MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Cholesteryl sulfate sodium | Cholesteryl sulfate sodium is an orally available, NPC2 -targeted cholesterol biosynthesis agonist. Cholesteryl sulfate sodium activates SREBP2 by competitively binding to NPC2, promoting cholesterol synthesis ( EC 50 =50 μM). Cholesteryl sulfate sodium enhances the self-assembly ability of Mitoxantrone hydrochloride (HY-13502A), while repairing the intestinal mucosal barrier and inhibiting inflammation by regulating serine protease activity and PKCη signaling pathway. Cholesteryl sulfate sodium is a component of the platelet cell membrane and supports platelet adhesion. Cholesteryl sulfate sodium also regulates the activity of selective protein kinase C isoforms and modulates the specificity of PI3K, playing a role in keratinocyte differentiation [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 2864-50-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111355B. |  |
| Cholestyramine | Cholestyramine (Colestyramine) is a bile acid binding resin and can inhibit intestinal bile acid absorption which results in the increasing bile acid synthesis from cholesterol. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Cholestyramine resin; Colestyramine. CAS No. 11041-12-6. Pack Sizes: 500 mg; 1 g. Product ID: HY-104081. | |
| Cholic acid | Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid is orally active [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 81-25-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 1 g. Product ID: HY-N0324. | |
| Cholic acid 7-sulfate | Cholic acid 7-sulfate (7-Sulfocholic acid), a metabolite of Cholic acid, is a Takeda G-protein receptor 5 (TGR5) agonist. Cholic acid 7-sulfate can increase Tgr5 expression and induce GLP-1 secretion [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 7-Sulfocholic acid. CAS No. 60320-05-0. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-126855. | |
| Cholic acid-d4 | Cholic acid-d 4 is the deuterium labeled Cholic acid. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 116380-66-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0324S. | |
| Cholic acid sodium | Cholic acid sodium is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid sodium is orally active [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Sodium cholate. CAS No. 361-09-1. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-N0324A. | |
| Choline bitartrate | Choline bitartrate is a vitamin-like essential nutrient , can affect diseases such as liver disease, atherosclerosis and neurological disorders [1] [2]. Choline bitartrate is a precursor for the neurotransmitter acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism [3]. Uses: Scientific research. Group: Natural products. CAS No. 87-67-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-101036. | |
| Choline chloride | Choline chloride is an essential nutrient that activates alpha7 nicotinic receptors and has analgesic and anti-inflammatory activity. Glycerophosphoinositol choline can affect diseases such as liver disease, atherosclerosis and neurological disorders [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 67-48-1. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1337. | |
| Choline Fenofibrate | Choline Fenofibrate (ABT-335), a choline salt of Fenofibric acid (HY-B0760), releases free Fenofibric acid in the gastrointestinal tract. Fenofibric acid is a PPAR activator with antihyperlipidemic effect [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-335. CAS No. 856676-23-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14739. | |
| Choline oxidase | Choline oxidase (EC 1.1.3.17) catalyzes the oxidation of choline to glycine betaine via betaine aldehyde in glycine betaine biosynthesis and betaine acts as an osmolyte. Choline oxidase has potential in enzymatic betaine production [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9028-67-5. Pack Sizes: 100 U. Product ID: HY-P2743. | |
| Cholinesterase, Horse serum | Cholinesterase, Horse serum infers to acetylcholinesterase (AChE) and butyryl cholinesterase (BChE). AChE and BChE catalyze the hydrolysis of 6-MAM to morphine [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EC 3.1.1.8; BCHE, Horse serum. CAS No. 9001-8-5. Pack Sizes: 100 U. Product ID: HY-P2798. | |
| Choline theophyllinate | Choline theophyllinate (Oxtriphylline) is a choline salt of theophylline with anti-asthmatic activity [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Oxtriphylline. CAS No. 4499-40-5. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B1718. | |
| Choline tosylate | Choline tosylate is a nucleophilic compound that inhibits phospholipase A2 and phospholipase C. Choline tosylate inhibits tumor growth in mice by inhibiting the formation of diacylglycerol (DAG) [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Choline p-toluenesulfonate. CAS No. 55357-38-5. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g. Product ID: HY-W100403. | |
| Choloylglycine hydrolase | Choloylglycine hydrolase is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Signaling pathways. CAS No. 37289-07-9. Pack Sizes: 3 KU. Product ID: HY-P2958. | |
| Chondroitinase ABC | Chondroitinase ABC (ChABC) is an enzyme that degrades glycosaminoglycan side-chains of chondroitin sulfate (CS-GAG) from the chondroitin sulfate proteoglycan (CSPG) core protein. Chondroitinase ABC facilitates reinnervation by degrading CS-GAGs around motoneurons. Chondroitinase ABC has the potential for the research of spinal injury [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ChABC. CAS No. 9024-13-9. Pack Sizes: 2 U. Product ID: HY-P2727. | |
| Chondroitin sulfate | Chondroitin sulfate, one of five classes of glycosaminoglycans, has been widely used in the treatment of osteoarthritis. Chondroitin sulfate reduces inflammation mediators and the apoptotic process and is able to reduce protein production of inflammatory cytokines, iNOS and MMPs. Uses: Scientific research. Group: Natural products. Alternative Names: Chondroitin polysulfate. CAS No. 9007-28-7. Pack Sizes: 250 mg; 1 g. Product ID: HY-B2162. | |
| Chondroitin sulfate (from bovine) | Chondroitin sulfate from Bovine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Chondroitin polysulfate sulfate (from bovine). CAS No. 9007-28-7. Pack Sizes: 100 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B2162B. | |
| Chondroitin sulfate (from chicken) | Chondroitin sulfate from Chicken is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Chondroitin polysulfate sulfate (from chicken). CAS No. 9007-28-7. Pack Sizes: 5 g. Product ID: HY-B2162D. | |
| Chorionic gonadotrophin | Chorionic gonadotrophin (hCG) is a gonadotropin that can be isolated from the anterior pituitary gland. Chorionic gonadotrophin has potential applications in ovarian and follicular development [1]. Uses: Scientific research. Group: Natural products. Alternative Names: hCG; Chorionic gonadotropic hormone. CAS No. 9002-61-3. Pack Sizes: 5000 U. Product ID: HY-107953. | |
| Chromium(III) acetate | Chromium(III) acetate (Chromic acetate) is an AMPK inhibitor that promotes lipogenesis by inhibiting AMPK phosphorylation. Chromium(III) acetate has low toxicity in mammals, with an LD 50 of 2365 mg/kg in rats [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Chromium acetate; Chromic acetate; Chromium triacetate. CAS No. 1066-30-4. Pack Sizes: 5 g; 10 g. Product ID: HY-D1163. | |
| Chromium picolinate | Chromium picolinate (Chromium (III) picolinate) is a compound that has oral activity. Chromium picolinate induces apoptosis. Chromium picolinate is the activator of p38 MAPK. Chromium picolinate has antioxidant activity. Chromium picolinate can be used in research on type 2 diabetes [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Chromium (III) picolinate; Cr(Pic)3. CAS No. 14639-25-9. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-125588. | |
| Chromomycin A3 | Chromomycin A3 is an aureolic acid-type antitumor antibiotic. Chromomycin A3 forms dimeric complexes with divalent cations, such as Mg 2+ , which strongly binds to the GC rich sequence of DNA to inhibit DNA replication and transcription. Chromomycin A3 has a variety of utilities as a staining agent for human sperm chromatin, autophagy inducing agent, and apoptosis inhibitor [1]. Uses: Scientific research. Group: Natural products. CAS No. 7059-24-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W040129. | |
| Chrysene | Chrysene is a high molecular weight (HMW), polycyclic aromatic hydrocarbon (PAH) known for its recalcitrance and carcinogenic properties [1]. Uses: Scientific research. Group: Natural products. CAS No. 218-01-9. Pack Sizes: 500 mg. Product ID: HY-121107. | |
| Chrysene-d12 | Chrysene-d 12 is the deuterium labeled Chrysene. Chrysene is a high molecular weight (HMW), polycyclic aromatic hydrocarbon (PAH) known for its recalcitrance and carcinogenic properties[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1719-03-5. Pack Sizes: 50 mg; 100 mg. Product ID: HY-121107S. | |
| Chrysin | Chrysin is one of the most well known estrogen blockers. Uses: Scientific research. Group: Natural products. Alternative Names: 5,7-Dihydroxyflavone. CAS No. 480-40-0. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-14589. | |
| Chrysin-7-O-glucuronide | Chrysin-7-O-glucuronide is a flavonoid extracted from Scutellaria baicalensis , with antioxidant activity [1]. Uses: Scientific research. Group: Natural products. CAS No. 35775-49-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N2376. | |
| Chrysin (Standard) | Chrysin (Standard) is the analytical standard of Chrysin. This product is intended for research and analytical applications. Chrysin is one of the most well known estrogen blockers. Uses: Scientific research. Group: Natural products. CAS No. 480-40-0. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14589R. | |
| Chrysoeriol | Chrysoeriol is a kind of natural yellow ash, which can be used for heating plants Coronopus didymus. Chrysoeriol suppresses the JAK2/STAT3, IκB/p65, and NF-κB pathways, and has strong anti-inflammatory activity [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 491-71-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-121471. | |
| Chrysomycin A | Chrysomycin A (Chr-A), an antibiotic, can be obtained from Streptomyces. Chrysomycin A exhibits antitumor and anti-tuberculous and MRSA activities. As for glioblastoma, Chrysomycin A inhibits the proliferation, migration, and invasion of cancer cells through the Akt/GSK-3β/β-catenin signaling pathway [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Chr-A. CAS No. 82196-88-1. Pack Sizes: 250 μg. Product ID: HY-126771. | |
| Chrysophanol | Chrysophanol (Chrysophanic acid) is a natural anthraquinone, which inhibits EGF-induced phosphorylation of EGFR and suppresses activation of AKT and mTOR / p70S6K. Uses: Scientific research. Group: Natural products. Alternative Names: Chrysophanic acid. CAS No. 481-74-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-13595. | |
| Chrysophanol 8-O-glucoside | Chrysophanol 8-O-glucoside, from the roots of Rumex acetosa , shows moderate elastase inhibition activity [1]. Uses: Scientific research. Group: Natural products. CAS No. 13241-28-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N2395. | |
| Chrysosplenetin | Chrysosplenetin is one of the polymethoxylated flavonoids in Artemisia annua L. (Compositae) and other several Chinese herbs. Chrysosplenetin inhibits P-gp activity and reverses the up-regulated P-gp and MDR1 levels induced by artemisinin (ART). Chrysosplenetin significantly augments the rat plasma level and anti-malarial efficacy of ART, partially due to the uncompetitive inhibition effect of Chrysosplenetin on rat CYP3A [1]. Uses: Scientific research. Group: Natural products. CAS No. 603-56-5. Pack Sizes: 5 mg; 10 mg; 20 mg. Product ID: HY-N1457. | |
| Chymopapain | Chymopapain is a non-specific proteo-glycanase derived from the papaya plant. Chymopapain directly into the intervertebral disc caused disc narrowing due to dissolution of the extruded material. Chymopapain has the potential for the research of herniated lumbar discs [1]. Uses: Scientific research. Group: Natural products. CAS No. 9001-9-6. Pack Sizes: 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-108909. | |
| Chymostatin | Chymostatin is a SARS-CoV-2 M pro inhibitor. Chymostatin up-regulates endocan and inhibits NF-κBp65 activity. Chymostatin reduces proinflammatory cytokines ( IL-1β and IL-6 ) and HMGB1. Chymostatin shows protective effects against Paraquat-induced acute lung injury. Chymostatin exhibits anticancer activity against lung cancer [1] [2] [3] [4] [5] [6] [7]. Uses: Scientific research. Group: Peptides. CAS No. 9076-44-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P3042. | |
| Chymotrypsin | Chymotrypsin (Chymotrypsin A) is a serine protease produced by the pancreas. Chymotrypsin cleaves protein chains at the carboxyl side of aromatic amino acids [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: EC 3.4.21.1; Chymotrypsin A. CAS No. 9004-7-3. Pack Sizes: 500 mg; 1 g. Product ID: HY-108910. | |
| CI-1040 | CI-1040 (PD 184352) is an orally active, highly specific, small-molecule inhibitor of MEK with an IC 50 of 17 nM for MEK1. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PD 184352. CAS No. 212631-79-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-50295. | |
| CI-966 hydrochloride | CI-966 hydrochloride is a potent, selective, orally active and brain-penetrant inhibitor of the GABA transporter GAT-1 , with IC 50 s of 0.26 μM and 1.2 μM for hGAT-1 , rGAT-1 , respectively. CI-966 hydrochloride shows more than 200-fold selectivity over GAT-2, GAT-3, and BGT-3. CI-966 hydrochloride exhibits anticonvulsant and neuroprotective activities [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 110283-66-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-103534. | |
| Cibacron Blue 3G-A | Cibacron Blue 3G-A is an anthraquinone dye , inhibits the R46 β-lactamase with a K i value of 1.2 uM [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 84166-13-2. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129042. | |
| Cibenzoline | Cibenzoline is a class Ia antiarrhythmic active molecule with low anticholinergic activity. Cibenzoline is a K ATP channel inhibitor, acting through the pore forming subunit Kir6.2, with an IC 50 of 22.2 μM. Cibenzoline inhibits I Kr and I Ks currents with IC 50 values of 8.8 μM and 12.3 μM, respectively. Cibenzoline is used in the study of cardiac diseases. In addition, Cibenzoline can induce hypoglycemia [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Cifenline; Ro 22-7796. CAS No. 53267-01-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106577. | |
| Cibinetide | Cibinetide (ARA290) is an EPO-derivative, acting as a specific agonist of erythropoietin/CD131 heteroreceptor, and used for neurological disease treatment. Uses: Scientific research. Group: Peptides. Alternative Names: ARA290. CAS No. 1208243-50-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P0168. | |
| Ciclesonide | Ciclesonide (RPR251526) is a glucocorticoid with an potent anti-inflammatory activity. Ciclesonide can be used for asthma research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RPR251526. CAS No. 126544-47-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0625. | |
| Ciclopirox | Ciclopirox (HOE296b) is a synthetic and orally active antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes , yeasts , molds , and many Gram-positive and Gram-negative species pathogenic. Ciclopirox also has anticancer and anti-inflammatory effect [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HOE296b. CAS No. 29342-05-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B0450. | |
| Ciclopirox olamine | Ciclopirox olamine (Ciclopirox ethanolamine) is a synthetic and orally active antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes , yeasts , molds , and many Gram-positive and Gram-negative species pathogenic. Ciclopirox olamine also has anticancer and anti-inflammatory effect [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ciclopirox ethanolamine; HOE 296. CAS No. 41621-49-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B0450A. | |
| CID 16020046 | CID 16020046 is a potent and selective GPR55 antagonist and inhibits GPR55 constitutive activity with an IC 50 of 0.15 μM. CID 16020046 inhibits GPR55-mediated Ca 2+ signaling and GPR55-mediated ERK1/2 phosphorylation. CID 16020046 reduces wound healing in endothelial cells and is involved in the regulation of platelet function [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 834903-43-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16697. | |
| CID 697851 | CID 697851 is an AddAB and RecBCD inhibitor, with IC 50 s of 13 and 33 nM. CID 697851 can be used for antibacterial research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 312508-42-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-151221. | |
| Cidofovir | Cidofovir (GS 0504) is an acyclic monophosphate nucleotide analogue and CMV inhibitor with antiviral activity. Cidofovir inhibits cytomegalovirus (CMV) replication by selectively inhibiting viral DNA polymerase. Cidofovir induces apoptosis and can be used in studies of AIDS cytomegalovirus retinitis, herpes, and cancer [1] [3]. Cidofovir also has anti- orthopoxvirus and anti-variola activities [4]. Uses: Scientific research. Group: Natural products. Alternative Names: GS 0504; HPMPC; (S)-HPMPC. CAS No. 113852-37-2. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17438. | |
| Ciforadenant | Ciforadenant (CPI-444) is a potent, orally active and selective adenosine A2A receptor ( A2AR ) antagonist, which induces antitumor responses [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CPI-444; V81444. CAS No. 1202402-40-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101978. | |
| Ciglitazone | Ciglitazone is a potent and selective PPARγ agonist ( EC 50 =3 μM). Ciglitazone inhibits proliferation and differentiation of th17 cells. Ciglitazone is a hypoglycemic agent orally active in the obese-hyperglycemic animal models. Ciglitazone induces apoptosis accompanied by activation of p38 MAPK and nuclear translocation of apoptosis inducing factor (AIF) in opossum kidney (OK) renal epithelial cells [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ADD-3878; U-63287. CAS No. 74772-77-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W011220. | |
| Cilastatin | Cilastatin (MK0791) is a reversible, competitive renal dehydropeptidase I inhibitor with an IC 50 of 0.1 μM. Cilastatin inhibits the bacterial metallob-lactamase enzyme CphA with an IC 50 of 178 μM. Cilastatin is an antibacterial adjunct [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK0791. CAS No. 82009-34-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-A0166. | |
| Cilastatin sodium | Cilastatin sodium (MK0791 sodium) is a reversible, competitive renal dehydropeptidase I inhibitor with an IC 50 of 0.1 μM. Cilastatin sodium inhibits the bacterial metallob-lactamase enzyme CphA with an IC 50 of 178 μM. Cilastatin sodium is an antibacterial adjunct [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK0791 sodium. CAS No. 81129-83-1. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-A0166A. | |
| Cilazapril monohydrate | Cilazapril Monohydrate is a angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and congestive heart failure. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro 31-2848 monohydrate. CAS No. 92077-78-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0043A. | |
| Cilgavimab | Cilgavimab (AZD-1061; COV2-2130) is a human SARS-CoV-2 -neutralizing monoclonal antibody, can compose monoclonal-antibody combination AZD7442 with Tixagevimab (HY-P99556). Cilgavimab shows protective action on mouse models of SARS-CoV-2 infection [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AZD-1061; COV2-2130. CAS No. 2420563-99-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99604. | |
| Cilnidipine | Cilnidipine is a long-acting, second-generation dihydropyridine Ca 2+ -channel blocker on L and N-type Ca 2+ channel [1] [2] [3] [4]. Antihypertensive effects [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FRC-8653. CAS No. 132203-70-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17404. | |
| Cilofexor | Cilofexor (GS-9674) is a potent, selective and orally active nonsteroidal FXR agonist with an EC 50 of 43 nM. Cilofexor has anti-inflammatory and antifibrotic effects. Cilofexor has the potential for primary sclerosing cholangitis (PSC) and nonalcoholic steatohepatitis (NASH) research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-9674. CAS No. 1418274-28-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109083. | |
| Cilomilast | Cilomilast (SB-207499) is a potent, selective and orally active inhibitor of Phosphodiesterase 4 (PDE4) , with IC 50 s of ~100 and 120 nM for LPDE4 and HPDE4, respectively. Cilomilast shows selectivity for PDE4 over PDE1, PDE2, PDE3 and PDE5 ( IC 50=74, 65, >100, and 83 μM, respectively). Cilomilast has anti-inflammatory and immunomodulatory effects and can be used for thr research of asthma and chronic obstructive pulmonary disease (COPD) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SB-207499. CAS No. 153259-65-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10790. | |
| Cilostazol | Cilostazol (OPC 13013) is a potent and selective inhibitor of phosphodiesterase (PDE) 3A , the isoform of PDE 3 in the cardiovascular system, with an IC 50 of 0.2 μM [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: OPC 13013. CAS No. 73963-72-1. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-17464. | |
| CIM0216 | CIM0216, a synthetic TRPM3 ligand, acts as a potent and selective agonist of TRPM3. CIM0216 exhibits selectivity for TRPM3 over TRPM1, TRPM2 and TRPM4-8. CIM0216 acts in a TRPM3-dependent manner to induce pain and evoke neuropeptide release from sensory nerve terminals in vitro. CIM0216 is a powerful tool for studies of the physiological functions of TRPM3, and can be used for neurogenic inflammation research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1031496-06-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110220. | |
| Cimetidine | Cimetidine (SKF-92334) is an orally active and inverse histamine H2 receptor antagonist with a K i of 0.6 μM. Cimetidine is a gastric acid reducer, and can be used for duodenal and gastric ulcers research. Cimetidine has anti-cancer and anti-inflammatory activity [1] [2] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SKF-92334. CAS No. 51481-61-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 1 g; 5 g; 10 g. Product ID: HY-14289. | |
| Cimetropium Bromide | Cimetropium Bromide (DA-3177) is a mAChR antagonist for long-term treatment of irritable bowel syndrome. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DA-3177. CAS No. 51598-60-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-U00106. | |
| Cimicoxib | Cimicoxib (CX) is an orally active potent and selective COX-2 (cyclo-oxygenase-2) inhibitor. Cimicoxib exhibits promising anti-inflammatory and analgesic activity. The PK parameters of Cimicoxib in dogs given precise (2 mg/kg) and approximate doses (1.95-2.5 mg/kg) are similar [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UR-8880. CAS No. 265114-23-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-100516. | |
| Cimlanod | Cimlanod (BMS-986231) is a second-generation Nitroxyl (HNO) donor for heart failure. Cimlanod (BMS-986231) delivers HNO via pH-dependent chemical breakdown when exposed to the neutral pH environment of the bloodstream. Cimlanod (BMS-986231) possesses positive lusitropic and inotropic as well as vasodilatory effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-986231; CXL-1427. CAS No. 1620330-72-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-118643. | |
| Cinacalcet | Cinacalcet (AMG 073) is an orally active, allosteric agonist of Ca receptor (CaR) , used for cardiovascular disease research. Uses: Scientific research. Group: Natural products. Alternative Names: AMG 073. CAS No. 226256-56-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-70037. | |
| Cinacalcet hydrochloride | Cinacalcet hydrochloride (AMG-073 hydrochloride) is an orally active, allosteric agonist of Ca receptor (CaR) , used for cardiovascular disease treatment. Uses: Scientific research. Group: Natural products. Alternative Names: AMG-073 hydrochloride. CAS No. 364782-34-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-70037A. | |
| Cinaciguat | Cinaciguat is an activator of guanylate cyclase (sGC) , and used for acute decompensated heart failure. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 58-2667. CAS No. 329773-35-5. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14181. | |
| Cinaciguat hydrochloride | Cinaciguat hydrochloride is a potent soluble guanylate cyclase ( GC ) activator with EC 50 of 15 nM in platelets. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 58-2667 hydrochloride. CAS No. 646995-35-9. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14181A. | |
| Cinanserin hydrochloride | Cinanserin hydrochloride (SQ 10643) is a potent, selective and highly affinity 5-HT 2 receptor antagonist with a K i of 41 nM. Cinanserin hydrochloride has a much higher binding affinity for the 5-HT 2 than for the 5-HT 1 receptor ( K i of 3500 nM). Cinanserin is also an inhibitor of 3C-like proteinase of severe acute respiratory syndrome coronavirus and strongly reduces virus replication in vitro [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SQ 10643. CAS No. 54-84-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100943. | |
| Cinchonidine | Cinchonidine (α-Quinidine) is a cinchona alkaloid found in Cinchona officinalis and Gongronema latifolium. A building block used in asymmetric synthesis in organic chemistry. Weak inhibitor of serotonin transporter (SERT) with K i s of 330, 4.2, 36, 196, 15 μM for dSERT, hSERT, hSERT I172M, hSERT S438T, hSERT Y95F, respectively. Antimalarial activities [1]. Uses: Scientific research. Group: Natural products. Alternative Names: α-Quinidine. CAS No. 485-71-2. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-N0173. | |
| Cinchonine | Cinchonine is a natural compound present in Cinchona bark with antimalarial, antitumor, anti-inflammatory, anti platelet-aggregation and anti-obesity properties. Cinchonine inhibits cells proliferation and autophagy and induces apoptosis through activation of Caspase-3. Cinchonine activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells [1]. Uses: Scientific research. Group: Natural products. Alternative Names: (8R,9S)-Cinchonine; LA40221. CAS No. 118-10-5. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-Y0152. | |
| Cinepazide Maleate | Cinepazide Maleate (MD-67350) is a piperazine derivative and acts as a weak calcium channel blocker. Cinepazide Maleate is a potent vasodilator and can be used for the research of cerebrovascular diseases, including ischemic stroke, brain infarct et. al [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MD-67350. CAS No. 26328-04-1. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-66010. | |
| Cinitapride | Cinitapride is a nonselective 5-HT1 and 5-HT4 receptors agonist and a 5-HT2 and D2 antagonist. Cinitapride can be used in functional dyspepsia (FD) and gastroesophageal reflux disease (GERD) research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 66564-14-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B2089. | |
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