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| Product | Description | |
|---|---|---|
| (S)-4-(4-((3-amino-2-hydroxypropyl)amino)phenyl)morpholin-3-one | An impurity of Rivaroxaban. Rivaroxaban inhibits both free Factor Xa and Factor Xa bound in the prothrombinase complex. It is a highly selective direct Factor Xa inhibitor with oral bioavailability and rapid onset of action. Synonyms: 4-[4-[[(2S)-3-Amino-2-hydroxypropyl]amino]phenyl]-3-morpholinone; Rivaroxaban Impurity 20; Rivaroxaban Impurity 41. Grades: 98% by HPLC. CAS No. 1403383-56-1. Molecular formula: C13H19N3O3. Mole weight: 265.31. |  |
| (S)-(-)-4-Amino-2-hydroxybutyric AcidAmikacin EP Impurity I | (S)-(-)-4-Amino-2-hydroxybutyric acid is an analogue of γ-aminobutyric acid (GABA) that exhibits potential inhibitory activity on GABA binding and uptake by brain. Synonyms: (2S)-4-Amino-2-hydroxybutanoic Acid; (S)-4-Amino-2-hydroxybutanoic Acid; (S)-4-Amino-2-hydroxybutyric Acid; 4-Amino-(2S)-hydroxybutyric Acid; L-(-)-4-Amino-2-hydroxybutyric Acid; L-(-)-γ-Amino-α-hydroxybutyric Acid; L-4-Amino-2-hydroxybutyric Acid; L-γ-Amino-α-hydroxybutyric Acid; (S)-(-)-4-Amino-2-hydroxybutyric Acid. Grades: 95%. CAS No. 40371-51-5. Molecular formula: C4H9NO3. Mole weight: 119.12. | |
| (S)-4-chloro-N-((2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)thiophene-2-carboxamide | An impurity of Rivaroxaban. Rivaroxaban inhibits both free Factor Xa and Factor Xa bound in the prothrombinase complex. It is a highly selective direct Factor Xa inhibitor with oral bioavailability and rapid onset of action. Synonyms: Rivaroxaban Impurity 22. CAS No. 1350288-77-5. Molecular formula: C19H18ClN3O5S. Mole weight: 435.88. | |
| (S)-4-propyldihydrofuran-2(3H)-one | Cas No. 63095-60-3. | |
| (S)-5-(1-(2-chlorophenyl)-2-methoxy-2-oxoethyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine-2-sulfonic acid | (S)-5-(1-(2-chlorophenyl)-2-methoxy-2-oxoethyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine-2-sulfonic acid is an impurity of Clopidogrel, an antithrombotic agent. Synonyms: Clopidogrel Impurity 13. CAS No. 2173294-69-2. Molecular formula: C15H14ClNO2S. Mole weight: 307.80. | |
| (S)-(-)-5-[(2-Acetoxypropanoyl)amino]-2,4,6-triiodoisophthalic Acid | (S)-(-)-5-[(2-Acetoxypropanoyl)amino]-2,4,6-triiodoisophthalic Acid is an intermediate of Iopamidol, which is a nonionic radiocontrast medium, used as a diagnostic aid (radiopaque medium). Synonyms: (S)-5-(2-Acetoxypropanamido)-2,4,6-triiodoisophthalic acid; 5-[[(2S)-2-(Acetyloxy)-1-oxopropyl]amino]-2,4,6-triiodo-1,3-benzendicarboxylic Acid; 5-{[(2S)-2-Acetoxypropanoyl]amino}-2,4,6-triiodoisophthalic acid; 1,3-Benzenedicarboxylic acid, 5-[[(2S)-2-(acetyloxy)-1-oxopropyl]amino]-2,4,6-triiodo-. CAS No. 1416451-25-6. Molecular formula: C13H10I3NO7. Mole weight: 672.93. | |
| (S)-(5-bromo-2-chlorophenyl)(4-((tetrahydrofuran-3-yl)oxy)phenyl)methanone | (S)-(5-bromo-2-chlorophenyl)(4-((tetrahydrofuran-3-yl)oxy)phenyl)methanone is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: (5-Bromo-2-chlorophenyl){4-[(3S)-tetrahydro-3-furanyloxy]phenyl}methanone. CAS No. 915095-84-0. Molecular formula: C17H14BrClO3. Mole weight: 381.65. | |
| (S)-5-chloro-N-(3-(5-chlorothiophene-2-carboxamido)-2-hydroxypropyl)-N-(4-(3-oxomorpholino)phenyl)thiophene-2-carboxamide | An impurity of Rivaroxaban. Rivaroxaban inhibits both free Factor Xa and Factor Xa bound in the prothrombinase complex. It is a highly selective direct Factor Xa inhibitor with oral bioavailability and rapid onset of action. Synonyms: Rivaroxaban Impurity 12. CAS No. 2204368-63-6. Molecular formula: C23H21Cl2N3O5S2. Mole weight: 554.47. | |
| S-(5-Mercapto-2-nitrobenzoic Acid)-D-penicillamine Disulfide | S-(5-Mercapto-2-nitrobenzoic Acid)-D-penicillamine Disulfide is an impurity of D-Penicillamine, which is a penicillin metabolite used in the treatment of Wilson's disease, Cystinuria, Scleroderma and arsenic poisoning. Synonyms: 5-{[(1S)-1-Amino-1-carboxy-2-methyl-2-propanyl]disulfanyl}-2-nitrobenzoic acid; Benzoic acid, 5-[[(2S)-2-amino-2-carboxy-1,1-dimethylethyl]dithio]-2-nitro-. Molecular formula: C12H14N2O6S2. Mole weight: 346.38. | |
| (S)-(5-Methoxy-1,3-oxathiolan-2-yl)methanol | (S)-(5-Methoxy-1,3-oxathiolan-2-yl)methanol is an intermediate of Lamivudine, a potent nucleoside reverse transcriptase inhibitor and antiviral agent. Lamivudine has also been used for treatment of chronic hepatitis B. Synonyms: 1,3-Oxathiolane-2-methanol, 5-methoxy-, (2S)-. Molecular formula: C5H10O3S. Mole weight: 150.20. | |
| (s)-6-amino-5-(4-amino-1,3-dioxoisoindolin-2-yl)-6-oxohexanoic acid | (s)-6-amino-5-(4-amino-1,3-dioxoisoindolin-2-yl)-6-oxohexanoic acid is an impurity of Pomalidomide, a thalidomide derivative with antitumor effects. CAS No. 918314-44-0. Molecular formula: C14H15N3O5. Mole weight: 305.29. | |
| Sacubitril | Sacubitril, also known as AHU377 or LCZ696, is an angiotensin receptor neprilysin inhibitor being studied for use in combination with valsartan for heart failure. Sacubitril is a prodrug that is activated to LBQ657 by de-ethylation via esterases. LBQ657 inhibits the enzyme neprilysin, which is responsible for the degradation of atrial and brain natriuretic peptide, two blood pressure lowering peptides that work mainly by reducing blood volume. Synonyms: Sacubitril; AHU 377; AHU377. Grades: >98%. CAS No. 149709-62-6. Molecular formula: C24H29NO5. Mole weight: 411.49. | |
| Sacubitril-(2S, 4S)-Isomer | Sacubitril-(2S, 4S)-isomer.Sacubitril is a prodrug neprilysin inhibitor used in combination with valsartan to reduce the risk of cardiovascular events in patients with chronic heart failure (NYHA Class II-IV) and reduced ejection fraction. Synonyms: (2S,4S)-Sacubitril; 149709-63-7; 4-(((2S,4S)-1-([1,1'-Biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoic acid; 4-[[(2S,4S)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoic acid; [1,1'-Biphenyl]-4-pentanoic acid, gamma-[(3-carboxy-1-oxopropyl)amino]-alpha-methyl-, alpha-ethyl ester, (alphaS,gammaS)-; LCZ 696 Impurity C; SCHEMBL18059568; DTXSID901127620; AKOS030528363; AS-80403; HY-78841; CS-0009335; 3-{[(2S,4S)-1-{[1,1'-biphenyl]-4-yl}-5-ethoxy-4-methyl-5-oxopentan-2-yl]carbamoyl}propanoic acid; 4-(((2S,4S)-1-([1,1'-Biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoicacid; alpha-Ethyl (alphaS,gammaS)-gamma-[(3-carboxy-1-oxopropyl)amino]-alpha-methyl[1,1'-biphenyl]-4-pentanoate. Grades: > 95%. CAS No. 149709-63-7. Molecular formula: C24H29NO5. Mole weight: 411.5. | |
| Sacubitril Enantiomer | Sacubitril enantiomer.Sacubitril is a prodrug neprilysin inhibitor used in combination with valsartan to reduce the risk of cardiovascular events in patients with chronic heart failure (NYHA Class II-IV) and reduced ejection fraction. Synonyms: 2R,4S-Sacubitril; (2R,4S)-5-(Biphenyl-4-yl)-4-[(3-carboxypropionyl)amino]-2-methylpentanoic acid ethyl ester; 4-[[(2R,4S)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoic acid; (2S,4R)-Sacubitril; SCHEMBL22420467; CS-M3545; AKOS030528367; HY-78847; MS-27102; PD100765; L10003; EN300-6474615; A854860; [1,1'-Biphenyl]-4-pentanoic acid, |A-[(3-carboxy-1-oxopropyl)amino]-|A-methyl-, 4-ethyl ester, (|AS,|AR)-; 3-{[(2R,4S)-1-{[1,1'-biphenyl]-4-yl}-5-ethoxy-4-methyl-5-oxopentan-2-yl]carbamoyl}propanoic acid; 4-(((2R,4S)-1-([1,1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoic acid; (alphaS,gammaR)-gamma-[(3-Carboxy-1-oxopropyl)amino]-alpha-methyl-[1,1'-biphenyl]-4-pentanoic acid 4-ethyl ester. Grades: > 95%. CAS No. 761373-05-1. Molecular formula: C24H29NO5. Mole weight: 411.5. | |
| Sacubitril Impurity 3 | An impurity of sacubitril. Sacubitril is an antihypertensive drug used in combination with valsartan. Synonyms: (3S,5S)-5-biphenyl-4-ylmethyl-3-methylpyrrolidin-2-one; (3S,5S)-5-[(Biphenyl-4-yl)methyl]-3-methylpyrrolidin-2-one. Grades: > 95%. CAS No. 1038925-00-6. Molecular formula: C18H19NO. Mole weight: 265.36. | |
| Sacubitril Impurity 4 | Sacubitrilat is one of the impurities of Sacubitril which has been found to be an endopeptidase inhibitor and be effective in the treatment of hypertension and heart failure. Synonyms: LBQ-657; LBQ 657; LBQ657; Sacubitrilat; UNII-SPI5PBF81S; LBQ657; CHEMBL417007; (2R,4S)-4-(3-carboxypropanoylamino)-2-methyl-5-(4-phenylphenyl)pentanoic acid. Grades: 98%. CAS No. 149709-44-4. Molecular formula: C22H25NO5. Mole weight: 383.44. | |
| Sacubitril Impurity 5 | An impurity of sacubitril. Sacubitril is an antihypertensive drug used in combination with valsartan. Synonyms: (αR,?γR)?-γ-[[(1,?1-Dimethylethoxy)?carbonyl]?amino]?-α-methyl-[1,?1'-biphenyl]?-4-pentanoic Acid. Grades: > 95%. CAS No. 1012341-56-8. Molecular formula: C23H29NO4. Mole weight: 383.49. | |
| Sacubitril Impurity 6 | An impurity of sacubitril. Sacubitril is an antihypertensive drug used in combination with valsartan. Synonyms: (αS,?γR)?-γ-[[(1,?1-Dimethylethoxy)?carbonyl]?amino]?-α-methyl-[1,?1'-biphenyl]?-4-pentanoic Acid. Grades: > 95%. CAS No. 1012341-54-6. Molecular formula: C23H29NO4. Mole weight: 383.49. | |
| Sacubitril Impurity 7 | An impurity of sacubitril. Sacubitril is an antihypertensive drug used in combination with valsartan. Synonyms: (αS,?γS)?-γ-[[(1,?1-Dimethylethoxy)?carbonyl]?amino]?-α-methyl-[1,?1'-biphenyl]?-4-pentanoic Acid. Grades: > 95%. CAS No. 1012341-52-4. Molecular formula: C23H29NO4. Mole weight: 383.49. | |
| Sacubitril N-Boc Ester | Sacubitril N-Boc Ester is an impurity of Sacubitril, an endopeptidase inhibitor that is effective in the treatment of hypertension and heart failure. Synonyms: Ethyl (2R, 4S) -5- (4-biphenylyl) -2-methyl-4- ({[ (2-methyl-2-propanyl) oxy]carbonyl}amino) pentanoate; (αR,γS)-γ-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-methyl-[1,1'-Biphenyl]-4-pentanoic Acid Ethyl Ester; [1,1'-Biphenyl]-4-pentanoic acid, gamma-[[(1,1-dimethylethoxy)carbonyl]amino]-alpha-methyl-, ethyl ester, (alphaR,gammaS)-; Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-4-[(tert-butoxycarbonyl)amino]-2-methylbutanoate. CAS No. 149709-60-4. Molecular formula: C25H33NO4. Mole weight: 411.53. | |
| Sacubitril sodium | Sacubitril, also known as AHU377, is a first-in-class medicine that contains a neprilysin (NEP) inhibitor (sacubitril) and an angiotensin II (Ang-II) receptor blocker (valsartan). Sacubitril is a prodrug that is activated to LBQ657 by de-ethylation via esterases. Synonyms: sodium 4-(((2S,4R)-1-([1,1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoate; Sacubitril sodium; AHU377; AHU 377; AHU-377; LCZ696. CAS No. 149690-05-1. Molecular formula: C24H29NO5.Na. Mole weight: 434.47. | |
| Safinamide Impurity 5 | An impurity of Safinamide, a selective monoamine oxidase B inhibitor, reducing degradation of dopamine. Synonyms: (S) -2- ( (4- ( (3-Fluorobenzyl) oxy) benzyl) amino) propanoic acid; (2S) -2-[[4-[ (3-fluorophenyl) methoxy]phenyl]methylamino]propanoic acid. Grades: >95%. CAS No. 1160513-60-9. Molecular formula: C17H18FNO3. Mole weight: 303.34. | |
| Safinamide Impurity 8 | An impurity of safinamide,safinamide is a selective monoamine oxidase B inhibitor, reducing degradation of dopamine. Synonyms: 4-[(3-Fluorophenyl)methoxy]benzenemethanol. Grades: > 95%. CAS No. 690969-16-5. Molecular formula: C14H13FO2. Mole weight: 232.26. | |
| Safinamide mesylate | Safinamide is a highly selective MAO-B inhibitor in rat brain mitochondria, with an IC50 of 98 nM. safinamide inhibits MAO-B in human brain with an IC50 of 9 nM. Synonyms: PNU-151774E; (S) -2- ( (4- ( (3-Fluorobenzyl) oxy) benzyl) amino) propanamide methanesulfonate. Grades: >98%. CAS No. 202825-46-5. Molecular formula: C17H19FN2O2.CH4O3S. Mole weight: 398.45. | |
| SAH-SOS1A | SAH-SOS1A is a cell-permeable, stabilized hydrocarbon-stapled alpha helical peptide that acts as a K-Ras/son of sevenless 1 (SOS1) interaction inhibitor. It binds within nucleotide binding pocket of wild-type and mutant K-Ras. CAS No. 1652561-87-9. Molecular formula: C100H159N27O28. Mole weight: 2187.53. | |
| Salicylcurcumin | Salicylcurcumin is a synthetic curcuminoid, a natural polyphenol family with anti-inflammatory and anticancer affects. Synonyms: Salicylcurcuminoid; 1,7-Bis(2-hydroxyphenyl)-5-hydroxy-1,4,6-heptatriene-3-one. Grades: ≥95%. CAS No. 1236545-54-2. Molecular formula: C19H16O4. Mole weight: 308.3. | |
| Salirasib | Salirasib is a salicylic acid derivative with potential antineoplastic activity. Salirasib dislodges all Ras isoforms from their membrane-anchoring sites, thereby preventing activation of RAS signaling cascades that mediated cell proliferation, differentiation, and senescence. RAS signaling is believed to be abnormally activated in one-third of human cancers, including cancers of the pancreas, colon, lung and breast. Synonyms: Salirasib; Farnesylthiosalicylic acid; S-Farnesylthiosalicylic acid; FTS. CAS No. 162520-00-5. Molecular formula: C22H30O2S. Mole weight: 358.54. | |
| Salmeterol Xinafoate | Salmeterol Xinafoate is a long-acting β2-adrenergic receptor agonist with anti-inflammatory effects, used in the treatment of asthma symptoms and chronic obstructive pulmonary disease (COPD) symptoms. Uses: Adrenergic beta-2 receptor agonists. Synonyms: GR-33343G; GR 33343G; GR33343G. Grades: >98%. CAS No. 94749-08-3. Molecular formula: C36H45NO7. Mole weight: 603.75. | |
| (S)-Alogliptin Benzoate Salt | (S)-Alogliptin Benzoate Salt is an impurity of alogliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor in the class of oral antidiabetic drugs. Synonyms: 2-[[6-[(3S)-3-Amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile Benzoate; (S)-2-((6-(3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile benzoate. CAS No. 1638544-64-5. Molecular formula: C25H27N5O4. Mole weight: 461.51. | |
| (S)-α-[3-[2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-4-methoxy-2-carboxylatebenzenepropanol Methyl Ester | (S)-α-[3-[2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-4-methoxy-2-carboxylatebenzenepropanol Methyl Ester is an intermediate in the production of Montelukast, which is a leukotriene receptor antagonist indicated for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. Synonyms: methyl (S,E)-2-(3-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-hydroxypropyl)-5-methoxybenzoate; Methyl 2-[(3S)-3-{3-[(E)-2-(7-chloro-2-quinolinyl)vinyl]phenyl}-3-hydroxypropyl]-5-methoxybenzoate; Benzoic acid, 2-[(3S)-3-[3-[(E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxypropyl]-5-methoxy-, methyl ester. Molecular formula: C29H26ClNO4. Mole weight: 487.97. | |
| (S)-α,α-Diphenylprolinol Hydrochloride | (S)-α,α-Diphenylprolinol Hydrochloride is the (S)-enantiomer of Diphenylprolinol, which is a norepinephrine-dopamine reuptake inhibitor used as a designer drug. Synonyms: (S)-α,α-Diphenyl-2-pyrrolidinemethanol Hydrochloride; (S)-D2PM Hydrochloride; (2S)-α,α-Diphenyl-2-pyrrolidinemethanol Hydrochloride; α,α-Diphenyl-L-prolinol Hydrochloride. Grades: ≥95%. CAS No. 148719-90-8. Molecular formula: C17H20ClNO. Mole weight: 289.80. | |
| Saquinavir Mesylate | Saquinavir is an HIV Protease Inhibitor used in antiretroviral therapy. It inhibits both HIV-1 and HIV-2 proteases. Studies have also looked at saquinavir as a possible anti-cancer agent. Uses: Hiv protease inhibitors. Synonyms: Invirase; Ro 31-8959/003. Grades: >98%. CAS No. 149845-06-7. Molecular formula: C39H54N6O8S. Mole weight: 766.95. | |
| SAR-20347 | Cas No. 1450881-55-6. | |
| SAR-405 | SAR-405 is a potent and selective inhibitor of phosphoinositide 3-kinase (PI3K) class III isoform Vps34 (IC50 = 1.2 nM, Kd=1.5 nM) without disrupting other PI3K isoforms and mTOR (IC50 > 10,000 nM). Concomitant inhibition of Vps34 and mTOR, with SAR405 and mTOR inhibitor everolimus, results in synergistic antiproliferative activity in renal tumor cell lines. Synonyms: SAR 405; SAR405; 4H-Pyrimido[1,?2-a]?pyrimidin-4-one, 9-[(5-chloro-3-pyridinyl)?methyl]?-6,?7,?8,?9-tetrahydro-2-[(3R)?-3-methyl-4-morpholinyl]?-8-(trifluoromethyl)?-, (8S)?-; (8S)-9-[(5-Chloro-3-pyridinyl)methyl]-6,7,8,9-tetrahydro-2-[(3R)-3-methyl-4-morpholinyl]-8-(trifluoromethyl)-4H-pyrimido[1,2-a]pyrimidin-4-one. CAS No. 1523406-39-4. Molecular formula: C19H21ClF3N5O2. Mole weight: 443.85. | |
| SAR7334 | SAR7334, a TRPC6 inhibitor, could be valuable in studying sorts of diseases related to TRPC. Uses: Sar7334 is a trpc6 inhibitor that could be valuable in studying sorts of diseases related to trpc. Synonyms: SAR7334; CPA1588; SAR 7334; CPA 1588; SAR-7334; CPA-1588; 4-(((1R,2R)-2-((R)-3-aminopiperidin-1-yl)-2,3-dihydro-1H-inden-1-yl)oxy)-3-chlorobenzonitrile; 1333207-63-8; 1333210-07-3; C21H22ClN3O. Grades: 98%. CAS No. 1333210-07-3. Molecular formula: C21H22ClN3O. Mole weight: 367.87. | |
| Saracatinib | Saracatinib, also known as AZD0530, is an orally available dual-specific inhibitor of Src and Abl with anti-invasive and anti-tumor activities. Src and Abl are protein tyrosine kinases that are overexpressed in chronic myeloid leukemia cells. Saracatinib binds to and inhibits these tyrosine kinases and their effects on cell motility, cell migration, adhesion, invasion, proliferation, differentiation, and survival. Specifically, Saracatinib inhibits Src kinase-mediated osteoclast bone resorption. Uses: Antineoplastic agents. Synonyms: AZD 0530; AZD-0530; AZD0530. Grades: >98%. CAS No. 379231-04-6. Molecular formula: C27H32ClN5O5. Mole weight: 542.03. | |
| Sarafotoxin S6c | Sarafotoxin S6c is a highly selective ETB endothelin receptor agonist (Ki = 0.29 and 28000 nM at ETB and ETA receptors, respectively). Uses: Vasoconstrictor agents. Synonyms: Sarafotoxin C; S6C; H-Cys-Thr-Cys-Asn-Asp-Met-Thr-Asp-Glu-Glu-Cys-Leu-Asn-Phe-Cys-His-Gln-Asp-Val-Ile-Trp-OH (Disulfide bridge: Cys1-Cys15, Cys3-Cys11); L-cysteinyl-L-threonyl-L-cysteinyl-L-asparagyl-L-alpha-aspartyl-L-methionyl-L-threonyl-L-alpha-aspartyl-L-alpha-glutamyl-L-alpha-glutamyl-L-cysteinyl-L-leucyl-L-asparagyl-L-phenylalanyl-L-cysteinyl-L-histidyl-L-glutaminyl-L-alpha-aspartyl-L-valyl-L-isoleucyl-L-tryptophan (1->15),(3->11)-bis(disulfide). Grades: ≥95% by HPLC. CAS No. 121695-87-2. Molecular formula: C103H147N27O37S5. Mole weight: 2515.75. | |
| Saralasin | Saralasin is a competitive and nonselective angiotensin II receptor antagonist. Uses: Angiotensin ii type 1 receptor blockers. Synonyms: (Sar1,Val5,Ala8)-Angiotensin II; Aralasin; Saralasinum. Grades: ≥97% by HPLC. CAS No. 34273-10-4. Molecular formula: C42H65N13O10. Mole weight: 912.04. | |
| S-(+)-Atomoxetine Hydrochloride | S-(+)-Atomoxetine Hydrochloride is an enatiomer of Atomoxetine, which is a selective norepinephrine (NE) reuptake inhibitor for the treatment of attention-deficit hyperactivity disorder (ADHD). Uses: The enatiomer of atomoxetine, a norepinephrine uptake blocker. Synonyms: (γS)-N-Methyl-γ-(2-methylphenoxy)benzenepropanamine Hydrochloride; (S)-(+)-Tomoxetine Hydrochloride; (S)-Tomoxetine Hydrochloride; LY 139602; Atomoxetine EP Impurity B; Ent S-(+)-atomoxetine hydrochloride. Grades: ≥95%. CAS No. 82857-39-4. Molecular formula: C17H22ClNO. Mole weight: 291.82. | |
| Savolitinib | Savolitinib is a tyrosine kinase inhibitor with potential anticancer activity. Synonyms: Volitinib; HMPL 504; HMPL0-504; HMPL504; AZD 6094; AZD 6094; AZD-6094; Savolitinib. Grades: >98%. CAS No. 1313725-88-0. Molecular formula: C17H15N9. Mole weight: 345.37. | |
| Saxagliptin monohydrate | Saxagliptin hydrate is a selective and reversible DPP4 inhibitor. It demonstrates greater specificity for DPP4 than for either the DPP8 or DPP9 enzymes. It reduces the degradation of the incretin hormone glucagon-like peptide-1, thereby enhancing its actions, and is associated with improved β-cell function and suppression of glucagon secretion. Synonyms: BMS-477118 hydrate; BMS 477118 hydrate; BMS477118 hydrate; Onglyza hydrate. Grades: >98%. CAS No. 945667-22-1. Molecular formula: C18H27N3O3. Mole weight: 333.43. | |
| SB1317 | SB1317 is a novel small molecule potent CDK/JAK2/FLT3 inhibitor. It dose-dependently inhibits signaling pathways downstream of CDKs, JAK2 and FLT3 in cancer cells with the main targets being CDKs. SB1317 is anti-proliferative in a broad range of tumor cell lines, inducing G1 cell cycle arrest and apoptosis. In vivo, SB1317 exhibits favorable pharmacokinetics after oral dosing in xenograft models and accumulates in tumor tissues, inducing an effective blockade of both CDK and STAT signaling. SB1317 induces tumor regression after oral dosing on both daily and intermittent schedules in a murine model of mutant-FLT3 leukemia (MV4-11) and prolongs survival in a disseminated AML model with wild-type FLT3 and JAK2 (HL-60). SB1317 is active in various models of leukemia and provide a rationale for the ongoing clinical evaluation of TG02 in patients with advanced leukemias. Synonyms: TG02; TG 02; TG-02; SB1317 (Double bond E); TG02 (Double bond E). Grades: ≥98%. CAS No. 1204918-72-8. Molecular formula: C23H24N4O. Mole weight: 372.46. | |
| SB239063 | SB239063 is a potent p38MAPK inhibitor. SB 239063 had an IC(50) of 44 nM for inhibition of recombinant purified human p38alpha. In lipopolysaccharide-stimulated human peripheral blood monocytes, SB 239063 inhibited interleukin-1 and tumor necrosis factor-alpha production. SB 239063 may be useful for the treatment of asthma and other inflammatory disorders. Uses: Protein kinase inhibitors. Synonyms: SB-239063; SB 239063. Grades: 0.98. CAS No. 193551-21-2. Molecular formula: C20H21FN4O2. Mole weight: 368.412. | |
| SB 277011A dihydrochloride | SB 277011A dihydrochloride is a selective and brain penetrating dopamine D3 receptor antagonist (pKi = 8.0, 6.0, 5.0 and <5.2 for D3, D2, 5-HT1D and 5-HT1B, respectively) with 100-fold selectivity over the hD2 receptor and over 66 other receptors. Synonyms: SB 277011A dihydrochloride; SB277011A dihydrochloride; SB-277011A dihydrochloride; N-[trans-4-[2-(6-Cyano-3,4-dihydro-2(1H)-isoquinolinyl)ethyl]cyclohexyl]-4-quinolinecarboxamide dihydrochloride. Grades: ≥98% by HPLC. CAS No. 1226917-67-4. Molecular formula: C28H30N4O.2HCl. Mole weight: 511.49. | |
| SB-3CT | SB-3CT is a potent matrix metalloproteinase MMP-2 and MMP-9 inhibitor. SB-3CT is a 2-[(arylsulfonyl)methyl]thiirane that achieves potent inhibition, by a thiirane-opening mechanism, of the MMP2 and MMP9 zinc metalloproteases. SB-3CT attenuates behavioral impairments and hippocampal loss after traumatic brain injury in rat. Matrix metalloproteinases (MMPs) are involved in a number of activities including angiogenesis and embryogenesis. Besides, gelatinases A (MMP-2) and B (MMP-9), are thought to facilitate tumor metastasis. Synonyms: MMP-2/MMP-9 Inhibitor IV; 2- ( (4-phenoxyphenylsulfonyl) methyl) thiirane; SB-3CT; SB3CT; SB3-CT; IN1250; IN 1250; IN-1250. Grades: 98%. CAS No. 292605-14-2. Molecular formula: C15H14O3S2. Mole weight: 306.394. | |
| SB705498 | SB705498 is a TRPV1 antagonist for hTRPV1, antagonizes capsaicin, acid, and heat activation of TRPV1 with IC50 of 3 nM, 0.1 nM and 6 nM, shows a degree of voltage dependence, exhibits >100-fold selectivity for TRPV1 over TRPM8. Synonyms: SB-705498; SB 705498; SB705498. Grades: >98%. CAS No. 501951-42-4. Molecular formula: C17H16BrF3N4O. Mole weight: 429.23. | |
| SB742457 | SB742457 is a selective 5-HT6 receptor antagonist with potential cognition, memory, and learning-enhancing effects.It was under development by GlaxoSmithKline for the treatment of Alzheimer's disease. Synonyms: SB742457; SB 742457; SB-742457; RVT-101; RVT 101; RVT101. intepirdine. GSK 742457; GSK742457; GSK-742457. Grades: >98%. CAS No. 607742-69-8. Molecular formula: C19H19N3O2S. Mole weight: 353.44. | |
| (S)-(+)-Clenbuterol | (S)-(+)-Clenbuterol is the (S)-Enantiomer of Clenbuterol and is used as a reagent in the synthesis of pyrazolopyridine derivatives as inhibitors of phosphodiesterase-4 (PDE-IV) and production of tumor necrosis factor-α (TNF-α). Uses: (s)-enantiomer of clenbuterol. substituted phenylethanolamine with β2 sympathomimetic activity. bronchodilator. Synonyms: (α S) -4-Amino-3, 5-dichloro-α -[[ (1, 1-dimethylethyl) amino]methyl]benzenemethanol; (+)-Clenbuterol; (S)-Clenbuterol. Grades: 98%. CAS No. 50499-60-0. Molecular formula: C12H18Cl2N2O. Mole weight: 277.19. | |
| (S)-Cloperastine | (S)-Cloperastine is used in the treatment of chronic non-productive cough. Synonyms: Levocloperastine; Privituss; 1-[2-[ (S) - (4-Chlorophenyl) phenylmethoxy]ethyl]piperidine. Grades: > 95%. CAS No. 132301-89-4. Molecular formula: C20H24ClNO. Mole weight: 329.86. | |
| (S)-Cloperastine Fendizoate | (S)-Cloperastine Fendizoate is the salt of (S)-Cloperastine, used in the treatment of chronic non-productive cough. Synonyms: Levocloperastine Fendizoate; 1-[2-[(4-Chlorophenyl)phenylmethoxy]ethyl]-piperidine (-)-, 2-[(6-Hydroxy[1,1'-biphenyl]-3-yl)carbonyl]benzoate; 2-[(6-Hydroxy[1,1'-biphenyl]-3-yl)carbonyl]benzoic Acid Compound With (-)-1-[2-[(4-Chlorophenyl)phenylmethoxy]eth. Grades: > 95%. CAS No. 220329-19-1. Molecular formula: C40H38ClNO5. Mole weight: 648.19. | |
| (S)-Cotinine N-Oxide | (S)-Cotinine N-Oxide is a major metabolite of Nicotine in humans. Synonyms: (5S)-1-Methyl-5-(1-oxido-3-pyridinyl)-2-pyrrolidinone; (-)-Cotinine N-oxide; 1-Methyl-5-(3-pyridinyl)-2-pyrrolidinone N-Oxide. Grades: > 95%. CAS No. 36508-80-2. Molecular formula: C10H12N2O2. Mole weight: 192.21. | |
| SD-06 | SD-06 is an inhibitor of p38α (IC50=170 nM). It is developed for the treatment of arthritis. Synonyms: SD 0006; SD-0006; SD0006; SD-06; SD-06; SD-06. CAS No. 271576-80-8. Molecular formula: C20H20ClN5O2. Mole weight: 397.86. | |
| S-Deoxo-3,17β-bis-(O-tetrahydro-2H-pyran-2-yl)-6-oxo-fulvestrant | S-Deoxo-3,17β-bis-(O-tetrahydro-2H-pyran-2-yl)-6-oxo-fulvestrant is an impurity of Fulvestrant, which is a selective estrogen receptor degrader (SERD) used to treat hormone receptor (HR)-positive metastatic breast cancer in postmenopausal women. Synonyms: 7-[9-[(4,4,5,5,5-Pentafluoropentyl)sulfenyl]nonyl]-3,17β-bis-(O-tetrahydro-2H-pyran-2-yl)estra-1,3,5(10)-triene-6-one; (17β)-7-{9-[(4,4,5,5,5-Pentafluoropentyl)sulfanyl]nonyl}-3,17-bis(tetrahydro-2H-pyran-2-yloxy)estra-1,3,5(10)-trien-6-one; Estra-1,3,5(10)-trien-6-one, 7-[9-[(4,4,5,5,5-pentafluoropentyl)thio]nonyl]-3,17-bis[(tetrahydro-2H-pyran-2-yl)oxy]-, (17β)-. Grades: ≥95%. CAS No. 862700-70-7. Molecular formula: C42H61F5O5S. Mole weight: 772.99. | |
| S-Deoxo-3,17-bis-(O-tetrahydro-2H-pyran-2-yl)-6-hydroxy-fulvestrant | S-Deoxo-3,17-bis-(O-tetrahydro-2H-pyran-2-yl)-6-hydroxy-fulvestrant is an impurity of Fulvestrant, which is a selective estrogen receptor degrader (SERD) used to treat hormone receptor (HR)-positive metastatic breast cancer in postmenopausal women. Synonyms: (7S,8R,9S,13S,14S,17S)-13-methyl-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-3,17-bis((tetrahydro-2H-pyran-2-yl)oxy)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-6-ol; 7-[9-[ (4, 4, 5, 5, 5-Pentafluoropentyl) sulfenyl]nonyl]estra-1, 3, 5 (10) -triene-6-ol-3, 17β -bis- (O-tetrahydro-2H-pyran-2-yl). Grades: >98%. Molecular formula: C42H63F5O5S. Mole weight: 775.00. | |
| S-Deoxo-3-Keto-17-Acetoxy Fulvestrant | S-Deoxo-3-Keto-17-Acetoxy Fulvestrant is an intermediate of Fulvestrant, which is a drug for breast cancer. Synonyms: (7α,17β)-17-(Acetyloxy)-7-[9-[(4,4,5,5,5-pentafluoropentyl)thio]nonyl]-estr-4-en-3-one; (7R,8R,9S,10R,13S,14S,17S)-13-Methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl Acetate. Grades: ≥95%. CAS No. 415927-29-6. Molecular formula: C34H51F5O3S. Mole weight: 634.82. | |
| S-Deoxo ?6-Fulvestrant | S-Deoxo ?6-Fulvestrant is an impurity of Fulvestrant, which is a drug for breast cancer. Synonyms: 7-[9-[ (4, 4, 5, 5, 5-Pentafluoropentyl) sulfenyl]nonyl]estra-1, 3, 5 (10) , 6-tetraene-3, 17β -diol; S-Deoxo Fulvestrant Impurity E. CAS No. 2170200-16-3. Molecular formula: C32H45F5O2S. Mole weight: 588.75. | |
| S-Deoxo-6-oxo-fulvestrant | S-Deoxo-6-oxo-fulvestrant is an impurity of Fulvestrant, which is a selective estrogen receptor degrader (SERD) used to treat hormone receptor (HR)-positive metastatic breast cancer in postmenopausal women. Synonyms: (7α,17β)-3,17-Dihydroxy-7-[9-[(4,4,5,5,5-pentafluoropentyl)thio]nonyl]-estra-1,3,5(10)-trien-6-one; Estra-1,3,5(10)-trien-6-one, 3,17-dihydroxy-7-[9-[(4,4,5,5,5-pentafluoropentyl)thio]nonyl]-, (7α,17β)-; (7α , 17β ) -3, 17-Dihydroxy-7-{9-[ (4, 4, 5, 5, 5-pentafluoropentyl) sulfanyl]nonyl}estra-1, 3, 5 (10) -trien-6-one. Grades: ≥95%. CAS No. 1107606-70-1. Molecular formula: C32H45F5O3S. Mole weight: 604.75. | |
| S-Deoxo Fulvestrant | S-Deoxo Fulvestrant is a derivative of Fulvestrant, an estrogen receptor antagonist used as a medication indicated for the treatment of hormone receptor (HR)-positive metastatic breast cancer in postmenopausal women. Synonyms: (7a,17b)-7-[9-[(4,4,5,5,5-Pentafluoropentyl)thio]nonyl]-estra-1,3,5(10)-triene-3,17-diol. Grades: 95%. CAS No. 153004-31-0. Molecular formula: C32H47F5O2S. Mole weight: 590.77. | |
| (S)-dimethyl 2-(4-(4-oxobutyl)benzamido)pentanedioate | (S)-dimethyl 2-(4-(4-oxobutyl)benzamido)pentanedioate is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: Pemetrexed Impurity 10. CAS No. 1081974-98-2. Molecular formula: C18H23NO6. Mole weight: 349.38. | |
| SDMA | An endogenous inhibitor of nitric oxide (NO) synthase activity. Synonyms: (2S) -2-amino-5-[ (N, N'-dimethylcarbamimidoyl) amino]pentanoic acid; guanidino-N(1),N(2)-dimethylarginine; N(G1),N(G2)-dimethylarginine; N,N'-dimethylarginine; NG,N'G-dimethyl-L-arginine; omega-N(G),N'(G)-dimethylarginine; sDMA arginine; symmetric dimethylarginine. CAS No. 30344-00-4. Molecular formula: C8H18N4O2. Mole weight: 202.25. | |
| S-Doxazosin | (S)-(+)-Doxazosin is an Isomer of Doxazosin Mesylate. Synonyms: (S)-1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl]-piperazine; 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[[(2S)-2,3-dihydro-1,4-benzodioxin-2-yl]carbonyl]piperazine. Grades: > 95%. CAS No. 104874-86-4. Molecular formula: C23H25N5O5. Mole weight: 451.48. | |
| (S,E)-4-broMo-N-(4-((3-chloro-4-fluorophenyl)aMino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide | Cas No. 1637254-93-3. | |
| (S,E)-4-(dimethylamino)-N-(4-((4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: Afatinib Impurity 18. Grades: ≥95%. CAS No. 2413212-25-4. Molecular formula: C24H26FN5O3. Mole weight: 451.50. | |
| (S,E)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-5-hydroxyhept-2-enoic acid calcium(II) | (S,E)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-5-hydroxyhept-2-enoic acid calcium(II) is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. CAS No. 1659317-57-3. Molecular formula: C66H64CaF2N4O8. Mole weight: 1119.33. | |
| Secalciferol | Secalciferol is a metabolite of Vitamin D, a possibly anti-inflammatory steroid which is involved in bone ossification. lt mediates calcium and phosphorus homeostasis and inhibits calcium channels in osteosarcoma cells via suppressing the effects of 1α, 25-dihydroxyvitamin D3 and testosterone. lt also can decrease the abundance of p53 and Pi-induced cytochrome c translocation. Uses: Bone density conservation agents. Synonyms: (24R)-24,25-Dihydroxyvitamin D3. Grades: >98%. CAS No. 55721-11-4. Molecular formula: C27H44O3. Mole weight: 416.64. | |
| Secnidazole Impurity B | An impurity of secnidazole. Secnidazole is a nitroimidazole anti-infective. Synonyms: 1-((2-Hydroxy-1-methyl)ethyl)-2-methyl-5-nitroimidazole; β,2-Dimethyl-5-nitro-1H-imidazole-1-ethanol. Grades: > 95%. CAS No. 56750-04-0. Molecular formula: C7H11N3O3. Mole weight: 185.18. | |
| seco-Lactam (Z)-Cefdinir Lactone | seco-Lactam (Z)-Cefdinir Lactone is one of Cefdinir derivatives. Cefdinir is a semi-synthetic, broad-spectrum antibiotic, used for soft tissue infections and respiratory tract infections. Synonyms: (Z)-2-(2-aminothiazol-4-yl)-2-(hydroxyimino)-N-((6R)-3-methyl-1,7-dioxo-1,4,5a,6-tetrahydro-3H,7H-azeto[2,1-b]furo[3,4-d][1,3]thiazin-6-yl)acetamide; 4-Thiazoleacetamide, 2-amino-α-(hydroxyimino)-N-[(6R)-1,4,5a,6-tetrahydro-3-methyl-1,7-dioxo-3H,7H-azeto[2,1-b]furo[3,4-d][1,3]thiazin-6-yl]-, (αZ)-. Molecular formula: C14H13N5O5S2. Mole weight: 395.41. | |
| Secretin Acetate | Secretin is a hormone secreted by the wall of the upper part of the small intestine (the duodenum). It is released in response to acid in the small intestine to regulate gastric acid secretion and pH levels in the duodenum. Synonyms: His-Ser-Asp-Gly-Thr-Phe-Thr- Ser-Glu-Leu-Ser-Arg-Leu-Arg- Glu-Gly-Ala-Arg-Leu-Gln-Arg- Leu-Leu-Gln-Gly-Leu-Val-NH2. Grades: 98%. CAS No. 10813-74-8. Molecular formula: C130H220N44O41. Mole weight: 3115.49. | |
| Seladelpar | Seladelpar is a selective peroxisome proliferator-activated receptor -δ receptor agonist. Phase II clinical trials for the treatment of Hyperlipidaemia, Hyperlipoproteinaemia type IIa and Primary biliary cirrhosis were on-going. Synonyms: MBX8025; RWJ800025; MBX 8025; RWJ 800025; MBX-8025; RWJ-800025; (R) -2- (4- ( (2-ethoxy-3- (4- (trifluoromethyl) phenoxy) propyl) thio) -2-methylphenoxy) acetic acid. Grades: 98%. CAS No. 851528-79-5. Molecular formula: C21H23F3O5S. Mole weight: 444.46. | |
| Seletalisib | Seletalisib is a selective Phosphatidylinositol 3 kinase delta inhibitor originated by UCB. It is an immunomodulator. Phaes I clinical trials for Plaque psoriasis, phaes II clinical trials for Sjogren's syndrome and phaes III clinical trials for Immunodeficiency disorders is on-going. Synonyms: UCB-5857; UCB 5857; UCB5857; (R)-3-(8-chloro-3-(2,2,2-trifluoro-1-(pyrido[3,2-d]pyrimidin-4-ylamino)ethyl)quinolin-2-yl)pyridine 1-oxide. Grades: 98%. CAS No. 1362850-20-1. Molecular formula: C23H14ClF3N6O. Mole weight: 482.85. | |
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