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Helioxanthin
Helioxanthin and its analogues decreased cellular RNA levels of HBV and antigen expression as well as selective inhibition of HBV replication in a cell culture model. Helioxanthin analogue 8-1 exhibited anti-DHBV activity as demonstrated by quantification of viral DNA, RNA, covalently closed circular DNA and protein synthesis. Analogue 8-1 did not affect the stability of cellular macromolecules and did not have a sustained antiviral effect after drug removal. When DHBV replication was induced, virus-harbouring cells were more susceptible to the cytotoxicity of 8-1 than non-induced cells. Synonyms: ACH-126447; ACH 126447; ACH126447; HE-145; HE 145; HE145. Helioxanthin. Grade: >98%. CAS No. 18920-47-3. Molecular formula: C20H12O6. Mole weight: 348.31.
Helioxanthin 8-1
Helioxanthin 8-1 is an analogue of helioxanthin, which exhibites significant in vitro anti-HBV/HCV/HSV-1/HIV activity. It showed the most potent antiHBV activity among those helioxanthin analogues tested. It exhibited moderately potent activity against HIV and effective inhibition on DHBV replication. It would therefore be promising to study helioxanthin analogues that contain a six-membered ring instead of the five-membered ring found in the lactam. Synonyms: Helioxanthin 8 1; Helioxanthin analogue 8-1; Helioxanthin analogue 8 1. Grade: >98%. CAS No. 840529-13-7. Molecular formula: C20H12N2O6. Mole weight: 376.32.
Helioxanthin derivative 5-4-2
Helioxanthin derivative 5-4-2 had potent anti-HBV activities in HepG2.2.15 cells, with the EC50s of 1 and 0.08 microM, respectively. The lamivudine-resistant HBV, L526M/M550V double mutant strain, was also sensitive to helioxanthin and 5-4-2. This class of compounds not only inhibited HBV DNA, but also decreased HBV mRNA and HBV protein expression. The EC50 of HBV DNA inhibition was consistent with the EC50 of HBV 3.5 Kb transcript inhibition, which was 1 and 0.09 microM for helioxanthin and 5-4-2 respectively. Synonyms: Helioxanthin 5-4-2; Helioxanthin 5 4 2. Grade: >98%. CAS No. 203935-39-1. Molecular formula: C20H13NO5. Mole weight: 347.32.
Hellebrigenin
Hellebrigenin is an anticancer agent that induces DNA damage, mitochondria collapse, cell cycle arrest and apoptosis. Synonyms: Bufotalidin; (3S,5S,8R,9S,10S,13R,14S,17R)-3,5,14-trihydroxy-13-methyl-17-(6-oxopyran-3-yl)-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-10-carbaldehyde. CAS No. 465-90-7. Molecular formula: C24H32O6. Mole weight: 416.514.
HEMADO
HEMADO is a selective and high affinity adenosine A3 receptor agonist (Ki = 1.1, 327, 1230 and > 30,000 nM for human A3, A1, A2A and A2B receptors, respectively). Synonyms: 2-(1-Hexynyl)-N-methyladenosine. Grade: ≥99% by HPLC. CAS No. 403842-38-6. Molecular formula: C17H23N5O4. Mole weight: 361.4.
Hematein
Hematein is a stain for the cell nuclei of animal tissue. Hematein is an allosteric casein kinase II inhibitor with an IC50 of 0.74 μM. Hematein inhibits Akt/PKB Ser129 phosphorylation, the Wnt/TCF pathway and increases apoptosis in lung cancer cells. Synonyms: 6a,7-Dihydro-3,4,6a,10-tetrahydroxybenz[b]indeno[1,2-d]pyran-9(6H)-one; Haematein; 3,4,6a,10-Tetrahydroxy-6a,7-dihydroindeno[2,1-c]chromen-9(6H)-one. CAS No. 475-25-2. Molecular formula: C16H12O6. Mole weight: 300.26.
Hematoporphyrin
Hematoporphyrin is a substrate for affinity chromatography of heme-binding proteins. Synonyms: Photodyn; Sensibion. Grade: >98%. CAS No. 14459-29-1. Molecular formula: C34H38N4O6. Mole weight: 598.69.
Hematoporphyrin dihydrochloride
Hematoporphyrin dihydrochloride is a substrate for affinity chromatography of heme-binding proteins. Hematoporphyrin dihydrochloride induces apoptosis in U87 glioma cells and decrease tumor growth in vivo when exposed to red light. Synonyms: Hematoporphyrin IX Dihydrochloride; 7,12-bis(1-Hydroxyethyl)-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoic Acid Dihydrochloride. Grade: ≥98%. CAS No. 17696-69-4. Molecular formula: C34H40Cl2N4O6. Mole weight: 671.61.
Hematoporphyrin monomethyl ether
Hematoporphyrin monomethyl ether is characterized by its single form, high yield of singlet oxygen, high selectivity, and low toxicity, which has been widely used in the diagnosis and treatment of various tumors, including lung cancer, bladder cancer, and nevus flammeus and brain glioma. Synonyms: 8-(1-Hydroxyethyl)-13-(1-methoxyethyl)-3,7,12,17-tetramethyl-21H,23H-porphyrin-2,18-dipropionic acid. CAS No. 148471-91-4. Molecular formula: C35H40N4O6. Mole weight: 612.72.
Heme Oxygenase-1-IN-1
Heme Oxygenase-1-IN-1 is an inhibitor of heme oxygenase 1 (HO-1) with an IC50 of 250 nM. Synonyms: HO-1-IN-1; 1-[4-(4-bromophenyl)butyl]-1H-imidazole. Grade: 98%. CAS No. 1093058-52-6. Molecular formula: C13H15BrN2. Mole weight: 279.18.
Heme Oxygenase-1-IN-1 hydrochloride
Heme Oxygenase-1-IN-1 hydrochloride is an inhibitor of heme oxygenase 1 (HO-1) with an IC50 of 250 nM. Synonyms: HO-1-IN-1 hydrochloride; 1-[4-(4-bromophenyl)butyl]-1H-imidazole hydrochloride. Grade: 99%. CAS No. 1092851-70-1. Molecular formula: C13H16BrClN2. Mole weight: 315.63.
Heme Oxygenase-1-IN-2
Heme Oxygenase-1-IN-2 is a novel heme oxygenase-1 inhibitor (IC50 = 0.95 μM) with potent in vitro antiproliferative activity. Molecular formula: C19H18ClN3O. Mole weight: 339.82.
Hemicellulose
Hemicellulose is a complex polysaccharide found in plant cell walls, playing a crucial role in the structural integrity and flexibility of plant tissues. Unlike cellulose, which is made up of long chains of glucose, hemicellulose consists of a diverse mixture of sugars, including xylose, mannose, galactose, and arabinose, arranged in branched chains. It is a major component of plant cell walls, often found alongside cellulose and lignin. Hemicellulose is soluble in alkaline solutions but not in water, and it can be broken down into simpler sugars by hydrolysis. It is used in various industries, including paper and pulp, as a natural binder and stabilizer, and in the food industry, where it serves as a dietary fiber and texture modifier. Its ability to interact with other polysaccharides and proteins makes it an important factor in the functionality and processing of plant-based materials. Synonyms: Bakezyme Real X; Carubin; Cellace; Cellace 25; E 426; Hemilose; Hemixylan; Nisshoku Cellace; Polyosen; Psyllium hemicellulose. Semicellulose; SM 1200; SM 660; SM 700; SM 900; SM 920; Soya-Up M 800; Soyafibe S-DN; Soyafibe S-EN 100; SSHC; Xylan Ax. Grade: ≥95%. CAS No. 9034-32-6.
Hemokinin 1 (human) acetate
Hemokinin 1 (human) acetate is an endogenous substance P homolog and acts as a selective agonist at the tachykinin NK1 receptors (IC50 = 1.8, 370 and 480 nM for NK1, NK3 and NK2 receptors, respectively). It induces the proliferation of B-cells in vitro and exhibits antihypertensive activity in vivo. Synonyms: L-Threonylglycyl-L-lysyl-L-alanyl-L-seryl-L-glutaminyl-L-phenylalanyl-L-phenylalanylglycyl-L-leucyl-L-methioninamide acetate; Human hemokinin 1 acetate; H-Thr-Gly-Lys-Ala-Ser-Gln-Phe-Phe-Gly-Leu-Met-NH2.CH3CO2H. Grade: ≥95%. Molecular formula: C56H88N14O16S. Mole weight: 1245.45.
Hemokinin 1, human TFA
Hemokinin 1, human TFA is a selective tachykinin neurokinin 1 (NK1) receptor full agonist. It can produce an opioid-independent analgesia. Synonyms: Hemokinin 1 (human) (trifluoroacetate salt); L-threonylglycyl-L-lysyl-L-alanyl-L-seryl-L-glutaminyl-L-phenylalanyl-L-phenylalanylglycyl-L-leucyl-L-methioninamide, trifluoroacetate salt. Grade: 95%. Molecular formula: C56H85F3N14O16S. Mole weight: 1299.42.
Hemopressin (rat)
Hemopressin (rat) is a bioactive endogenous peptide substrate for endopeptidase 24.15, neurolysin and ACE (Ki = 27.76, 3.43 and 1.87 μM, respectively). Hemopressin (rat) acts as a selective CB1 receptor inverse agonist with antinociceptive and hypotensive activity. Synonyms: hemopressin; Hemopressin (rat); 568588-77-2; Hemopressin(rat); CHEMBL510801; PVNFKFLSH; DTXSID301029393; HY-P1090; BDBM50242451; AKOS024456765; CS-0027673; Q5712532; (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-3-methyl-2-[[(2S)-pyrrolidine-2-carbonyl]amino]butanoyl]amino]-4-oxobutanoyl]amino]-3-phenylpropanoyl]amino]hexanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoic acid. CAS No. 568588-77-2. Molecular formula: C53H77N13O12. Mole weight: 1088.27.
Hemopressin (rat) acetate
Hemopressin (rat) is a bioactive endogenous peptide substrate for endopeptidase 24.15, neurolysin and ACE (Ki = 27.76, 3.43 and 1.87 μM, respectively). Hemopressin (rat) acts as a selective CB1 receptor inverse agonist with antinociceptive and hypotensive activity. Molecular formula: C5H81N13O14. Mole weight: 1148.31.
Hemorphin-7 acetate
Hemorphin-7, a hemorphin peptide with antinociceptive and antihypertensive effects, is an endogenous opioid peptide derived from the β-chain of hemoglobin. Hemorphin peptides activates opioid receptors and inhibits angiotensin-converting enzyme (ACE). The much lower affinity of hemorphin-7 for μ-receptors as compared to other opioid peptides may be compensated by its much higher plasma concentration, resulting in biological effects of comparable magnitude. Molecular formula: C51H68N12O13. Mole weight: 1057.16.
Henagliflozin
Henagliflozin, a glucoside compound, has been found to be a sodium-glucose transporter 2 inhibitor that could probably be effective in hyperglycaemic. It is under Phase I trial against Type-2 diabetes mellitus. Synonyms: UNII-21P2M98388; 21P2M98388; Henagliflozin; SHR3824; SHR-3824; SHR 3824; (1R,2S,3S,4R,5R)-5-[4-chloro-3-[(4-ethoxy-3-fluorophenyl)methyl]phenyl]-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol. Grade: 98%. CAS No. 1623804-44-3. Molecular formula: C22H24ClFO7. Mole weight: 454.88.
Henatinib
Henatinib inhibits vascular endothelial growth factor receptor type 2 (VEGFR2), a tyrosine kinase receptor upregulated in many tumor cells that plays a key role in angiogenesis. This may result in an inhibition of angiogenesis and eventually tumor cell proliferation. Henatinib, structurally similar to sunitinib, also inhibits, though to a lesser extent, mast/stem cell growth factor receptor (c-Kit) and, platelet-derived growth factor receptor (PDGFR) alpha and beta. Synonyms: (R,Z)-2-(5-fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-5-(2-hydroxy-3-morpholin-4-yl-propyl)-3-methyl-5,6,7,8-tetrahydro-1H-pyrrolo[3,2-c]azepin-4-one. CAS No. 1239269-51-2. Molecular formula: C25H29FN4O4. Mole weight: 468.53.
Heneicosapentaenoic acid
Heneicosapentaenoic acid (HPA) is a 21:5 ω-3 fatty acid found in the green alga B. pennata and in fish oils. HPA is incorporated into phospholipids and into triacylglycerol in cell culture and inhibits the conversion of linolenic acid to arachidonic acid (AA) in hepatoma cells. HPA is a poor substrate for prostaglandin H synthase (PGHS) (cyclooxygenase) and for 5-lipoxygenase. Synonyms: HPA; (all-Z)-6,9,12,15,18-heneicosapentaenoic acid; (6Z,9Z,12Z,15Z,18Z)-6,9,12,15,18-henicosapentaenoic acid. Grade: ≥95%. CAS No. 24257-10-1. Molecular formula: C21H32O2. Mole weight: 316.5.
Heneicosapentaenoic acid methyl ester
Heneicosapentaenoic acid methyl ester is a derivative of heneicosapentaenoic acid (HPA), a 21:5 ω-3 fatty acid found in the green alga B. pennata and in fish oils. HPA is incorporated into phospholipids and into triacylglycerol in cell culture and inhibits the conversion of linolenic acid to arachidonic acid (AA) in hepatoma cells. HPA is a poor substrate for prostaglandin H synthase (PGHS) (cyclooxygenase) and for 5-lipoxygenase. Synonyms: HPA methyl ester; Methyl 6,9,12,15,18-heneicosapentaenoate; (all-Z)-6,9,12,15,18-heneicosapentaenoic acid methyl ester; (6Z,9Z,12Z,15Z,18Z)-6,9,12,15,18-henicosapentaenoic acid methyl ester. Grade: ≥98%. CAS No. 65919-53-1. Molecular formula: C22H34O2. Mole weight: 330.5.
Heparamine, sodium salt
It is a derivative of porcine mucosal heparin without anticoagulant properties. Synonyms: De-N-sulfated heparin (Heparin I-H) sodium salt; De-N-sulfated heparin sodium salt. CAS No. 61932-66-9.
Heparan Sulfate
Heparan sulfate, a complex and linear polysaccharide in which the backbone is composed of repeating sulfated disaccharide units, exists as part of glycoproteins named heparan sulfate proteoglycans, which are expressed abundantly on the cell surface and in the extracellular matrix. Synonyms: Alpha-idosane; HHS 5; Heparan N-Sulfate; Heparan Sulfate; Heparan Sulphate; Heparitin; Heparitin Monosulfate; N-Acetylheparan Sulfate; Suleparoid; Tavidan. CAS No. 9050-30-0. Molecular formula: (C24H30N2O39S6)n.
Heparan sulphate sodium salt
Heparan sulphate sodium salt. CAS No. 57459-72-0.
Heparin
Heparin, a highly sulfated glycosaminoglycan, is widely used as an injectable anticoagulant, and has the highest negative charge density of any known biological molecule. The common form is the sodium salt form. Synonyms: [2-Deoxy-2-sulfoamino-6-O-sulfo-4-O-(2-O-sulfo-a-L-idopyranuronosyl)-a-D-glucopyranose]n; Adomiparin; Ardeparin; Arteven; AVE 5026; Bemiparin; Centaxarin; Certoparin; Clevarin; Clivarin; Clivarine; CY 216; CY 222; Dalteparin; Deligoparin; F 202; Fluxum; FR 860; Fragmin A; Fragmin B; Fraxiparin; Gammaparin; H 5284; H 9399; Hapacarin; Heparin subcutan; Heparin sulfate; Heparinic acid; Heparins; KB 101; Leparan; LipoHep Forte; Livaracine; M 118; M 402 (heparin); Mono-embolex; Multiparin; Nadroparin; Nadroparine; Necuparanib; Novoheparin; Octaparin; OP 386; OP 622; Pabyrn; Parnaparin; Parvoparin; Reviparin; Sandoparin; Semuloparin; Subeparin; Sublingula; Tafoxiparin; Tinzaparin; Triofiban; Vetren; Vitrum AB; α-Heparin. Grade: >98%. CAS No. 9005-49-6.
Heparin Binding Peptide
Heparin Binding Peptide, a heparin-binding peptide isolated from a proteolytic hydrolysate of bovine lactoferrin, increase the endothelialisation of prosthetic materials in vitro. Synonyms: Trp-Gln-Pro-Pro-Arg-Ala-Arg-Ile; WQPPRARI. Molecular formula: C47H74N16O10. Mole weight: 372.69.
Heparin derived dp10 saccharide ammonium salt
Heparin derived dp10 saccharide ammonium salt is an esteemed compound, aiding in the research of thrombosand cardiovascular ailments. Synonyms: Decasaccharide dp10; Decasaccharide (dp10). Mole weight: ~3000 (Average).
Heparin derived dp12 Saccharide ammonium salt
Heparin derived dp12 Saccharide ammonium salt is an innovative biomedical solution originating from heparin, showcasing its exceptional efficacy in studying thrombosand embolism. Its profound anticoagulant characteristics pave the way for its utilization in studying the intricate realm of cardiovascular diseases and hemodialysis. Synonyms: Dodecasaccharide dp12; Dodecasaccharide (dp12). Mole weight: ~3550 (Average).
Heparin derived dp14 saccharide ammonium salt
Heparin derived dp14 saccharide ammonium salt, a derivative of heparin, is renowned as an esteemed anticoagulant compound. It finds vital applicability in the research of antithrombotic therapeutic approaches. Synonyms: Tetradecasaccharide dp14; Tetradecasaccharide (dp14). Mole weight: ~4100 (Average).
Heparin derived dp16 saccharide ammonium salt
Heparin derived dp16 saccharide ammonium salt is a pharmaceutical compound, finding widespread application in studying conditions like deep vein thrombosand pulmonary embolism. Synonyms: Hexadecasaccharide dp16; Hexadecasaccharide (dp16). Mole weight: ~4650 (Average).
Heparin derived dp18 saccharide ammonium salt
Heparin derived dp18 saccharide ammonium salt is a biomedical product used in the research of blood clotting disorders. This compound, synthesized from heparin, exhibiting anticoagulant properties. Mole weight: ~ 5200 (average).
Heparin derived dp20 saccharide ammonium salt
Heparin derived dp20 saccharide ammonium salt is a sophisticated biomedical compound employed for the research of hemostatic dysfunctions and cardiovascular pathologies. Unveiling from Heparin origin, this compound exhibits anticoagulative attributes. Mole weight: ~5750 (Average).
Heparin derived dp22 saccharide ammonium salt
Heparin derived dp22 saccharide ammonium salt is an intriguing derivative arising from heparin, which is a formidable anticoagulant. Imbued with an intricate dp22 saccharide configuration, this structure augments its bioactive potential. The ammonium salt manifestation of this compound begets bolstered solubility and bioavailability. Mole weight: ~6300 (Average).
Heparin derived dp24 saccharide ammonium salt
Heparin-derived dp24 saccharide ammonium salt is a biomedically utilized product, serving to study blood clotting disorders. It originates from heparin and comprises dp24 saccharide ammonium salt. Mole weight: Average 6850.
Heparin derived dp26 saccharide ammonium salt
Heparin derived dp26 saccharide ammonium salt is a biomedical product used in the treatment of blood clotting disorders. It is derived from heparin, a naturally occurring anticoagulant, and exhibits potent antithrombotic properties. This product helps prevent the formation of blood clots and is commonly used in the management of deep vein thrombosis, pulmonary embolism, and other related conditions. Molecular formula: C156H207N13O247S39Na52. Mole weight: 8662.29.
Heparin derived dp4 saccharide
Heparin derived dp4 saccharide, a biomedical compound derived from heparin, showcases profound therapeutic potential in treating blood clotting disorders and cardiovascular ailments. With its distinctive attributes as a dp4 saccharide ammonium salt, it exemplifies great efficacy in averting thrombosis and mitigating associated complexities. Synonyms: Tetrasaccharide (dp4); D-Glucose, O-2-O-sulfo-α-L-idopyranuronosyl-(1→4)-O-2-deoxy-6-O-sulfo-2-(sulfoamino)-β-D-glucopyranosyl-(1→4)-O-2-O-sulfo-α-L-idopyranuronosyl-(1→4)-2-deoxy-2-(sulfoamino)-, 6-(hydrogen sulfate). CAS No. 61844-85-7. Molecular formula: C24H40N2O39S6. Mole weight: 1172.96.
Heparin derived dp6 saccharide ammonium salt
Heparin derived dp6 saccharide ammonium salt is a biomedical product derived from heparin that can be used to study blood clotting disorders. This saccharide ammonium salt exhibits potent anticoagulant properties. Synonyms: Heparin hexasaccharide. Mole weight: ~1800 (Average).
Heparin derived dp8 saccharide ammonium salt
Heparin derived dp8 saccharide ammonium salt is a biomedical product used in the research of thrombosand coagulation disorders. This drug, derived from heparin, exhibits anticoagulant properties by inhibiting certain clotting factors in the blood. Synonyms: Octasaccharide dp8; Octasaccharide (dp8). Mole weight: ~2400 (Average).
Heparin disaccharide I-A trisodium salt
It is a minor component produced from heparin by heparinase II. Synonyms: alpha-DeltaUA-2S-[1->4]-GlcNAc-6S; α-δUA-2S-[1->4]-GlcNAc-6S; D-glucose, 2-(acetylamino)-2-deoxy-4-O-(4-deoxy-2-O-sulfo-α-L-threo-hex-4-enopyranuronosyl)-, 6-(hydrogen sulfate), sodium salt (1:3); Trisodium 2-acetamido-2-deoxy-4-O-(4-deoxy-2-O-sulfonato-α-L-threo-hex-4-enopyranuronosyl)-6-O-sulfonato-D-glucose; 2-(Acetylamino)-2-deoxy-4-O-(4-deoxy-2-O-sulfo-α-L-threo-hex-4-enopyranuronosyl)-D-glucose 6-(hydrogen sulfate), sodium salt (1:3); D-Glucose, 2-(acetylamino)-2-deoxy-4-O-(4-deoxy-2-O-sulfo-α-L-threo-hex-4-enopyranuronosyl)-, 6-(hydrogen sulfate), trisodium salt. Grade: ≥95%. CAS No. 136098-00-5. Molecular formula: C14H18NNa3O17S2. Mole weight: 605.39.
Heparin disaccharide I-H trisodium salt
It is the major component from the action of heparinase II on de-N-sulfated heparin. Synonyms: Heparin unsaturated disaccharide I-H trisodium salt; alpha-DeltaUA-2S-[1->4]-GlcN-6S; Trisodium 2-amino-2-deoxy-4-O-(4-deoxy-2-O-sulfonato-alpha-L-threo-hex-4-enopyranuronosyl)-6-O-sulfonato-D-glucose; 2-Amino-2-deoxy-4-O-(4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronosyl)-D-glucose 6-(hydrogen sulfate) trisodium salt; α-δUA-2S-[1->4]-GlcN-6S; D-Glucose, 2-amino-2-deoxy-4-O-(4-deoxy-2-O-sulfo-α-L-threo-hex-4-enopyranuronosyl)-, 6-(hydrogen sulfate), trisodium salt. Grade: 95%. CAS No. 136098-04-9. Molecular formula: C12H16NNa3O16S2. Mole weight: 563.35.
Heparin disaccharide II-A disodium salt
It is a product of the action of heparinases II and III on heparin and heparin sulfate. Synonyms: Disodium 2-acetamido-2-deoxy-4-O-(4-deoxy-α-L-threo-hex-4-enopyranuronosyl)-6-O-sulfonato-D-glucopyranose; 2-(Acetylamino)-2-deoxy-4-O-(4-deoxy-alpha-L-threo-hex-4-enopyranuronosyl)-D-glucose 6-(hydrogen sulfate) disodium salt. Grade: ≥95%. CAS No. 136098-06-1. Molecular formula: C14H19NO14SNa2. Mole weight: 503.34.
Heparin disaccharide II-H disodium salt
Heparin disaccharide II-H disodium salt is the major component from the action of heparinase II on de-N-sulfated heparin. Synonyms: Heparin unsaturated disaccharide II-H disodium salt; Sodium (2R,3R,4S)-2-(((2R,3S,4R,5R)-5-amino-2,4-dihydroxy-6-oxo-1-(sulfonatooxy)hexan-3-yl)oxy)-3,4-dihydroxy-3,4-dihydro-2H-pyran-6-carboxylate; D-Glucose, 2-amino-2-deoxy-4-O-(4-deoxy-α-L-threo-hex-4-enopyranuronosyl)-, 6-(hydrogen sulfate), sodium salt (1:2); Alpha-delta-ua-[1->4]-GlcN-6S sodium salt; D-Glucose, 2-amino-2-deoxy-4-O-(4-deoxy-α-L-threo-hex-4-enopyranuronosyl)-, 6-(hydrogen sulfate), disodium salt. Grade: ≥98%. CAS No. 136098-02-7. Molecular formula: C12H17NNa2O13S. Mole weight: 461.31.
Heparin disaccharide III-A disodium salt
It is a minor product of the action of heparinase II on heparin. Synonyms: Disodium 2-acetamido-2-deoxy-4-O-(4-deoxy-2-O-sulfonato-α-L-threo-hex-4-enopyranuronosyl)-D-glucopyranose; 2-(Acetylamino)-2-deoxy-4-O-(4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronosyl)-D-glucose disodium salt. Grade: ≥95%. CAS No. 136098-11-8. Molecular formula: C14H19NNa2O14S. Mole weight: 503.34.
Heparin disaccharide III-H disodium salt
It is the major component from the action of heparinase II on de-N-sulfated heparin. Synonyms: alpha-DeltaUA-2S-[1->4]-GlcN; α-δua-2s-[1→4]-glcn; Disodium 2-amino-2-deoxy-4-O-(4-deoxy-2-O-sulfonato-α-L-threo-hex-4-enopyranuronosyl)-D-glucopyranose; D-Glucose, 2-amino-2-deoxy-4-O-(4-deoxy-2-O-sulfo-α-L-threo-hex-4-enopyranuronosyl)-, disodium salt; 2-Amino-2-deoxy-4-O-(4-deoxy-2-O-sulfo-α-L-threo-hex-4-enopyranuronosyl)-D-glucose disodium salt. Grade: ≥95%. CAS No. 136098-01-6. Molecular formula: C12H17NNa2O13S. Mole weight: 461.31.
Heparin disaccharide III-S trisodium salt
It is produced from heparin by digestion with heparinase I and II. Synonyms: Alpha-delta-ua-2s-[1->4]-glcns sodium salt; Sodium (2R,3R,4S)-4-hydroxy-3-(sulfonatooxy)-2-(((2R,3S,4R,5R)-1,2,4-trihydroxy-6-oxo-5-(sulfonatoamino)hexan-3-yl)oxy)-3,4-dihydro-2H-pyran-6-carboxylate; Trisodium 2-deoxy-4-O-(4-deoxy-2-O-sulfonato-α-L-threo-hex-4-enopyranuronosyl)-2-(sulfonatoamino)-D-glucose; D-Glucose, 2-deoxy-4-O-(4-deoxy-2-O-sulfo-α-L-threo-hex-4-enopyranuronosyl)-2-(sulfoamino)-, sodium salt (1:3); 2-Deoxy-4-O-(4-deoxy-2-O-sulfo-α-L-threo-hex-4-enopyranuronosyl)-2-(sulfoamino)-D-glucose sodium salt (1:3); D-Glucose, 2-deoxy-4-O-(4-deoxy-2-O-sulfo-α-L-threo-hex-4-enopyranuronosyl)-2-(sulfoamino)-, trisodium salt. Grade: ≥95%. CAS No. 136098-03-8. Molecular formula: C12H16NNa3O16S2. Mole weight: 563.35.
Heparin disaccharide II-S trisodium salt
It is produced from heparinase II digestion of heparin and heparin sulphate. Synonyms: 2-Deoxy-4-O-(4-deoxy-α-L-threo-hex-4-enopyranuronosyl)-2-(sulfoamino)-D-glucose 6-(Hydrogen sulfate) Trisodium Salt; Alpha-delta-ua-[1->4]-glcns-6S sodium salt; Trisodium 2-deoxy-4-O-(4-deoxy-α-L-threo-hex-4-enopyranuronosyl)-6-O-sulfonato-2-(sulfonatoamino)-D-glucose; D-Glucose, 2-deoxy-4-O-(4-deoxy-α-L-threo-hex-4-enopyranuronosyl)-2-(sulfoamino)-, 6-(hydrogen sulfate), sodium salt (1:3); 2-Deoxy-4-O-(4-deoxy-α-L-threo-hex-4-enopyranuronosyl)-2-(sulfoamino)-D-glucose 6-(hydrogen sulfate) sodium salt (1:3); D-Glucose, 2-deoxy-4-O-(4-deoxy-α-L-threo-hex-4-enopyranuronosyl)-2-(sulfoamino)-, 6-(hydrogen sulfate), trisodium salt. CAS No. 136098-05-0. Molecular formula: C12H16NNa3O16S2. Mole weight: 563.35.
Heparin disaccharide I-P trisodium salt
It is prepared from heparin unsaturated disaccharide I-H by n-propionylation. It is a homologue of disaccharide I-A with the inclusion of a methylene group in the amide acyl group. It does not occur in nature and was devised as an internal standard for HPLC, CZE and CE analysis of heparin/heparin sulfate. It is also ideally suited as an internal standard for HLPC/CZE analysis of chondroitin series, after digestion with chondroitinases. Synonyms: Heparin unsaturated disaccharide I-P trisodium salt; (α-δUA-2S-[1→4]-GlcNCOEt-6S); 2-Deoxy-3-O-[(1R)-4-deoxyhex-4-enopyranuronosyl]-2-(propionylamino)-D-glycero-hexopyranose trisodium salt; D-Glucose, 2-deoxy-4-O-(4-deoxy-2-O-sulfo-α-L-threo-hex-4-enopyranuronosyl)-2-[(1-oxopropyl)amino]-, 6-(hydrogen sulfate), trisodium salt. Grade: 95%. CAS No. 149368-05-8. Molecular formula: C15H20NNa3O17S2. Mole weight: 619.42.
Heparin disaccharide I-S, tetrasodium salt
It is a predominant disaccharide produced from heparin by heparinase I and II. Synonyms: 2-Deoxy-4-O-(4-deoxy-2-O-sulfo-α-L-threo-hex-4-enopyranuronosyl)-2-(sulfoamino)-D-glucose 6-(hydrogen sulfate) Sodium Salt; sodium (2R,3R,4S)-2-((2R,3S,4R,5R)-4,6-dihydroxy-5-(sulfonatoamino)-2-(sulfonatooxymethyl)tetrahydro-2H-pyran-3-yloxy)-4-hydroxy-3-(sulfonatooxy)-3,4-dihydro-2H-pyran-6-carboxylate; alpha-DeltaUA-2S-[1->4]-GlcNS-6S; Tetrasodium 2-deoxy-4-O-(4-deoxy-2-O-sulfonato-α-L-threo-hex-4-enopyranuronosyl)-6-O-sulfonato-2-(sulfonatoamino)-D-glucopyranose. Grade: ≥98%. CAS No. 136098-10-7. Molecular formula: C12H15NNa4O19S3. Mole weight: 665.40.
Heparin disaccharide IV-A, sodium salt
It is produced from heparin sulfate by digestion with heparinase III. Synonyms: ΔGlcAΔ(1-4)GlcNAc; sodium (2R,3R,4S)-2-((2R,3S,4R,5R)-5-acetamido-4,6-dihydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yloxy)-3,4-dihydroxy-3,4-dihydro-2H-pyran-6-carboxylate; D-Glucopyranose, 2-(acetylamino)-2-deoxy-4-O-(4-deoxy-α-L-threo-hex-4-enopyranuronosyl)-, sodium salt (1:1); α-δ-UA-[1->4]-GLCNAC; 2-(Acetylamino)-2-deoxy-4-O-(4-deoxy-α-L-threo-hex-4-enopyranuronosyl)-D-glucose sodium salt (1:1); D-Glucose, 2-(acetylamino)-2-deoxy-4-O-(4-deoxy-α-L-threo-hex-4-enopyranuronosyl)-, monosodium salt. Grade: ≥90%. CAS No. 136098-07-2. Molecular formula: C14H20NNaO11. Mole weight: 401.30.
Heparin disaccharide IV-H
It is the product of digestion of heparin sulfate and heparin by various heparinases. Synonyms: alpha-delta-UA-[1->4]-GLCN; 2-Amino-2-deoxy-4-O-(4-deoxy-α-L-threo-hex-4-enopyranuronosyl)-D-glucose; D-Glucose, 2-amino-2-deoxy-4-O-(4-deoxy-α-L-threo-hex-4-enopyranuronosyl)-. Grade: 95%. CAS No. 123228-39-7. Molecular formula: C12H19NO10. Mole weight: 337.28.
Heparin disaccharide IV-S disodium salt
It is produced from heparin sulfate by digestion with heparinase III. Synonyms: Heparin unsaturated disaccharide IV-S, disodium salt; sodium (2R,3R,4S)-2-((2R,3S,4R,5R)-4,6-dihydroxy-2-(hydroxymethyl)-5-(sulfonatoamino)tetrahydro-2H-pyran-3-yloxy)-3,4-dihydroxy-3,4-dihydro-2H-pyran-6-carboxylate; 2-Deoxy-4-O-(4-deoxy-alpha-L-threo-hex-4-enopyranuronosyl)-2-(sulfoamino)-D-glucose disodium salt; 2-Deoxy-4-O-(4-deoxy-α-L-threo-hex-4-enopyranuronosyl)-2-(sulfoamino)-D-glucose sodium salt (1:2); D-Glucose, 2-deoxy-4-O-(4-deoxy-α-L-threo-hex-4-enopyranuronosyl)-2-(sulfoamino)-, disodium salt. Grade: ≥90%. CAS No. 136098-08-3. Molecular formula: C12H17NNa2O13S. Mole weight: 461.31.
Heparin Lithium
Heparin Lithium is a mucopolysaccharide that is used primarily as an anticoagulant. Heparin binds to antithrombin III and accelerates the rate of inhibition of coagulation proteases. Synonyms: Heparin, lithium salt; Lithium acid heparin; Lithium heparin; Lithium heparinate. CAS No. 9045-22-1.
Heparinoids
Danaparoid is an anticoagulant medication used primarily for the prevention and treatment of deep vein thrombosis (DVT) and other thromboembolic disorders. It is a mixture of sulfated glycosaminoglycans, including heparan sulfate, dermatan sulfate, and chondroitin sulfate, which are derived from animal tissues. Synonyms: Heparinoid; Heparinoids and Heparinlike substances; Mucopolysaccharides, heparinoids; Danaparoid; Lomoparan; OH 10172; Orgaran. CAS No. 308068-55-5.
Heparin Sodium
Heparin sodium is a sodium salt of heparin which is a naturally-occurring anticoagulant used for anticoagulation for cardiovascular disease. It is an inhibitor of activated coagulation factors such as Factors Xa and IIa (thrombin). Uses: Anticoagulation for cardiovascular disease. Synonyms: Adomiparin Sodium; Alfa 87-120; Ardeparin Sodium; Badyket; Bemiparin Sodium; Dalteparin Sodium; Deligoparin Sodium; Depo-Heparin; Fragmin; Hepaflush; Hepagumin; Hepalean; Heprinar; Hepsal; Lipo-Hepin; Liquaemin Sodium; Logiparin; Longheparin; Minolteparin Sodium; Monoparin; Nadroparine Sodium; Normiflo; Panheprin; Parnaparin Sodium; Pularin; Reviparin Sodium; Semuloparin Sodium; Sevuparin Sodium; Sodium Acid Heparin; Sodium Heparin; Sodium Heparinate; Thrombo-Hepin. CAS No. 9041-8-1. Molecular formula: (C12H16NS2Na3)20. Mole weight: 6000-20000.
Heparin sodium salt (Low in Ca)
Heparin sodium salt (Low in Ca) is a bioactive compound with potent anticoagulant properties that are essential in managing various blood clotting disorders, including deep vein thrombosis and pulmonary embolisms. Its unique mechanism of action involves the inhibition of blood clot formation, effectively reducing the risk of further complications. This specialized Heparin sodium salt formulation contains reduced levels of calcium, thus minimizing the potential incidence of the dreaded heparin-induced thrombocytopenia (HIT) syndrome. Complex yet highly effective, this anticoagulant therapy represents a crucial medical breakthrough in ensuring patient safety and well-being.
Heparin sulfate NS-oligosaccharide NS
Heparin sulfate NS-oligosaccharide NS.
Heparin sulfate oligosaccharide NAc
Heparin sulfate oligosaccharide NAc.
Heparosan from E. coli K5
Heparosan is an endogenous Glycosaminoglycan biosynthesized and secreted by E. coli K5. Heparosan serves as the starting carbon backbone for the chemoenzymatic synthesis of heparin, a widely used clinical anticoagulant drug. Synonyms: Heparosan; Heparosan (E. coli K5). CAS No. 152324-79-3.
Hepronicate
Hepronicate is a peripheral vascular dilator that has the effect of lowering blood lipids. Synonyms: Megrin; 2-Hexyl-2-(hydroxymethyl)-1,3-propanediol trinicotinate; Hepronicatum; 2-Hydroxymethyl-2-hexyl-1,3-propanediol trinicotinate; 3-Pyridinecarboxylic acid, 2-hexyl-2-(((3-pyridinecarbonyl)oxy)methyl)-1,3-propanediyl ester; CLY 115; CLY-115; CLY115; Heptylidintrimethyl trinicotinate; 1,1,1-(Trihydroxymethyl)heptane Trinicotinate; 1,1,1-Trimethylolheptane Trinicotinate; 2,2-Bis{[(3-pyridinylcarbonyl)oxy]methyl}octyl nicotinate. Grade: ≥95%. CAS No. 7237-81-2. Molecular formula: C28H31N3O6. Mole weight: 505.56.
Hepsulfam
Hepsulfam is a bisulfamic ester which is similar in structure to busulfan and belongs to the family of drugs known as alkylsulfonate alkylating agents. Hepsulfam forms covalent linkages with nucleophilic centers in DNA, resulting in depurination, base miscoding, strand scission, DNA-DNA and DNA-protein cross-linking, and cytotoxicity. Check for active clinical trials or closed clinical trials using this agent. Synonyms: 1,7-Heptanediol disulfamate; Sulfamic acid, 1,7-heptanediyl ester; NSC-329680. CAS No. 96892-57-8. Molecular formula: C7H18N2O6S2. Mole weight: 290.35.
Heptadecanoyl coenzyme A
Heptadecanoyl-CoA is a long-chain fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of heptadecanoic acid, It has a role as a metabolite. It is a long-chain fatty acyl-CoA and an 11,12-saturated fatty acyl-CoA. It is functionally related to a heptadecanoic acid. It is a conjugate acid of a heptadecanoyl-CoA(4-). Synonyms: Heptadecanoyl-CoA. Grade: >99%. CAS No. 3546-17-6. Molecular formula: C38H68N7O17P3S. Mole weight: 1019.98.
Heptadecyl 2-acetamido-2-deoxy-b-D-glucopyranoside, a biomedical marvel, unleashes its prowess in combatting a pantheon of afflictions. Acutely skilled in the art of inhibition, it zeroes in on fortes such as precise enzyme targeting, deftly impeding the advancement of select cancers and bacterial infections. This compound, adorned with therapeutic potential, engenders a cornucopia of auspicious outcomes within preclinical realms. Synonyms: N-((2R,3R,4R,5S,6R)-2-(Heptadecyloxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)acetamide; Heptadecyl 2-(acetylamino)-2-deoxy-β-D-glucopyranoside. CAS No. 262856-90-6. Molecular formula: C25H49NO6. Mole weight: 459.66.
Heptadecyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranoside, a crucial compound in the biomedical field, exhibits significant importance. It finds extensive applications in the realm of antiviral drug development as well as the investigation of infectious diseases. Synonyms: β-D-Glucopyranoside, heptadecyl 2-(acetylamino)-2-deoxy-, 3,4,6-triacetate; (2R,3S,4R,5R,6R)-5-Acetamido-2-(acetoxymethyl)-6-(heptadecyloxy)tetrahydro-2H-pyran-3,4-diyl diacetate; Heptadecyl 2-(acetylamino)-2-deoxy-3,4,6-triacetate-β-D-Glucopyranoside. CAS No. 262856-89-3. Molecular formula: C31H55NO9. Mole weight: 585.77.
Heptakis(2,3,6-tri-O-benzoyl)cyclomaltoheptaose
Heptakis(2,3,6-tri-O-benzoyl)cyclomaltoheptaose, a derivative of cyclodextrin, presents an exceptional ability to encapsulate hydrophobic molecules, endorsing solubility and bioavailability of drugs. Its innovative therapeutic applications for cancer and drug-resistant fungal infections have been extensively researched, substantiating its potential as a vanguard drug delivery system. Synonyms: Heptakis-(2,3,6-tri-O-benzoyl)-b-cyclodextrin; β-Cyclodextrin, 2A,2B,2C,2D,2E,2F,2G,3A,3B,3C,3D,3E,3F,3G,6A,6B,6C,6D,6E,6F,6G-heneicosabenzoate; β-Cyclodextrin, heneicosabenzoate; Hepta-(2,3,6-tri-oxy-benzoyl)-β-cyclodextrin; Heptakis(2,3,6-tri-O-benzoyl)-β-cyclodextrin; β-Cyclodextrin perbenzoate; Tri-O-benzoyl-b-cyclodextrin; b-Cyclodextrin heptakis(2,3,6-tri-O-benzoate). CAS No. 23666-43-5. Molecular formula: C189H154O56. Mole weight: 3321.21.
Heptakis(2,3,6-tri-O-ethyl)cyclomaltoheptaose
Heptakis(2,3,6-tri-O-ethyl)cyclomaltoheptaose is a biomedicine product utilized in the treatment of various drug delivery systems and targeted therapies. Its applications include encapsulating and delivering drugs specifically to treat liver diseases, cancer, and other chronic conditions. With its unique structure, this product enhances drug solubility, stability, and bioavailability, fostering effective treatment outcomes. Synonyms: Heptakis-(2,3,6-tri-O-ethyl)-b-cyclodextrin; 2A,2B,2C,2D,2E,2F,2G,3A,3B,3C,3D,3E,3F,3G,6A,6B,6C,6D,6E,6F,6G-Heneicosa-O-ethyl-β-cyclodextrin; Hepta-(2,3,6-tri-oxy-ethyl)-β-cyclodextrin; Heptakis(2,3,6-tri-O-ethyl)-β-cyclodextrin; Perethylated β-cyclodextrin. CAS No. 111689-01-1. Molecular formula: C84H154O35. Mole weight: 1724.10.
Heptakis(2,3,6-tri-O-methyl)cyclomaltoheptaose
Heptakis(2,3,6-tri-O-methyl)cyclomaltoheptaose is a derivative of β-cyclodextrin, which is a solubilizing and stabilizing agent. Synonyms: Trimethyl-b-cyclodextrin; Heneicosa-O-methyl-b-cyclodextrin; 2,3,6-Tri-O-methyl-β-cyclodextrin; 2,3,6-Trimethyl-β-cyclodextrin; Cydex-β; Hepta-(2,3,6-tri-oxy-methyl)-β-cyclodextrin; Heptakis(2,3,6-tri-O-methyl)-β-cyclodextrin; Hydrodex β-PM; Me21-β-CD; Per-O-methyl-β-cyclodextrin; Permethyl-β-cyclodextrin; Tri-O-methyl-β-cyclodextrin; β-Cyclodextrin permethyl ether. Grade: ≥98%. CAS No. 55216-11-0. Molecular formula: C63H112O35. Mole weight: 1429.54.
Heptakis(2,3-di-O-acetyl-6-O-tert-butyldimethylsilyl)cyclomaltoheptaose, a highly significant compound extensively utilized in the biomedical sector, assumes a pivotal role in diverse therapeutic applications. With its remarkable capacity to effectively combat numerous afflictions, this product stands out as an indispensable entity within the realm of modern biomedical research and development. Beneath its intricately designed structure lies a potent agent capable of precisely targeting specific medications or facilitating the development of innovative drug delivery systems. Synonyms: Silyl(6-O-tert-butyldimethyl)-2,3-di-acetyl)-b-cyclodextrin; Heptakis(6-O-tert-butyldimethylsilyl)-b-cyclodextrin tetradecaacetate; β-Cyclodextrin, 6A,6B,6C,6D,6E,6F,6G-heptakis-O-[(1,1-dimethylethyl)dimethylsilyl]-, tetradecaacetate; β-Cyclodextrin, 6A,6B,6C,6D,6E,6F,6G-heptakis-O-[(1,1-dimethylethyl)dimethylsilyl]-, 2A,2B,2C,2D,2E,2F,2G,3A,3B,3C,3D,3E,3F,3G-tetradecaacetate; 2,3-Di-O-acetyl-6-O-tert-butyldimethylsilyl β-cyclodextrin; Heptakis(2,3-di-O-acetyl-6-O-tert-butyldimethylsilyl)-β-cyclodextrin; Heptakis(6-O-tert-butyldimethylsilyl-2,3-di-O-acetyl)-β-cyclodextrin; Hydrodex β-TBDAc; Silyl((6-tert-butyl-dimethyl)-2,3-di-oxy-acetyl)-β-cyclodextrin. CAS No. 123172-94-1. Molecular formula: C112H196O49Si7. Mole weight: 2523.32.
Heptakis(2,3-di-O-acetyl-6-sulfo)-beta-cyclodextrin sodium salt
Heptakis(2,3-di-O-acetyl-6-sulfo)-beta-cyclodextrin sodium salt is a remarkable biomedical compound, acting as an efficacious drug carrier. It exhibits profound capabilities in augmenting the solubility, stability and bioavailability of pharmaceutical compounds. Synonyms: β-Cyclodextrin, 2A,2B,2C,2D,2E,2F,2G,3A,3B,3C,3D,3E,3F,3G-tetradecaacetate 6A,6B,6C,6D,6E,6F,6G-heptakis(hydrogen sulfate), sodium salt (1:7). β-Cyclodextrin, 2A,2B,2C,2D,2E,2F,2G,3A,3B,3C,3D,3E,3F,3G-tetradecaacetate 6A,6B,6C,6D,6E,6F,6G-heptakis(hydrogen sulfate), heptasodium salt; Heptakis(2,3-di-O-acetyl-6-O-sulfo)-β-cyclodextrin sodium salt; Heptakis(2,3-diacetyl-6-sulfato)-β-cyclodextrin sodium salt. CAS No. 196398-66-0. Molecular formula: C70H91O70S7Na7. Mole weight: 2437.81.
Heptakis(2,3-di-O-acetyl)-β-cyclodextrin
Heptakis(2,3-di-O-acetyl)-β-cyclodextrin is an intermediate formed in the synthesis of Heptakis(6-O-sulfo)-β-cyclodextrin Heptasodium Salt, a β-Cyclodextrin derivative that inhibits anthrax lethal toxin. Chiral selector for capillary electrophorese, CE. Synonyms: Per-2,3-acetyl-β-cyclodextrin; 2A,2B,2C,2D,2E,2F,2G,3A,3B,3C,3D,3E,3F,3G-Tetradecaacetate-β-cyclodextrin; β-Cyclodextrin, 2A,2B,2C,2D,2E,2F,2G,3A,3B,3C,3D,3E,3F,3G-tetradecaacetate. CAS No. 116389-66-3. Molecular formula: C70H98O49. Mole weight: 1723.50.