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Omega-1-Hydroxy Eperisone
A metabolite of Eperisone. Eperisone relaxes both skeletal muscles and vascular smooth muscles. Synonyms: 1-(4-(1-hydroxyethyl)phenyl)-2-methyl-3-(piperidin-1-yl)propan-1-one. Grades: > 95%. Molecular formula: C17H25NO2. Mole weight: 275.39.
Omega-Hydroxy Eperisone
A metabolite of Eperisone. Eperisone relaxes both skeletal muscles and vascular smooth muscles. Synonyms: 1-(4-(2-hydroxyethyl)phenyl)-2-methyl-3-(piperidin-1-yl)propan-1-one. Grades: > 95%. Molecular formula: C17H25NO2. Mole weight: 275.39.
Omiganan Pentahydrochloride
Omiganan is a synthetic cationic antimicrobial peptide with wide-spectrum activity against both gram-positive and gram-negative bacteria. Uses: Anti-infective agents. Synonyms: MBI 226; MBI-226; MBI226; Omiganan HCl. Grades: 98%. CAS No. 269062-93-3. Molecular formula: C90H132Cl5N27O12. Mole weight: 1961.4.
Onalespib
Onalespib, also known as AT13387, is a synthetic, orally bioavailable, small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity. AT13387 selectively binds to Hsp90, thereby inhibiting its chaperone function and promoting the degradation of oncogenic signaling proteins involved in tumor cell proliferation and survival. Synonyms: AT13387; AT 13387; AT-13387. Grades: >98%. CAS No. 912999-49-6. Molecular formula: C24H31N3O3. Mole weight: 409.52.
Oncrasin-1
Oncrasin-1 is a potent and effective anticancer inhibitor that kills various human lung cancer cells with K-Ras mutations at low or submicromolar concentrations. It also led to abnormal aggregation of PKCΙ in nucleus of sensitive cells but not in resistant cells. Synonyms: 1-[(4-chlorophenyl)methyl]indole-3-carbaldehyde. Grades: 98 %. CAS No. 75629-57-1. Molecular formula: C16H12ClNO. Mole weight: 269.73.
o-Nicotine
o-Nicotine is a Nicotine analog, which is a potent parasympathomimetic stimulant. Uses: Has high affinity for nicotinic receptor, and its ability to elicit neurotransmitter secretions make it a good candidate for treating cholinergic neurodegenerative diseases. Synonyms: 2-(1-Methyl-2-pyrrolidinyl)pyridine; ortho-Nicotine; Pyridine, 2-(1-methyl-2-pyrrolidinyl)-; Pyridine, 2-(1-methyl-2-pyrrolidinyl)-, (±)-; α-Nicotine; α-Pyridyl-α-methylpyrrolidine. Grades: 96%. CAS No. 23950-04-1. Molecular formula: C10H14N2. Mole weight: 162.23.
ONO-4059
ONO-4059, a BTK inhibitor, has been found to have potential effect against sorts of malignancies by influencing the B-cell development. It is currently under Phase II trail to study its effect against Chronic lymphocytic leukaemia. IC50: 2.2 nM. Synonyms: (R)-6-amino-9-(1-(but-2-ynoyl)pyrrolidin-3-yl)-7-(4-phenoxyphenyl)-7,9-dihydro-8H-purin-8-one; ONO-4059; ONO4059; ONO 4059; ONO-4059; GS 4059; GS-4059; GS4059; ONO-WG-307; Tirabrutinib. Grades: 98%. CAS No. 1351636-18-4. Molecular formula: C25H22N6O3. Mole weight: 454.48.
ONO-4059 (hydrochloride)
ONO-4059 (hydrochloride) is the hydrochloride salt form of Tirabrutinib. ONO-4059 is a highly selective, orally bioavailable BTK inhibitor (IC50= 2.2 nM) and demonstrated therapeutic efficacy in a mouse arthritis model. Synonyms: (R)-6-amino-9-(1-(but-2-ynoyl)pyrrolidin-3-yl)-7-(4-phenoxyphenyl)-7,9-dihydro-8H-purin-8-one hydrochloride; ONO-4059 HCl; ONO4059; ONO 4059; ONO-4059; GS 4059; GS-4059; GS4059; ONO-WG-307; Tirabrutinib. CAS No. 1439901-97-9. Molecular formula: C25H23ClN6O3. Mole weight: 490.95.
ONO-7475
ONO-7475 is an Axl/Mer inhibitor that has been shown to inhibit the phosphorylation of AXL and Mer, and to suppress the growth of acute myeloid leukemia with FLT3 mutations (26, 27) and solid tumors. Synonyms: ONO 7475; ONO7475. Grades: >98%. CAS No. 1646839-59-9. Molecular formula: C32H26N4O6. Mole weight: 562.6.
ONO-AE3-208
ONO-AE3-208 is an EP4 antagonist (Ki values are 1.3, 30, 790 and 2400 nM for EP4, EP3, FP and TP receptors respectively), which less potently affects EP3, FP, and TP receptors. Uses: An ep4 antagonist. Synonyms: ONO-AE3-208; ONO-AE-3-208; ONO-AE 3-208; AE 3-208; AE-3-208; AE3-208; ONO AE3 208 4-Cyano-2-[[2-(4-fluoro-1-naphthalenyl)-1-oxopropyl]amino]benzenebutanoic acid; 4-[4-cyano-2-[2-(4-fluoronaphthalen-1-yl)propanoylamino]phenyl]butanoic acid. Grades: ≥98%. CAS No. 402473-54-5. Molecular formula: C24H21FN2O3. Mole weight: 404.43.
(+)-O,O'-Dibenzoyl-D-tartaric Acid Monohydrate
(+)-Dibenzoyl-D-Tartaric Acid Monohydrate can be used to treat type 2 diabetes mellitus. Synonyms: (2S,3S)-2,3-dibenzoyloxybutanedioic acid;hydrate; (2S,3S)-2,3-dibenzoyloxybutanedioic acid;hydrate. Grades: > 95 %. CAS No. 80822-15-7. Molecular formula: C18H16O9. Mole weight: 376.31.
Orantinib
Orantinib is a multiple receptor tyrosine kinase inhibitor with IC50s of 2.1 μM, 8 nM and 1.2 μM for VEGF-R1, PDGF-Rβ and FGF-R1, respectively. It has greatest potency against PDGFR autophosphorylation. Synonyms: 3-(2,4-dimethyl-5-((2-oxoindolin-3-ylidene)methyl)-1H-pyrrol-3-yl)propanoic Acid; 3-[2,4-Dimethyl-5-[(2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propionic Acid; 3-[4-(2-Carboxyethyl)-3,5-dimethylpyrrol-2-methylidenyl]-2-indolinone; 5-[(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic acid; NSC 702827; SU 6668; TSU-68. Grades: ≥98%. CAS No. 252916-29-3. Molecular formula: C18H18N2O3. Mole weight: 310.35.
Orexin A (human, rat, mouse)
An orexin receptors agonist. It can stimulate feeding following central administration. Grades: 95%. CAS No. 205640-90-0. Molecular formula: C152H243N47O44S4. Mole weight: 3561.12.
ORG-27569
Org 27569 is an allosteric modulator of cannabinoid CB1 receptor, induces a CB1 receptor state that is characterized by enhanced agonist affinity and decreased inverse agonist affinity. Synonyms: ORG-27569; ORG-27569; ORG-27569. Grades: 0.98. CAS No. 868273-06-7. Molecular formula: C24H28ClN3O. Mole weight: 409.95.
ORM-15341
ORM-15341, an androgen receptor antagonist, have potential effect against prostate cancer and is commonly found as an active main metabolite of ODM-201. IC50 = 38 nM. Synonyms: CS-5191; ORM 15341; CS 5191; ORM15341; CS5191. Grades: 98%. CAS No. 1297537-33-7. Molecular formula: C19H17ClN6O2. Mole weight: 396.83.
Ornipressin Acetate
Ornipressin is a vasoconstrictor, haemostatic and renal agent. Ornipressin plus dopamine can be a useful therapeutic option in patients with HRS type 1, especially as bridge to liver transplantation. Uses: Hemostatics. Synonyms: c[Cys-Tyr-Phe-Gln-Asn-Cys]-Pro-Orn-Gly-NH2. Grades: 98%. CAS No. 3397-23-7. Molecular formula: C45H63N13O12S2. Mole weight: 1042.19.
ortho-Mirabegron
ortho-Mirabegron is an isomer of Mirabegron, a potent bladder relaxant and reagent for diabetes remedy. Synonyms: 2-Amino-N-[2-[2-[[(2R)?-2-hydroxy-2-phenylethyl]?amino]?ethyl]?phenyl]?-4-thiazoleacetamide. CAS No. 1684452-80-9. Molecular formula: C21H24N4O2S. Mole weight: 396.51.
ORY-1001 dihydrochloride
ORY-1001 is a lysine specific demethylase 1 inhibitor under the development of Oryzon with IC50 value < 20nM. It selectively inhibits related FAD dependent aminoxidases (MAO-A/B, IL4I1, KDM1B> 100uM, SMOX 7uM). ORY-1001 can induce apoptosis in THP-1 and inhibit proliferation and colony formation of MV(4;11) (MLL-AF4) cells (EC50 <1nM). In THP-1 (MLL-AF9) cells, ORY-1001 results in a time-dose dependent me2H3K4 accumulation at KDM1A target genes and concomitant induction of differentiation markers. Synonyms: RG-6016; RG 6016; RG6016; ORY-1001 2HCl; ORY 1001 2HCl; ORY1001 2HCl; (1R,4R)-N1-((1R,2S)-2-phenylcyclopropyl)cyclohexane-1,4-diamine dihydrochloride. Grades:>98%. CAS No. 1431326-61-2. Molecular formula: C15H24Cl2N2. Mole weight: 303.27.
Oseltamivir 5-Desamino 5-(2-Formyl 5-Hydroxymethylpyrrol-1-yl) is derived from Oseltamivir Phosphate, which can be used in COVID19-related research. Synonyms: ethyl (3R,4R,5S)-4-acetamido-5-(2-formyl-5-(hydroxymethyl)-1H-pyrrol-1-yl)-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylate; (3R,4R,5S)-Ethyl 4-acetamido-5-(2-formyl-5-(hydroxymethyl)-1H-pyrrol-1-yl)-3-(pentan-3-yloxy)cyclohex-1-enecarboxylate; 1-Cyclohexene-1-carboxylic acid, 4-(acetylamino)-3-(1-ethylpropoxy)-5-[2-formyl-5-(hydroxymethyl)-1H-pyrrol-1-yl]-, ethyl ester, (4R,5S)-. Molecular formula: C22H32N2O6. Mole weight: 420.50.
Oseltamivir-acetate
Oseltamivir-acetate is an impurity of Oseltamivir, which is an acetamido cyclohexene that is a structural homolog of sialic acid and inhibits neuraminidase. Synonyms: (3R,4R,5S)-ethyl 4,5-diacetamido-3-(pentan-3-yloxy)cyclohex-1-enecarboxylate. Grades: ≥98% (HPLC). CAS No. 1191921-01-3. Molecular formula: C18H30N2O5. Mole weight: 354.45.
Oseltamivir Acid Hydrochloride
Oseltamivir Acid Hydrochloride is a metabolite of Oseltamivir, which can be used in COVID19-related research. Synonyms: Oseltamivir EP Impurity C HCl; (3R,4R,5S)-4-Acetamido-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid hydrochloride (1:1); Oseltamivir carboxylate hydrochloride; 1-Cyclohexene-1-carboxylic acid, 4-(acetylamino)-5-amino-3-(1-ethylpropoxy)-, (3R,4R,5S)-, hydrochloride (1:1). Grades: ≥95%. CAS No. 1415963-60-8. Molecular formula: C14H25ClN2O4. Mole weight: 320.81.
Oseltamivir Acid Isopropyl Ester Phosphoric Acid
Oseltamivir Acid Isopropyl Ester Phosphoric Acid is a derivative of Oseltamivir Phosphate, which can be used in COVID19-related research. Synonyms: (3R,4R,5S)-Isopropyl 4-acetamido-5-amino-3-(pentan-3-yloxy)cyclohex-1-enecarboxylate Phosphoric Acid; Oseltamivir Impurity pound C Phosphoric Acid. Molecular formula: C17H33N2O8P. Mole weight: 424.42.
Oseltamivir Biotin conjugate 1
Synonyms: Tamiphosphor, biotin conjugate. CAS No. 1612755-43-7. Molecular formula: (C2H4O)nC35H63N6O9PS.
Oseltamivir Carboxylic Acid
Cas No. 187227-45-8.
Oseltamivir Citric Acid Adduct tert-Butyl Ester
Oseltamivir Citric Acid Adduct tert-Butyl Ester is an intermediate of Oseltamivir, which can be used in COVID19-related research. Synonyms: 5-{[(1S,5R,6R)-6-Acetamido-3-(ethoxycarbonyl)-5-(3-pentanyloxy)-3-cyclohexen-1-yl]amino}-3-hydroxy-3-{[(2-methyl-2-propanyl)oxy]carbonyl}-5-oxopentanoic acid; Butanedioic acid, 2-[2-[[(1S,5R,6R)-6-(acetylamino)-3-(ethoxycarbonyl)-5-(1-ethylpropoxy)-3-cyclohexen-1-yl]amino]-2-oxoethyl]-2-hydroxy-, 1-(1,1-dimethylethyl) ester. Molecular formula: C26H42N2O10. Mole weight: 542.62.
Oseltamivir impurity F
Cas No. 1052063-37-2.
Oseltamivir Impurity G
Cas No. 956267-10-0.
Oseltamivir Phosphate
Oseltamivir phosphate (Tamiflu) is a competitive neuraminidase inhibitor. The prodrug oseltamivir phosphate (Tamiflu) is itself not virally effective. Uses: Antiviral agents. Synonyms: (3R,4R,5S)-4-(Acetylamino)-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylic Acid Ethyl Ester Phosphate; Oseltamir Phosphate; Ro 64-0796/002; Tamiflu. Grades: >98%. CAS No. 204255-11-8. Molecular formula: C16H31N2O8P. Mole weight: 410.40.
OSI-930
OSI-930 is a selective thiophene-derived tyrosine kinase inhibitor with potential antineoplastic activity. Tyrosine kinase inhibitor OSI-930 inhibits stem cell factor receptor (c-Kit) and the vascular endothelial growth factor receptor 2 (VEGFR2), which may result in the inhibition of both tumor cell proliferation and tumor angiogenesis. Both c-Kit and VEGFR2 are overexpressed in a variety of cancers. Synonyms: OSI 930; OSI930. Grades: >98%. CAS No. 728033-96-3. Molecular formula: C22H16F3N3O2S. Mole weight: 443.444.
OSU 03012
OSU 03012 is an orally available, targeted anti-cancer agent that has been shown in pre-clinical studies to inhibit PDK-1, a protein in the PI3K/Akt pathway that is involved in the growth and proliferation of cells, including cancer cells. OSU 03012 may also cause cell death through the induction of stress in the endoplasmic reticulum. Synonyms: AR-12; OSU-03012; 2-amino-N-[4-[5-phenanthren-2-yl-3-(trifluoromethyl)pyrazol-1-yl]phenyl]acetamide. Grades: >98%. CAS No. 742112-33-0. Molecular formula: C26H19F3N4O. Mole weight: 460.46.
O-Triacetyl 12-Acetloxy Deshydroxy Digoxin
O-Triacetyl 12-Acetloxy Deshydroxy Digoxin is an intermediate in the synthesis of Digoxigenin Tetradigitoxoside, which is an impurity of Digoxin. Synonyms: (3β,5β,12β)-12-Acetoxy-3-{[3-O-acetyl-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1->4)-3-O-acetyl-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1->4)-3-O-acetyl-2,6-dideoxy-β-D-ribo-hexopyranosyl]oxy}-14-hydroxycard-20(22)-enolide; Card-20(22)-enolide, 3-[[O-3-O-acetyl-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1->4)-O-3-O-acetyl-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1->4)-3-O-acetyl-2,6-dideoxy-β-D-ribo-hexopyranosyl]oxy]-12-(acetyloxy)-14-hydroxy-, (3β,5β,12β)-. Molecular formula: C49H72O18. Mole weight: 949.08.
OTS514 hydrochloride
The hydrochloride of OTS514. OTS514 is a potent TOPK (T-LAK cell-originated protein kinase) inhibitor (IC50 = 2.6 nM), with an inhibitory effect on small cell lung cancer (SCLC). It acts through suppressing growth of SCLC cell lines and inducing their apoptotic cell death. Synonyms: OTS 514 hydrochloride; OTS-514 hydrochloride; OTS514 HCl. Grades: 99.42 %. CAS No. 2319647-76-0. Molecular formula: C21H20N2O2S.HCl. Mole weight: 400.92.
OTS-964 hydrochloride
OTS-964, a thienoquinolin derivative, is a TOPK inhibitor and prabably be useful in studying anticancer agent as an analogue of OTS-514. It is still under preclinical trial. IC50: 28 nM. Synonyms: OTS964; OTS 964; OTS-964. Grades: 98%. CAS No. 1338545-07-5. Molecular formula: C23H25ClN2O2S. Mole weight: 428.97.
OTSSP167 hydrochloride
OTSSP167 is a potent inhibitor of Maternal embryonic leucine zipper kinase (MELK) which regulates neural stem cell selfrenewal through control of the cell cycle. Synonyms: 4-[7-acetyl-8-[[4-[ (dimethylamino) methyl]cyclohexyl]amino]-1H-1, 5-naphthyridin-2-ylidene]-2, 6-dichlorocyclohexa-2, 5-dien-1-one hydrochloride; OTSSP167 (hydrochloride); UNII-65P731R507; 65P731R507; OTSSP167 HCl; OTS-167 monohydrochloride; HY-15512A; AKOS025117447. CAS No. 1431698-10-0. Molecular formula: C25H29Cl3N4O2. Mole weight: 523.9.
OTX015
OTX015 is a potent BET bromodomian inhibitor, which targets the BET bromodomain proteins 2, 3, and 4 (BRD). BRDs 2, 3, and 4 are considered potential cancer targets because of their pivotal role in regulating the transcription of growth-promoting genes and cell cycle regulators. Synonyms: OTX-015; OTX 015; MK-8628; MK 8628; MK8628; Birabresib; (S)-2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-N-(4-hydroxyphenyl)acetamide. Grades: >98%. CAS No. 202590-98-5. Molecular formula: C25H22ClN5O2S. Mole weight: 492.00.
Thioxacillin is a derivative (impurity) of Oxacillin which is used as an antibiotic related to Penicillin. Synonyms: 3,3-Dimethyl-6-(5-methyl-3-phenyl-4-isoxazolecarboxamido)-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carbothioic Acid. Grades: > 95%. CAS No. 5053-35-0. Molecular formula: C19H19N3O4S2. Mole weight: 417.5.
Oxacillin Penillic Acid Disodium Salt (Mixture of Diastereomers)
Oxacillin Penillic Acid Disodium Salt is a derivative of Oxacillin, which is used as an antibiotic related to Penicillin. Synonyms: 2,3,7,7a-Tetrahydro-2,2-dimethyl-5-(5-methyl-3-phenyl-4-isoxazolyl)-Imidazo[5,1-b]thiazole-3,7-dicarboxylic Acid Disodium Salt; Disodium 2,2-dimethyl-5-(5-methyl-3-phenyl-1,2-oxazol-4-yl)-2,3,7,7a-tetrahydroimidazo[5,1-b][1,3]thiazole-3,7-dicarboxylate; Imidazo[5,1-b]thiazole-3,7-dicarboxylic acid, 2,3,7,7a-tetrahydro-2,2-dimethyl-5-(5-methyl-3-phenyl-4-isoxazolyl)-, sodium salt (1:2). Grades: 80%. Molecular formula: C19H17N3Na2O5S. Mole weight: 445.40.
Oxfendazole
Oxfendazole is the sulfoxide form of fenbendazole which is a broad spectrum benzimidazole anthelmintic. It can be used to control nematode disease and tapeworm disease in livestock. Uses: Antinematodal agents. Synonyms: RS-8858; RS 8858; RS8858. Grades: >98%. CAS No. 53716-50-0. Molecular formula: C15H13N3O3S. Mole weight: 315.35.
Oxiconazole Nitrate
Oxiconazole nitrate is a broad-spectrum imidazole antifungal agent. It is used to treat skin infections such as jock itch, athlete's foot and ringworm. It is also used to treat the skin rash known as tinea versicolor caused by systemic yeast overgrowth. It inhibits a broad spectrum of pathogenic yeasts and molds, including C. neoformans, A. fumigatus, C. albicans, and T. mentagrophytes by inhibiting ergosterol biosynthesis. Uses: Antifungal agents. Synonyms: Ro 13-8996; (Z)-1-[2-(2,4-dichlorophenyl)-2-[[(2,4-dichlorophenyl)oxy]imino]ethyl]-1H-imidazole mononitrate; Myfungar; Oceral; Oxistat; (1Z)-N-[(2,4-dichlorobenzyl)oxy]-1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethanimine nitrate; Ethanone, 1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)-, O-[(2,4-dichlorophenyl)methyl]oxime, (1Z)-, nitrate (1:1). Grades: 98%. CAS No. 64211-46-7. Molecular formula: C18H13Cl4N3O. Mole weight: 492.14.
Oxiglutatione
Cas No. 27025-41-8.
Oxoprolintane
Oxoprolintane is a metabolite of Prolintane, which is a stimulant and norepinephrine-dopamine reuptake inhibitor. Synonyms: 1-[1-(Phenylmethyl)butyl]-2-pyrrolidinone; (±)-1-(α-Propylphenethyl)pyrrolidin-2-one; 1-(α-Propylphenethyl)pyrrolidin-2-one. Grades: ≥95%. CAS No. 35259-27-9. Molecular formula: C15H21NO. Mole weight: 231.33.
Oxybuprocaine hydrochloride
Oxybuprocaine hydrochloride reversibly blocks sodium channels, which can be potentially used in ophthalmology and otolaryngology as a local anesthetic. Uses: Local anesthetic. Synonyms: Benoxinate hydrochloride; 2-(Diethylamino)ethyl 4-amino-3-butoxybenzoate hydrochloride; Oxybuprocaine HCl. Grades: 98%. CAS No. 5987-82-6. Molecular formula: C17H29ClN2O3. Mole weight: 344.88.
Oxybutynin HCl
Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties. Uses: Muscarinic antagonists. Synonyms: Oxybutynin Hydrochloride; Oxybutynin HCl. Grades: >98%. CAS No. 1508-65-2. Molecular formula: C22H31NO3.HCl. Mole weight: 393.95.
Oxybutynin N-Oxide
Oxybutynin N-Oxide is a metabolite of oxybutynin, which is an inhibitor of proliferation and supresses gene expression in bladder smooth muscle cells. Uses: A metabolite of oxybutynin. Synonyms: α-Cyclohexyl-α-hydroxybenzeneacetic Acid 4-(Diethyloxidoamino)-2-butyn-1-yl Ester; Benzeneacetic acid, α-cyclohexyl-α-hydroxy-, 4-(diethyloxidoamino)-2-butyn-1-yl ester; 4-(Diethyloxidoamino)-2-butyn-1-yl α-cyclohexyl-α-hydroxybenzeneacetate; Benzeneacetic acid, α-cyclohexyl-α-hydroxy-, 4-(diethylamino)-2-butynyl ester, N-oxide; Benzeneacetic acid, α-cyclohexyl-α-hydroxy-, 4-(diethyloxidoamino)-2-butynyl ester. Grades: 98%. CAS No. 80976-68-7. Molecular formula: C22H31NO4. Mole weight: 373.48.
Oxytetracycline EP Impurity C
Oxytetracycline EP Impurity C is an impurity of Oxytetracycline, which is a broad-spectrum tetracycline antibiotic used for the treatment of various infectious diseases, like anthrax, Chlamydia, cholera, typhus, relapsing fever, malaria, plaque, syphilis, respiratory infection, streptococcal infection, and acne. Synonyms: 2-Acetyl-2-decarbamoyloxytetracycline; Oxytetracycline Impurity C; Terramycin-X; 1,11(4H,5H)-Naphthacenedione, 2-acetyl-4-(dimethylamino)-4a,5a,6,12a-tetrahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-, (4S,4aR,5S,5aR,6S,12aS)-; (4S,4aR,5S,5aR,6S,12aS)-2-Acetyl-4-(dimethylamino)-4a,5a,6,12a-tetrahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11(4H,5H)-naphthacenedione; 1,11(4H,5H)-Naphthacenedione, 2-acetyl-4-(dimethylamino)-4a,5a,6,12a-tetrahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-, [4S-(4α, 4aα, 5α, 5aα, 6β, 12aα)]-; Oxytetracycline, 2-acetyl-2-de(aminocarbonyl)-; 2-Acetyl-2-de(carbamoyloxy)tetracycline; 2-Acetyl-2-de(carboxamidooxy)tetracycline; Oxytetracycline Dihydrate EP Impurity C; Oxytetracycline Hydrochloride EP Impurity C. Grades: ≥95%. CAS No. 7647-65-6. Molecular formula: C23H25NO9. Mole weight: 459.45.
Ozagrel Methyl Ester
Ozagrel Methyl Ester is an impurity of Ozagrel, an antiplatelet drug that acts as a thromboxane A2 synthesis inhibitor. Synonyms: methyl (E)-3-(4-((1H-imidazol-1-yl)methyl)phenyl)acrylate; (2E)-3-[4-(1H-imidazol-1-ylmethyl)phenyl]-methyl Ester 2-Propenoic Acid. CAS No. 956932-46-0. Molecular formula: C14H14N2O2. Mole weight: 242.27.
Ozanimod
Ozanimod, also known as RPC1063, is a selective oral S1P Receptor 1 modulator. Synonyms: RPC1063; RPC-1063; RPC 1063; Ozanimod; 5-[3-[(1S)-1-(2-hydroxyethylamino)-2,3-dihydro-1H-inden-4-yl]-1,2,4-oxadiazol-5-yl]-2-propan-2-yloxybenzonitrile. CAS No. 1306760-87-1. Molecular formula: C23H24N4O3. Mole weight: 404.47.
P-(1,2-Dihydroxypropyl)phosphonic Acid
Cas No. 84954-80-3.
P-[(1R,2R)-1,2-Dihydroxypropyl]-phosphonic Acid Ammonium Salt
P-[(1R,2R)-1,2-Dihydroxypropyl]-phosphonic Acid Ammonium Salt is one of fosfomycin impurities. Fosfomycin is an antibiotic that exerts a broad spectrum of antibacterial activity. It was produced by certain Streptomyces species. Synonyms: 1160525-87-0; Diazanium; (1R,2R)-1-phosphonatopropane-1,2-diolP-[(1R,2R)-1,2-Dihydroxypropyl]-phosphonic Acid Ammonium Salt((1R,2R)-1,2-Dihydroxypropyl)phosphonate xammonium saltstarbld0003549. CAS No. 1160525-87-0. Molecular formula: C3H9O5P.xNH3. Mole weight: 156.07 (free base).
P-[(1R,2R)-1,2-Dihydroxypropyl]phosphonic Acid Bis(phenylmethyl) Ester is one of fosfomycin intermediates. Fosfomycin is an antibiotic that exerts a broad spectrum of antibacterial activity. It was produced by certain Streptomyces species. Synonyms: Phosphonic acid, P-[(1R,2R)-1,2-dihydroxypropyl]-, bis(phenylmethyl) ester; [(1R,2R)-1,2-Dihydroxypropyl]phosphonic Acid Bis(phenylmethyl) Ester; Dibenzyl ((1R,2R)-1,2-dihydroxypropyl)phosphonate; [(1R,2R)-1,2-Dihydroxypropyl]phosphonic acid dibenzyl ester. Molecular formula: C17H21O5P. Mole weight: 336.32.
P-[ (1R, 2R) -2-Hydroxy-1-[[ (4-methylphenyl) sulfonyl]oxy]propyl]phosphonic Acid Bis(phenylmethyl) Ester is one of fosfomycin impurities. Fosfomycin is an antibiotic that exerts a broad spectrum of antibacterial activity. It was produced by certain Streptomyces species. Synonyms: [ (1R, 2R) -2-Hydroxy-1-[[ (4-methylphenyl) sulfonyl]oxy]propyl]phosphonic Acid Bis(phenylmethyl) Ester. Molecular formula: C24H27O7PS. Mole weight: 490.50.
P-[2-Hydroxy-1-(phenylmethoxy)propyl]phosphonic Acid Dimethyl Ester is one of fosfomycin impurities. Fosfomycin is an antibiotic that exerts a broad spectrum of antibacterial activity. It was produced by certain Streptomyces species. Molecular formula: C12H19O5P. Mole weight: 274.25.
P7C3-A20
P7C3-A20, an analogue of P7C3, is a neuroprotective compound which inhibits mature neuronal cell death while also increasing the net magnitude of postnatal neurogenesis in models of neurodegeneration and acute injury. Synonyms: N-(3-(3,6-dibromo-9H-carbazol-9-yl)-2-fluoropropyl)-3-methoxyaniline; P7C-3A20; P7C3A20; P7C 3A20. CAS No. 1235481-90-9. Molecular formula: C22H19Br2FN2O. Mole weight: 506.21.
PA-824
PA-824, a bioreductive drug. PA-824 has potent in vitro activity against Mycobacterium tuberculosis. PA-824 was tested in vitro against a broad panel of multidrug-resistant clinical isolates and was found to be highly active against all isolates (MIC<1 microg/ml). PA-824 showed significant activity at 2, 10, and 50 microg/ml, similar to that of metronidazole, in a dose-dependent manner. Synonyms: PA824; PA-824; PA 824; Pretomanid. Grades:>98%. CAS No. 187235-37-6. Molecular formula: C14H12F3N3O5. Mole weight: 359.26.
PAB-Ertapenem Impurity
An impurity of Ertapenem. Ertapenem is a carbapenem antibiotic. Synonyms: (4R,5S,6S)-3-(((3R,5S)-1-(4-aminobenzyl)-5-((3-carboxyphenyl)carbamoyl)pyrrolidin-3-yl)thio)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid. Grades: > 95%. Molecular formula: C29H30N4O7S. Mole weight: 578.65.
Pabociclib Impurity B
An impurity of Palbociclib, a selective inhibitor of cyclin-dependent kinases CDK4 and CDK6. Palbociclib is developed for the treatment of ER-positive and HER2-negative breast cancer. Synonyms: tert-butyl 4-[6-[(6-acetyl-8-cyclopentyl-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]pyridin-3-yl]piperazine-1-carboxylate. Grades: >95%. CAS No. 1651214-74-2. Molecular formula: C29H37N7O4. Mole weight: 547.66.
Pabociclib Impurity B Hydrochloride
An impurity of Palbociclib, a selective inhibitor of cyclin-dependent kinases CDK4 and CDK6. Palbociclib is developed for the treatment of ER-positive and HER2-negative breast cancer. Synonyms: tert-butyl 4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate hydrochloride. CAS No. 1883672-48-7. Molecular formula: C29H38ClN7O4. Mole weight: 584.11.
PACAP (1-27), human, ovine, rat
Pituitary adenylate cyclase activating polypeptide (PACAP 1-27) is an endogenous neuropeptide showing considerable homology with vasoactive intestinal peptide (VIP). It is a potent PACAP receptor agonist. Synonyms: PACAP 1-27; Pituitary Adenylate Cyclase Activating Polypeptide1-27; H-His-Ser-Asp-Gly-Ile-Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-NH2; L-histidyl-L-seryl-L-alpha-aspartyl-glycyl-L-isoleucyl-L-phenylalanyl-L-threonyl-L-alpha-aspartyl-L-seryl-L-tyrosyl-L-seryl-L-arginyl-L-tyrosyl-L-arginyl-L-lysyl-L-glutaminyl-L-methionyl-L-alanyl-L-valyl-L-lysyl-L-lysyl-L-tyrosyl-L-leucyl-L-alanyl-L-alanyl-L-valyl-L-leucinamide. Grades: ≥98% by HPLC. CAS No. 127317-03-7. Molecular formula: C142H224N40O39S. Mole weight: 3147.60.
An activator of cAMP formation. It stimulates sympathetic neuronal NPY and catecholamine production. Synonyms: PACAP-38 (31-38), human, mouse, rat; PACAP (31-38); Tyr-Lys-Gln-Arg-Val-Lys-Asn-Lys-NH2; L-tyrosyl-L-lysyl-L-glutaminyl-L-arginyl-L-valyl-L-lysyl-L-asparagyl-L-lysinamide. Grades: ≥98%. CAS No. 138764-85-9. Molecular formula: C47H83N17O11. Mole weight: 1062.27.
Paclitaxel-8-hydro-bicyclo(3.3.0)octane
Paclitaxel-8-hydro-bicyclo(3.3.0)octane is an analogue of Paclitaxel, which is a chemotherapy medication used to treat a number of types of cancer. Synonyms: (1R, 2R, 4S, 5S, 7R, 10S, 11R, 12S, 13S, 15S, 16S)-2, 10-diacetyloxy-5, 13-dihydroxy-4, 16, 17, 17-tetramethyl-8-oxa-3-oxo-12-phenylcarbonyloxypentacyclo[11. 3. 1. 01, 11. 04, 11. 07, 10]heptadec-15-yl (2R,3S)-2-hydroxy-3-phenyl-3-(phenylcarbonylamino)propanoate; Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, 2a,8-bis(acetyloxy)-3-(benzoyloxy)dodecahydro-4,10-dihydroxy-7,9a,12,12-tetramethyl-9-oxo-3H-4,7a-methanocyclohept[3,3a]indeno[5,4-b]oxet-6-yl ester, [2aS-[2aα, 2bS*, 3α, 4α, 6α(αS*, βR*), 7β, 7aβ, 8β, 9aβ, 10β, 11aα]]-; Paclitaxel Photodegradant; Paclitaxel Photodegradant Impurity. Grades: 93%. CAS No. 146139-03-9. Molecular formula: C47H51NO14. Mole weight: 853.90.
Pagoclone
Pagoclone, an active (+)-enantiomer of the racemate RP 59037, is a ubtype selective partial agonist at GABAA receptor and used for the treatment of panic and anxiety disorders. Synonyms: CI-1043; IP-456; RP-62955; RP-59037; CI1043; IP456; RP62955; RP59037; Bextra. CAS No. 133737-32-3. Molecular formula: C23H22ClN3O2. Mole weight: 407.89.
Palbociclib HCl
Palbociclib, also known as PD0332991, is an orally available pyridopyrimidine-derived cyclin-dependent kinase (CDK) inhibitor with potential antineoplastic activity. PD-0332991 selectively inhibits cyclin-dependent kinases (particularly Cdk4/cyclin D1 kinase), which may inhibit retinoblastoma (Rb) protein phosphorylation; inhibition of Rb phosphorylation prevents Rb-positive tumor cells from entering the S phase of the cell cycle (arrest in the G1 phase), resulting in suppression of DNA replication and decreased tumor cell proliferation. PD 0332991 is a highly specific inhibitor of cyclin-dependent kinase 4 (Cdk4) (IC50=0.011 μmol/L) and Cdk6 (IC50=0.016 μmol/L), having no activity against a panel of 36 additional protein kinases. Synonyms: PD 0332991; PD 332991; PD0332991; PD-0332991; Palbociclib hydrochloride. Grades: >98%. CAS No. 827022-32-2. Molecular formula: C24H29N7O2.HCl. Mole weight: 483.99.
Palbociclib Impurity 002
An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Molecular formula: C14H21BrN4. Mole weight: 325.25.
Palbociclib Impurity 022
An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Synonyms: tert-Butyl 4-(2-nitropyridin-3-yl)piperazine-1-carboxylate; 1779124-68-3; tert-Butyl4-(2-nitropyridin-3-yl)piperazine-1-carboxylate; SCHEMBL17550837; CS-0448403; EN300-7455913. Grades: 95%. CAS No. 1779124-68-3. Molecular formula: C14H20N4O4. Mole weight: 308.33.
Palbociclib Impurity 025
An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Synonyms: N-Formyl Palbociclib; Palbociclib Impurity F; Palbociclib N-Aldehyde; Palbociclib N-Formyl Impurity. Grades: 95%. CAS No. 2174002-16-3. Molecular formula: C25H29N7O3. Mole weight: 475.54.
Palbociclib Impurity 026
An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Molecular formula: C28H37N7O2. Mole weight: 503.64.
Palbociclib Impurity 027
An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Molecular formula: C27H35N7O2. Mole weight: 489.61.
Palbociclib Impurity 028
An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Molecular formula: C18H24N4O. Mole weight: 312.41.
Palbociclib Impurity 029
An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Synonyms: 1-(2-nitropyridin-3-yl)piperazine; 1566082-34-5; GS0805; EN300-2138375. Grades: 95%. CAS No. 1566082-34-5. Molecular formula: C9H12N4O2. Mole weight: 208.22.