BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
Trisulfide Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: DPhe-Cys-Phe-DTrp-Lys-Thr-Cys-Thr-ol(Cys2&Cys7 Trisulfide bridge); Octreotide EP Impurity E; D-Phenylalanyl-S-sulfanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-L-threoninol cyclic (2→7)-trisulfide; D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr-ol (Trisulfide Bridge between Cys2-Cys7); D-Phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cystyl-L-threoninol (Trisulfide Bridge between Cys2-Cys7); Octreotide impurity E; DPhe-CF-DTrp-KTC-Thr-ol(Cys2&Cys7 Trisulfide bridge). Grade: ≥95%. CAS No. 1546983-27-0. Molecular formula: C49H66N10O10S3. Mole weight: 1051.31.
Tropodithietic acid
Tropodithietic acid (TDA) is a broad-spectrum antibiotic produced by the marine bacterium Roseobacter gallaeciensis. It is effective against a variety of Gram-negative α-proteobacteria, γ-proteobacteria, and flavobacteria as well as Gram-positive actinobacteria strains in a disc assay. Synonyms: TDA. Grade: ≥98%. CAS No. 750590-18-2. Molecular formula: C8H4O3S2. Mole weight: 212.25.
Tropolone
A bactericidal antibiotic composed of a seven membered aromatic ring. Synonyms: Purpurocatechol. Grade: ≥ 99 %. CAS No. 533-75-5. Molecular formula: C7H6O2. Mole weight: 122.12.
TRV-120027
Synthetic analogue of endogenous peptide angiotensin II. An investigational drug for the treatment of heart failure and kidney disease. Synonyms: (2R)-2-[[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[2-(methylamino)acetyl]amino]pentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carbonyl]amino]propanoic acid. CAS No. 1234510-46-3. Molecular formula: C43H67N13O10. Mole weight: 926.1.
TRV-120027 acetate
TRV-120027 acetate, a β-arrestin-1-biased agonist of the angiotensin II receptor type 1 (AT1R), engages β-arrestins while blocking G-protein signaling. TRV-120027 inhibits angiotensin II-mediated vasoconstriction and increases cardiomyocyte contractility. TRV-120027 has the potential for acute decompensated heart failure (ADHF) treatment. Synonyms: H-Sar-Arg-Val-Tyr-Ile-His-Pro-D-Ala-OH.CH3CO2H; sarcosyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-D-alanine acetic acid; D-Alanine, N-methylglycyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-, acetate (1:1); TRV 027 acetate; TRV 120027 acetate; TRV120027 acetate. Grade: ≥95%. Molecular formula: C45H71N13O12. Mole weight: 986.14.
TRV-120027 TFA
TRV120027 TFA, a β-arrestin-1-biased agonist of the angiotensin II receptor type 1 (AT1R), engages β-arrestins while blocking G-protein signaling. TRV120027 TFA inhibits angiotensin II-mediated vasoconstriction and increases cardiomyocyte contractility. TRV120027 TFA has the potential for the acute decompensated heart failure (ADHF) treatment. Synonyms: H-Sar-Arg-Val-Tyr-Ile-His-Pro-D-Ala-OH.TFA; sarcosyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-D-alanine trifluoroacetate; D-Alanine, N-methylglycyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-, trifluoroacetate (1:1); TRV 027 trifluoroacetate; TRV 120027 trifluoroacetate; TRV120027 trifluoroacetate; TRV120027 TFA; TRV 120027 TFA. Grade: 99%. Molecular formula: C45H68F3N13O12. Mole weight: 1040.10.
Trypacidin
It is produced by the strain of Aspergillus fumigatus. Trypacidin has anti-protozoal and spirochete effects, but the effect on the latter is weak. Synonyms: BRN 1299866; Methyl 4,6'-dimethoxy-6-methyl-3,4'-dioxo-3H-spiro[1-benzofuran-2,1'-cyclohexa[2,5]diene]-2'-carboxylate. Grade: ≥98% by HPLC. CAS No. 1900-29-4. Molecular formula: C18H16O7. Mole weight: 344.31.
Tryptanthrin
Tryptanthrin is a potent inhibitor of Cox-2, IDO and NOS II produced by the strain of Candida lipolytica CBS2070 2072 and it has the effect of resisting gram positive bacteria. Synonyms: Tryptanthrine; NSC 349447; Indolo(2,1-b)quinazoline-6,12-dione (8CI)(9CI). Grade: ≥98%. CAS No. 13220-57-0. Molecular formula: C15H8N2O2. Mole weight: 248.24.
TT-232
TT 232 is a somatostatin analog that acts as a peptide agonist for sst1/sst4 somatostatin receptors. TT 232 inhibits tyrosine kinase activity in human colon tumor cell lines. TT 232 was shown to suppress proliferation and induce apoptosis in a pancreatic tumor cell line. Synonyms: TT2-32; TT2 32; TT232; TT-232; TT 232; CAP 232; CAP-232; CAP232. CAS No. 147159-51-1. Molecular formula: C45H58N10O9S2. Mole weight: 947.13.
TT-232 TFA
TT-232 TFA is a somatostatin analog that acts as a peptide agonist for sst1/sst4 somatostatin receptors. TT-232 TFA inhibits tyrosine kinase activity in human colon tumor cell lines. TT-232 TFA was shown to suppress proliferation and induce apoptosis in a pancreatic tumor cell line. Synonyms: H-D-Phe-Cys-Tyr-D-Trp-Lys-Cys-Thr-NH2.TFA (Disulfide bridge: Cys2-Cys6); D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-cysteinyl-L-threoninamide (2->6)-disulfide trifluoroacetic acid; CAP 232 TFA; TLN 232 TFA; TT 2-32 TFA. Grade: ≥95%. CAS No. 2703745-48-4. Molecular formula: C45H58N10O9S2.C2HF3O2. Mole weight: 1061.16.
Tubercidin
Tubercidin is an adenosine analog with antiviral, antitrypanosomal, and antifungal properties. It inhibits DNA/RNA synthesis and other metabolic processes. Uses: 7-deaza-adenosine is an adenosine analog. Synonyms: 7-Deazaadenosine; Antibiotic XK 101-1; BRN 0038498; 7-Deaza ribo Adenosine; 7-β-D-Ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine; 4-Amino-7-(β-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine; 6-Amino-9-D-ribofuranosyl-7-desazapurine; N7-Deazaadenosine; NQZ-003; NSC 56408; Sparsamycin A; Sparsomycin A; Tubercidine; U 10071. Grade: ≥98% by HPLC. CAS No. 69-33-0. Molecular formula: C11H14N4O4. Mole weight: 266.25.
Tubermycin B
A simple phenazine produced by several species of pseudomonas and actinomycetes. It is a weakly active antibacterial compound that plays a role in the biocontrol of plant diseases by several pseudomonas strains. Synonyms: 1-Phenazinecarboxylic acid; 1-Carboxylic acid phenazine; NRRL B-1576; NSC 15851; BRN 0183818. Grade: >98% by HPLC. CAS No. 2538-68-3. Molecular formula: C13H8N2O2. Mole weight: 224.21.
Tubulysin A
Tubulysin A is a novel antibiotic, which exhibits anti-microtubule, anti-mitotic, apoptosis inducer, anticancer, anti-angiogenic, and antiproliferative activity. Tubulysins show very high cytotoxic activity against in vitro and in in vivo tumor models, especially against resistant tumor cell lines. Many representatives of these natural products are several orders of magnitude more potent than other available chemotherapeutics. Uses: Adcs cytotoxin. Synonyms: TubA; (αS,γR)-γ-[[[2-[(1R,3R)-1-(Acetyloxy)-4-methyl-3-[[(2S,3S)-3-methyl-2-[[[(2R)-1-methyl-2-piperidinyl]carbonyl]amino]-1-oxopentyl][(3-methyl-1-oxobutoxy)methyl]amino]pentyl]-4-thiazolyl]carbonyl]amino]-4-hydroxy-α-methyl-benzenepentanoic Acid. Grade: ≥95% by HPLC. CAS No. 205304-86-5. Molecular formula: C43H65N5O10S. Mole weight: 844.07.
Tubulysin B
Tubulysin B is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates. It also has anti-fungal properties. Synonyms: (2S,4R)-2-Methyl-4-[2-[(1R,3R)-1-acetoxy-3-[[N-[[(2R)-1-methyl-2beta-piperidinyl]carbonyl]-L-isoleucyl](butanoyloxymethyl)amino]-4-methylpentyl]thiazole-4-ylcarbonylamino]-5-(4-hydroxyphenyl)pentanoic acid. Grade: ≥95%. CAS No. 205304-87-6. Molecular formula: C42H63N5O10S. Mole weight: 830.04.
Tubulysin C
Tubulysin C is a highly cytotoxic peptide isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis. Tubulysin C is a cytotoxic activity tubulysin which inhibits tubulin polymerization and leads to cell cycle arrest and apoptosis. Synonyms: Tubulysin C; 205304-88-7; 072P54KU0L; UNII-072P54KU0L; (2S,4R)-4-[[2-[(1R,3R)-1-acetyloxy-4-methyl-3-[[(2S,3S)-3-methyl-2-[[(2R)-1-methylpiperidine-2-carbonyl]amino]pentanoyl]-(propanoyloxymethyl)amino]pentyl]-1,3-thiazole-4-carbonyl]amino]-5-(4-hydroxyphenyl)-2-methylpentanoic acid; Benzenepentanoic acid, gamma-(((2-((1R,3R)-1-(acetyloxy)-4-methyl-3-(((2S,3S)-3-methyl-2-((((2R)-1-methyl-2-piperidinyl)carbonyl)amino)-1-oxopentyl)((1-oxopropoxy)methyl)amino)pentyl)-4-thiazolyl)carbonyl)amino)-4-hydroxy-alpha-methyl-, (alphaS. ga; SCHEMBL24218753; EX-A5466C; HY-N2347; AKOS040740942; CS-0021784; BENZENEPENTANOIC ACID. GAMMA.-(((2-((1R,3R)-1-(ACETYLOXY)-4-METHYL-3-(((2S,3S)-3-METHYL-2-((((2R)-1-METHYL-2-PIPERIDINYL)CARBONYL)AMINO)-1-OXOPENTYL)((1-OXOPROPOXY)METHYL)AMINO)PENTYL)-4-THIAZOLYL)CARBONYL)AMINO)-4-HYDROXY-.ALPHA.-METHYL-, (.ALPHA.S. GAMMA.R)-. Grade: 98%. CAS No. 205304-88-7. Molecular formula: C41H61N5O10S. Mole weight: 816.02.
Tubulysin D
Tubulysin D is a tetrapeptide isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis. It displays potent antitumor activity and leads to cell cycle arrest and apoptosis by inhibiting tubulin polymerization with an IC50 of 1.7 μM. Tubulysin displays extremely potent cytotoxic activity in mammalian cells, including multidrug-resistant cell lines, with IC50 values in the lower nanomolar range. Synonyms: (+)-Tubulysin D. Grade: ≥98%. CAS No. 309935-57-7. Molecular formula: C43H65N5O9S. Mole weight: 828.07.
Tuftsin
Tuftsin is a tetrapeptide located in the Fd fragment of the gamma-globulin molecule. Tuftsin is a macrophage/microglial activator. Synonyms: L-Arginine, L-threonyl-L-lysyl-L-prolyl-; L-Arginine, N2-[1-(N2-L-threonyl-L-lysyl)-L-prolyl]-; L-Threonyl-L-lysyl-L-prolyl-L-arginine; Tafcine; Taftsin; Taphcin; H-Thr-Lys-Pro-Arg-OH. Grade: 95%. CAS No. 9063-57-4. Molecular formula: C21H40N8O6. Mole weight: 500.59.
Tulathromycin A is a triamilide antibiotic used for the treatment of bovine and porcine respiratory disease. It exists as an equilibrium mixture of two isomeric forms, Tulathromycin A (90%) and B (10%). Uses: Anti-bacterial agents. Synonyms: Tulathromycin; Draxxin; (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[[2,6-Dideoxy-3-C-methyl-3-O-methyl-4-C-[(propylamino)methyl]-α-L-ribo-hexopyranosyl]oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one; CP 472295; Increxxa; Lydaxx; Traxovet; Tulathrin; Tulaven; Tulinovet; Tulissin. Grade: 98% by HPLC. CAS No. 217500-96-4. Molecular formula: C41H79N3O12. Mole weight: 806.08.
Tumor Necrosis Factor-α human
Tumor necrosis factor-α (TNF-α) is a mononuclear macrophage-derived cytokine with in vivo anti-tumor properties and in vitro cytotoxicity to some transformed cell lines. TNF-α is a bifunctional growth regulator that can promote the growth of a variety of cells. TNF-α belongs to the TNF family of ligands and signals through two receptors, TNFR1 and TNFR2. TNF-α is a pleiotropic pro-inflammatory cytokine that plays a role in antitumor activity, immunomodulation, inflammation, anorexia, cachexia, septic shock, viral replication, and hematopoiesis. Synonyms: Cachectin; Cytotoxin; Differentiation-inducing factor (DIF); Necrosin; Tumor Necrosis Factor; TNF-alpha/TNFSF2 Protein, Human; Tumor necrosis factor (human); 1-157-Tumor necrosis factor alfa-1a (human); Beromun; Tasonermin; TNF-α human; hTNF-α; TNF-α. Grade: ≥95%. CAS No. 94948-59-1. Mole weight: ~17.4 kDa.
Tung oil, polymer with bisphenol A, epichlorohydrin and Me linoleate
Tung oil, polymer with bisphenol A, epichlorohydrin and Me linoleate. Grade: 95%. CAS No. 68648-75-9.
Tunicamycin
Tunicamycin, a mixture of homologous nucleoside antibiotics, has been used to study the effect of N-linked glycosylation of human proton-coupled folate transporter (HsPCFT) in HeLa cells. Tunicamycin blocks the formation of N-glycosidic linkages by inhibiting the first step in glycoprotein synthesis. It exhibits a range of biological activities, including antimicrobial, antivirus, and antitumor effects. It is produced by certain bacteria, including Streptomyces lysosuperficus and Streptomyces chartreusis. Grade: ≥98%. CAS No. 11089-65-9.
Tylosin
Tylosin is a 16-member-ring macrolide produced through the fermentation of Streptomyces fradiae, a species of actinobacteria found in soil. It is effective against gram-positive bacteria, Mycoplasma species and certain gram-negative bacteria. With other macrolides, tylosin inhibits protein synthesis by binding to the 50S subunit of the bacterial ribosome and disrupting aminoacyl-and peptidyl-tRNA transcription. This is believed to ultimately prevent the bacteria from reproducing. Synonyms: Tylosine; Tylocine; Tylosinum; Fradizine; NSC758961; (10E,12E)-(3R,4S,5S,6R,8R,14S,15R)-14-((6-deoxy-2,3-di-O-methyl-beta-D-allopyranosyl)oxymethyl)-5-((3,6-dideoxy-4-O-(2,6-dideoxy-3-C-methyl-alpha-L-ribo-hexopyranosyl)-3-dimethylamino-beta-D-glucopyranosyl)oxy)-6-formylmethyl-3-hydroxy-4,8,12-trimethyl-9-oxoheptadeca-10,12-dien-15-olide. Grade: >98%. CAS No. 1401-69-0. Molecular formula: C46H77NO17. Mole weight: 916.10.
Tylosin A
A highly purified form of tylosin A. It is a macrolide antibiotic, which is considered to be the major component of tylosin (comprises approximately 90% of tylosin). However, tylosins B, C and D contribute to the overall potency of tylosin. Synonyms: Tylosin; [4R-(4R*,5S*,6S*,7R*,9R*,11E,13E,15R*,16R*)]-15-[[(6-Deoxy-2,3-di-O-methyl-β-D-allopyranosyl)oxy]methyl]-6-[[3,6-dideoxy-4-O-(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)-3-(dimethylamino)-β-D-glucopyranosyl]oxy]-16-ethyl-4-hydroxy-5,9,13-trimethyl-2,10-dioxooxacyclohexadeca-11,13-diene-7-acetaldehyde; Fradizine; Tylocine; Tylosine. Grade: ≥99.0% by HPLC. CAS No. 8026-48-0. Molecular formula: C46H77NO17. Mole weight: 916.10.
Tylosin B
It is a 16-membered macrolide antibiotic and a metabolite of Tylosin. It is also a precursor of Tilmicosin. Synonyms: Desmycosin; 4A-O-De(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)tylosin; Demycarosyltylosin. Grade: ≥95.0% by HPLC. CAS No. 11032-98-7. Molecular formula: C39H65NO14. Mole weight: 771.93.
Tylosin monotartrate
Tylosin tartrate is a macrolide antibiotic produced by Streptomyces. Tylosin tartrate is an antimicrobial for gram-positive bacteria and mycoplasma. It can be used to prevent and treat respiratory diseases such as mycoplasma pneumonia, pleuropneumonia, swine pneumonia, Haemophilus parasuis, streptococcus suis, and other tissue infections. Synonyms: Tylosin, (2R,3R)-2,3-dihydroxybutanedioate (1:1); Tylosin, (2R,3R)-2,3-dihydroxybutanedioate (1:1) (salt); Tylosin, [R-(R*,R*)]-2,3-dihydroxybutanedioate (1:1) (salt); Pharmasin; Tylan Injectable; Tylan Soluble; Tylosin tartrate. Grade: >98%. CAS No. 74610-55-2. Molecular formula: C50H83NO23. Mole weight: 1066.19.
Tylvalosin
Tylvalosin, a macrolide antibiotic, is active against S. aureus, E. coli, and P. multocidas with MICs of 2, 128, and 128 μg/mL, respectively. Tylvalosin (5 and 10 μg/mL) reduces LPS-induced production of proinflammatory cytokines, prostaglandin E2 (PGE2) and nitric oxide in RAW 264.7 cells. Preparations containing tylvalosin have been used for the treatment and metaphylaxis of enzootic pneumonia caused by M. hyopneumoniae in pigs. Synonyms: 3-Acetate 4B-(3-methylbutanoate)-tylosin; 3-O-Acetyl-4''-O-isovaleryltylosin; Acetylisovaleryltylosin; 3-Acetyl-4''-isovaleryltylosin; AIV-tylosin; Tylosin acetate isovalerte; Oxacyclohexadeca-11,13-diene-7-acetaldehyde, 4-(acetyloxy)-15-[[(6-deoxy-2,3-di-O-methyl-β-D-allopyranosyl)oxy]methyl]-6-[[3,6-dideoxy-4-O-[2,6-dideoxy-3-C-methyl-4-O-(3-methyl-1-oxobutyl)-α-L-ribo-hexopyranosyl]-3-(dimethylamino)-β-D-glucopyranosyl]oxy]-16-ethyl-5,9,13-trimethyl-2,10-dioxo-, (4R,5S,6S,7R,9R,11E,13E,15R,16R)-. Grade: 90%. CAS No. 63409-12-1. Molecular formula: C53H87NO19. Mole weight: 1042.25.
Type A Allatostatin III
Type A Allatostatin III is a type A allatostatin. Synonyms: H-Gly-Gly-Ser-Leu-Tyr-Ser-Phe-Gly-Leu-NH2; Glycylglycyl-L-seryl-L-leucyl-L-tyrosyl-L-seryl-L-phenylalanylglycyl-L-leucinamide; Allatostatin 8 (Diploptera punctata); Allatostatin A 3 (Diploptera punctata); Allatostatin A 3; Allatostatin III (Diploptera punctata); AST 3; AST 8; Dippu-AST 8. Grade: 95%. CAS No. 123209-96-1. Molecular formula: C42H62N10O12. Mole weight: 899.01.
(Tyr0)-C-Peptide (dog)
(Tyr0)-C-Peptide (dog) is a biomedical product used to mimic the action of endogenous C-peptide hormone in dogs. It can potentially study diabetes mellitus type 1 in canines by regulating blood sugar levels and promoting insulin synthesis. Synonyms: Tyr-C-Peptide, dog; H-Tyr-Glu-Val-Glu-Asp-Leu-Gln-Val-Arg-Asp-Val-Glu-Leu-Ala-Gly-Ala-Pro-Gly-Glu-Gly-Gly-Leu-Gln-Pro-Leu-Ala-Leu-Glu-Gly-Ala-Leu-Gln-OH; L-tyrosyl-L-alpha-glutamyl-L-valyl-L-alpha-glutamyl-L-alpha-aspartyl-L-leucyl-L-glutaminyl-L-valyl-L-arginyl-L-alpha-aspartyl-L-valyl-L-alpha-glutamyl-L-leucyl-L-alanyl-glycyl-L-alanyl-L-prolyl-glycyl-L-alpha-glutamyl-glycyl-glycyl-L-leucyl-L-glutaminyl-L-prolyl-L-leucyl-L-alanyl-L-leucyl-L-alpha-glutamyl-glycyl-L-alanyl-L-leucyl-L-glutamine; L-Glutamine, L-tyrosyl-L-α-glutamyl-L-valyl-L-α-glutamyl-L-α-aspartyl-L-leucyl-L-glutaminyl-L-valyl-L-arginyl-L-α-aspartyl-L-valyl-L-α-glutamyl-L-leucyl-L-alanylglycyl-L-alanyl-L-prolylglycyl-L-α-glutamylglycylglycyl-L-leucyl-L-glutaminyl-L-prolyl-L-leucyl-L-alanyl-L-leucyl-L-α-glutamylglycyl-L-alanyl-L-leucyl-. Grade: 95%. CAS No. 101135-67-5. Molecular formula: C146H234N38O51. Mole weight: 3337.69.
(Tyr0)-C-Peptide (human)
(Tyr0)-C-Peptide (human) is a C-Peptide derivative used for radioimmunoassay. Synonyms: H-Tyr-Glu-Ala-Glu-Asp-Leu-Gln-Val-Gly-Gln-Val-Glu-Leu-Gly-Gly-Gly-Pro-Gly-Ala-Gly-Ser-Leu-Gln-Pro-Leu-Ala-Leu-Glu-Gly-Ser-Leu-Gln-OH; L-tyrosyl-L-alpha-glutamyl-L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-L-leucyl-L-glutaminyl-L-valyl-glycyl-L-glutaminyl-L-valyl-L-alpha-glutamyl-L-leucyl-glycyl-glycyl-glycyl-L-prolyl-glycyl-L-alanyl-glycyl-L-seryl-L-leucyl-L-glutaminyl-L-prolyl-L-leucyl-L-alanyl-L-leucyl-L-alpha-glutamyl-glycyl-L-seryl-L-leucyl-L-glutamine. Grade: ≥95% by HPLC. CAS No. 57327-90-9. Molecular formula: C138H220N36O50. Mole weight: 3183.43.
(Tyr27)-α-CGRP (27-37) (canine, mouse, rat)
(Tyr27)-α-CGRP (27-37) (canine, mouse, rat) is an empirically synthesized and selectively constructed peptide, epitomizing a conspicuous fragment of Calcitonin Gene-Related Peptide (CGRP). Synonyms: [Tyr0] Calcitonin Gene Related Peptide (28-37), rat; H-Tyr-Val-Pro-Thr-Asn-Val-Gly-Ser-Glu-Ala-Phe-NH2; L-tyrosyl-L-valyl-L-prolyl-L-threonyl-L-asparagyl-L-valyl-glycyl-L-seryl-L-alpha-glutamyl-L-alanyl-L-phenylalaninamide. Grade: 95%. CAS No. 124501-79-7. Molecular formula: C54H79N13O17. Mole weight: 1182.28.
(Tyr34)-pTH (7-34) amide (bovine)
(Tyr34)-pTH (7-34) amide (bovine) is an inhibitor of the action of parathyroid hormone in vivo. Synonyms: [Tyr34] Parathyroid Hormone (7-34), amide, bovine; H-Phe-Met-His-Asn-Leu-Gly-Lys-His-Leu-Ser-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Tyr-NH2; L-Phenylalanyl-L-methionyl-L-histidyl-L-asparaginyl-L-leucylglycyl-L-lysyl-L-histidyl-L-leucyl-L-seryl-L-seryl-L-methionyl-L-α-glutamyl-L-arginyl-L-valyl-L-α-glutamyl-3-(7H-indol-3-yl)-L-alanyl-L-leucyl-L-arginyl-L-lysyl-L-lysyl-L-leucyl-L-glutaminyl-L-α-aspartyl-L-valyl-L-histidyl-L-asparaginyl-L-tyrosinamide. Grade: ≥95% by HPLC. CAS No. 86292-93-5. Molecular formula: C156H244N48O40S2. Mole weight: 3496.03.
Tyr-(D-Dab4,Arg5,D-Trp8)-cyclo-Somatostatin-14 (4-11), a high affinity ligand of five somatostatin receptors (SST1-SST5), has higher binding affinity than omatostatin-14 and octreotide in AtT-20 mouse anterior pituitary tumor cells expressing SST2 and SST5 receptors. Synonyms: KE 108; H-Tyr-cyclo(-D-Dab-Arg-Phe-Phe-D-Trp-Lys-Thr-Phe); L-Tyrosyl-(2R)-2,4-diaminobutanoyl-L-arginyl-L-phenylalanyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-phenylalanine (9→2)-lactam; Benzenepropanamide, α-amino-N-[(3S,6S,9S,12R,15S,18S,21S,24R)-9-(4-aminobutyl)-21-[3-[(aminoiminomethyl)amino]propyl]-6-[(1R)-1-hydroxyethyl]-12-(1H-indol-3-ylmethyl)-2,5,8,11,14,17,20,23-octaoxo-3,15,18-tris(phenylmethyl)-1,4,7,10,13,16,19,22-octaazacyclohexacos-24-yl]-4-hydroxy-, (αS)-. Grade: 95%. CAS No. 496849-46-8. Molecular formula: C67H85N15O11. Mole weight: 1276.49.
Tyrocidine complex
It is a mixture of eight cationic cyclic decapeptides antibiotic produced by bacillus brevis. It has a broad spectrum of antimicrobial activity against gram-positive and Gram-negative bacteria. Tyrocidine A is the major component of the tyrothricin complex which is used for treatment of topical infection. It acts by disturbing lipid bilayers of the bacterial cell membrane. Grade: >95% by HPLC. CAS No. 8011-61-8. Molecular formula: C66H87N13O13 (for Tyrocidine A). Mole weight: 1270.48 (for Tyrocidine A).
Tyrosine Kinase Peptide 3
RR-src is a peptide tyrosine kinase substrate derived from the phosphorylation site of pp60(Src). It is used to monitor purification of insulin receptor and to determine tyrosine kinase activity. Synonyms: Arg-Arg-Leu-Ile-Glu-Asp-Ala-Glu-Tyr-Ala-Ala-Arg-Gly. CAS No. 81156-93-6. Molecular formula: C64H106N22O21. Mole weight: 1519.7.
Tyrothricin
Tyrothricin is a mixture of antibiotics isolated from Bacillus brevis. Synonyms: Bactralycin; Dermotricine; Hydrotricine; Coltirot; Martricin. Grade: >95%. CAS No. 1404-88-2. Molecular formula: C65H85N11O13. Mole weight: 1228.4.
Tyr-Ser-Pro-Trp-Thr-Asn-Phe
Tyr-Ser-Pro-Trp-Thr-Asn-Phe is a fascinating peptide sequence, offering hope for the research of multifarious conditions, ranging from neurodegenerative disorders to the perplexing complexity of cancer and diabetes. Synonyms: H-Tyr-Ser-Pro-Trp-Thr-Asn-Phe-OH; L-Tyrosyl-L-seryl-L-prolyl-L-tryptophyl-L-threonyl-L-asparaginyl-L-phenylalanine; L-Phenylalanine, L-tyrosyl-L-seryl-L-prolyl-L-tryptophyl-L-threonyl-L-asparaginyl-; RIP1; RIPK1, GST tagged human. Grade: 95%. CAS No. 228544-21-6. Molecular formula: C45H55N9O12. Mole weight: 913.97.
UCN-01
KRX-0601, also known as UCN-01, is a synthetic derivative of staurosporine with antineoplastic activity. It inhibits many phosphokinases, including the serine/threonine kinase AKT, calcium-dependent protein kinase C, and cyclin-dependent kinases. This agent arrests tumor cells in the G1/S of the cell cycle and prevents nucleotide excision repair by inhibiting the G2 checkpoint kinase chk1, resulting apoptosis. Uses: Antineoplastic agents. Synonyms: Antibiotic UCN 01; UCN01; Staurosporine; 7-hydroxystaurosporine; KW-2401; KW 2401; KW2401; (3R,9S,10R,11R,13R)-2,3,10,11,12,13-Hexahydro-3-hydroxy-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one; (+)-UCN-01; KRX 0601; NSC 638850. Grade: >99% by HPLC. CAS No. 112953-11-4. Molecular formula: C28H26N4O4. Mole weight: 482.53.
UFP-101
UFP-101 is a potent, selective and competitive silent antagonist for the NOP opioid receptor, displaying > 3000-fold selectivity over δ, μ and κ opioid receptors. UFP-101 exhibits antinociceptive activity by opposing the action of nociceptin in vivo. Synonyms: UFP-101; UFP 101; UFP101. Grade: >98%. CAS No. 849024-68-6. Molecular formula: C82H138N32O21. Mole weight: 1908.19.
UFP 803
UFP 803 is a urotensin-II (UT) receptor ligand that acts as a silent antagonist in most in vitro assays and in vivo. UFP 803 competitively antagonizes U-II induced contractions in the rat aorta (pIC50 = 7.46) and prevents plasma extravasation elicited by U-II in mice in vivo. Synonyms: UFP 803; UFP-803; UFP803. Grade: >98%. CAS No. 879497-82-2. Molecular formula: C50H64N10O12S2. Mole weight: 1061.24.
UK-1
UK-1, a benzoxazol derivative, has been found to be a Streptomyces metabolite that could exhibit anticancer activity and topoisomerase II restraination activity. Synonyms: UK 1, UK-1, UK1; [2,4'-Bibenzoxazole]-4-carboxylicacid, 2'-(2-hydroxyphenyl)-, methyl ester; ACMC-20n661; CTK4C6968; ZINC598610. Grade: 98%. CAS No. 151271-53-3. Molecular formula: C22H14N2O5. Mole weight: 386.36.
[UL-13C6gal]Lactose Monohydrate
[UL-13C6gal]Lactose Monohydrate is the labelled analogue of D-Lactose Monohydrate, which is used in the synthesis of casing for various methods of oral drug delivery, including dissolving pellets, and long-lasting pellets. Synonyms: [1',2',3',4',5',6'-13C6]lactose monohydrate; 4-O-beta-D-[UL-13C6]galactopyranosyl-D-glucose; lactose-1',2',3',4',5',6'-13C6 monohydrate. Molecular formula: C6[13C]6H24O12. Mole weight: 366.27.
Urantide
Urantide is a selective and competitive urotensin-II (UT) receptor antagonist (pKB = 8.3) that blocks hU-II induced contractions in thoracic aorta ex vivo. Urantide has no effect on noradrenaline or endothelin 1-induced contraction or on acetylcholine-induced relaxation. Urantide also exhibits partial agonist activity in a calcium mobilization assay (in CHO cells expressing hUT receptors). Synonyms: L-Valine, L-α-aspartyl-3-mercapto-L-valyl-L-phenylalanyl-D-tryptophyl-L-ornithyl-L-tyrosyl-L-cysteinyl-, cyclic (2→7)-disulfide; H-Asp-Pen(1)-Phe-D-Trp-Orn-Tyr-Cys(1)-Val-OH; L-alpha-aspartyl-L-penicillamyl-L-phenylalanyl-D-tryptophyl-L-ornithyl-L-tyrosyl-L-cysteinyl-L-valine (2->7)-disulfide acetic acid; (S)-4-(((4R,7S,10S,13R,16S,19R)-13-((1H-indol-3-yl)methyl)-10-(3-aminopropyl)-16-benzyl-4-(((S)-1-carboxy-2-methylpropyl)carbamoyl)-7-(4-hydroxybenzyl)-20,20-dimethyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-19-yl)amino)-3-amino-4-oxobutanoic acid. Grade: ≥95%. CAS No. 669089-53-6. Molecular formula: C51H66N10O12S2. Mole weight: 1075.26.
Urantide acetate
Urantide acetate is a selective and competitive urotensin-II (UT) receptor antagonist (pKB = 8.3) that blocks hU-II-induced contractions in the thoracic aorta ex vivo. Urantide has no effect on noradrenaline or endothelin 1-induced contraction or on acetylcholine-induced relaxation. Urantide also exhibits partial agonist activity in a calcium mobilization assay (in CHO cells expressing hUT receptors). Synonyms: L-Valine, L-α-aspartyl-3-mercapto-L-valyl-L-phenylalanyl-D-tryptophyl-L-ornithyl-L-tyrosyl-L-cysteinyl-, cyclic (2→7)-disulfide, acetate salt (1:1); H-Asp-Pen(1)-Phe-D-Trp-Orn-Tyr-Cys(1)-Val-OH.CH3CO2H; L-alpha-aspartyl-L-penicillamyl-L-phenylalanyl-D-tryptophyl-L-ornithyl-L-tyrosyl-L-cysteinyl-L-valine (2->7)-disulfide acetic acid; (S)-4-(((4R,7S,10S,13R,16S,19R)-13-((1H-indol-3-yl)methyl)-10-(3-aminopropyl)-16-benzyl-4-(((S)-1-carboxy-2-methylpropyl)carbamoyl)-7-(4-hydroxybenzyl)-20,20-dimethyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-19-yl)amino)-3-amino-4-oxobutanoic acid compound with acetic acid (1:1). Grade: ≥95%. Molecular formula: C53H70N10O14S2. Mole weight: 1135.32.
Urdamycin A
It is produced by the strain of Str. Violaceolatus, Kerriamycin B has anti-gram-positive bacterial effect and can also prolong the survival time of patients with Ai's ascites cancer. Synonyms: Kerriamycin B; (1R)-1,5-anhydro-2,6-dideoxy-3-O-{(2S,5S,6S)-5-[(2,6-dideoxy-beta-D-arabino-hexopyranosyl)oxy]-6-methyltetrahydro-2H-pyran-2-yl}-1-[(3R,4aR,12bS)-3,4a,8-trihydroxy-12b-{[(2S,5S,6S)-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-3-methyl-1,7,12-trioxo-1,2,3,4,4a,7,12,12b-octahydrobenzo[a]anthracen-9-yl]-D-arabino-hexitol. Grade: >97%. CAS No. 98474-21-6. Molecular formula: C43H56O17. Mole weight: 844.91.
Urea, polymer withformaldehyde, methylated
Urea, polymer withformaldehyde, methylated. CAS No. 68071-45-4. Molecular formula: C H4 N2 O. Mole weight: 90.0812.
Urechistachykinin II
Urechistachykinin II (Uru-TK II)is an invertebrate tachykinin-related peptides (TRPs) isolated from echiuroid worms, showing antimicrobial activities without a hemolytic effect. Synonyms: Uru-TK II; H-Ala-ala-gly-met-gly-phe-phe-gly-ala-arg-NH2. Grade: 95%. CAS No. 149097-04-1. Molecular formula: C44H66N14O10S. Mole weight: 983.15.
Uridine-5'-diphosphate trisodium salt
Uridine-5'-diphosphate trisodium salt is an indispensable biochemical compound utilized extensively in the nucleic acid synthesis and glycogen metabolism research. Within the tapestry of scientific exploration, Uridine-5'-diphosphate trisodium salt emerges as a pivotal player, intimately intertwined with the intricate fabric of RNA metabolism assessment, viral replication elucidation and the research of afflictions such as cancer and neurological disorders. Synonyms: 5'-UDP.Na3; Uridine 5'-(trihydrogendiphosphate), trisodium salt; ((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl diphosphate trisodium salt; trisodium uridine 5'-diphosphate; Uridine, 5'-(trihydrogen diphosphate), sodium salt (1:3); Trisodium UDP; UDP trisodium salt. Grade: ≥98% by HPLC. CAS No. 19817-91-5. Molecular formula: C9H11N2Na3O12P2. Mole weight: 470.11.
Uridine 5'-triphosphate dihydrate trisodium salt
Uridine 5'-triphosphate dihydrate trisodium salt, an indispensable compound extensively employed in the biomedical sector, serves diverse purposes. Primarily, it assumes a pivotal function in the intricate amalgamation of RNA and DNA, unequivocally contributing to cellular functioning. Synonyms: Uridine 5'-(tetrahydrogen triphosphate), sodium salt, hydrate (1:3:2); Uridine 5'-(tetrahydrogen triphosphate), trisodium salt, dihydrate; Uridine 5'-(tetrahydrogen triphosphate) trisodium salt, dihydrate; 5'-UTP trisodium salt, dihydrate; UTP trisodium salt, dihydrate. Grade: ≥90% by HPLC. CAS No. 116295-90-0. Molecular formula: C9H12N2Na3O15P3.2H2O. Mole weight: 586.12.
Uridine 5'-triphosphate trisodium salt
Uridine 5'-Triphosphate Trisodium Salt Hydrate is a polyphosphate analogue of uridine that is used in the synthesis of agonists at the G-protein-coupled P2Y receptors. Synonyms: UTP-Na3; Uridine 5'-triphosphoric acid trisodium salt; Uridine 5'-triphosphate trisodium; UTP Trisodium Salt; trisodium uridine triphospahte; trisodium uridine 5'-triphosphate; 5'-UTP 3Na; Uridine 5'-(tetrahydrogen triphosphate), trisodium salt. Grade: ≥95%. CAS No. 19817-92-6. Molecular formula: C9H12N2Na3O15P3. Mole weight: 550.09.
Uridine 5'-Triphosphate Trisodium Salt Hydrate
It is a polyphosphate analogue of the nucleoside uridine, which can be used in the preparation of potent and selective agonists at the G-protein-coupled P2Y receptors. Synonyms: Uridine 5'-(Tetrahydrogen Triphosphate) Trisodium Salt Hydrate; NSC 20260 Hydrate; Trisodium UTP Hydrate; UTP Trisodium Salt Hydrate; Utipina Hydrate. Grade: 95%. Molecular formula: C9H12N2Na3O15P3 xH2O. Mole weight: 550.09.
Uridine 5'-triphosphate trisodium salt monohydrate
UTP serves as a building block for RNA synthesis and modification, playing a vital role in cellular processes such as gene expression and protein synthesis. It is often utilized in research involving RNA labeling, transcription and RNA structural studies. Synonyms: Uridine 5'-(tetrahydrogen triphosphate), sodium salt, hydrate (1:3:1); Uridine 5'-triphosphate trisodium salt hydrate; UTP sodium salt hydrate; Uridine 5'-triphosphate, sodium salt hydrate. Grade: ≥90% by HPLC. CAS No. 1266569-92-9. Molecular formula: C9H14N2Na3O16P3. Mole weight: 568.10.
Urocanic acid
It is produced by the strain of Bac. subtilis var. theronophilus. Urocanic acid has an inhibitory effect on Eichner's ascites pain in animals. Synonyms: 4-imidazoleacrylic acid; trans-Urocanic acid; 5-Imidazoleacrylic acid; (2E)-3-(1H-IMIDAZOL-4-YL)ACRYLIC ACID; 3-(1H-Imidazol-4-yl)-2-propenoic acid; NSC 66357. Grade: 99%. CAS No. 104-98-3. Molecular formula: C6H6N2O2. Mole weight: 138.12.
Urocortin (human)
Urocortin (human) is a neuropeptide hormone that acts as an endogenous CRF agonist (Ki = 0.4, 0.3 and 0.5 nM for hCRF1, rCRF2α and mCRF2β, respectively). Synonyms: Human urocortin; Human urocortin 1; Human urocortin I. CAS No. 176591-49-4. Molecular formula: C204H337N63O64. Mole weight: 4696.29.
Urocortin II (human) trifluoroacetate salt
Urocortin II is a neuropeptide hormone that is a member of the corticotropin-releasing factor (CRF) family. Urocortin II is a highly selective agonist of the CRF2 receptor and does not show affinity for the CRF binding protein. Synonyms: PD080645. Grade: ≥95%. CAS No. 398001-88-2. Molecular formula: C196H340F3N63O56S. Mole weight: 4564.23.
Urocortin II (mouse)
Urocortin II (mouse) shows considerably high affinity for two splice variants of type 2 CRF receptor (CRF-R2) compared to CRF-R1. It activates CRF-R2α and CRF-R2β with almost the same potency as urocortin (rat). Synonyms: Ucn II (mouse); H-Val-Ile-Leu-Ser-Leu-Asp-Val-Pro-Ile-Gly-Leu-Leu-Arg-Ile-Leu-Leu-Glu-Gln-Ala-Arg-Tyr-Lys-Ala-Ala-Arg-Asn-Gln-Ala-Ala-Thr-Asn-Ala-Gln-Ile-Leu-Ala-His-Val-NH2. Grade: ≥95%. CAS No. 330648-32-3. Molecular formula: C187H320N56O50. Mole weight: 4152.95.
Urocortin (rat)
Urocortin (rat) is a neuropeptide hormone that acts as an endogenous CRF agonist (Ki = 13, 1.5 and 0.97 nM for hCRF1, rCRF2α and mCRF2β, respectively). Synonyms: Urocortin (Rattus norvegicus); Rat urocortin. CAS No. 171543-83-2. Molecular formula: C206H338N62O64. Mole weight: 4707.31.
Uroguanylin
Uroguanylin belongs to the guanylin family of cyclic guanosine monophosphate (cGMP) regulatory peptides. Uroguanylin activates the guanylate cyclase-C/cyclic guanosine monophosphate pathway to induce analgesic effects in colonic hypersensitive animal models, revealing a new approach for the treatment of abdominal pain. Synonyms: Uroguanylin Topoisomer A (human); UGN Topoisomer A (human); H-Asn-Asp-Asp-Cys-Glu-Leu-Cys-Val-Asn-Val-Ala-Cys-Thr-Gly-Cys-Leu-OH (Disulfide bridge: Cys4-Cys12, Cys7-Cys15); UGN (human); L-asparagyl-L-alpha-aspartyl-L-alpha-aspartyl-L-cysteinyl-L-alpha-glutamyl-L-leucyl-L-cysteinyl-L-valyl-L-asparagyl-L-valyl-L-alanyl-L-cysteinyl-L-threonyl-glycyl-L-cysteinyl-L-leucine (4->12),(7->15)-bis(disulfide); L-Asparaginyl-L-α-aspartyl-N-{(1R,4S,7S,10S,13S,16R,19S,22S,25R,32S,38R)-10-(2-amino-2-oxoethyl)-22-(2-carboxyethyl)-38-{[(1S)-1-carboxy-3-methylbutyl]carbamoyl}-32-[(1R)-1-hydroxyethyl]-19-isobutyl-7,13-diisopropyl-4-methyl-3,6,9,12,15,18,21,24,30,33,36-undecaoxo-27,28,40,41-tetrathia-2,5,8,11,14,17,20,23,31,34,37-undecaazabicyclo[14.13.13]dotetracont-25-yl}-L-α-asparagine. Grade: ≥90% by HPLC. CAS No. 154525-25-4. Molecular formula: C64H102N18O26S4. Mole weight: 1667.86.
Urotensin I
Urotensin I is, 41-aa neuropeptide, acts as an agonist of CRF receptor with pEC50s of 11.46, 9.36 and 9.85 for human CRF1, human CRF2 and rat CRF2α receptors in CHO cells, and Kis of 0.4, 1.8, and 5.7 nM for hCRF1, rCRF2α and mCRF2β receptors, respectively. Synonyms: Catostomus urotensin I. CAS No. 83930-33-0. Molecular formula: C210H340N62O67S2. Mole weight: 4869.45.
Urotensin II (114-124), human
Urotensin II (human) is an endogenous peptide agonist for the urotensin-II receptor (EC50 = 0.1 nM). Urotensin II (human) increases calcium levels in a concentration-dependent manner in HEK293 cells expressing human UTR (EC50 = 0.6 nM), and causes arterio-selective vasoconstriction and vasodilatation in mammals in vitro and in vivo. CAS No. 251293-28-4. Molecular formula: C64H85N13O18S2. Mole weight: 1388.57.
Urotensin II (114-124), human acetate
Urotensin II (human) is an endogenous peptide agonist for the urotensin-II receptor (EC50 = 0.1 nM). Urotensin II (human) increases calcium levels in a concentration-dependent manner in HEK293 cells expressing human UTR (EC50 = 0.6 nM), and causes arterio-selective vasoconstriction and vasodilatation in mammals in vitro and in vivo. Synonyms: L-Valine, L-α-glutamyl-L-threonyl-L-prolyl-L-α-aspartyl-L-cysteinyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-tyrosyl-L-cysteinyl-, cyclic (5→10)-disulfide acetate; Human UII acetate; Human urotensin II acetate; Urotensin II (human) acetate; H-Glu-Thr-Pro-Asp-Cys-Phe-Trp-Lys-Tyr-Cys-Val-OH.CH3CO2H (Disulfide bridge: Cys5-Cys10); L-alpha-glutamyl-L-threonyl-L-prolyl-L-alpha-aspartyl-L-cysteinyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-tyrosyl-L-cysteinyl-L-valine (5->10)-disulfide acetic acid. Grade: ≥95%. Molecular formula: C66H89N13O20S2. Mole weight: 1448.63.
Urotensin II (Gillichthys mirabilis) acetate
Urotensin II (Gillichthys mirabilis) acetate is a peptide ligand that is the strongest known vasoconstrictor. Synonyms: Urotensin II, mouse acetate; Gillichthys mirabilis urotensin II acetate; Urotensin II (Gillichthys mirabilis reduced), cyclic (6→11)-disulfide acetate; Urotensin II (goby) acetate; L-Valine, L-alanylglycyl-L-threonyl-L-alanyl-L-α-aspartyl-L-cysteinyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-tyrosyl-L-cysteinyl-, cyclic (6→11)-disulfide acetate; H-Ala-Gly-Thr-Ala-Asp-Cys-Phe-Trp-Lys-Tyr-Cys-Val-OH.CH3CO2H (Disulfide bridge: Cys6-Cys11); L-alanyl-glycyl-L-threonyl-L-alanyl-L-alpha-aspartyl-L-cysteinyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-tyrosyl-L-cysteinyl-L-valine (6->11)-disulfide acetate. Grade: ≥95%. Molecular formula: C64H88N14O19S2. Mole weight: 1421.61.
Urotensin II, mouse
Urotensin II, mouse, a potent vasoconstrictor, is an endogenous ligand for the orphan GPR14 or SENR. Synonyms: L-Isoleucine, 5-oxo-L-prolyl-L-histidylglycyl-L-alanyl-L-alanyl-L-prolyl-L-α-glutamyl-L-cysteinyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-tyrosyl-L-cysteinyl-, cyclic (8→13)-disulfide; H-Pyr-His-Gly-Ala-Ala-Pro-Glu-Cys-Phe-Trp-Lys-Tyr-Cys-Ile-OH (Disulfide bridge: Cys8-Cys13); L-pyroglutamyl-L-histidyl-glycyl-L-alanyl-L-alanyl-L-prolyl-L-alpha-glutamyl-L-cysteinyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-tyrosyl-L-cysteinyl-L-isoleucine (8->13)-disulfide; Urotensin II (mouse). Grade: ≥95%. CAS No. 405137-01-1. Molecular formula: C76H100N18O19S2. Mole weight: 1633.85.
Urotensin II, mouse acetate
Urotensin II, mouse acetate, a potent vasoconstrictor, is an endogenous ligand for the orphan GPR14 or SENR. Synonyms: L-Isoleucine, 5-oxo-L-prolyl-L-histidylglycyl-L-alanyl-L-alanyl-L-prolyl-L-α-glutamyl-L-cysteinyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-tyrosyl-L-cysteinyl-, cyclic (8→13)-disulfide, acetate; H-Pyr-His-Gly-Ala-Ala-Pro-Glu-Cys-Phe-Trp-Lys-Tyr-Cys-Ile-OH.CH3CO2H (Disulfide bridge: Cys8-Cys13); L-pyroglutamyl-L-histidyl-glycyl-L-alanyl-L-alanyl-L-prolyl-L-alpha-glutamyl-L-cysteinyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-tyrosyl-L-cysteinyl-L-isoleucine (8->13)-disulfide acetate; Urotensin II (mouse) acetate. Grade: ≥95%. Molecular formula: C78H104N18O21S2. Mole weight: 1693.92.
Urotensin II-Related Peptide (human, mouse, rat)
Urotensin II-Related Peptide (human, mouse, rat) has a high affinity for urotensin II receptors in human and rat with Kds of 170 and 91 pM, respectively. In addition, it produced a long lasting hypotensive effect in anesthetized rats at 10 nmol/kg. Synonyms: Urotensin IIB (human, mouse, rat); H-Ala-Cys-Phe-Trp-Lys-Tyr-Cys-Val-OH (Disulfide bridge: Cys2-Cys7); L-alanyl-L-cysteinyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-tyrosyl-L-cysteinyl-L-valine (2->7)-disulfide; UIIB (human, mouse, rat); URP (human, mouse, rat); N-{[(4R,7S,10S,13S,16S,19R)-19-(L-Alanylamino)-10-(4-aminobutyl)-16-benzyl-7-(4-hydroxybenzyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-L-valine. Grade: ≥95%. CAS No. 342878-90-4. Molecular formula: C49H64N10O10S2. Mole weight: 1017.22.