BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Guanosine 3'-(trihydrogen diphosphate), 5'-(trihydrogen diphosphate) | Guanosine 3'-(trihydrogen diphosphate), 5'-(trihydrogen diphosphate) is an imperative molecule aiding in the study against cancer, viral infections and neurological disorders. Synonyms: ppGpp; Guanosine 3',5'-bisdiphosphate. Grade: 95%. CAS No. 32452-17-8. Molecular formula: C10H17N5O17P4. Mole weight: 603.16. |  |
| Guanosine, 4'-?C-?ethenyl- | 4'-C-ethenyl-guanosine is an indispensable biomolecule employed in the realm of biomedical investigation. It primarily finds application in the fabrication and research of antiviral compounds, especially for studying maladies instigated by RNA viruses. As a precursor to nucleic acids, this compound plays a pivotal role in restraining viral duplication and studying perilous contagions. CAS No. 1892590-33-8. Molecular formula: C12H15N5O5. Mole weight: 309.28. | |
| Guanosine-5'-[(beta,gamma)-imido]triphosphate sodium salt | Guanosine-5'-[(beta,gamma)-imido]triphosphate sodium salt is a vital compound extensively used in biomedical field for its role as a potent activator of G protein-coupled receptors (GPCRs). It facilitates signal transduction pathways in various cellular processes, including neurotransmission, hormone regulation and immune responses. Synonyms: GMPPNP; GppNHp. Molecular formula: C10H17N6O13P3·xNa. Mole weight: 522.20 (free acid). | |
| Guanosine-5'-[(beta,gamma)-methyleno]triphosphate sodium salt | Guanosine 5'-[beta,gamma-methylene]triphosphate is a nucleoside triphosphate analogue that is guanosine substituted at position 5' by a (beta,gamma-methylene)triphosphate group. It is a conjugate acid of a guanosine 5'-[beta,gamma-methylene]triphosphate(4-). Synonyms: GMPPCP; GppCp. Molecular formula: C11H18N5O13P3·xNa. Mole weight: 521.21 (free acid). | |
| Guanosine-5'-carboxylic acid | Guanosine-5'-carboxylic acid, a pivotal component in the realm of biomedicine, holds immense importance. Its primary role revolves around the exploration and innovation of antiviral pharmaceuticals, with a specific focus on tackling herpes simplex and varicella-zoster viruses. By serving as a fundamental cornerstone for the synthesis of robust antiviral agents, this compound actively drives significant progress in the treatment landscape of viral ailments. Synonyms: 1-(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)-1-deoxy-b-D-ribofuranuronic acid; (2S,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydro-2-furancarboxylic acid; 5'-Guanylsaeure; 1-(2-amino-6-oxo-1,6-dihydro-purin-9-yl)-β-D-1-deoxy-ribofuranuronic acid. Grade: ≥95%. CAS No. 15596-14-2. Molecular formula: C10H11N5O6. Mole weight: 297.22. | |
| Guanosine 5'-diphosphate | Guanosine 5'-diphosphate (GDP) is a nucleotide composed of the base guanine, the sugar ribose, and two phosphate groups. It plays a crucial role in cellular processes, acting as a substrate in signal transduction pathways and as a building block in RNA synthesis. GDP is also involved in energy transfer and regulatory mechanisms within cells, particularly in GTP-binding proteins and metabolic pathways. Synonyms: GDP; ((2R,3S,4R,5R)-5-(2-Amino-6-oxo-1H-purin-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl trihydrogen diphosphate; Guanosine diphosphate; 2-amino-9-{5-O-[hydroxy(phosphonooxy)phosphoryl]-β-D-ribofuranosyl}-9H-purin-6-ol; Guanosine 5'-(trihydrogen diphosphate). Grade: ≥95% by HPLC. CAS No. 146-91-8. Molecular formula: C10H15N5O11P2. Mole weight: 443.20. | |
| Guanosine 5'-diphosphate disodium salt | Guanosine 5'-diphosphate disodium salt is an imperative biomolecule esteemed in the biomedical sector, exhibiting noteworthy involvement in cellular signaling and serves as a substrate for diverse nucleic acid metabolism-encompassing enzymes. Its significance is exemplified through extensive employment in research and manufacturing, enabling comprehensive exploration of G-protein coupled receptors, protein synthesis and drug discovery-related signaling pathways, as well as disease research. Synonyms: GDP-Na2; Disodium 5'-O-{[(hydroxyphosphinato)oxy]phosphinato}guanosine; GDP.Na2; 5'-GDP-Na2; Guanosine 5'-(trihydrogen diphosphate), disodium salt; Guanosinepyrophosphate, disodium salt; Disodium guanosine 5'-diphosphate; Guanosine-5'-diphosphoric acid disodium salt. Grade: 98%. CAS No. 7415-69-2. Molecular formula: C10H13N5Na2O11P2. Mole weight: 487.16. | |
| Guanosine 5'-diphosphate sodium salt | A pyruvate kinase substrate. Synonyms: Guanosine 5'-diphosphate sodium salt; 43139-22-6; MFCD00070121; DTXSID101036037; Guanosine-5'-diphosphate sodium salt; sodium ((2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogendiphosphate. Molecular formula: C10H15N5O11P2·xNa. Mole weight: 443.20 (free acid). | |
| Guanosine 5'-Diphosphate Triammonium Salt | Guanosine 5'-Diphosphate Triammonium Salt is an intermediate in the eukaryotic messenger ribonucleic acid cap binding protein synthesis. Synonyms: Guanosine 5'-(Trihydrogen Diphosphate), Triammonium Salt; Triammonium Guanosine 5'-Diphosphate. CAS No. 79441-34-2. Molecular formula: C10H16N6O11P2. Mole weight: 458.22. | |
| Guanosine 5'-monophosphate | Guanosine 5'-monophosphate is a purine ribonucleoside 5'-monophosphate having guanine as the nucleobase. It has a role as a metabolite, a biomarker, an Escherichia coli metabolite and a mouse metabolite. It is a guanosine 5'-phosphate and a purine ribonucleoside 5'-monophosphate. It is a conjugate acid of a guanosine 5'-monophosphate(2-). Guanosine 5 '-monophosphate is a guanine nucleotide containing one phosphate group, which is esterified into the sugar moiety and widely found in nature. Synonyms: 5-Guanylic Acid; 5'-GMP; GMP; Guanidine Monophosphate; Guanosine 5'-Phosphate; Guanosine 5'-Phosphoric Acid; Guanosine Monophosphate; Guanylic Acid. Grade: ≥95%. CAS No. 85-32-5. Molecular formula: C10H14N5O8P. Mole weight: 363.22. | |
| Guanosine 5'-monophosphate calcium salt | Calcium guanylate is a compound with formula Ca(C10H12O4N5PO4). It is the calcium salt of guanylic acid. As a food additive, it is used as a flavor enhancer and has the E number E629. Synonyms: Calcium 5'-guanylate; Guanylic acid calcium salt; calcium,[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate; 5'-Guanylic acid calcium salt; Calcium guanylate; Calcium 5'-O-phosphonatoguanosine. Grade: ≥ 95%. CAS No. 38966-30-2. Molecular formula: C10H12CaN5O8P. Mole weight: 401.28. | |
| Guanosine 5'-monophosphate disodium salt | Disodium guanylate, also known as sodium 5'-guanylate and disodium 5'-guanylate, is a natural sodium salt of the flavor enhancing nucleotide guanosine monophosphate (GMP). Disodium guanylate is a food additive with the E number E627. It is commonly used in conjunction with glutamic acid (monosodium glutamate, MSG). As it is a fairly expensive additive, it is not used independently of glutamic acid; if disodium guanylate is present in a list of ingredients but MSG does not appear to be, it is likely that glutamic acid is provided as part of another ingredient such as a processed soy protein complex. It is often added to foods in conjunction with disodium inosinate; the combination is known as disodium 5'-ribonucleotides. Disodium guanylate is produced from dried seaweed and is often added to instant noodles, potato chips and other snacks, savory rice, tinned vegetables, cured meats, and packaged soup. Synonyms: Disodium guanylate; Disodium GMP; Disodium 5'-gmp; GMP disodium salt; 5'-Gmp disodium salt; Disodium guanosine-5'-monophosphate; 5'-Guanylic acid disodium salt; Sodium 5'-guanylate; Guanosine 5'-phosphate disodium salt. Grade: 98%. CAS No. 5550-12-9. Molecular formula: C10H12N5Na2O8P. Mole weight: 407.18. | |
| Guanosine 5'-monophosphate disodium salt [1',2',3',4',5'-13C5] | Guanosine 5'-monophosphate disodium salt [1',2',3',4',5'-13C5]. Molecular formula: 13C5C5H12N5O8P·2Na. Mole weight: 412.64. | |
| Guanosine 5'-Monophosphate Ester 6-Deoxytalose Sodium Salt | Guanosine 5'-Monophosphate Ester 6-Deoxytalose Sodium Salt is used in the synthetic preparation of nucleoside monophosphate sugars such as GMP-Fucose. Synonyms: 5'-Guanylic Acid Mono(6-deoxy-α-L-galactopyranosyl) Ester Sodium Salt. Molecular formula: C16H23N5NaO12P. Mole weight: 531.34. | |
| Guanosine-5'-monophosphate triethylammonium salt | Guanosine-5'-monophosphate triethylammonium salt is an indispensable biomedical compound, displays inhibitory efficacy against a wide spectrum of diseases such as cancer and autoimmune disorders. This extraordinary therapeutic exemplar meticulously regulates intricate cellular signaling cascades while actively stimulating prosperous cellular proliferation. Molecular formula: C22H44N7O8P. Mole weight: 565.61. | |
| Guanosine 5-monophosphomorpholidate | Guanosine 5-monophosphomorpholidate - an invaluable biomedical product - finds its application in the treatment of various diseases. As a precursor for synthesizing targeted drugs against viral infections and cancerous cells, it showcases its remarkable potential. Notably, this compound plays a pivotal role in signaling pathways, guiding and governing vital cellular processes concerning DNA synthesis and repair. Its multifaceted involvement in these intricate mechanisms underscores its significance in the realm of biomedical sciences. Synonyms: N,N'-Dicyclohexylmorpholine-4-carboximidamide ((2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl morpholinophosphonate; guanosine 5'-monophospho morpholidate 4-morpholine-N,N'-dicyclohexylcarboxamidine salt; Guanosine 5'-monophosphomorpholidate 4-morpholine-N,N'-dicyclohexylcarboxamidine salt, ~95%; Guanosine 5'-monophosphomorpholidate-4-morpholine-N,N'-dicyclohexylcarboxamidine salt; (Z)-N,N'-dicyclohexylmorpholine-4-carboximidamide; {[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(morpholin-4-yl)phosphinic acid; N,N'-Dicyclohexylmorpholine-4-carboximidamide--5'-O-[hydroxy(morpholin-4-yl)phosphoryl]guanosine (1/1). Grade: 95%. CAS No. 7361-7-1. Molecular formula: C31H52N9O9P. Mole weight: 725.8. | |
| Guanosine-5'-O-(1-Thiotriphosphate) | Guanosine-5'-O-(1-Thiotriphosphate) emerges as an indispensable compound within the biomedical industry serving as a substrate for diverse enzymatic reactions and a biophysical research instrument. Throughout investigations concerning GTP-binding proteins, signal transduction pathways and protein-protein interactions, its vital participation becomes apparent. Moreover, its utilization enables the exploration of key mechanisms involved in debilitating diseases, exemplified by cancer and neurological disorders. Synonyms: Alpha Thiol GTP; 1-Thio-GTP; Guanosine-5'-Rp-Alpha-Thio-Triphosphate. Grade: ≥90% by AX-HPLC. CAS No. 81570-50-5. Molecular formula: C10H16N5O13P3S. Mole weight: 539.3. | |
| Guanosine 5'-O-(1-thiotriphosphate) lithium salt | Guanosine 5'-O-(1-thiotriphosphate) lithium salt is an exquisite compound ubiquitous in the biomedical arena aiding in studying a myriad of diseases intricately intertwined with cellular signaling and nucleotide metabolism. Within the realm of scientific exploration, it frequently serves as an indispensable tool for unraveling the mysteries enshrouding G-protein coupled receptor signaling cascades, as well as delving into the profound impact guanine nucleotides bestow upon fundamental cellular phenomena like cellular proliferation and differentiation. Synonyms: a-Thio-GTP. Molecular formula: C10H16N5O13P3S·4Li. Mole weight: 567.01. | |
| Guanosine-5'-O-(2-thiodiphosphate) | GDP-βS is guanosine 5'-O-(2-thiodiphosphate), a modified form of guanosine diphosphate (GDP) where the oxygen in the β-phosphate position is replaced by a sulfur atom. It is commonly used as a non-hydrolyzable analog of GDP in biochemical studies to investigate GTPase activity, signal transduction pathways, and molecular mechanisms involving GTP-binding proteins (G proteins). Synonyms: 5'-Guanylic acid, anhydride with phosphorothioic acid (1:1); 5'-Guanylic acid, monoanhydride with phosphorothioic acid; GDP-βS; Guanosine 5'-(β-thiodiphosphate); Guanosine 5'-O-(2-thiodiphosphate); Guanosine 5'-O-(β-thiodiphosphate); Guanyl-5'-yl thiophosphate. Grade: ≥90% by HPLC. CAS No. 71376-97-1. Molecular formula: C10H15N5O10P2S. Mole weight: 459.27. | |
| Guanosine 5'-O-(2-Thiodiphosphate) Sodium Salt | Guanosine 5'-O-(2-Thiodiphosphate) Sodium Salt is a crucial compound acting as a potent inhibitor of G proteins, essential for cellular signal transduction. This product aids in research relating to G protein-coupled receptors (GPCRs), G protein-linked signaling pathways and their associated diseases such as cancer, neurodegenerative disorders and cardiovascular diseases. Synonyms: Gdp(Beta-S) Sodium Salt; GDP-Beta-S Sodium Salt; Guanyl-5'-yl Thiophosphate Sodium Salt; GDP-BS Sodium Salt; Guanosine 5'-(Trihydrogen 3-Thiodiphosphate) Sodium Salt. Molecular formula: C10H15N5O10P2S (free acid). Mole weight: 459.27 (free acid). | |
| Guanosine 5'-O-(2-Thiodiphosphate) Trilithium Salt | Guanosine 5'-O-(2-Thiodiphosphate) Trilithium Salt is a GDP analog which could inhibits G-protein activation. Synonyms: 5'-Guanylic acid, monoanhydride with phosphorothioic acid, trilithium salt; EINECS 308-328-9; Guanosine 5'-O-(2-thiodiphosphate) trilithium salt; trilithium; [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dioxidophosphinothioyl phosphate; Guanosine 5'-[beta-thio]diphosphate trilithium salt; GDP-beta-S-Li3; GDPbetaS trilithium salt; Guanosine 5'-O-(2-Thiodiphosphate), Trilithium Salt; MFCD00057735; Guanosine 5-O-(2-thiodiphosphate)trilithium salt; Guanosine,5'-esterwith thiodiphosphoric acid([(ho)2p(o)]2s)(9ci); Guanosine 5'-[beta-thio]diphosphate trilithium salt, >=85% (HPLC), powder. CAS No. 97952-36-8. Molecular formula: C10H12Li3N5O10P2S. Mole weight: 477.07. | |
| Guanosine, 5'-?O-?[bis(4-?methoxyphenyl)?phenylmethyl]?-?2'-?O-?[(1,?1-?dimethylethyl)?dimethylsilyl]?-?N-?(2-?methyl-?1-?oxopropyl)?-?4'-?thio- | Guanosine, 5'-O-[bis(4-methoxyphenyl)?phenylmethyl]?-2'-O-[(1,?1-dimethylethyl)?dimethylsilyl]?-N-(2-methyl-1-oxopropyl)?-4'-thio- is an exceptionally intricate and groundbreaking biomedical compound meticulously engineered to inhibit malignancy cells and impede their exponential growth by intricately obstructing vital signaling pathways profoundly involved in the relentless advancement of malignant tumors. CAS No. 2080404-29-9. Molecular formula: C41H51N5O7SSi. Mole weight: 786.02. | |
| Guanosine, 5'-?O-?[bis(4-?methoxyphenyl)?phenylmethyl]?-?3'-?O-?[(1,?1-?dimethylethyl)?dimethylsilyl]?-?N-?(2-?methyl-?1-?oxopropyl)?-?4'-?thio- | Compound XYZ is a biomedical compound embodied with remarkable antioxidant and anti-inflammatory prowess, aiding in studying cancer, cardiovascular diseases and neurodegenerative disorders. CAS No. 2080404-28-8. Molecular formula: C41H51N5O7SSi. Mole weight: 786.02. | |
| Guanosine-5'-O-monophosphorothioate | Guanosine-5'-O-monophosphorothioate is a critical biomolecular compound with broad utilization for studying viral infections, cancer and neurodegenerative ailments. Synonyms: GMPS; 5'-O-thiophosphonoguanosine; 5'-GMPS. CAS No. 76310-16-2. Molecular formula: C10H14N5O7PS. Mole weight: 379.29. | |
| Guanosine 5'-Pyrophosphate Ester 6-Deoxytalose (>90%) Disodium Salt | Guanosine 5'-Pyrophosphate Ester 6-Deoxytalose has been used to study guanosine diphosphate-4-keto-D-rhamnose reductase enzyme catalysis. Synonyms: P'-(6-Deoxy-α-D-talopyranosyl) Ester Guanosine 5'-(Trihydrogen Diphosphate) Disodium Salt; Mono(6-deoxy-α-D-talopyranosyl) Ester Guanosine 5'-(Trihydrogen Pyrophosphate) Disodium Salt; Guanosine 5'-Pyrophosphate, Ester α-D-6-Deoxytalopyranosyl Disodium Salt; 6-Deoxytalopyranose 1-Ester Guanosine 5'-(Trihydrogen Pyrophosphate) Disodium Salt. Molecular formula: C16H23N5Na2O15P2. Mole weight: 633.31. | |
| Guanosine 5'-(tetrahydrogen triphosphate) sodium salt | Guanosine 5'-(tetrahydrogen triphosphate) Trisodium Salt, is the salt form of GTP, which is a substrate for the RNA synthesis during the transcription process or DNA during DNA replication. It is also used as an energy source for protein synthesis and gluconeogenesis. Synonyms: GTP Sodium Salt; 5'-GTP Sodium Salt; Sodium GTP; Guanosine 5'-(tetrahydrogen triphosphate), sodium salt (1:x); Guanosine 5'-triphosphate sodium salt; Guanosine triphosphate sodium salt. Grade: 80%. CAS No. 24905-71-3. Molecular formula: C10H16N5O14P3.xNa. Mole weight: 523.18 (free acid). | |
| Guanosine 5'-triphosphate | Guanosine triphosphate (GTP) is a guanine nucleotide containing three phosphate groups esterified to the sugar moiety. GTP functions as a carrier of phosphates and pyrophosphates involved in channeling chemical energy into specific biosynthetic pathways. GTP activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation, and activation of several intracellular kinase cascades. Proliferation and apoptosis are regulated in part by the hydrolysis of GTP by small GTPases Ras and Rho. Another type of small GTPase, Rab, plays a role in the docking and fusion of vesicles and may also be involved in vesicle formation. In addition to its role in signal transduction, GTP also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA. Synonyms: D-Guanosine 5'-triphosphate; Guanosine triphosphate; Guanosine 5'-triphosphoric acid; pppG; guanosine 5'-O-(triphosphate); [[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate. Grade: ≥98% by AX-HPLC. CAS No. 86-01-1. Molecular formula: C10H16N5O14P3. Mole weight: 523.18. | |
| Guanosine 5'-triphosphate tetrasodium salt | Guanosine 5'-triphosphate tetrasodium salt is a paramount compound in the biomedical sector, serving as a pivotal precursor engendering diverse enzymatic reactions. Notably, it finds ubiquitous employment in research laboratories to elucidate G-protein coupled receptor signaling pathways, cellular energy transference and signal transduction mechanisms. Synonyms: GTP tetrasodium salt; Tetrasodium guanosine triphosphate; Tetrasodium 5'-O-({[(phosphonatooxy)phosphinato]oxy}phosphinato)guanosine; Guanosine, 5'-(tetrahydrogen triphosphate), sodium salt (1:4); Guanosine 5'-(tetrahydrogen triphosphate), tetrasodium salt; Guanosine triphosphate tetrasodium salt. Grade: ≥97% by HPLC. CAS No. 14356-96-8. Molecular formula: C10H12N5Na4O14P3. Mole weight: 611.11. | |
| Guanosine 5'-triphosphoric acid disodium salt | GTP could be used as a phosphoryl donor in signal transduction and protein synthesis. Synonyms: GTP-Na2; Guanosine 5'-(tetrahydrogen triphosphate) sodium salt (1:2); Guanosine 5'-(tetrahydrogen triphosphate) disodium salt; 5'-GTP disodium salt; Disodium 5'-GTP; Disodium guanosine triphosphate; GTP disodium salt; Guanosine 5'-triphosphoric acid disodium salt. Grade: ≥90% by HPLC. CAS No. 56001-37-7. Molecular formula: C10H14N5Na2O14P3. Mole weight: 567.14. | |
| Guanosine Hydrate | A nucleic acids constituent. Synonyms: 2-Amino-1,9-dihydro-9-β-D-ribofuranosyl-6H-purin-6-one; DL-Guanosine; Guanine Ribonucleoside; 9-β-D-Ribofuranosylguanine; 2-Aminoinosine; NSC 19994; Vernine. Grade: 98%. CAS No. 141433-61-6. Molecular formula: C10H13N5O5xH2O. Mole weight: 283.24. | |
| Guanosine (N-iBu) | Guanosine (N-iBu) is an indispensable compound employed in biomedical investigation and pharmacological advancements assuming a pivotal stance in studying an assortment of ailments encompassing cancer, neurodegenerative conditions and viral afflictions. Grade: ≥ 98% by HPLC. Molecular formula: C14H19N5O6. Mole weight: 353.33. | |
| Guanosine (N-PAC) | Guanosine (N-PAC), a petite yet significant molecule, finds extensive applications in the biomedical industry. Its capacity to serve as a precursor in the synthesis of nucleotides, facilitating the biosynthesis of DNA and RNA, is unparalleled. The treatment of viral infections, particularly hepatitis C and dengue fever, is another area where Guanosine (N-PAC) has proved its efficacy. Interestingly, studies reveal its potential in addressing neurological disorders like Parkinson's disease - a promising avenue indeed. Grade: ≥ 98% by HPLC. Molecular formula: C18H19N5O7. Mole weight: 417.37. | |
| Guanosine (N-Phenyl acetyl) | Guanosine (N-Phenyl acetyl) is a chemical compound used in biomedical research for its potential anti-cancer properties. It has shown promise in inhibiting cell growth and inducing apoptosis in cancer cells. It is also used in the development of certain antiviral drugs due to its ability to inhibit viral replication. Grade: ≥ 98% by HPLC. Molecular formula: C18H19N5O6. Mole weight: 401.37. | |
| Guanoxabenz | Guanoxabenz, a metabolite of guanaben, is an α2 adrenergic receptor agonist. Synonyms: 2-[(E)-(2,6-dichlorophenyl)methylideneamino]-1-hydroxyguanidine; 1-(2,6-dichlorobenzylideneamino)-3-hydroxyguanidine; guanoxabenz; guanoxabenz hydrochloride; guanoxabenz monohydrochloride. CAS No. 24047-25-4. Molecular formula: C8H8Cl2N4O. Mole weight: 247.08. | |
| Guanoxabenz hydrochloride | Guanoxabenz hydrochloride is an α2 adrenergic receptor agonist, with a Ki of 4000 nM and the fully activated form 40 nM for an α2A adrenoceptor. Synonyms: 3-((2,6-Dichlorophenyl)methylene)-N-hydroxycarbazamidine monohydrochloride; Guanoxaben HCl; Hydroxyguanabenz hydrochloride. CAS No. 27818-21-9. Molecular formula: C8H9Cl3N4O. Mole weight: 283.54. | |
| Guanoxyfen sulfate | Guanoxyfen sulfate is an inhibitor of vasoconstrictor responses to sympathetic nerve stimulation. It could potentiate the actions of adrenaline and noradrenaline. It also could increase the blood glucose concentration and decrease the appetite. Uses: Guanoxyfen could potentiate the actions of adrenaline and noradrenaline. it also could increase the blood glucose concentration and decrease the appetite. Synonyms: PD-34799 hemisulfate; PPG hemisulfate; (3-Phenoxypropyl)guanidine sulfate; (3-Phenoxypropyl)guanidine hemisulfate. Grade: >98 %. CAS No. 1021-11-0. Molecular formula: C20H32N6O6S. Mole weight: 484.57. | |
| Guanylyl-(3',5')-adenosine | Guanylyl-(3',5')-adenosine, a cyclic nucleotide second messenger, intricately orchestrates various cellular signaling pathways, rendering it crucial in regulating a myriad of physiological functions, ranging from neurotransmitter release to smooth muscle contraction. A versatile molecule of interest, this compound boasts promising potential in the therapeutic arena, especially for treating cardiovascular diseases, such as hypertension and heart failure, thanks to its adeptness in modulating platelet activation and gene expression. Synonyms: GmpA; Guanine ribonucleotidyl-(3'-5')-adenosine; Adenylyl-(5',3')-guanosine; GpA RNA Dinucleotide (5'-3'); GpA; Guanylyladenosine. Grade: ≥95% by AX-HPLC. CAS No. 6554-00-3. Molecular formula: C20H25N10O11P. Mole weight: 612.45. | |
| Guanylyl-3'-5'-adenosine triethylammonium salt | Guanylyl-3'-5'-adenosine triethylammonium salt is a versatile biomedical compound employed extensively within the pharmaceutical sector, emerging as a pivotal substrate for the esteemed guanylyl cyclase enzymes. This quintessential compound finds widespread utilization in an array of fundamental biochemical and pharmacological investigations, encompassing the study of cyclic GMP signaling cascade, neuropeptide release and the inducement of smooth muscle relaxation. Synonyms: GpA. Molecular formula: C20H25N10O11P·xC6H15N. Mole weight: 612.45 (free acid). | |
| Guanylyl-(3'-5')-cytidine | Guanylyl-3',5'-cytidine, a biochemical compound, is a valuable tool in the biomedical industry for delving deep into the intricacies of RNA capping mechanisms. It mimics guanosine 5-triphosphate (GTP), a naturally occurring molecule, and is utilized to investigate the cellular processes of various RNA viruses, including hepatitis C virus (HCV). Furthermore, guanylyl-3',5'-cytidine holds the promise of therapeutic benefits for HCV and other RNA viral infections. Synonyms: Guanylyl-3',5'-cytidine; Guanylyl-(3',5')-cytidine; GpC RNA Dinucleotide (5'-3'); Cytidylyl-(5'->3')-guanosine; 3'-Guanylic acid, 5'-ester with cytidine; Guanosine, cytidylyl-(5'→3')-; Guanylyl-(3'→5')-cytidine; GC; GpC. Grade: 95%. CAS No. 4785-04-0. Molecular formula: C19H25N8O12P. Mole weight: 588.42. | |
| Guanylyl-3'-5'-cytidine ammonium salt | Guanylyl-3'-5'-cytidine ammonium salt is an indispensable compound with sector assuming a pivotal role in the research of multifarious afflictions such as neoplastic disorders and rampant viral invasions. By virtue of its indispensability, this invaluable compound serves as an indispensable implement for nucleotide synthesand RNA molecular construction. Synonyms: GpC; [5-(2-amino-6-oxo-3H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl][5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate,azane. Grade: 98%. CAS No. 98046-67-4. Molecular formula: C19H25N8O12P·NH3. Mole weight: 605.46. | |
| Guanylyl-(3'-5')-guanosine | Guanylyl-(3'-5')-guanosine is a highly significant compound extensively employed in biomedical research, emerging as an indispensable player in signal transduction. Its pivotal role lies in its capacity to function as a second messenger molecule, especially in the modulation of cyclic GMP levels. Diverse cellular phenomena, encompassing vasodilation, neurotransmission and immune responses is are meticulously investigated utilizing this molecule to scrutinize the cGMP-dependent pathways. Synonyms: GpG RNA Dinucleotide (5'-3'); 3'-Guanylic acid, 3',5'-ester with guanosine; Guanylyl-(3'→5')-guanosine; GmpG; GpG; Guanosyl(3',5')guanosine. Grade: ≥95% by AX-HPLC. CAS No. 3353-33-1. Molecular formula: C20H25N10O12P. Mole weight: 628.45. | |
| Guanylyl-3',5'-guanosine ammonium salt | Guanylyl-3',5'-guanosine ammonium salt is a vital reagent used in the biomedicine industry. It acts as a substrate in various enzymatic reactions involving guanylyltransferases, catalyzing the formation of mRNA caps. This product plays a crucial role in studying mRNA processing, capping, and gene expression. Additionally, it is used for investigating diseases related to mRNA capping abnormalities, such as cancer and viral infections. Synonyms: Guanosine, guanylyl-(3'→5')-, monoammonium salt; ((2R,3S,4R,5R)-5-(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl ((2R,3S,4R,5R)-5-(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl) hydrogen phosphate, monoammonium salt; 5'-O-[3'-Guanosyl(ammonium)phosphono]guanosine. CAS No. 97403-87-7. Molecular formula: C20H25N10O12P.H3N. Mole weight: 645.48. | |
| Guanylyl-(3'-5')-uridine | Guanylyl-(3'-5')-uridine is a dinucleotide derivative that participates in RNA capping processes. It is involved in the addition of a guanosine cap to the 5' end of RNA molecules during RNA processing, essential for mRNA stability and translation initiation. It is utilized in biochemical and molecular biology research to investigate RNA-related processes, including RNA capping mechanisms, mRNA processing, and interactions with RNA-binding proteins. This compound serves as a valuable tool in elucidating the roles of modified nucleotides in RNA biology and in studying enzymatic reactions involving RNA molecules. Synonyms: GmpU; Guanylyl(3'-5')uridine; 3'-Guanylic acid, 5'-ester with uridine; Guanosine, uridylyl-(5'→3')-; Guanylyl-(3'→5')-uridine; GU; Guanosyl-(3',5')-uridine; Guanylyl-(3',5')-uridine; NSC 92173; GU dinucleotide. Grade: ≥98%. CAS No. 4785-7-3. Molecular formula: C19H24N7O13P. Mole weight: 589.41. | |
| Guanylyl-3'-5'-uridine ammonium salt | Guanylyl-3'-5'-uridine ammonium salt is an essential biomedical ingredient, playing a pivotal role in mRNA synthesand facilitates genetic information translation. Its diverse applications span the biomedical field, notably encompassing mRNA-related disease researchs and the advancement of mRNA-based therapies. Synonyms: GpU; [5-(2-amino-6-oxo-3H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl][5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate,azane. Grade: 98%. CAS No. 41547-83-5. Molecular formula: C19H24N7O13P·NH3. Mole weight: 606.45. | |
| Guar gum | Guar gum is a galactomannan, commonly used in cosmetics, food products, and pharmaceutical formulations. It has also been investigated in the preparation of sustained-release matrix tablets in the place of cellulose derivatives such as methylcellulose. Synonyms: Galactosol; guar flour; guar galactomannanum; jaguar gum; Meyprogat; Meyprodor; Meyprofin. CAS No. 9000-30-0. | |
| GUB09-145 | GUB09-145 is a dual analog of the insulinotropic hormone GLP-1 and the intestinotropic hormone GLP-2. It can reduce body weight and improve glucose homeostasis as a Roux-en-Y gastric bypass (RYGB) mimetic, which is effective treatment modalities for obesity. GUB09-145 exhibits a long-acting activity and the potential to cure obesity and diabetes. Uses: The potential treatment of obesity and diabetes. Synonyms: GUB09 145; GUB09145. | |
| Gue 1654 | Gue 1654 is an oxoeicosanoid receptor 1 (OXE-R) modulator selectively inhibiting Gβγ but not Gαi signaling upon activation of the Gαi-βγ heterotrimer by OXE-R. Gue 1654 was shown to inhibit Gβγ-mediated opening of GIRK1/2 channels in HEK293 cells. Synonyms: Gue1654; Gue 1654; Gue-1654. N-[7-(Methylthio)benzo[1,2-d:4,3-d']bisthiazol-2-yl]-α-phenylbenzeneacetamide. Grade: ≥97% by HPLC. CAS No. 397290-30-1. Molecular formula: C23H17N3OS3. Mole weight: 447.6. | |
| Gum arabic | Gum Arabic is an exudate gum picked from Acacia trees (typically Acacia Senegal and Acacia Laetia) that grow in arid regions. The polysaccharide is branched with a main chain of (1-3) linked β-D-galactopyranosyl units with side chains of (1-3) β-D galactopyranosyl units joined to it by (1-6) links. The side chains are 2-5 units in length. Both the main chain and the side chains have attached units of α-L-arabinofuranosyl, α-L-rhamnopyranosyl, β-D-glucuronopyranosyl and 4-O-methyl-β-D-glucuronopyranosyl units. Uses: Decorative cosmetics. Synonyms: Acacia ampliceps gum; Acacia dealbata gum; Acacia fragilis gum; Acacia gum; Acacia leptopetala gum; Acacia ligulata gum; Acacia meisneri gum; Acacia pruinocarpa gum; Acacia salicina gum; Acacia senegal gum; Acacia syrup; Acacia victoriae gum; Arabic Cool; Arabic gum; Arabic Gum A; Arabicum rubber; Australian gum; Cape gum; Chaargund; Char goond; Efficacia M; Fibregum; Gum acacia; Gum ovaline; Gum senegal; Gum thala; Gums, acacia; Gundar gum; Inagel Arabia Gum A; Indian gum; Instangum IRX; Instant Gum AA; Khair gum; Kordofan gum; Maklai gum; Meska; MS 1 (gum); San Arabic; Seneca gum; Senegal gum; Ticacia Gum; Tikashi Gum; Valgum; Wattle gum. CAS No. 9000-1-5. | |
| Gum cassia tora | Gum cassia tora. | |
| Gum karaya | Gum Karaya is a vegetable gum produced from the exudate of the sterculia trees. Gum Karaya is an acidic polysaccharide composed of galactose, rhamnose and galacturonic acid. It is used in food as a thickener and emulsifier, and as a laxative and denture binder. Synonyms: E 416; Karaya gum; Gums, karaya; Gums, sterculia; Indian tragacanth gum; Inolaxol; Kadai gum; Kadaya gum; Karaya K 5; Karayacol; Katilo gum; Kullo gum; Lamegum; Mucara; Siltex gum; Sterculia BP; Sterculia gum; Tab gum. CAS No. 9000-36-6. | |
| Gunagratinib | Gunagratinib is a tyrosine kinase inhibitor, with antineoplastic activity. Synonyms: 3-[(3,5-dimethoxyphenyl)ethynyl]-5-(methylamino)-1-[(3S)-1-(prop-2-enoyl)pyrrolidin-3-yl]-1H-pyrazole-4-carboxamide; (S)-1-(1-acryloylpyrrolidin-3-yl)-3-((3,5-dimethoxyphenyl)ethynyl)-5-(methylamino)-1H-pyrazole-4-carboxamide. CAS No. 2211082-53-8. Molecular formula: C22H25N5O4. Mole weight: 423.47. | |
| Guretolimod | Guretolimod is an agonist of Toll-like receptor 7 (TLR7) with potential immunostimulatory and antineoplastic activities. Synonyms: Glycine, N-[[4-[[2-amino-4-[[(1S)-1-(2-hydroxyethyl)butyl]amino]-6-methyl-5-pyrimidinyl]methyl]-3-methoxyphenyl]methyl]-N-(2,2,2-trifluoroethyl)-; (S)-2-((4-((2-amino-4-(1-hydroxyhexan-3-ylamino)-6-methylpyrimidin-5-yl)methyl)-3-methoxybenzyl)(2,2,2-trifluoroethyl)amino)acetic acid. Grade: ≥90%. CAS No. 1488364-57-3. Molecular formula: C24H34F3N5O4. Mole weight: 513.55. | |
| Gusacitinib hydrochloride | Gusacitinib hydrochloride is a dual inhibitor of spleen tyrosine kinase (SYK) and janus kinase (JAK) with an IC50 value of 5-46 nM. It has anticancer activity. Synonyms: ASN002 hydrochloride; ASN 002 hydrochloride; ASN-002 hydrochloride. Grade: 98% by HPLC. CAS No. 2228989-14-6. Molecular formula: C24H29ClN8O2. Mole weight: 497.0. | |
| guselkumab | guselkumab is a selectively blocking agent for interleukin-23 (IL-23), a cytokine involved in plaque psoriasis. guselkumab was approved by FDA as an anti-inflammatory drug for the treatment of moderate to severe plaque psoriasis. Uses: Anti-inflammatory drug. Synonyms: Tremfya. CAS No. 1350289-85-8. Molecular formula: C6402H9864N1676O1994S42. Mole weight: 143.6. | |
| Gusperimus | Gusperimus is a derivative of the antitumor antibiotic spergualin with immunosuppressant activity. Gusperimus inhibits the interleukin-2-stimulated maturation of T cells to the S and G2/M phases and the polarization of the T cells into IFN-gamma-secreting Th1 effector T cells, resulting in the inhibition of growth of activated naive CD4 T cells; this agent may suppress growth of certain T-cell leukemia cell lines. Uses: Immunosuppressive agents. Synonyms: deoxyspergualin; Deoxyspergualin Hydrochloride; Gusperimus Trihydrochloride; BMS-181173; BMS181173; BMS 181173; BMY-42215-1; BMY 42215 1; NKT-01; NKT 01; NKT01. CAS No. 104317-84-2. Molecular formula: C17H37N7O3. Mole weight: 387.52. | |
| Gusperimus trihydrochloride | Gusperimus is a derivative of the anti-tumor antibiotic spergualin, which has immunosuppressive activity. Synonyms: Spanidin; NKT-01. Grade: 98%. CAS No. 85468-01-5. Molecular formula: C17H37N7O3.3HCl. Mole weight: 496.91. | |
| Gut restricted-7 | Gut restricted-7 is a covalent and orally active pan-bile salt hydrolase (BSH) inhibitor. It decreases gut bacterial BSHs and decreases deconjugated bile acid levels in the feces of mice. Synonyms: GR-7. Grade: 99%. CAS No. 2553218-46-3. Molecular formula: C25H40FNaO6S. Mole weight: 495.64. | |
| GV-196771 | GV-196771, an indole derivative, has been found to be a non-opioid analgesic agent which is also a NMDA antagonist binds to glycine-binding site and was once studied in pain therapy. Synonyms: GV-196771; GW-196771; GV 196771; GW 196771; GV196771; GW196771; AC1OC7O7; SCHEMBL499308; 4,6-dichloro-3-[(E)-(2-oxo-1-phenylpyrrolidin-3-ylidene)methyl]-1H-indole-2-carboxylic acid; GV196771A; GV 196771A; GV-196771A. Grade: 98%. CAS No. 166974-22-7. Molecular formula: C20H14Cl2N2O3. Mole weight: 401.24. | |
| GV-196771A | GV-196771A, the sodium salt form of GV196771, is an antagonist of NMDA receptor. Synonyms: Monosodium 4,6-dichloro-3-((E)-(2-oxo-1-phenyl-3-pyrrolidinylidene)methyl)-1H-indole-2-carboxylate; 1H-Indole-2-carboxylic acid, 4,6-dichloro-3-((E)-(2-oxo-1-phenyl-3-pyrrolidinylidene)methyl)-, monosodium salt. Grade: ≥95%. CAS No. 166974-23-8. Molecular formula: C20H13Cl2N2NaO3. Mole weight: 423.22. | |
| GV-58 | GV-58, a pupin derivative, has been found to be a P/Q-type Ca²?-channel agonist that could be used to against neuromuscular weakness. IC50: 7.21/8.81 uM (N-type/P-Q-type Ca2+ channel). Uses: Gv-58 has been found to be a p/q-type ca²?-channel agonist that could be used to against neuromuscular weakness. Synonyms: GV-58; CS-3617; GV 58; CS 3617; GV58; CS3617; CHEMBL2206242; SCHEMBL17628602; BDBM50400564. Grade: 98%. CAS No. 1402821-41-3. Molecular formula: C18H26N6OS. Mole weight: 374.50. | |
| GVK-904 | GVK-904 is an inhibitor of Trk-A with high selectivity for wild-type cancers. GVK-904 is a non-ATP-competitive inhibitor. It can be used to treat cancers induced by Trk-A. Uses: Antitumor drug. Synonyms: GVK 904; GVK904. | |
| GW0742 | GW0742 is a potent and highly selective PPARβ/δ agonist, with IC50 of 1 nM, with 1000-fold selectivity over hPPARα and hPPARγ. Synonyms: GW0742; GW-0742; GW 0742; GW0742X; GW-0742X; GW 0742X; GW610742; GW-610742; GW 610742. Grade: >98%. CAS No. 317318-84-6. Molecular formula: C21H17F4NO3S2. Mole weight: 471.49. | |
| GW-1100 | A cell-permeable pyrimidinylmethyl-pyrimidinone compound that acts as potent, reversible and non-competitive GPR40 antagonist. Shown to significantly reverse glucose-induced insulin secretion potentiated by GW9508 and only partially reduce linoleic acid effect in MIN6 cells. Synonyms: GW 1100; GW-1100; GW1100. Grade: >98%. CAS No. 306974-70-9. Molecular formula: C27H25FN4O4S. Mole weight: 520.58. | |
| GW1929 | A potent, tyrosine-based peroxisome proliferator-activated receptor γ (PPARγ) agonist (EC50 = 13 nM for murine receptor and 6.2 nM for human receptor in cell-based transactivation assays). Synonyms: GW 1929; GW-1929. Grade: >98%. CAS No. 196808-24-9. Molecular formula: C30H29N3O4. Mole weight: 495.57. | |
| GW 1929 hydrochloride | GW 1929 hydrochloride is a selective and orally bioactive agonist of peroxisome proliferator-activated receptor (PPAR)γ (pEC50 = 8.05, < 4 and < 4 for human PPARγ, PPARα and PPARδ receptors, respectively). GW 1929 causes a decrease of glucose, fatty acid and triglyceride levels following oral administration in vivo. Synonyms: GW 1929 hydrochloride; GW1929 hydrochloride; GW-1929 hydrochloride; N-(2-Benzoylphenyl)-O-[2-(methyl-2-pyridinylamino)ethyl]-L-tyrosine hydrochloride; (2S)-2-(2-benzoylanilino)-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]propanoic acid hydrochloride. Grade: ≥98% by HPLC. CAS No. 1217466-21-1. Molecular formula: C30H29N3O4.HCl. Mole weight: 532.03. | |
| GW2580 | GW2580 is an orally bioavailable inhibitor of cFMS kinase. GW2580 was found to completely inhibit human cFMS kinase in vitro at 0.06 microM and was inactive against 26 other kinases. GW2580 at 1 microM completely inhibited CSF-1-induced growth of mouse M-NFS-60 myeloid cells and human monocytes and completely inhibited bone degradation in cultures of human osteoclasts, rat calvaria, and rat fetal long bone. In contrast, GW2580 did not affect the growth of mouse NS0 lymphoblastoid cells, human endothelial cells, human fibroblasts, or five human tumor cell lines. GW2580 also did not affect lipopolysaccharide (LPS)-induced TNF, IL-6, and prostaglandin E2 production in freshly isolated human monocytes and mouse macrophages. After oral administration, GW2580 blocked the ability of exogenous CSF-1 to increase LPS-induced IL-6 production in mice, inhibited the growth of CSF-1-dependent M-NFS-60 tumor cells in the peritoneal cavity, and diminished the accumulation of macrophages in the peritoneal cavity after thioglycolate injection. Unexpectedly, GW2580 inhibited LPS-induced TNF production in mice, in contrast to effects on monocytes and macrophages in vitro. In conclusion, GW2580's selective inhibition of monocyte growth and bone degradation is consistent with cFMS kinase inhibition. The ability of GW2580 to chronically inhibit CSF-1 signaling through cFMS kinase in normal and tumor cells in vivo makes GW2580 a useful tool in assessing | |
| GW 274150 | GW 274150 is a potent, long-acting and highly selective inhibitor of iNOS which have a very high degree of selectivity for iNOS versus both eNOS (>100-fold) and nNOS (>80-fold). GW 274150 shows analgesic effects in rat models of inflammatory and neuropath. Synonyms: (2S)-2-amino-4-[2-(1-aminoethylideneamino)ethylsulfanyl]butanoic acidGW-274150; GW 274150; GW274150. CAS No. 210354-22-6. Molecular formula: C8H17N3O2S. Mole weight: 219.30. | |
| GW274150 phosphate | GW274150 phosphate is a selective, orally active, and NADPH-dependent inhibitor of human inducible nitric oxide synthase (iNOS) (IC50: 2.19 μM; Kd: 40 nM) and rat iNOS (ED50: 1.15 μM). Grade: 98%. CAS No. 438542-15-5. Molecular formula: C8H20N3O6PS. Mole weight: 317.30. | |
| GW280264X | GW280264X is a potent inhibitor of ADAM17 and ADAM10 inhibitor with IC50 of 8 nM and 11.5 nM, respectively. It prevents in vivo germ cell apoptosis induced by BPA or NP. Grade: >98%. CAS No. 866924-39-2. Molecular formula: C28H41N5O6S. Mole weight: 575.7. | |
| GW284543 | GW284543 (UNC10225170) is a selective MEK5 inhibitor. It can reduce pERK5 and reduce endogenous MYC protein. Synonyms: CHEMBL531447; BCP31359; MFCD32067894; HY-114189. Grade: 98%. CAS No. 790186-68-4. Molecular formula: C23H20N2O3. Mole weight: 372.4. | |
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