MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Bursin | Bursin is a peptide that can be isolated from the bursa of Fabricius of chicken. Bursin induces the phenotypic differentiation of mammalian and avian B precursor cells. Bursin also increases cyclic guanosine monophosphate in cells of the human B-cell line Daudi, its derivatives are able to protect against infection by amplifying the immune response induced by H9N2 [1]. Uses: Scientific research. Group: Peptides. CAS No. 60267-34-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-125153. |  |
| Buspirone | Buspirone is an orally active 5-HT1A receptor agonist, and a dopamine D2 autoreceptorsant antagonist. Buspirone is an anxiolytic agent, and can be used for the generalized anxiety disorder research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 36505-84-7. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1115A. | |
| Buspirone hydrochloride | Buspirone hydrochloride is a 5-HT1A receptor agonist. Buspirone hydrochloride can be used for anxiety and depression research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 33386-08-2. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1115. | |
| Busulfan | Busulfan is a potent alkylating antineoplastic agent. Busulfan causes DNA damage by cross-linking DNAs and DNA and proteins. Busulfan inhibits thioredoxin reductase. Busulfan induces apoptosis. Busulfan is an immunosuppressive and myeloablative chemotherapeutic agent [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 55-98-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-B0245. | |
| Busulfan-d8 | Busulfan-d 8 is a deuterium labeled Busulfan. Busulfan is a potent alkylating antineoplastic agent. Busulfan causes DNA damage by cross-linking DNAs and DNA and proteins. Busulfan inhibits thioredoxin reductase. Busulfan induces apoptosis. Busulfan is an immunosuppressive and myeloablative chemotherapeutic agent[1][2][3]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 116653-28-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-B0245S. | |
| Butabindide oxalate | Butabindide (UCL-1397) oxalate is a potent, selective tripeptidvl peptidase II (TPP II) inhibitor with K i values of 7 nM and 10 μM for TPP II and TPP I, respectively. Butabindide oxalate inhibits TPP II to protect CCK-8 against inactivation [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UCL-1397 oxalate. CAS No. 185213-03-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-107759. | |
| Butacaine | Butacaine is a reversible nerve conduction blocker. Butacaine acts on the nervous system and nerve fibers, can cause both sensory and motor paralysis. Butacaine inhibits the NavBh currents [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 149-16-6. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1007. | |
| Butachlor | Butachlor is an herbicide of the acetanilide class. Butachlor is used as a selective pre-emergent herbicide [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 23184-66-9. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-B2042. | |
| Butamben | Butamben (Butyl 4-aminobenzoate) results in long-lasting relief from pain, without impairing motor function or other sensory functions [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Butyl 4-aminobenzoate. CAS No. 94-25-7. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g. Product ID: HY-B1430. | |
| Butamirate citrate | Butamirate citrate is an orally active cough suppressant that acts centrally through the receptors in the brainstem. Butamirate citrate also reduces the resistance in the airways by inhibiting bronchospasm and anti-inflammatory effect [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 18109-81-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118545A. | |
| Butanoyl PAF | Butanoyl PAF, a compound closely related to Azelaoyl PC (HY-134154), maintains over 10% of the agonist potency of platelet-activating factor ( PAF ). Butanoyl PAF's concentration in oxidized low-density lipoprotein surpasses that of enzymatically generated PAF by more than 100-fold [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 85405-03-4. Pack Sizes: 1 mg. Product ID: HY-W040221. | |
| Butaxamine hydrochloride | Butaxamine (Butoxamin) hydrochloride is a specific β2- adrenergic receptor blocker. Butaxamine hydrochloride inhibits the decreases in urine volume in ethanol-anesthetized, water-diuretic rats [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Butoxamin hydrochloride. CAS No. 5696-15-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-118470. | |
| Butein | Butein is a cAMP-specific PDE inhibitor with an IC 50 of 10.4 μM for PDE4 [1]. Butein is a specific protein tyrosine kinase inhibitor with IC 50 s of 16 and 65 μM for EGFR and p60 c-src in HepG2 cells [2]. Butein sensitizes HeLa cells to Cisplatin through AKT and ERK/p38 MAPK pathways by targeting FoxO3a [3]. Butein is a SIRT1 activator (STAC). Uses: Scientific research. Group: Natural products. Alternative Names: 2,3,4,4-tetrahydroxy Chalcone. CAS No. 487-52-5. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16558. | |
| Butenafine Hydrochloride | Butenafine Hydrochloride (KP363 Hydrochloride) is a synthetic benzylamine antifungal, works by inhibiting the synthesis of sterols by inhibiting squalene epoxidase. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KP363 Hydrochloride. CAS No. 101827-46-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-17396. | |
| Butin | Butin is a major biologically active flavonoid isolated from the heartwood of Dalbergia odorifera with oral activity, with strong antioxidant, antiplatelet and anti-inflammatory activities. Butin significantly alleviates myocardial infarction and improves heart function, together with prevents diabetes-induced cardiac oxidative damage in rat [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 21913-99-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N6020B. | |
| (-)-Butin | (-)-Butin is the S enantiomer of Butin. Butin is a major biologically active flavonoid isolated from the heartwood of Dalbergia odorifera , with strong antioxidant, antiplatelet and anti-inflammatory activities [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 492-14-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N6020. | |
| (+)-Butin | (+)-Butin is the R enantiomer of Butin. Butin is a major biologically active flavonoid isolated from the heartwood of Dalbergia odorifera, with strong antioxidant, antiplatelet and anti-inflammatory activities [1]. Uses: Scientific research. Group: Natural products. CAS No. 74628-42-5. Pack Sizes: 10 mM * 1 mL; 5 mg. Product ID: HY-N6020A. | |
| Butoconazole | Butoconazole, an imidazole antifungal agent, is active against Candida spp. and effective against vaginal infections due to Candida albicans. Butoconazole is presumed to function as other imidazole derivatives via inhibition of steroid synthesis [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 64872-76-0. Pack Sizes: 25 mg; 50 mg. Product ID: HY-B0293A. | |
| Butoconazole nitrate | Butoconazole nitrate (RS 35887), an imidazole antifungal agent, is active against Candida spp. and effective against vaginal infections due to Candida albicans. Butoconazole nitrate is presumed to function as other imidazole derivatives via inhibition of steroid synthesis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RS 35887. CAS No. 64872-77-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg. Product ID: HY-B0293. | |
| Butralin | Butralin is a widely used dinitroaniline herbicide [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 33629-47-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-121331. | |
| Butylated hydroxytoluene | Butylated hydroxytoluene is an antioxidant widely used in foods and in food-related products [1]. Butylated hydroxytoluene is a Ferroptosis inhibitor [2]. Uses: Scientific research. Group: Natural products. CAS No. 128-37-0. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-Y0172. | |
| Butylboronic acid | Butylboronic acid is a competitive soybean urease inhibitor with an IC 50 of 2.9 mM and a K i of 1.5 mM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 4426-47-5. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-W000932. | |
| Butyl isobutyl phthalate | Butyl isobutyl phthalate is isolated from the rhizoid of Laminaria japonica. Butyl isobutyl phthalate is a non-competitive α-glucosidase inhibitor with an IC 50 value of 38 μM. Butyl isobutyl phthalate shows a hypoglycemic effect and has the potential for diabetes treatment [1]. Uses: Scientific research. Group: Natural products. CAS No. 17851-53-5. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N7377. | |
| Butylparaben | Butylparaben is an organic compound that has proven to be a very successful antimicrobial preservative in cosmetics, can also be used in active molecule suspensions, and as a food flavoring additive [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Butyl parahydroxybenzoate; Butyl paraben; Butyl 4-hydroxybenzoate. CAS No. 94-26-8. Pack Sizes: 10 mM * 1 mL; 10 g; 25 g. Product ID: HY-B1431. | |
| Butylparaben (Standard) | Butylparaben (Standard) is the analytical standard of Butylparaben. This product is intended for research and analytical applications. Butylparaben is an organic compound that has proven to be a very successful antimicrobial preservative in cosmetics, can also be used in active molecule suspensions, and as a food flavoring additive [1]. Uses: Scientific research. Group: Natural products. CAS No. 94-26-8. Pack Sizes: 50 mg; 100 mg; 250 mg. Product ID: HY-B1431R. | |
| Butylphthalide | Butylphthalide (3-n-Butylphthalide) is an active molecule against cerebral ischemia. It was originally isolated from celery species and has been shown to be effective in stroke animal models. Uses: Scientific research. Group: Natural products. Alternative Names: 3-n-Butylphthalide; 3-Butylphthalide. CAS No. 6066-49-5. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B0647. | |
| Butyramide | Butyramide is a biochemical reagent that can be used as a biological material or organic compound for life science related research [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Butyramide. CAS No. 541-35-5. Pack Sizes: 25 g. Product ID: HY-W088319. | |
| Butyrolactone 3 | Butyrolactone 3 (MB-3) is a specifical small-molecule inhibitor of the histone acetyltransferase Gcn5 (IC50=100 ?M), which has a high affinity to the Gcn5 enzyme comparable to that of its natural substrate, histone H3. Butyrolactone 3 shows weak inhibitory on CBP (IC50=0.5 mM). Butyrolactone 3 can be used in studies of cancer, metabolic, autoimmune and neurological diseases[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MB-3. CAS No. 778649-18-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-129039. | |
| Butyrylcarnitine | Butyrylcarnitine is a metabolite in plasma, acts as a biomarker to improve the diagnosis and prognosis of heart failure, and is indicative of anomalous lipid and energy metabolism. Uses: Scientific research. Group: Natural products. CAS No. 25576-40-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113168. | |
| Butyrylcholine chloride | Butyrylcholine (chloride) is a biochemical assay reagent. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 2963-78-2. Pack Sizes: 50 mg. Product ID: HY-W014419. | |
| Butyrylcholine iodide | Butyrylcholine Iodide is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 2494-56-6. Pack Sizes: 100 mg. Product ID: HY-W009236. | |
| Butyrylcholinesterase (BCHE), Horse Serum | Butyrylcholinesterase (BCHE), Horse Serum (BCHE, BuChE, PCHE, pseudocholinesterase, plasma cholinesterase, Acylcholine acyl-hydrolase, Choline esterase, butyryl) is a biological material or organic compound that can be used in life science research[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BCHE, BuChE, PCHE, pseudocholinesterase, plasma cholinesterase, Acylcholine acyl-hydrolase, Choline esterase, butyryl. Pack Sizes: 200 U; 500 U. Product ID: HY-E70362. | |
| Butyryl-Coenzyme A lithium hydrate | Butyryl-Coenzyme A lithium hydrate can synthesize Butyric acid (HY-B0350) or Butyrate [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Butyryl CoA lithium hydrate. CAS No. 1107039-35-9. Pack Sizes: 500 μg; 1 mg. Product ID: HY-141479B. | |
| Butyryl-L-carnitine-d3 chloride | Butyryl-L-carnitine-d 3 (chloride) is the deuterium labeled Butyryl-L-carnitine chloride[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1334532-21-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-115704S1. | |
| Butyzamide | Butyzamide is an orally active activator of Mpl, a thrombopoietin (TPO) receptor. Butyzamide increases the phosphorylation level of JAK2, STAT3, STAT5 and MAPK. Butyzamide increases the level of human platelets in mouse xenotransplantation assay[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1110767-45-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148748. | |
| BV02 | BV02 is a 14-3-3 inhibitor and an antibacterial agent. BV02 enhances the cleavage of PARP and caspase-3. BV02 induces Apoptosis, Autophagy, and enhances Akt activation. BV02 has anti-B. melitensis infection and epilepsy-promoting effects. BV02 can also be used in colitis research. Uses: Scientific research. Group: Signaling pathways. CAS No. 292870-53-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101985. | |
| BV6 | BV6 is an antagonist of cIAP1 and XIAP, members of the inhibitors of apoptosis (IAP) family. Uses: Scientific research. Group: Signaling pathways. CAS No. 1001600-56-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16701. | |
| BVFP | BVFP binds to the PGRN 588 - 593 peptide with a K d of 20 μM. BVFP can disrupt PGRN-SORT1 binding. BVFP also inhibits SORT1-mediated rPGRN endocytosis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 357158-20-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 1100 mg. Product ID: HY-153686. | |
| BVT948 | BVT948 is a protein tyrosine phosphatase (PTP) inhibitor which can also inhibit several cytochrome P450 (P450) isoforms and lysine methyltransferase SETD8 (KMT5A). Uses: Scientific research. Group: Signaling pathways. CAS No. 39674-97-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100625. | |
| BW-723C86 | BW-723C86 is an orally active and a selective 5-HT 2B receptor agonist. BW-723C86 exhibits anxiolytic-like actions. BW-723C86 also causes hyperphagia and reduced grooming in rats. BW-723C86 dilates pulmonary arteries and inhibits liquid meal-induced gastric accommodation [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. CAS No. 160521-72-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101369. | |
| BWA-522 | BWA-522 is an orally available small molecule protein-targeting chimera (PROTACs) with significant degradation effect on AR-FL and AR-V7. BWA-522 antagonizes the N-terminal domain (AR-NTD) of the androgen receptor (Androgen Receptor) and induces apoptosis in PC cells. BWA-522 inhibits tumor growth in LNCaP xenograft model studies (60 mg/kg, po; TGI=76%). The efficiencies of BWA-522 in degrading AR-V7 and AR-FL were 77.3% (1 ?M) and 72.0% (5 ?M) in VCaP and LNCaP cells, respectively[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3042820-12-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-149433. | |
| BX-320 | BX-320 is a selective, ATP-competitive, orally acitive, and direct PDK1 inhibitor with an IC 50 of 30 nM in a direct kinase assay format. BX-320 also induces apoptosis. Anticancer effect [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 702676-93-5. Pack Sizes: 1 mg. Product ID: HY-10515. | |
| BX471 | BX471 (ZK-811752) is an orally active, potent and selective non-peptide CCR1 antagonist with a Ki of 1 nM, and exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZK-811752. CAS No. 217645-70-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-12080. | |
| BX795 | BX795 is a potent and selective inhibitor of PDK1, with an IC50 of 6 nM. BX795 is also a potent and relatively specific inhibitor of TBK1 and IKK?, with an IC50 of 6 and 41 nM, respectively. BX795 blocks phosphorylation of S6K1, Akt, PKC?, and GSK3?, and has lower selectivity over PKA, PKC, c-Kit, GSK3? etc. BX795 modulates autophagy[1][2][3][4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 702675-74-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10514. | |
| BX-912 | BX-912 is a direct, selective, and ATP-competitive PDK1 inhibitor (IC50=26 nM). BX-912 blocks PDK1/Akt signaling in tumor cells and inhibits the anchorage-dependent growth of a variety of tumor cell lines in culture or induces apoptosis[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 702674-56-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-11005. | |
| BYK 191023 dihydrochloride | BYK 191023 is a highly selective inducible nitric-oxide synthase (iNOS) inhibitor. BYK 191023 interacts with the catalytic center of the enzyme. BYK 191023 can be used to study the in vivo and in vitro effects mediated by iNOS [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1216722-25-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-107584. | |
| Bz 423 | Bz 423 is a pro-apoptotic 1,4-benzodiazepine with therapeutic properties in murine models of lupus demonstrating selectivity for autoreactive lymphocytes, and activates Bax and Bak. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BZ48. CAS No. 216691-95-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13108. | |
| BzATP triethylammonium salt | BzATP triethylammonium salt acts as a P2X receptor agonist with pEC50s of 8.74, 5.26, 7.10, 7.50, 6.19, 6.31, 5.33 for P2X1, P2X2, P2X3, P2X2/3, P2X4 and P2X7, respectively[1]. BzATP triethylammonium salt is potent at P2X7 receptors with EC50s of 3.6 ?M and 285 ?M for rat P2X7 and mouse P2X7, respectively[2]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136254. | |
| Bz-FVR-AMC | Bz-FVR-AMC is a fluorogenic substrate for procathepsin with a k cat /K m value of 1070 mM -1 s -1. The high concentration of BZ-FVR-AMC inhibits the substrate [1] [2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 88899-22-3. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-D1634. | |
| Bz-rA | Bz-rA (N6-Benzoyladenosine) is a N6-protected adenosine that can be used to synthesize oligoribonucleotides [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N6-Benzoyladenosine. CAS No. 4546-55-8. Pack Sizes: 10 mM * 1 mL; 25 g; 50 g; 100 g. Product ID: HY-W008388. | |
| Bz-rA Phosphoramidite | Bz-rA Phosphoramidite is used for ribonucleotides modification[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DMT-2'O-TBDMS-rA(bz) Phosphoramidite. CAS No. 104992-55-4. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-W006102. | |
| C004019 | C004019 is a BBB-penetrable and small-molecule PROTAC that targets tau. C004019 can simultaneously recruit tau and E3 ligase, and effectively clear tau proteins by promoting the ubiquitination and proteasome-dependent degradation of tau, thereby improving synaptic and cognitive functions in Alzheimer's disease (AD) mice. C004019 can be used in the research of AD and tau protein-related diseases. (Pink: Ligand for target protein (HY-138679); Black: linker (HY-140189); Blue: E3 Ligase Ligand (HY-138678))[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2417159-57-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138669. | |
| C-021 dihydrochloride | C-021 dihydrochloride is a potent CC chemokine receptor-4 (CCR4) antagonist. C-021 dihydrochloride potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM, respectively. C-021 dihydrochloride effectively prevents human CCL22-derived [35S]GTP?S from binding to the receptor with an IC50 of 18 nM[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1784252-84-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-103364A. | |
| C10 Bisphosphonate | C10 Bisphosphonate is an inhibitor for acid sphingomyelinase. C10 Bisphosphonate is promising for research of inflammatory lung diseases, cystic fibrosis and atherosclerosis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 15049-93-1. Pack Sizes: 1 mg. Product ID: HY-48917. | |
| C12-200 | C12-200 is a type of ionizable cationic lipid and helper lipid commonly used for mRNA delivery. In the hemophilia B mouse model, mRNA encoding human erythropoietin (EPO) and coagulation factor IX (FIX) can be successfully delivered and expressed using C12-200. C12-200 is utilized in research related to hemophilia B [1] [2] [3]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 1220890-25-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145405. | |
| C12-Ceramide | C12-Ceramide (N-Lauroyl-D-erythro-sphingosine), a naturally occurring ceramide, is formed by hydrolysis of C12 sphingomyelin. C12-Ceramide can enhance the Doxorubicin toxicity in MDA-MB-231 cells. C12-Ceramide also can be used to diagnose types A and B Niemann-Pick disease [1] [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N-Lauroyl-D-erythro-sphingosine; N-Laurylsphingosine. CAS No. 74713-60-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-100353. | |
| C12FDG | C12FDG (5-Dodecanoylaminofluorescein di-?-D-Galactopyranoside) is a lipophilic green fluorescent substrate for ?-galactosidase detection. C12-FDG is more sensitive than Fluorescein di(?-D-galactopyranoside) (HY-101895) for beta-galactosidase activity determinations in animal cells (Ex/Em = 488/523 nm)[1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: 5-Dodecanoylaminofluorescein di-?-D-Galactopyranoside. CAS No. 138777-25-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126839. | |
| C12-TLRa | C12-TLRa is an ionized adjuvant lipid. C12-TLRa targets TLR7/8 receptors in endosomes. C12-TLRa enhances mRNA delivery as a structural component of LNPs. C12-TLRa enhances innate immune responses. C12-TLRa can be used for the research of SARS-CoV-2 mRNA vaccine[1][2]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153879. | |
| C14-4 | C14-4 is an ionizable lipid utilized for the synthesis of lipid nanoparticles (LNPs). C14-4 enhances mRNA delivery, enabling the effective transport of mRNA to primary human T cells, which in turn induces functional protein expression. C14-4 demonstrates high transfection efficiency while maintaining low cytotoxicity[1].. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 2639634-80-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-148842. | |
| C14 Ceramide (d18:1/14:0) | C14 Ceramide (d18:1/14:0) is an endogenous ceramide produced by ceramide synthetase 6, which can be used for Parkinson's and diabetes research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 123408-74-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-124177A. | |
| C16-Ceramide | C16-Ceramide is a natural small molecule activating p53 through the direct and selective binding [1]. Uses: Scientific research. Group: Natural products. CAS No. 24696-26-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-100354. | |
| C16 Ceramide-1-phosphate (d18:1/16:0) ammonium | C16 Ceramide-1-phosphate (d18:1/16:0) (ammonium) (C16 Ceramide-1-phosphate (ammonium); Ceramide-1-phosphate (d18:1/16:0) (ammonium)) is an ester product. Uses: Scientific research. Group: Signaling pathways. Alternative Names: C16 Ceramide-1-phosphate ammonium; Ceramide-1-phosphate (d18:1/16:0) ammonium; CerP(d18:1/16:0) ammonium. CAS No. 1246303-22-9. Pack Sizes: 5 mg. Product ID: HY-145467. | |
| C16-PAF | C16-PAF (PAF (C16)), a phospholipid mediator, is a platelet-activating factor and ligand for PAF G-protein-coupled receptor (PAFR). C16-PAF exhibits anti-apoptotic effect and inhibits caspase-dependent death by activating the PAFR. C16-PAF is a potent MAPK and MEK/ERK activator. C16-PAF induces increased vascular permeability[1][2][3][4][5]. Uses: Scientific research. Group: Natural products. Alternative Names: PAF (C16). CAS No. 74389-68-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108635. | |
| C16 PEG2000 Ceramide | C16 PEG2000 Ceramide is a polyethylene glycolylated ceramide. C16 PEG2000 Ceramide can be used for lipid carrier to delivery. C16 PEG2000 Ceramide induces autophagy. C16 PEG2000 Ceramide can be used for cancer research [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: C16 PEG Ceramide (MW 2000). CAS No. 212116-78-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-144005. | |
| C-176 | C-176 is a selective and blood-brain barrier permeable STING inhibitor. C-176 covalently targets transmembrane cysteine residue 91 and thereby blocking activation-induced palmitoylation of STING[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 314054-00-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112906. | |
| C-178 | C-178 is a potent and selective covalent inhibitor of STING. C-178 binds to Cys91 and suppresses the STING responses elicited by distinct bona fide activators in mouse but not human[1].. Uses: Scientific research. Group: Signaling pathways. CAS No. 329198-87-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-123963. | |
| C18:1-Ceramide | C18:1-Ceramide is a ceramide subspecies. C18:1-Ceramide can be used in the study of type 2 diabetes [1]. Uses: Scientific research. Group: Natural products. CAS No. 5966-28-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141578. | |
| C188 | C188 is a STAT3 inhibitor that inhibits IL-6-stimulated STAT3 phosphorylation and nuclear translocation in HepG2 cells by targeting STAT3 SH2 domain peptide-binding pocket. C188, in particular, was highly active in inducing apoptosis of the breast cancer cell line MB-MDA-468 in vitro ( EC 50 = 0.7 μM). Uses: Scientific research. Group: Signaling pathways. Alternative Names: CPD188. CAS No. 823828-18-8. Pack Sizes: 5 mg. Product ID: HY-112338. | |
| C188-9 | C188-9 (TTI-101) is a STAT3 inhibitor, with a K d of 4.7 nM. C188-9 inhibits G-CSF-induced STAT3 activation and STAT3-dependent gene expression. C188-9 induces apoptosis in AML cell lines and primary samples and inhibits colony formation by primary AML blasts [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TTI-101. CAS No. 432001-19-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112288. | |
| C18-Ceramide | C18-Ceramide is a bioactive molecule with multiple functions in cells, can cross the blood-brain barrier, not a traditional agonist or inhibitor targeting a single site. It can act on multiple cellular targets, such as proteins related to endoplasmic reticulum stress (e.g., ATF-4, XBP-1, CHOP), proteins in the PI3K/AKT signaling pathway, and SNARE complex proteins. It exerts activities like inducing cell death, promoting autophagy, and regulating exocytosis through mechanisms such as activating endoplasmic reticulum stress, inhibiting the PI3K/AKT signaling pathway, and affecting lipid raft - related functions. It can be used in research on the mechanism of neuronal injury in the field of neuroscience and in the treatment research of cancers such as glioma in the field of oncology [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 2304-81-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100355. | |
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