BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Pimavanserin-[d4] | Pimavanserin-[d4], is the labelled analogue of Pimavanserin, which is an atypical antipsychotic. Synonyms: Pimavanserin-d4; Pimavanserin d4. Molecular formula: C25H30D4FN3O2. Mole weight: 431.59. |  |
| PNC-27 | PNC-27 is an anti-cancer peptide that induces tumor cell necrosis of a poorly differentiated non-solid tissue human leukemia cell line depending on expression of HDM-2 in the plasma membrane of these cells. Grade: 98%. | |
| Polyporenic acid C | Polyporenic acid C is a steroid antibiotic produced by Polyporus betulinus and Polyporus benzoinus. It has strong anti-mycobacterial activity and weak anti-gram-negative bacteria activity. Synonyms: (2R)-2-[(5R,10S,13R,14R,16R,17R)-16-hydroxy-4,4,10,13,14-pentamethyl-3-oxo-1,2,5,6,12,15,16,17-octahydrocyclopenta[a]phenanthren-17-yl]-6-methyl-5-methylideneheptanoic acid. Grade: >98%. CAS No. 465-18-9. Molecular formula: C31H46O4. Mole weight: 482.69. | |
| Pomalidomide-C2-NH2 | Pomalidomide-C2-NH2 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 17 can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1]. Synonyms: 4-((2-aminoethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione; SCHEMBL17884390; TQP0427; Cereblon Ligand-Linker Conjugates 15; HY-128846; Pomalidomide-C2-NH2; Pomalidomide-alkylC2-amine; E3 ligase Ligand 17; 4-[(2-Aminoethyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione hydrochloride. Grade: > 98%. CAS No. 1957235-66-3. Molecular formula: C15H16N4O4. Mole weight: 316.31. | |
| (-)-Praeruptorin B | (-)-Praeruptorin B is a natural coumarin compound found in some plant. Synonyms: (-)-Anomalin; (9R)-2-Oxo-8,8-dimethyl-9,10-dihydro-2H,8H-benzo[1,2-b:3,4-b']dipyran-9α,10α-diol 9,10-bis[(Z)-2-methyl-2-butenoate]; 9,10-Dihydro-8,8-dimethyl-9α,10α-bis[(Z)-1-oxo-2-methyl-2-butenyloxy]-2H,8H-benzo[1,2-b:3,4-b']dipyran-2-one. Grade: >95%. CAS No. 4970-26-7. Molecular formula: C24H26O7. Mole weight: 426.465. | |
| Pramlintide acetate hydrate | Pramlintide is an analog of amylin, an antidiabetic peptide hormone released into the bloodstream. It has been used in the treatment of diabetes. Grade: 98%. CAS No. 196078-30-5. Molecular formula: C173H273N51O56S2. Mole weight: 4027.46. | |
| Prochlorperazine-[d8] Dihydrochloride | Prochlorperazine-[d8] Dihydrochloride, is the labelled analogue of Prochlorperazine. Prochlorperazine is a dopamine (D2) receptor antagonist that belongs to the phenothiazine class of antipsychotic agents, which are used for the antiemetic treatment of nausea and vertigo. Synonyms: Prochlorperazine D8 Dihydrochloride; Prochlorperazine-d8 2HCl (piperazine-d8). Molecular formula: C20H18D8Cl3N3S. Mole weight: 454.91. | |
| Proteinase K | Proteinase K is a subtilisin-related serine protease. It was discovered from the fungus Engyodontium album. It can be used for removal of endogenous nucleases during the preparation of DNA and RNA, and for preparation of tissue sections for in situ hybridization. It is often used in pH range 7.5-9.0 and 37-70°C. Specific activity is ≥ 34 units/mg of protein. Synonyms: EC 3.4.21.64; endopeptidase K; Tritirachium alkaline proteinase; Tritirachium album serine proteinase; Tritirachium album proteinase K. CAS No. 39450-01-6. | |
| Quinocetone-[d5] | Labelled Quinocetone. Quinoenone is a kind of quinoxaline drugs, which can promote growth and increase feed conversion rate, inhibit a variety of intestinal pathogenic bacteria, and can significantly reduce the incidence of diarrhea in livestock and poultry. It is not only suitable for pigs, poultry and aquatic products, but also suitable for disease prevention and growth promotion of young animals and young birds. Synonyms: 1-(3-Methyl-1,4-dioxido-2-quinoxalinyl)-3-phenyl-2-propen-1-one-d5; 1-(3-Methyl-2-quinoxalinyl)-3-phenyl-N,N'-dioxide 2-Propen-1-one-d5. Molecular formula: C18H9D5N2O3. Mole weight: 311.35. | |
| (R)-3-(4-hydroxyphenyl)lactic acid | (R)-3-(4-hydroxyphenyl)lactic acid. Synonyms: (R)-2-Hydroxy-3-(4-hydroxyphenyl)propanoic acid; D-p-Hydroxyphenyllactic acid. Grade: 98%. CAS No. 89919-57-3. Molecular formula: C9H10O4. Mole weight: 182.17. | |
| rac-Monepantel Sulfone-[d5] | rac-Monepantel Sulfone-[d5] is the labelled analogue of rac-Monepantel, which is an impurity of Monepantel. Monepantel is a new anthelmintic agent used in the treatment of parasitic nematodes via stun or kill without damaging the host entity. CAS No. 2747918-68-7. Molecular formula: C20H8D5F6N3O4S. Mole weight: 510.42. | |
| rac-N-Nitroso Mirabegron-[d5] | rac-N-Nitroso Mirabegron-[d5] is a labelled impurity of mirabegron, which is a medication used to treat overactive bladder. Synonyms: 2-(2-aminothiazol-4-yl)-N-(4-(2-((2-hydroxy-2-(phenyl-d5)ethyl)(nitroso)amino)ethyl)phenyl)acetamide. Molecular formula: C21H18D5N5O3S. Mole weight: 430.54. | |
| RADA 16 | RADA 16 is a self-complementary peptide that has been widely studied for various applications in biocompatible materials. Grade: 95%. CAS No. 289042-25-7. Molecular formula: C66H113N29O25. Mole weight: 1712.8. | |
| Radotinib-[d6] | Radotinib-[d6] is deuterium labelled Radotinib. Radotinib, also known as IY-5511, is a second-generation tyrosine kinase inhibitor of Bcr-Abl fusion protein and the platelet-derived growth factor receptor (PDGFR), with potential antineoplastic activity. Synonyms: 4-(Methyl-d3)-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-(pyrazin-2-yl)pyrimidin-2-yl)amino)benzamide-2,5,6-d3. CAS No. 2754051-83-5. Molecular formula: C27H15D6F3N8O. Mole weight: 536.55. | |
| Rapamycin | Rapamycin is an mTOR inhibitor immunosuppressant and kinase inhibitor with both antifungal and antineoplastic properties. It selectively inhibits the transcriptional activation of cytokines. Uses: Antifungal and antineoplastic agent. Synonyms: Sirolimus; (-)-Rapamycin; AY 22989; AY-22989; I-2190A; NSC 226080; RAPA; RAP; RPM; SLM; WY-090217; Everolimus EP Impurity A. Grade: >98%. CAS No. 53123-88-9. Molecular formula: C51H79NO13. Mole weight: 914.19. | |
| Recombinant IGF-I (human) | Recombinant IGF-I (human) is a monoclonal antibody that binds to the epidermal growth factor receptor (EGFR) and inhibits its activity. Synonyms: Recombinant human insulin-like growth factor-1; Human IGF-I; Insulin-like Growth Factor-I (E3R) human; rec IGF-I (human). Grade: ≥95% by SDS-PAGE. CAS No. 67763-96-6. | |
| Resveratrol | Resveratrol is a phytoalexin derived from grapes and other food products with antioxidant and potential chemopreventive activities. Resveratrol induces phase II drug-metabolizing enzymes (anti-initiation activity), mediates anti-inflammatory effects and inhibits cyclooxygenase and hydroperoxidase functions (anti-promotion activity), and induces promyelocytic leukemia cell differentiation (anti-progression activity), thereby exhibiting activities in three major steps of carcinogenesis. This agent may inhibit TNF-induced activation of NF-kappaB in a dose-and time-dependent manner. Resveratrol is a natural compound used in cosmetic materials. It is widely used in anti-aging and wrinkle removal, whitening and whitening spots, antibacterial and anti-inflammatory, oil control and acne, anti-allergy and analgesia, scar repair, hair care and other products, and it is compatible with lotion cream formula, gel formula and water formula. Uses: Ingredient of health care products. Synonyms: trans-Resveratrol; SRT-501; SRT 501; SRT501; RM1812; RM 1812; RM-1812; CA1201; CA 1201; CA-1201; Resvida; Vineatrol 20M; 3,4',5-Trihydroxystilbene; 3,4',5-Stilbenetriol. Grade: ≥98%. CAS No. 501-36-0. Molecular formula: C14H12O3. Mole weight: 228.24. | |
| Rivastigmine-[d6] oxalate | Rivastigmine-[d6] oxalate is a labelled impurity of Rivastigmine. Rivastigmine is a parasympathomimetic or cholinergic drug for the treatment of dementia. Synonyms: Rivastigmine-d6 oxalate; Rivastigmine oxalate-d6; N-Ethyl-N-methylcarbamic Acid 3-[1-(Dimethylamino-d6) ethyl]phenyl Ester; Ethylmethylcarbamic Acid 3-[1-(Dimethylamino-d6)ethyl]phenyl Ester. Molecular formula: C16H18D6N2O6. Mole weight: 346.41. | |
| (R)-Methyl 3-aminobutanoate hydrochloride | (R)-Methyl 3-aminobutanoate hydrochloride. Synonyms: (R)-3-Amino-butyric acid methyl ester, HCl; Methyl (R)-homo-beta-alaninate HCl; Butanoic acid, 3-amino-, methyl ester, hydrochloride (1:1), (3R)-. Grade: 95%. CAS No. 139243-54-2. Molecular formula: C5H12ClNO2. Mole weight: 153.61. | |
| (S)-2-Amino-2-methyl-4-pentenoic acid | (S)-2-Amino-2-methyl-4-pentenoic acid, an analog of amino acid, serves as a versatile ligand for studying the ionotropic glutamate receptors, besides becoming a precursor for synthesizing diverse natural and unnatural amino acids. With its potential therapeutic effects on neural injury and epilepsy, this compound bears immense significance in the realm of neurological research. Synonyms: L-alpha-Allylalanine; 4-Pentenoicacid,2-amino-2-methyl-,(2R)-(9CI); L-α-Methylallylalanine; (S)-2-Amino-2-methyl-4-pentenoic acid; L-α-ALLYLALANINE; (R)-alpha-Allylalanine (>98%, >98%ee); H-alpha-All-L-Ala-OH; (R)-2-amino-2-methylpent-4-enoic acid. Grade: 98%. CAS No. 96886-56-5. Molecular formula: C6H11NO2. Mole weight: 129.16. | |
| (S)-2-Amino-2-methylpent-4-enoic acid | (S)-2-Amino-2-methylpent-4-enoic acid. Synonyms: (S)-2-Amino-2-Methyl-4-Pentenoic Acid; 2-Allyl-D-alanine; (S)-alpha-allylalanine. Grade: 98%. CAS No. 96886-55-4. Molecular formula: C6H11NO2. Mole weight: 129.16. | |
| (S)-2-hydroxy-3-(4-hydroxyphenyl)-propionic acid | A metabolite from the culture medium of Leuconostoc mesenteroides. Synonyms: Latifolicinin C acid; L-p-Hydroxyphenyllactic acid; (S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid. Grade: 98%. CAS No. 23508-35-2. Molecular formula: C9H10O4. Mole weight: 182.17. | |
| Sarafloxacin-[d8] Hydrochloride | Sarafloxacin-[d8] Hydrochloride is the labelled hydrochloride form of Sarafloxacin. Sarafloxacin is a quinolone antibiotic drug, inhibiting the topoisomerase II ligase domain. Synonyms: 6-Fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-7-(1-piperazinyl-d8)-3-quinolinecarboxylic Acid Hydrochloride; A 56620-d8; PD 121960-d8; Sarafin-d8. Grade: >98%. CAS No. 1352879-52-7. Molecular formula: C20H10D8ClF2N3O3. Mole weight: 429.87. | |
| (+)-Scandine | Scandine is a natural alkaloid isolated from the herbs of Melodinus khasianus. Synonyms: 3-(Methoxycarbonyl)meloscine. Grade: >97%. CAS No. 24314-59-8. Molecular formula: C21H22N2O3. Mole weight: 350.4. | |
| Schizokinen | Schizokinen is a siderophore produced by Bacillus megaterium and Anabaena sp. Synonyms: 2-hydroxy-4-((3-(N-hydroxyacetamido)propyl)amino)-2-(2-((3-(N-hydroxyacetamido)propyl)amino)-2-oxoethyl)-4-oxobutanoic acid. CAS No. 35418-52-1. Molecular formula: C16H28N4O9. Mole weight: 420.42. | |
| Secolongifolenediol | Secolongifolenediol is produced in the fermentation broth of Bipolaris eleusines. Synonyms: (1R,6R,9S)-2,2,6-Trimethyl-7-(hydroxymethyl)bicyclo[4.2.1]nona-7-ene-9-Ethanol; Bicyclo[4.2.1]non-7-ene-9-Ethanol, 8-(hydroxymethyl)-1,5,5-trimethyl-, (1R,6R,9S)-; (+)-Secolongifolenediol. Grade: 98.0%. CAS No. 53587-37-4. Molecular formula: C15H26O2. Mole weight: 238.37. | |
| Selank | Selank is a synthetic analogue of human tuftsin and acts as a nootropic, anxiolytic peptide. Synonyms: Thr-Lys-Pro-Arg-Pro-Gly-Pro; Selanc. Grade: 98%. CAS No. 129954-34-3. Molecular formula: C33H57N11O9. Mole weight: 751.9. | |
| Sincalide | It is a synthetically-prepared C-terminal octapeptide of cholecystokinin.Sincalide (INN) is a cholecystokinetic drug administered by injection to aid in diagnosing disorders of the gallbladder and pancreas. It is the 8-amino acid C-terminal fragment of cholecystokinin. Synonyms: Sincalide. Grade: >98%. CAS No. 25126-32-3. Molecular formula: C49H62N10O16S3. Mole weight: 1143.29. | |
| SMCC | SMCC is a heterobifunctional protein crosslinker for antibody-drug-conjugation (ADC). Synonyms: 4-(N-Maleimidomethyl)cyclohexane-1-carboxylic Acid N-Hydroxysuccinimide Ester; NSC 344483; N-Succinimidyl 4-(Maleimidomethyl)cyclohexane-1-carboxylate; Cyclohexanecarboxylic acid, 4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]-, 2,5-dioxo-1-pyrrolidinyl ester; 1H-Pyrrole-2,5-dione, 1-[[4-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]cyclohexyl]methyl]-; 2,5-Dioxopyrrolidin-1-yl 4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexanecarboxylate; 4-(2,5-Dioxo-2,5-dihydro-pyrrol-1-ylmethyl)-cyclohexanecarboxylic acid 2,5-dioxo-pyrrolidin-1-yl ester; N-Hydroxysuccinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate; N-Succinimidyl 4-(maleimidomethyl)cyclohexanecarboxylate; Succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate; Succinimidyl 4-(N-maleimidomethyl)cyclohexanecarboxylate; Succinimidyl 4-[maleimidomethyl]cyclohexan-1-carboxylate. Grade: ≥95%. CAS No. 64987-85-5. Molecular formula: C16H18N2O6. Mole weight: 334.32. | |
| (+)-S-Myricanol glucoside | (+)-S-Myricanol glucoside is a natural phenol isolated from the root bark of Myrica cerifera L. Synonyms: Epimyricanol glucoside. Grade: >98%. CAS No. 449729-89-9. Molecular formula: C27H36O10. Mole weight: 520.6. | |
| Sodium L-glutamate (30% aqueous solution) | Sodium L-glutamate (30% aqueous solution). Synonyms: Disodium glutamate; Disodium cocoyl glutamate; L-Glutamic acid disodium salt; L-Glutamic acid, N-coco acyl derivs., disodium salts. CAS No. 68187-30-4. Molecular formula: C5H7NNa2O4. Mole weight: 191.09. | |
| Spirotryprostatin A | Spirotryprostatin A is an indole alkaloid found in Aspergillus fumigatus fungus, which exhibits anti-mitotic activity. Synonyms: Spiro[5H,10H-dipyrrolo[1,2-a:1',2'-d]pyrazine-2(3H),3'-[3H]indole]-2',5,10(1'H)-trione, 1,5a,6,7,8,10a-hexahydro-6'-methoxy-3-(2-methyl-1-propenyl)-, (2S,3S,5aS,10aS)-; (2S,3S,5aS,10aS)-1,5a,6,7,8,10a-Hexahydro-6'-methoxy-3-(2-methyl-1-propen-1-yl)spiro[5H,10H-dipyrrolo[1,2-a:1',2'-d]pyrazine-2(3H),3'-[3H]indole]-2',5,10(1'H)-trione; (-)-Spirotryprostatin A; (3S,3'S,5'aS,10'aS)-6-Methoxy-3'-(2-methylprop-1-enyl)spiro[1H-indole-3,2'-3,5a,6,7,8,10a-hexahydro-1H-dipyrrolo[1,2-c:1',4'-f]pyrazine]-2,5',10'-trione. Grade: 98.0%. CAS No. 182234-25-9. Molecular formula: C22H25N3O4. Mole weight: 395.45. | |
| (S,R,S)-AHPC | (S,R,S)-AHPC (MDK7526) is the VH032-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC (MDK7526) can be connected to the ligand for protein (e.g., BCR-ABL1) by a linker to form PROTACs (e.g., GMB-475). GMB-475 induces the degradation of BCR-ABL1 with an IC50 of 1.11 μM in Ba/F3 cells. Synonyms: MDK7526; VH032-NH2; VHL ligand 1. CAS No. 1448297-52-6. Molecular formula: C22H30N4O3S. Mole weight: 430.56. | |
| Stachartin A | Stachartin A is produced in the cultures of the tin mine tailings-associated fungus Stachybotrys chartarum. Synonyms: Stachybotrysin; 3-Buten-2-one, 4-[(1'R,2'R,4'aS,6'R,8'aS)-3',4',4'a,5',6',7',8',8'a-octahydro-4,6'-dihydroxy-6-(hydroxymethyl)-2',5',5',8'a-tetramethylspiro[benzofuran-2(3H), 1'(2'H)-naphthalen]-7-yl]-, (3E)-. Grade: 98.0%. CAS No. 1978388-54-3. Molecular formula: C26H36O5. Mole weight: 428.56. | |
| Stachartin C | Stachartin C is produced in the cultures of the tin mine tailings-associated fungus Stachybotrys chartarum. Synonyms: Stachybotrylactone C. Grade: 98.0%. CAS No. 1978388-56-5. Molecular formula: C29H41NO6. Mole weight: 499.64. | |
| Stachartin E | Stachartin E is produced in the cultures of the tin mine tailings-associated fungus Stachybotrys chartarum. Synonyms: Stachybotrylactone E. Grade: 98.0%. CAS No. 1978388-58-7. Molecular formula: C33H41NO6. Mole weight: 547.68. | |
| Strigolactone GR24 | Strigolactone GR24 is a plant hormone that stimulates and regulates shoot branching. Synonyms: (3aR,8bS,E)-3-((((R)-4-methyl-5-oxo-2,5-dihydrofuran-2-yl)oxy)methylene)-3,3a,4,8b-tetrahydro-2H-indeno[1,2-b]furan-2-one; GR24 5DS; 2H-Indeno[1,2-b]furan-2-one, 3-[[[(2R)-2,5-dihydro-4-methyl-5-oxo-2-furanyl]oxy]methylene]-3,3a,4,8b-tetrahydro-, (3E,3aR,8bS)-. Grade: 98%. CAS No. 76974-79-3. Molecular formula: C17H14O5. Mole weight: 298.29. | |
| Succinimidyl Acetate | Succinimidyl Acetate is a non-ionic, acidic ester of succinic anhydride, and is a chemical reagent in a variety of scientific applications. Synonyms: N-Acetoxysuccinimide; 1-(Acetoxy)pyrrolidine-2,5-dione; Ac-Osu; N-Succinimidyl Acetate; Acetic acid N-hydroxysuccinimide ester. Grade: 98%. CAS No. 14464-29-0. Molecular formula: C6H7NO4. Mole weight: 157.12. | |
| Sulbactam Sodium | Sulbactam is an irreversible inhibitor of β-lactamase. It binds to the enzyme and does not allow it to degrade the antibiotic. Synonyms: (2S,5R)-3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid 4,4-Dioxide Sodium Salt; CP 45899-2; Penicillanic Acid 1,1-Dioxide Sodium Salt; Sodium 1,1-Dioxypenicillanate; Sodium Penicillanate 1,1-Dioxide; Sodium Sulbactam; Sulbactam Sodium Salt; Unasyn IM. Grade: Assay: 88.6%. CAS No. 69388-84-7. Molecular formula: C8H10NNaO5S. Mole weight: 255.22. | |
| Sulfabenzamide-[d4] | Sulfabenzamide-[d4] is the labelled analogue of Sulfabenzamide, an antimicrobial agent. Synonyms: Sulfabenzamide-d4; N-[(4-Aminophenyl)sulfonyl]-benzamide-d4; N-(Benzoyl)-4-aminobenzenesulfonamide-d4; N1-Benzoylsulfanilamide-d4. Molecular formula: C13H8D4N2O3S. Mole weight: 280.34. | |
| Sulfaguanidine-[d4] | Sulfaguanidine-[d4] is the labelled analogue of Sulfaguanidine. Sulfaguanidine is a sulfonamide used as an anti-infective agent. Synonyms: Sulfaguanidine-d4. Molecular formula: C7H10N4O2S. Mole weight: 218.27. | |
| Sulfamethoxy pyridazine-[d4] | Isotopic labelled Sulfamethoxy pyridazine. Sulfamethoxy pyridazine is a long-acting sulfonamide antibiotic. It is used for treatment of Dermatitis herpetiformis. Synonyms: 4-Amino-N-(6-methoxy-3-pyridazinyl)-benzenesulfonamide-d4; 3-Methoxy-6-sulfanilamidopyridazine-d4; 6-Sulfanilamido-3-methoxypyridazine-d4; Sultirene-d4; N1-(6-Methoxy-3-pyridazinyl)sulfanilamide-d4; Paramid-d4; Paramid Supra-d4. Grade: >98%. Molecular formula: C11H8D4N4O3S. Mole weight: 284.33. | |
| Sulfo-SMCC sodium | Sulfo-SMCC sodium is a commonly used hetero-bifunctional, noncleavable ADC crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively. Synonyms: Sulfo-SMCC; Sodium 1-((4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexanecarbonyl)oxy)-2,5-dioxopyrrolidine-3-sulfonate. Grade: >98.0%. CAS No. 92921-24-9. Molecular formula: C16H17N2NaO9S. Mole weight: 436.37. | |
| (-)-Syringaresinol | (-)-Syringaresinol is isolated from the rhizomes of Polygonatum kingianum. DL-Syringaresinol inhibits the proliferation of human promyelocytic HL-60 cells through G(1) arrest and induction of apoptosis, may be a potential chemotherapeutic agent for the treatment of cancer. Synonyms: DL-Syringaresinol; (-)-Lirioresinol B; 4,4'-((1R,3aS,4R,6aS)-Tetrahydro-1H,3H-furo(3,4-C)furan-1,4-diyl)bis(2,6-dimethoxyphenol). Grade: 98.0%. CAS No. 6216-81-5. Molecular formula: C22H26O8. Mole weight: 418.44. | |
| Tafamidis-[d3] | Tafamidis-[d3] is deuterium labelled Tafamidis. Tafamidis is a potent and selective transthyretin (TTR) stabilizer, showing comparable potency and efficacy to the mutumant homotetramers V30M-TTR, V122I-TTR and wild type WT-TTR, with EC50s of 2.7-3.2 μM. Tafamidis inhibits amyloidogenesis. Synonyms: Tafamidis-d3; d3-Tafamidis. Molecular formula: C14H4D3Cl2NO3. Mole weight: 311.13. | |
| Tat-NR2B9c TFA | Tat-NR2B9c TFA is a membrane-permeable postsynaptic density-95 (PSD-95)-binding (decoy) peptide and a neuroprotective agent that can inhibit neuronal excitotoxicity. Synonyms: H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Lys-Leu-Ser-Ser-Ile-Glu-Ser-Asp-Val-OH.TFA; L-tyrosyl-glycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-L-arginyl-L-lysyl-L-leucyl-L-seryl-L-seryl-L-isoleucyl-L-alpha-glutamyl-L-seryl-L-alpha-aspartyl-L-valine trifluoroacetic acid; NA-1 TFA. CAS No. 1834571-04-8. Molecular formula: C107H189F3N42O32. Mole weight: 2632.9. | |
| TC-E3 5032 | TC-E3 5032 is a linker used in PROTAC technology that can be used in the synthesis of HDAC6 and anaplastic lymphoma kinase (ALK) degraders. Synonyms: E3 ligase Ligand 4; 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-fluoro-; Thalidomide 4-fluoride; Thalidomide fluoride; 4-Fluoro-thalidomide; Cereblon ligand 4; E3 ligase Ligand 4; 2-(2,6-Dioxo-3-piperidinyl)-4-fluoro-1H-isoindole-1,3(2H)-dione. Grade: ≥ 98%. CAS No. 835616-60-9. Molecular formula: C13H9FN2O4. Mole weight: 276.22. | |
| Tetrahydrocurcumin glucuronide-[d6] | Tetrahydrocurcumin glucuronide-[d6] is an isotopic labelled tetrahydrocurcumin glucuronide, a metabolite of Curcumin with potential to be an antioxidant and anti-inflammatory agent. Synonyms: Tetrahydrocurcumin glucuronide-d6. Molecular formula: C27H26D6O12. Mole weight: 554.57. | |
| Tetrapeptide-21 acetate | Tetrapeptide-21 acetate is a tetrapeptide based on the skin's own structure, with excellent collagen enhancing activity and anti-aging properties. Synonyms: H-Gly-Glu-Lys-Gly-OH.CH3CO2H; GEKG.CH3CO2H; glycyl-L-alpha-glutamyl-L-lysyl-glycine acetic acid. Grade: ≥95%. CAS No. 2763584-13-8. Molecular formula: C17H31N5O9. Mole weight: 449.46. | |
| Tetrapeptide-30 | Tetrapeptide-30 is an oligopeptide composed of four amino acids. Its mechanism of brightening skin is fast and effective, can reduce the number of tyrosinases, and inhibit the activation of melanocytes to lighten the skin. It is suitable for all skin tones. Tetrapeptide-30 is an ingredient in cosmetics with anti-aging effects. Synonyms: Tegopep; L-Prolyl-L-lysyl-L-glutamyl-L-lysine; L-Prolyl-L-lysyl-L-α-glutamyl-L-lysine; Tego Pep 4Even; Tetrapeptide 30. Grade: 98%. CAS No. 1036207-61-0. Molecular formula: C22H40N6O7. Mole weight: 500.59. | |
| Thiabendazole-[d4] | Labelled Thiabendazole. Thiabendazole inhibits the mitochondrial helminth-specific enzyme, fumarate reductase, with anthelminthic property. Synonyms: 2-(4-Thiazolyl)-1H-benzimidazole-d4; 4-(2-Benzymidazolyl)thiazole-d4; MK 360-d4; Equizole-d4; Mertect-d4; Mintezol-d4; Tecto-d4. CAS No. 1190007-20-5. Molecular formula: C10H3D4N3S. Mole weight: 205.27. | |
| Thiamphenicol-methyl-[d3] | Thiamphenicol-methyl-[d3] is the labelled analogue of Thiamphenicol, which is an antimicrobial antibiotic. Synonyms: Thiamphenicol-methyl-d3; 2,2-Dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl-d3)phenyl]ethyl]acetamide. Molecular formula: C12H12D3Cl2NO5S. Mole weight: 359.24. | |
| Threo-6'-Hydroxyustusolate C | Threo-6'-Hydroxyustusolate C is produced from Aspergillus ustus. Synonyms: 2,4-Octadienoic acid, 6,7-dihydroxy-, (5R,5aS,9aS,9bS)-1,3,5,5a,6,7,8,9,9a,9b-decahydro-9b-hydroxy-6,6,9a-trimethyl-1-oxonaphtho[1,2-c]furan-5-yl ester, (2E,4E,6S,7S)-. Grade: 97.5%. CAS No. 1175543-07-3. Molecular formula: C23H32O7. Mole weight: 420.50. | |
| Thymalfasin | Thymalfasin is an immunomodulating agent indicated as an adjuvant for influenza vaccine in elderly patients. Synonyms: Thymosin α1. Grade: 98%. CAS No. 69440-99-9. Molecular formula: C129H215N33O55. Mole weight: 3108.31. | |
| TNF-α (10-36), human | TNF-α (10-36), human is a peptide of human TNF-α. Synonyms: Asp-Lys-Pro-Val-Ala-His-Val-Val-Ala-Asn-Pro-Gln-Ala-Glu-Gly-Gln-Leu-Gln-Trp-Leu-Asn-Arg-Arg-Ala-Asn-Ala-Leu; L-Leucine, L-α-aspartyl-L-lysyl-L-prolyl-L-valyl-L-alanyl-L-histidyl-L-valyl-L-valyl-L-alanyl-L-asparaginyl-L-prolyl-L-glutaminyl-L-alanyl-L-α-glutamylglycyl-L-glutaminyl-L-leucyl-L-glutaminyl-L-tryptophyl-L-leucyl-L-asparaginyl-L-arginyl-L-arginyl-L-alanyl-L-asparaginyl-L-alanyl-; tumor necrosis factor-alpha fragment 10-36 human. Grade: >95%. CAS No. 144796-70-3. Molecular formula: C131H211N43O38. Mole weight: 2996.34. | |
| Tranexamic Acid Trifluoroacetate Salt-[13C6] | Tranexamic Acid Trifluoroacetate Salt-[13C6] is a labelled TFA salt of tranexamic acid which is often used as a lysine analogue to characterize binding sites in plasminogen. Synonyms: trans-4-(Aminomethyl)cyclohexanecarboxylic acid Tranexamsaeure, trifluoroacetate salt-13C6. Molecular formula: C4[13C]6H16F3NO4. Mole weight: 277.19. | |
| Transdermal Peptide | TD-1 binds to Na+/K+-ATPase beta-subunit (ATP1B1) and interacts with the C-terminus of ATP1B1 in yeast and mammalian cells. Synonyms: Transdermal Peptide 1. Grade: 98%. CAS No. 918629-48-8. Molecular formula: C40H66N14O16S2. Mole weight: 1063.17. | |
| trans R-138727-[d4] (Mixture of Diastereomers) | trans R-138727-[d4] (Mixture of Diastereomers) is the labelled analogue of trans R-138727 (Mixture of Diastereomers), which is an active metabolite of Prasugrel. Synonyms: trans R-138727-d4; Prasugrel-d4 Metabolite; (2E)-2-[1-[2-(Cycl; opropyl-d4)-1-(2-fluorophenyl)-2-oxoethyl]-4-mercapto-3-piperidinylidene]acetic Acid; Prasugrel-d4 metabolite R-138727; Prasugrel Impurity 27-d4 (Mixture of Diastereomers). Grade: ≥95%. Molecular formula: C18H16D4FNO3S. Mole weight: 353.44. | |
| Treprostinil-[d9] | Treprostinil-[d9] is a labelled form of Treprostinil. Treprostinil is an analogue of prostacyclin (PGI2) that is used for the treatment of pulmonary arterial hypertension (PAH). Synonyms: 2-{[(1R,2R,3aS)2-hydroxy-1-(3R)-3-hydroxy(4,4,5,5,6,6,7,7,7-D9)heptyl]-1H,2H,3H,3aH,4H,9H,9aH-yl]oxy}acetc acid. Grade: 95% by HPLC; 98% atom D. Molecular formula: C23H25O5D9. Mole weight: 399.58. | |
| Trifluoroacetyl Tripeptide-2 TFA | Trifluoroacetyl Tripeptide-2 TFA. Synonyms: Trifluoroacetyl Tripeptide-2 trifluoroacetate salt. Molecular formula: C23H29F6N3O8. Mole weight: 589.49. | |
| Tripeptide-10 citrulline acetate | Tripeptide-10 citrulline acetate is a synthetic tetrapeptide that improves the quality of collagen. It has anti-wrinkle and cosmetic effects. Synonyms: Tripeptide-10 citrulline (acetate); L-lysyl-L-alpha-aspartyl-L-isoleucyl-L-citrullinamide acetate; H-Lys-Asp-Ile-Cit-NH2.CH3CO2H; KDI-Cit-NH2.CH3CO2H. Grade: ≥95%. CAS No. 2763584-34-3. Molecular formula: C24H46N8O9. Mole weight: 590.68. | |
| Tripeptide-32 | Tripeptide-32, also known as Chronolux, is a synthetic tripeptide composed of three amino acids: proline, serine, and threonine. This peptide is recognized for its hydrating benefits, as it helps to maintain skin moisture by preventing water loss. More remarkably, Tripeptide-32 is claimed to activate genes that regulate the skin's circadian rhythm, including CLOCK and PER1. By modulating the skin's biological clock, it enhances cellular vitality, extends cell lifespan, and protects against environmental stressors such as UV radiation, promoting the repair of DNA damage. This ingredient is particularly beneficial for individuals with irregular sleep patterns, such as night owls or those experiencing jet lag, as it helps to maintain the skin's repair processes during the night. Tripeptide-32 is widely used in cosmetic formulations for its anti-aging and skin repair properties, and it is generally considered safe for use. Synonyms: Chronolux Tripeptide 32; H-Ser-Thr-Pro-NH2; STP; H-STP-NH2; L-Seryl-L-threonyl-L-prolinamide; Chronolux; Tripeptide 32. Grade: ≥95%. CAS No. 1185583-20-3. Molecular formula: C12H22N4O5. Mole weight: 302.33. | |
| Triptolide | Triptolide is a diterpene triepoxide, immunosuppresive agent extracted from the Chinese herb Tripterygium wilfordii. It has immunosuppressive, anti-inflammatory, antiproliferative and antitumour effects. Triptolide is an NF-κB activation inhibitor. Uses: Adcs cytotoxin. Synonyms: NSC 163062; PG490; Trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1(3H)-one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)-, (3bS,4aS,5aS,6R,6aR,7aS,7bS,8aS,8bS)-; (3bS,4aS,5aS,6R,6aR,7aS,7bS,8aS,8bS)-3b,4,4a,6,6a,7a,7b,8b,9,10-Decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)-trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1(3H)-one; (-)-Triptolide; PG 490; Triptolide. Grade: >98%. CAS No. 38748-32-2. Molecular formula: C20H24O6. Mole weight: 360.40. | |
| Tryprostatin A | Tryprostatin A is a natural compound isolated from Aspergillus fumigatus and arrests cell cycle progression at the G2/M phase. Synonyms: (3S,8aS)-3-{[6-methoxy-2-(3-methylbut-2-en-1-yl)-1H-indol-3-yl]methyl}hexahydropyrrolo[1,2-a]pyrazine-1,4-dione. Grade: 98%. CAS No. 171864-80-5. Molecular formula: C22H27N3O3. Mole weight: 381.47. | |
| Tubulysin IM-2 | Tubulysin IM-2 can be used in the synthesis of Tubulysin M. Tubulysin M is a Tubulysin D is a cytotoxic activity tubulysin which inhibits tubulin polymerization and leads to cell cycle arrest and apoptosis. Tubulysin M is used as the cytotoxin in antibody-drug conjugates. Synonyms: 2-((1R,3R)-1-acetoxy-3-((2S,3S)-N,3-dimethyl-2-((R)-1-methylpiperidine-2-carboxamido)pentanamido)-4-methylpentyl)thiazole-4-carboxylic acid, TFA salt. Grade: 95%. Molecular formula: C28H42F3N4O7S. Mole weight: 635.72. | |
| Tubulysin IM-3 | Tubulysin IM-3 can be used in the synthesis of Tubulysin anologs. Tubulysin anologs is a class of microtubule-disrupting agents and can be used as cytotoxins in antibody-drug-conjugation (ADC). Synonyms: ethyl (2S,4R)-4-amino-2-methyl-5-phenylpentanoate hydrochloride. Grade: 95%. Molecular formula: C14H21NO2.HCl. Mole weight: 271.79. | |
| Tyr0-C-Type Natriuretic Peptide (32-53) | Tyr0-C-Type Natriuretic Peptide (32-53), a peptide hormone, is a crucial regulator of the body's fluid and electrolyte balance. Studies have demonstrated its therapeutic potential in cardiovascular and renal diseases. It exerts its effects via the Natriuretic Peptide Receptor C, thus signifying it as a potential drug target for future development though much remains unknown about the precise mechanisms of its action. Synonyms: H-Tyr-Gly-Leu-Ser-Lys-Gly-Cys(1)-Phe-Gly-Leu-Lys-Leu-Asp-Arg-Ile-Gly-Ser-Met-Ser-Gly-Leu-Gly-Cys(1)-OH. Grade: 95%. CAS No. 142878-79-3. Molecular formula: C102H166N28O30S3. Mole weight: 2360.77. | |
| Tyrocidine A TFA | Tyrocidine A is a peptide antibiotic originally isolated from Bac. brevis. It is resistant to gram-positive bacteria and protozoa as well as to a lesser degree to gram-negative bacteria, and it is also resistant to yeast. Synonyms: cyclo-(D-PheProPhe-D-PheAsnGlnTyrValOrnLeu) TFA salt. Grade: 98%. Molecular formula: C66H87N13O13 (free base). Mole weight: 1270.47 (free base). | |
| Urolithin A | Urolithin A is a secondary metabolite of ellagitannins by the gut bacteria. It exhibits anti-inflammatory, antioxidant and antiproliferative effects. Urolithin A can cross the blood brain barrier thus has the potential therapeutic effect against Alzheimer's Disease. Synonyms: 3,8-dihydroxy-6H-benzo[c]chromen-6-one; 3,8-Dihydroxy-6H-dibenzo(b,d)pyran-6-one; 6H-Dibenzo[b,d]pyran-6-one, 3,8-dihydroxy-. Grade: ≥98% by HPLC. CAS No. 1143-70-0. Molecular formula: C13H8O4. Mole weight: 228.20. | |
| Ustusol A | Ustusol A is produced by the strain of Aspergillus ustus. Synonyms: (3S,5S,9R,10S)-3,9,11-trihydroxydrim-7-en-6-one; 3β,9α,11-trihydroxy-6-oxodrim-7-ene; 1(4H)-Naphthalenone, 4a,5,6,7,8,8a-hexahydro-4,7-dihydroxy-4-(hydroxymethyl)-3,4a,8,8-tetramethyl-, (4R,4aS,7S,8aS)-. Grade: 98.0%. CAS No. 1175543-02-8. Molecular formula: C15H24O4. Mole weight: 268.35. | |
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