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An impurity of Nintedanib, a receptor tyrosine kinase (RTK) inhibitor that binds to vascular endothelial growth factor receptor, fibroblast growth factor receptor and platelet derived growth factor receptor. Nintedanib is used as a medication for the treatment of idiopathic pulmonary fibrosis. Synonyms: N-methyl-2-(4-methyl-1-piperazinyl)-N-(4-nitrophenyl)acetamide; N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide. CAS No. 1139453-98-7. Molecular formula: C14H20N4O3. Mole weight: 292.33.
N-Methyl-3- (2-methyl-3- ( (methylamino) (phenyl)methoxy)phenoxy)-3-phenylpropan-1-amine is an impurity of Atomoxetine, which is a selective norepinephrine (NE) reuptake inhibitor for the treatment of attention-deficit hyperactivity disorder (ADHD). Synonyms: 3'-(3''-Aminomethyl-1''-phenyl-propoxy) Atomoxetine; 3,3'-[2-Methylbenzene-1,3-diyl)bis(oxy)]bis(N-methyl-3-phenylpropan-1-amine). Molecular formula: C27H34N2O2. Mole weight: 418.57.
N-Methyl-4-hydroxy-leucine
N-Methyl-4-hydroxy-leucine is an impurity of Cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: 4-Hydroxy-N-methyl-L-leucine; L-Leucine, 4-hydroxy-N-methyl-; N-methyl-gamma-hydroxyleucine; Cyclosporin Impurity 3. Grades: 96%. CAS No. 1041436-72-9. Molecular formula: C7H15NO3. Mole weight: 161.20.
N-Methylbut-2-enoate Ethyl Ester D-(-)Phenylglycine Potassium Salt
N-Methylbut-2-enoate Ethyl Ester D-(-)Phenylglycine Potassium Salt is used in the synthesis of penicillins and cephalosporins. Synonyms: (R)-α-[(3-Ethoxy-1-methyl-3-oxo-1-propenyl)amino]benzeneacetic Acid Monopotassium Salt; (αR)-α-[(3-Ethoxy-1-methyl-3-oxo-1-propenyl)amino]benzeneacetic Monopotassium Salt; D-(-)-3-[(α-Carboxybenzyl)amino]crotonic Acid 1-Ethyl Ester Monopotassium Salt; Potassium D-(1-Ethoxycarbonylpropen-2-yl)-α-aminophenylacetate; Potassium (R,E)-2-((4-ethoxy-4-oxobut-2-en-2-yl)amino)-2-phenylacetate; Potassium (R)-[(3-ethoxy-1-methyl-3-oxoprop-1-enyl)amino]phenylacetate. Grades: ≥95%. CAS No. 961-69-3. Molecular formula: C14H16KNO4. Mole weight: 301.38.
N-Methyl Etodolac
A derivative of Etodolac. Etodolac is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2. Synonyms: 1,8-Diethyl-1,3,4,9-tetrahydro-9-methylpyrano[3,4]indole-1-acetic Acid. Grades: > 95%. CAS No. 849630-94-0. Molecular formula: C18H23NO3. Mole weight: 301.39.
N-Methyl Mitomycin A
N-Methyl Mitomycin A is an intermediate of Mitocycin B. Mitomycin is a drug which is used for treatment of malignant neoplasm of lip. Synonyms: (1aS, 8S, 8aR, 8bS)-8-[[(Aminocarbonyl)oxy]methyl]-1, 1a, 2, 8, 8a, 8b-hexahydro-6, 8a-dimethoxy-1, 5-dimethylazirino[2', 3':3, 4]pyrrolo[1, 2-a]indole-4, 7-dione; [1aS-(1aα, 8β, 8aα, 8bα)]-8-[[(Aminocarbonyl)oxy]methyl]-1, 1a, 2, 8, 8a, 8b-hexahydro-6, 8a-dimethoxy-1, 5-dimethylazirino[2', 3':3, 4]pyrrolo[1, 2-a]indole-4, 7-dione; Mitomycin F; N-Methylmitomycin A; 1, 1a, 2, 8, 8a, 8b-Hexahydro-8-(hydroxymethyl)-6, 8aα-dimethoxy-1, 5-dimethylazirino[2', 3':3, 4]pyrrolo[1, 2-a]indole-4, 7-dione Carbamate. Grades: ≥95%. CAS No. 18209-14-8. Molecular formula: C17H21N3O6. Mole weight: 363.36.
An impurity of Nintedanib, a receptor tyrosine kinase (RTK) inhibitor that binds to vascular endothelial growth factor receptor, fibroblast growth factor receptor and platelet derived growth factor receptor. Nintedanib is used as a medication for the treatment of idiopathic pulmonary fibrosis. Synonyms: N-methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide; 1038972-16-5; CS-0011633; N-Methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide (Nintedanib Impurity). CAS No. 1038972-16-5. Molecular formula: C13H18N4O3. Mole weight: 278.31.
An impurity of Nintedanib, a receptor tyrosine kinase (RTK) inhibitor that binds to vascular endothelial growth factor receptor, fibroblast growth factor receptor and platelet derived growth factor receptor. Nintedanib is used as a medication for the treatment of idiopathic pulmonary fibrosis. CAS No. 2037385-84-3. Molecular formula: C13H19ClN4O3. Mole weight: 314.77.
N-Methyl Naltrexone-O-ethyl Carbonate
N-Methyl-N-formylhydrazine
N-Methyl-N-formylhydrazine is a substituent used in the synthesis of Marbofloxacin, which is a third-generation fluoroquinolone antibiotic with high bactericidal activity against a variety of aerobic Gram-negative bacteria, some Gram-positive bacteria, and Mycoplasma spp. Synonyms: 1-Formyl-1-methylhydrazine; 1-Methyl-1-formylhydrazide; 2-Methyl-2-formylhydrazine; N-Formyl-N-methylhydrazine; Formic Acid 1-Methylhydrazide; 1-Methylhydrazinecarboxaldehyde; NSC 122452. Grades: ≥95%. CAS No. 758-17-8. Molecular formula: C2H6N2O. Mole weight: 74.08.
N-Methyl Pemetrexed Dimethyl Ester
N-Methyl pemetrexed dimethyl ester is one of pemetrexed intermediates. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: Pemetrexed N-Methyl Dimethyl Ester; N-[4-[2-(2-Amino-4,7-dihydro-1-methyl-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl] L-Glutamic Acid 1,5-Dimethyl Ester. Molecular formula: C23H27N5O6. Mole weight: 469.49.
N-Methyl Pemetrexed L-Glutamic Acid
N-Methyl Pemetrexed L-glutamic acid is one of pemetrexed intermediates. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: N-{4-[2-(2-Amino-1-methyl-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}-L-γ-glutamyl-L-glutamic acid; L-Glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-1-methyl-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-γ-glutamyl-. Molecular formula: C26H30N6O9. Mole weight: 570.55.
An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Impurity 25. CAS No. 2251048-76-5. Molecular formula: C22H23N3O7S2. Mole weight: 505.56.
N,N'-Bis[2-(acetyloxy)-1-[(acetyloxy)methyl]ethyl]-5-amino-2,4,6-triiodo-1,3-benzenedicarboxamide is an intermediate of Iopamidol, which is a nonionic radiocontrast medium, used as a diagnostic aid (radiopaque medium). Uses: Intermediate in the production of iopamidol. Synonyms: 1,3-Benzenedicarboxamide, N1,N3-bis[2-(acetyloxy)-1-[(acetyloxy)methyl]ethyl]-5-amino-2,4,6-triiodo-; (5-Amino-2,4,6-triiodo-1,3-phenylene)bis(carbonylimino-2,1,3-propanetriyl)tetraacetate; ( (5-amino-2, 4, 6-triiodoisophthaloyl)bis (azanediyl))bis (propane-3, 2, 1-triyl)tetraacetate. Grades: ≥95%. CAS No. 148051-08-5. Molecular formula: C22H26I3N3O10. Mole weight: 873.17.
N,N'-bis[3-(4-Cyanophenoxy)-4-methylphenyl]urea is a derivative of Sorafenib, which is a kinase inhibitor drug used for the treatment of primary kidney cancer (advanced renal cell carcinoma), advanced primary liver cancer (hepatocellular carcinoma), FLT3-ITD positive AML and radioactive iodine resistant advanced thyroid carcinoma. Synonyms: Urea, N,N'-bis[3-(4-cyanophenoxy)-4-methylphenyl]-. Grades: 98%. CAS No. 1421677-31-7. Molecular formula: C29H22N4O3. Mole weight: 474.51.
It is an impurity of Cabozantinib. Cabozantinib is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively. Synonyms: 1,1-Cyclopropanedicarboxamide, N,N'-bis(4-((6,7-dimethoxy-4-quinolinyl)oxy)phenyl)-; Cabozantinib Impurity 01. CAS No. 2439164-91-5. Molecular formula: C39H34N4O8. Mole weight: 686.72.
It is an impurity of Cabozantinib. Cabozantinib is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively. Synonyms: Cabozantinib Impurity EXA; 1,1-Cyclopropanedicarboxamide, N,N'-bis(4-fluorophenyl)-; Cabozantinib Impurity 06. CAS No. 1431468-36-8. Molecular formula: C17H14F2N2O2. Mole weight: 316.30.
D-Homocysteine Thiolactone Hydrochloride is a derivative of L-Homocystine. Synonyms: 4,4'-Dithiobis[2-[(trifluoroacetyl)amino]-butanoic Acid Dimethyl Ester; (2S,2'S)-4,4'-Dithiobis[2-[(2,2,2-trifluoroacetyl)amino]-butanoic Acid 1,1'-Dimethyl Ester. Grades: 97%. CAS No. 84355-09-9. Molecular formula: C14H18F6N2O6S2. Mole weight: 488.42.
N,N'-Diacetyl-D-cystine
N,N'-Diacetyl-D-cystine is an intermediate in the synthesis of N-Acetyl-D-cysteine. Synonyms: (2S,2'S)-3,3'-Disulfanediylbis(2-acetamidopropanoic Acid); N-acetyl-D-cysteine (1->1')-disulfide compound with N-acetyl-D-cysteine; bis-N-acetyl D-cystine. CAS No. 97247-12-6. Molecular formula: C10H16N2O6S2. Mole weight: 324.37.
N,N-Diacetyl Des-4-fluorobenzyl Mosapride
N,N-Diacetyl Des-4-fluorobenzyl Mosapride is a metabolite of Mosapride, which is a selective agonist of 5-HT4 receptor, could be used as an astroprokinetic agent. It is also found to be a 5-HT3 receptor antagonist. Uses: Protected mosapride metabolite. Synonyms: 4-(Acetylamino)-N-[(4-acetyl-2-morpholinyl)methyl]-5-chloro-2-ethoxy-benzamide; Benzamide, 4-(acetylamino)-N-[(4-acetyl-2-morpholinyl)methyl]-5-chloro-2-ethoxy-. Grades: 97%. CAS No. 170799-32-3. Molecular formula: C18H24ClN3O5. Mole weight: 397.85.
N,N-Diacetyl Des-5'-chloro-4-fluorobenzyl Mosapride is an intermediate of Mosapride, which is a selective agonist of 5-HT4 receptor, could be used as an astroprokinetic agent. It is also found to be a 5-HT3 receptor antagonist. Uses: Intermediate in the preparation of mosapride and its metabolites. Synonyms: 4-(Acetylamino)-N-[(4-acetyl-2-morpholinyl)methyl]-2-ethoxy-benzamide; Benzamide, 4-(acetylamino)-N-[(4-acetyl-2-morpholinyl)methyl]-2-ethoxy-. Grades: 98%. CAS No. 170799-31-2. Molecular formula: C18H25N3O5. Mole weight: 363.41.
N,N-Diethyl-2-methylene-1-phenyl-cyclopropanecarboxamide is an impurity of Milnacipran, which is a serotonin-norepinephrine reuptake inhibitor (SNRI) used in the clinical treatment of fibromyalgia. Synonyms: Cyclopropanecarboxamide, N,N-diethyl-2-methylene-1-phenyl-. CAS No. 1418000-38-0. Molecular formula: C15H19NO. Mole weight: 229.32.
N,N-Diethyl-5,6,7,8-tetrahydronaphthalene-1-carboxamide is an intermediate in the synthesis of Palonosetron, which is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Synonyms: N,N-Diethyl-5,6,7,8-tetrahydro-1-naphthalenecarboxamide; 1-Naphthalenecarboxamide, N,N-diethyl-5,6,7,8-tetrahydro-. Grades: ≥95%. CAS No. 296281-84-0. Molecular formula: C15H21NO. Mole weight: 231.33.
N,N-Diethyl-5,6-dihydronaphthalene-1-carboxamide
N,N-Diethyl-5,6-dihydronaphthalene-1-carboxamide is an intermediate of Palonosetron. Palonosetron (INN, trade name Aloxi) is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Molecular formula: C15H19NO. Mole weight: 229.32.
N,N-Diethyl-8-hydroxy-5,6,7,8-tetrahydronaphthalene-1-carboxamide is an intermediate in the synthesis of Palonosetron, which is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Molecular formula: C15H21NO2. Mole weight: 247.33.
(N,N-Dimethylcarbamimidoyl)urea
(N,N-Dimethylcarbamimidoyl)urea is an impurity of metformin, a first-line drug for the treatment of type 2 diabetes. Synonyms: N,N-Dimethylamidino Urea; N3-Desamidino; N3-carbamoyl Metformin. CAS No. 98026-16-5. Molecular formula: C4H10N4O. Mole weight: 130.15.
N,N-Dimethylformamide diethyl acetal
Flumazenil Related Compound C is used as a reagent in the design of EGF-R tyrosine kinase inhibitors. lt was used in quantification of cocaine and its primary metabolite, benzoyl ecgonine from urine matrix by gas chromatography. Uses: N,n-dimethylformamide diethyl acetal is used as a reagent in the design of egf-r tyrosine kinase inhibitors. also used in the synthesis of aminopyridine derivatives. Synonyms: 1,1-diethoxy-N,N-dimethylmethanamine. Grades: > 95 %. CAS No. 1188-33-6. Molecular formula: C7H17NO2. Mole weight: 147.22.
N,N'-dimethyl-Gly-Desmopressin
N,N'-dimethyl-Gly-Desmopressin is an impurity of Desmopressin, which is a synthetic octapeptide and an analog of the human hormone arginine vasopressin with antidiuretic and coagulant activities. Synonyms: Desmopressin EP-impurity-G; Deamino-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-D-Arg-Gly-N(Me)2 (Disulfide bridge: Cys1-Cys6); deamino-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-D-arginyl-N,N'-dimethylglycine (1->6)-disulfide; Mpr-Tyr-Phe-Gln-Asn-Cys-Pro-D-Arg-Gly-N(Me)2 (Disulfide Bridge Mpr1-Cys6); deamino-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-D-arginyl-N,N'-dimenthyl-glycine (Disulfide Bridge Mpr1-Cys6). Molecular formula: C48H68N14O12S2. Mole weight: 1097.28.
N,N-Dimethylimidazole-1-sulfonamide
1-(N,N-Dimethylsulfamoyl)-1H-imidazole is an Imidazole derivative, used in the preparation of Histamine H3 Receptor Agonists and druglike angiotensin II compounds with affinity for the AT2 receptor. Synonyms: N,N-dimethyl-1-imidazolesulfonamide; 1-(N,N-Dimethylsulfamoyl)-1H-imidazole; 1-(N,N-Dimethylsulfamoyl)imidazole; Imidazole-1-sulfonic Acid Dimethylamide; N,N-Dimethyl-1H-imidazole-1-sulfonamide; N,N-Dimethylsulfamoyl-1H-imidazole; NSC 700551. Grades: >95%. CAS No. 78162-58-0. Molecular formula: C5H9N3O2S. Mole weight: 175.21.
N, N'- (Ethane-1, 2-diyl) bis (4-methyl-N- (3- ( (4-methylphenyl) sulfonamido) propyl) benzenesulfonamide)
An impurity of Plerixafor which is an antagonist of the CXCR4 chemokine receptor. Synonyms: Plerixafor Impurity 33; 4-methyl-N-[3- (4-methylbenzenesulfonamido) propyl]-N- (2-{N-[3- (4-methylbenzenesulfonamido) propyl]4-methylbenzenesulfonamido}ethyl) benzene-1-sulfonamide. CAS No. 74676-47-4. Molecular formula: C36H46N4O8S4. Mole weight: 791.03.
N-Nitorso Dabigatran Impurity 46
N-Nitorso Dabigatran Impurity 46 is an impurity of Dabigatran, an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with atrial fibrillation. Molecular formula: C8H7N3O5. Mole weight: 225.16.
N-Nitrosoanabasine HCl
N-Nitrosoanabasine HCl is a metabolite of Nicotine, which is a potent parasympathomimetic stimulant. Synonyms: N'-Nitrosoanabasine hydrochloride; 1-Nitroso-2-(3-pyridyl)piperidine hydrochloride; Nitrosoanabasine hydrochloride; 3-(1-Nitroso-2-piperidinyl)pyridine hydrochloride; Piperidine, 1-nitroso-2-(3-pyridyl)-, hydrochloride (1:1); (RS)-N-Nitrosoanabasine hydrochloride; (+-)-N-Nitrosoanabasine hydrochloride. Molecular formula: C10H13N3O.HCl. Mole weight: 227.69.
N-Nitrosocytisine
N-Nitrosocytisine is a derivative of Cytisine, which is a nicotinic acetylcholine receptor (nAChR) agonist. Synonyms: (1R,5R)-1,2,3,4,5,6-Hexahydro-3-nitroso-1,5-methano-8H-pyrido[1,2-a][1,5]diazocin-8-one; 12-Nitrosocytisine; Nitrosocytisine; 1,5-Methano-8H-pyrido[1,2-a][1,5]diazocin-8-one, 1,2,3,4,5,6-hexahydro-3-nitroso-, (1R,5R)-. Grades: ≥90%. CAS No. 19634-60-7. Molecular formula: C11H13N3O2. Mole weight: 219.24.
N-Nitroso Dabigatran
N-Nitroso Dabigatran is an impurity of Dabigatran, an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with atrial fibrillation. Molecular formula: C25H24N8O4. Mole weight: 500.52.
N-Nitroso Dabigatran Etexilate
N-Nitroso Dabigatran Etexilate is an impurity of Dabigatran, an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with atrial fibrillation. Synonyms: ethyl 3- (2- ( ( (4- (N- ( (hexyloxy) carbonyl) carbamimidoyl) phenyl) (nitroso) amino) methyl) -1-methyl-N- (pyridin-2-yl) -1H-benzo[d]imidazole-5-carboxamido) propanoate. Grades: 98%. Molecular formula: C34H40N8O6. Mole weight: 656.74.
N-Nitroso Dabigatran Impurity 14
N-Nitroso Dabigatran Impurity 14 is an impurity of Dabigatran, an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with atrial fibrillation. Synonyms: ethyl 3-(4-(methyl(nitroso)amino)-3-nitro-N-(pyridin-2-yl)benzamido)propanoate. Molecular formula: C18H19N5O6. Mole weight: 401.38.
N-Nitroso Dabigatran Impurity 33
N-Nitroso Dabigatran Impurity 33 is an impurity of Dabigatran, an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with atrial fibrillation. Synonyms: N-(4-cyanophenyl)-N-nitrosoglycine. Molecular formula: C9H7N3O3. Mole weight: 205.17.
N-Nitroso Dabigatran Impurity 65
N-Nitroso Dabigatran Impurity 65 is an impurity of Dabigatran, an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with atrial fibrillation. Synonyms: ethyl 3-(2-(((4-cyanophenyl)(nitroso)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate. Molecular formula: C27H25N7O4. Mole weight: 511.54.
N-Nitroso Dabigatran Impurity 73 Trifluoroacetate
N-Nitroso Dabigatran Impurity 73 Trifluoroacetate is an impurity of Dabigatran, an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with atrial fibrillation. Synonyms: ethyl 3- (2- ( ( (4-carbamimidoylphenyl) (nitroso)amino)methyl)-1-methyl-N- (pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate, 2,2,2-trifluoroacetic acid (1:1). Molecular formula: C29H29N8O6F3. Mole weight: 642.59.
N-Nitroso Dabigatran Impurity 75
N-Nitroso Dabigatran Impurity 75 is an impurity of Dabigatran, an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with atrial fibrillation. Molecular formula: C26H32N6O5. Mole weight: 508.58.
N-Nitroso Dabigatran Impurity 8
N-Nitroso Dabigatran Impurity 8 is an impurity of Dabigatran, an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with atrial fibrillation. Synonyms: ethyl 3- (2- ( ( (4- ( ( (hexyloxy)carbonyl)carbamoyl)phenyl) (nitroso)amino) methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate. Molecular formula: C34H39N7O7. Mole weight: 657.73.
N-Nitroso Dabigatran Impurity 82
N-Nitroso Dabigatran Impurity 82 is an impurity of Dabigatran, an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with atrial fibrillation. Synonyms: ethyl 3- (2- ( ( (4-carbamoylphenyl) (nitroso)amino)methyl)-1-methyl-N- (pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate. Molecular formula: C27H27N7O5. Mole weight: 529.56.
N-Nitroso Dabigatran Impurity 83
N-Nitroso Dabigatran Impurity 83 is an impurity of Dabigatran, an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with atrial fibrillation. Synonyms: ethyl 3-(nitroso(pyridin-2-yl)amino)propanoate. Molecular formula: C10H13N3O3. Mole weight: 223.23.
N-Nitroso Dabigatran Impurity 84
N-Nitroso Dabigatran Impurity 84 is an impurity of Dabigatran, an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with atrial fibrillation. Synonyms: Ethyl 3- (2- ( ( (4- (ethoxy (imino)methyl)phenyl) (nitroso)amino)methyl)-1-methyl-N- (pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate. Molecular formula: C29H31N7O5. Mole weight: 557.61.
N-Nitroso Dabigatran Impurity 89
N-Nitroso Dabigatran Impurity 89 is an impurity of Dabigatran, an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with atrial fibrillation. Synonyms: Ethyl 3-(3-amino-4-(methyl(nitroso)amino)-N-(pyridin-2-yl)benzamido)propanoate. Molecular formula: C18H21N5O4. Mole weight: 371.4.
N-Nitroso Desloratadine
N-Nitroso Desloratadine is one of loratadine intermediates. Loratadine is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Synonyms: 8-Chloro-6,11-dihydro-11-(1-nitroso-4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine; 5H-Benzo[5,6]cyclohepta[1,2-b]pyridine, 8-chloro-6,11-dihydro-11-(1-nitroso-4-piperidinylidene)-; 8-Chloro-11-(1-nitroso-4-piperidinylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine. Grades: 98%. CAS No. 1246819-22-6. Molecular formula: C19H18ClN3O. Mole weight: 339.82.
N-Nitroso Iminostilbene
N-Nitroso Iminostilbene is a metabolite of Carbamazepine, which is used in treatment of pain associated with trigeminal neuralgia. Synonyms: 5-Nitroso-5H-dibenz[b,?f]?azepine; N-Nitroso-5H-dibenz(b,f)azepine; 5H-Dibenz(b,f)azepine, 5-nitroso-; N-Nitrosodibenzazepine; N-Nitrosoiminostilbene. CAS No. 38652-29-8. Molecular formula: C14H10N2O. Mole weight: 222.24.
N-Nitroso N-Methoxycarbonyl Dabigatran Ethyl Ester is an impurity of Dabigatran, an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with atrial fibrillation. Molecular formula: C29H30N8O6. Mole weight: 586.61.
N'-Nitrosonornicotine N-β-D-Glucuronide (Mixture Of Diastereomers) X Hydrate
. Uses: A metabolite of n'-nitrosonornicotine. Synonyms: Pyridinium, 1-β-D-glucopyranuronosyl-3-(1-nitroso-2-pyrrolidinyl)-, inner salt, stereoisomer. CAS No. 350508-25-7. Molecular formula: C15H19N3O7. Mole weight: 353.33.
N-Nitroso Palbociclib HCl
N-Nitroso Palbociclib HCl is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: N4-Nitroso Piperazine HCl; 6-acetyl-8-cyclopentyl-5-methyl-2-((5-(4-nitrosopiperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one, hydrochloride (1:1). Molecular formula: C24H29N8O3Cl. Mole weight: 476.54.
N-Nitroso Palbociclib Impurity 11
N-Nitroso Palbociclib Impurity 11 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C33H44N8O5. Mole weight: 632.77.
N-Nitroso Palbociclib Impurity 35
N-Nitroso Palbociclib Impurity 35 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. CAS No. 2089333-12-8. Molecular formula: C9H11N5O3. Mole weight: 237.22.
N-Nitroso Palbociclib Impurity 43
N-Nitroso Palbociclib Impurity 43 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C27H33BrN8O4. Mole weight: 613.52.
N-Nitroso Palbociclib Impurity 53
N-Nitroso Palbociclib Impurity 53 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C9H10BrClN4O. Mole weight: 305.56.
N-Nitroso Palbociclib Impurity 84
N-Nitroso Palbociclib Impurity 84 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C12H13ClN4O2. Mole weight: 280.71.
(N-O) acyl isomer of Octreotide
(N-O) acyl isomer of Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-(2S,3R)-3-aminobutane-1,2-diol (Disulfide Bridge between Cys2-Cys7); D-phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cystyl-(2S,3R)-3-aminobutane-1,2-diol (Disulfide Bridge between Cys2-Cys7). Molecular formula: C49H66N10O10S2. Mole weight: 1019.25.
N,O-Dimethyl-Naltrexone Bromide
N,O-Dimethyl-Naltrexone Bromide is a derivative of Naltrexone, which is used to treat alcohol dependence and prevent relapse of opioid dependence. Synonyms: 3-(O)-Methylnaltrexone methobromide; (3R,4R,4aS,7aR,12bS)-3-(Cyclopropylmethyl)-4a-hydroxy-9-methoxy-3-methyl-7-oxo-2,3,4,4a,5,6,7,7a-octahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-3-ium Bromide. Grades: ≥95%. CAS No. 1005410-37-6. Molecular formula: C22H28BrNO4. Mole weight: 450.36.
Nogo-66 (1-40)
Nogo-66 (1-40), a peptide fragment corresponding to residues 1-40 of Nogo-66, acts as a competitive antagonist at the Nogo-66 receptor (NgR), which blocks Nogo-66 or CNS myelin inhibition of axonal outgrowth in vitro, demonstrating that NgR mediates a significant portion of axonal outgrowth inhibition by myelin. Synonyms: NEP1-40; Nogo Extracellular Peptide, 1-40. Grades: >95%. CAS No. 475221-20-6. Molecular formula: C206H324N56O65. Mole weight: 4625.16.
Nolatrexed dihydrochloride
Nolatrexed, also known as AG337, is a thymidylate synthase inhibitor with potential anticancer activity. A phase II study of nolatrexed in 2007 in advanced HCC patients demonstrated minimal activity and significant stomatitis. Synonyms: AG 337; Thymitaq; 2-Amino-6-methyl-5-(4-pyridinylthio)-4(1H)-quinazolinone Hydrochloride; 2-amino-6-methyl-5-(pyridin-4-ylsulfanyl)-1,4-dihydroquinazolin-4-one dihydrochloride; 3,4-Dihydro-2-amino-6-methyl-4-oxo-5-(4-pyridylthio)quinazoline dihydrochloride. Grades: 98%. CAS No. 152946-68-4. Molecular formula: C14H14Cl2N4OS. Mole weight: 357.25.
Noopept
Noopept is a nootropic and neuroprotective drug that normalizes the balance of the pro- and antioxidant systems. Noopept modulates a variety of physiological functions including cognition and anxiety. Noopept significantly weakens streptozotocin-Induced diabetes in rats. Synonyms: GVS-111; GVS111; GVS 111; SGS-111; SGS 111; SGS111. Grades: >98%. CAS No. 157115-85-0. Molecular formula: C17H22N2O4. Mole weight: 318.37.
Noradrenalone 3-sulfate is an intermediate in the synthesis of Norepinephrine, which is widely used as an injectable drug for the treatment of critically low blood pressure. Synonyms: 2-Amino-1-[4-hydroxy-3-(sulfooxy)phenyl]ethanone; [5-(2-Aminoacetyl)-2-hydroxyphenyl]oxidanesulfonic acid; 5-Glycyl-2-hydroxyphenyl hydrogen sulfate; Ethanone, 2-amino-1-[4-hydroxy-3-(sulfooxy)phenyl]-. CAS No. 80098-03-9. Molecular formula: C8H9NO6S. Mole weight: 247.22.
Noradrenalone Hydrochloride
An impurity of Norepinephrine. Norepinephrine, also known as noradrenaline, is a marker for catecholamine-secreting tumors such as pheochromocytoma, paraganglioma, and neuroblastoma. Synonyms: 2-Amino-1-(3,4-dihydroxyphenyl)ethan-1-one HCl; 2-Amino-1-(3,4-dihydroxyphenyl)ethanone hydrochloride. Grades: > 95%. CAS No. 5090-29-9. Molecular formula: C8H9NO3.HCl. Mole weight: 203.62.
Noradrenochrome
Noradrenochrome is an impurity of Noradrenaline, which is widely used as an injectable drug for the treatment of critically low blood pressure. Synonyms: 1H-Indole-5,6-dione, 2,3-dihydro-3-hydroxy-; Cyclized norepinephrine ortho-quinone; Norepinephrine Impurity 21; 3-Hydroxy-5,6-indolinedione. Grades: ≥95%. CAS No. 490-89-1. Molecular formula: C8H7NO3. Mole weight: 165.15.