BOC Sciences 8 - Products

BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.

Product
RO1138452 RO1138452 is one of the most potent high-affinity ligands and functional antagonists for the human IP (prostacyclin) receptor. It exhibits no affinity at other prostanoid receptors (EP1-4, FP and TP) in a radioligand binding assay. RO1138452 antagonizes the carbaprostacyclin-induced activation of human neuroblastoma adenylate cyclase, blocking cyclic AMP accumulation in a dose-dependent manner. Synonyms: RO-1138452; RO1138452; RO 1138452; CAY10441; CAY-10441; CAY 10441; N-(4-(4-Isopropoxybenzyl)phenyl)-4,5-dihydro-1H-imidazol-2-amine. CAS No. 221529-58-4. Molecular formula: C19H23N3O. Mole weight: 309.413. BOC Sciences 8
RO-5028442 RO-5028442 is a potent and brain-penetrant hV1a antagonist. RO-5028442 is undergoing clinical trials for autistic disorder therapy. Synonyms: RO-5028442; RO 5028442; RO5028442. [6-chloro-1-[2-(dimethylamino)ethyl]indol-3-yl]-spiro[1H-2-benzofuran-3,4'-piperidine]-1'-ylmethanone. CAS No. 920022-47-5. Molecular formula: C25H28ClN3O2. Mole weight: 437.968. BOC Sciences 8
Ro 61-8048 Potent and competitive kynurenine 3-hydroxylase inhibitor (IC50 = 37 nM). Shows antidystonic, anticonvulsant and neuroprotective effects in vivo. Blood-brain barrier permeable. Orally active. Synonyms: Ro61-8048; Ro 61-8048; Ro-61-8048; Ro618048; Ro 618048; Ro-618048. Grades: >98%. CAS No. 199666-03-0. Molecular formula: C17H15N3O6S2. Mole weight: 421.45. BOC Sciences 8
Rociletinib Rociletinib is a third-generation irreversible kinase inhibitor of epidermal growth factor receptor (EGFR). Rociletinib was shown to inhibit the proliferation of non-small cell lung cancer (NSCLC) cells expressing mutant EGFR. It also exhibits anti-tumor activity in NSCLC EGFR mutant xenograft models. Synonyms: CO-1686; CO1686; CO 1686; AVL-301; AVL 301; AVL301; CNX-419; CNX 419; CNX419; N-[3-[[2-[4-(4-acetylpiperazin-1-yl)-2-methoxyanilino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]phenyl]prop-2-enamide. CAS No. 1374640-70-6. Molecular formula: C27H28F3N7O3. Mole weight: 555.562. BOC Sciences 8
Rocuronium bromide Rocuronium Bromide is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant. Synonyms: ORG 9426; ORG-9426; ORG9426. Grades: >98%. CAS No. 119302-91-9. Molecular formula: C32H53N2O4.Br. Mole weight: 609.68. BOC Sciences 8
Rocuronium bromide EP impurity F An impurity of Rocuronium. Rocuronium is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia to facilitate endotracheal intubation by providing skeletal muscle relaxation. Synonyms: 2-Pyrrolidinyl-3-acetyl Desmorpholinylrocuronium Bromide; 1-[(2β, 3α, 5α, 16β, 17β)-3, 17-Bis(acetyloxy)-2-(1-pyrrolidinyl)androstan-16-yl]-1-(2-propen-1-yl)-pyrrolidinium. Grades: > 95%. CAS No. 1190105-66-8. Molecular formula: C34H55N2O4.Br. Mole weight: 635.72. BOC Sciences 8
Rocuronium EP Impurity A An impurity of Rocuronium. Rocuronium is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia to facilitate endotracheal intubation by providing skeletal muscle relaxation. Synonyms: 2β-(4-Morpholinyl)-16β-(1-pyrrolidinyl)-5α-androstane-3α,17β-diol 17-Acetate; (2β, 3α, 5α, 16β, 17β)-2-(4-Morpholinyl)-16-(1-pyrrolidinyl)androstane-3, 17-diol 17-Acetate; Desallyl Rocuronium. Grades: 99 %. CAS No. 119302-24-8. Molecular formula: C29H48N2O4. Mole weight: 488.72. BOC Sciences 8
Rocuronium EP Impurity C An impurity of Rocuronium. Rocuronium is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia to facilitate endotracheal intubation by providing skeletal muscle relaxation. Synonyms: 17-Desacetyl Rocuronium Bromide; 1-[(2β, 3α, 5α, 16β, 17β)-3, 17-Dihydroxy-2-(4-morpholinyl)androstan-16-yl]-1-(2-propenyl)pyrrolidinium Bromide. Grades: > 95%. CAS No. 119302-86-2. Molecular formula: C30H51N2O3.Br. Mole weight: 567.65. BOC Sciences 8
Rocuronium EP Impurity E An impurity of Rocuronium. Rocuronium is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia to facilitate endotracheal intubation by providing skeletal muscle relaxation. Synonyms: 2-Pyrrolidinyl Desmorpholinylrocuronium Bromide; 1-[(2β, 3α, 5α, 16β, 17β)-17-(Acetyloxy)-3-hydroxy-2-(1-pyrrolidinyl)androstan-16-yl]-1-(2-propen-1-yl)-pyrrolidinium Bromide. Grades: > 95%. CAS No. 1190105-65-7. Molecular formula: C32H53N2O3. Br. Mole weight: 593.69. BOC Sciences 8
Rocuronium EP Impurity G An impurity of Rocuronium. Rocuronium is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia to facilitate endotracheal intubation by providing skeletal muscle relaxation. Synonyms: 2β-(4-Morpholinyl)-16β-(1-pyrrolidinyl)-5α-androstane-3α,17β-diol; (2β, 3α, 5α, 16β, 17β)-2-(4-Morpholinyl)-16-(1-pyrrolidinyl)androstan-3, 17-diol; Desacetyl Desallyl Rocuronium. Grades: 99 %. CAS No. 119302-20-4. Molecular formula: C27H46N2O3. Mole weight: 446.68. BOC Sciences 8
Rocuronium EP Impurity H An impurity of Rocuronium. Rocuronium is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia to facilitate endotracheal intubation by providing skeletal muscle relaxation. Synonyms: 1,2-Dehydro-3-oxo Rocuronium Bromide; Rocuronium Bromide Impurity 21; 1-[(5α,16β,17β)-17-(Acetyloxy)-2-(4-morpholinyl)-3-oxoandrost-1-en-16-yl]-1-(2-propen-1-yl)-pyrrolidinium Bromide. Grades: > 95%. CAS No. 1190105-67-9. Molecular formula: C32H49N2O4.Br. Mole weight: 605.65. BOC Sciences 8
Rofecoxib Rofecoxib is a COX-2 inhibitor (IC50s = 26 nM and > 50 μM in human osteosarcoma cells). Uses: Cyclooxygenase 2 inhibitors. Synonyms: MK966; MK966; MK 966; MK0966; MK0966; MK 0966; Rofecoxib; brand name: Vioxx; Ceoxx; Ceeoxx. 4-[4-(methylsulfonyl)phenyl]-3-phenyl-2(5H)-furanone. Grades: > 95%. CAS No. 162011-90-7. Molecular formula: C17H14O4S. Mole weight: 314.4. BOC Sciences 8
Rolapitant Rolapitant is a selective NK1 receptor antagonist (antagonist for the NK1 receptor). Synonyms: (5S, 8S) -8- ( ( (R) -1- (3, 5-bis (trifluoromethyl) phenyl) ethoxy) methyl) -8-phenyl-1, 7-diazaspiro[45]decan-2-one; SCH619734; SCH-619734; SCH 619734; Varubi. Grades: >95%. CAS No. 552292-08-7. Molecular formula: C25H26F6N2O2. Mole weight: 500.49. BOC Sciences 8
Romifidine hydrochloride Romifidine is an α2 agonist used as a sedative and analgesic in horses. Synonyms: N-(2-Bromo-6-fluorophenyl)-4,5-dihydro-1H-imidazol-2-amine hydrochloride; STH 2130Cl; Sedivet. CAS No. 65896-14-2. Molecular formula: C9H10BrClFN3. Mole weight: 294.55. BOC Sciences 8
Rostafuroxin Rostafuroxin is a Na+/K+ ATPase modulator that treats hypertension by normalizing renal Na+/K+ ATPase pump function. Synonyms: PST-2238; PST 2238; (3S,5R,8R,9S,10S,13S,14S,17S)-17-(furan-3-yl)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,15,16-dodecahydro-1H-cyclopenta[a]phenanthrene-3,14,17-triol. Grades: 98.07%. CAS No. 156722-18-8. Molecular formula: C23H34O4. Mole weight: 374.521. BOC Sciences 8
Rosuvastatin (6S)-Lactone Impurity An impurity of Rosuvastatin. Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Synonyms: N-[(6S)-8-Fluoro-5,6-dihydro-4-(1-methylethyl)-6-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]benzo[h]quinazolin-2-yl]-N-methylmethane sulfonamide; N-((S)-8-fluoro-6-((2S,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)-4-isopropyl-5,6-dihydrobenzo[h]quinazolin-2-yl)-N-methylmethanesulfonamide. CAS No. 854898-47-8. Molecular formula: C22H26FN3O5S. Mole weight: 463.52. BOC Sciences 8
Rotigotine Hydrochloride The hydrochloride salt form of Rotigotine which is a dopamine D2 and D3 receptor agonist and has been shown to be effective in the treatment of Parkinson's disease. IC50: 13 nM and 0.71 nM for D2 and D3 receptor respectively. Uses: The hydrochloride salt form of rotigotine which is a dopamine d2 and d3 receptor agonist and has been shown to be effective in the treatment of parkinson's disease. Synonyms: Rotigotine hydrochloride; Rotigotine HCl; Rotigotine (Hydrochloride); (S)-6-(Propyl(2-(thiophen-2-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride; (6S)-6-[propyl(2-thiophen-2-ylethyl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride. Grades: >99 %. CAS No. 125572-93-2. Molecular formula: C19H26ClNOS. Mole weight: 351.93. BOC Sciences 8
Roxatidine hydrochloride An impurity of potent Rotundine. Rotundine is a selective dopamine D1 receptor antagonist. Synonyms: Acetamide, 2-hydroxy-N-(3-(3-(1-piperidinylmethyl)phenoxy)propyl)-, monohydrochloride. CAS No. 97900-88-4. Molecular formula: C17H27ClN2O3. Mole weight: 342.86. BOC Sciences 8
(R)-Oxybutynin Chloride (R)-Oxybutynin Chloride is an impurity of Oxybutynin, which is a medication used to treat overactive bladder. Synonyms: (R)-α-Phenylcyclohexaneglycolic Acid 4-(Diethylamino)-2-butynyl Ester, Hydrochloride. Grades: 98%. CAS No. 1207344-05-5. Molecular formula: C22H32ClNO3. Mole weight: 393.95. BOC Sciences 8
(R)-Ranolazine (R)-Ranolazine is the R-isomer of Ranolazine, which is a medication used to treat heart-related chest pain. Synonyms: 1-Piperazineacetamide, N-(2,6-dimethylphenyl)-4-[(2R)-2-hydroxy-3-(2-methoxyphenoxy)propyl]-; (R)-N-(2,6-Dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]-1-piperazineacetamide; (+)-Ranolazine. Grades: ≥95%. CAS No. 114246-80-9. Molecular formula: C24H33N3O4. Mole weight: 427.54. BOC Sciences 8
(R,R)-Hydroxy Bupropion (R,R)-Hydroxy Bupropion is the (R,R) Enantiomer metabolite of Bupropion, an antidepressant. Synonyms: (2R,3R)-2-(3-Chlorophenyl)-3,5,5-trimethyl-2-morpholinol; (2R-cis)-2-(3-Chlorophenyl)-3,5,5-trimethyl-2-morpholinol; (-)-(2R,3R)-2-(3-Chlorophenyl)-3,5,5-trimethyl-2-morpholinol; Bupropion Morpholinol (2R,3R)-Isomer. Grades: > 95%. CAS No. 192374-15-5. Molecular formula: C13H18ClNO2. Mole weight: 255.75. BOC Sciences 8
(R,R)-Isophytol (R,R)-Isophytol is an impurity of Vitamin K1, which is a fat-soluble vitamin commonly used in dietary supplement for the treatment of bleeding disorders. Synonyms: Vitamin K1 Impurity 22; 3-Amboisophytol; (2RS,7R,11R)-Isophytol; (7R,11R)-3,7,11,15-Tetramethyl-1-hexadecen-3-ol. Grades: ≥95%. CAS No. 395645-30-4. Molecular formula: C20H40O. Mole weight: 296.53. BOC Sciences 8
(R,R)-Montelukast Bis-sulfide Cas No. 1187586-61-3. BOC Sciences 8
(R)-(+)-Ropivacaine hydrochloride (R)-(+)-Ropivacaine hydrochloride is an isomer of Ropivacaine, a local anaesthetic drug belonging to the amino amide group. Synonyms: (R)-Ropivacaine Hydrochloride; Ropivacaine hydrochloride, (R)-; USP Ropivacaine Related Compound B; Ropivacaine EP Impurity G. Grades: 95%. CAS No. 112773-90-7. Molecular formula: C17H27ClN2O. Mole weight: 310.86. BOC Sciences 8
(R,R)-Palonosetron HCl An impurity of Palonosetron which is the most effective of the 5-HT3 antagonists in controlling delayed CINV nausea and vomiting. Synonyms: Palonosetron (R,R)-Isomer (HCl Salt); (3aR)-2-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]-2,3,3a,4,5,6-hexahydro-1H-benz[de]isoquinolin-1-one HCl. Grades: > 95%. CAS No. 135729-75-8. Molecular formula: C19H24N2O.HCl. Mole weight: 332.86. BOC Sciences 8
[R-(R*,R*)]-(1,2-Dihydroxypropyl)phosphonic Acid [R-(R*,R*)]-(1,2-Dihydroxypropyl)phosphonic Acid is one of fosfomycin impurities. Fosfomycin is an antibiotic that exerts a broad spectrum of antibacterial activity. It was produced by certain Streptomyces species. Synonyms: Fosfomycin EP Impurity A. Grades: 96%. CAS No. 132125-60-1. Molecular formula: C3H9O5P. Mole weight: 156.07. BOC Sciences 8
(R,S)-4-Hydroxy Cyclophosphamide (R,S)-4-Hydroxy Cyclophosphamide is a metabolite of Cyclophosphamide. Synonyms: (2R,4S)-rel-2-[Bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorin-4-ol 2-Oxide. Grades: > 95%. CAS No. 61903-30-8. Molecular formula: C7H15Cl2N2O3P. Mole weight: 277.09. BOC Sciences 8
(R,S)-Ethambutol An isomer of Ethambutol. Ethambutol is a medication primarily used to treat tuberculosis. Synonyms: (R,S)-Ethambutol; meso-N, N'-Bis[1- (hydroxymethyl) propyl]ethylenediamine; USP Ethambutol Related Compound A. Grades: > 95%. CAS No. 10054-06-5. Molecular formula: C10H24N2O2. Mole weight: 204.31. BOC Sciences 8
(R,S)-Montelukast Bis-sulfide Cas No. 1187586-58-8. BOC Sciences 8
(R,S)-Norcotinine (R,S)-Norcotinine is a metabolite of (+/-)-Cotinine. Synonyms: 5-(3-Pyridinyl)-2-pyrrolidinone; (+/-)-Demethylcotinine; (+/-)-Norcotinine. Grades: > 95%. CAS No. 17708-87-1. Molecular formula: C9H10N2O. Mole weight: 162.19. BOC Sciences 8
(R,S)-Norcotinine N-Oxide (R,S)-Norcotinine N-Oxide is a metabolite of Nicotine in human blood plasma. Synonyms: 5-(1-Oxido-3-pyridinyl)-2-pyrrolidinone; (+/-)-5-(3-Pyridinyl)-2-pyrrolidinone N-Oxide. Grades: > 95%. CAS No. 101708-63-8. Molecular formula: C9H10N2O2. Mole weight: 178.19. BOC Sciences 8
(R,S)-Palonosetron HCl An impurity of Palonosetron which is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Uses: Antiemetics. Synonyms: Palonosetron (R,S)-Isomer (HCl Salt); (3aR)-2-[(3S)-1-Azabicyclo[2.2.2]oct-3-yl]-2,3,3a,4,5,6-hexahydro-1H-benz[de]isoquinolin-1-one HCl. Grades: > 95%. CAS No. 135755-51-0. Molecular formula: C19H24N2O.HCl. Mole weight: 332.86. BOC Sciences 8
(RS,SR) 3-[[2-(4-Chlorophenyl)-2-cyclopentyl-2-hydroxyacetyl]oxy]-1,1-dimethylpyrrolidinium Bromide BOC Sciences 8
(R)-Terazosin One impurity of Terazosin, which is a piperazine derivative and has been found to be an α-1-adrenergic blocker. Synonyms: (R)-Terazosin; 109351-34-0; [4-(4-Amino-6,7-Dimethoxyquinazolin-2-Yl)piperazin-1-Yl][(2r)-Tetrahydrofuran-2-Yl]methanone[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-[(2R)-oxolan-2-yl]methanone; (R)-(4-(4-AMINO-6,7-DIMETHOXYQUINAZOLIN-2-YL)PIPERAZIN-1-YL)(TETRAHYDROFURAN-2-YL)METHANONE. Grades: 95%. CAS No. 109351-34-0. Molecular formula: C19H25N5O4. Mole weight: 387.43. BOC Sciences 8
(R)-tert-butyl 6-cyano-5-hydroxy-3-oxohexanoate (R)-tert-butyl 6-cyano-5-hydroxy-3-oxohexanoate is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Synonyms: (5R)-6-Cyano-5-hydroxy-3-oxo-hexanoic Acid tert-Butyl Ester; R-tert-Butyl 6-Cyano-5-hydroxy-3-oxohexanoate. CAS No. 125988-01-4. Molecular formula: C11H17NO4. Mole weight: 227.26. BOC Sciences 8
(R)-Tetrahydrofuran-2-carbothioic S-acid An impurity of Faropenem. Faropenem is an oral penem, closely related to the carbapenem class that is used for the treatment of bacterial infections. Synonyms: (2R)?-tetrahydro-2-Furancarbothioic acid. Grades: > 95%. CAS No. 153165-72-1. Molecular formula: C5H8O2S. Mole weight: 132.18. BOC Sciences 8
(R)-Timolol Maleate The R-enantiomer of Timolol Maleate which is an adrenergic beta-receptor blocking agent and a Class II antiarrhythmic drug. Synonyms: Timolol Impurity A Maleate. Grades: > 95%. CAS No. 26839-77-0. Molecular formula: C13H24N4O3S.C4H4O4. Mole weight: 432.5. BOC Sciences 8
(R)-trans-Atracurium Besylate (R)-trans-Atracurium Besylate is an impurity of Cisatracurium, an enantiomer of a neuromuscular blocking agent. Synonyms: (1R,2S,1'R,2'S)-2,2'-{1,5-Pentanediylbis[oxy(3-oxo-3,1-propanediyl)]}bis[1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolinium] bisbenzenesulfonate. CAS No. 96946-46-2. Molecular formula: C65H82N2O18S2. Mole weight: 1243.48. BOC Sciences 8
(R)-Trolox (R)-Trolox is used in the synthesis of vitamin E analogs. Synonyms: (2R)-3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-carboxylic Acid; (+)-6-Hydroxy-2,5,7,8-tetramethyl-chroman-2-carboxylic Acid; (R)-(+)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic Acid. Grades: 98%. CAS No. 53101-49-8. Molecular formula: C14H18O4. Mole weight: 250.29. BOC Sciences 8
RU 58841 RU 58841 is a new non-steroidal antiandrogen which has potential for use in treating androgen-dependent skin disorders such as acne, hirsutism and androgen-dependent alopecia. Synonyms: RU-58841; RU58841; RU 58841; 4-(4,4-dimethyl-2,5-dioxo-3-(4-hydroxybutyl)-1-imidazolidinyl)-2-(trifluoromethyl)benzonitrile. CAS No. 154992-24-2. Molecular formula: C17H18F3N3O3. Mole weight: 369.34. BOC Sciences 8
RU-59063 RU-59063 is a nonsteroidal androgen or selective androgen receptor modulator (SARM). Synonyms: RU 59063; 4-(3-(4-Hydroxybutyl)-4,4-dimethyl-5-oxo-2-thioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile. CAS No. 155180-53-3. Molecular formula: C17H18F3N3O2S. Mole weight: 385.4. BOC Sciences 8
Rubitecan Rubitecan is a semisynthetic agent related to camptothecin with potent antitumor and antiviral properties. Rubitecan binds to and inhibits the enzyme topoisomerase I and induces protein-linked DNA single-strand breaks, thereby blocking DNA and RNA synthesis in dividing cells. This agent also prevents repair of reversible single-strand DNA breaks. Synonyms: RFS 2000; 9-Nitrocamptothecin; (4S)-4-Ethyl-4-hydroxy-10-nitro-1H-pyrano[3',4':6,7]indolizinol[1,2-b]quinoline-3,14(4H,12H)-dione; 9-NC; Orathecin; 9-nitro-20(S)-camptothecin; Camptogen; (S)-4-Ethyl-4-hydroxy-10-nitro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; 9-nitro-CPT; Nitrocamptothecin. Grades: ≥98%. CAS No. 91421-42-0. Molecular formula: C20H15N3O6. Mole weight: 393.35. BOC Sciences 8
Ruboxistaurin HCl Ruboxistaurin, also called as LY 333531, initially developed for the treatment of diabetic retinopathy, inhibits isolated enzymes PKCβI and PKCβII with a half-maximal inhibitory constant of 4.5 and 5.9 nM, respectively. The half-life of ruboxistaurin, which can be orally administered, is approximately 9h and that of its metabolite 16h, therefore allowing once-daily dosing. Based on data from clinicalTrials.gov, Children's Hospital Medical Center, Cincinnati plan a phase I/II trial of the effect of ruboxistaurin for its safety, tolerability, and effectiveness in treating adult patients with heart failure on June 9, 2016. Uses: Enzyme inhibitors. Synonyms: Ruboxistaurin Hydrochloride; LY-333531 hydrochloride; Ruboxistaurin (hydrochloride); 169939-93-9; LY 333531 hydrochloride; LY333531 hydrochloride; Ruboxistaurin-d6 Hydrochloride; 169939-94-0 (base). Grades: > 95%. CAS No. 169939-93-9. Molecular formula: C28H28N4O3.HCl. Mole weight: 505.01. BOC Sciences 8
Ruxolitinib phosphate Ruxolitinib phosphate is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM, >130-fold selectivity for JAK1/2 versus JAK3. Synonyms: INCB018424 phosphate; INCB 018424 phosphate; INCB-018424 phosphate. Grades: >98%. CAS No. 1092939-17-7. Molecular formula: C17H21N6O4P. Mole weight: 404.36. BOC Sciences 8
(R)-(-)-VAPOL hydrogenphosphate (R)-(-)-VAPOL hydrogenphosphate is a chiral phosphoric acid catalyst for a variety of enantioselective transformations, especially for carbon-carbon and carbon-heteroatom bond-forming reactions. Synonyms: (S)-VAPOL hydrogenphosphate; (8aR)-18-Hydroxy-8,9-diphenyldiphenanthro[4,3-d:3',4'-f][1,3,2]dioxaphosphepine 18-oxide. Grades: 95%. CAS No. 871130-18-6. Molecular formula: C40H25O4P. Mole weight: 600.60. BOC Sciences 8
(R)-Viloxazine Hydrochloride The R-isomer of Viloxazine, a selective norepinephrine reuptake inhibitor (NRI) used as an antidepressant. Uses: The (r)-isomer of. Synonyms: Morpholine, 2-[(2-ethoxyphenoxy)methyl]-, hydrochloride, (R)-. CAS No. 56287-63-9. Molecular formula: C13H20ClNO3. Mole weight: 273.76. BOC Sciences 8
(S)-10-(1-aminocyclopropyl)-9-fluoro-3-methyl-2H-[1,4]oxazino[2,3,4-ij]quinolin-7(3H)-one hydrochloride (S)-10-(1-aminocyclopropyl)-9-fluoro-3-methyl-2H-[1,4]oxazino[2,3,4-ij]quinolin-7(3H)-one hydrochloride is an impurity of Pazufloxacin. Pazufloxacin is a fluoroquinolone antibiotic. Synonyms: Pazufloxacin Impurity 07. CAS No. 143457-45-8. Molecular formula: C15H16ClFN2O2. Mole weight: 310.75. BOC Sciences 8
(S)-10-(1-aminocyclopropyl)-9-fluoro-6-hydroxy-3-methyl-2H-[1,4]oxazino[2,3,4-ij]quinolin-7(3H)-one hydrochloride (S)-10-(1-aminocyclopropyl)-9-fluoro-6-hydroxy-3-methyl-2H-[1,4]oxazino[2,3,4-ij]quinolin-7(3H)-one hydrochloride is an impurity of Pazufloxacin. Pazufloxacin is a fluoroquinolone antibiotic. Synonyms: Pazufloxacin Impurity 06. CAS No. 171567-51-4. Molecular formula: C15H16ClFN2O3. Mole weight: 326.75. BOC Sciences 8
S107 S107 is a type 1 ryanodine receptor (RyR1) stabilizer that binds RyR1 and enhances the binding affinity of calstabin-1. S107 increased FKBP12 binding to RyR1 in SR vesicles in the presence of reduced glutathione and the NO-donor NOC12, with no effect in the presence of oxidized glutathione. Synonyms: 2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine hydrochloride; S107; S-107; S 107. CAS No. 927871-76-9. Molecular formula: C11H15NOS. Mole weight: 209.31. BOC Sciences 8
(S)-10-Monohydroxy-10,11-dihydro Carbamazepine O-β-D-Glucuronide Sodium Salt (S)-10-Monohydroxy-10,11-dihydro Carbamazepine O-β-D-Glucuronide Sodium Salt is a metabolite of Carbamazepine, which is an anticonvulsant medication used primarily in the treatment of epilepsy and neuropathic pain. Synonyms: (10S)-5-(Aminocarbonyl)-10,11-dihydro-5H-dibenz[b,f]azepin-10-yl β-D-Glucopyranosiduronic Acid Sodium Salt; (S)-5-(Aminocarbonyl)-10,11-dihydro-5H-dibenz[b,f]azepin-10-yl β-D-Glucopyranosiduronic Acid Sodium Salt; Eslicarbazepine Glucuronide Sodium Salt; Sodium (2S,3S,4S,5R,6R)-6-[[(5S)-11-carbamoyl-5,6-dihydrobenzo[b][1]benzazepin-5-yl]oxy]-3,4,5-trihydroxyoxane-2-carboxylate. Molecular formula: C21H21N2NaO8. Mole weight: 452.39. BOC Sciences 8
S-((1-(2,2-Dimethyl-5-oxo-1,3-dioxolan-4-yl)cyclopropyl)methyl) Ethanethioate S-((1-(2,2-Dimethyl-5-oxo-1,3-dioxolan-4-yl)cyclopropyl)methyl) Ethanethioate is an intermediate of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Synonyms: Ethanethioic acid, S-[[1-(2,2-dimethyl-5-oxo-1,3-dioxolan-4-yl)cyclopropyl]methyl] ester. Molecular formula: C11H16O4S. Mole weight: 244.31. BOC Sciences 8
(S)-1,2,3,4-Tetrahydro-1-naphthalenemethanol (S)-1,2,3,4-Tetrahydro-1-naphthalenemethanol is an intermediate in the synthesis of Palonosetron, which is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Synonyms: (S)-1,2,3,4-Tetrahydronaphthalene-1-methanol; (S)-(1,2,3,4-Tetrahydronaphthalen-1-yl)methanol; 1-Naphthalenemethanol, 1,2,3,4-tetrahydro-, (1S)-; Palonosetron Impurity 52. Grades: ≥95%. CAS No. 151831-52-6. Molecular formula: C11H14O. Mole weight: 162.23. BOC Sciences 8
(S)-1-Methylnicotinium Iodide (S)-1-Methylnicotinium Iodide is one of Nicotine metabolites, which is a potent parasympathomimetic stimulant. Uses: A metabolite of nicotine. Synonyms: (S)-1-Methyl-3-(1-methyl-2-pyrrolidinyl)pyridinium Iodide; NIM; 1-Methyl-nicotinium Iodide; 1-Methyl-3-[(2S)-1-methyl-2-pyrrolidinyl]-pyridinium Iodide; 1-Methyl-3-(1-methyl-2-pyrrolidinyl)pyridinium Iodide; N-Methylnicotinium Iodide; Nicotine N-Methiodide; Nicotine Isomethiodide. Grades: 95%. CAS No. 21446-46-8. Molecular formula: C11H17IN2. Mole weight: 304.17. BOC Sciences 8
(S)-2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)isoindoline-1,3-dione (S)-2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)isoindoline-1,3-dione is an impurity of Apremilast, which is an oral phosphodiesterase 4 inhibitor used for treating psoriatic arthritis. CAS No. 2077897-93-7. Molecular formula: C20H21NO6S. Mole weight: 403.45. BOC Sciences 8
(S)-2-((3-(4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)isoindoline-1,3-dione (S)-2-((3-(4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)isoindoline-1,3-dione is an impurity of Linezolid, an oxazolidinone antimicrobial that is used to treat infections against gram-positive bacteria, especially those that are drug-resistant. Linezolid works by inhibiting bacterial protein synthesis. Synonyms: Linezolid Impurity 31. CAS No. 556801-12-8. Molecular formula: C22H21N3O5. Mole weight: 407.42. BOC Sciences 8
(S) -2-acetamido-6- ( (1- (3-ethoxy-4-methoxyphenyl) -2- (methylsulfonyl) ethyl) carbamoyl) benzoic acid (S) -2-acetamido-6- ( (1- (3-ethoxy-4-methoxyphenyl) -2- (methylsulfonyl) ethyl) carbamoyl) benzoic acid is an impurity of Apremilast, which is an oral phosphodiesterase 4 inhibitor used for treating psoriatic arthritis. Synonyms: 2-Acetamido-6-{[ (1S) -1- (3-ethoxy-4-methoxyphenyl) -2- (methylsulfonyl) ethyl]carbamoyl}benzoic acid. CAS No. 1809170-71-5. Molecular formula: C22H26N2O8S. Mole weight: 478.52. BOC Sciences 8
(S)-2-((R)-2,5-dioxo-3-propylpyrrolidin-1-yl)butanamide Cas No. 2432911-31-2. BOC Sciences 8
(S)-(3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl methanesulfonate (S)-(3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl methanesulfonate is an impurity of Linezolid, an oxazolidinone antimicrobial that is used to treat infections against gram-positive bacteria, especially those that are drug-resistant. Linezolid works by inhibiting bacterial protein synthesis. Synonyms: Linezolid Impurity 28. CAS No. 2180621-71-8. Molecular formula: C15H19FN2O6S. Mole weight: 374.38. BOC Sciences 8
(S)-3-(3-fluoro-4-morpholinophenyl)-5-(hydroxymethyl)oxazolidin-2-one (S)-3-(3-fluoro-4-morpholinophenyl)-5-(hydroxymethyl)oxazolidin-2-one is an impurity of Linezolid, an oxazolidinone antimicrobial that is used to treat infections against gram-positive bacteria, especially those that are drug-resistant. Linezolid works by inhibiting bacterial protein synthesis. Synonyms: 2-Oxazolidinone, 3-[3-fluoro-4-(4-morpholinyl)phenyl]-5-(hydroxymethyl)-, (5S); Linezolid Impurity 24. CAS No. 2180529-06-8. Molecular formula: C14H17FN2O4. Mole weight: 296.29. BOC Sciences 8
(S)-3-(4-(5-bromo-2-chlorobenzyl)phenoxy)tetrahydrofuran (S)-3-(4-(5-bromo-2-chlorobenzyl)phenoxy)tetrahydrofuran is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: (3S) -3-[4-[ (5-Bromo-2-chlorophenyl) methyl]phenoxy]tetrahydrofuran; Empagliflozin Impurity I. CAS No. 915095-89-5. Molecular formula: C17H16BrClO2. Mole weight: 367.66. BOC Sciences 8
(S)-3-(4-Chlorophenyl)-4-hydroxybutyric Acid Sodium Salt (S)-3-(4-Chlorophenyl)-4-hydroxybutyric Acid Sodium Salt is a metabolite of Baclofen, which is a specific GABA-B receptor agonist with muscle relaxant effect. Synonyms: (S)-β-(p-Chlorophenyl)-γ-hydroxybutyric Acid Sodium Salt; (S)-4-Chloro-β-(hydroxymethyl)benzenepropanoic Acid Sodium Salt. Grades: 98%. CAS No. 1346617-13-7. Molecular formula: C10H10ClNaO3. Mole weight: 236.63. BOC Sciences 8
(S)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Synonyms: Ibrutinib impurity SYGIM. Grades: ≥95%. CAS No. 1642630-12-3. Molecular formula: C22H22N6O. Mole weight: 386.45. BOC Sciences 8
(S)-3',5'-Bis(trifluoromethyl)-1-phenethanol (S)-3',5'-Bis(trifluoromethyl)-1-phenethanol is an intermediate of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Uses: Aprepitant intermediate. Synonyms: (αS)-α-Methyl-3,5-bis(trifluoromethyl)benzenemethanol; (S)-3,5-Bis(trifluoromethyl) Phenethyl Alcohol; (S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol; (S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethan-1-ol; (1S)-(-)-1-[3,5-Bis(trifluoromethyl)phenyl]ethan-1-ol; Benzenemethanol, α-methyl-3,5-bis(trifluoromethyl)-, (αS)-. Grades: ≥95%. CAS No. 225920-05-8. Molecular formula: C10H8F6O. Mole weight: 258.16. BOC Sciences 8
S38093 HCl S38093 HCl is a histamine H3 antagonist/inverse agonist. Synonyms: S38093 Hydrochloride; S 38093 Hydrochloride; S-38093 Hydrochloride; S-38093 HCl; S 38093 HCl; S38093 HCl; BCP29143; BCP 29143; BCP-29143; 4-[3-(3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl)propoxy]benzamide hydrochloride. CAS No. 1222097-72-4. Molecular formula: C17H25ClN2O2. Mole weight: 324.849. BOC Sciences 8
(S) -3-acetamido-2- ( (1- (3-ethoxy-4-methoxyphenyl) -2- (methylsulfonyl) ethyl) carbamoyl) benzoic acid (S) -3-acetamido-2- ( (1- (3-ethoxy-4-methoxyphenyl) -2- (methylsulfonyl) ethyl) carbamoyl) benzoic acid is an impurity of Apremilast, which is an oral phosphodiesterase 4 inhibitor used for treating psoriatic arthritis. Synonyms: 3-Acetamido-2-{[ (1S) -1- (3-ethoxy-4-methoxyphenyl) -2- (methylsulfonyl) ethyl]carbamoyl}benzoic acid. CAS No. 2096492-41-8. Molecular formula: C22H26N2O8S. Mole weight: 478.52. BOC Sciences 8
(S)-3-(bromomethyl)hexanoic acid Cas No. 2101641-92-1. BOC Sciences 8
(S)-3-chloro-N-((2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)thiophene-2-carboxamide An impurity of Rivaroxaban. Rivaroxaban inhibits both free Factor Xa and Factor Xa bound in the prothrombinase complex. It is a highly selective direct Factor Xa inhibitor with oral bioavailability and rapid onset of action. Synonyms: 2-Thiophenecarboxamide, 3-chloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-; Rivaroxaban Impurity 21. CAS No. 1855920-54-5. Molecular formula: C19H18ClN3O5S. Mole weight: 435.88. BOC Sciences 8
(S)-3-(dimethylamino)-1-(thiophen-2-yl)propan-1-ol (S)-3-(dimethylamino)-1-(thiophen-2-yl)propan-1-ol is an impurity of Duloxetine, an antidepressant medication used to treat major depressive disorder. Synonyms: (S)-1-β-Hydroxy-1-(2-thienyl)-3-dimethylaminopropane; (S)-N,N-Dimethyl-3-(2-thienyl)-3-hydroxypropanamine; 2-Thiophenemethanol, α-[2-(dimethylamino)ethyl]-, (αS)-; (αS)-α-[2-(Dimethylamino)ethyl]-2-thiophenemethanol; 2-Thiophenemethanol, α-[2-(dimethylamino)ethyl]-, (S)-; (1S)-3-(Dimethylamino)-1-(2-thienyl)-1-propanol; (1S)-3-(Dimethylamino)-1-(thiophen-2-yl)propan-1-ol; (S)-(-)-3-(Dimethylamino)-1-(thiophen-2-yl)propan-1-ol; (S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)propanamine; (S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)propylamine; (S)-3-(Dimethylamino)-1-(2-thienyl)-1-propanol; (S)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)-1-propylamine; (S)-α-[2-(Dimethylamino)ethyl]-2-thiophenemethanol. Grades: ≥95%. CAS No. 132335-44-5. Molecular formula: C9H15NOS. Mole weight: 185.29. BOC Sciences 8
(S)-3-(dimethylamino)-1-(thiophen-3-yl)propan-1-ol (S)-3-(dimethylamino)-1-(thiophen-3-yl)propan-1-ol is an impurity of Duloxetine, an antidepressant medication used to treat major depressive disorder. Synonyms: rac-alpha-[2-(Dimethylamino)ethyl]-3-thiophenemethanol. CAS No. 1384080-56-1. Molecular formula: C9H15NOS. Mole weight: 185.29. BOC Sciences 8
(S)-(3R,4R,5S,6R)-3,4-Dihydroxy-6-(hydroxymethyl)-5-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl 2,2,5,5-tetramethylthiazolidine-4-carboxylates BOC Sciences 8

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