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Astragaloside IV
Astragaloside IV is extracted from roots of Astragalus membranaceus (Fisch.) Bunge. It has anti-aging properties, antioxidant, anti-inflammatory and anti-fibrotic effects in systemic sclerosis. It inhibits migration and invasion in human lung cancer A549 cells via regulating PKC-α-ERK1/2-NF-κB pathway. Astragaloside IV is a natural compound used in cosmetics material. Uses: Cardiovascular protection. Synonyms: 9,19-Cyclolanostan-beta-D-glucopyranoside; 20,24-epoxy-16,25-dihydroxy-3-(β-D-xylopyranosyloxy)-9,19-cyclolanostan-6-yl. Grade: >98%. CAS No. 84687-43-4. Molecular formula: C41H68O14. Mole weight: 784.97.
AT-265
AT-265 is a nucleoside antibiotic produced by Streptomyces rishiensis. It has anti-gram-positive and negative bacteria activity. Synonyms: 5'-Sulfamoyl-2-chloroadenosine; 2-chloro-5'-o-sulfamoyladenosine; Antibiotic AT 265. Grade: >98%. CAS No. 66522-52-9. Molecular formula: C10H13ClN6O6S. Mole weight: 380.77.
Atractylenolide I
Atractylenolide I is a sesquiterpenoid found in the rhizome of Atractylodes macrocephala. Atractylenolide I ameliorates sepsis syndrome by reduction of pro-inflammatory cytokines and LPS, and provides an improvement in liver and kidney functions. Uses: Anti-inflammatory. Synonyms: ATRACTYLENOLIDE-1; (4aS,8aS)-4a,5,6,7,8,8a-Hexahydro-3,8a-dimethyl-5-methylenenaphtho[2,3-b]furan-2(4H)-one; 3,8aβ-Dimethyl-5-methylene-2,4,4aα,5,6,7,8,8a-octahydronaphtho[2,3-b]furan-2-one; Eudesma-4(15),7(11),8-trien-12-olide; 8,9-Dehydroasterolide. Grade: >98%. CAS No. 73069-13-3. Molecular formula: C15H18O2. Mole weight: 230.3.
Atractylodin
Atractylodin is an active component of the essential oil contained in the rhizomes of Atractylodes lancea and A. Uses: Anti-inflammatory. Synonyms: Atractydin. Grade: >98%. CAS No. 55290-63-6. Molecular formula: C13H10O. Mole weight: 182.22.
Atranorin
Atranorin, which can be found in the herbs of Parmelia tinctorum Despr, has a relevant redox-active action, acting as a pro-oxidant or antioxidant agent depending on the radical. Also, it will exert cytoprotective effects on cells under oxidative stress induced by H(2)O(2). It was found to be more efficient at equitoxic doses and correlated more strongly with an increased number of floating cells or a higher apoptotic index. It also exhibited significant anti-inflammatory activity in the acute model of inflammation (leukocyte migration to the peritoneal cavity), carrageenan- and arachidonic acid-induced hind paw edema in rats. Besides, Atranorin exhibited a dose-dependent antioxidant activity in vitro, as assessed by total radical-trapping antioxidant parameter and total antioxidant reactivity assays. Uses: Antinociceptive/antiinflammatory/antibacterial. Synonyms: Atranoric acid; Atranorine; Parmelin; Usnarin; Benzoic acid, 3-formyl-2,4-dihydroxy-6-methyl-, 3-hydroxy-4-(methoxycarbonyl)-2,5-dimethylphenyl ester. Grade: 98%. CAS No. 479-20-9. Molecular formula: C19H18O8. Mole weight: 374.34.
Auraptenol
Auraptenol is a natural coumarin found in the fruits of Citrus aurantium. It has antifibrotic activity and the anti-hyperalgesic action which may be as a novel analgesic for the management of neuropathic pain. Uses: Antifibrotic, anti-hyperalgesic. Synonyms: (+)-8-(2-Hydroxy-3-methyl-3-butenyl)-7-methoxy-2H-1-benzopyran-2-one. Grade: >98%. CAS No. 1221-43-8. Molecular formula: C15H16O4. Mole weight: 260.3.
Aureobasidin A
Aureobasidin A is a cyclic depsipeptide antibiotic isolated from the filamentous fungus Aureobasidium pullulans R106. It is an antifungal agent that inhibits phosphorylceramide synthase. Synonyms: Basifungin. CAS No. 127785-64-2. Molecular formula: C60H92N8O11. Mole weight: 1101.42.
Auriculasin
Auriculasin is a flavonoid derivative isolated from the herbs of Derris robusta. Synonyms: Cudraisoflavone A. Grade: 96%. CAS No. 60297-37-2. Molecular formula: C25H24O6. Mole weight: 420.5.
Axinysone A
Axinysone A is a natural compound used in the research of cancer. Derived from natural sources, this product acts as a valuable inhibitor of specific signaling pathways involved in tumor growth and progression. Synonyms: (-)-Axinysone A. Grade: 97.5%. CAS No. 1114491-57-4. Molecular formula: C15H22O2. Mole weight: 234.338.
Ayanin
Ayanin isolated from the rhizomes of Curcuma aromatica. Synonyms: QUERCETIN 3,7,4'-TRIMETHYL ETHER; AYANIN; 2-(3-Hydroxy-4-methoxyphenyl)-3,7-dimethoxy-5-hydroxy-4H-1-benzopyran-4-one; 3',5-Dihydroxy-3,4',7-trimethoxyflavone; 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,7-dimethoxychromen-4-one. Grade: 0.985. CAS No. 572-32-7. Molecular formula: C18H16O7. Mole weight: 344.3.
Azacytidine-[13C5]
Labelled Azacytidine, produced by the strain of Streptoverticillium ladakanus var. ladakanus UC-2654. Azacitidine (Vidaza) is a chemotherapy drug used to treat conditions that affect the blood and the bone marrow, called myelodysplastic syndromes (MDS). It may also be used to treat other cancers, such as acute myeloid leukaemia (AML) or chronic myelomonocytic leukaemia (CMML). It reduces hypermethylation associated with certain diseases, including myelodysplastic syndromes (IC50s = 2.4 and 2.6 μM for in vitro anti-myeloma activity) and cancer (IC50s ~ 0.4 μM for inhibiting proliferation of various cancer cell lines). It can also act as a demethylating agent by inhibiting DNA methyltransferase. Synonyms: 4-Amino-1-[3,4-dihydroxy-5-(hydroxy(113C)methyl)(2,3,4,5-13C4)oxolan-2-yl]-1,3,5-triazin-2-one. Grade: 99%. Molecular formula: C3[13C]5H12N4O5. Mole weight: 249.17.
Azido-PEG4-alcohol
It is useful as a spacer and linker between compounds. Synonyms: Azido-PEG4-alcohol. Grade: ≥ 96 %. CAS No. 86770-67-4. Molecular formula: C8H17N3O4. Mole weight: 219.24.
Baccatin IX
Baccatin IX is extracted from the leaves and twigs of Taxus yunnanensis. Synonyms: 9-Dihydro-14-hydroxybaccatin III. CAS No. 1623410-12-7. Molecular formula: C31H40O12. Mole weight: 604.64.
Baccatin VIII
Baccatin VIII is extracted from the leaves and twigs of Taxus yunnanensis. It inhibits MCF-7 and HL-60 with IC50 values of 9.67 and 3.44 uM respectively. Synonyms: 9-Dihydro-14-hydroxy-13-O-acetylbaccatin III. Grade: 97.5%. CAS No. 1623410-10-5. Molecular formula: C33H42O13. Mole weight: 646.68.
Bacitracin A-[d7]
Labelled Bacitracin. Bacitracin is a mixture of related cyclic polypeptides produced by organisms of the licheniformis group of Bacillus subtilis var Tracy, which disrupts both gram positive and gram negative bacteria by interfering with cell wall and peptidoglycan synth. Grade: > 98%. Molecular formula: C66H96D7N17O16S. Mole weight: 1429.74.
Bacoside A3
Bacoside A is a mixture of chemical compounds, known as bacosides, isolated from Bacopa monnieri. Bacoside A3 is a triterpenoid saponin first isolated from B. monniera, which acts as a potential anticancer compound. Synonyms: Bacopa Pgp. Grade: ≥98%. CAS No. 157408-08-7. Molecular formula: C47H76O18. Mole weight: 929.1.
Baicalein
Baicalein (5,6,7-trihydroxyflavone) is a flavone, a type of flavonoid, originally isolated from the roots of Scutellaria baicalensis and Scutellaria lateriflora. Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor. Baicalein is a natural compound and can be used in cosmestics material. Uses: Neuroprotective; anticancer. Synonyms: 5,6,7-Trihydroxyflavone; 5,6,7-Trihydroxy-2-phenyl-4H-1-benzopyran-4-one; NSC 661431; Noroxylin; 5,6,7-Trihydroxy-2-phenyl-4H-1-benzopyran-4-one. Grade: ≥98%. CAS No. 491-67-8. Molecular formula: C15H10O5. Mole weight: 270.24.
Baicalin
Baicalin is a flavone found in several species in the genus Scutellaria, including Scutellaria baicalensis and Scutellaria lateriflora. Baicalin is a positive allosteric modulator of the benzodiazepine site and/or a non-benzodiazepine site of the GABA receptor. Baicalin can also absorb ultraviolet rays, scavenge oxygen free radicals, and inhibit the production of melanin. Therefore, it can be used in medicine and cosmetics. It is a good functional cosmetic raw material. Synonyms: Baicalin; 21967-41-9; Baicalein 7-O-glucuronide; 7-D-Glucuronic acid-5,6-dihydroxyflavone; Baicalein 7-glucuronide; CHEBI:2981; MFCD00134418; 347Q89U4M5; 5,6-dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yl beta-D-glucopyranosiduronic acid; 7-D-glucuronic acid-5,6-dihydroxy-flavone; CHEMBL485818; UNII-347Q89U4M5; 5,6,7-trihydroxyflavone 7-O-beta-D-glucuronide; Baicalein 7-O-.beta.-D-glucuronide; beta-D-Gl. Grade: 90%. CAS No. 21967-41-9. Molecular formula: C17H17ClN4. Mole weight: 320.8.
Bakkenolide B
Bakkenolide B is isolated from the leaves of Petasites japonicus and exhibits anti-allergic and anti-inflammatory effects. Synonyms: Fukinolide; (-)-Bakkenolide B. Grade: 95%. CAS No. 18455-98-6. Molecular formula: C22H30O6. Mole weight: 390.48.
Bakuchiol
Bakuchiol is a phytoestrogen isolated from the seeds of Psoralea corylifolia L with anti-tumor, antioxidant, and antibacterial effects. Bakuchiol has a retinol-like effect on skin gene expression and properties. Bakuchiol inhibits DNA polymerase and UDP-glucuronosyltransferase 2B7 (IC50 = 41 μM). Bakuchiol has hypoglycemic, hypolipidemic, anti-inflammatory, anti-wrinkle, soothing and liver protective, anticancer, antidepressant, and estrogen-like effects. Uses: Antioxidant. Synonyms: Drupanol; Chiba; NSC-671195; NSC671195; NSC 671195; UP-256; UP256; UP 256; W1975; W 1975; W-1975; 4-[(1E,3S)-3-Ethenyl-3,7-dimethyl-1,6-octadien-1-yl]phenol; Phenol, 4-(3-ethenyl-3,7-dimethyl-1,6-octadienyl)-, [S-(E)]-; Phenol, 4-[(1E,3S)-3-ethenyl-3,7-dimethyl-1,6-octadienyl]-; (+)-Bakuchiol; (S)-(+)-Bakuchiol; (S)-Bakuchiol; Bakutrol; Neuvachiol; Sytenol A. Grade: 98%. CAS No. 10309-37-2. Molecular formula: C18H24O. Mole weight: 256.38.
Baloxavir-[d4]
Baloxavir-[d4] is an isotope compound of Baloxavir. Baloxavir marboxil is a first-in-class, one-dose oral medicine with a novel proposed mechanism of action that has demonstrated efficacy in a wide range of influenza viruses, including in vitro activity against oseltamivir-resistant strains and avian strains (H7N9, H5N1) in non-clinical studies. Baloxavir is a polymerase acidic, cap-dependent, endonuclease inhibitor that is indicated for the treatment of acute uncomplicated influenza in patients aged 12 years and older who have been symptomatic for no more than 48 hours. It blocks viral proliferation by binding to one of two endonuclease binding sites, inhibiting the initiation of mRNA synthesis for both influenza A and influenza B strains. Baloxavir can interact with polyvalent cation-containing products, which can decrease its plasma concentration. CAS No. 2415027-80-2. Molecular formula: C24H15D4F2N3O4S. Mole weight: 487.51.
Baohuoside II
IKarisoside A is a natural compound isolated from Epimedium koreanum, which has anti-inflammatory properties. Uses: Cardioprotective effect. Synonyms: Icarisoside A. Grade: >98%. CAS No. 55395-07-8. Molecular formula: C26H28O10. Mole weight: 500.49.
Barnidipine-[d5]
Barnidipine-[d5] is a stable isotope form of Barnidipine which is a calcium channel blocker. Synonyms: 3-(3S)-1-[(D5)benzyl]pyrrolidin-3-yl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate; (S)-3-((S)-1-Benzylpyrrolidin-3-yl) 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate-d5. Molecular formula: C27H24D5N3O6. Mole weight: 496.57.
Bavachin
Bavachin, a natural phytoestrogen found in the fruits of Psoralea corylifolia L, potentially protects cartilage from inflammation-mediated damage in joints of osteoarthritis patients through decreasing IL-1β-induced activation of IKK-IκBα-NF-κB signaling pathway. Bavachin also exhibits the activities of antioxidant, antimutagenic and weak phytoestrogen by binding and activating the estrogen receptor. Synonyms: 4H-1-benzopyran-4-one, 2,3-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-6-(3-methyl-2-buten -1-yl)-; 7-Hydroxy-2-(4-hydroxyphenyl)-6-(3-methylbut-2-en-1-yl)-2,3-dihydro-4H-chromen -4-one. Grade: >98%. CAS No. 19879-32-4. Molecular formula: C20H20O4. Mole weight: 324.4.
Bavachinin
Bavachinin is a natural compound isolated from the Chinese herb Fructus Psoraleae. Bavachinin has potent anti-angiogenic activity in vitro and in vivo. Bavachinin inhibited increases in HIF-1α activity in human KB carcinoma (HeLa cell derivative) and human HOS osteosarcoma cells under hypoxia in a concentration-dependent manner, probably by enhancing the interaction between von Hippel-Lindau (VHL) and HIF-1α. It significantly inhibited Th2 cytokine production, including IL-4, IL-5 and IL-13. Notably, this compound almost completely blocked inflammation in the ovalbumin (OVA)-sensitized animal asthma model. Uses: Antiinflammatory; antipyretic; analgesic. Synonyms: 7-O-Methylbavachin; Bavachinin A. Grade: >98%. CAS No. 19879-30-2. Molecular formula: C21H22O4. Mole weight: 338.4.
Bellidifolin
Bellidifolin is a xanthone that can be isolated from the plants of Gentiana species. Study shows that bellidifolin is a potent hypoglycemic agent in streptozotocin (STZ)-induced diabetic rats from Swertia japonica. Bellidifolin may contribute to the protective effects associated with nerve injury initiated by hypoxia by mechanisms related to inhibition of cell apoptosis independent of the ERK pathway, but may involve blockade of p38MAPK signaling pathway activation and downstream caspase-3 expression. Synonyms: 1,5,8-Trihydroxy-3-methoxy-9H-xanthen-9-one. Grade: 98.5%. CAS No. 2798-25-6. Molecular formula: C14H10O6. Mole weight: 274.228.
Benzoylaconine
Benzoylaconine is an alkaloid in the Chinese traditional medicine Radix Aconiti Lateralis Preparata. Synonyms: Isaconitine; Pikraconitin. Grade: >98%. CAS No. 466-24-0. Molecular formula: C32H45NO10. Mole weight: 603.7.
Benzthiazuron-[d3]
Benzthiazuron-[d3] is a deuterium labelled Benzthiazuron, an herbicide used to control annual broad-leaved weeds in a variety of crops. Synonyms: Benzthiazuron-d3. Molecular formula: C9H6D3N3OS. Mole weight: 210.27.
Berberrubine
Berberrubine comes from the herbs of Coptis chinensis Franch. Berberrubine dose-dependently inhibited IL-8 and MCP-1 protein levels in the media and mRNA expression of the cells stimulated with IL-1beta or TNF-alpha. Uses: Antitumor/anti-diabetic. Synonyms: 5,6-Dihydro-9-hydroxy-10-methoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium chloride; 9-Berberoline chloride; 9-Demethoxy-9-hydroxyberberinium chloride; Berberrubine chloride; Beroline chloride; Chileninone; Nerberrubine. Grade: >98%. CAS No. 15401-69-1. Molecular formula: C19H16ClNO4. Mole weight: 357.79.
β-Aflatrem
β-Aflatrem is a class of structurally-diverse secondary metabolites isolated from Aspergillus flavus. It is a mycotoxin that exhibits insecticidal activity. Synonyms: Aflatrem B; Beta-Aflatrem; 4H-3,15a-Epoxy-1-benzoxepino(6',7':6,7)indeno(1,2-b)indol-4-one, 10-(1,1-dimethyl-2-propenyl)-2,3,5b,6,7,7a,8,13,13b,13c,14,15-dodecahydro-5b-hydroxy-2,2,13b,13c-tetramethyl-, (3alpha,5balpha,7abeta,13balpha,13cbeta,15aalpha)-(+)-. Grade: ≥98%. CAS No. 144446-23-1. Molecular formula: C32H39NO4. Mole weight: 501.66.
β-Aspartylaspartic acid TFA salt
An impurity of L-Ornithine L-aspartate salt which is used as a ligand in targeting SDF-1/CXCL12 with ligands that prevents activation of CXCR4 through structure-based drug design. Synonyms: β-Aspartylaspartic acid TFA; β-Aspartylaspartic acid trifluoroacetate salt; beta-Asp-Asp TFA salt; (2S)-2-[[(3S)-3-amino-3-carboxypropanoyl]amino]butanedioic acid trifluoroacetate salt. Molecular formula: C10H13F3N2O9. Mole weight: 362.21.
Betulinic acid
Betulinic acid is a pentacyclic lupane-type triterpene derivative of betulin with antiinflammatory, anti-HIV and antineoplastic activities. Betulinic acid induces apoptosis through induction of changes in mitochondrial membrane potential, production of reactive oxygen species, and opening of mitochondrial permeability transition pores, resulting in the release of mitochondrial apogenic factors, activation of caspases, and DNA fragmentation. Betulinic acid is a natural compound found in the herbs of Ziziphus jujuba. It can be used in cosmetics material. Uses: Anti-melanogenic/antitumor/anti-hiv. Synonyms: ALS357; ALS 357; ALS-357; Mairin; Lupatic Acid; 3beta-Hydroxy-20(29)-lupaene-28-oic acid. Grade: 98%. CAS No. 472-15-1. Molecular formula: C30H48O3. Mole weight: 456.70.
Biapigenin
It is isolated from the herbs of Hypericum perforatum L. Synonyms: [3,8'-Bi-4H-1-benzopyran]-4,4'-dione, 5,5',7,7'-tetrahydroxy-2,2'-bis(4-hydroxyphenyl)-; 5,5',7,7'-Tetrahydroxy-2,2'-bis(4-hydroxyphenyl)[3,8'-bi-4H-1-benzopyran]-4,4'-dione; 3,8''-Biapigenin; 8,3''-Biapigenin; I3,II8-Biapigenin. Grade: 98%. CAS No. 101140-06-1. Molecular formula: C30H18O10. Mole weight: 538.46.
Bifenox-[d3]
Bifenox-[d3] is a labelled compound of Bifenox which is a herbicide. Synonyms: Bifenox-d3 (2,4-dichlorophenoxy-d3); 5-(2,4-Dichlorophenoxy)-2-nitrobenzoic Acid Methyl Ester-d3; 2,4-Dichlorophenyl 3-(Methoxycarbonyl)-4-nitrophenyl Ether-d3; Methyl 5-(2,4-Dichlorophenoxy)-2-nitrobenzoate. Grade: > 98%. Molecular formula: C14H6D3Cl2NO5. Mole weight: 345.15.
Bi-linderone
Bi-linderone is a natural miscellaneou found in the roots of Lindera aggregata( Sims) Kosterm, it shows significant activity against glucosamine-induced insulin resistance in HepG2 cells at a concentration of 1 microg/mL. Grade: >95%. CAS No. 1227375-09-8. Molecular formula: C34H32O10. Mole weight: 600.6.
Bilobalide
Bilobalide is a biologically active terpenic trilactone present in Ginkgo biloba. Synonyms: (-)-Bilobalide; Vitexicarpim; (3aS,5aR,8aS)-9R-(1,1-dimethylethyl)-10,10aS-dihydro-8R,9-dihydroxy-4H,5aH,9H-furo[2,3-b]furo[3',2':2,3]cyclopenta[1,2-c]furan-2,4,7(3H,8H)-trione. Grade: >98%. CAS No. 33570-04-6. Molecular formula: C15H18O8. Mole weight: 326.30.
Biorobin
Biorobin is a natural flavonoid found in the herbs of Cassia occidentalis. Synonyms: 3-[[6-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-galactopyranosyl]oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; Kaempferol 3-O-robinoside. Grade: >98%. CAS No. 17297-56-2. Molecular formula: C27H30O15. Mole weight: 594.53.
Bisabola-3,10-dien-2-one
Bisabola-3,10-dien-2-one is isolated from the leaves of Alpinia intermedia. Synonyms: 1-Bisabolone; 6R,7R-Bisabolone; (6R)-3-methyl-6-[(2S)-6-methylhept-5-en-2-yl]cyclohex-2-en-1-one. Grade: 98.0%. CAS No. 61432-71-1. Molecular formula: C15H24O. Mole weight: 220.356.
Bisandrographolide A
Bisandrographolide A is a natural diterpenoid found in the herbs of Andrographis paniculata (Burm. f.) Nees. The compound can activate TRPV4 channels and play a role in some of the effects of Andrographis extract described in traditional medicine. Synonyms: bisandrographolide. Grade: >96%. CAS No. 160498-00-0. Molecular formula: C40H56O8. Mole weight: 664.88.
BKT140
BKT140 is a CXCR4 inhibitor with antineoplastic activity. Studies demonstrated that BKT140 showed a robust mobilization of white blood cells (WBC) and hematopoietic stem cells (HSC). Synonyms: BL-8040; Motixafortide; 4F-benzoyl-TN14003. Grade: 98%. CAS No. 664334-36-5. Molecular formula: C97H144FN33O19S2. Mole weight: 2159.55.
Boc-Gly-Gly-Phe-Gly-OH is a self-assembly of N- and C-protected tetrapeptide. It is also a protease-cleavable linker for antibody-drug conjugates (ADCs). Synonyms: N-tert-butoxycarbonyl-glycyl-glycyl-L-phenylalanyl-glycine; N-(tert-butoxycarbonyl)-glycylglycyl-L-phenylalanylglycine; (S)-12-Benzyl-2,2-dimethyl-4,7,10,13-tetraoxo-3-oxa-5,8,11,14-tetraazahexadecan-16-oic acid. Grade: >95%. CAS No. 187794-49-6. Molecular formula: C20H28N4O7. Mole weight: 436.46.
Boc-GRR-AMC TFA
Boc-GRR-AMC (TFA) is a tri-peptide Substrate. BOC-GRR-AMC is cleaved by type II Metacaspases Atmc4 and Atmc9 of Arabidopsis thaliana. It is a substrate for flavivirus proteases such as West Nile virus protease, yellow fever virus NS3 protease, and dengue virus NS2B-NS3 protease. Grade: 98%. Molecular formula: C29H44N10O7.xC2HF3O2. Mole weight: 644.72 (free base).
Boc-His(Trt)-Aib-OH
Boc-His(Trt)-Aib-OH, a highly specialized peptide synthesis reagent employed within the biomedical industry, presents a powerful capability for the creation of peptide sequences inclusive of unconventional amino acids. Its steadfast utilization helps to promote the generation of distinct and optimal peptide architectures, critical for the progression of targeted drug development, including the likes of Alzheimer's disease, cancer and many other diseases. Synonyms: (S)-2-(2-((tert-Butoxycarbonyl)amino)-3-(1-trityl-1H-imidazol-4-yl)propanamido)-2-methylpropanoic acid. CAS No. 2061897-68-3. Molecular formula: C34H38N4O5. Mole weight: 582.7.
Boc-L-beta-homoalanine
Boc-L-beta-homoalanine, a noteworthy derivative of beta-homoalanine, serves as an essential constituent in the production of peptides and mimics. Its effectivity as a medicinal substance, especially with reference to treating devastating afflictions like Parkinson's, Alzheimer's, and multiple sclerosis, has been the focal point of discussion in relevant studies. Synonyms: (S)-3-((tert-Butoxycarbonyl)amino)butanoic acid; Boc-beta-HoAla-OH; Butanoic acid, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-, (3S)-. Grade: 95%. CAS No. 158851-30-0. Molecular formula: C9H17NO4. Mole weight: 203.24.
Boc-LRR-AMC (trifluoroacetate salt)
Boc-LRR-AMC is a fluorogenic substrate for the trypsin-like activity of the 26S proteasome or 20S proteolytic core. Synonyms: Boc-Leu-Arg-Arg-AMC.TFA; N-[(1,1-dimethylethoxy)carbonyl]-L-leucyl-L-arginyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-argininamide, trifluoroacetate salt. Grade: 95%. Molecular formula: C35H53F3N10O9. Mole weight: 814.87.
Boc-L-serine tert-butyl ester
Boc-L-serine t-butyl ester is a modified and protected amino acid used in peptide synthesis. Synonyms: Boc-L-Ser-OtBu; Boc-L-β-hydroxyalanine tert-butyl ester; (S)-tert-Butyl 2-((tert-butoxycarbonyl)amino)-3-hydroxypropanoate. Grade: ≥ 98%. CAS No. 7738-22-9. Molecular formula: C12H23NO5. Mole weight: 261.32.
A Boc PNA monomer that is a building block for the synthesis of PNA oligomers. Synonyms: Boc-C(Z)-Aeg-OH; N-(2-(4-(((Benzyloxy)carbonyl)amino)-2-oxopyrimidin-1(2H)-yl)acetyl)-N-(2-((tert-butoxycarbonyl)amino)ethyl)glycine. Grade: 95%. CAS No. 144564-94-3. Molecular formula: C23H29N5O8. Mole weight: 503.51.
BOC-VAL-PRO-ARG-MCA TFA salt
BOC-VAL-PRO-ARG-MCA is a specific, highly fluorogenic substrate for thrombin and the thrombin-staphylocoagulase complex. Synonyms: Boc-Val-Pro-Arg-4-methylcoumaryl-7-amide TFA salt; Boc-Val-Pro-Arg-4-methyl-7-coumarylamide TFA salt. Molecular formula: C33H46F3N7O9. Mole weight: 741.76.
Boehmenan
Boehmenan is a natural lignan found in the herbs of Euphorbia hirta Linn, it inhibits PTP1B activity in a competitive manner and may also inhibit the Wnt signal by decreasing β-catenin levels. Synonyms: 3-(4-Hydroxy-3-methoxyphenyl)propenoic acid 3-[2,3-dihydro-2-(4-hydroxy-3-methoxyphenyl)-3-[[[3-(4-hydroxy-3-methoxyphenyl)-1-oxo-2-propenyl]oxy]methyl]-7-methoxybenzofuran-5-yl]propyl ester. Grade: >97%. CAS No. 57296-22-7. Molecular formula: C40H40O12. Mole weight: 712.8.
Boeravinone B
Boeravinone B isolated from the roots of Boerhaavia coccinea. Synonyms: 10-Methyl-6,9,11-trihydroxy[1]benzopyrano[3,4-b][1]benzopyran-12(6H)-one. Grade: 0.98. CAS No. 114567-34-9. Molecular formula: C17H12O6. Mole weight: 312.3.
Boeravinone E
Boeravinone E is isolated from the herbs of Mirabilis jalapa. Synonyms: 3,6,9,11-Tetrahydroxy-10-methyl[1]benzopyrano[3,4-b][1]benzopyran-12(6H)-one. Grade: 98%. CAS No. 137787-00-9. Molecular formula: C17H12O7. Mole weight: 328.27.
Bonducellpin D
Bonducellpin D is a natural diterpenoid compound found in several plants. . Synonyms: (3bS,3b1R,5aR,6S,6aR,10S,10aS,10bS)-6a,10-dihydroxy-7,7,10a-trimethyl-4-oxo-3b,3b1,5a,6,6a,7,8,9,10,10a,10b,11-dodecahydro-4H-phenanthro[3,2-b:10,1-b'c']difuran-6-yl acetate; (+)-Bonducellpin D. Grade: >95%. CAS No. 197781-85-4. Molecular formula: C22H28O7. Mole weight: 404.45.
Borapetoside B
Borapetoside B is isolated from Tinospora. Uses: Hypoglycemic. Synonyms: methyl (2S,4aS,6S,6aR,9R,10aS,10bS)-2-(furan-3-yl)-9-hydroxy-6a,10b-dimethyl-4-oxo-6-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-1,4,4a,5,6,6a,9,10,10a,10b-decahydro-2H-benzo[f]isochromene-7-carboxylate. Grade: 95%. CAS No. 104901-05-5. Molecular formula: C27H36O12. Mole weight: 552.568.
Borapetoside E
Borapetoside E is isolated from Tinospora. Synonyms: 1,4-Methano-2-benzoxepin-9-carboxylic acid, 5-[(2S)-2-(3-furanyl)-2-(β-D-glucopyranosyloxy)ethyl]-1,3,4,5,5a,6,7,9a-octahydro-5,9a-dimethyl-3-oxo-, methyl ester, (1S,4R,5S,5aS,9aR)-; Methyl (1S,2R,7S,8S,9R)-8-[(2S)-2-(3-furyl)-2-(β-D-glucopyranosyloxy)ethyl]-2,8-dimethyl-10-oxo-11-oxatricyclo[7.2.1.02,7]dodec-3-ene-3-carboxylate. Grade: 95%. CAS No. 151200-49-6. Molecular formula: C27H36O11. Mole weight: 536.57.
Borapetoside F
Borapetoside F is isolated from Tinospora. Synonyms: 2H-Naphtho[2,1-c]pyran-7-carboxylic acid, 2-(3-furanyl)-6-(β-D-glucopyranosyloxy)-1,4,6,6a,9,10,10a,10b-octahydro-6a,10b-dimethyl-4-oxo-, methyl ester, rel-(2R,6R,6aS,10aR,10bR)-(+)-; 2H-Naphtho[2,1-c]pyran-7-carboxylic acid, 2-(3-furanyl)-6-(β-D-glucopyranosyloxy)-1,4,6,6a,9,10,10a,10b-octahydro-6a,10b-dimethyl-4-oxo-, methyl ester, (2α,6β,6aβ,10aβ,10bα)-(+)-; rel-Methyl (2R,6R,6aS,10aR,10bR)-(+)-2-(3-furanyl)-6-(β-D-glucopyranosyloxy)-1,4,6,6a,9,10,10a,10b-octahydro-6a,10b-dimethyl-4-oxo-2H-naphtho[2,1-c]pyran-7-carboxylate. Grade: 95%. CAS No. 151200-50-9. Molecular formula: C27H34O11. Mole weight: 534.55.
Boswellic acid
α-Boswellic acid, a pentacyclic triterpene molecule, is isolated from the herbs of Boswellia carterii Birdw. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: (18β)-3α-Hydroxygermanica-12-ene-24-oic acid; (4R)-3α-Hydroxyolean-12-en-24-oic acid. Grade: 98%. CAS No. 471-66-9. Molecular formula: C30H48O3. Mole weight: 456.7.
Brazzein
Brazzein is a sweet-tasting protein composed of 54 amino acids and is considered as a potential sugar substitute. Uses: Brazzein, a natural sweet protein derived from the fruit of the west african plant pentadiplandra brazzeana, has garnered significant attention in recent years for its potential applications in drug discovery. this unique protein, which is approximately 2,000 times sweeter than sucrose on a weight basis, possesses several properties that make it a promising candidate for various pharmaceutical and. Grade: 90%. Mole weight: 6473.
Brevianamide F
Brevianamide F, belongs to a class of naturally occurring 2,5-diketopiperazines, is produced by the fungi A.fumigates and Aspergillus sp. Synonyms: Cyclo-L-Trp-L-Pro; L-prolyl-L-tryptophan. Grade: ≥95%. CAS No. 38136-70-8. Molecular formula: C16H17N3O2. Mole weight: 283.33.
Brevilin A
Brevilin A, also called 6-O-Angeloylplenolina, is a natural sesquiterpenoid found in the herbs of Centipeda minima, it exhibits the antigiardial activity (IC50 = 16.1 μM) and is similarly active in vitro against Entamoeba histolytica (IC50 between 4.5 and 9 μM) and against Plasmodium falciparum (IC50 = 9.42 μM). Brevilin A inhibits janus kinase activity and exhibits both strong STAT3 signal inhibition and STAT3 signal dependent cell growth inhibition. Uses: Anti-giardial. Synonyms: 6-O-Angeloylplenolin. Grade: >91%. CAS No. 16503-32-5. Molecular formula: C20H26O5. Mole weight: 346.4.
Britannilactone
A bioassay-guided isolation of the chloroform fraction of the I. britannica using an in vitro melanogenesis inhibition assay led to the isolation of sesquiterpenes, 1-O-acetylbritannilactone (1), britannilactone (2) and neobritannilactone B (3). Compounds 1 and 2 significantly reduced melanin production in a dose-dependent manner with IC50 values of 13.3 and 15.5 μM, respectively. Synonyms: Desacetylinulicin. Grade: >98%. CAS No. 33620-72-3. Molecular formula: C15H22O4. Mole weight: 266.33.
Bromuron-[d6]
Bromuron-[d6] is a deuterium labelled Bromuron, a urea herbicide. Synonyms: Bromuron-d6. Molecular formula: C9H5D6BrN2O. Mole weight: 249.14.
Broussonin B
Broussonin B is a natural phenols found in the branch of Broussonetia papyrifera, it has moderate inhibitory activities against a chymotrypsin-like activity of the proteasome. Synonyms: 4-[3-(4-Hydroxyphenyl)propyl]-3-methoxyphenol. Grade: >98%. CAS No. 73731-86-9. Molecular formula: C16H18O3. Mole weight: 258.32.
Broussonin C
Broussonin C is a natural phenol found in the branch of Broussonetia papyrifera, it exerts simple reversible slow-binding inhibition against diphenolase. Synonyms: 4-[3-[4-Hydroxy-3-(3-methyl-2-butenyl)phenyl]propyl]-1,3-benzenediol; 1,3-Benzenediol,4-[3-[4-hydroxy-3-(3- Methyl-2-butenyl)phenyl]propyl]-. Grade: >98%. CAS No. 76045-49-3. Molecular formula: C20H24O3. Mole weight: 312.41.
Bruceine D
Bruceine D is extracted from the barks of Ailanthus altissima. It is an inhibitor of hepatocellular carcinoma growth and inhibits the growth of three pancreatic cancer cell lines, which acts by targeting β-catenin/jagged1 pathways. It also induces cytotoxicity in Capan-2 cells by inducing cellular apoptosis involving the mitochondrial pathway. It may be used as a lead compound for new viricides, or a natural viricide. Synonyms: Nsc318801; (1beta,11beta,12alpha,15beta)-13,20-Epoxy-1,11,12,14,15-pentahydroxypicras-3-ene-2,16-dione; Picras-3-ene-2,16-dione,13,20-epoxy-1,11,12,14,15-pentahydroxy-, (1b,11b,12a,15b)-; (1R,2S,3R,3aR,3a1R,4R,6aR,7aS,11S,11aS)-1,2,3a,4,11-pentahydroxy-3,8,11a-trimethyl-1,2,3,3a,4,7,7a,11,11a,11b-decahydro-5H-3,3a1-(epoxymethano)dibenzo[de,g]chromene-5,10(6aH)-dione. Grade: 98.5%. CAS No. 21499-66-1. Molecular formula: C20H26O9. Mole weight: 410.42.
Bruceine E
Bruceine E is extracted from the seeds of Brucea javanica (L.) Merr. It could reduce blood glucose concentration remarkably and may be used as an insulin secretagogue. Synonyms: 13,20-Epoxy-1β,2α,11β,12α,14,15β-hexahydroxypicras-3-en-16-one; 20-Deoxybruceine F; 2-O-Demethylbruceine M; 5H-3,11c-beta-(Epoxymethano)phenanthro(10,1-bc)pyran-5-one, 1,2,3,3a,4,6a-beta,7,7a-alpha,10,11,11a,11b-alpha-dodecahydro-1-beta,2-alpha,3a-beta,4-beta,10-alpha,11-beta-hexahydroxy-3-alpha,8,11a-beta-trimethyl-, (+)-; Picras-3-en-16-one, 13,20-epoxy-1,2,11,12,14,15-hexahydroxy-, (1beta,2alpha,11beta,12alpha,15beta)-. Grade: 98.0%. CAS No. 21586-90-3. Molecular formula: C20H28O9. Mole weight: 412.43.
Bryonamide A
Bryonamide A is an alkaloid isolated from Bryonia aspera. Synonyms: 4-Hydroxy-N-(2-hydroxyethyl)benzamide; N-(2-Hydroxyethyl)-4-hydroxybenzamide; Benzamide, 4-hydroxy-N-(2-hydroxyethyl)-. Grade: 98.5%. CAS No. 75268-14-3. Molecular formula: C9H11NO3. Mole weight: 181.191.