BOC Sciences 8 - Products

BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.

Product
Mianserin Hydrochloride Mianserin Hydrochloride is a psychoactive drug of the tetracyclic antidepressant.It is classified as a noradrenergic and specific serotonergic antidepressant (NaSSA) and has antidepressant, anxiolytic (anti-anxiety), hypnotic (sedating), antiemetic (nausea and vomiting-attenuating), orexigenic (appetite-stimulating), and antihistamine effects.It is not approved for use in the US. Uses: Antidepressive agents, second-generation. Synonyms: ORG GB-94 HCl; Mianserin hydrochloride; Tolvon; Tolvin; ORG GB 94; Lerivon. Grades: >98%. CAS No. 21535-47-7. Molecular formula: C18H20N2.HCl. Mole weight: 300.83. BOC Sciences 8
Mibefradil dihydrochloride The dihydrochloride hydrate salt form of Mibefradil which is a calcium channel blocker with modest selectivity for T-type Ca2+ channels so that it could be used in the treatment of sorts of cardiovascular disease like hypertension and chronic angina pectoris. Uses: Antihypertensive agents. Synonyms: Mibefradil 2HCl; [(1S,2S)-2-[2-[3-(1H-benzimidazol-2-yl)propyl-methylamino]ethyl]-6-fluoro-1-propan-2-yl-3,4-dihydro-1H-naphthalen-2-yl] 2-methoxyacetate dihydrochloride. Grades: 95%. CAS No. 116666-63-8. Molecular formula: C29H40Cl2FN3O3. Mole weight: 568.55. BOC Sciences 8
Micafungin Impurity 3 Micafungin Impurity 3 is an impurity of Micafungin, it is used to optimize the side chain of the natural product FR901379. Synonyms: 4-(5-(4-(Pentyloxy)phenyl)isoxazol-3-yl)benzoic acid; Benzoic acid, 4-[5-[4-(pentyloxy)phenyl]-3-isoxazolyl]-; 4-[5-(4-pentyloxyphenyl)isoxazol-3-yl]benzoic acid; 4-[5-(4-pentoxyphenyl)-1,2-oxazol-3-yl]benzoic Acid; 4-{5-[4-(Pentyloxy)phenyl]isoxazol-3-yl}benzoic acid; SCHEMBL2353533; PDTXSIGPZDVVIX-UHFFFAOYSA-N; MFCD20267356; AKOS025395935; DS-8489; SB18167; AM20090710; CS-0160970; F52834; A924886; A1-01692; 4-(5-(4-(Pentyloxy)phenyl)isoxazol-3-yl)benzoicacid; 4-[5-(4-n-pentyloxyphenyl)isoxazol-3-yl]benzoic acid; 4-(5-{4-[(Pent-1-yl)oxy]phenyl}isoxazol-3-yl)benzoic acid; 4-{5-[4-(PENTYLOXY)PHENYL]-1,2-OXAZOL-3-YL}BENZOIC ACID; 4-{5-[4-(Pentyloxy)phenyl]-1,2-oxazol-3-yl}benzoic acid, 3-(4-Carboxyphenyl)-5-[4-(pentyloxy)phenyl]-1,2-oxazole. Grades: > 95%. CAS No. 179162-55-1. Molecular formula: C21H21NO4. Mole weight: 351.4. BOC Sciences 8
Micafungin Impurity A BOC Sciences 8
Micafungin Impurity B BOC Sciences 8
Micafungin Impurity D BOC Sciences 8
Micafungin Impurity E Micafungin Impurity E is an impurity of Micafungin, an echinocandin antifungal drug used for the treatment of invasive fungal infections including candidiasis, candidemia and esophageal candidiasis. Micafungin inhibits the synthesis of 1,3-β-D-glucan, an essential component of the fungal cell wall, and represent a valuable treatment option for fungal infections. Molecular formula: C56H70N9NaO22S. Mole weight: 1276.25. BOC Sciences 8
Micafungin Sodium Stereoisomer Micafungin Impurity H is an impurity of Micafungin, an echinocandin antifungal drug used for the treatment of invasive fungal infections including candidiasis, candidemia and esophageal candidiasis. Micafungin inhibits the synthesis of 1,3-β-D-glucan, an essential component of the fungal cell wall, and represent a valuable treatment option for fungal infections. Synonyms: 1H-Dipyrrolo[2, 1-c:2', 1'-l][1, 4, 7, 10, 13, 16]hexaazacycloheneicosine-20-propanamide, 23-[ (1S, 2S) -1, 2-dihydroxy-2-[4-hydroxy-3- (sulfooxy) phenyl]ethyl]tetracosahydro-β , 2, 11, 12, 15-pentahydroxy-6-[ (1R) -1-hydroxyethyl]-16-methyl-5, 8, 14, 19, 22, 25-hexaoxo-9-[[4-[3-[4- (pentyloxy) phenyl]-5-isoxazolyl]benzoyl]amino]-, (βR, 2R, 6S, 9S, 11R, 12R, 14aS, 15S, 16S, 20S, 23S, 25aS)-, sodium salt (1:1); (β R, 2R, 6S, 9S, 11R, 12R, 14aS, 15S, 16S, 20S, 23S, 25aS) -23-[ (1S, 2S) -1, 2-Dihydroxy-2-[4-hydroxy-3- (sulfooxy) phenyl]ethyl]tetracosahydro-β , 2, 11, 12, 15-pentahydroxy-6-[ (1R) -1-hydroxyethyl]-16-methyl-5, 8, 14, 19, 22, 25-hexaoxo-9-[[4-[3-[4- (pentyloxy) phenyl]-5-isoxazolyl]benzoyl]amino]-1H-dipyrrolo[2, 1-c: 2', 1'-l][1, 4, 7, 10, 13, 16]hexaazacycloheneicosine-20-propanamide sodium salt. CAS No. 1686155-92-9. Molecular formula: C56H70N9NaO23S. Mole weight: 1292.25. BOC Sciences 8
Milataxel Milataxel is an orally bioavailable taxane with potential antineoplastic activity. Upon oral administration, milataxel and its major active metabolite M-10 bind to and stabilize tubulin, resulting in the inhibition of microtubule depolymerization and cell division, cell cycle arrest in the G2/M phase, and the inhibition of tumor cell proliferation. Unlike other taxane compounds, milataxel appears to be a poor substrate for the multidrug resistance (MDR) membrane-associated P-glycoprotein (P-gp) efflux pump and may be useful for treating multidrug-resistant tumors. Synonyms: (αR,βR)β-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-hydroxy-2-furanpropanoic acid, (2aR,4S,4aS,6R,9S,11S,12S,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-6,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-(1-oxopropoxy)-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester; MAC 321; 1,10beta-Dihydroxy-9-oxo-5beta,20-epoxy-3zeta-tax-11-ene-2alpha,4,7beta,13alpha-tetrayl 4-acetate 2-benzoate 13-((2R,3R)-3-(tert-butoxycarbonylamino)-3-(furan-2-yl)-2-hydroxypropanoate) 7-propanoate; MAC321; MAC-321. Grades: 98%. CAS No. 393101-41-2. Molecular formula: C44H55NO16. Mole weight: 853.90. BOC Sciences 8
Milciclib Cas No. 802539-81-7. BOC Sciences 8
Milnacipran Dimer Impurity B Milnacipran Dimer Impurity B is an impurity of Milnacipran, which is a serotonin-norepinephrine reuptake inhibitor (SNRI) used in the clinical treatment of fibromyalgia. Molecular formula: C25H31N3O4. Mole weight: 437.53. BOC Sciences 8
Minoxidil Sulfate Minoxidil sulfate is the active metabolite of Minoxidil and it is a potent vascular smooth muscle relaxant. Minoxidil sulfate is a selective ATP-sensitive potassium channel opener. Synonyms: 6-(1-Piperidinyl)-2,4-pyrimidinediamine-3-oxide Sulfate; 1,6-Dihydro-6-imino-4-(1-piperidinyl)-1-(sulfooxy)-2-pyrimidinamine. Grades: > 95%. CAS No. 83701-22-8. Molecular formula: C9H15N5O4S. Mole weight: 289.31. BOC Sciences 8
Mirabegron Mirabegron (formerly YM-178, trade name Myrbetriq) is a drug for the treatment of overactive bladder. It was developed by Astellas Pharma and was approved in the United States in July 2012. Mirabegron activates the β3 adrenergic receptor in the detrusor muscle in the bladder, which leads to muscle relaxation and an increase in bladder capacity. Uses: Adrenergic beta-3 receptor agonists. Synonyms: YM-178; YM 178; YM178. Grades: 0.99. CAS No. 223673-61-8. Molecular formula: C21H24N4O2S. Mole weight: 396.51. BOC Sciences 8
Mirabegron impurity 002 An impurity of Mirabegron. Mirabegron (formerly YM-178, trade name Myrbetriq) is a drug for the treatment of overactive bladder. It was developed by Astellas Pharma and was approved in the United States in July 2012. Mirabegron activates the β3 adrenergic receptor in the detrusor muscle in the bladder, which leads to muscle relaxation and an increase in bladder capacity. Synonyms: 4-ethoxy-3-methoxybenzonitrile; 81259-56-5; SCHEMBL6944897; MFCD02256107; AKOS000198357; 4-ETHOXY-3-METHOXY-BENZONITRILE; CS-0319395; Z54794538. Grades: 95%. CAS No. 81259-56-5. Molecular formula: C10H11NO2. Mole weight: 177.20. BOC Sciences 8
Mirabegron impurity 003 An impurity of Mirabegron. Mirabegron (formerly YM-178, trade name Myrbetriq) is a drug for the treatment of overactive bladder. It was developed by Astellas Pharma and was approved in the United States in July 2012. Mirabegron activates the β3 adrenergic receptor in the detrusor muscle in the bladder, which leads to muscle relaxation and an increase in bladder capacity. Synonyms: 4-fluoro-N-methyl-2-nitrobenzamide; SCHEMBL1668405; YLTRKOOKMIYJDB-UHFFFAOYSA-N; 1018983-85-1. Grades: 95%. CAS No. 1018983-85-1. Molecular formula: C8H7FN2O3. Mole weight: 198.15. BOC Sciences 8
Mirabegron Impurity 1 ((S)-Mirabegron) (S)-Mirabegron is an impurity of Mirabegron. Mirabegron is a potent bladder relaxant and reagent for diabetes remedy. Synonyms: (S) -2- (2-Aminothiazol-4-yl) -N- (4- (2- ( (2-hydroxy-2-phenylethyl) amino) ethyl) phenyl) acetamide. Grades: > 95%. CAS No. 1796931-48-0. Molecular formula: C21H24N4O2S. Mole weight: 396.51. BOC Sciences 8
Mirabegron Impurity 8 2HCl meta-Mirabegron is an isomer of Mirabegron, a potent bladder relaxant and reagent for diabetes remedy. Synonyms: meta-Mirabegron dihydrochloride; 2-Amino-N-[3-[2-[[(2R)-2-hydroxy-2-phenylethyl]amino]ethyl]phenyl]-4-thiazoleacetamide dihydrochloride. Grades: > 95%. Molecular formula: C21H24N4O2S.2HCl. Mole weight: 469.43. BOC Sciences 8
Mirodenafil Dihydrochloride Mirodenafil dihydrochloride is a newly developed oral phosphodiesterase type 5 (PDE-5) inhibitor developed for the treatment of erectile dysfunction. Synonyms: 5-Ethyl-3,5-dihydro-2-[5-[[4-(2-hydroxyethyl)-1-piperazinyl]sulfonyl]-2-propoxyphenyl]-7-propyl-4H-pyrrolo[3,2-d]pyrimidin-4-one Hydrochloride; 4-[[3-(5-Ethyl-4,5-dihydro-4-oxo-7-propyl-1H-pyrrolo[3,2-d]pyrimidin-2-yl)-4-propoxyphenyl]sulfonyl]-1-piperazineethanol Dihydrochloride; Mirodenafil 2HCl; M-vix; SK 3530 dihydrochloride; SK3530 dihydrochloride; SK-3530 dihydrochloride. Grades: > 98%. CAS No. 862189-96-6. Molecular formula: C26H39Cl2N5O5S. Mole weight: 604.59. BOC Sciences 8
Mirogabalin This active molecular is an α2δ-1 ligand being developed for pain associated with diabetic peripheral neuropathy, fibromyalgia, and postherpetic neuralgia which related to related to drugs such as gabapentin and pregabalin. Mirogabalin binds to the α2δ calcium channels (1 and 2) and was estimated to be much more potent than pregabalin. In Nov 2015, a Japanese company named Daiichi Sankyo plans a phase III trial for Postherpetic neuralgia and Neuropathic pain (in patients with diabetic peripheral neuropathy and renal impairment) in Japan. In May 2016, Pharmacokinetics and adverse data from a phase I trial in volunteers presented at the 35th Annual Scientific Meeting of the American Pain Society. Uses: Treatment of diabetic peripheral neuropathic pain. Synonyms: 2-[(1R,5S,6S)-6-(aminomethyl)-3-ethyl-6-bicyclo[3.2.0]hept-3-enyl]acetic acid, DS-5565,CAS#1138245-21-2 ( Mirogabalin besylate). Grades: 98%. CAS No. 1138245-13-2. Molecular formula: C12H19NO2. Mole weight: 209.29. BOC Sciences 8
Mitiglinide calcium hydrate Mitiglinide calcium hydrate, a derivative of benzylsuccinic acid, is a highly selective KATP channel antagonist. Uses: Hypoglycemic agents. Synonyms: calcium;(2S)-4-[(3aS,7aR)-1,3,3a,4,5,6,7,7a-octahydroisoindol-2-yl]-2-benzyl-4-oxobutanoate;dihydrate 207844-01-7 C38H48CaN2O6.2H2O Mitiglinidecalcium Calcium Mitiglinide 2150AH. Grades: >99.0%. CAS No. 207844-01-7. Molecular formula: C38H52CaN2O8. Mole weight: 704.91. BOC Sciences 8
Mitoxantrone Mitoxantrone is a type II topoisomerase inhibitor with IC50 of 2.0 μM, 0.42 mM for HepG2 and MCF-7/wt cells, respectively. It is used in the treatment of certain types of cancer, mostly metastatic breast cancer, acute myeloid leukemia, and non-Hodgkin's lymphoma. Uses: Analgesics. Synonyms: mitoxantrone; 65271-80-9; Mitoxanthrone; Mitozantrone; DHAQ. Grades: >98%. CAS No. 65271-80-9. Molecular formula: C22H28N4O6. Mole weight: 444.48. BOC Sciences 8
Mivebresib Mivebresib is a BET inhibitor with potential antineoplastic activity. It disrupts critical transcription programs that drive prostate cancer growth to induce potent anti-tumor activity in vitro and in vivo. Mivebresib is also a MYC and the TMPRSS2-ETS fusion proteins inhibitor. Mivebresib can inhibit cell growth in susceptible tumors. Uses: Anti-tumor. Synonyms: ABBV-075; ABBV 075; ABBV075; Mivebresib;N-(4-(2,4-difluorophenoxy)-3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)phenyl)ethanesulfonamide. Grades: 98%. CAS No. 1445993-26-9. Molecular formula: C22H19F2N3O4S. Mole weight: 459.47. BOC Sciences 8
Mizagliflozin Mizagliflozin is a sodium-glucose transporter inhibitor. It is expected to improve postprandial hyperglycemia by suppressing glucose absorption from the intestine. It blocks intestinal glucose absorption and reduces GIP secretion in rats and humans, which suggests SGLT1 glucose transport is critical for GIP release. It is used for the treatment of diabetes. Synonyms: DSP-3235, DSP3235; DSP 3235; KGA-3235; KGA 3235; KGA3235; GSK-1614235; GSK 1614235; GSK1614235. Grades: 98%. CAS No. 666843-10-3. Molecular formula: C28H44N4O8. Mole weight: 564.68. BOC Sciences 8
MK-0731 MK-0731 is a synthetic small molecule with potential antineoplastic activity. MK0731 selectively inhibits kinesin spindle protein (KSP), which may result in the inhibition of mitotic spindle assembly, induction of cell cycle arrest during the mitotic phase, and apoptosis in tumor cells that overexpress KSP. Uses: Potential antineoplastic agent. Synonyms: ALR-3456; ALR 3456; ALR3456; 845256-65-7; MK0731, MK-0731, MK 0731; UNII-8HIJ5G3O02; 8HIJ5G3O02. CAS No. 845256-65-7. Molecular formula: C25H28F3N3O2. Mole weight: 459.513. BOC Sciences 8
MK-1775 MK-1775, also known as AZD-1775, is a WEE1 inhibitor and a small-molecule inhibitor of the tyrosine kinase WEE1 with potential antineoplastic sensitizing activity. MK-1775 selectively targets and inhibits WEE1, a tyrosine kinase that phosphorylates cyclin-dependent kinase 1 (CDC2) to inactivate the CDC2/cyclin B complex. Inhibition of WEE1 activity prevents the phosphorylation of CDC2 and impairs the G2 DNA damage checkpoint. This may lead to apoptosis upon treatment with DNA damaging chemotherapeutic agents. Unlike normal cells, most p53-deficient or mutated human cancers lack the G1 checkpoint as p53 is the key regulator of the G1 checkpoint and these cells rely on the G2 checkpoint for DNA repair to damaged cells. Annulment of the G2 checkpoint may therefore make p53-deficient tumor cells more vulnerable to antineoplastic agents and enhance their cytotoxic effect. Synonyms: MK-1775; MK1775; MK 1775; AZD1775; AZD-1775; AZD 1775; adavosertib. 1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-6-[4-(4-methylpiperazin-1-yl)anilino]-2-prop-2-enylpyrazolo[3,4-d]pyrimidin-3-one. Grades: >98%. CAS No. 955365-80-7. Molecular formula: C27H32N8O2. Mole weight: 500.607. BOC Sciences 8
MK-2206 dihydrochloride MK-2206 is a highly selective Akt inhibitor with IC50 of 8 nM, 12 nM and 65 nM for Akt1, Akt2 and Akt3, respectively. It is undergoing a phase II clinical trial for the treatment of ovarian, fallopian tube, or primary peritoneal cancer where there are mutations in P13K or AKT or low levels of PTEN. Synonyms: MK-2206. MK 2206. MK2206. Grades: >98%. CAS No. 1032350-13-2. Molecular formula: C25H23Cl2N5O. Mole weight: 480.4. BOC Sciences 8
MK-5172 Grazoprevir is a hepatitis C virus protease inhibitor developed for the treatment of hepatitis C. It suppresses NS3 and NS4A, which play a role in the virus splitting its polyprotein into the functional virus proteins. Grazoprevir is often used in combination with elbasvir or ribavirin. Uses: Antiviral agents. Synonyms: Cyclopropanecarboxamide, N-[[[ (1R, 2R) -2-[5- (3-hydroxy-6-methoxy-2-quinoxalinyl) pentyl]cyclopropyl]oxy]carbonyl]-3-methyl-L-valyl- (4R) -4-hydroxy-L-prolyl-1-amino-N- (cyclopropylsulfonyl) -2-ethenyl-, cyclic (1?2)-ether, (1R,2S)-; Grazoprevir; (1R, 2S) -N-[[[ (1R, 2R) -2-[5- (3-Hydroxy-6-methoxy-2-quinoxalinyl) pentyl]cyclopropyl]oxy]carbonyl]-3-methyl-L-valyl- (4R) -4-hydroxy-L-prolyl-1-amino-N- (cyclopropylsulfonyl) -2-ethenylcyclopropanecarboxamide Cyclic (1?2)-Ether. Grades: >98%. CAS No. 1350514-68-9. Molecular formula: C38H50N6O9S. Mole weight: 766.91. BOC Sciences 8
MK-8722 MK-8722 is a potent pan-AMPK activator that improves glucose homeostasis but induces cardiac hypertrophy. AMPK has long been of interest as a target for the treatment of Type 2 Diabetes Mellitus. Synonyms: MK 8722; MK8722. CAS No. 1394371-71-1. Molecular formula: C24H20ClN3O4. Mole weight: 449.9. BOC Sciences 8
MKC-3946 MKC-3946 is a potent inhibitor of inositol-requiring enzyme 1α (IRE1α). It inhibits XBP1 mRNA splicing and exhibits cytotoxicity against AML cells. MKC-3946 leads to modest growth inhibition in MM cells but has no effect on normal mononuclear cells in vitro. Synonyms: MKC-3946; MKC 3946; MKC3946; 2-hydroxy-6-(5-(4-methylpiperazine-1-carbonyl)thiophen-2-yl)-1-naphthaldehyde. Grades: >98%. CAS No. 1093119-54-0. Molecular formula: C21H20N2O3S. Mole weight: 380.462. BOC Sciences 8
ML204 ML204 is a novel and potential TRPC4 Channel inhibitor. ML204 inhibited TRPC4β-mediated intracellular Ca(2+) rise with an IC(50) value of 0.96 μm and exhibited 19-fold selectivity against muscarinic receptor-coupled TRPC6 channel activation. Synonyms: 4-Methyl-2-piperidin-1-ylquinoline; ML204; ML 204; ML-204. Grades: > 98%. CAS No. 5465-86-1. Molecular formula: C15H18N2. Mole weight: 226.323. BOC Sciences 8
ML 297 ML 297 is a Kir3.1/3.2 (GIRK1/2) channel activator with IC50 values of 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3. Synonyms: ML297; ML 297; ML-297; N-(3,4-Difluorophenyl)-N'-(3-methyl-1-phenyl-1H-pyrazol-5-yl)urea. Grades: ≥99% by HPLC. CAS No. 1443246-62-5. Molecular formula: C17H14F2N4O. Mole weight: 328.32. BOC Sciences 8
ML324 ML324 exhibits good Caco-2 cell permeability, and possesses excellent microsomal stability in the presence of both mouse and rat liver microsomes. Synonyms: ML-324; ML 324; ML324; CID-44143209; CID 44143209; CID44143209. Grades: >98%. CAS No. 1222800-79-4. Molecular formula: C21H23N3O2. Mole weight: 349.43. BOC Sciences 8
ML 67-33 ML 67-33 is a K2P potassium channel activator that increases channel currents by activating core gating apparatus of channels. Synonyms: 2,7-Dichloro-9,10-dihydro-9,9-dimethyl-10-[2-(2H-tetrazol-5-yl)ethyl]acridine. Grades: 97%. CAS No. 1443290-89-8. Molecular formula: C18H17Cl2N5. Mole weight: 374.27. BOC Sciences 8
MLN0128 MLN0128, also known as INK128, is a TORC1/2 inhibitor, is also an orally bioavailable inhibitor of raptor-mTOR (TOR complex 1 or TORC1) and rictor-mTOR (TOR complex 2 or TORC2) with potential antineoplastic activity. TORC1/2 inhibitor INK128 binds to and inhibits both TORC1 and TORC2 complexes of mTOR, which may result in tumor cell apoptosis and a decrease in tumor cell proliferation. TORC1 and 2 are upregulated in some tumors and play an important role in the PI3K/Akt/mTOR signaling pathway, which is frequently dysregulated in human cancers. Synonyms: TAK-228; TAK 228; TAK228; INK128; INK-128; INK 128; MLN0128; MLN 0128; MLN-0128; Sapanisertib. Grades: >98%. CAS No. 1224844-38-5. Molecular formula: C15H15N7O. Mole weight: 309.333. BOC Sciences 8
ML SA1 ML SA1 is an activator of TRPML channels. It can induce TRPML-mediated Ca2+ release from lysosomes and reduce cholesterol accumulation in Niemann-Pick type C macrophages. Synonyms: 2-[2-(3,4-Dihydro-2,2,4-trimethyl-1(2H)-quinolinyl)-2-oxoethyl]-1H-isoindole-1,3(2H)-dione. Grades: ≥99% by HPLC. CAS No. 332382-54-4. Molecular formula: C22H22N2O3. Mole weight: 362.42. BOC Sciences 8
ML-SI3 ML-SI3 is an antagonist of the TRPML family of calcium channels. ML-SI3 can prevent lysosomal calcium efflux and has been reported to block downstream TRPML1-mediated induction of autophagy. Synonyms: N- [2- [4- (2-methoxyphenyl) -1-piperazinyl] cyclohexyl] benzenesulfonamide. CAS No. 891016-02-7. Molecular formula: C23H31N3O3S. Mole weight: 429.58. BOC Sciences 8
MM-419447 (Linaclotide Metabolite) Trifluoroacetic acid MM-419447 (Linaclotide Metabolite) Trifluoroacetic acid is a metabolite of Linaclotide, which is a peptide agonist of guanylate cyclase 2C used to treat abdominal pain associated with constipation in patients with irritable bowel syndrome (IBS). Synonyms: L-cysteinyl-L-cysteinyl-L-α-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparaginyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteine trifluoroacetic acid; L-Cysteine, L-cysteinyl-L-cysteinyl-L-α-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparaginyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonylglycyl-, trifluoroacetic acid (1:x); H-Cys-Cys-Glu-Tyr-Cys-Cys-Asn-Pro-Ala-Cys-Thr-Gly-Cys-OH.TFA. Grades: 97%. Molecular formula: C50H76N14O19S6.xC2HF3O2. Mole weight: 1369.61 (free base). BOC Sciences 8
m-Methyl Atomoxetine Hydrochloride M-Methyl Atomoxetine Hydrochloride is an impurity of Atomoxetine, which is a selective norepinephrine (NE) reuptake inhibitor for the treatment of attention-deficit hyperactivity disorder (ADHD). Synonyms: N-Methyl-γ-(3-methylphenoxy)benzenepropanamine Hydrochloride; Atomoxetine Related Compound B Hydrochloride; rac-Atomoxetine EP Impurity D HCl; Atomoxetine USP Related Compound B; N-methyl-3-phenyl-3-(m-tolyloxy)propan-1-amine hydrochloride (1:1). Grades: ≥90%. CAS No. 873310-28-2. Molecular formula: C17H22ClNO. Mole weight: 291.81. BOC Sciences 8
Moclobemide Moclobemide is a reversible monoamine oxidase A (MAO-A) inhibitor, displaying antidepressive activity. Synonyms: Ro11-1163; Ro 11-1163; Ro111163; Ro-111163; Ro 111163; Moclobemide; brand name: Amira; Aurorix; Clobemix; Depnil; Manerix; 4-chloro-N-(2-morpholin-4-ylethyl)benzamide. Grades: 98%. CAS No. 71320-77-9. Molecular formula: C13H17ClN2O2. Mole weight: 268.74. BOC Sciences 8
Mofezolac Mofezolac is a cyclooxygenase-1 selective inhibitor. Uses: Cyclooxygenase inhibitors. Synonyms: Disopain; N-22; N 22; N22. CAS No. 78967-07-4. Molecular formula: C19H17NO5. Mole weight: 339.345. BOC Sciences 8
MOG (35-55) (MOG) 35-55 is a minor component of CNS myelin. Produces a relapsing-remitting neurological disease with extensive plaque-like demyelination. Synonyms: MOG35-55. Grades: >98%. CAS No. 149635-73-4. Molecular formula: C118H177N35O29S. Mole weight: 2581.95. BOC Sciences 8
Mometasone Furoate Mometasone furoate, prodrug of the free form mometasone, is an agent with high affinity for the glucocorticoid receptor with anti-allergic property. It can be used to treat asthma and allergic rhinitis. Uses: The treatment of asthma and allergic rhinitis. Synonyms: Elocon; Nasonex; Sch32088; Twisthaler; Elomet; Asmanex; Mometasone 17-furoate. Grades: 98%. CAS No. 83919-23-7. Molecular formula: C27H30Cl2O6. Mole weight: 521.43. BOC Sciences 8
Mometasone Furoate Impurity M Cas No. 57780-86-6. BOC Sciences 8
Mometasone Furoate Impurity R Cas No. 1370190-08-1. BOC Sciences 8
Mometasone Furoate Impurity S Cas No. 2231764-75-1. BOC Sciences 8
Monic Acid A Monic Acid A is a metabolite of Mupirocin, which is a carboxylic acid bacteriostatic/bactericidal antibiotic. Synonyms: (2E)-5,9-Anhydro-2,3,4,8-tetradeoxy-8-[[(2S,3S)-3-[(1S,2S)-2-hydroxy-1-methylpropyl]oxiranyl]methyl]-3-methyl-L-talo-non-2-enonic Acid; [2E,8[2S,3S(1S,2S)]]-5,9-anhydro-2,3,4,8-tetradeoxy-8-[[3-(2-hydroxy-1-methylpropyl)oxiranyl]methyl]-3-methyl-L-talo-non-2-enonic Acid; Monic Acid. Grades: 95%. CAS No. 66262-68-8. Molecular formula: C17H28O7. Mole weight: 344.40. BOC Sciences 8
Monic Acid A Methyl Ester-Tri(tert-butyldimethylsilyl) Ether Monic Acid A Methyl Ester-Tri(tert-butyldimethylsilyl) Ether is an intermediate in the synthesis of Monic Acid A, which is the major metabolite of the antibiotic Mupirocin. Synonyms: Methyl (2E)-4-[(2S,3S,4R,5S)-3,4-bis{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-5-({(2S,3S)-3-[(2R,3S)-3-{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-butanyl]-2-oxiranyl}methyl)tetrahydro-2H-pyran-2-yl]-3-methyl-2-butenoate. Molecular formula: C36H72O7Si3. Mole weight: 701.21. BOC Sciences 8
Monodecarboxy Ticarcilloic Acid Monodecarboxy Ticarcilloic Acid is an impurity of Ticarcillin, which is a β-lactam carboxylpenicillin antibiotic used to treat Gram-negative bacteria, particularly Pseudomonas aeruginosa and Proteus vulgaris. Synonyms: (4S)-2-({[(2R)-2-Carboxy-2-(3-thienyl)acetyl]amino}methyl)-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid; 4-Thiazolidinecarboxylic acid, 2-[[[(2R)-2-carboxy-2-(3-thienyl)acetyl]amino]methyl]-5,5-dimethyl-, (4S)-. Grades: 98%. CAS No. 57414-13-8. Molecular formula: C14H18N2O5S2. Mole weight: 358.43. BOC Sciences 8
mono-Ethyl fumarate Monoethyl Fumarate is an anti-psoriatic fumaric acid ester. It was used in the preparation of photo-crosslinkable macromers. It was also used to synthesize Ugi/intramolecular Diels-Alder (IMDA) cycloaddition products. Uses: Fumaric acid monoethyl ester (quetiapine ep impurity r) is an anti-psoriatic fumaric acid ester. fumaric acid monoethyl ester inhibited thymidine-14c incorporation into dna by cultured human lymphocytes. fumaric acid monoethyl ester has been shown to evoke transient increase in intracellular free calcium concentration and inhibit proliferation of human keratinocytes. Synonyms: (E)-4-ethoxy-4-oxobut-2-enoic acid. Grades: > 95 %. CAS No. 2459-5-4. Molecular formula: C6H8O4. Mole weight: 144.13. BOC Sciences 8
Monohydroxy Etravirine A derivative of Etravirine. Etravirine is a non-nucleoside reverse transcriptase inhibitor. Synonyms: Monohydroxy Etravirine. Grades: > 95%. CAS No. 1246815-68-8. Molecular formula: C20H15BrN6O2. Mole weight: 451.29. BOC Sciences 8
Mono-Hydroxy Sugammadex Mono-Hydroxy Sugammadex is an impurity of sugammadex, a cyclodextrin agent indicated for the treatment of neuromuscular blockade induced by rocuronium and vecuronium. It inactivates rocuronium by encapsulating (chelating) the free molecule to form a stable complex. Synonyms: Sugammadex Monohydroxy Impurity. CAS No. 2376607-99-5. Molecular formula: C69H101O47S7.7Na. Mole weight: 2067.87. BOC Sciences 8
Mono-Methylated Fidaxomicin A derivative of Fidaxomycin. Fidaxomycin is a natural macrocyclic antibiotic that inhibits RNA polymerase with selectivity for Gram-positive bacteria over Gram-negative bacteria. Synonyms: Methylated Clostomicin B1. Grades: > 95%. Molecular formula: C53H76Cl2O18. Mole weight: 1072.09. BOC Sciences 8
Monomethyl Benzylpenicilloate Synonyms: (2R,4S)-2-[(1R)-2-methoxy-2-oxo-1-[(2-phenylacetyl)amino]ethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid; (3S,5R,6R)-methylbenzylpenicilloate; Methyl (3S,5R,6R)-benzylpenicilloate; (3S,5R,6R)-Monomethyl benzylpenicilloate; Methyl benzylpenicilloate; 2-Thiazolidineacetic acid, 4-carboxy-5,5-dimethyl-α-[(phenylacetyl)amino]-, α-methyl ester, [2R-[2α(R*),4β]]-. Grades: ≥95%. CAS No. 59054-27-2. Molecular formula: C17H22N2O5S. Mole weight: 366.43. BOC Sciences 8
Montelukast Acyl-β-D-glucuronide Acetic Acid Salt Montelukast Acyl-β-D-glucuronide Acetic Acid Salt is a metabolite of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Synonyms: 1-O- ({1-[ ({ (1R) -1-{3-[ (E) -2- (7-Chloro-2-quinolinyl) vinyl]phenyl}-3-[2- (2-hydroxy-2-propanyl) phenyl]propyl}sulfanyl) methyl]cyclopropyl}acetyl) -α -D-erythro-hexopyranuronic acid acetate (1:1); α-D-erythro-Hexopyranuronic acid, 1- [2- [1- [ [ [ (1R) -1- [3- [ (E) -2- (7-chloro-2-quinolinyl) ethenyl] phenyl] -3- [2- (1-hydroxy-1-methylethyl) phenyl] propyl] thio] methyl] cyclopropyl] acetate] , acetate (1:1) (salt); 1- [1- [ [ [ (1R) -1- [3- [ (1E) -2- (7-Chloro-2-quinolinyl) ethenyl] phenyl] -3- [2- (1-hydroxy-1-methylethyl) phenyl] propyl] thio] methyl] cyclopropaneacetate] β-D-Glucopyranuronic Acid Acetic Acid Salt; Montelukast M1 Acetic acid Salt. Grades: ≥95%. Molecular formula: C43H48ClNO11S. Mole weight: 822.36. BOC Sciences 8
Montelukast Cyclized Ether impurity Montelukast Cyclized Ether impurity is an impurity of Montelukast, which is a leukotriene receptor antagonist indicated for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. Synonyms: Montelukast Impurity 39; 2-(3-(1,1-dimethyl-1,3,4,5-tetrahydrobenzo[c]oxepin-3-yl)styryl)-7-chloroquinoline; Quinoline, 7-chloro-2-[2-[3-(1,3,4,5-tetrahydro-1,1-dimethyl-2-benzoxepin-3-yl)phenyl]ethenyl]-; 7-Chloro-2-[2-[3-(1,3,4,5-tetrahydro-1,1-dimethyl-2-benzoxepin-3-yl)phenyl]ethenyl]quinoline. Grades: ≥95%. CAS No. 168214-67-3. Molecular formula: C29H26ClNO. Mole weight: 439.97. BOC Sciences 8
Montelukast Dicarboxylic Acid (Mixture of Diastereomers) Montelukast Dicarboxylic Acid (Mixture of Diastereomers) is a metabolite of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Synonyms: 2-[ (3R) -3-[[[1- (Carboxymethyl) cyclopropyl]methyl]thio]-3-[3-[ (1E) -2- (7-chloro-2-quinolinyl) ethenyl]phenyl]propyl]-α -hydroxy-α -methylbenzeneacetic Acid; Benzeneacetic acid, 2-[ (3R) -3-[[[1- (carboxymethyl) cyclopropyl]methyl]thio]-3-[3-[ (E) -2- (7-chloro-2-quinolinyl) ethenyl]phenyl]propyl]-α -hydroxy-α -methyl-. Grades: ≥90%. CAS No. 213380-27-9. Molecular formula: C35H34ClNO5S. Mole weight: 616.17. BOC Sciences 8
Montelukast Dicyclohexylamine Salt Montelukast is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Uses: A selective leukotriene d4-receptor antagonist. used as an antiasthmatic. Synonyms: 1- [1- [ [ [ (1R) -1- [3- [ (1E) -2- (7-Chloro-2-quinolinyl) ethenyl] phenyl] -3- [2- (1-hydroxy-1-methylethyl) phenyl] propyl] thio] methyl] cyclopropaneacetic N-Cyclohexylcyclohexanamine; Montelukast DCHA. Grades: 95%. CAS No. 577953-88-9. Molecular formula: C47H59ClN2O3S. Mole weight: 767.50. BOC Sciences 8
Montelukast Gem-dimethylmethylene Analogue Montelukast Gem-dimethylmethylene Analogue is an analog of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Uses: An analog of montelukast, used for preparation of mk-0476. Synonyms: [R- (E) ]-3-[[[1-[3-[2- (7-Chloro-2-quinolinyl) ethenyl]phenyl]-3-[2- (1-hydroxy-1-methylethyl) phenyl]propyl]thio]methyl]-3-methylbutanoic Acid; 4-({(1R)-1-{3-[(E)-2-(7-Chloro-2-quinolinyl)vinyl]phenyl}-3-[2-(2-hydroxy-2-propanyl)phenyl]propyl}sulfanyl)-3,3-dimethylbutanoic acid; Butanoic acid, 4-[[(1R)-1-[3-[(E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]-3,3-dimethyl-; 4-{(R)-1-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-phenyl}-3-[2-(1-hydroxy-1-methyl-ethyl)-phenyl]-propylsulfanyl}-3,3-dimethyl-butyric acid. Grades: ≥95%. CAS No. 162489-70-5. Molecular formula: C35H38ClNO3S. Mole weight: 588.20. BOC Sciences 8
Montelukast Related Impurity 1 An impurity of Montelukast Sodium, which is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. Synonyms: 1-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]-1-propanone. Grades: > 95%. CAS No. 1258428-71-5. Molecular formula: C29H26ClNO2. Mole weight: 455.99. BOC Sciences 8
Montelukast Related Impurity 2 An impurity of Montelukast Sodium, which is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. Synonyms: 2-[3-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-oxopropyl]benzoic Acid Methyl Ester; Methyl (E)-2-[3-[3-[2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-oxopropyl]benzoate. Grades: > 95%. CAS No. 149968-11-6. Molecular formula: C28H22ClNO3. Mole weight: 455.95. BOC Sciences 8
Montelukast S-Enantiomer Sodium Salt An impurity of Montelukast Sodium, which is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. Synonyms: 1- [ [ [ (1S) -1- [3- [ (1E) -2- (7-Chloro-2-quinolinyl) ethenyl] phenyl] -3- [2- (1-hydroxy-1-methylethyl) phenyl] propyl] thio] methyl] cyclopropaneacetic Acid Sodium Salt; L 768232; Montelukast EP Impurity A. Grades: > 95%. CAS No. 190078-45-6. Molecular formula: C35H35ClNO3S.Na. Mole weight: 608.2. BOC Sciences 8
Montelukast Sulfoxide Sodium An impurity of Montelukast Sodium, which is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. Synonyms: Cyclopropaneacetic acid, 1-[[[1-[3-[2- (7-chloro-2-quinolinyl) ethenyl]phenyl]-3-[2- (1-hydroxy-1-methylethyl) phenyl]propyl]sulfinyl]methyl]-, sodium salt (1:1); Cyclopropaneacetic acid, 1-[[[1-[3-[2- (7-chloro-2-quinolinyl) ethenyl]phenyl]-3-[2- (1-hydroxy-1-methylethyl) phenyl]propyl]sulfinyl]methyl]-, monosodium salt. Grades: >95%. CAS No. 909796-71-0. Molecular formula: C35H35ClNNaO4S. Mole weight: 624.19. BOC Sciences 8
Mosapride Citrate Dihydrate Mosapride Citrate Dihydrate is a citrate hydrate form of Mosapride, which is a 5-HT4 receptor agonist and 5-HT3 receptor antagonist. It is used as a gastroprokinetic agent. Synonyms: Mosapride citrate salt dihydrate; 4-Amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl ]-2-morpholinyl]methyl]benzamide citrate dihydrate; Gasmotin. Grades: >95%. CAS No. 636582-62-2. Molecular formula: C21H25ClFN3O3·C6H8O7·2H2O. Mole weight: 650.05. BOC Sciences 8
Mosapride Citric Amide Disodium Salt Mosapride Citric Amide Disodium Salt is a derivative of Mosapride, which is a 5-HT4 receptor agonist and 5-HT3 receptor antagonist. It is used as a gastroprokinetic agent. Synonyms: Mosapride impurity 10; sodium 3- ( (2-chloro-5-ethoxy-4- ( ( (4- (4-fluorobenzyl) morpholin-2-yl) methyl) carbamoyl) phenyl) carbamoyl) -3-hydroxypentanedioate; 3- [ [ [2-Chloro-5-ethoxy-4- [ [ [ [4- [ (4-fluorophenyl) methyl] -2-morpholinyl] methyl] amino] carbonyl] phenyl] amino] carbonyl] -3-hydroxypentanedioic Acid Disodium Salt. Grades: 94%. Molecular formula: C27H29ClFN3Na2O9. Mole weight: 639.96. BOC Sciences 8
Motesanib Motesanib is a multikinase inhibitor that selectively targets VEGF receptors, platelet-derived growth factor receptors (PDGFRs), and Kit receptors. It also potently inhibits angiogenesis and induces regression in tumor xenografts. Uses: Protein kinase inhibitors. Synonyms: N-(3,3-dimethyl-2,3-dihydro-1H-indol-6-yl)-2-[(pyridin-4- ylmethyl)amino]pyridine-3-carboxamide; AMG 706; AMG706; AMG706; motesanib. Grades: >98%. CAS No. 453562-69-1. Molecular formula: C22H23N5O. Mole weight: 373.45. BOC Sciences 8
Motesanib Diphosphate Motesanib Diphosphate is a potent ATP-competitive inhibitor of VEGFR1/2/3 with IC50 of 2 nM/3 nM/6 nM, respectively; similar activity against Kit, ~10-fold more selective for VEGFR than PDGFR and Ret. Uses: Protein kinase inhibitors. Synonyms: Motesanib diphosphate; 857876-30-3; AMG-706; Motesanib (Diphosphate); Motesanib Diphosphate (AMG-706); Motesanib diphosphate [USAN]; Motesanib phosphate; AMG 706 (Diphosphate); AMG 706; ; T6Q3060U91; Motesanib phosphate (JAN); Motesanib diphosphate (USAN); N-(3,3-dimethyl-1,2-dihydroindol-6-yl)-2-(pyridin-4-ylmethylamino)pyridine-3-carboxamide; phosphoric acid; MOTESANIB PHOSPHATE [JAN]; 3-Pyridinecarboxamide, N-(2,3-dihydro-3,3-dimethyl-1H-indol-6-yl)-2-((4-pyridinylmethyl)amino)-, phosphate (1:2). Grades: >98%. CAS No. 857876-30-3. Molecular formula: C22H29N5O9P2. Mole weight: 569.44. BOC Sciences 8
Motolimod Motolimod is a small-molecule agonist of TLR8, with potential immunostimulating and antineoplastic activities. Synonyms: VTX-2337; VTX 2337; VTX2337; Motolimod; 2-amino-N,N-dipropyl-8-(4-(pyrrolidine-1-carbonyl)phenyl)-3H-benzo[b]azepine-4-carboxamide. CAS No. 926927-61-9. Molecular formula: C28H34N4O2. Mole weight: 458.6. BOC Sciences 8
MOTS-C MOTS-C is a peptide hormone encoded in the mitochondrial genome. It regulates metabolic homeostasis and enhances physical performance. Synonyms: H-Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg-OH. Grades: 98%. CAS No. 1627580-64-6. Molecular formula: C101H152N28O22S2. Mole weight: 2174.6. BOC Sciences 8
Moxifloxacin Impurity O An impurity of Moxifloxacin, a fourth-generation antibacterial drug. Synonyms: ethyl 1-cyclopropyl-7-fluoro-6,8-dimethoxy-4-oxo-1,4-dihydroquinoline-3-carboxylate; 3-Quinolinecarboxylic acid, 1-cyclopropyl-7-fluoro-1,4-dihydro-6,8-dimethoxy-4-oxo-, ethyl ester. Grades: 98%. CAS No. 2489671-14-7. Molecular formula: C17H18FNO5. Mole weight: 335.33. BOC Sciences 8
Moxifloxacin impurity Q An impurity of Moxifloxacin, a fourth-generation antibacterial drug. Synonyms: ethyl 1-cyclopropyl-7,8-difluoro-6-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylate; 1-Cyclopropyl-7-8-difluoro-6-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid Ethyl Ester. CAS No. 1329836-33-0. Molecular formula: C16H15F2NO4. Mole weight: 323.29. BOC Sciences 8

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