)ethyl]-D-lysine; N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N6-(1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl)-D-lysine; N6-[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)ethyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-lysine. Grade: ≥99% by HPLC. CAS No. 333973-51-6. Molecular formula: C31H36N2O6. Mole weight: 532.63. | |
| Fmoc-(Dmb)Gly-OH | Fmoc-(Dmb)Gly-OH. Synonyms: Fmoc-N-(2,4-dimethoxybenzyl)-Gly-OH. Grade: 95%. CAS No. 166881-42-1. Molecular formula: C26H25NO6. Mole weight: 447.5. | |
| Fmoc-glycine | N-Fmoc-glycine is an N-Fmoc-protected form of Glycine. Glycine is a non-essential amino acid that acts as an inhibitory neyrotransmitter in the vertebrate central nervous system. Glycine also posesses cytoprotective effect against oxidant damage in the kidney. Synonyms: Fmoc-Gly-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]glycine; (((9H-Fluoren-9-yl)methoxy)carbonyl)glycine. Grade: 98%. CAS No. 29022-11-5. Molecular formula: C17H15NO4. Mole weight: 297.30. | |
| Fmoc-His-Aib-OH TFA | An intermediate in the synthesis of Semaglutide, an agonist of glucagon-like peptide-1 (GLP-1) receptor that is developed to treat type 2 diabetes. Grade: ≥98%. CAS No. 1446013-08-6. Molecular formula: C25H26N4O5.C2HF3O2. Mole weight: 576.53. | |
| Fmoc-L-Lys[C20-OtBu-Glu(OtBu)-AEEA-AEEA]-OH | Fmoc-L-Lys[C20-OtBu-Glu(OtBu)-AEEA-AEEA]-OH is a yellowish medical intermediate in the synthesis of Tirzepatide. Tirzepatide is a dual GIP and GLP-1 receptor agonist and a drug candidate for the treatment of type 2 diabetes. Synonyms: Fmoc-Lys(tBuO-Ara-Glu(AEEA-AEEA)-OtBu)-OH. Grade: 98%. CAS No. 2460751-66-8. Molecular formula: C66H105N5O16. Mole weight: 1224.59. | |
| Fmoc-L-Lys(Mca)-OH | Fmoc-L-Lys(Mca)-OH. Synonyms: N-α-(9-Fluorenylmethoxycarbonyl)-N-ε-[(7-methoxycoumarin-4-yl)acetyl]-L-lysine; (S)-2-(N-(((9H-fluoren-9-yl)methyl9H-fluoren-9-yl)methoxy)carbonyl)acetamido)-6-(7-methoxy-2-oxo-2H-chromen-4-ylamino)hexanoic acid; Nα-Fmoc-Nε-7-methoxycoumarin-4-acetyl-L-lysine; Fmoc-L-Lys(Mca)-OH. Grade: 98%. CAS No. 386213-32-7. Molecular formula: C33H32N2O8. Mole weight: 584.63. | |
| Fmoc-N-amido-PEG2-acetic acid | Fmoc-AEEA-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Synonyms: Fmoc-NH-PEG2-CH2COOH; Fmoc-8-amino-3,6-dioxaoctanoic acid; [2-[2-(Fmoc-amino)ethoxy]ethoxy]acetic acid; FMOC-AEEA; 12- (9H- Fluoren- 9- yl) - 10- oxo-3, 6, 11- trioxa- 9- azadodecanoic Acid; 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10-trioxa-4-azadodecan-12-oic Acid; 8-(9-Fluorenylmethoxycarbonylamino)-3,6-dioxaoctanoic Acid; 9-Fluorenylmethoxycarbonyl-8-amino-3,6-dioxaoctanoic Acid; 2,7,10-Trioxa-4-azadodecan-12-oic acid, 1-(9H-fluoren-9-yl)-3-oxo-. Grade: 98%. CAS No. 166108-71-0. Molecular formula: C21H23NO6. Mole weight: 385.41. | |
| Fmoc-N-Me-3-(4-py)-L-Ala | Fmoc-N-Me-3-(4-py)-L-Ala, a synthetic molecule, finds widespread use in the synthesis of peptides and proteins. Owing to its crucial role as a fundamental building block in solid-phase peptide synthesis, it has emerged as a potent weapon in the battle against numerous human maladies such as cancer and infectious diseases. With versatile functionality and chemical reactivity, the compound facilitates modifications and attachment to the peptide chain, rendering it a prized asset in the biomedical industry and a tool much sought after by researchers. Synonyms: Fmoc-N(Me)4Pal-OH; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-3-(pyridin-4-yl)propanoic acid. CAS No. 2381854-90-4. Molecular formula: C24H22N2O4. Mole weight: 402.4. | |
| Fmoc-N-Me-Asn(Trt)-OH | Fmoc-N-Me-Asn(Trt)-OH is an asparagine derivative. Synonyms: N-α-(9-Fluorenylmethoxycarbonyl)-N-α-methyl-N-β-trityl-L-asparagine; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-4-oxo-4-(tritylamino)butanoic acid. Grade: 98%. CAS No. 941296-80-6. Molecular formula: C39H34N2O5. Mole weight: 610.72. | |
| Fmoc-N-Me-Dab(Boc)-OH | Fmoc-N-Me-Dab(Boc)-OH, a peptide derivative, finds extensive applications in the pharmaceutical and biologically active compound synthesis arena. One can leverage it as a fundamental building block to engineer peptide-based drugs with proven anti-tumor activity. The versatility of Fmoc-N-Me-Dab(Boc)-OH renders it an indispensable tool in the scientific community, and its intricate molecular structure continues to inspire novel applications in the field of drug discovery and development. Synonyms: (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-4-((tert-butoxycarbonyl)amino)butanoic acid. CAS No. 2044702-38-5. Molecular formula: C25H30N2O6. Mole weight: 454.5. | |
| Fmoc-N-Me-D-Lys(Boc)-OH | Fmoc-N-Me-D-Lys(Boc)-OH is a multifaceted chemical agent that is employed in the synthetic production of proteins and peptides. This chemical is highly valued in the medical industry for its efficacy in treating infectious diseases and cancers. Scientists have also harnessed its potential for biochemical research pertaining to the design of pharmaceuticals directed towards targeted proteins. Synonyms: Fmoc-D-N(Me)Lys(Boc)-OH. CAS No. 1793105-27-7. Molecular formula: C27H34N2O6. Mole weight: 482.6. | |
| Fmoc-O-tert-butyl-L-tyrosine | Fmoc-O-tert-butyl-L-tyrosine is an amino acid protection monomer used in peptide synthesis. Synonyms: Fmoc-L-Tyr(tBu)-OH; Fmoc-Tyr(tBu)-OH; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(tert-butoxy)phenyl)propanoic acid; N-Fmoc-O-tert-butyl-L-tyrosine; Nalpha-Fmoc-O-tert-butyl-L-tyrosine. Grade: 98%. CAS No. 71989-38-3. Molecular formula: C28H29NO5. Mole weight: 459.53. | |
| Fmoc-Pal-Linker | It is a reagent for the mild solid-phase synthesis of C-terminal peptide amides. Synonyms: Pal Linker; Fmoc-Pal-Linker; 5-(4-(9-Fluorenylmethyloxycarbonyl)Aminomethyl-3,5-Dimethoxyphenoxy)Valeric Acid; 5-[3,5-Dimethoxy-4-(Fmoc-Aminomethyl)Phenoxy]Pentanoic Acid; 5-(4-(((((9H-Fluoren-9-Yl)Methoxy)Carbonyl)Amino)Methyl)-3,5-Dimethoxyphenoxy)Pentanoic Acid. Grade: ≥ 95% (HPLC). CAS No. 115109-65-4. Molecular formula: C29H31NO7. Mole weight: 505.5. | |
| Fmoc-Phe-Gly-OH | Fmoc-Phe-Gly-OH. Synonyms: Glycine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-phenylalanyl-; Fmoc-Phenylalanyl-glycine. Grade: ≥ 98% (HPLC). CAS No. 169624-67-3. Molecular formula: C26H24N2O5. Mole weight: 444.49. | |
| Fmoc-PNA-A(Bhoc)-OH | A Fmoc PNA monomer that is a building block for the synthesis of PNA oligomers. Uses: Fmoc-pna-a(bhoc)-oh is an fmoc pna monomer containing an fmoc (9-fluorenylmethoxycarbonyl) group for solid phase peptide synthesis and a bhoc (benzhydryloxycarbonyl) protecting group for specific applications. 1. solid phase peptide synthesis (spps): the solid phase synthesis of pna oligomers is one of the primary uses of fmoc-pna-a(bhoc)-oh. stepwise assembly of pna sequences on a solid support. Synonyms: 2-[[2-[6-[[(diphenylmethyl)oxy-oxomethyl]amino]-9-purinyl]-1-oxoethyl]-[2-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]ethyl]amino]acetic acid; 2-[[2-[6-(benzhydryloxycarbonylamino)purin-9-yl]acetyl]-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethyl]amino]acetic acid. Grade: 98%. CAS No. 186046-82-2. Molecular formula: C40H35N7O7. Mole weight: 725.7. | |
| Fmoc-PNA-C(Bhoc)-OH | A Fmoc PNA monomer that is a building block for the synthesis of PNA oligomers. Synonyms: 2-[[2-[4-[[(diphenylmethyl)oxy-oxomethyl]amino]-2-oxo-1-pyrimidinyl]-1-oxoethyl]-[2-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]ethyl]amino]acetic acid; 2-[[2-[4-(benzhydryloxycarbonylamino)-2-oxopyrimidin-1-yl]acetyl]-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethyl]amino]acetic acid. Grade: 98%. CAS No. 186046-81-1. Molecular formula: C39H35N5O8. Mole weight: 701.7. | |
| Fmoc-PNA-G(Bhoc)-OH | A Fmoc PNA monomer that is a building block for the synthesis of PNA oligomers. Synonyms: 2-[N-[2-(Fmoc-amino)ethyl]-2-[2-[[(benzhydryloxy)carbonyl]amino]-6-oxo-1H-purin-9(6H)-yl]acetamido]acetic Acid. Grade: 98%. CAS No. 186046-83-3. Molecular formula: C40H35N7O8. Mole weight: 741.76. | |
| Fmoc-PNA-thioU(PMB)-OH | Fmoc-PNA-thioU(PMB)-OH. Synonyms: N-(2-Fmoc-aminoethyl)-N-[2-[2-(4-methoxybenzylthio)-4-oxopyrimidin-1(1H)-yl]acetyl]glycine; Glycine, N-[2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]ethyl]-N-[2-[2-[[(4-methoxyphenyl)methyl]thio]-4-oxo-1(4H)-pyrimidinyl]acetyl]-. Grade: 95%. CAS No. 2245800-85-3. Molecular formula: C33H32N4O7S. Mole weight: 628.69. | |
| Fmoc-PNA-T-OH | A Fmoc PNA monomer that is a building block for the synthesis of PNA oligomers. Synonyms: Fmoc PNA T OH. Grade: 98%. CAS No. 169396-92-3. Molecular formula: C26H26N4O7. Mole weight: 506.5. | |
| Fmoc-Ser(Ac3AcNH-α-Glc)-OH | Fmoc-Ser(Ac3AcNH-α-Glc)-OH is a glycosylated serine derivative used in the synthesis of glycopeptides. The Fmoc group protects the amino group of serine, while the attached α-glucose molecule, modified with three acetyl groups and an N-acetyl group, provides a specific glycosylation pattern. This compound is valuable in biochemical and pharmaceutical research for creating glycosylated peptides, which are important for studying protein-carbohydrate interactions, enhancing peptide stability, and improving therapeutic properties. Synonyms: N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-α-D-glucopyranosyl]-L-serine; Fmoc-Ser(GlcNAc(Ac)-α-D)-OH; (Fmoc-L-Ser(α-D-GlcNAc(Ac)3)-OH); N-Fmoc-O-(2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-α-D-glucopyranosyl)-L-serine; N-(((9H-fluoren-9-yl)methoxy)carbonyl)-O-((2S,3R,4R,5S,6R)-3-acetamido-4,5-diacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-yl)-L-serine. Grade: ≥95%. CAS No. 172325-15-4. Molecular formula: C32H36N2O13. Mole weight: 656.64. | |
| Fmoc-Ser(tBu)-Ser(tBu)-OH | Fmoc-Ser(tBu)-Ser(tBu)-OH is a protected dipeptide used in peptide synthesis. It features an Fmoc (Fluorenylmethyloxycarbonyl) group at the N-terminus, which protects the amino group during synthesis. Each Ser (Serine) residue is protected by a tBu (tert-butyl) group at the hydroxyl side chain, preventing unwanted side reactions. The -OH at the C-terminus indicates a free carboxyl group, allowing the dipeptide to be coupled with other amino acids. This compound is used to incorporate serine residues into peptides while maintaining the integrity of the hydroxyl groups for selective deprotection later in the synthesis process. Synonyms: N-(Fluorenylmethoxycarbonyl)-O-tert-butyl-L-seryl-O-tert-butyl-L-serine; (S)-2-((S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(tert-butoxy)propanamido)-3-(tert-butoxy)propanoic acid; L-Serine, O-(1,1-dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-seryl-O-(1,1-dimethylethyl)-; L-Serine, O-(1,1-dimethylethyl)-N-[O-(1,1-dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-seryl]-; N-(N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-O-(tert-butyl)-L-seryl)-O-(tert-butyl)-L-serine; O-(1,1-Dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-seryl-O-(1,1-dimethylethyl)-L-serine; PSM-SS-1; SS; Fmoc-Ser(OtBu)-Ser(OtBu)-OH. Grade: ≥95%. CAS No. 110098-50-5. Molecular formula: C29H38N2O7. Mole weight: 526.62. | |
| Fmoc-trans-4-methyl-L-Pro-OH | Fmoc-trans-4-methyl-L-Pro-OH. Synonyms: N-(9-Fluorenylmethoxycarbonyl)-(2S,4R)-4-methylproline; 1-(9H-Fluorene-9-ylmethoxycarbonyl)-4beta-methyl-L-proline; Fmoc-trans-4-Amc-OH; Fmoc-trans-4-methyl-L-proline; (2S,4R)-Fmoc-4-Methyl-L-Pro-OH; (4R)-1-[(9H-Fluoren-9-ylmethoxy)carbonyl]-4-methyl-L-proline; 1,2-Pyrrolidinedicarboxylic acid, 4-methyl-, 1-(9H-fluoren-9-ylmethyl) ester, (2S,4R)-. Grade: 98% by HPLC. CAS No. 333777-34-7. Molecular formula: C21H21NO4. Mole weight: 351.39. | |
| Fmoc-Val-Ala-OH | Fmoc-Val-Ala-OH is a widely used cleavable peptide linker that can conveniently serve as a building block for the careful construction of peptide-directed therapeutics and pharmaceuticals. Its multifaceted nature holds great promise in combating a range of diseases, including but not limited to neoplastic diseases, autoimmune diseases, and potential infections. Synonyms: (S)-2-((S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-methylbutanamido)propanoic acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-valyl-L-alanine. Grade: ≥ 95%. CAS No. 150114-97-9. Molecular formula: C23H26N2O5. Mole weight: 410.46. | |
| Fmoc-Val-Cit-PAB | Fmoc-Val-Cit-PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Synonyms: Fmoc-Val-Cit-PAB-OH; L-Ornithinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-. CAS No. 159858-22-7. Molecular formula: C33H39N5O6. Mole weight: 601.70. | |
| Fmoc-Val-Cit-PAB-PNP | Fmoc-Val-Cit-PAB-PNP. Synonyms: N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-valyl-N5-carbamoyl-N-[4-({[(4-nitrophenoxy)carbonyl]oxy}methyl)phenyl]-L-ornithinamide. Grade: ≥98%. CAS No. 863971-53-3. Molecular formula: C40H42N6O10. Mole weight: 766.79. | |
| FN-1501 | FN-1501 is a potent FLT3 and CDK inhibitor, with IC50s of 2.47, 0.85, 1.96, and 0.28 nM for CDK2/cyclin A, CDK4/cyclin D1, CDK6/cyclin D1 and FLT3, respectively. It has anticancer activity. Synonyms: 4-((7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-N-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-1H-pyrazole-5-carboxamide; 1H-Pyrazole-3-carboxamide, N-[4-[(4-methyl-1-piperazinyl)methyl]phenyl]-4-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-; N-{4-[(4-Methyl-1-piperazinyl)methyl]phenyl}-4-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1H-pyrazole-3-carboxamide. Grade: ≥98%. CAS No. 1429515-59-2. Molecular formula: C22H25N9O. Mole weight: 431.49. | |
| FN-1501-propionic acid | FN-1501-propionic acid is a CDK2/9 ligand for PROTAC. FN-1501-propionic acid and a CRBN ligand have been used to design PROTAC CDK2/9 degrader. Synonyms: 4-Oxo-4-{4-[4-({[4-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1H-pyrazol-3-yl]carbonyl}amino)benzyl]-1-piperazinyl}butanoic acid; 1-Piperazinebutanoic acid, γ-oxo-4-[[4-[[[4-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1H-pyrazol-3-yl]carbonyl]amino]phenyl]methyl]-. Grade: ≥95%. CAS No. 2408642-48-6. Molecular formula: C25H27N9O4. Mole weight: 517.54. | |
| FNC-TP | FNC-TP is the intracellular active form of FNC which is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV. Synonyms: RO-0622-TP. Grade: 99%. CAS No. 2457357-99-0. Molecular formula: C9H14FN6O13P3. Mole weight: 526.16. | |
| FNC-TP trisodium | FNC-TP trisodium is the intracellular active form of FNC which is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV. Molecular formula: C9H11FN6Na3O13P3. Mole weight: 592.11. | |
| FNDR-20123 | FNDR-20123 is a first-in-class, and orally active anti-malarial HDAC inhibitor with IC50s of 31 nM and 3 nM for Plasmodium and human HDAC, respectively. FNDR-20123 exerts anti-malarial activity against Plasmodium falciparum asexual stage (IC50 = 41 nM) and sexual blood stage (IC50 = 190 nM for male gametocytes). Grade: 98%. Molecular formula: C21H24ClN5O2. Mole weight: 413.90. | |
| FNDR-20123 free base | FNDR-20123 is a first-in-class, and orally active anti-malarial HDAC inhibitor with IC50s of 31 nM and 3 nM for Plasmodium and human HDAC, respectively. FNDR-20123 exerts anti-malarial activity against Plasmodium falciparum asexual stage (IC50 = 41 nM) and sexual blood stage (IC50 = 190 nM for male gametocytes). CAS No. 1267502-34-0. Molecular formula: C21H23N5O2. Mole weight: 377.44. | |
| Fobrepodacin | Fobrepodacin is an orally active and potent phosphate prodrug of SPR719 and has potent bactericidal activities in vivo. Synonyms: 2-(5-{2-[(ethylcarbamoyl)amino]-6-fluoro-7-[(2R)-oxolan-2-yl]-1H-benzimidazol-5-yl}pyrimidin-2-yl)propan-2-yl dihydrogen phosphate; N-Ethyl-N'-(6-fluoro-5-(2-(1-methyl-1-(phosphonooxy)ethyl)-5-pyrimidinyl)-7-((2R)-tetrahydro-2-furanyl)-1H-benzimidazol-2-yl)urea; SPR720; SPR-720; SPR 720; pVXc-486; pVXc 486; pVXc486; (R)-2-(5-(2-(3-ethylureido)-6-fluoro-7-(tetrahydrofuran-2-yl)-1H-benzo[d]imidazol-5-yl)pyrimidin-2-yl)propan-2-yl dihydrogen phosphate. Grade: ≥98%. CAS No. 1384984-31-9. Molecular formula: C21H26FN6O6P. Mole weight: 508.44. | |
| Fobrepodacin disodium | Fobrepodacin is an orally active and potent phosphate prodrug of SPR719 and has potent bactericidal activities in vivo. Synonyms: VXC-486 phosphate disodium; Urea, N-ethyl-N'-(6-fluoro-5-(2-(1-methyl-1-(phosphonooxy)ethyl)-5-pyrimidinyl)-7-((2R)-tetrahydro-2-furanyl)-1H-benzimidazol-2-yl)-, sodium salt (1:2); SPR720 disodium. CAS No. 1384984-20-6. Molecular formula: C21H24FN6Na2O6P. Mole weight: 552.40. | |
| Folcysteine | Folcysteine, a vitamin, is a cysteine derivative that acts as a potential antitumor agent. Synonyms: N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-Glutamic Acid Mixture With (4R)-3-Acetyl-4-thiazolidinecarboxylic Acid; N-[4-[[(2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-Glutamic acid Mixture With (R)-3-Acetyl-4-thiazolidinecarboxylic Acid; Ergostim; FOP; Folcysteine FOP. Grade: 96%. CAS No. 8064-47-9. Molecular formula: C25H28N8O9S. Mole weight: 616.60. | |
| Folic acid | Folic acid is a vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA, and it also acts as a cofactor in biological reactions involving folate. The combined use of enalapril and folic acid, compared with enalapril alone, significantly reduced the risk of first stroke. High folic acid intakes and MTHFR gene variations seem not to be associated with helping women to achieve pregnancy during or after fertility treatment. Uses: Hematopoietic vitamin. Synonyms: n-4-[(2-amido-4-oxo-1,4-dihydro-6-terene)methylamino]benzoyl-l-glutamic acid. Grade: >98%. CAS No. 59-30-3. Molecular formula: C19H19N7O6. Mole weight: 441.40. | |
| Folic Acid Dihydrate | Folic Acid Dihydrate is the hydrate form of Folic acid, which is used to treat anemia caused by folate deficiency. Synonyms: (S)-2-(4-(((2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl)amino)benzamido)pentanedioic acid dihydrate; L-Glutamic acid, N-(4-(((2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-, hydrate (1:2); N-(4-{[(2-Amino-4-oxo-1,4-dihydro-6-pteridinyl)methyl]amino}benzoyl)-L-glutamic acid dihydrate. Grade: ≥95%. CAS No. 75708-92-8. Molecular formula: C19H19N7O6. Mole weight: 477.43. | |
| Folic Acid EP Impurity A (Methotrexate EP Impurity K) | An impurity of Methotrexate, an antimetabolite and immunosuppressant used in chemotherapy and auto-immune diseases. Synonyms: 4-Aminobenzoylglutamic Acid (USP); N-(4-Aminobenzoyl)-L-glutamic Acid; N-(p-Aminobenzoyl)glutamic Acid; N-(p-Aminobenzoyl)-L(+)-glutamic Acid. Grade: > 95%. CAS No. 4271-30-1. Molecular formula: C12H14N2O5. Mole weight: 266.25. | |
| Folic Acid EP Impurity B | One of the impurities of Folic acid. Folic acid is a vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA, and it also acts as a cofactor in biological reactions involving folate. Synonyms: 6-Hydroxy-2,4,5-triaminopyrimidine; 2,5,6-Triaminopyrimidin-4(3H)-one; 2,5,6-Triamino-4(1H)-pyrimidinone. Grade: 97%. CAS No. 1004-75-7. Molecular formula: C4H7N5O. Mole weight: 141.13. | |
| Folic Acid EP Impurity C | Folic Acid EP Impurity C is the isomer of Folic acid, which is used to treat anemia caused by folate deficiency. Uses: The 7-isomer of pteroylglutamic acid. Synonyms: Isofolic acid; N-[4-[[(2-Amino-1,4-dihydro-4-oxo-7-pteridinyl)methyl]amino]benzoyl]-L-glutamic Acid; N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)amino)methyl)benzoyl)glutamic acid. Grade: ≥95%. CAS No. 47707-78-8. Molecular formula: C19H19N7O6. Mole weight: 441.40. | |
| Folic Acid EP Impurity D (Methotrexate EP Impurity D) | Pteroic Acid is one of methotrexate impurities. Methotrexate is a folic acid antagonist, used as an antineoplastic and antirheumatic. Synonyms: Pteroic acid; Pyrofolic acid; p-[(2-Amino-4-hydroxy-6-pteridylmethyl)amino]benzoic Acid. Grade: > 85 %. CAS No. 119-24-4. Molecular formula: C14H12N6O3. Mole weight: 312.28. | |
| Folic Acid EP Impurity E | One of the impurities of Folic acid. Folic acid is a vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA, and it also acts as a cofactor in biological reactions involving folate. Synonyms: 6-Pterinyl Folic Acid; N-[4-[Bis[(2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid. Grade: 95%. CAS No. 1391068-26-0. Molecular formula: C26H24N12O7. Mole weight: 616.55. | |
| Folic Acid EP Impurity F | One of the impurities of Folic acid. Folic acid is a vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA, and it also acts as a cofactor in biological reactions involving folate. Synonyms: 2-Amino-7-(chloromethyl)pteridin-4(1H)-one. CAS No. 1391194-56-1. Molecular formula: C7H6ClN5O. Mole weight: 211.61. | |
| Folic acid hydrate EP Impurity G | One of the impurities of Folic acid. Folic acid is a vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA, and it also acts as a cofactor in biological reactions involving folate. Synonyms: (S)-2-(4-((2-Amino-7-methyl-4-oxo-1,4-dihydropteridin-6-yl)amino)benzamido)pentanedioic acid; N-[4-[(2-Amino-3,4-dihydro-7-methyl-4-oxo-6-pteridinyl)amino]benzoyl]-L-glutamic acid. Grade: 95%. CAS No. 2734707-85-6. Molecular formula: C19H19N7O6. Mole weight: 441.40. | |
| Folic Acid Hydrate EP Impurity H | One of the impurities of Folic acid. Folic acid is a vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA, and it also acts as a cofactor in biological reactions involving folate. Synonyms: N-[4-[[N-[4-[[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino]benzoyl]-L-γ-glutamyl]amino]benzoyl]-L-glutamic Acid. CAS No. 2366274-27-1. Molecular formula: C31H31N9O10. Mole weight: 689.64. | |
| Foliglurax | Foliglurax, also known as PXT002331, is a highly selective and potent, brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) with an EC50 of 79 nM. The metabotropic glutamate receptor 4 (mGluR4) is an emerging target for the treatment of Parkinson's disease (PD). Synonyms: (E)-6-(3-morpholinopropyl)-2-(thieno[3,2-c]pyridin-6-yl)-4H-chromen-4-one oxime; PXT002331. CAS No. 1883329-51-8. Molecular formula: C23H23N3O3S. Mole weight: 421.52. | |
| Foliglurax monohydrochloride | Foliglurax, also known as PXT002331, is a highly selective and potent, brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) with an EC50 of 79 nM. The metabotropic glutamate receptor 4 (mGluR4) is an emerging target for the treatment of Parkinson's disease (PD). Synonyms: Foliglurax (monohydrochloride); PXT002331 (monohydrochloride). Grade: 98%. CAS No. 2133294-96-7. Molecular formula: C23H24ClN3O3S. Mole weight: 457.97. | |
| Folinic acid | Folinic acid is an adjuvant used in cancer chemotherapy involving the drug methotrexate. It is a 5-formyl derivative of tetrahydrofolic acid and readily converted to other reduced folic acid derivatives, thus, has vitamin activity that is equivalent to that of folic acid. Since it does not require the action of dihydrofolate reductase for its conversion, its function as a vitamin is unaffected by inhibition of this enzyme by drugs such as methotrexate. Synonyms: leucovorin. Grade: >98%. CAS No. 58-05-9. Molecular formula: C20H23N7O7. Mole weight: 473.44. | |
| Folitixorin Calcium | Folitixorin Calcium is a medication undergoing phase III clinical trials for the treatment of colorectal cancer and phase II clinical trials for advanced pancreatic cancer. Synonyms: Cofactor; ANX-510; ANX 510; ANX510. Grade: ≥95%. CAS No. 133978-75-3. Molecular formula: C20H21CaN7O6. Mole weight: 495.51. | |
| Fomepizole | 4-Methylpyrazole is a competitive inhibitor of alcohol dehydrogenase, which catalyzes metabolism of ethylene glycol and methanol to toxic metabolites. It is used as an antidote for ethylene glycol or methanol poisoning. It may be used alone or in combination with hemodialysis. It can prevent the formation of toxic alcohol metabolites that generate metabolic acidosis at 10 μM in monkeys. It also inhibits CYP2E1 activity. It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system. Uses: 4-methylpyrazole is used as an antidote for ethylene glycol or methanol poisoning. it also inhibits cyp2e1 activity. Synonyms: 4-methyl-1H-pyrazole. Grade: 98 %. CAS No. 7554-65-6. Molecular formula: C4H6N2. Mole weight: 82.10. | |
| Fomesafen | Fomesafen is a protoporphyrinogen oxidae (PPO) inhibitor. Synonyms: Fomesafene; 5-(2-Chloro-4-(trifluoromethyl)phenoxy)-N-(methylsulfonyl)-2-nitrobenzamide; Reflex. Grade: 95%. CAS No. 72178-02-0. Molecular formula: C15H10ClF3N2O6S. Mole weight: 438.76. | |
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