BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
Hydroxocobalamin is an intermediate in the synthesis of Nitritocobalamin is a useful synthetic intermediate in the synthesis of Hydroxocobalamin Acetate; a physiological analog of vitamin B12 where the CN group is replaced with OH. Exists in aqueous solution as an equilibrium mixture of the hydroxy isomer and the ionic aqua isomer (aquacobalamin). Precursor of the coenzymes methylcobalamin and cobamamide. Coordination Compound. Vitamin (hematopoietic). Synonyms: Alpha Cobione; AlphaRedisol; Axlon; Ciplamin H; Hydroxo-cobalamin; Cobalex; Cobalin H; Cobinamide hydroxide phosphate 3'-ester with 5,6-dimethyl-1-α-D-ribofuranosylbenzimidazole Inner Salt; Codroxomin; Docclan; Docelan; Docevita; Droxomin; Ducobee Hy; Duradoce; Duralta-12; Hydrocobalamin; Hydrogrisevit; Hydrovit; Hydroxocobalamin; Hydroxocobalamine; Hydroxocobemine; Hydroxy vitamin B12; Hydroxycobalamin; Hydroxycobalamine; Hyxobamine; Idrogrisevit; Megamilbedoce; Neo-Betalin 12; Neo-Cytamen; Neo-Macrabin; Neo-Rojamin; OH-Duphar; Oxobemin; Primabalt RP; Redisol H; Sytobex H; Vibeden; Vitadurin; Vitamin B12a; α-(5,6-Dimethylbenzimidazolyl)hydroxocobamide. Grade: 96%. CAS No. 13422-51-0. Molecular formula: C62H89CoN13O15P. Mole weight: 1346.36.
Hydroxocobalamin acetate
One of the analog of Vitamin B12, which has been found to be related to the metabolism of cells in human body, especially DNA synthesis, amino acid as well as fatty acid metabolism. Synonyms: Acetatocobalamin; Docelan; Fresmin S. CAS No. 22465-48-1. Molecular formula: C64H91CoN13O16P. Mole weight: 1388.39.
Hydroxocobalamin hydrochloride
One of the analog of Vitamin B12, which has been found to be related to the metabolism of cells in human body, especially DNA synthesis, amino acid as well as fatty acid metabolism. Synonyms: Cobinamide, Co-hydroxy-, f-(dihydrogen phosphate), inner salt, 3'-ester with (5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole-κN3), hydrochloride (1:x); Cobinamide, dihydroxide, dihydrogen phosphate (ester), mono(inner salt), 3'-ester with 5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole, hydrochloride; Hydroxocobalamin Chloride; Hydroxy vitamin B12 hydrochloride; Hydroxycobalamin hydrochloride; Vitamin B12a hydrochloride; Hydroxycobalamin HCL. Grade: ≥95%. CAS No. 58288-50-9. Molecular formula: C62H89CoN13O15P.xHCl. Mole weight: 1346.36 (free base).
Hydroxocobalamin sulfate
One of the analog of Vitamin B12, which has been found to be related to the metabolism of cells in human body, especially DNA synthesis, amino acid as well as fatty acid metabolism. Synonyms: Hydroxycobalamin Sulphate; Hydroxocobalamin sulphate; Cobinamide, Co-hydroxy-, f-(dihydrogen phosphate), inner salt, 3'-ester with (5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole-κN3), sulfate (1:1) (salt); Cobinamide, hydroxide, dihydrogen phosphate (ester), inner salt, 3'-ester with 5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole, sulfate (1:1) (salt). Grade: ≥95%. CAS No. 167223-03-2. Molecular formula: C62H89CoN13O15P.H2O4S. Mole weight: 1444.44.
Hydroxyamine hydrochloride
Hydroxylamine hydrochloride is a compound used as a catalyst, copolymerization inhibitor, and swelling agent. Hydroxyamine hydrochloride is a selective monoamine oxidase (MAO) inhibitor used for inhibiting of platelet aggregation. Synonyms: Hydroxylamine HCl; hydroxyl amine hydrochloride; NH2OH hydrochloride. Grade: ≥97%. CAS No. 5470-11-1. Molecular formula: ClH4NO. Mole weight: 69.49.
Hydroxy Bendamustine
Hydroxy Bendamustine is an impurity of Bendamustine. Bendamustine is a DNA alkylating agent used for the treatment of chronic lymphocytic leukemia (CLL). Synonyms: 5-[(2-Chloroethyl)(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid; 4-(5-((2-Chloroethyl)(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic Acid. Grade: > 95%. CAS No. 109882-27-1. Molecular formula: C16H22ClN3O3. Mole weight: 339.83.
Hydroxy Bosentan
Hydroxy Bosentan is a metabolite of Bosentan. Synonyms: 4-(2-Hydroxy-1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-benzenesulfonamide; Ro 48-8634; Ro 48-5033. Grade: > 95%. CAS No. 253688-60-7. Molecular formula: C27H29N5O7S. Mole weight: 567.63.
Hydroxy Brimonidine
Hydroxy Brimonidine is an impurity of Brimonidine, a medication used to lower pressure in the eyes in patients who have glaucoma. Synonyms: Brimonidine EP Impurity G. Grade: 95%. CAS No. 1216379-05-3. Molecular formula: C11H12BrN5O. Mole weight: 310.15.
Hydroxychloroquine
Hydroxychloroquine is a synthetic antimalarial agent and it can inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Hydroxychloroquine efficiently inhibits SARS-CoV-2 infection in vitro. Uses: Antimalarials. Synonyms: Plaquenil; Oxichloroquine; Polirreumin; 7-Chloro-4-(4-(ethyl(2-hydroxyethyl)amino)-1-methylbutylamino)quinoline; WIN 1258; Win 1258-2. Grade: ≥97%. CAS No. 118-42-3. Molecular formula: C18H26ClN3O. Mole weight: 335.87.
Quensyl-1-acetate is an analog of Hydroxychloroquine Sulfate, an antimalarial; antirheumatic; lupus erythematosus suppressant. Synonyms: 2-[[4-[(7-Chloro-4-quinolinyl)amino]pentyl]ethylamino]ethanol 1-Acetate; 2-((4-((7-Chloroquinolin-4-yl)amino)pentyl)(ethyl)amino)ethyl Acetate. Grade: > 95%. CAS No. 47493-14-1. Molecular formula: C20H28ClN3O2. Mole weight: 377.92.
Hydroxychloroquine O-β-D-glucuronide
Hydroxychloroquine O-β-D-glucuronide is a metabolite of hydroxychloroquine, which is a medication primarily used for the prevention and treatment of malaria, as well as for the treatment of certain autoimmune diseases. Synonyms: 2-[[4-[(7-Chloro-4-quinolinyl)amino]pentyl]ethylamino]-ethyl β-D-glucopyranosiduronic acid; (2S,3S,4S,5R,6R)-6-(2-{[4-(7-Chloro-4-quinolylamino)pentyl]-N-ethylamino}ethoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid. Grade: ≥95%. CAS No. 2439157-39-6. Molecular formula: C24H34ClN3O7. Mole weight: 511.99.
Hydroxychloroquine O-Sulfate
Hydroxychloroquine O-Sulfate is an analogue and potential metabolite of the antimalarial drug Hydroxychloroquine. Studies suggest that there is increased uptake and retention of Hydroxychloroquine O-Sulfate in blood of rheumatoid arthritis subjects. Synonyms: 2-[[4-[(7-Chloro-4-quinolinyl)amino]pentyl]ethylamino]ethanol 1-(Hydrogen Sulfate) ; 2-[[4-[(7-Chloro-4-quinolyl)amino]pentyl]ethylamino]ethanol Sulfate. Grade: > 95%. CAS No. 103152-84-7. Molecular formula: C18H26ClN3O4S. Mole weight: 415.94.
Hydroxychloroquine Sulfate is an autophagy inhibitor that induces autophagic cell death. It also inhibits TLR9. Hydroxychloroquine is an antimalarial drug, and in combination with other medications, it can be used in the treatment of some autto-immune diseases. It has been used in emergency of COVID-19. Synonyms: 2-[[4-[(7-Chloro-4-quinolinyl)amino]pentyl]ethylamino]ethanol sulfate. Grade: > 95%. CAS No. 747-36-4. Molecular formula: C18H28ClN3O5S. Mole weight: 433.95.
Hydroxy Cobicistat
Hydroxy Cobicistat is an impurity in commercial preparation of Cobicistat. Synonyms: (S)-2-((hydroxy(((2-(2-hydroxypropan-2-yl)thiazol-4-yl)methyl)(methyl)amino)methylene)amino)-N-((2R,5R)-5-((hydroxy(thiazol-5-ylmethoxy)methylene)amino)-1,6-diphenylhexan-2-yl)-4-morpholinobutanimidic acid. Grade: > 95%. CAS No. 1051463-40-1. Molecular formula: C40H53N7O6S2. Mole weight: 792.02.
Hydroxy Darunavir
Hydroxy Darunavir is a metabolite of Daranavir. Synonyms: N-[3-[[(4-aminophenyl)sulfonyl](2-hydroxy-2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]carbamic Acid Hexahydrofuro[2,3-b]furan-3-yl Ester. Grade: > 95%. CAS No. 1130635-75-4. Molecular formula: C27H37N3O8S. Mole weight: 563.66.
Hydroxy Donepezil
An impurity of Donepezil, a medication for the treatment of Alzheimer's disease. Synonyms: 2,3-Dihydro-2-[hydroxy[1-(phenylmethyl)-4-piperidinyl]methyl]-5,6-dimethoxy-1H-inden-1-one; 2-[(1-Benzylpiperidin-4-yl)hydroxymethyl]-5,6-dimethoxyindan-1-one. Grade: > 95%. CAS No. 197010-20-1. Molecular formula: C24H29NO4. Mole weight: 395.5.
Hydroxy Ebastine
A metabolite of Ebastine. Synonyms: 4-[4-(Diphenylmethoxy)-1-piperidinyl]-1-[4-(2-hydroxy-1,1-dimethylethyl)phenyl]-1-butanone. Grade: > 95%. CAS No. 210686-41-2. Molecular formula: C32H39NO3. Mole weight: 485.67.
Hydroxy Empagliflozin
Hydroxy Empagliflozin is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: (1S)-1,5-Anhydro-1-C-[4-chloro-3-[hydroxy[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-D-glucitol; (2S,3R,4R,5S,6R)-2-(4-chloro-3-(hydroxy(4-(((S)-tetrahydrofuran-3-yl)oxy)phenyl)methyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol. CAS No. 2137418-13-2. Molecular formula: C23H27ClO8. Mole weight: 466.91.
Hydroxyethyl cellulose
Hydroxyethyl cellulose is a biopolymer often used as a thickener and adhesive. Uses: ·used as adhesives, bonding aids, filling cement admixtures ·used as coatings and optical brightener additives, coating polymers, filter control additives ·used as wet strength enhancer, protective colloid, rebound and slip reducing agent, rheology control modifier ·used as a gelling and thickening agent in the development of biological structures for hydrophobic drugs. Synonyms: Cellulose, 2-hydroxyethyl ether; Cellulose hydroxyethylate; 2-Hydroxyethyl cellulose; 2-Hydroxyethyl cellulose ether; Alcoramnosan; Cellulose hydroxyethyl ether; Hydroxyethyl cellulose ether; Hydroxyethyl ether cellulose; Hyetellose; Liporamnosan; Sanhec. CAS No. 9004-62-0.
Hydroxyethyl guanine
An impurity of Acyclovir. Acyclovir is an antiviral drug used for the treatment of infections caused by herpes simplex virus and herpes zoster virus. It acts via inhibiting the production of virus' DNA. Synonyms: 9-(2'-Hydroxyethyl)guanine; 9-(2-Hydroxyethyl)guanine. CAS No. 23169-33-7. Molecular formula: C7H9N5O2. Mole weight: 195.18.
Hydroxyethyl Phthalyl Amlodipine
An impurity of Amlodipine. Amlodipine is a long-acting dihydropyridine L-type calcium channel blocker used to lower blood pressure and prevent chest pain. Synonyms: 3-Ethyl 5-methyl 4-(2-chlorophenyl)-2-((2-(2-((2-hydroxyethyl)carbamoyl)benzamido)ethoxy)methyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate. Grade: ≥95%. Molecular formula: C30H34ClN3O8. Mole weight: 600.07.
Hydroxyethyl starch
Hydroxyethyl starch is a prominent pharmaceutical compound, standing resolute in its pivotal role as a plasma volume expander to aid in studying the distressing affliction of hypovolemia. Synonyms: 2-Hydroxyethyl starch; Hydroxypropyl starch; Hyspex; Hetastarch; Pentastarch; Voluven; Macrodex; Starch, 2-hydroxyethyl ether; 2-Hydroxyethyl starch ether; Starch hydroxyethyl ether; Tapioca starch hydroxyethyl ether; Tetraspan; Venofundin; Volekam. CAS No. 9005-27-0. Molecular formula: (C6H10O5)m(C2H5O)n.
Hydroxy famciclovir
An impurity of Famciclovir. Famciclovir is used for the treatment of various herpesvirus infections, most commonly for herpes zoster. Synonyms: 2-[2-(2-Amino-9H-purin-9-yl)ethyl]-1,2,3-propanetriol 1,3-Diacetate. Grade: > 95%. CAS No. 172645-79-3. Molecular formula: C14H19N5O5. Mole weight: 337.34.
Hydroxyfasudil
Hydroxyfasudil, formed through the metabolism action of Fasudil, could be useful in improving the symptoms of pulmonary hypertension for playing the role as an active Rho-kinase inhibitor and vasodilator. IC50: 0.12 uM and 0.17 uM for ROCK1 and ROCK2, res. Uses: Hydroxyfasudil could be useful in improving the symptoms of pulmonary hypertension for playing the role as an active rho-kinase inhibitor and vasodilator. Synonyms: 5-(1,4-Diazepane-1-sulfonyl)-1,2-dihydroisoquinolin-1-one; 1-[(1,2-Dihydro-1-oxo-5-isoquinolinyl)sulfonyl]hexahydro-1H-1,4-diazepine; Hydroxyfasudil. Grade: >99 %. CAS No. 105628-72-6. Molecular formula: C14H17N3O3S. Mole weight: 307.37.
Hydroxyfasudil Hydrochloride
Hydroxyfasudil Hydrochloride, an active metabolite of Fasudil, preferentially inhibits Rho-kinase and plays a central role in the pathogenesis of coronary artery spasm. It is reported to inhibit neutrophil migration and exhibit potent vasodilatory effects in vivo. Synonyms: HA 1100 hydrochloride; HA1100 hydrochloride; HA-1100 hydrochloride; 5-(1,4-diazepan-1-ylsulfonyl)-2~{H}-isoquinolin-1-one hydrochloride; 1-[(1,2-Dihydro-1-oxo-5-isoquinolinyl)sulfonyl]hexahydro-1H-1,4-diazepine hydrochloride. Grade: >98%. CAS No. 155558-32-0. Molecular formula: C14H18ClN3O3S. Mole weight: 343.826.
Hydroxy Flutamide
Hydroxyflutamide is an antiandrogen. It is the major active metabolite of flutamide found to inhibit the proliferation of estradiol-induced growth of MCF-7 breast cancer cells. It is an AR antagonist and is one of a few gold standard AR antagonists. Uses: Androgen antagonists. Synonyms: Hydroxyniphtholide; 2-Hydroxyflutamide; 2-Hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide; Sch 16423; α,α,α-Trifluoro-2-methyl-4'-nitro-m- lactotoluidide. Grade: > 95%. CAS No. 52806-53-8. Molecular formula: C11H11F3N2O4. Mole weight: 292.22.
Hydroxy Gliclazide
Hydroxy Gliclazide is the major hydroxylated metabolite of Gliclazide. Synonyms: N-[[(Hexahydrocyclopenta[c]pyrrol-2(1H)-yl)amino]carbonyl]-4-(hydroxymethyl)benzenesulfonamide; BenzenesulfonaMide, N-[[(hexahydrocyclopenta[c]pyrrol-2(1H)-yl)aMino]carbonyl]-4-(hydroxyMethyl)-. Grade: > 95%. CAS No. 87368-00-1. Molecular formula: C15H21N3O4S. Mole weight: 339.42.
Hydroxyhexamide
Hydroxyhexamide, a derivative of acetohexamide, obtained as a pharmacologically active metabolite of acetohexamide. It might be used in the treatment of type 2 diabetes as a Hypoglycemic agent. Uses: Hydroxyhexamide is a pharmacologically active metabolite of acetohexamide and could be used as a hypoglycemic agent against type 2 diabetes. Synonyms: HYDROXYHEXAMIDE; AC1L2C6O; CHEMBL2105052; HY-B1103. Grade: ≥ 95%. CAS No. 3168-1-2. Molecular formula: C15H22N2O4S. Mole weight: 326.41.
Hydroxy Iloperidone
A hydroxylated metabolite of Iloperidone. Uses: Hydroxy iloperidone is produced through metabolism of iloperidone and could have probable antipsychotic effect. Synonyms: 4-[3-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]propoxy]-3-methoxy-α-methylbenzenemethanol; P 88; P 88-8991. Grade: > 95%. CAS No. 133454-55-4. Molecular formula: C24H29FN2O4. Mole weight: 428.51.
Hydroxy Itraconazole
A metabolite of Itraconazole, an orally active antimycotic structurally related to Ketoconazole. Uses: Hydroxy itraconazole is a metabolite of itraconazole and could be used as an antimycotic. Synonyms: 4-[4-[4-[4-[[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(2-hydroxy-1-methylpropyl)-3H-1,2,4-triazol-3-one. Grade: > 95%. CAS No. 112559-91-8. Molecular formula: C35H38Cl2N8O5. Mole weight: 721.65.
Hydroxy Ivabradine
An impurity of Ivabradine, a medication used to reduce the risk of hospitalization for worsening heart failure in adult patients with stable, symptomatic chronic heart failure. Synonyms: 1,3,4,5-Tetrahydro-3-(3-hydroxypropyl)-7,8-dimethoxy-2H-3-benzazepin-2-one; 3-(3-Hydroxypropyl)-7,8-dimethoxy-4,5-dihydro-1H-benzo[d]azepin-2(3H)-one. Grade: > 95%. CAS No. 1235547-07-5. Molecular formula: C15H21NO4. Mole weight: 279.34.
Hydroxy Loxoprofen
An impurity of Loxoprofen. Loxoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduce the synthesis of prostaglandins from arachidonic acid. Synonyms: Benzeneacetic acid, 4-[(2-hydroxycyclopentyl)?methyl]?-α-methyl-. Grade: >95%. CAS No. 83599-40-0. Molecular formula: C15H20O3. Mole weight: 248.32.
Hydroxyloxoprofen Alkoxy Glucuronide
Hydroxyloxoprofen Alkoxy Glucuronide is a derivative of Loxoprofen, a non-selective nonsteroidal anti-inflammatory drug (NSAID) that has been effective in reducing atherosclerosis in mice by reducing inflammation. Synonyms: (2R,3R,4R,5S,6S)-6-(((1S,2R)-2-(4-(1-Carboxyethyl)benzyl)cyclopentyl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic Acid; Hydroxyloxoprofen Glucuronide. Grade: > 95%. Molecular formula: C21H28O9. Mole weight: 424.44.
Hydroxy Loxoprofen-d6
Hydroxy Loxoprofen-d6 is a labelled impurity of Hydroxy Loxoprofen. Loxoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduce the synthesis of prostaglandins from arachidonic acid. Grade: > 95%. Molecular formula: C15H14O3D6. Mole weight: 254.36.
Hydroxymethyl Alosetron
A derivative of Alosetron. Synonyms: Alosetron M5; 2,3,4,5-Tetrahydro-2-[[5-(hydroxymethyl)-1H-imidazol-4-yl]methyl]-5-methyl-1H-pyrido[4,3-b]indol-1-one. Grade: > 95%. CAS No. 863485-46-5. Molecular formula: C17H18N4O2. Mole weight: 310.36.
Hydroxymethyl Clenbuterol
Hydroxymethyl Clenbuterol is a β-agonist which can be used as a growth promoter in farm animals. Other β2-Agonists with effects on animal growth are: Mabuterol, Mapenterol, Clenproperol, Terbutaline, Clenbuterol, Salbutamol, Clenpenterol, Bromobuterol. Synonyms: 4-Amino-3,5-dichloro-α-[[(2-hydroxy-1,1-dimethylethyl)amino]methyl]benzenemethanol; NA 1141; HMCBT. Grade: > 95%. CAS No. 38339-18-3. Molecular formula: C12H18Cl2N2O2. Mole weight: 293.19.
Hydroxymethylclenbuterol hydrochloride
Hydroxymethylclenbuterol hydrochloride is an impurity of Clenbuterol. Clenbuterol, marketed as Dilaterol, Spiropent, Ventipulmin, and also generically as Dilaterol and Spiropent, a representative of the class of beta-adrenergic agents, had been used as a tocolytic, bronchodilator, and heart tonics in human and veterinary medicine. Synonyms: 2-[2-(4-Amino-3,5-dichlorophenyl)-2-hydroxyethylamino]-2-methylpropan-1-ol hydrochloride. CAS No. 37162-89-3. Molecular formula: C12H19Cl3N2O2. Mole weight: 329.653.
Hydroxymethyl Dasatinib
Hydroxymethyl Dasatinib is an oxidative metabolite of Dasatinib (M24 metabolite), used in the treatment of cancers and immune diseases. Synonyms: N-[2-Chloro-6-(hydroxymethyl)phenyl]-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide. Grade: > 95%. CAS No. 910297-58-4. Molecular formula: C22H26ClN7O3S. Mole weight: 504.
Hydroxymethyl Emtricitabine
Hydroxymethyl Emtricitabine is an impurity of Emtricitabine, which is a nucleoside reverse transcriptase inhibitor for the treatment of HIV infection in adults and children. Synonyms: 5-Fluoro-1-((2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-4-((hydroxymethyl)amino)-2(1H)-pyrimidinone. Molecular formula: C9H12FN3O4S. Mole weight: 277.27.
Hydroxy Methyl Lamivudine
An impurity of Lamivudine, which is a potent nucleoside analog reverse transcriptase inhibitor, used for treatment of chronic HBV and HIV/AIDS. Synonyms: 4-[(Hydroxymethyl)amino]-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone; Lamivudine Impurity 35; 1-((2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl)-4-((hydroxymethyl)amino)pyrimidin-2(1H)-one; Lamivudine Formaldehyde Adduct Impurity. Grade: ≥95%. CAS No. 1904611-13-7. Molecular formula: C9H13N3O4S. Mole weight: 259.28.
Hydroxy Methyl Linagliptin
An impurity of Linagliptin, a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes. Synonyms: (R,E)-8-(3-Aminopiperidin-1-yl)-1-((4-ethylquinazolin-2-yl)methyl)-7-(4-hydroxy-3-methylbut-2-en-1-yl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione; 8-[(3R)-3-Aminopiperidin-1-yl]-7-[(2E)-4-hydroxy-3-methylbut-2-en-1-yl]-3-methyl-1-[(4-ethylquinazolin-2-yl)methyl]-3,7-dihydro-1H-purine-2,6-dione. Grade: ≥95%. Molecular formula: C27H34N8O3. Mole weight: 518.61.
Hydroxymethyl Tolperisone Hydrochloride
One of the impurities of Tolperisone, which has been found to be effective as a muscle relax agent. Synonyms: 1-[4-(Hydroxymethyl)phenyl]-2-methyl-3-(1-piperidinyl)-1-propanone Hydrochloride. CAS No. 352233-14-8. Molecular formula: C16H23NO2.HCl. Mole weight: 297.83.
Hydroxy Metronidazole
An impurity of Metronidazole. Metronidazole is an antibacterial in the treatment of rosacea. Antiprotozoal (trichomonas). A potential human carcinogen. Synonyms: 2-(Hydroxymethyl)-5-nitro-1H-imidazole-1-ethanol; Metronidazole-OH; 1-(2-Hydroxyethyl)-2-(hydroxymethyl)-5-nitroimidazole; Hydroxymetronidazole. Grade: > 95%. CAS No. 4812-40-2. Molecular formula: C6H9N3O4. Mole weight: 187.16.
Hydroxy Nefazodone-d5 HCl
A labelled Nefazodone hydrochloride, which is a selective serotonin 5-HT2 receptor antagonist. Synonyms: 2-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-2,4-dihydro-5-(1-hydroxyethyl)-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one- d5 Dihydrochloride; OH-NEF Dihydrochloride. Grade: > 95%. Molecular formula: C25H27D5ClN5O3·HCl. Mole weight: 527.51.
Hydroxy Nefazodone Dihydrochloride
Hydroxy Nefazodone Dihydrochloride is a metabolite of Nefazodone, which is a potent serotonin 5-HT2A receptor and 5-HT2C receptor antagonist and weak serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI) used as an atypical antidepressant. Synonyms: 2-{3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl}-5-(1-hydroxyethyl)-4-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one dihydrochloride; 3H-1,2,4-Triazol-3-one, 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-2,4-dihydro-5-(1-hydroxyethyl)-4-(2-phenoxyethyl)-, hydrochloride (1:2); Hydroxy Nefazodone HCl. Grade: ≥95%. Molecular formula: C25H32ClN5O3.2HCl. Mole weight: 558.93.
Hydroxy Nefazodone hydrochloride
Hydroxy Nefazodone hydrochloride is a metabolite of Nefazodone, which is a potent serotonin 5-HT2A receptor and 5-HT2C receptor antagonist and weak serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI) used as an atypical antidepressant. Synonyms: 2-{3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl}-5-(1-hydroxyethyl)-4-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one hydrochloride; 3H-1,2,4-Triazol-3-one, 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-2,4-dihydro-5-(1-hydroxyethyl)-4-(2-phenoxyethyl)-, hydrochloride (1:1). Grade: ≥95%. CAS No. 98159-83-2. Molecular formula: C25H32ClN5O3.HCl. Mole weight: 522.47.
Hydroxy pentoxifylline
Pentoxifylline is a competitive nonselective phosphodiesterase inhibitor. It improves red blood cell deformability, reduces blood viscosity and decreases the potential for platelet aggregation and thrombus formation. It also reduces AST and ALT levels and may improve liver histological scores in patients with NALFD/NASH, but did not appear to affect cytokines. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: (±)-Lisofylline; BL 194; CT-1501R; LSF; 3,7-dihydro-1-(5-hydroxyhexyl)-3,7-dimethyl-1H-purine-2,6-dione. Grade: > 95%. CAS No. 6493-6-7. Molecular formula: C13H20N4O3. Mole weight: 280.33.
Hydroxy Pioglitazone
Hydroxy pioglitazone is a major metabolite of pioglitazone, a PPARγ agonist. Pioglitazone is a medication indicated for type 2 diabetes. Synonyms: Hydroxypioglitazone; Leriglitazone; 5-[[4-[2-[5-(1-hydroxyethyl)pyridin-2-yl]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione. Grade: ≥95%. CAS No. 146062-44-4. Molecular formula: C19H20N2O4S. Mole weight: 372.44.
Hydroxy Pioglitazone-d4 (M-II) (deuterated)
A deuterated metabolite of Pioglitazone which is used to lower blood glucose levels in the treatment of diabetes mellitus type 2 (T2DM). Grade: > 95%. Molecular formula: C19H16N2O4SD4. Mole weight: 376.47.
Hydroxy Pioglitazone (M-IV) β-D-Glucuronide
An impurity of Pioglitazone which is a thiazolidinedione compound with anti-inflammatory and antiarteriosclerotic effects. Synonyms: 1-[6-[2-[4-[(2,4-Dioxo-5-thiazolidinyl)methyl]phenoxy]ethyl]-3-pyridinyl]ethyl b-D-glucopyranosiduronic acid. Grade: > 95%. CAS No. 625853-76-1. Molecular formula: C25H28N2O10S. Mole weight: 548.56.
Hydroxypioglitazone (M-IV) hydrochloride
Hydroxypioglitazone (M-IV) hydrochloride is the salt of an active metabolite of Pioglitazone (M-IV), a PPARγ agonist used in the treatment of diabetes mellitus type 2. In comparison with Pioglitazone, it has modest antihyperglycemic activity and more potent stimulating activity in lipid synthesis. Synonyms: 1-Hydroxy Pioglitazone Hydrochloride; 5-[4-[2-[5-(1-hydroxyethyl)-2-pyridyl]ethoxy]benzyl]-2,4-thiazolidinedione hydrochloride. Grade: 99%. CAS No. 146062-46-6. Molecular formula: C19H20N2O4S.HCl. Mole weight: 408.9.
Hydroxy Pioglitazone (M-VII)
A metabolite of Pioglitazone which is a thiazolidinedione compound with antiinflammatory and antiarteriosclerotic effects. Synonyms: Hydroxy Pioglitazone (M-VII); 625853-72-7; 5-[[4-[2-[5-(2-hydroxyethyl)pyridin-2-yl]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione; 5-[(4-{2-[5-(2-Hydroxyethyl)pyridin-2-yl]ethoxy}phenyl)methyl]-1,3-thiazolidine-2,4-dione; Hydroxy pioglitazone(m-vII); SCHEMBL5805283; DTXSID10849604; 5-[[4-[2-[5-(2-Hydroxyethyl)-2-pyridinyl]ethoxy]phenyl]methyl]-2,4-thiazolidinedione; FT-0670010. Grade: > 95%. CAS No. 625853-72-7. Molecular formula: C19H20N2O4S. Mole weight: 372.45.
Hydroxy pioglitazone (M-VII) b-D-glucuronide
Hydroxy pioglitazone (M-VII) b-D-glucuronide is a biomedical compound used in the treatment of diabetes. It acts as a metabolite of pioglitazone, an oral antidiabetic medication, and functions by enhancing insulin sensitivity. This product aids in maintaining blood sugar levels and managing complications associated with diabetes, promoting overall well-being. Synonyms: 2-[6-[2-[4-[(2,4-Dioxo-5-thiazolidinyl)methyl]phenoxy]ethyl]-3-pyridinyl]ethyl b-D-glucopyranosiduronic acid. CAS No. 625853-75-0. Molecular formula: C25H28N2O10S. Mole weight: 548.56.
Hydroxypiperaquine-d5
A deuterated metabolite of Piperaquine which is a bisquinoline antimalarial drug highly active against chloroquine-resistant Plasmodium falciparum and Plasmodium vivax. Grade: > 95%. Molecular formula: C29H27Cl2N6OD5. Mole weight: 556.55.
Hydroxypropyl cellulose
In oral products, hydroxypropyl cellulose is primarily used in tablets as a binder, film coating, and extended-release-matrix former. Hydroxypropyl cellulose is also used in the microencapsulation process and as a thickener. In topical formulations, hydroxypropyl cellulose is used in transdermal patches and ophthalmic preparations. It is also used as an emulsifier and stabilizer in cosmetics and foods. Synonyms: Cellulose, 2-hydroxypropyl ether; Hydroxypropylcellulose; Cellulose, hydroxypropyl ether; E463; hydroxypropylcellulosum; Klucel; Nisso HPC; 2-Hydroxypropyl cellulose; Hydroxypropyl cellulose ether; Hydroxypropyl ether of cellulose; Hyprolose; O-(2-Hydroxypropyl)cellulose; O-(Hydroxypropyl)cellulose; Oxypropylated cellulose; Performax 1426; PM 50 (polymer); R 1000 (cellulose derivative). CAS No. 9004-64-2.
Hydroxypropyl Chitosan
Hydroxypropyl Chitosan is an antibacterial used to make organic rectorite-based nanofibrous mats with bacterial inhibition. Hydroxypropyl Chitosan has been shown to exhibit inhibitory effects on the levels of Fe, Zn and Ca in liver, heart, lung, spleen, kidney and femur at high dosages in mice. Synonyms: Chitosan, 2-hydroxypropyl ether; Chitofilmer; Chitofilmer HV; 2-Hydroxypropyl Ether Chitosan. Grade: ≥95%. CAS No. 84069-44-3.
Hydroxyregorafenib
A derivative of Regorafenib.Regorafenib is a multi-kinase inhibitor which targets angiogenic, stromal and oncogenic receptor tyrosine kinase. It shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition. Grade: > 95%. Molecular formula: C21H15ClF4N4O4. Mole weight: 498.82.
Hydroxystilbamidine
Hydroxystilbamidine is a cationic dye with antifungal, antitrypanosomal, antimalarial, and carcinostatic activities. Synonyms: Oxistilbamidinum; 4-(4-Carbamimidoylstyryl)-3-hydroxybenzimidamide; 2-Hydroxy-4,4'-diguanylstilbene; 2-Hydroxy-4,4'-stilbenedicarboxamidine; OHSA; (E)-hydroxystilbamidine. CAS No. 495-99-8. Molecular formula: C16H16N4O. Mole weight: 280.32.
Hydroxy Sulfentrazone
One of the impurities of Sulfentrazone, which is a herbicide and could control sedges in turfgrass effectively. Synonyms: Methanesulfonamide, N-[2,?4-dichloro-5-[4-(difluoromethyl)?-4,?5-dihydro-3-(hydroxymethyl)?-5-oxo-1H-1,?2,?4-triazol-1-yl]?phenyl]?-. Grade: > 95%. CAS No. 134390-99-1. Molecular formula: C11H10Cl2F2N4O4S. Mole weight: 403.19.
Hydroxyterbinafine b-D-glucuronide
Hydroxyterbinafine b-D-glucuronide, a potent biomedical product originating from terbinafine, possesses remarkable antifungal properties indispensable for combating dermatophyte-induced fungal infections. Renowned for its metabolite status, this compound unveils an exceptional pharmacological profile, exuding heightened efficacy and therapeutic potency. Its unprecedented formulation, characterized by amplified bioavailability, serves as a pivotal catalyst in effectively managing afflictions like onychomycosis, tinea pedis, and tinea corporis. Synonyms: β-D-Glucopyranosiduronic acid, 2,2-dimethyl-7-[methyl(1-naphthalenylmethyl)amino]-5-hepten-3-ynyl, (E)-. CAS No. 99473-12-8. Molecular formula: C27H33NO7. Mole weight: 483.57.
Hydroxy Tetrabenazine
A mixture of two metabolite impurities of Tetrabenazine, which is a VMAT-2 inhibitor and has been found to be effective in the treatment of hyperkinetic movement disorder at some extent. Synonyms: rac-(2,3)-Dihydro Tetrabenazine [Cis/Trans Mixture]; Mixture of cis and trans Isomers. Grade: > 95%. CAS No. 3466-75-9. Molecular formula: C19H29NO3. Mole weight: 319.45.