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?-4,5-Glycuronidase from Flavobacterium heparinum
The ?-4,5-Glycuronidase acts on the non-sulphated, unsaturated termini of disaccharides, tetrasaccharides, etc., produced either directly by lyase action on a glycosaminoglycan or by the action of the 2-O-sulphatase on an unsaturated disaccharide, tetrasaccharide, etc. Group: Enzymes. Synonyms: ?-4,5-Glycuronidase; Glycuronidase. Enzyme Commission Number: EC 3.2.1-. β-Glucosidase. Storage: Store frozen at -20 or below upon receipt. Avoid repeated freezethawing. Form: The enzyme is stabilised with 0.2% BSA, 0.22 um sterile-filtered and dispensed into sterile vials. To preserve high activity, the enzyme solution is stored frozen at -60°C and is supplied world-wide as a frozen solution. Source: Flavobacterium heparinum (ATCC 13125). ?-4,5-Glycuronidase; Glycuronidase. Cat No: NATE-1942.
4-acetamidobutyrate deacetylase
Also acts on N-acetyl-β-alanine and 5-acetamidopentanoate. Group: Enzymes. Enzyme Commission Number: EC 3.5.1.63. CAS No. 102347-82-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4453; 4-acetamidobutyrate deacetylase; EC 3.5.1.63; 102347-82-0. Cat No: EXWM-4453.
4-acetamidobutyryl-CoA deacetylase
The enzyme also hydrolyses 4-aminobutanoyl-CoA to aminobutanoate and coenzyme A. Group: Enzymes. Synonyms: aminobutyryl-CoA thiolesterase; deacetylase-thiolesterase. Enzyme Commission Number: EC 3.5.1.51. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4440; 4-acetamidobutyryl-CoA deacetylase; EC 3.5.1.51; aminobutyryl-CoA thiolesterase; deacetylase-thiolesterase. Cat No: EXWM-4440.
4a-hydroxytetrahydrobiopterin dehydratase
Catalyses the dehydration of 4a-hydroxytetrahydrobiopterins. Group: Enzymes. Synonyms: 4α-hydroxy-tetrahydropterin dehydratase; pterin-4α-carbinolamine dehydratase; 4a-hydroxytetrahydrobiopterin hydro-lyase. Enzyme Commission Number: EC 4.2.1.96. CAS No. 87683-70-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5080; 4a-hydroxytetrahydrobiopterin dehydratase; EC 4.2.1.96; 87683-70-3; 4α-hydroxy-tetrahydropterin dehydratase; pterin-4α-carbinolamine dehydratase; 4a-hydroxytetrahydrobiopterin hydro-lyase. Cat No: EXWM-5080.
4-alpha-D-{(1->4)-alpha-D-glucano}trehalose trehalohydrolase (EC 3.2.1.141) is an enzyme with systematic name 4-alpha-D-((1->4)-alpha-D-glucano)trehalose glucanohydrolase (trehalose-producing). Group: Enzymes. Synonyms: malto-oligosyltrehalose trehalohydrolase. Enzyme Commission Number: EC 3.2.1.141. CAS No. 170780-50-4. Maltooligosyl trehalose trehalohydrolase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3824; 4-α-D-{(1?4)-α-D-glucano}trehalose trehalohydrolase; EC 3.2.1.141; 170780-50-4; malto-oligosyltrehalose trehalohydrolase. Cat No: EXWM-3824.
4-alpha-D-{(1->4)-alpha-D-glucano}trehalose trehalohydrolase (EC 3.2.1.141) is an enzyme with systematic name 4-alpha-D-((1->4)-alpha-D-glucano)trehalose glucanohydrolase (trehalose-producing).
4-α-glucanotransferase
This entry covers the former separate entry for EC 2.4.1.3 (amylomaltase). The plant enzyme has been termed D-enzyme. An enzymic activity of this nature forms part of the mammalian and yeast glycogen debranching system (see EC 3.2.1.33 amylo-α-1,6-glucosidase). Group: Enzymes. Synonyms: disproportionating enzyme; dextrin glycosyltransferase; D-enzyme; debranching enzyme maltodextrin glycosyltransferase; amylomaltase; dextrin transglycosylase; 1,4-α-D-glucan:1,4-α-D-glucan 4-α-D-glycosyltransferase. Enzyme Commission Number: EC 2.4.1.25. CAS No. 9032-9-1. Amylomaltase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2479; 4-α-glucanotransferase; EC 2.4.1.25; 9032-09-1; disproportionating enzyme; dextrin glycosyltransferase; D-enzyme; debranching enzyme maltodextrin glycosyltransferase; amylomaltase; dextrin transglycosylase; 1,4-α-D-glucan:1,4-α-D-glucan 4-α-D-glycosyltransferase. Cat No: EXWM-2479.
4-aminobenzoate 1-monooxygenase
A flavoprotein (FAD). Acts on anthranilate and 4-aminosalicylate but not on salicylate (cf. EC 1.14.13.1 salicylate 1-monooxygenase). Group: Enzymes. Synonyms: 4-aminobenzoate hydroxylase; 4-aminobenzoate monooxygenase. Enzyme Commission Number: EC 1.14.13.27. CAS No. 98668-55-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0834; 4-aminobenzoate 1-monooxygenase; EC 1.14.13.27; 98668-55-4; 4-aminobenzoate hydroxylase; 4-aminobenzoate monooxygenase. Cat No: EXWM-0834.
4-aminobutyrate-2-oxoglutarate transaminase
Requires pyridoxal phosphate. Some preparations also act on β-alanine, 5-aminopentanoate and (R,S)-3-amino-2-methylpropanoate. Group: Enzymes. Synonyms: β-alanine-oxoglutarate transaminase; aminobutyrate aminotransferase (ambiguous); β-alanine aminotransferase; β-alanine-oxoglutarate aminotransferase; γ-aminobutyrate aminotransaminase (ambiguous); γ-aminobutyrate transaminase (ambiguous); γ-aminobutyrate-α-ketoglutarate aminotransferase; γ-aminobutyrate-α-ketoglutarate transaminase; γ-aminobutyrate:α-oxoglutarate aminotransferase; γ-aminobutyric acid aminotransferase (ambiguous); γ-aminobutyric acid transaminase (ambiguous); γ-aminobutyric acid-α-ketoglutarate transaminase; γ-aminobutyric acid-α-ketoglutaric acid aminotransferase; γ-aminobutyric acid-2-oxoglutarate transaminase; γ-aminobutyric transaminase (ambiguous); 4-aminobutyrate aminotransferase (ambiguous); 4-aminobutyrate-2-ketoglutarate aminotransferase; 4-aminobutyrate-2-oxoglutarate aminotransferase. Enzyme Commission Number: EC 2.6.1.19. CAS No. 9037-67-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2859; 4-aminobutyrate-2-oxoglutarate transaminase; EC 2.6.1.19; 9037-67-.
4-aminobutyrate-pyruvate transaminase
Requires pyridoxal 5'-phosphate. The enzyme is found in plants that do not have the 2-oxoglutarate dependent enzyme (cf. EC 2.6.1.19). The reaction with pyruvate is reversible while the reaction with glyoxylate only takes place in the forward direction. Group: Enzymes. Synonyms: aminobutyrate aminotransferase (ambiguous); γ-aminobutyrate aminotransaminase (ambiguous); γ-aminobutyrate transaminase (ambiguous); γ-aminobutyric acid aminotransferase (ambiguous); γ-aminobutyric acid pyruvate transamin. Enzyme Commission Number: EC 2.6.1.96. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2937; 4-aminobutyrate-pyruvate transaminase; EC 2.6.1.96; aminobutyrate aminotransferase (ambiguous); γ-aminobutyrate aminotransaminase (ambiguous); γ-aminobutyrate transaminase (ambiguous); γ-aminobutyric acid aminotransferase (ambiguous); γ-aminobutyric acid pyruvate transaminase; γ-aminobutyric acid transaminase (ambiguous); γ-aminobutyric transaminase (ambiguous); 4-aminobutyrate aminotransferase (ambiguous); 4-aminobutyric acid aminotransferase (ambiguous); aminobutyrate transaminase (ambiguous); GABA aminotransferase (ambiguous); GABA transaminase (ambiguous); GABA transferase; POP2 (gene name). Cat No: EXWM-2937.
4-carboxymethyl-4-methylbutenolide mutase
This enzyme belongs to the family of isomerases, specifically those intramolecular transferases transferring other groups. Group: Enzymes. Synonyms: 4-methyl-2-enelactone isomerase; 4-methylmuconolactone methylisomerase; 4-methyl-3-enelactone methyl isomerase. Enzyme Commission Number: EC 5.4.99.14. CAS No. 115300-03-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5553; 4-carboxymethyl-4-methylbutenolide mutase; EC 5.4.99.14; 115300-03-3; 4-methyl-2-enelactone isomerase; 4-methylmuconolactone methylisomerase; 4-methyl-3-enelactone methyl isomerase. Cat No: EXWM-5553.
4-carboxymuconolactone decarboxylase
This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. This enzyme participates in benzoate degradation via hydroxylation. Group: Enzymes. Synonyms: γ-4-carboxymuconolactone decarboxylase; 4-carboxymuconolactone carboxy-lyase; 2-carboxy-2,5-dihydro-5-oxofuran-2-acetate carboxy-lyase (4,5-dihydro-5-oxofuran-2-acetate-forming). Enzyme Commission Number: EC 4.1.1.44. CAS No. 37289-46-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4789; 4-carboxymuconolactone decarboxylase; EC 4.1.1.44; 37289-46-6; γ-4-carboxymuconolactone decarboxylase; 4-carboxymuconolactone carboxy-lyase; 2-carboxy-2,5-dihydro-5-oxofuran-2-acetate carboxy-lyase (4,5-dihydro-5-oxofuran-2-acetate-forming). Cat No: EXWM-4789.
4-chlorobenzoate-CoA ligase
Requires Mg2+. This enzyme is part of the bacterial 2,4-dichlorobenzoate degradation pathway. Group: Enzymes. Enzyme Commission Number: EC 6.2.1.33. CAS No. 141583-20-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5691; 4-chlorobenzoate-CoA ligase; EC 6.2.1.33; 141583-20-2. Cat No: EXWM-5691.
4-chlorobenzoate dehalogenase
Catalyses the first step in the degradation of chlorobenzoate in Pseudomonas. In many microorganisms, this activity comprises three separate enzymes, EC 6.2.1.33 (4-chlorobenzoate-CoA ligase), EC 3.8.1.7 (4-chlorobenzoyl-CoA dehalogenase) and EC 3.1.2.23 (4-hydroxybenzoyl-CoA thioesterase). Group: Enzymes. Synonyms: halobenzoate dehalogenase. Enzyme Commission Number: EC 3.8.1.6. CAS No. 94047-11-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4745; 4-chlorobenzoate dehalogenase; EC 3.8.1.6; 94047-11-7; halobenzoate dehalogenase. Cat No: EXWM-4745.
4-chlorobenzoyl-CoA dehalogenase
Specific for dehalogenation at the 4-position. Can dehalogenate substrates bearing fluorine, chlorine, bromine and iodine in the 4-position. This enzyme is part of the bacterial 2,4-dichlorobenzoate degradation pathway. Group: Enzymes. Enzyme Commission Number: EC 3.8.1.7. CAS No. 141583-18-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4746; 4-chlorobenzoyl-CoA dehalogenase; EC 3.8.1.7; 141583-18-8. Cat No: EXWM-4746.
4-chlorophenylacetate 3,4-dioxygenase
A system, containing a reductase and an iron-sulfur oxygenase, and no independent ferredoxin. Requires Fe2+. Also acts on 4-bromophenyl acetate. Group: Enzymes. Enzyme Commission Number: EC 1.14.12.9. CAS No. 105006-00-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0697; 4-chlorophenylacetate 3,4-dioxygenase; EC 1.14.12.9; 105006-00-6. Cat No: EXWM-0697.
4-coumarate-CoA ligase
This enzyme belongs to the family of ligases, to be specific those forming carbon-sulfur bonds as acid-thiol ligases. This enzyme participates in phenylpropanoid biosynthesis. Group: Enzymes. Synonyms: 4-coumaroyl-CoA synthetase; p-coumaroyl CoA ligase; p-coumaryl coenzyme A synthetase; p-coumaryl-CoA synthetase; p-coumaryl-CoA ligase; feruloyl CoA ligase; hydroxycinnamoyl CoA synthetase; 4-coumarate:coenzyme A ligase; caffeolyl coenzyme A synthetase; p-hydroxycinnamoyl coenzyme A synthetase; feruloyl coenzyme A synthetase; sinapoyl coenzyme A synthetase; 4-coumaryl-CoA synthetase; hydroxycinnamate:CoA ligase; p-coumaryl-Co. Enzyme Commission Number: EC 6.2.1.12. CAS No. 37332-51-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5670; 4-coumarate-CoA ligase; EC 6.2.1.12; 37332-51-7; 4-coumaroyl-CoA synthetase; p-coumaroyl CoA ligase; p-coumaryl coenzyme A synthetase; p-coumaryl-CoA synthetase; p-coumaryl-CoA ligase; feruloyl CoA ligase; hydroxycinnamoyl CoA synthetase; 4-coumarate:coenzyme A ligase; caffeolyl coenzyme A synthetase; p-hydroxycinnamoyl coenzyme A synthetase; feruloyl coenzyme A synthetase; sinapoyl coenzyme A synthetase; 4-coumaryl-CoA synthetase; hydroxycinnamate:CoA ligase; p-coumaryl-CoA ligase; p-hydroxycinnamic acid:CoA ligase; 4CL. Cat No: EXWM-5670.
4-coumaroyl-homoserine lactone synthase
The enzyme is found in the bacterium Rhodopseudomonas palustris, which produces N-(4-coumaroyl)-L-homoserine lactone as a quorum-sensing signal. Group: Enzymes. Synonyms: p-coumaryl-homoserine lactone synthase; RpaI. Enzyme Commission Number: EC 2.3.1.229. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2176; 4-coumaroyl-homoserine lactone synthase; EC 2.3.1.229; p-coumaryl-homoserine lactone synthase; RpaI. Cat No: EXWM-2176.
The enzyme from Escherichia coli requires Mg2+ or Mn2+. Forms part of an alternative nonmevalonate pathway for terpenoid biosynthesis (for diagram, click here). Group: Enzymes. Synonyms: CDP-ME kinase. Enzyme Commission Number: EC 2.7.1.148. CAS No. 263016-77-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2978; 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; EC 2.7.1.148; 263016-77-9; CDP-ME kinase. Cat No: EXWM-2978.
This cytochrome P450 enzyme, characterized from the plant Sinopodophyllum hexandrum, produces the direct precursor to etoposide, a potent anticancer drug. It can also act on (-)-deoxypodophyllotoxin with lower efficiency. Group: Enzymes. Synonyms: CYP82D61 (gene name). Enzyme Commission Number: EC 1.14.13.214. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0816; (-)-4'-demethyl-deoxypodophyllotoxin 4-hydroxylase; EC 1.14.13.214; CYP82D61 (gene name). Cat No: EXWM-0816.
4'-demethylrebeccamycin synthase
This enzyme catalyses a step in the biosynthesis of rebeccamycin, an indolocarbazole alkaloid produced by the bacterium Lechevalieria aerocolonigenes. The enzyme is a glycosylase, and acts in the reverse direction to that shown. It has a wide substrate range, and was shown to glycosylate several substrates, including the staurosporine aglycone, EJG-III-108A, J-104303, 6-N-methyl-arcyriaflavin C and indolo-[2,3-a]-carbazole. Group: Enzymes. Synonyms: arcyriaflavin A N-glycosyltransferase; RebG. Enzyme Commission Number: EC 4.3.3.5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5306; 4'-demethylrebeccamycin synthase; EC 4.3.3.5; arcyriaflavin A N-glycosyltransferase; RebG. Cat No: EXWM-5306.
The enzyme catalyses a step in the pathway leading to biosynthesis of ergot alkaloids in certain fungi. Group: Enzymes. Synonyms: fgaMT (gene name); easF (gene name). Enzyme Commission Number: EC 2.1.1.261. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1866; 4-dimethylallyltryptophan N-methyltransferase; EC 2.1.1.261; fgaMT (gene name); easF (gene name). Cat No: EXWM-1866.
4-dimethylallyltryptophan synthase
This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. Group: Enzymes. Synonyms: dimethylallylpyrophosphate:L-tryptophan dimethylallyltransferase; dimethylallyltryptophan synthetase; dimethylallylpyrophosphate: tryptophan dimethylallyl transferase; DMAT synthetase; 4-(γ,γ-dimethylallyl)tryptophan synthase; tryptophan dimethylallyltransferase. Enzyme Commission Number: EC 2.5.1.34. CAS No. 55127-01-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2771; 4-dimethylallyltryptophan synthase; EC 2.5.1.34; 55127-01-0; dimethylallylpyrophosphate:L-tryptophan dimethylallyltransferase; dimethylallyltryptophan synthetase; dimethylallylpyrophosphate: tryptophan dimethylallyl transferase; DMAT synthetase; 4-(γ,γ-dimethylallyl)tryptophan synthase; tryptophan dimethylallyltransferase. Cat No: EXWM-2771.
4-(dimethylamino)phenylazoxybenzene reductase
This enzyme belongs to the family of oxidoreductases, specifically those acting on other nitrogenous compounds as donors with NAD+ or NADP+ as acceptor. Group: Enzymes. Synonyms: N,N-dimethyl-p-aminoazobenzene oxide reductase; dimethylaminoazobenzene N-oxide reductase; NADPH-dependent DMAB N-oxide reductase; NADPH:4-(dimethylamino)phenylazoxybenzene oxidoreductase. Enzyme Commission Number: EC 1.7.1.11. CAS No. 103843-39-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1604; 4-(dimethylamino)phenylazoxybenzene reductase; EC 1.7.1.11; 103843-39-6; N,N-dimethyl-p-aminoazobenzene oxide reductase; dimethylaminoazobenzene N-oxide reductase; NADPH-dependent DMAB N-oxide reductase; NADPH:4-(dimethylamino)phenylazoxybenzene oxidoreductase. Cat No: EXWM-1604.
Involved in the toluene-4-sulfonate degradation pathway. Group: Enzymes. Enzyme Commission Number: EC 1.2.1.62. CAS No. 167973-68-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1164; 4-formylbenzenesulfonate dehydrogenase; EC 1.2.1.62; 167973-68-4. Cat No: EXWM-1164.
Normally acts on a glycoconjugate where R (see reaction) is a glycoprotein or glycolipid. This enzyme fucosylates on O-3 of an N-acetylglucosamine that carries a galactosyl group on O-4, unlike EC 2.4.1.65, 3-galactosyl-N-acetylglucosaminide 4-α-L-fucosyltransferase, which fucosylates on O-4 of an N-acetylglucosamine that carries a galactosyl group on O-3. Group: Enzymes. Synonyms: Lewis-negative α-3-fucosyltransferase; plasma α-3-fucosyltransferase; guanosine diphosphofucose-glucoside α1?3-fucosyltransferase; galactoside 3-fu. Enzyme Commission Number: EC 2.4.1.152. CAS No. 39279-34-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2378; 4-galactosyl-N-acetylglucosaminide 3-α-L-fucosyltransferase; EC 2.4.1.152; 39279-34-0; Lewis-negative α-3-fucosyltransferase; plasma α-3-fucosyltransferase; guanosine diphosphofucose-glucoside α1?3-fucosyltransferase; galactoside 3-fucosyltransferase; GDP-L-fucose:1,4-β-D-galactosyl-N-acetyl-D-glucosaminyl-R 3-L-fucosyltransferase; GDP-β-L-fucose:1,4-β-D-galactosyl-N-acetyl-D-glucosaminyl-R 3-L-fucosyltransferase; GDP-β-L-fucose:1,4-β-D-galactosyl-N-acetyl-D-glucosaminyl-R 3-α-L-fucosyltransferase. Cat No: EXWM-2378.
Catalyses a step in the biosynthesis of the side chain of the aminoglycoside antibiotics of the butirosin family. FMNH2 is used as a free cofactor. Forms a complex with a dedicated NAD(P)H:FMN oxidoreductase. The enzyme is not able to hydroxylate free substrates, activation by the acyl-carrier protein is mandatory.Octanoyl-S-[BtrI acyl-carrier protein] is also accepted. Group: Enzymes. Synonyms: btrO (gene name). Enzyme Commission Number: EC 1.14.14.13. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0910; 4-(γ-L-glutamylamino)butanoyl-[BtrI acyl-carrier protein] monooxygenase; EC 1.14.14.13; btrO (gene name). Cat No: EXWM-0910.
4-hydroxy-2-oxoglutarate aldolase
The enzymes from rat liver and bovine liver act on both enantiomers of 4-hydroxy-2-oxoglutarate. cf. EC 4.1.3.42, L-4-hydroxy-2-oxoglutarate aldolase. Group: Enzymes. Synonyms: 2-oxo-4-hydroxyglutarate aldolase; hydroxyketoglutaric aldolase; 4-hydroxy-2-ketoglutaric aldolase; 2-keto-4-hydroxyglutaric aldolase; 4-hydroxy-2-ketoglutarate aldolase; 2-keto-4-hydroxyglutarate aldolase; 2-oxo-4-hydroxyglutaric aldolase; DL-4-hydroxy-2-ketoglutarate aldolase; hydroxyketoglutarate aldolase; 2-keto-4-hydroxybutyrate aldolase; 4-hydroxy-2-oxoglutarate glyoxylate-lyase; KHGA. Enzyme Commission Number: EC 4.1.3.16. CAS No. 9030-81-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4901; 4-hydroxy-2-oxoglutarate aldolase; EC 4.1.3.16; 9030-81-3; 2-oxo-4-hydroxyglutarate aldolase; hydroxyketoglutaric aldolase; 4-hydroxy-2-ketoglutaric aldolase; 2-keto-4-hydroxyglutaric aldolase; 4-hydroxy-2-ketoglutarate aldolase; 2-keto-4-hydroxyglutarate aldolase; 2-oxo-4-hydroxyglutaric aldolase; DL-4-hydroxy-2-ketoglutarate aldolase; hydroxyketoglutarate aldolase; 2-keto-4-hydroxybutyrate aldolase; 4-hydroxy-2-oxoglutarate glyoxylate-lyase; KHGA. Cat No: EXWM-4901.
4-hydroxy-2-oxoheptanedioate aldolase
Requires Co2+ or Mn2+ for activity. The enzyme is also able to catalyse the aldol cleavage of 4-hydroxy-2-oxopentanoate and 4-hydroxy-2-oxohexanoate, and can use 2-oxobutanoate as carbonyl donor, with lower efficiency. In the reverse direction, is able to condense a range of aldehyde acceptors with pyruvate. The enzyme from the bacterium Escherichia coli produces a racemic mixture of (4R)- and (4S)-hydroxy-2-oxoheptanedioate. Group: Enzymes. Synonyms: 2,4-dihydroxyhept-2-enedioate aldolase; HHED aldolase; 4-hydroxy-2-ketoheptanedioate aldolase; HKHD aldolase; HpcH; HpaI; 4-hydroxy-2-oxoheptanedioate succinate semialdehyde lyase (pyruvate-forming). Enzyme Commission Number: EC 4.1.2.52. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4889; 4-hydroxy-2-oxoheptanedioate aldolase; EC 4.1.2.52; 2,4-dihydroxyhept-2-enedioate aldolase; HHED aldolase; 4-hydroxy-2-ketoheptanedioate aldolase; HKHD aldolase; HpcH; HpaI; 4-hydroxy-2-oxoheptanedioate succinate semialdehyde lyase (pyruvate-forming). Cat No: EXWM-4889.
4-hydroxy-2-oxohexanoate aldolase
Requires Mn2+ for maximal activity. The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 4.1.3.39, 4-hydroxy-2-oxovalerate aldolase. The enzyme forms a bifunctional complex with EC 1.2.1.87, propanal dehydrogenase (CoA-propanoylating), with a tight channel connecting the two subunits. Group: Enzymes. Synonyms: BphI. Enzyme Commission Number: EC 4.1.3.43. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4920; 4-hydroxy-2-oxohexanoate aldolase; EC 4.1.3.43; BphI. Cat No: EXWM-4920.
4-hydroxy-2-oxovalerate aldolase
Requires Mn2+ for maximal activity. The enzyme from the bacterium Pseudomonas putida is also stimulated by NADH. In some bacterial species the enzyme forms a bifunctional complex with EC 1.2.1.10, acetaldehyde dehydrogenase (acetylating). The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 4.1.3.43, 4-hydroxy-2-oxohexanoate aldolase. Group: Enzymes. Synonyms: 4-hydroxy-2-ketovalerate aldolase; HOA; DmpG; 4-hydroxy-2-oxovalerate pyruvate-lyase; 4-hydroxy-2-oxopentanoate pyruvate-lyase; BphI; 4-hydroxy-2-oxopentanoate pyruvate-lyase (acetaldehyde-forming). Enzyme Commission Number: EC 4.1.3.39. CAS No. 37325-52-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4915; 4-hydroxy-2-oxovalerate aldolase; EC 4.1.3.39; 37325-52-3; 4-hydroxy-2-ketovalerate aldolase; HOA; DmpG; 4-hydroxy-2-oxovalerate pyruvate-lyase; 4-hydroxy-2-oxopentanoate pyruvate-lyase; BphI; 4-hydroxy-2-oxopentanoate pyruvate-lyase (acetaldehyde-forming). Cat No: EXWM-4915.
An iron-sulfur protein that contains either a [3Fe-4S] or a [4Fe-4S] cluster. This enzyme forms a system with a ferredoxin or a flavodoxin and an NAD(P)H-dependent reductase. This is the last enzyme in the non-mevalonate pathway for isoprenoid biosynthesis. This pathway, also known as the 1-deoxy-D-xylulose 5-phosphate (DOXP) or as the 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway, is found in most bacteria and in plant chloroplasts. The enzyme acts in the reverse direction, producing a 5:1 mixture of isopentenyl diphosphate and dimethylallyl diphosphate. Group: Enzymes. Synonyms: isopentenyl-diphosphate:NADP+ oxidoreductase; LytB; (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase; HMBPP reductase; IspH; LytB/IspH. Enzyme Commission Number: EC 1.17.7.4. CAS No. 512789-14-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1099; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase; EC 1.17.7.4; 512789-14-9; isopentenyl-diphosphate:NADP+ oxidoreductase; LytB; (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase; HMBPP reductase; IspH; LytB/IspH. Cat No: EXWM-1099.
4-hydroxy-3-polyprenylbenzoate decarboxylase
The enzyme catalyses a step in prokaryotic ubiquinone biosynthesis, as well as in plastoquinone biosynthesis in cyanobacteria. The enzyme can accept substrates with different polyprenyl tail lengths in vitro, but uses a specific length in vivo, which is determined by the polyprenyl diphosphate synthase that exists in the specific organism. It requires a prenylated flavin cofactor that is produced by EC 2.5.1.129, flavin prenyltransferase. Group: Enzymes. Synonyms: ubiD (gene name); 4-hydroxy-3-solanesylbenzoate decarboxylase; 3-octaprenyl-4-hydroxybenzoate decarboxylase. Enzyme Commission Number: EC 4.1.1.98. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4848; 4-hydroxy-3-polyprenylbenzoate decarboxylase; EC 4.1.1.98; ubiD (gene name); 4-hydroxy-3-solanesylbenzoate decarboxylase; 3-octaprenyl-4-hydroxybenzoate decarboxylase. Cat No: EXWM-4848.
4-hydroxy-4-methyl-2-oxoglutarate aldolase
Requires a divalent metal ion. This enzyme participates in the degradation of protocatechuate (via the meta-cleavage pathway), phthalate, syringate and gallate. The enzyme from Pseudomonas ochraceae can also cleave 4-hydroxy-2-oxoglutarate to glyoxylate and pyruvate, and also catalyses the reaction of EC 4.1.1.3 (oxaloacetate decarboxylase). Group: Enzymes. Synonyms: pyruvate aldolase; γ-methyl-γ-hydroxy-α-ketoglutaric aldolase; 4-hydroxy-4-methyl-2-ketoglutarate aldolase; 4-hydroxy-4-methyl-2-oxoglutarate pyruvate-lyase; HMG aldolase; CHA aldolase; 4-carboxy-4-hydroxy-2-oxoadipate aldolase. Enzyme Commission Number: EC 4.1.3.17. CAS No. 37290-65-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4902; 4-hydroxy-4-methyl-2-oxoglutarate aldolase; EC 4.1.3.17; 37290-65-6; pyruvate aldolase; γ-methyl-γ-hydroxy-α-ketoglutaric aldolase; 4-hydroxy-4-methyl-2-ketoglutarate aldolase; 4-hydroxy-4-methyl-2-oxoglutarate pyruvate-lyase; HMG aldolase; CHA aldolase; 4-carboxy-4-hydroxy-2-oxoadipate aldolase. Cat No: EXWM-4902.
The enzyme from Triticum aestivum (wheat) has a higher affinity for DIMBOA glucoside than DIBOA glucoside. With Secale cereale (rye) the preference is reversed. Group: Enzymes. Synonyms: DIMBOAGlc hydrolase; DIMBOA glucosidase. Enzyme Commission Number: EC 3.2.1.182. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3866; 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside β-D-glucosidase; EC 3.2.1.182; DIMBOAGlc hydrolase; DIMBOA glucosidase. Cat No: EXWM-3866.
The enzyme from Triticum aestivum (wheat) has a higher affinity for DIMBOA glucoside than DIBOA glucoside. With Secale cereale (rye) the preference is reversed.
4-hydroxyacetophenone monooxygenase
Contains FAD. The enzyme from Pseudomonas fluorescens ACB catalyses the conversion of a wide range of acetophenone derivatives. Highest activity occurs with compounds bearing an electron-donating substituent at the para position of the aromatic ring. In the absence of substrate, the enzyme can act as an NAD(P)H oxidase (EC 1.6.3.1). Group: Enzymes. Synonyms: HAPMO. Enzyme Commission Number: EC 1.14.13.84. CAS No. 156621-13-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0892; 4-hydroxyacetophenone monooxygenase; EC 1.14.13.84; 156621-13-5; HAPMO. Cat No: EXWM-0892.
4-hydroxybenzaldehyde dehydrogenase (NAD+)
The bacterial enzyme (characterized from an unidentified denitrifying bacterium) is involved in an anaerobic toluene degradation pathway. The plant enzyme is involved in formation of 4-hydroxybenzoate, a cell wall-bound phenolic acid that plays a major role in plant defense against pathogens. cf. EC 1.2.1.96, 4-hydroxybenzaldehyde dehydrogenase (NADP+). Group: Enzymes. Synonyms: p-hydroxybenzaldehyde dehydrogenase (ambiguous); 4-hydroxybenzaldehyde dehydrogenase (ambiguous). Enzyme Commission Number: EC 1.2.1.64. CAS No. 61229-72-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1166; 4-hydroxybenzaldehyde dehydrogenase (NAD+); EC 1.2.1.64; 61229-72-9; p-hydroxybenzaldehyde dehydrogenase (ambiguous); 4-hydroxybenzaldehyde dehydrogenase (ambiguous). Cat No: EXWM-1166.
4-hydroxybenzaldehyde dehydrogenase (NADP+)
Involved in the aerobic pathway for degradation of toluene, 4-methylphenol, and 2,4-xylenol by several Pseudomonas strains. The enzyme is also active with 4-hydroxy-3-methylbenzaldehyde. cf. EC 1.2.1.64, 4-hydroxybenzaldehyde dehydrogenase (NAD+). Group: Enzymes. Synonyms: p-hydroxybenzaldehyde dehydrogenase (ambiguous); pchA (gene name). Enzyme Commission Number: EC 1.2.1.96. CAS No. 61229-72-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1200; 4-hydroxybenzaldehyde dehydrogenase (NADP+); EC 1.2.1.96; 61229-72-9; p-hydroxybenzaldehyde dehydrogenase (ambiguous); pchA (gene name). Cat No: EXWM-1200.
4-hydroxybenzoate 1-hydroxylase
Requires FAD. The enzyme from Candida parapsilosis is specific for 4-hydroxybenzoate derivatives and prefers NADH to NADPH as electron donor. Group: Enzymes. Synonyms: 4-hydroxybenzoate 1-monooxygenase. Enzyme Commission Number: EC 1.14.13.64. CAS No. 134214-78-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0871; 4-hydroxybenzoate 1-hydroxylase; EC 1.14.13.64; 134214-78-1; 4-hydroxybenzoate 1-monooxygenase. Cat No: EXWM-0871.
4-hydroxybenzoate 3-monooxygenase
A flavoprotein (FAD). Most enzymes from Pseudomonas are highly specific for NADPH (cf. EC 1.14.13.33 4-hydroxybenzoate 3-monooxygenase [NAD(P)H]). Group: Enzymes. Synonyms: p-hydroxybenzoate hydrolyase; p-hydroxybenzoate hydroxylase; 4-hydroxybenzoate 3-hydroxylase; 4-hydroxybenzoate monooxygenase; 4-hydroxybenzoic hydroxylase; p-hydroxybenzoate-3-hydroxylase; p-hydroxybenzoic acid hydrolase; p-hydroxybenzoic acid hydroxylase; p-hydroxybenzoic hydroxylase. Enzyme Commission Number: EC 1.14.13.2. CAS No. 9059-23-8. p-Hydroxybenzoate Hydroxylase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0800; 4-hydroxybenzoate 3-monooxygenase; EC 1.14.13.2; 9059-23-8; p-hydroxybenzoate hydrolyase; p-hydroxybenzoate hydroxylase; 4-hydroxybenzoate 3-hydroxylase; 4-hydroxybenzoate monooxygenase; 4-hydroxybenzoic hydroxylase; p-hydroxybenzoate-3-hydroxylase; p-hydroxybenzoic acid hydrolase; p-hydroxybenzoic acid hydroxylase; p-hydroxybenzoic hydroxylase. Cat No: EXWM-0800.
4-hydroxybenzoate 3-monooxygenase [NAD(P)H]
A flavoprotein (FAD). The enzyme from Corynebacterium cyclohexanicum is highly specific for 4-hydroxybenzoate, but uses NADH and NADPH at approximately equal rates (cf. EC 1.14.13.2 4-hydroxybenzoate 3-monooxygenase). It is less specific for NADPH than EC 1.14.13.2. Group: Enzymes. Synonyms: 4-hydroxybenzoate 3-monooxygenase (reduced nicotinamide adenine dinucleotide (phosphate)); 4-hydroxybenzoate-3-hydroxylase; 4-hydroxybenzoate 3-hydroxylase. Enzyme Commission Number: EC 1.14.13.33. CAS No. 95471-33-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0840; 4-hydroxybenzoate 3-monooxygenase [NAD(P)H]; EC 1.14.13.33; 95471-33-3; 4-hydroxybenzoate 3-monooxygenase (reduced nicotinamide adenine dinucleotide (phosphate)); 4-hydroxybenzoate-3-hydroxylase; 4-hydroxybenzoate 3-hydroxylase. Cat No: EXWM-0840.
4-hydroxybenzoate 4-O-β-D-glucosyltransferase
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. Group: Enzymes. Synonyms: uridine diphosphoglucose-4-hydroxybenzoate glucosyltransferase; UDP-glucose:4-(β-D-glucopyranosyloxy)benzoic acid glucosyltransferase; HBA glucosyltransferase; p-hydroxybenzoate glucosyltransferase; PHB glucosyltransferase; PHB-O-glucosyltransferase. Enzyme Commission Number: EC 2.4.1.194. CAS No. 120860-68-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2421; 4-hydroxybenzoate 4-O-β-D-glucosyltransferase; EC 2.4.1.194; 120860-68-6; uridine diphosphoglucose-4-hydroxybenzoate glucosyltransferase; UDP-glucose:4-(β-D-glucopyranosyloxy)benzoic acid glucosyltransferase; HBA glucosyltransferase; p-hydroxybenzoate glucosyltransferase; PHB glucosyltransferase; PHB-O-glucosyltransferase. Cat No: EXWM-2421.
4-hydroxybenzoate-CoA ligase
This enzyme belongs to the family of ligases, specifically those forming carbon-sulfur bonds as acid-thiol ligases. This enzyme participates in benzoate degradation via coa ligation. Group: Enzymes. Synonyms: 4-hydroxybenzoate-CoA synthetase; 4-hydroxybenzoate-coenzyme A ligase (AMP-forming); 4-hydroxybenzoyl coenzyme A synthetase; 4-hydroxybenzoyl-CoA ligase. Enzyme Commission Number: EC 6.2.1.27. CAS No. 119699-80-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5685; 4-hydroxybenzoate-CoA ligase; EC 6.2.1.27; 119699-80-8; 4-hydroxybenzoate-CoA synthetase; 4-hydroxybenzoate-coenzyme A ligase (AMP-forming); 4-hydroxybenzoyl coenzyme A synthetase; 4-hydroxybenzoyl-CoA ligase. Cat No: EXWM-5685.
4-hydroxybenzoate decarboxylase
This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. This enzyme participates in benzoate degradation via coa ligation. Group: Enzymes. Synonyms: p-hydroxybenzoate decarboxylase; 4-hydroxybenzoate carboxy-lyase. Enzyme Commission Number: EC 4.1.1.61. CAS No. 37290-53-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4808; 4-hydroxybenzoate decarboxylase; EC 4.1.1.61; 37290-53-2; p-hydroxybenzoate decarboxylase; 4-hydroxybenzoate carboxy-lyase. Cat No: EXWM-4808.
4-hydroxybenzoate geranyltransferase
The enzyme is involved in shikonin biosynthesis. It has a strict substrate specificity for geranyl diphosphate and an absolute requirement for Mg2+. Group: Enzymes. Synonyms: PGT1; PGT2; 4HB geranyltransferase; 4HB:geranyltransferase; p-hydroxybenzoate geranyltransferase; PHB geranyltransferase; geranyl diphosphate:4-hydroxybenzoate geranyltransferase. Enzyme Commission Number: EC 2.5.1.93. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2832; 4-hydroxybenzoate geranyltransferase; EC 2.5.1.93; PGT1; PGT2; 4HB geranyltransferase; 4HB:geranyltransferase; p-hydroxybenzoate geranyltransferase; PHB geranyltransferase; geranyl diphosphate:4-hydroxybenzoate geranyltransferase. Cat No: EXWM-2832.
4-hydroxybenzoate polyprenyltransferase
This enzyme, involved in the biosynthesis of ubiquinone, attaches a polyprenyl side chain to a 4-hydroxybenzoate ring, producing the first ubiquinone intermediate that is membrane bound. The number of isoprenoid subunits in the side chain varies in different species. The enzyme does not have any specificity concerning the length of the polyprenyl tail, and accepts tails of various lengths with similar efficiency. Group: Enzymes. Synonyms: nonaprenyl-4-hydroxybenzoate transferase; 4-hydroxybenzoate transferase; p-hydroxybenzoate dimethylallyltransferase; p-hydroxybenzoate polyprenyltransferase; p-hydroxybenzoic acid-polyprenyl transferase; p-hydroxybenzoic-polyprenyl transferase; 4-hydroxybenzoate nonaprenyltransferase. Enzyme Commission Number: EC 2.5.1.39. CAS No. 9030-77-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2775; 4-hydroxybenzoate polyprenyltransferase; EC 2.5.1.39; 9030-77-7; nonaprenyl-4-hydroxybenzoate transferase; 4-hydroxybenzoate transferase; p-hydroxybenzoate dimethylallyltransferase; p-hydroxybenzoate polyprenyltransferase; p-hydroxybenzoic acid-polyprenyl transferase; p-hydroxybenzoic-polyprenyl transferase; 4-hydroxybenzoate nonaprenyltransferase. Cat No: EXWM-2775.
4-hydroxybenzoyl-CoA reductase
A molybdenum-flavin-iron-sulfur protein that is involved in the anaerobic pathway of phenol metabolism in bacteria. A ferredoxin with two [4Fe-4S] clusters functions as the natural electron donor. Group: Enzymes. Synonyms: 4-hydroxybenzoyl-CoA reductase (dehydroxylating); 4-hydroxybenzoyl-CoA:(acceptor) oxidoreductase. Enzyme Commission Number: EC 1.3.7.9. CAS No. 133758-58-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1404; 4-hydroxybenzoyl-CoA reductase; EC 1.3.7.9; 133758-58-4; 4-hydroxybenzoyl-CoA reductase (dehydroxylating); 4-hydroxybenzoyl-CoA:(acceptor) oxidoreductase. Cat No: EXWM-1404.
4-hydroxybenzoyl-CoA thioesterase
This enzyme is part of the bacterial 2,4-dichlorobenzoate degradation pathway. Group: Enzymes. Enzyme Commission Number: EC 3.1.2.23. CAS No. 141583-19-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3558; 4-hydroxybenzoyl-CoA thioesterase; EC 3.1.2.23; 141583-19-9. Cat No: EXWM-3558.
4-hydroxybutanoyl-CoA dehydratase
Contains FAD and a [4Fe-4S] iron-sulfur cluster. The enzyme has been characterized from several microorganisms, including Clostridium kluyveri, where it participates in succinate fermentation, Clostridium aminobutyricum, where it participates in 4-aminobutyrate degradation, and Metallosphaera sedula, where it participates in the 3-hydroxypropionate/4-hydroxybutyrate cycle, an autotrophic CO2 fixation pathway found in some thermoacidophilic archaea. Group: Enzymes. Enzyme Commission Number: EC 4.2.1.120. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4961; 4-hydroxybutanoyl-CoA dehydratase; EC 4.2.1.120. Cat No: EXWM-4961.
4-hydroxybutyrate-CoA ligase
Isolated from the archaeon Metallosphaera sedula. Involved in the 3-hydroxypropanoate/4-hydroxybutanoate cycle. Group: Enzymes. Synonyms: 4-hydroxybutyrate-CoA synthetase; 4-hydroxybutyrate:CoA ligase (AMP-forming). Enzyme Commission Number: EC 6.2.1.40. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5699; 4-hydroxybutyrate-CoA ligase; EC 6.2.1.40; 4-hydroxybutyrate-CoA synthetase; 4-hydroxybutyrate:CoA ligase (AMP-forming). Cat No: EXWM-5699.
4-hydroxybutyrate dehydrogenase
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 4-hydroxybutanoate:NAD+ oxidoreductase. This enzyme is also called gamma-hydroxybutyrate dehydrogenase. This enzyme participates in butanoate metabolism and the degradation of the neurotransmitter 4-hydroxybutanoic acid. Group: Enzymes. Synonyms: γ-hydroxybutyrate dehydrogenase. Enzyme Commission Number: EC 1.1.1.61. CAS No. 9028-60-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0347; 4-hydroxybutyrate dehydrogenase; EC 1.1.1.61; 9028-60-8; γ-hydroxybutyrate dehydrogenase. Cat No: EXWM-0347.
4-hydroxycoumarin synthase
The enzyme, a polyketide synthase, can also accept benzoyl-CoA as substrate, which it condenses with 3 malonyl-CoA molecules to form 3,5-dihydroxybiphenyl (cf. EC 2.3.1.177, biphenyl synthase). Group: Enzymes. Synonyms: BIS2; BIS3. Enzyme Commission Number: EC 2.3.1.208. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2153; 4-hydroxycoumarin synthase; EC 2.3.1.208; BIS2; BIS3. Cat No: EXWM-2153.
4-hydroxycyclohexanecarboxylate dehydrogenase
The enzyme from Corynebacterium cyclohexanicum is highly specific for the trans-4-hydroxy derivative. Group: Enzymes. Synonyms: trans-4-hydroxycyclohexanecarboxylate dehydrogenase. Enzyme Commission Number: EC 1.1.1.226. CAS No. 67272-36-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0132; 4-hydroxycyclohexanecarboxylate dehydrogenase; EC 1.1.1.226; 67272-36-0; trans-4-hydroxycyclohexanecarboxylate dehydrogenase. Cat No: EXWM-0132.
4-hydroxyglutamate transaminase
Oxaloacetate can replace 2-oxoglutarate. This enzyme may be identical with EC 2.6.1.1 aspartate transaminase. Group: Enzymes. Synonyms: 4-hydroxyglutamate aminotransferase. Enzyme Commission Number: EC 2.6.1.23. CAS No. 37277-86-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2863; 4-hydroxyglutamate transaminase; EC 2.6.1.23; 37277-86-4; 4-hydroxyglutamate aminotransferase. Cat No: EXWM-2863.
4-hydroxymandelate oxidase
A flavoprotein (FMN). The enzyme from the bacterium Amycolatopsis orientalis is involved in the biosynthesis of L-(4-hydroxyphenyl)glycine and L-(3,5-dihydroxyphenyl)glycine, two non-proteinogenic amino acids occurring in the vancomycin group of antibiotics. Group: Enzymes. Synonyms: 4HmO; HmO. Enzyme Commission Number: EC 1.1.3.46. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0419; 4-hydroxymandelate oxidase; EC 1.1.3.46; 4HmO; HmO. Cat No: EXWM-0419.
4-hydroxymandelate oxidase (decarboxylating)
A flavoprotein (FAD), requires Mn2+. The enzyme from the bacterium Pseudomonas putida is involved in the degradation of mandelate. Group: Enzymes. Synonyms: L-4-hydroxymandelate oxidase (decarboxylating); (S)-2-hydroxy-2-(4-hydroxyphenyl)acetate:oxygen 1-oxidoreductase; (S)-4-hydroxymandelate:oxygen 1-oxidoreductase; 4-hydroxymandelate oxidase. Enzyme Commission Number: EC 1.1.3.19. CAS No. 60976-30-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0401; 4-hydroxymandelate oxidase (decarboxylating); EC 1.1.3.19; 60976-30-9; L-4-hydroxymandelate oxidase (decarboxylating); (S)-2-hydroxy-2-(4-hydroxyphenyl)acetate:oxygen 1-oxidoreductase; (S)-4-hydroxymandelate:oxygen 1-oxidoreductase; 4-hydroxymandelate oxidase. Cat No: EXWM-0401.
4-hydroxymandelate synthase
Requires Fe2+. Involved in the biosynthesis of the vancomycin group of glycopeptide antibiotics. Group: Enzymes. Synonyms: 4-hydroxyphenylpyruvate dioxygenase II. Enzyme Commission Number: EC 1.13.11.46. CAS No. 280566-04-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0564; 4-hydroxymandelate synthase; EC 1.13.11.46; 280566-04-3; 4-hydroxyphenylpyruvate dioxygenase II. Cat No: EXWM-0564.
4-(hydroxymethyl)benzenesulfonate dehydrogenase
Involved in the toluene-4-sulfonate degradation pathway in Comamonas testosteroni. Group: Enzymes. Enzyme Commission Number: EC 1.1.1.257. CAS No. 167973-64-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0162; 4-(hydroxymethyl)benzenesulfonate dehydrogenase; EC 1.1.1.257; 167973-64-0. Cat No: EXWM-0162.
4-hydroxymuconic-semialdehyde dehydrogenase
Involved in the 4-nitrophenol degradation pathway. Group: Enzymes. Enzyme Commission Number: EC 1.2.1.61. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1163; 4-hydroxymuconic-semialdehyde dehydrogenase; EC 1.2.1.61. Cat No: EXWM-1163.
4-hydroxyphenylacetaldehyde dehydrogenase
With EC 4.2.1.87 octopamine dehydratase, brings about the metabolism of octopamine in Pseudomonas. Group: Enzymes. Synonyms: 4-HPAL dehydrogenase. Enzyme Commission Number: EC 1.2.1.53. CAS No. 109456-56-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1157; 4-hydroxyphenylacetaldehyde dehydrogenase; EC 1.2.1.53; 109456-56-6; 4-HPAL dehydrogenase. Cat No: EXWM-1157.
4-hydroxyphenylacetaldehyde oxime monooxygenase
This enzyme is involved in the biosynthesis of the cyanogenic glucoside dhurrin in sorghum, along with EC 1.14.13.41, tyrosine N-monooxygenase and EC 2.4.1.85, cyanohydrin β-glucosyltransferase. Group: Enzymes. Synonyms: 4-hydroxybenzeneacetaldehyde oxime monooxygenase; cytochrome P450II-dependent monooxygenase; NADPH-cytochrome P450 reductase (CYP71E1); CYP71E1; 4-hydroxyphenylacetaldehyde oxime,NADPH:oxygen oxidoreductase. Enzyme Commission Number: EC 1.14.13.68. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0874; 4-hydroxyphenylacetaldehyde oxime monooxygenase; EC 1.14.13.68; 4-hydroxybenzeneacetaldehyde oxime monooxygenase; cytochrome P450II-dependent monooxygenase; NADPH-cytochrome P450 reductase (CYP71E1); CYP71E1; 4-hydroxyphenylacetaldehyde oxime,NADPH:oxygen oxidoreductase. Cat No: EXWM-0874.
4-hydroxyphenylacetate 1-monooxygenase
A flavoprotein (FAD). Also acts on 4-hydroxyhydratropate (forming 2-methylhomogentisate) and on 4-hydroxyphenoxyacetate (forming hydroquinone and glycolate). Group: Enzymes. Synonyms: 4-hydroxyphenylacetate 1-hydroxylase; 4-hydroxyphenylacetic 1-hydroxylase; 4-HPA 1-hydroxylase. Enzyme Commission Number: EC 1.14.13.18. CAS No. 55326-44-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0778; 4-hydroxyphenylacetate 1-monooxygenase; EC 1.14.13.18; 55326-44-8; 4-hydroxyphenylacetate 1-hydroxylase; 4-hydroxyphenylacetic 1-hydroxylase; 4-HPA 1-hydroxylase. Cat No: EXWM-0778.
4-hydroxyphenylacetate 3-monooxygenase
The enzyme from Escherichia coli attacks a broad spectrum of phenolic compounds. The enzyme uses FADH2 as a substrate rather than a cofactor. FADH2 is provided by EC 1.5.1.36, flavin reductase (NADH). Group: Enzymes. Synonyms: p-hydroxyphenylacetate 3-hydroxylase; 4-hydroxyphenylacetic acid-3-hydroxylase; p-hydroxyphenylacetate hydroxylase (FAD); 4 HPA 3-hydroxylase; p-hydroxyphenylacetate 3-hydroxylase (FAD); HpaB. Enzyme Commission Number: EC 1.14.14.9. CAS No. 37256-71-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0933; 4-hydroxyphenylacetate 3-monooxygenase; EC 1.14.14.9; 37256-71-6; p-hydroxyphenylacetate 3-hydroxylase; 4-hydroxyphenylacetic acid-3-hydroxylase; p-hydroxyphenylacetate hydroxylase (FAD); 4 HPA 3-hydroxylase; p-hydroxyphenylacetate 3-hydroxylase (FAD); HpaB. Cat No: EXWM-0933.
4-hydroxyphenylacetate decarboxylase
The enzyme, from the strict anaerobe Clostridium difficile, can also use (3,4-dihydroxyphenyl)acetate as a substrate, yielding 4-methylcatechol as a product. The enzyme is a glycyl radical enzyme. Group: Enzymes. Synonyms: p-hydroxyphenylacetate decarboxylase; p-Hpd; 4-Hpd; 4-hydroxyphenylacetate carboxy-lyase. Enzyme Commission Number: EC 4.1.1.83. CAS No. 340137-18-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4832; 4-hydroxyphenylacetate decarboxylase; EC 4.1.1.83; 340137-18-0; p-hydroxyphenylacetate decarboxylase; p-Hpd; 4-Hpd; 4-hydroxyphenylacetate carboxy-lyase. Cat No: EXWM-4832.
4-hydroxyphenylalkanoate adenylyltransferase
The mycobacterial enzyme participates in the biosynthesis of phenolphthiocerols. Following the substrate's activation by adenylation, it is transferred to an acyl-carrier protein domain within the enzyme, from which it is transferred to the phenolphthiocerol/phthiocerol polyketide synthase. Group: Enzymes. Synonyms: fadD29 (gene name); 4-hydroxyphenylalkanoate adenylase. Enzyme Commission Number: EC 2.7.7.94. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3308; 4-hydroxyphenylalkanoate adenylyltransferase; EC 2.7.7.94; fadD29 (gene name); 4-hydroxyphenylalkanoate adenylase. Cat No: EXWM-3308.
The enzyme is involved in the biosynthesis of the 3-dimethylallyl-4-hydroxyphenylpyruvate moiety of the aminocoumarin antibiotics clorobiocin and novobiocin. Group: Enzymes. Synonyms: CloQ; 4HPP dimethylallyltransferase; NovQ. Enzyme Commission Number: EC 2.5.1.111. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2727; 4-hydroxyphenylpyruvate 3-dimethylallyltransferase; EC 2.5.1.111; CloQ; 4HPP dimethylallyltransferase; NovQ. Cat No: EXWM-2727.