BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| ICMT-IN-45 | ICMT-IN-45 is an inhibitor of ICMT (IC50=0.132 μM). CAS No. 1313602-70-8. Molecular formula: C24H33NO. Mole weight: 351.52. |  |
| ICMT-IN-46 | ICMT-IN-46 is an inhibitor of ICMT (IC50=0.556 μM). CAS No. 1313602-71-9. Molecular formula: C25H35NO. Mole weight: 365.55. | |
| ICMT-IN-47 | ICMT-IN-47 is an inhibitor of ICMT (IC50=0.76 μM). CAS No. 1313602-72-0. Molecular formula: C25H35NO. Mole weight: 365.55. | |
| ICMT-IN-48 | ICMT-IN-48 is an inhibitor of ICMT. CAS No. 337486-54-1. Molecular formula: C30H37NO5. Mole weight: 491.62. | |
| ICMT-IN-49 | ICMT-IN-49 is an inhibitor of ICMT (IC50=0.12 μM). CAS No. 303728-92-9. Molecular formula: C27H31NO3. Mole weight: 417.54. | |
| ICMT-IN-5 | ICMT-IN-5 is an inhibitor of ICMT (IC50=0.3 μM). CAS No. 1313602-92-4. Molecular formula: C22H28FNO. Mole weight: 341.46. | |
| ICMT-IN-50 | ICMT-IN-50 is an inhibitor of ICMT (IC50=0.31 μM). CAS No. 371940-21-5. Molecular formula: C27H31NO3. Mole weight: 417.54. | |
| ICMT-IN-51 | ICMT-IN-51 is an inhibitor of ICMT (IC50=0.55 μM). CAS No. 1313602-89-9. Molecular formula: C21H26FNO. Mole weight: 327.44. | |
| ICMT-IN-52 | ICMT-IN-52 is an inhibitor of ICMT (IC50=0.052 μM). CAS No. 1313602-90-2. Molecular formula: C21H26FNO. Mole weight: 327.44. | |
| ICMT-IN-53 | ICMT-IN-53 is an inhibitor of ICMT (IC50=0.96 μM). It has PAMPA permeability and antiproliferative activity. CAS No. 1443253-17-5. Molecular formula: C26H36FN3. Mole weight: 409.58. | |
| ICMT-IN-54 | ICMT-IN-54, an adamantyl analogue, is an ICMT inhibitor (IC50=12.4 μM). Synonyms: (R)-2-[(adamantane-1-carbonyl)-amino]-3-(3,7,11-trimethyl-dodeca-2,6,10-trienylsulfanyl)-propionic acid. CAS No. 908856-14-4. Molecular formula: C29H45NO3S. Mole weight: 487.74. | |
| ICMT-IN-55 | ICMT-IN-55 is an ICMT inhibitor with IC50=90 nM. CAS No. 1313602-77-5. Molecular formula: C22H26F3NO2. Mole weight: 393.44. | |
| ICMT-IN-6 | ICMT-IN-6 is an inhibitor of ICMT (IC50=0.09 μM). CAS No. 1313602-75-3. Molecular formula: C23H31NO2. Mole weight: 353.50. | |
| ICMT-IN-7 | ICMT-IN-7 is an inhibitor of ICMT (IC50=0.015 μM). CAS No. 1313603-21-2. Molecular formula: C23H31NO. Mole weight: 337.50. | |
| ICMT-IN-8 | ICMT-IN-8 is an inhibitor of ICMT (IC50=0.652 μM). CAS No. 1313602-76-4. Molecular formula: C23H31NO3. Mole weight: 369.50. | |
| ICMT-IN-9 | ICMT-IN-9 is an inhibitor of ICMT (IC50=0.16 μM). CAS No. 1313602-93-5. Molecular formula: C22H28FNO2. Mole weight: 357.46. | |
| Icofungipen | Icofungipen, a cyclic β-amino acid, is the representative of a novel class of antifungals, active against Candida. Its in vivo efficacy indicates its potential for the oral treatment of yeast infections. Synonyms: (1R,2S)-2-amino-4-methylidenecyclopentane-1-carboxylic acid; Cyclopentanecarboxylic acid, 2-amino-4-methylene-, (1R,2S)- (9CI); Icofungipen; PLD 118; PLD118; PLD-118; BAY 10-8888; BAY 108888; BAY108888. Grade: 95%. CAS No. 198022-65-0. Molecular formula: C7H11NO2. Mole weight: 141.167. | |
| Icomethasone 21-Propionate | An impurity of Mometasone furoate, which is a topical corticosteroid used as an anti-inflammatory agent. Synonyms: 9-Chloro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-Propionate. CAS No. 107085-37-0. Molecular formula: C25H33ClO6. Mole weight: 464.98. | |
| Icopezil maleate | The maleate salt form of Icopezil, a benzoxazol derivative, has been found to be an acetylcholinesterase inhibitor and was once studied for the treatment of Alzheimer's disease. It has already been discontinued by Pfizer. Synonyms: CP 118954-11; CP-118,954-11. UNII-1P15W0SPEN; Icopezil maleate [USAN]; Icopezil maleate (USAN); 145815-98-1; CHEMBL329012; CP 118954-11. Grade: 98%. CAS No. 145815-98-1. Molecular formula: C27H29N3O6. Mole weight: 491.54. | |
| Icotinib | Icotinib Hydrochloride (BPI-2009H), or Icotinib, is a highly selective, first generation epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI). Synonyms: BPI-2009H. Grade: >98%. CAS No. 610798-31-7. Molecular formula: C22H21N3O4. Mole weight: 391.42. | |
| icrocaptide | icrocaptide. Synonyms: Icrocaptide. CAS No. 169543-49-1. Molecular formula: C21H40N8O5. | |
| iCRT 14 | iCRT 14 is a novel potent inhibitor of β-catenin-responsive transcription (CRT) that inhibits Wnt signaling. It is thought to directly influence the interaction between β-catenin and TCF4. It also induces marked G0/G1 cell cycle arrest in HCT-116 and HT29 cell lines. Synonyms: iCRT14; iCRT-14; iCRT 14; Wnt inhibitor; CHEMBL3589010; STK155594; 5-[[2,5-Dimethyl-1-(3-pyridinyl)-1H-pyrrol-3-yl]methylene]-3-phenyl-2,4-thiazolidinedione. Grade: >98%. CAS No. 677331-12-3. Molecular formula: C21H17N3O2S. Mole weight: 375.44. | |
| iCRT5 | iCRT5 is a Potent and cell-permeable β-catenin-responsive transcription (CRT) inhibitor (IC50 value of 18 nM for Wnt responsive STF16 luciferase). iCRT5 disrupts the interaction between β-catenin and TCF4, possibly by direct binding to β-catenin. Synonyms: iCRT5; iCRT-5; iCRT 5; 4-[5-(3,4-Dimethoxy-benzylidene)-4-oxo-2-thioxo-thiazolidin-3-yl]-butyric acid; 4-[(5Z)-5-[(3,4-dimethoxyphenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]butanoic acid; EN300-00774; AC1Q49FJ. Grade: 99%. CAS No. 18623-44-4. Molecular formula: C16H17NO5S2. Mole weight: 367.44. | |
| Icrucumab | Icrucumab is a human monoclonal antibody directed against vascular endothelial growth factor receptor-1 (VEGFR-1). Icrucumab inhibits ligand-dependent phosphorylation of VEGFR-1 and downstream signaling, making icrucumab an attractive candidate for antitumor activity. Synonyms: IMC-18F1. Grade: 95%. CAS No. 1024603-92-6. Molecular formula: C6514H10024N1756O2032S42. Mole weight: 146.8 kDa. | |
| ID-11014A | ID-11014A is a potent and selective agonist of GPR40 (free fatty acid receptor 1) that can increase insulin secretion and reduce glucose levels. Studies shows that it has a lower liver toxicity than TAK-785 and an improved glucose tolerance. Uses: The potential treatment of diabetes. Synonyms: ID 11014A. | |
| ID-8 | ID-8 is a DYRK inhibitor, and sustains embryonic stem cell self-renewal in long-term culture. Synonyms: ID-8; ID 8; ID8. Grade: >98%. CAS No. 147591-46-6. Molecular formula: C16H14N2O4. Mole weight: 298.29. | |
| Idarubicin-13C, d3 | Idarubicin-13C, d3 is a labelled Idarubicin. Idarubicin is an anthracycline drug of the antitumor antibiotic family used to treat leukemia. Grade: > 95%. Molecular formula: C25H24NO9[13C]D3. Mole weight: 501.51. | |
| Idarubicin-d4 | Idarubicin-d4 is a labelled Idarubicin. Idarubicin is an anthracycline drug of the antitumor antibiotic family used to treat leukemia. Grade: > 95%. Molecular formula: C26H23NO9D4. Mole weight: 501.53. | |
| Idarubicin Dioxolane Hydrochloride | Idarubicin Dioxolane Hydrochloride is a possible impurity of Idarubicin, which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor. It is also an analog of Daunorubicin. Synonyms: (7S,9S)-7-(((2R,4S,5S,6S)-4-Amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,9,11-trihydroxy-9-(2-methyl-1,3-dioxolan-2-yl)-7,8,9,10-tetrahydrotetracene-5,12-dione Hydrochloride. Molecular formula: C28H31NO10.HCl. Mole weight: 578.01. | |
| Idarubicin Hydrochloride | Idarubicin HCl is a hydrochloride salt form of Idarubicin which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells with IC50 of 3.3 ng/mL. Uses: Antibiotics, antineoplastic. Synonyms: (7S,9S)-9-Acetyl-7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-5,12-naphthacenedione Hydrochloride; 4-DMD HCl; 4-Demethoxydaunorubicin Hydrochloride; Idamycin; NSC 256439; Zavedos; (1S,3S)-3-Acetyl-3,5,12-trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside hydrochloride (1:1). Grade: >98%. CAS No. 57852-57-0. Molecular formula: C26H28ClNO9. Mole weight: 533.95. | |
| Idarubicin Impurity 2 | Idarubicin Impurity 2 is an impurity of Idarubicin, which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor. Molecular formula: C28H31NO10. Mole weight: 541.55. | |
| Idarubicin Impurity 4 | Idarubicin Impurity 4 is an impurity of Idarubicin, which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor. Synonyms: N-[(2S,3S,4S,6R)-6-[[(1S,3S)-3-acetyl-3,12-dihydroxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]-3-hydroxy-2-methyloxan-4-yl]-2,2,2-trifluoroacetamide; 5,12-Naphthacenedione, 9-acetyl-7,8,9,10-tetrahydro-6,9-dihydroxy-7-[[2,3,6-trideoxy-3-[(trifluoroacetyl)amino]-α-L-lyxo-hexopyranosyl]oxy]-, (7S-cis)-. CAS No. 85440-44-4. Molecular formula: C28H26F3NO9. Mole weight: 577.51. | |
| Idarubicin Isomer | Idarubicin Isomer is an impurity of Idarubicin, which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor. Synonyms: (1S,3S)-3-Acetyl-3,5,12-trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-β-L-lyxo-hexopyranoside; (7S-cis)-9-Acetyl-7-((3-amino-2,3,6-trideoxy-β-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,9,11-trihydroxy-5,12-naphthacenedione; 5,12-Naphthacenedione, 9-acetyl-7-[(3-amino-2,3,6-trideoxy-β-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-, (7S,9S)-; 4-Demethoxydaunorubicin, beta; 4-Demethoxy-7,9-di-epi-daunorubicin, beta; 7-O-β-Daunosaminyl-4-demethoxydaunomycinone; 5,12-Naphthacenedione, 9-acetyl-7-[(3-amino-2,3,6-trideoxy-β-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-, (7S-cis)-. Grade: ≥95%. CAS No. 58957-93-0. Molecular formula: C26H27NO9. Mole weight: 497.49. | |
| Idarubicin Isomer hydrochloride | Idarubicin Isomer hydrochloride is an impurity of Idarubicin, which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor. Synonyms: (7S,9S)-9-Acetyl-7-(((2S,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,9,11-trihydroxy-7,8,9,10-tetrahydrotetracene-5,12-dione hydrochloride; Idarubicin Impurity 6; (1S,3S)-3-Acetyl-3,5,12-trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-β-L-lyxo-hexopyranoside hydrochloride; (7S-cis)-9-Acetyl-7-((3-amino-2,3,6-trideoxy-β-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,9,11-trihydroxy-5,12-naphthacenedione hydrochloride; 5,12-Naphthacenedione, 9-acetyl-7-[(3-amino-2,3,6-trideoxy-β-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-, (7S,9S)-, hydrochloride (1:1); 7-O-β-Daunosaminyl-4-demethoxydaunomycinone hydrochloride; Daunomycinone, 7-O-β-daunosaminyl-4-demethoxy-, hydrochloride. CAS No. 60660-72-2. Molecular formula: C26H27NO9.HCl. Mole weight: 533.96. | |
| Idarubicinol | Idarubicinol is the alcohol analog of Idarubicin, which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor. It is also an analog of Daunorubicin. Synonyms: 5,12-Naphthacenedione, 7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-9-[(1S)-1-hydroxyethyl]-, (7S,9S)-; (7S,9S)-7-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-9-[(1S)-1-hydroxyethyl]-5,12-naphthacenedione; 5,12-Naphthacenedione, 7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-9-(1-hydroxyethyl)-, [7S-[7α,9α,9(R*)]]-; 13-Dihydroidarubicin; 4-Demethoxydaunorubicinol; Antibiotic FCE 22723. Grade: > 95%. CAS No. 86189-66-4. Molecular formula: C26H29NO9. Mole weight: 499.52. | |
| Idarubicinol-13C, d3 | Idarubicinol-13C, d3 is a labelled nalogue of Idarubicinol. Grade: > 95%. Molecular formula: C26H26NO9D3. Mole weight: 503.53. | |
| Idarubicinol-d4 | Idarubicinol-d4 is a labelled Idarubicinol. Synonyms: Idarubicinol-d4 (Mixture of Diastereomers); (7S,9S)-7-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-9-[(1R*)-1-hydroxyethyl]-5,12-naphthacenedione-d4; [7S-[7α,9α,9(R*)]]-7-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopy. Grade: > 95%. Molecular formula: C26H25NO9D4. Mole weight: 503.55. | |
| Idarubicinone | Idarubicinone is a derivative of Daunorubicin, which is an anthracycline antibiotic used in the treatment of acute myeloid and lymphocytic leukemia, with adverse reactions such as cardiotoxicity and bone marrow suppression. Synonyms: 4-demethoxy daunomycinone; (7S,9S)-9-acetyl-6,7,9,11-tetrahydroxy-7,8,9,10-tetrahydrotetracene-5,12-dione; 4-Demethoxydaunomycinone; Idarubicin aglycone; (+)-4-Demethoxydaunomycinone; 5,12-Naphthacenedione, 9-acetyl-7,8,9,10-tetrahydro-6,7,9,11-tetrahydroxy-, (7S-cis)-; (+)-Idarubicinone; (8S,10S)-7,8,9,10-Tetrahydro-6,8,10,11-tetrahydroxy-8-acetyl-5,12-naphthacenedione. Grade: ≥95%. CAS No. 60660-75-5. Molecular formula: C20H16O7. Mole weight: 368.34. | |
| Idasanutlin | Idasanutlin; also known as RG7388 and RO5503781, is a highly potent and selective MDM2 antagonist with potential anticancer activity. RG7388 binds to MDM2 blocking the interaction between the MDM2 protein and the transcriptional activation domain of the tumor suppressor protein p53. By preventing the MDM2-p53 interaction, p53 is not enzymatically degraded and the transcriptional activity of p53 is restored. This may lead to p53-mediated induction of tumor cell apoptosis. MDM2, a zinc finger nuclear phosphoprotein and negative regulator of the p53 pathway, is often overexpressed in cancer cells and has been implicated in cancer cell proliferation and survival. Uses: For research used only. Synonyms: RG7388; RG 7388; RG-7388; RO5503781; RO-5503781; RO 5503781. Grade: >98%. CAS No. 1229705-06-9. Molecular formula: C31H29Cl2F2N3O4. Mole weight: 616.487. | |
| Idazoxan | Idazoxan is an I2 imidazoline receptor agonist, I1 imidazoline receptor antagonist, and alpha2-adrenoceptor antagonist used in trials studying the basic science of molecular imaging, Alzheimer's disease, and major depressive disorder. Synonyms: 1H-Imidazole, 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-; 2-(2,3-Dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole; 2-Imidazoline, 2-(1,4-benzodioxan-2-yl)-; (±)-Idazoxan; dl-Idazoxan; Racemic idazoxan. Grade: 95%. CAS No. 79944-58-4. Molecular formula: C11H12N2O2. Mole weight: 204.23. | |
| Idazoxan hydrochloride | Idazoxan hydrochloride is the hydrochloride salt of idazoxan, which is an I2 imidazoline receptor agonist, I1 imidazoline receptor antagonist, as well as an alpha2-adrenoceptor antagonist. It is selective for α2- over α1-receptors. It is useful for the treatment of parkinsonian and schizophrenia. Synonyms: 1H-Imidazole, 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-, hydrochloride (1:1); 1H-Imidazole, 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-, monohydrochloride; (±)-Idazoxan monohydrochloride; 2-(2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole hydrochloride; RX 781094; RX 781094A. Grade: ≥98%. CAS No. 79944-56-2. Molecular formula: C11H13ClN2O2. Mole weight: 240.69. | |
| Idebenone-d6 | Idebenone-d6 is a labelled Idebenone. Idebenone is a synthetic analogue of coenzyme Q10. It is indicated for the treatment of Alzheimer's disease. Synonyms: 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione-d6. Grade: > 95%. Molecular formula: C19H24O5D6. Mole weight: 344.48. | |
| Idebenone-D-Glucuronide | Idebenone-D-Glucuronide is a compound used for studying neurodegenerative ailments, most notably Alzheimer's and Parkinson's. Grade: > 95%. Molecular formula: C25H38O11. Mole weight: 514.58. | |
| Idebenone Glucuronide | Idebenone Glucuronide is the glucuronoside conjugate of Idebenone, an ubiquinone derivative with protective effects against cerebral ischemia. Synonyms: 2-(10-Hydroxydecyl)-5,6-methoxy-3-methyl-2,5-cyclohexadiene-1,4-dione β-D-Glucopyranosiduronic Acid; 2,3-Dimethoxy-6-(10-hydroxydecyl)-5-methyl-1,4-benzoquinone β-D-Glucopyranosiduronic Acid; Avan Glucuronide; CV 2619 Glucuronide; Daruma Glucuronide; Mnesis Glucuronide; Idebenone β-D-Glucuronide. Molecular formula: C25H38O11. Mole weight: 514.56. | |
| Idebenone Glucuronide-13C,d3 | The isotope-labelled idebenone glucuronide is a glucuronide conjugate of idebenone. Idebenone is a ubiquinone derivative with protective effects on cerebral ischemia. Synonyms: 2-(10-Hydroxydecyl)-5,6-methoxy-3-methyl-2,5-cyclohexadiene-1,4-dione β-D-Glucopyranosiduronic Acid-13C,d3; 2,3-Dimethoxy-6-(10-hydroxydecyl)-5-methyl-1,4-benzoquinone β-D-Glucopyranosiduronic Acid-13C,d3; Avan Glucuronide-13C,d3; CV 2619 Glucuronide-13C,d3; Daruma Glucuronide-13C,d3; Mnesis Glucuronide-13C,d3. Molecular formula: C24[13C]H35D3O11. Mole weight: 518.57. | |
| Idebenone Sulfate | Idebenone Sulfate is a potent biomedical product used to study the progression of neurodegenerative disorders such as Alzheimer's and Parkinson's diseases. It exhibits antioxidant and neuroprotective properties. Synonyms: 10-(4,5-dimethoxy-2-methyl-3,6-dioxocyclohexa-1,4-dien-1-yl)decyl hydrogen sulfate; 319906-76-8. Grade: > 95%. CAS No. 319906-76-8. Molecular formula: C19H30O8S. Mole weight: 418.51. | |
| Idebenone Sulfate-13C,d3 Potassium Salt | Isotope labelled Idebenone Sulfate is an analogue of Idebenone. It is an ubiquinone derivative with protective effects against cerebral ischemia. Idebenone Sulfate can be used for skin protection and regenerative purposes. Synonyms: 2,3-Dimethoxy-5-methyl-6-[10-(sulfooxy)decyl]-2,5-cyclohexadiene-1,4-dione13C,d3 Potassium Salt. Molecular formula: C18[13C]H26D3KO8S. Mole weight: 460.6. | |
| Idelalisib | Idelalisib is a kinase inhibitor. In combination with rituximab, it was used for the treatment of relapsed or refractory chronic lymphocytic leukemia (CLL). Uses: The treatment of chronic lymphocytic leukemia (cll). Synonyms: Idelalisib; CAL101; CAL 101; CAL-101; GS1101; GS 1101; GS-1101, Idelalisib. Grade: > 95%. CAS No. 870281-82-6. Molecular formula: C22H18FN7O. Mole weight: 415.432. | |
| Idelalisib Metabolit | Idelalisib Metabolite is a metabolite of Idelalisib, a drug primarily employed in the treatment of chronic lymphocytic leukemia and follicular lymphoma. Synonyms: GS-563117. Grade: > 95%. Molecular formula: C22H18FN7O2. Mole weight: 431.43. | |
| Idelalisib Metabolit-d5 | Idelalisib Metabolit-d5. Grade: > 95%. Molecular formula: C22H13FN7O2D5. Mole weight: 436.46. | |
| Idelalisib N-Glucuronide | Idelalisib N-Glucuronide is an exclusive metabolite of Idelalisib, a prominent therapeutic agent for chronic lymphocytic leukemia (CLL), follicular lymphoma, and small lymphocytic lymphoma, exhibiting its efficacious function as a precise and strategic kinase inhibitor. Grade: > 95%. Molecular formula: C28H27FN7O7. Mole weight: 592.57. | |
| IDF-11774 | IDF-11774 is a hypoxia-inducible factor-1 (HIF-1) inhibitor. Study showed that IDF-11774 inhibited the accumulation of HIF-1α in vitro and in vivo in colorectal carcinoma HCT116 cells under hypoxic conditions, suppressing angiogenesis of cancer cells by reducing the expression of HIF-1 target genes. Synonyms: EX-A3002; 2-[4-(1-adamantyl)phenoxy]-1-(4-methylpiperazin-1-yl)ethanone. CAS No. 1429054-28-3. Molecular formula: C23H32N2O2. Mole weight: 368.51. | |
| IDFP | IDFP is an organophosphorus compound that acts as an irreversible inhibitor of MAGL and FAAH with IC50 values of 0.8 and 3 nM, respectively. Inhibition of MAGL and FAAH increases anandamide and 2-AG in the brain, resulting in increased cannabinoid signaling and typical cannabinoid behavioral effects in animal studies. Synonyms: Isopropyl Dodecylfluorophosphonate; 1-[fluoro(propan-2-yloxy)phosphoryl]dodecane. Grade: ≥98%. CAS No. 615250-02-7. Molecular formula: C15H32FO2P. Mole weight: 294.4. | |
| IDH1 Inhibitor 8 | IDH1 Inhibitor 8 is an isocitrate dehydrogenase 1 (IDH1) inhibitor that can be used in cancer research. Synonyms: AG-120 Racemate; AG-120 (racemic); Ivosidenib (racemic); 1-(4-Cyano-2-pyridinyl)-5-oxo-L-prolyl-2-(2-chlorophenyl)-N-(3,3-difluorocyclobutyl)-N2-(5-fluoro-3-pyridinyl)glycinamide. Grade: 98%. CAS No. 1448346-63-1. Molecular formula: C28H22ClF3N6O3. Mole weight: 582.97. | |
| IDH305 | IDH305 is a potent, selective and brain penetrant inhibitor of mutant isocitrate dehydrogenase 1 (IDH1; IC50s = 27, 28, and 6,140 nM for recombinant IDH1R132H, IDH1R132C, and wild-type IDH1, respectively). It suppresses mutant IDH1-dependent 2-HG production and cell proliferation, and exhibits antitumor activity in preclinical studies. Synonyms: (4R)-4-[(1S)-1-fluoroethyl]-3-[2-({(1S)-1-[4-methyl-2'-(trifluoromethyl)[3,4'-bipyridin]-6-yl]ethyl}amino)pyrimidin-4-yl]-1,3-oxazolidin-2-one. Grade: ≥98%. CAS No. 1628805-46-8. Molecular formula: C23H22F4N6O2. Mole weight: 490.45. | |
| IDN-1965 | IDN-1965 is a potent, broad-spectrum, irreversible caspase inhibitor. IDN-1965 is markedly effective at inhibiting Fas-mediated apoptosis by multiple routes of administration. The therapeutic potential of caspase inhibitors appears promising for the treatment of apoptosis-mediated liver injury based on potency and postinsult efficacy. Synonyms: IDN1965; IDN 1965; N-[(1,3-Dimethylindole-2-Carbonyl)Valinyl]-3-Amino-4-Oxo-5-Fluoropentanoic Acid; 3-((S)-2-(1,3-dimethyl-1H-indole-2-carboxamido)-3-methylbutanamido)-5-fluoro-4-oxopentanoic acid. Grade: 98%. CAS No. 204919-14-2. Molecular formula: C21H26FN3O5. Mole weight: 419.45. | |
| IDO1 and HDAC1 Inhibitor | IDO1 and HDAC1 Inhibitor is a dual inhibitor of IDO1 and HDAC1 with IC50s of 69.0 nM and 66.5 nM, respectively. Synonyms: N-(2-Aminophenyl)-N'-[2-({4-[N-(3-bromo-4-fluorophenyl)-N'-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}amino)ethyl]terephthalamide; 1,4-Benzenedicarboxamide, N1-(2-aminophenyl)-N4-[2-[[4-[(E)-[(3-bromo-4-fluorophenyl)amino](hydroxyimino)methyl]-1,2,5-oxadiazol-3-yl]amino]ethyl]-. CAS No. 2227044-16-6. Molecular formula: C25H22BrFN8O4. Mole weight: 597.40. | |
| IDO-IN-1 | An IDO inhibitor with IC50 of 59 nM, showing activity in Hela cell (IC50 = 12 nM). Synonyms: IDO-IN-1; IDO-IN1; IDO-IN 1. Grade: > 98%. CAS No. 914638-30-5. Molecular formula: C9H7BrFN5O2. Mole weight: 316.09. | |
| IDO-IN-13 | IDO-IN-13 is an IDO1 inhibitor with EC50 of 17 nM. Grade: 98% by HPLC. CAS No. 2291164-02-6. Molecular formula: C26H17F3N4O. Mole weight: 458.4. | |
| IDO-IN-2 | IDO-IN-2 is a potent inhibitor of IDO (indoleamine-(2,3)-dioxygenase) with IC50 of 3 nM. Synonyms: IDO inhibitor 1; 1-[2-[bis(2-methylpropyl)amino]-5-[2-(2H-tetrazol-5-yl)phenyl]phenyl]-3-(4-methylphenyl)urea. CAS No. 1668565-74-9. Molecular formula: C29H35N7O. Mole weight: 497.63. | |
| IDO-IN-3 | A potent IDO inhibitor. Synonyms: IDO-IN-3; IDO-IN3; IDO-IN 3. Grade: > 98%. CAS No. 2070018-30-1. Molecular formula: C11H12BrFN6O2. Mole weight: 359.15. | |
| IDO-IN-4 | A potent IDO1 inhibitor with IC50 of 8 nM in human IDO1/HEK293 cells. Synonyms: IDO-IN-4; IDO-IN4; IDO-IN 4.(1R,2S)-2-(4-(diisobutylamino)-3-(3-(p-tolyl)ureido)phenyl)cyclopropanecarboxylic acid. Grade: > 98%. CAS No. 1629125-65-0. Molecular formula: C26H35N3O3. Mole weight: 437.57. | |
| IDO-IN-5 | A potent human IDO inhibitor with IC50 of 1-10 μM. Synonyms: IDO-IN-5; IDO-IN5; IDO-IN 5.(1R,4r)-4-((R)-2-((R)-6-fluoro-5H-imidazo[5,1-a]isoindol-5-yl)-1-hydroxyethyl)cyclohexanol. Grade: > 98%. CAS No. 1402837-79-9. Molecular formula: C18H21FN2O2. Mole weight: 316.37. | |
| IDO-IN-6 | A potent human IDO inhibitor with IC50 of <1 μM. Synonyms: IDO-IN-6; IDO-IN6; IDO-IN 6.(1S,4r)-4-((S)-2-((S)-6-fluoro-5H-imidazo[5,1-a]isoindol-5-yl)-1-hydroxyethyl)cyclohexanol. Grade:> 98%. CAS No. 1402837-76-6. Molecular formula: C18H21FN2O2. Mole weight: 316.37. | |
| IDO-IN-7 | A potent human IDO inhibitor with IC50 of <1 μM. Synonyms: IDO-IN-7; IDO-IN7; IDO-IN 7.(1R,4r)-4-((R)-2-((S)-6-fluoro-5H-imidazo[5,1-a]isoindol-5-yl)-1-hydroxyethyl)cyclohexanol. Grade:> 98%. CAS No. 1402837-78-8. Molecular formula: C18H21FN2O2. Mole weight: 316.37. | |
| IDO-IN-8 | A potent human IDO inhibitor with IC50 of 1-10 μM. Synonyms: IDO-IN-8; IDO-IN8; IDO-IN 8.(1S,4r)-4-((S)-2-((R)-6-fluoro-5H-imidazo[5,1-a]isoindol-5-yl)-1-hydroxyethyl)cyclohexanol. Grade: > 98%. CAS No. 1402837-77-7. Molecular formula: C18H21FN2O2. Mole weight: 316.37. | |
| Idoxifene | Idoxifene is a non-steroidal estrogen antagonist. It is also structurally analogous to tamoxifen. Idoxifene was both active and well tolerated in postmenopausal women with metastatic breast cancer. Idoxifene had similar efficacy and toxicity to tamoxifen in this randomized comparison. Synonyms: CB7432; 1-[2-[4-[(1E)-1-(4-Iodophenyl)-2-phenyl-1-buten-1-yl]phenoxy]ethyl]-pyrrolidine; trans-1-(4-Iodophenyl)-1-(4-(2'-pyrrolidinoethoxy)phenyl)-2-phenylbutene; (E)-1-[2-[4-[1-(4-iodophenyl)-2-phenyl-1-butenyl]phenoxy]ethyl]-pyrrolidine; SB 223030. Grade: ≥95%. CAS No. 116057-75-1. Molecular formula: C28H30INO. Mole weight: 523.45. | |
| Idoxuridine | 5-Iodo-2'-deoxyuridine is a nucleoside analog that can be incorporated into viral DNA replication to treat herpes simplex keratitis. Uses: 5-iodo-2'-deoxyuridine is a nucleoside analog treat herpes simplex keratitis. Synonyms: 5-Iodo-2'-deoxyuridine; IDU; 2'-Deoxy-5-iodouridine; 5-Iodo-2'-deoxy-D-uridine; 1-(2-Deoxy-β-D-ribofuranosyl)-5-iodouracil; IUdR; Dendrid; Emanil; NSC 39661; Ophthalmadine; Herpesil; Herpidu; Herplex; Stoxil; Stoxip; Synmiol; Virudox. Grade: ≥98% by HPLC. CAS No. 54-42-2. Molecular formula: C9H11IN2O5. Mole weight: 354.10. | |
| IDP TEA salt | IDP TEA salt is a pivotal constituent in the biomedical field, serving as a precursor for crucial molecules engaged in cellular processes. Its applied scope encompasses the synthesis of paramount compounds pertinent to studying viral invasions, immune disorders, and select cancerous conditions. Synonyms: Inosine-5'-diphosphate, triethylammonium salt; Inosine 5'-(trihydrogen diphosphate), triethylammonium salt (1:x); Inosine 5'-(trihydrogen diphosphate), triethylammonium salt; 5'-IDP triethylammonium salt; Inosine 5-diphosphate triethylammonium salt; Inosine diphosphate triethylammonium salt. Grade: ≥95% by HPLC. Molecular formula: C10H14N4O11P2 (free acid). Mole weight: 428.18 (free acid). | |
| IDRA-21 | IDRA-21, an analog of cyclothiazide, inhibits AMPA receptor desensitization and enhances cognition by a related mechanism. IDRA-21 inhibits synaptic and extrasynaptic NMDA receptor mediated events in cultured cerebellar granule cells. Synonyms: 7-Chloro-3-methyl-3-4-dihydro-2H-1,2,4 benzothiadiazine S,S-dioxide; IDRA-21; IDRA 21; IDRA21. CAS No. 22503-72-6. Molecular formula: C8H9ClN2O2S. Mole weight: 232.68. | |
Our database is helping our users find suppliers everyday.
