BOC Sciences 8 - Products

BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.

Product
Travoprost Acid One of the impurities of Travoprost, which has been found to be a selective FP prostaglandin receptor agonist and could be used against glaucoma. Synonyms: (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentyl]-5-heptenoic Acid; (+)-Fluprostenol; [1R-[1α(Z), 2β(1E, 3R*), 3α, 5α]]-7-[3, 5-Dihydroxy-2-[3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentyl]-5-heptenoic Acid; AL 5848; 16-(m-Trifluoromethylphenoxy)-17,18,19,20-tetranorprostaglandin F2&alpha. Grades: 95%. CAS No. 54276-17-4. Molecular formula: C23H29F3O6. Mole weight: 458.48. BOC Sciences 8
Trazodone Impurity C One of the impurities of Trazodone, which has been found to be effective as an antidepressant agent. Synonyms: 2-[3-[4-(4-Chlorophenyl)?-1-piperazinyl]?propyl]?-1,?2,?4-triazolo[4,?3-a]?pyridin-3(2H)?-one. CAS No. 1263278-77-8. Molecular formula: C19H23Cl2N5O. Mole weight: 408.32. BOC Sciences 8
Treprostinil Treprostinil is a vasodilator can be used for the treatment of pulmonary arterial hypertension. It is a synthetic analog of prostacyclin. Treprostinil is an epoprostenol receptor agonist and platelet aggregation inhibitor. Uses: The treatment of pulmonary arterial hypertension. Synonyms: Uniprost; Remodulin; Treprostinilo; Treprostinilum; 2-[[(1R,2R,3aS,9aS)-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[g]naphthalen-5-yl]oxy]acetic acid. Grades: ≥98%. CAS No. 81846-19-7. Molecular formula: C23H34O5. Mole weight: 390.51. BOC Sciences 8
Triamcinolone Benetonide Triamcinolone Benetonide is a glucocorticoid used for the treatment of allergy and inflammation. Uses: Glucocorticoids. Synonyms: Tibicorten; Triamcinolona benetonido; Triamcinoloni benetonidum. CAS No. 31002-79-6. Molecular formula: C35H42FNO8. Mole weight: 623.73. BOC Sciences 8
Triazoledione Triazoledione is a metabolite of Nefazodone, which could be used as an antidepressant for behaving as a SERT and NET inhibitor. Triazoledione has significant affinity for the serotonin 5-HT1A and 5-HT2A receptors, the α1-adrenergic receptor, and the histamine H1 receptor. Synonyms: BMS 180492; 1,2,4-Triazolidine-3,5-dione, 1-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-4-(2-phenoxyethyl)-; 1-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-4-(2-phenoxyethyl)-1,2,4-triazolidine-3,5-dione. Grades: 98%. CAS No. 153707-88-1. Molecular formula: C23H28ClN5O3. Mole weight: 457.96. BOC Sciences 8
Triclonide Triclonide is a topical corticosteroid. Synonyms: TRICLONIDE; 26849-57-0; RS-4464; PSM3RT117Z; (1S, 2S, 4R, 8S, 9S, 11S, 12R, 13S, 19S)-11, 12-dichloro-8-(2-chloroacetyl)-19-fluoro-6, 6, 9, 13-tetramethyl-5, 7-dioxapentacyclo[10.8.0.02, 9.04, 8.013, 18]icosa-14, 17-dien-16-one; Triclonide [USAN:INN]; UNII-PSM3RT117Z; RS 4464; TRICLONIDE [INN]; Triclonide (USAN/INN); TRICLONIDE [USAN]; CHEMBL2107225; SCHEMBL11320466; DTXSID40181367; D06225; Q27286740; 9,11beta,21-Trichloro-6alpha-fluoro-16alpha,17-dihydroxypregna-1,4-diene-3,20-dione cyclic acetal with acetone; Pregna-1,4-diene-3,20-dione, 9,11,21-trichloro-6-fluoro-16,17-((1-methylethylidene)bis(oxy))-, (6alpha,11beta,16alpha)-. Grades: > 95%. CAS No. 26849-57-0. Molecular formula: C24H28Cl3FO4. Mole weight: 505.85. BOC Sciences 8
Trifluoro acetyl amino Linagliptin An impurity of Linagliptin, a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes. Synonyms: (R)-N-(1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)-2,2,2-trifluoroace; Linagliptin Impurity F. CAS No. 1673546-62-7. Molecular formula: C27H27F3N8O3. Mole weight: 568.55. BOC Sciences 8
Trilostane Trilostane is an inhibitor of 3β-hydroxysteroid dehydrogenase used in the treatment of Cushing's syndrome. It is used for the treatment of pituitary-dependent adrenocortical hormone hyperplasia in dogs and the treatment of adrenocortical hormone hyperplasia caused by adrenal cortex tumors in dogs. Synonyms: WIN24540; WIN-24540; WIN 24540; Trilostane; DB01108; D-01180; D 01180; Modrastane. Desopan; Modrenal. Grades: >98%. CAS No. 13647-35-3. Molecular formula: C20H27NO3. Mole weight: 329.43. BOC Sciences 8
Trimipramine Maleate Impurity E Trimipramine Maleate Impurity E is an impurity of the drug Trimipramine Maleate. Synonyms: N1-(3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-2-methylpropyl)-N1,N3,N3,2-tetramethylpropane-1,3-diamine maleic acid; N-[3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-2-methylpropyl]-N,N',N',2-tetramethylpropane-1,3-diamine Maleate; N-[3-(10,11-Dihydro-5H-dibenzo[b,f]azepin-5-yl)-2-methylpropyl]-N,N',N',2-tetramethyl-1,3-propanediamine Maleate; N-(3-(Dimethylamino)-2-Methyl-Propyl)-N-Desmethyltrimipramine Maleate. Molecular formula: C29H41N3O4. Mole weight: 495.65. BOC Sciences 8
Trimipramine N1,N,N,2-tetramethylpropane-1,3-diamine Trimipramine N1,N,N,2-trimethylpropan-1-amine is an impurity of Trimipramine Maleate Salt. Synonyms: N1-(3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-2-methylpropyl)-N1,N3,N3,2-tetramethylpropane-1,3-diamine; N-[3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-2-methylpropyl]-N,N',N',2-tetramethylpropane-1,3-diamine; N-[3-(10,11-Dihydro-5H-dibenzo[b,f]azepin-5-yl)-2-methylpropyl]-N,N',N',2-tetramethyl-1,3-propanediamine; N-(3-(Dimethylamino)-2-Methyl-Propyl)-N-Desmethyltrimipramine. Molecular formula: C25H37N3. Mole weight: 379.58. BOC Sciences 8
Tri-O-tolylphosphine oxide An impurity of Palbociclib, a selective inhibitor of cyclin-dependent kinases CDK4 and CDK6. Palbociclib is developed for the treatment of ER-positive and HER2-negative breast cancer. Synonyms: 1-bis(2-methylphenyl)phosphoryl-2-methylbenzene; Phosphine oxide, tri-o-tolyl-; Phosphine oxide, tris(2-methylphenyl)-. CAS No. 6163-63-9. Molecular formula: C21H21OP. Mole weight: 320.372. BOC Sciences 8
Tri-POC Tenofovir Dimer Cas No. 1093279-77-6. BOC Sciences 8
Trisulfide AVP Trisulfide AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: Trisulfide-Vasopressin; Cys S(1) vasopressin impurity; H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (Trisulfide bridge: Cys1-Cys6); L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-trisulfide; Glycinamide, 3-(thiosulfeno)-L-alanyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-arginyl-, cyclic (1?6)-trisulfide. CAS No. 189241-28-9. Molecular formula: C46H65N15O12S3. Mole weight: 1116.30. BOC Sciences 8
Trisulfide-Calcitonin Trisulfide-Calcitonin is an impurity of Calcitonin salmon, which is a calcium regulating hormone used to be an effective alternative for the treatment of postmenopausal osteoporosis. Synonyms: H-Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2 (Trisulfide formation between Cys1 and Cys7). Molecular formula: C145H240N44O48S3. Mole weight: 3463.96. BOC Sciences 8
Trisulfide Octreotide Trisulfide Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr-ol (Trisulfide Bridge between Cys2-Cys7); D-phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cystyl-L-threoninol (Trisulfide Bridge between Cys2-Cys7); Octreotide EP impurity-E. Grades: ≥95%. CAS No. 1546983-27-0. Molecular formula: C49H66N10O10S3. Mole weight: 1051.31. BOC Sciences 8
Tropifexor Tropifexor is a novel highly potent agonist of farnesoid X receptor (FXR), which regulates bile acid metabolism and signaling. FXR activated by Tropifexor can inhibit bile acid synthesis as well as increase bile acid conjugation, transport and excretion. Tropifexor entered phase II clinical trials for the treatment of NASH and PBC. Synonyms: Tropifexor; LJN452; LJN-452; LJN 452;; 2-[(1R,5S)-3-[[5-cyclopropyl-3-[2-(trifluoromethoxy)phenyl]-1,2-oxazol-4-yl]methoxy]-8-azabicyclo[3.2.1]octan-8-yl]-4-fluoro-1,3-benzothiazole-6-carboxylic acid. Grades: ≥98%. CAS No. 1383816-29-2. Molecular formula: C29H25F4N3O5S. Mole weight: 603.589. BOC Sciences 8
Tropine 4-fluorobenzoate Tropine 4-fluorobenzoate is a tropine derivative of Cocaine, a stimulant drug that inhibits serotonin-norepinephrine-dopamine reuptake. Synonyms: 3-(P-Fluorobenzoyloxy)Tropane; 3α-(4-Fluorobenzoyloxy)tropane; 4-Fluorobenzoic Acid (3-Endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl Ester; Benzoic acid, 4-fluoro-, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester. CAS No. 1392492-03-3. Molecular formula: C15H18FNO2. Mole weight: 263.31. BOC Sciences 8
Trospium Chloride Trospium chloride is a competitive muscarinic cholinergic receptor antagonist. Uses: Urological agents. Synonyms: IP631; IP-631; IP 631; Trospium chloride, brand name Sanctura; Tropez OD; Trosec; Regurin; Flotros; Spasmex; Spasmoly. Grades: >98%. CAS No. 10405-02-4. Molecular formula: C25H30NO3.Cl. Mole weight: 427.96. BOC Sciences 8
Trospium Chloride Related Compound B Trospium Chloride Related Compound B is an impurity of Trospium Chloride, an antispasmodic agent used to treat the symptoms of overactive bladder. Synonyms: Endo-8-Azabicyclo[3.2.1]octan-3-yl 2-hydroxy-2,2-diphenylacetate hydrochloride. Grades: 95%. CAS No. 63516-30-3. Molecular formula: C21H23NO3.HCl. Mole weight: 373.88. BOC Sciences 8
Trp(4)-Octreotide Trp(4)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: L-Trp(4)-Octreotide; D-phenylalanyl-L-cystyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7); H-D-Phe-Cys-Phe-L-Trp-Lys-Thr-Cys-Thr-ol (Disulfide bridge: Cys2-Cys7); (4R,7S,10S,13S,16S,19R)-13-((1H-indol-3-yl)methyl)-19-((R)-2-amino-3-phenylpropanamido)-10-(4-aminobutyl)-16-benzyl-N-((2R,3R)-1,3-dihydroxybutan-2-yl)-7-((R)-1-hydroxyethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carboxamide. Molecular formula: C49H66N10O10S2. Mole weight: 1019.25. BOC Sciences 8
Truncated (32-20)-Calcitonin Truncated (32-20)-Calcitonin is an impurity of Calcitonin salmon, which is a calcium regulating hormone used to be an effective alternative for the treatment of postmenopausal osteoporosis. Synonyms: H-Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-NH2 (Disulfide bridge between Cys1 and Cys7); Calcitonin impurity-30; L-cysteinyl-L-seryl-L-asparagyl-L-leucyl-L-seryl-L-threonyl-L-cysteinyl-L-valyl-L-leucyl-glycyl-L-lysyl-L-leucyl-L-seryl-L-glutaminyl-L-alpha-glutamyl-L-leucyl-L-histidyl-L-lysyl-L-leucinamide (1->7)-disulfide. Molecular formula: C88H152N26O27S2. Mole weight: 2070.46. BOC Sciences 8
Truncated (32-27)-Calcitonin Truncated (32-27)-Calcitonin is an impurity of Calcitonin salmon, which is a calcium regulating hormone used to be an effective alternative for the treatment of postmenopausal osteoporosis. Synonyms: H-Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-NH2 (Disulfide bond between Cys1 and Cys7); L-cysteinyl-L-seryl-L-asparagyl-L-leucyl-L-seryl-L-threonyl-L-cysteinyl-L-valyl-L-leucyl-glycyl-L-lysyl-L-leucyl-L-seryl-L-glutaminyl-L-alpha-glutamyl-L-leucyl-L-histidyl-L-lysyl-L-leucyl-L-glutaminyl-L-threonyl-L-tyrosyl-L-prolyl-L-arginyl-L-threonyl-L-asparaginamide (1->7)-disulfide. Molecular formula: C125H208N38O39S2. Mole weight: 2931.39. BOC Sciences 8
Truncated (32-28)-Calcitonin Truncated (32-28)-Calcitonin is an impurity of Calcitonin salmon, which is a calcium regulating hormone used to be an effective alternative for the treatment of postmenopausal osteoporosis. Synonyms: H-Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-NH2 (Disulfide bridge between Cys1 and Cys7); L-cysteinyl-L-seryl-L-asparagyl-L-leucyl-L-seryl-L-threonyl-L-cysteinyl-L-valyl-L-leucyl-glycyl-L-lysyl-L-leucyl-L-seryl-L-glutaminyl-L-alpha-glutamyl-L-leucyl-L-histidyl-L-lysyl-L-leucyl-L-glutaminyl-L-threonyl-L-tyrosyl-L-prolyl-L-arginyl-L-threonyl-L-asparagyl-L-threoninamide (1->7)-disulfide. Molecular formula: C129H215N39O41S2. Mole weight: 3032.49. BOC Sciences 8
Truncated (32-29)-Calctonin Truncated (32-29)-Calctonin is an impurity of Calcitonin salmon, which is a calcium regulating hormone used to be an effective alternative for the treatment of postmenopausal osteoporosis. Synonyms: H-Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-NH2 (Disulfide bridge between Cys1 and Cys7); Des-Ser-Gly-Thr-Pro-(32-29)-Calcitonin; Calcitonin impurity-31; L-cysteinyl-L-seryl-L-asparagyl-L-leucyl-L-seryl-L-threonyl-L-cysteinyl-L-valyl-L-leucyl-glycyl-L-lysyl-L-leucyl-L-seryl-L-glutaminyl-L-alpha-glutamyl-L-leucyl-L-histidyl-L-lysyl-L-leucyl-L-glutaminyl-L-threonyl-L-tyrosyl-L-prolyl-L-arginyl-L-threonyl-L-asparagyl-L-threonyl-glycinamide (1->7)-disulfide. Molecular formula: C131H218N40O42S2. Mole weight: 3089.54. BOC Sciences 8
Trypsin Inhibitor (soybean) Trypsin Inhibitor (soybean) is a peptide inhibitor of serine proteases that reduces trypsin, as well as plasma kallikrein, thrombin, plasmin, and other serine proteases. Synonyms: Kunitz Trypsin Inhibitor; MR 20; SBTI. CAS No. 9035-81-8. BOC Sciences 8
TT-232 TT 232 is a somatostatin analog that acts as a peptide agonist for sst1/sst4 somatostatin receptors. TT 232 inhibits tyrosine kinase activity in human colon tumor cell lines. TT 232 was shown to suppress proliferation and induce apoptosis in a pancreatic tumor cell line. Synonyms: TT2-32; TT2 32; TT232; TT-232; TT 232; CAP 232; CAP-232; CAP232. CAS No. 147159-51-1. Molecular formula: C45H58N10O9S2. Mole weight: 947.13. BOC Sciences 8
TTNPB TTNPB is an analog of retinoic acid thus acts as a selective agonist of RAR. TTNPB enhances reprogramming efficiency in chemically induced pluripotent stem cells (CiPSCs). Uses: Antineoplastic agents. Synonyms: Arotinoid acid; 4-[(1E)-2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl]-benzoic Acid; (E)-4-[2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl]-benzoic Acid; AGN 191183; Arotinoid free acid; Ro 13-7410; Arotinoic acid. Grades: >98%. CAS No. 71441-28-6. Molecular formula: C24H28O2. Mole weight: 348.48. BOC Sciences 8
TUG-770 TUG-770 displayed excellent physicochemical and in vitro ADME properties, with good aqueous solubility, good chemical stability, low lipophilicity, and decreased plasma protein binding (PPB). TUG-770 furthermore showed excellent stability toward human liver microsomes (HLM), no inhibition of selected CYP-enzymes implicated in drug-drug interactions, no P-glycoprotein (P-gp) inhibition, and good permeability in the Caco-2 cell assay. Examination of TUG-770 in an acute intraperitoneal glucose tolerance test (IPGTT) in normal mice revealed a good dose dependent response with maximal reduction in glucose level reached at 50 mg/kg. The effect of TUG-770 was fully sustained after 29 days of daily oral treatment. Additional evaluation of TUG-770 in rats confirmed a significant glucose lowering effect for the high doses already after 10 min and for all doses after 30 min. Synonyms: TUG-770; TUG 770; TUG770. Grades: >98%. CAS No. 1402601-82-4. Molecular formula: C19H14FNO2. Mole weight: 307.32. BOC Sciences 8
Turofexorate Isopropyl Turofexorate Isopropyl is a highly potent, selective, and orally active farnesoid X receptor (FXR) agonist. Synonyms: WAY-362450; WAY362450; WAY 362450; XL335; XL 335; XL-335; Turofexorate isopropyl. Grades: >98%. CAS No. 629664-81-9. Molecular formula: C25H24F2N2O3. Mole weight: 438.47. BOC Sciences 8
UDP-6-azido-6-deoxy-N-acetyl-D-galactosamine disodium salt UDP-6-azido-6-deoxy-N-acetyl-D-galactosamine disodium salt is a highly significant substance, serving as an indispensable reactive sugar nucleotide analogue for enzyme-mediated labeling and glycoprotein engineering. This compound intricately interweaves within glycosylation-related processes while facilating researchs for cancer, viral infections and autoimmune disorders. Synonyms: UDP-6-azido-6-deoxy-N-acetyl-D-galactosamine sodium salt; UDP 6-azido-6-deoxy-GalNAc sodium salt; UDP 6-azido-6-deoxy-GalNAc disodium salt. Molecular formula: C17H24N6Na2O16P2. Mole weight: 676.33. BOC Sciences 8
UK-371804 UK-371804 is a novel and selective inhibitors of urokinase plasminogen activator (uPA). UK-371804 exhibits excellent enzyme potency (Ki 10 nM) and selectivity profile (4000-fold versus tPA and 2700-fold versus plasmin). Synonyms: 2- ( (4-chloro-1- ( (diaminomethylene) amino) isoquinoline) -7-sulfonamido) -2-methylpropanoic acid; UK-371804; UK371804; UK 371804; UK-371,804; UK 371,804; UK371,804. Grades: >98%. CAS No. 256477-09-5. Molecular formula: C14H16ClN5O4S. Mole weight: 385.82. BOC Sciences 8
Ulinastatin Ulinastatin is an acid-resistant protease inhibitor derived from human urine, acting as a potent anti-inflammatory agent. It was shown to inhibit the activities of a variety of enzymes, including trypsin, chymotrypsin, thrombin, kallikrein, plasmin, elastase, cathepsin, lipase, hyaluronidase, factors IXa, Xa, XIa, and XlIa, and polymorphonuclear leukocyte elastase. Synonyms: Urinastatin; 2,4-Dioxaspiro[5.5]undec-8-ene, 3-(2-furanyl)-. Grades: 95%. CAS No. 80449-31-6. Molecular formula: C13H16O3. Mole weight: 220.26. BOC Sciences 8
Ulipristal Ulipristal is a selective SPRM for emergency contraception after an unprotected intercourse or contraceptive failure. Synonyms: CDB-2914; CDB2914; CDB 2914; Ulipristal; VA-2914; VA 2914; VA2914; PGL-4001; PGL 4001; PGL4001. Grades: >98%. CAS No. 159811-51-5. Molecular formula: C28H35NO3. Mole weight: 433.58. BOC Sciences 8
Ulipristal Acetate Ulipristal Acetate is an orally bioactive and selective progesterone receptor modulator (SPRM) used for emergency contraception and uterine fibroid. It binds to the progesterone receptor (PR) to inhibit PR-mediated gene expression. Uses: Emergency contraception and uterine fibroid. Synonyms: Ella; EllaOne; Ulipristal (acetate); CDB-2914; [(8S,11R,13S,14S,17R)-17-acetyl-11-[4-(dimethylamino)phenyl]-13-methyl-3-oxo-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl] acetate; CDB 2914; CDB2914. Grades: 98%. CAS No. 126784-99-4. Molecular formula: C30H37NO4. Mole weight: 475.62. BOC Sciences 8
Umbralisib Umbralisib is an orally bioavailable and selective PI3K delta inhibitor that targets delta isoform with nanomolar potency, which is approximately 1000-fold selective over alpha isoform, >30-50 fold over beta isoform and >15-50 fold over gamma isoforms. Umbralisib is developed for lymphoma therapy. Synonyms: TGR-1202; TGR 1202; TGR1202; RP5264; 2-[(1S)-1-[4-amino-3-(3-fluoro-4-propan-2-yloxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]ethyl]-6-fluoro-3-(3-fluorophenyl)chromen-4-one. CAS No. 1532533-67-7. Molecular formula: C31H24F3N5O3. Mole weight: 571.5. BOC Sciences 8
Umeclidinium bromide Umeclidinium bromide(GSK573719A) is a muscarinic receptor antagonist which is useful in treatment of chronic obstructive pulmonary disease (COPD). Synonyms: GSK-573719, GSK573719, GSK 573719, GSK-573719A, GSK573719A, GSK 573719A, Incruse Ellipta, Umeclidinium bromide. Grades: 0.99. CAS No. 869113-09-7. Molecular formula: C29H34BrNO2. Mole weight: 508.5. BOC Sciences 8
Umifenovir Arbidol is an antiviral agent using for the treatment of influenza infection in Russia and China. It inhibits membrane fusion and prevents contact between the virus and target host cells. Fusion between the viral capsid and the cell membrane of the target cell is inhibited and this prevents viral entry to the target cell. Although some Russian studies have shown it to be effective, it is not approved for use in Western countries. Synonyms: Arbidol; 6-Bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylthio)methyl]-1H-indole-3-carboxylic Acid Ethyl Ester. Grades: ≥95%. CAS No. 131707-25-0. Molecular formula: C22H25BrN2O3S. Mole weight: 477.41. BOC Sciences 8
Umifenovir Glucuronide Umifenovir Glucuronide is an impurity of Arbidol, which is an antiviral agent used for the treatment of influenza infection. Synonyms: 6-Bromo-4-[(dimethylamino)methyl]-3-(ethoxycarbonyl)-1-methyl-2-[(phenylthio)methyl]-1H-indol-5-yl β-D-glucopyranosiduronic Acid; Arbidol O-Glucuronide; 6-Bromo-4-[(dimethylamino)methyl]-3-(ethoxycarbonyl)-1-methyl-2-[(phenylsulfanyl)methyl]-1H-indol-5-yl β-D-glucopyranosiduronic acid; 1H-Indole-3-carboxylic acid, 6-bromo-4-[(dimethylamino)methyl]-5-(β-D-glucopyranuronosyloxy)-1-methyl-2-[(phenylthio)methyl]-, ethyl ester. Grades: >98%. CAS No. 1130900-96-7. Molecular formula: C28H33BrN2O9S. Mole weight: 653.54. BOC Sciences 8
Umifenovir Sulfate Umifenovir Sulfate is an impurity of Arbidol, which is an antiviral agent used for the treatment of influenza infection. Synonyms: Ethyl 6-bromo-4-[(dimethylamino)methyl]-1-methyl-2-[(phenylsulfanyl)methyl]-5-(sulfooxy)-1H-indole-3-carboxylate; 1H-Indole-3-carboxylic acid, 6-bromo-4-[(dimethylamino)methyl]-1-methyl-2-[(phenylthio)methyl]-5-(sulfooxy)-, 3-ethyl ester; 3-Ethyl Ester 6-Bromo-4-[(dimethylamino)methyl]-1-methyl-2-[(phenylthio)methyl]-5-(sulfooxy)-1H-indole-3-carboxylic Acid; Arbidol Sulfate. Grades: >98%. CAS No. 1443454-70-3. Molecular formula: C22H25BrN2O6S2. Mole weight: 557.48. BOC Sciences 8
UNC-0638 UNC0638 is an inhibitor of G9a and GLP with excellent potency and selectivity over a wide range of epigenetic and non-epigenetic targets. UNC0638 treatment of a variety of cell lines resulted in lower global H3K9me2 levels, equivalent to levels observed for small hairpin RNA knockdown of G9a and GLP with the functional potency of UNC0638 being well separated from its toxicity. UNC0638 markedly reduced the clonogenicity of MCF7 cells, reduced the abundance of H3K9me2 marks at promoters of known G9a-regulated endogenous genes and disproportionately affected several genomic loci encoding microRNAs. Synonyms: UNC0638, UNC-0638, UNC 0638. Grades: 0.98. CAS No. 1255580-76-7. Molecular formula: C30H47N5O2. Mole weight: 509.739. BOC Sciences 8
UNC1215 UNC1215 is a potent, selective antagonist of L3MBTL3 with cellular activity. UNC1215 has an IC50 of 20 nM and > 100-fold selectivity over 13 HMTs and selected representatives of kinases, ion channels, 7TMs, and other epigenetic proteins. Synonyms: UNC1215, UNC-1215, UNC 1215; (2-(phenylamino)-1,4-phenylene)bis((4-(pyrrolidin-1-yl)piperidin-1-yl)methanone). Grades: >98%. CAS No. 1415800-43-9. Molecular formula: C32H43N5O2. Mole weight: 529.729. BOC Sciences 8
UNC-1999 UNC1999, the first orally bioavailable inhibitor that has high in vitro potency for wildtype and mutant EZH2 as well as EZH1. UNC1999 was highly selective for EZH2 and EZH1 over a broad range of epigenetic and non-epigenetic targets. UNC1999 was orally bioavailable in mice, making this inhibitor a valuable tool for investigating the role of EZH2 and EZH1 in chronic animal studies. UNC-1999 represents a useful tools for the biomedical community to investigate the role of EZH2 and EZH1 in health and disease. Synonyms: UNC1999; UNC 1999; UNC-1999. Grades: 0.98. CAS No. 1431612-23-5. Molecular formula: C33H43N7O2. Mole weight: 569.754. BOC Sciences 8
UNC-2025 UNC-2025 is a novel potent and highly orally bioavailable Mer/FLT3 dual inhibitor, capable of inhibiting Mer phosphorylation in vivo, following oral dosing as demonstrated by pharmaco-dynamic (PD) studies examining phospho-Mer in leukemic blasts from mouse bone marrow. Kinome profiling versus more than 300 kinases in vitro and cellular selectivity assessments demonstrate that UNC-2025 has similar subnanomolar activity against Flt3, an additional important target in acute myelogenous leukemia (AML), with pharmacologically useful selectivity versus other kinases examined. Synonyms: Cyclohexanol, 4-[2-(butylamino)-5-[4-[(4-methyl-1-piperazinyl)methyl]phenyl]-7H-pyrrolo[2,3-d]pyrimidin-7-yl]-, trans-; trans-4-[2-(Butylamino)-5-[4-[(4-methyl-1-piperazinyl)methyl]phenyl]-7H-pyrrolo[2,3-d]pyrimidin-7-yl]cyclohexanol; MRX 6313; UNC 2025; UNC2025. Grades: ≥95%. CAS No. 1429881-91-3. Molecular formula: C28H40N6O. Mole weight: 476.66. BOC Sciences 8
UNC-2025 hydrochloride UNC-2025 hydrochloride is the hydrochloride salt of UNC-2025, which is the Mer/FLT3 dual inhibitor. Synonyms: UNC-2025 hydrochloride; UNC 2025 hydrochloride; UNC2025 hydrochloride; (1r,4r)-4-(2-(butylamino)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)cyclohexanol hydrochloride. Grades: >98%. CAS No. 2070015-17-5. Molecular formula: C28H41ClN6O. Mole weight: 513.12. BOC Sciences 8
UNC2250 UNC2250 is a potent and selective Mer Kinase inhibitor. When applied to live cells, UNC2250 inhibited steady-state phosphorylation of endogenous Mer with an IC50 of 9.8 nM and blocked ligand-stimulated activation of a chimeric EGFR-Mer protein. Treatment with UNC2250 also resulted in decreased colony-forming potential in rhabdoid and NSCLC tumor cells. The results provide a rationale for further investigation of UNC2250 for therapeutic application in patients with cancer. Synonyms: UNC-2250; UNC 2250. Grades: 98%. CAS No. 1493694-70-4. Molecular formula: C24H36N6O2. Mole weight: 440.58. BOC Sciences 8
UNC 3230 UNC 3230 is a potent and selective PIP5K1C inhibitor (IC50 = 41 nM), displaying selectivity for PIP5K1C over PIP5K1A, the PI 3-kinase family and a panel of other kinases. UNC 3230 decreases PIP2 levels and LPA-induced calcium signaling in dorsal root ganglia (DRG) neurons in vitro. UNC 3230 exhibits antinociceptive effects in mouse models of chronic pain. Synonyms: UNC3230; UNC-3230; UNC 3230; 5-[(Cyclohexylcarbonyl)amino]-2-(phenylamino)-thiazolecarboxamide. Grades: ≥99% by HPLC. CAS No. 1031602-63-7. Molecular formula: C17H20N4O2S. Mole weight: 344.43. BOC Sciences 8
Upadacitinib Upadacitinib is a selective JAK inhibitor under the development of AbbVie.ABT-494 is nearly 74 fold selective for Jak1 over Jak2 in cellular assays dependent on specific, relevant cytokines. Preliminary evidence suggests that ABT-494 may spare Jak2 and Jak3 dependent signaling compared to tofacitinib. Phase II for the treatment of Atopic dermatitis and Crohn's disease, Phase III for the treatment of Rheumatoid arthritis and Ulcerative colitis was on-going. Uses: Rheumatoid arthritis; ulcerative colitis;atopic dermatitis; crohn's disease. Synonyms: UNII-4RA0KN46E0;ABT494;(3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide. Grades: 98%. CAS No. 1310726-60-3. Molecular formula: C17H19F3N6O. Mole weight: 380.37. BOC Sciences 8
Upamostat This active molecular is 3-amidinophenylalanine-derived prodrug targeting the human urokinase plasminogen activator (uPA) system. It is a second generation serine protease inhibitor with potential antineoplastic and antimetastatic activities. Though inhibition of uPA may lead to inhibit growth and metastasis of tumor. In Jan 2016, Link Health planed a phase I trial for Solid tumours in China and two phase II trials in Cancer. Synonyms: 1-Piperazinecarboxylic acid, 4-[ (2S) -3-[3-[ (E) -amino (hydroxyimino) methyl]phenyl]-1-oxo-2-[[[2, 4, 6-tris (1-methylethyl) phenyl]sulfonyl]amino]propyl]-, ethyl ester; Ethyl 4-[ (2S) -3-[3-[ (E) -amino (hydroxyimino) methyl]phenyl]-1-oxo-2-[[[2, 4, 6-tris (1-methylethyl) phenyl]sulfonyl]amino]propyl]-1-piperazinecarboxylate; RHB 107; RHB-107; RHB107. Grades: 98%. CAS No. 1191101-18-4. Molecular formula: C32H47N5O6S. Mole weight: 629.82. BOC Sciences 8
Uprosertib Uprosertib, also known as GSK2141795 and GSK795, is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Akt inhibitor GSK2141795 binds to and inhibits the activity of Akt, which may result in inhibition of the PI3K/Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis. Activation of the PI3K/Akt signaling pathway is frequently associated with tumorigenesis and dysregulated PI3K/Akt signaling may contribute to tumor resistance to a variety of antineoplastic agents. Synonyms: GSK-2141795; GSK2141795; GSK 2141795; GSK795; GSK-795; GSK 795. Uprosertib. CAS No. 1047634-65-0. Molecular formula: C18H16Cl2F2N4O2. Mole weight: 429.25. BOC Sciences 8
USP Almotriptan Related Compound A; A metabolite of Almotriptan. Synonyms: 3-[2-(Dimethylamino)ethyl]-5-[(1-pyrrolidinylsulfonyl)methyl]-1H-indole-1-methanol. Grades: > 95%. CAS No. 1018676-02-2. Molecular formula: C18H27N3O3S. Mole weight: 365.5. BOC Sciences 8
USP Cyclophosphamide Related Compound A Bis(2-chloroethyl)amine hydrochloride is a cytotoxic metabolite of Cyclophosphamide, which is an alkylating agent of the nitrogen mustard type with antineoplastic and immunosuppressive activities. Synonyms: Ethanamine, 2-chloro-N-(2-chloroethyl)-, hydrochloride (1:1); Bis(2-chloroethyl)amine Hydrochloride; 2-Chloro-N-(2-chloroethyl)ethanamine Hydrochloride; Diethylamine, 2,2'-dichloro-, hydrochloride; Ethanamine, 2-chloro-N-(2-chloroethyl)-, hydrochloride; 1,5-Dichloro-3-azapentane hydrochloride; 2,2'-Dichlorodiethylamine hydrochloride; Bis(2-chloroethyl)ammonium chloride; Bis(β-chloroethyl)amine hydrochloride; Di(2-chloroethyl)amine hydrochloride; Leo 72a; N,N-Bis(2-chloroethyl)amine hydrochloride; Nornitrogen mustard hydrochloride; NSC 10873; β,β'-Dichlorodiethylamine hydrochloride. Grades: ≥95%. CAS No. 821-48-7. Molecular formula: C4H10Cl3N. Mole weight: 178.49. BOC Sciences 8
USP Valacyclovir Related Compound D Cas No. 1346747-69-0. BOC Sciences 8
Vabicaserin hydrochloride Vabicaserin is a 5-HT2C receptor agonist and 5-HT2B receptor antagonist. It has the potential to treat Schizophrenia. Synonyms: Vabicaserin HCl; SCA 136; SCA-136; SCA136. CAS No. 887258-94-8. Molecular formula: C15H21ClN2. Mole weight: 264.79. BOC Sciences 8
Vadadustat Vadadustat is a potent HIF (Hypoxia-inducible factor) inhibitor. It is under development for the treatment of anemia due to chronic kidney disease in adult patients on dialysis. Synonyms: AKB-6548; AKB 6548; AKB6548; PG-1016548. CAS No. 1000025-07-9. Molecular formula: C14H11ClN2O4. Mole weight: 306.7. BOC Sciences 8
Valacyclovir Related Compound D An impurity of Valacyclovir, an antiviral drug used for the treatment of herpes virus infections. Synonyms: Valaciclovir USP RC D; N-Ethyl Valacyclovir ; 2-[(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethyl-N-ethyl-L-valinate. Grades: > 95%. CAS No. 1346747-69-0. Molecular formula: C15H15N5O4. Mole weight: 352.39. BOC Sciences 8
Valacyclovir Related Compound F An impurity of Acyclovir. Synonyms: L-Valine 2-hydroxyethyl ester p-toluenesulfonate salt. Grades: > 95%. CAS No. 86150-61-0. Molecular formula: C7H15NO3 C7H8O3S. Mole weight: 161.20 172.20. BOC Sciences 8
Valdecoxib Impurity B Valdecoxib Impurity B is a dimeric impurity of Valdecoxib. Synonyms: Valdecoxib Dimer; N-[4-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonyl]-4-(5-methyl-3-phenyl-4-isoxazolyl)benzenesulfonamide. CAS No. 1373038-60-8. Molecular formula: C32H25N3O6S2. Mole weight: 611.7. BOC Sciences 8
Valdecoxib Impurity E An impurity of Valdecoxib. Valdecoxib is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, rheumatoid arthritis, etc. Valdecoxib exhibits a selectively inhibitory effect of cyclooxygenase-2. Synonyms: Valdecoxib IMpurity-E; 3-(4-(4-(Chlorosulfonyl)phenyl)-5-methylisoxazol-3-yl)benzenesulfonyl chloride; 3-[4-(4-chlorosulfonylphenyl)-5-methyl-1,2-oxazol-3-yl]benzenesulfonyl chloride; 3-(4-(4-(Chlorosulfonyl)phenyl)-5-methylisoxazol-3-yl)benzene-1-sulfonyl chloride; YEC03863; 3-[4-[4-(Chlorosulfonyl)phenyl]-5-methyl-3-isoxazolyl]benzenesulfonyl chloride; 1-?Tert-?butyl 4-?ethyl 1H-?pyrazole-?1,?4-?dicarboxylate. CAS No. 1373038-63-1. Molecular formula: C16H11Cl2NO5S2. Mole weight: 432.3. BOC Sciences 8
Valdecoxib Impurity I An impurity of Valdecoxib. Valdecoxib is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, rheumatoid arthritis, etc. Valdecoxib exhibits a selectively inhibitory effect of cyclooxygenase-2. Synonyms: 3-(5-methyl-4-(4-sulfamoylphenyl)isoxazol-3-yl)benzenesulfonamide; AKOS030530317; ZINC200584589; BC600176; 3-(3-Aminosulfonylphenyl)-4-(4-aminosulfonylphenyl)-5-methylisoxazole. CAS No. 1373038-59-5. Molecular formula: C16H15N3O5S2. Mole weight: 393.44. BOC Sciences 8
Valdecoxib Impurity J The prodrug Parecoxib as well as its active metabolite val have a specific affinity to the cannabinoid (CB) receptor measured in CB1-expressing HEK 293 cells and rat brain tissue. Adult male Sprague-Dawley rats were administered parecoxib (10 or 30 mg kg(-1), IP) or isotonic saline twice a day starting 24 h after middle cerebral artery occlusion (MCAO) for three consecutive days. The selective COX-2 inhibitor parecoxib was delivered 20 min before or 20 min after the incision by intraperitoneal injection. Pretreatment with parecoxib markedly attenuated the pain hypersensitivity induced by incision. Uses: Cyclooxygenase 2 inhibitors. Synonyms: SC 69124; SC69124; SC-69124; Valus-P; Vorth-P. Grades: >98%. CAS No. 198470-84-7. Molecular formula: C19H18N2O4S. Mole weight: 370.42. BOC Sciences 8
Valerophenone Valerophenone is an aromatic ketone that is often used as a tool in the study of various photochemical processes. It is also an inhibitor of the enzyme carbonyl reductase. Uses: Benzylhexahydropyrrolo[3,2-b]pyrrole-1(2h)-carboxylate (cas# 1251009-14-9) is a useful research chemical. Synonyms: 1-phenylpentan-1-one. Grades: > 95 %. CAS No. 1009-14-9. Molecular formula: C11H14O. Mole weight: 162.23. BOC Sciences 8
Valganciclovir In cell culture model systems using Caco-2 cells for PEPT1 and SKPT cells for PEPT2, valganciclovir inhibited glycylsarcosine transport mediated by PEPT1 and PEPT2 with K(I) values (inhibition constant) of 1.68+/-0.30 and 0.043+/- 0.005 mM, respectively. The inhibition by valganciclovir was competitive in both cases. 37 patients were enrolled; 19 patients received treatment with VGV and 18 patients received treatment with GCV. The VGV was not inferior in efficacy to GCV as pre-emptive therapy, with rates of viral clearance at 28 days of 89.5% and 83%, respectively (P-value for non-inferiority = 0.030). Toxicities were similar between the 2 arms. No patients developed CMV disease. Patients being treated with an alemtuzumab-containing regimen received prophylaxis with either valaciclovir 500 mg orally daily orvalganciclovir 450 mg orally twice daily. None of the 20 patients randomized to valganciclovir experienced CMV reactivation (P =.004). Synonyms: Valganciclovir. Grades: >98%. CAS No. 175865-60-8. Molecular formula: C14H22N6O5. Mole weight: 354.36. BOC Sciences 8
Valganciclovir Impurity C Valganciclovir Impurity C is a derivative of guanine which is on one of the five nucleobases incorporated into biological nucleic acids. Synonyms: 9-Methoxymethyl Guanine; 2-Amino-1,9-dihydro-9-(methoxymethyl)-6H-purin-6-one. Grades: > 95%. CAS No. 1202645-50-8. Molecular formula: C7H9N5O2. Mole weight: 195.18. BOC Sciences 8
Valganciclovir Impurity D Grades: > 95%. Molecular formula: C14H23N6O5Cl. Mole weight: 390.83. BOC Sciences 8
Vandetanib Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 with IC50 of 40 nM. Uses: Antineoplastic. Synonyms: ZD6474; ZD 6474; ZD-6474; 4-Quinazolinamine, N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methyl-4-piperidinyl)methoxy]-; N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-[(1-methyl-4-piperidinyl)methoxy]-4-quinazolinamine; 4-(4-Bromo-2-fluoroanilino)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazoline; AZD 6474; AZD-6474; AZD6474; Caprelsa; CH 331; N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-(N-methylpiperidin-4-ylmethoxy)quinazolin-4-amine; Zactima. Grades: >98%. CAS No. 443913-73-3. Molecular formula: C22H24BrFN4O2. Mole weight: 475.35. BOC Sciences 8
Vanillyl ethyl ether Synonyms: Ethyl vanillyl ether; Ethyl 4-hydroxy-3-methoxybenzyl ether; 4-hydroxy-3-methoxybenzyl ethyl ether; Phenol, 4-(ethoxymethyl)-2-methoxy-. CAS No. 13184-86-6. Molecular formula: C10H14O3. Mole weight: 182.22. BOC Sciences 8
Vanillylmethanol 4-Sulfate Sodium Salt Vanillylmethanol 4-Sulfate Sodium Salt is a derivative of vanillylmethanol, which is an odorant in strawberries, grapes and olive oil. Synonyms: 3-Methoxy-4-(sulfooxy)-benzeneethanol Sodium Salt. Grades: 98%. Molecular formula: C9H11NaO6S. Mole weight: 270.23. BOC Sciences 8
Varenicline Carbamoyl 2,3,4-Tri-O-acetyl-β-D-glucuronide Methyl Ester Varenicline Carbamoyl 2,3,4-Tri-O-acetyl-β-D-glucuronide Methyl Ester is one of Varenicline metabolites. Varenicline is a nicotinic receptor partial agonist. It's a prescription drug used to treat cigarette addiction. Synonyms: [(2S,3R,4S,5S,6S)-3,4,5-triacetyloxy-6-methoxycarbonyloxan-2-yl] 5, 8, 14-triazatetracyclo[10.3.1.02, 11.04, 9]hexadeca-2, 4, 6, 8, 10-pentaene-14-carboxylate; 1-(6,7,9,10-Tetrahydro-6,10-methano-8H-pyrazino[2,3-h][3]benzazepin-8-carboxylate)2,3,4-Tri-O-acetyl-β-D-glucopyranuronic Acid Methyl Ester; Methyl 2, 3, 4-tri-O-acetyl-1-O-[5, 8, 14-triazatetracyclo[10.3.1.02, 11.04, 9]hexadeca-2(11), 3, 5, 7, 9-pentaen-14-ylcarbonyl]-β-D-glucopyranuronate; β-D-Glucopyranuronic acid, 1-O-[(6,7,9,10-tetrahydro-6,10-methano-8H-azepino[4,5-g]quinoxalin-8-yl)carbonyl]-, methyl ester, 2,3,4-triacetate. Molecular formula: C27H29N3O11. Mole weight: 571.53. BOC Sciences 8
Varenicline Carbamoyl β-D-Glucuronide Methyl Ester Varenicline Carbamoyl β-D-Glucuronide Methyl Ester is one of Varenicline metabolites. Varenicline is a nicotinic receptor partial agonist. It's a prescription drug used to treat cigarette addiction. Synonyms: 1-(6,7,9,10-Tetrahydro-6,10-methano-8H-pyrazino[2,3-h][3]benzazepin-8-carboxylate) β-D-Glucopyranuronic Acid Methyl Ester; [(2S,3R,4S,5S,6S)-3,4,5-trihydroxy-6-methoxycarbonyloxan-2-yl] 5, 8, 14-triazatetracyclo[10.3.1.02, 11.04, 9]hexadeca-2, 4, 6, 8, 10-pentaene-14-carboxylate; Methyl 1-O-[5, 8, 14-triazatetracyclo[10.3.1.02, 11.04, 9]hexadeca-2(11), 3, 5, 7, 9-pentaen-14-ylcarbonyl]-β-D-glucopyranuronate; β-D-Glucopyranuronic acid, 1-O-[(6,7,9,10-tetrahydro-6,10-methano-8H-azepino[4,5-g]quinoxalin-8-yl)carbonyl]-, methyl ester. Molecular formula: C21H23N3O8. Mole weight: 445.42. BOC Sciences 8
Varenicline Lactam Varenicline Lactam is one of Varenicline metabolites. Varenicline is a nicotinic receptor partial agonist. It's a prescription drug used to treat cigarette addiction. Uses: A metabolite of varenicline. Synonyms: 6,8,9,10-Tetrahydro-6,10-methano-7H-pyrazino[2,3-h][3]benzazepin-7-one; Varenicline Lactam Impurity; 6,10-Methano-7H-pyrazino[2,3-h][3]benzazepin-7-one, 6,8,9,10-tetrahydro-. Grades: ≥95%. CAS No. 873302-30-8. Molecular formula: C13H11N3O. Mole weight: 225.25. BOC Sciences 8

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