MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Bromperidol | Bromperidol (R-11333) possesses antipsychotic activity, with a high affinity for central dopamine receptors D 2. Bromperidol can kill Mycobacteria in a synergistic manner with Spectinomycin [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R-11333. CAS No. 10457-90-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0901. |  |
| Bromperidol hydrochloride | Bromperidol (R-11333) hydrochloride possesses antipsychotic activity, with a high affinity for central dopamine receptors D 2. Bromperidol hydrochloride can kill Mycobacteria in a synergistic manner with Spectinomycin [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R-11333 hydrochloride. CAS No. 59453-24-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0901A. | |
| (-)-Brompheniramine | (-)-Brompheniramine is a H1 receptor antagonist with antiallergic activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R)-Brompheniramine. CAS No. 32656-44-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-402545. | |
| Brompheniramine maleate | Brompheniramine ((±)-Brompheniramine) maleate is a potent and orally active antihistamine of the alkylamine class. Brompheniramine maleate is a selective histamine H1 receptor antagonist with a K d of 6.06 nM. Brompheniramine maleate can block the hERG channels , calcium channels , and sodium channels with IC 50 s of 0.90 μM, 16.12 μM and 21.26 μM, respectively. Brompheniramine maleate has anticholinergic, antidepressant and anesthetic properties and can be used for allergic rhinitis research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)-Brompheniramine maleate. CAS No. 980-71-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B0480. | |
| Bronopol | Bronopol is an antibacterial agent with low toxicity (to mammals) and high activity (especially against Gram-negative bacteria). Uses: Scientific research. Group: Signaling pathways. Alternative Names: BNPD; BNPK. CAS No. 52-51-7. Pack Sizes: 10 mM * 1 mL; 25 g. Product ID: HY-B1217. | |
| Brontictuzumab | Brontictuzumab (OMP 52M51) is a monoclonal antibody (MAb) that inhibits Notch1 signal. Brontictuzumab selectively binds the negative regulatory region of the Notch1. Brontictuzumab inhibits tumor cell proliferation. Brontictuzumab can be used in the research of leukemia and lymphoma [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: OMP 52M51; Anti-Human NOTCH1 Recombinant Antibody. CAS No. 1447814-75-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99258. | |
| Bruceantin | Bruceantin ((-)-Bruceantin) is a quassinoid found in B. javanica. Bruceantin activates caspase signaling pathway, causes the mitochondrial dysfunction, inhibits cell proliferation, induces cell differentiation and apoptosis. Bruceantin exhibits anti-leukemia and antiprotozoal activities[1][2][3]. Uses: Scientific research. Group: Natural products. Alternative Names: (-)-Bruceantin; NCI165563; NSC165563. CAS No. 41451-75-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N0840. | |
| Brusatol | Brusatol (NSC?172924) is a unique inhibitor of the Nrf2 pathway that sensitizes a broad spectrum of cancer cells to Cisplatin and other chemotherapeutic agents. Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism. Brusatol can be developed into an adjuvant chemotherapeutic agent[1]. Brusatol increases cellular apoptosis[2]. Uses: Scientific research. Group: Natural products. Alternative Names: NSC 172924. CAS No. 14907-98-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-19543. | |
| Br-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT | Br-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT (Formula V) is a agent-linker conjugate that composed of a potent topoisomerase I inhibitor and a linker to make an antibody agent conjugate (ADC), ABBV-969[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2857037-70-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-148820. | |
| BS-181 hydrochloride | BS-181 hydrochloride is a highly selective CDK7 inhibitor with IC50 of 21 nM, and > 40-fold selective for CDK7 than CDK1, 2, 4, 5, 6, or 9. Uses: Scientific research. Group: Signaling pathways. CAS No. 1397219-81-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13266A. | |
| BS3 Crosslinker | BS3 Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 82436-77-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124329. | |
| BSB | BSB is a Congo red-derived fluorescent probe. BSB binds not only to extracellular amyloid β protein, but also many intracellular lesions composed of abnormal tau and synuclein proteins. BSB acts as a prototype imaging agent for Alzheimer's disease [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (trans,trans)-1-Bromo-2,5-bis-(3-hydroxycarbonyl-4-hydroxy)styrylbenzene. CAS No. 291766-06-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-D1443. | |
| BSc5367 | BSc5367 is a potent Nek1 inhibitor with an IC50 of 11.5 nM. NIMA-related protein kinase Nek1 is crucially involved in cell cycle regulation, DNA repair and microtubule regulation and dysfunctions of Nek1 play key roles in amyotrophic lateral sclerosis (ALS), polycystic kidney disease (PKD) and several types of radiotherapy resistant cancer[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3029584-84-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144425. | |
| BSJ-03-123 | BSJ-03-123 is a PROTAC connected by ligands for Cereblon and CDK as a potent and novel CDK6-selective small-molecule degrader. Uses: Scientific research. Group: Signaling pathways. CAS No. 2361493-16-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111556. | |
| BSJ-03-204 | BSJ-03-204 is a PROTAC connected by ligands for Cereblon and CDK. BSJ-03-204 is a potent and selective Palbociclib-based CDK4/6 dual degrader (PROTAC), with IC50s of 26.9 nM and 10.4 nM for CDK4/D1 and CDK6/D1, respectively. BSJ-03-204 does not induce IKZF1/3 degradation and has anti-cancer activity[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2349356-09-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136250. | |
| BSJ-04-122 | BSJ-04-122 is a covalent MKK4/7 dual inhibitor. BSJ-04-122 inhibits MKK4 and MKK7 with IC50 values of 4 nM and 181 nM, respectively. BSJ-04-122 can be used for the research of cancer[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2513289-74-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-152185. | |
| BSJ-4-116 | BSJ-4-116 is a PROTAC connected by ligands for Cereblon and CDK. BSJ-4-116 is a highly potent and selective CDK12 degrader (PROTAC) with an IC50 of 6 nM. BSJ-4-116 downregulates DDR genes through a premature termination of transcription, primarily through increasing poly(adenylation). BSJ-4-116 exhibits potent antiproliferative effects, alone and in combination with the poly(ADP-ribose) polymerase inhibitor Olaparib (HY-10162)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2519823-34-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139039. | |
| BT18 | BT18 is a molecule mimic with function similar to glial cell line-derived neurotrophic factor (GDNF) [1]. BT18 shows an effect on GDNF family receptor GFRα1 and RET receptor tyrosine kinase RetA function [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 924811-53-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-111969. | |
| BT2 | BT2 is a BCKDC kinase (BDK) inhibitor with an IC50 of 3.19 ?M. BT2 binding to BDK triggers helix movements in the N-terminal domain, resulting in the dissociation of BDK from the branched-chain ?-ketoacid dehydrogenase complex (BCKDC)[1]. BT2 (compound 4) is also a potent and selective Mcl-1 inhibitor with a Ki value of 59 ?M[2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 34576-94-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-114855. | |
| BT424 | BT424 is a specific HCK inhibitor. BT424 can regulate macrophage activation and autophagy in vitro. BT424 ameliorates inflammation and kidney fibrosis in UUO model [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2755180-37-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-155657. | |
| BT44 | BT44 is a selective RET activator. BT44 can penetrate through the blood-brain barrier and can be used for the research of neurodegenerative disorders and diabetes mellitus [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 924759-42-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153175. | |
| BTB09089 | BTB09089 is a T cell death-associated gene 8 (TDAG8/GPR65) specific agonist. BTB09089 increases TDAG8 expression and regulates the cytokine production of T cells and macrophages[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 245728-44-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149164. | |
| BTB-1 | BTB-1 is a potent, selective and reversible mitotic motor protein Kif18A inhibitor with an IC50 of 1.69 ?M. Uses: Scientific research. Group: Signaling pathways. CAS No. 86030-08-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-101770. | |
| BTD | BTD is a selective transient receptor potential canonical 5 (TRPC5) activator. BTD can be used for the research of neurological disease [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 896684-04-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128205. | |
| BTdCPU | BTdCPU is a potent heme regulated inhibitor kinase (HRI) activator that promotes eIF2? phosphorylation and induces apoptosis in Dexamethasone (HY-14648) (Dex)-resistant cancer cells. BTdCPU can be used in the study of cancers such as multiple myeloma and Dex-resistant multiple myeloma[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1257423-87-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118266. | |
| BTR-1 | BTR-1 is an active anti-cancer agent, causes S phase arrest, and affects DNA replication in leukemic cells. BTR-1 activates apoptosis and induces cell death [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 18331-34-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111617. | |
| BTS | BTS (N-Benzyl-p-toluenesulfonamide) is a potent and selective inhibitor of skeletal muscle myosin II subfragment 1 (S1) ATPase activity, with an IC 50 s of ~5 μM for actin- and Ca 2+ -stimulated myosin S1 ATPase. BTS specifically inhibits the contraction of fast skeletal muscle fibers [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N-Benzyl-p-toluenesulfonamide; N-Tosylbenzylamine. CAS No. 1576-37-0. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-16690. | |
| BTSA1 | BTSA1 is a potent, high affinity and orally active BAX activator with an IC50 of 250 nM and an EC50 of 144 nM. BTSA1 binds with high affinity and specificity to the N-terminal activation site and induces conformational changes to BAX leading to BAX-mediated apoptosis[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 314761-14-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123054. | |
| BTT-3033 | BTT-3033 is an orally active conformation-selective inhibitor of ?2?1 (EC50: 130 nM) by binding to the ?2I domain. BTT-3033 inhibits platelet binding to collagen ? and cell proliferation, and induces cell apoptosis. BTT-3033 can be used in the research of prostate cancer, inflammation and cardiovascular disease[1][2][4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1259028-99-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-110112. | |
| BTTAA | BTTAA is a Cu(I)-stabilizing ligand, whch performs potently with ubiquitin Glu18AzF. Uses: Scientific research. Group: Signaling pathways. CAS No. 1334179-85-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100486. | |
| BTTP | BTTP is a tris(triazolylmethyl)amine-based ligand. BTTP can accelerate the copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC), the prototypical reaction in click chemistry[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1341215-17-5. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W615104. | |
| BTX-A51 | BTX-A51 (Casein Kinase inhibitor A51) is a potent and orally active casein kinase 1α (CK1α) inhibitor. BTX-A51 induces leukemia cell apoptosis , and has potent anti-leukemic activities [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Casein Kinase inhibitor A51. CAS No. 2079068-74-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123954. | |
| BTYNB | BTYNB is a potent and selective inhibitor of IMP1 binding to c-Myc mRNA (IC50=5 ?M). BTYNB exhibits selectivity and effectiveness against IMP1-postive cancer cell lines. BTYNB can be used for cancer research[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 304456-62-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-124447. | |
| BTZO-1 | BTZO-1 binds to Macrophage migration inhibitory factor (MIF) with a K d value of 68.6 nM, and its binding requires the N-terminal Pro1. BTZO-1 can activate antioxidant response element ( ARE )-mediated gene expression and suppress oxidative stress-induced cardiomyocyte apoptosis in vitro [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 99420-15-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110084. | |
| BU224 hydrochloride | BU224 hydrochloride is a selective and high affinity imidazoline I 2 receptor ligand, with a K i of 2.1 nM. BU224 hydrochloride is sometimes used as an I 2 receptor antagonist. BU224 hydrochloride exerts neuroprotective effects, with anti-inflammatory and anti-apoptotic properties. BU224 hydrochloride improves memory in 5XFAD mice, enlarging dendritic spines and reducing Aβ-induced changes in NMDARs. BU224 hydrochloride can be used for Alzheimer's disease research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 205437-64-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-101170. | |
| Bucetin | Bucetin (3-Hydroxy-p-butyrophenetidide) is an antipyretic compound and can also be used in pain relief studies. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 3-Hydroxy-p-butyrophenetidide. CAS No. 1083-57-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-B0906. | |
| Bucillamine | Bucillamine (SA96) is an orally active and potent sulfhydryl donor and antioxidant. Bucillamine is also an antirheumatic agent with antiangiogenic properties. Bucillamine can protect against Ischemia/reperfusion (I/R) injury in high-risk organ transplants. Bucillamine inhibits the production of VEGF. Bucillamine can be used for the research of choroidal neovascularization (CNV) and rheumatoid arthritis (RA) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SA96; Thiobutarit. CAS No. 65002-17-7. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-118530. | |
| Bucindolol | Bucindolol is a β1-adrenergic receptor blocker, with intrinsic sympathomimetic activity, used in the research of heart failure [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 71119-11-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103214. | |
| Bucladesine sodium | Bucladesine sodium salt (Dibutyryl-cAMP sodium salt) is a stabilized cyclic AMP (cAMP) analog and a selective PKA activator. Bucladesine sodium salt raises the intracellular levels of cAMP. Bucladesine sodium salt is also a phosphodiesterase (PDE) inhibitor. Bucladesine sodium salt has anti-inflammatory activity and can be used for impaired wound healing[1][2][3][4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Dibutyryl cAMP sodium salt; DBcAMP sodium salt. CAS No. 16980-89-5. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-B0764. | |
| Buclizine dihydrochloride | Buclizine dihydrochloride is an orally active antihistamine antiallergic compound. Buclizine dihydrochloride is a potent teratogen in the rat and shows anti-tumor activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 129-74-8. Pack Sizes: 100 mg. Product ID: HY-A0128A. | |
| Budesonide | Budesonide, an inhaled glucocortical steroid, is an orally active glucocorticoid receptor agonist. Budesonide decreases the size of lung tumors, reverses DNA hypomethylation and modulates mRNA expression of genes. Budesonide is an anti-inflammatory agent used for asthma [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 51333-22-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-13580. | |
| Budesonide (Standard) | Budesonide (Standard) is the analytical standard of Budesonide. This product is intended for research and analytical applications. Budesonide, an inhaled glucocortical steroid, is an orally active glucocorticoid receptor agonist. Budesonide decreases the size of lung tumors, reverses DNA hypomethylation and modulates mRNA expression of genes. Budesonide is an anti-inflammatory agent used for asthma [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 51333-22-3. Pack Sizes: 10 mg; 25 mg; 50 mg. Product ID: HY-13580R. | |
| Budigalimab | Budigalimab (ABBV 181; PR 1648817) is a humanized, recombinant IgG1 monoclonal antibody targeting programmed cell death 1 ( PD-1 ) receptor. Budigalimab has an Fc mutation that reduces the inhibition of Fc receptor interactions and effector factors. Budigalimab can block the binding of PD-1 and PD-L1, which has anti-tumor activity. Budigalimab can be used in the study of solid tumors [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ABBV 181; PR 1648817. CAS No. 2098225-93-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99489. | |
| Budiodarone tartrate | Budiodarone (ATI-2042) tartrate is a chemical analogue of Amiodarone (HY-14187) with balanced, multiple cardiac ion channel ( potassium , sodium and calcium channels ) inhibiting activity. Budiodarone tartrate is an antiarrhythmic agent [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ATI-2042 tartrate. CAS No. 478941-93-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14834A. | |
| Bufalin | Bufalin is an active component isolated from Chan Su, acts as a potent Na + /K + -ATPase inhibitor, binds to the subunit α1, α2 and α3, with K d of 42.5, 45 and 40 nM, respectively [1] [2]. Anti-cancer activity [2]. Uses: Scientific research. Group: Natural products. CAS No. 465-21-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N0877. | |
| Bufexamac | Bufexamac is a selective ?b HDAC (HDAC6, HDAC10) and LTA4H dual inhibitor, with K d s of 0.53 μM and 0.22 μM for HDAC6 and HDAC10. Bufexamac is a nonsteroida anti-inflammatory drug [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Bufexamic acid. CAS No. 2438-72-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-B0494. | |
| Buflomedil hydrochloride | Buflomedil hydrochloride, a vasodilator agent, is an orally active α1A-adrenoceptor antagonist with K i s of 4.06 μM and 6.84 μM for α1A-AR and α1B-AR, respectively. Buflomedil hydrochloride can be used for the study of peripheral circulatory disorders [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 35543-24-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0484. | |
| Buformin hydrochloride | Buformin hydrochloride (1-Butylbiguanide hydrochloride), a potent AMPK activator, acts as an orally active biguanide antidiabetic agent. Buformin hydrochloride decreases hepatic gluconeogenesis and lowers blood glucose production in vivo. Buformin hydrochloride also has anti-cancer activities and is applied in cancer study (such as, cervical cancer and breast cancer, et al) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 1-Butylbiguanide hydrochloride. CAS No. 1190-53-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg. Product ID: HY-B2099A. | |
| Bufuralol | Bufuralol (Ro 3-4787) is a potent non-selective, orally active β-adrenoreceptor antagonist with partial agonist activity. Bufuralol hydrochloride is a CYP2D6 probe substrate [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro 3-4787. CAS No. 54340-62-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105124. | |
| Bufuralol hydrochloride | Bufuralol (Ro 3-4787) hydrochloride is a potent non-selective, orally active β-adrenoreceptor antagonist with partial agonist activity. Bufuralol hydrochloride is a CYP2D6 probe substrate [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro 3-4787 hydrochloride. CAS No. 60398-91-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105124A. | |
| Bulevirtide | Bulevirtide (Myrcludex B) is a NTCP inhibitor, a linear lipopeptide of 47 amino acids. Bulevirtide inhibits HBV and HDV entry into liver cells, blocks HBV infection in hepatocytes, and participates in HBV transcriptional suppression. Bulevirtide can be used in HDV infection and compensated cirrhosis research [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: Myrcludex B. CAS No. 2012558-47-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P3465. | |
| Bulleyaconitine A | Bulleyaconitine A is an analgesic and antiinflammatory drug isolated from Aconitum plants; has several potential targets, including voltage-gated Na+ channels. Uses: Scientific research. Group: Natural products. CAS No. 107668-79-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0239. | |
| Buloxibutid | Buloxibutid (AT2 receptor agonist C21) is a agentlike selective angiotensin II AT2 receptor agonist with K i values of 0.4 nM and >10 μM for the AT2 receptor and AT1 receptor, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AT2 receptor agonist C21. CAS No. 477775-14-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100113. | |
| Bumetanide | Bumetanide (Ro 10-6338; PF 1593), a highly potent loop diuretic, is a Na + -K + -Cl + cotransporter (NKCC) blocker. Bumetanide is a selective NKCC1 inhibitor, but also inhibits NKCC2, with IC 50 s of 0.68 μM and 4.0 μM for hNKCC1A and hNKCC2A, respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro 10-6338; PF 1593. CAS No. 28395-03-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-17468. | |
| Bunamidine hydrochloride | Bunamidine hydrochloride is a veterinary anti-platyhelmintic agent used for Echinococcus granulosus and Taenia hydatigena [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1055-55-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145079. | |
| Bunazosin | Bunazosin is a potent and selective α1-adrenoceptor antagonist. Bunazosin can be used for antihypertensive and ocular hypotensive research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 80755-51-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-107326. | |
| Buntanetap | Buntanetap ((+)-Phenserine) is a multiple neurotoxic protein translation inhibitor with oral activity, including amyloid precursor protein ( APP ), α-synuclein ( αSYN ) and huntingtin protein ( HTT ). Buntanetap has anti-inflammatory effects and can be used in the study of Alzheimer's disease and Parkinson's disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (+)-Phenserine; ANVS401. CAS No. 116839-68-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16009. | |
| Buntanetap L-Tartrate | Buntanetap (L-Tartrate) is an orally administered small molecule inhibitor of several neurotoxic proteins. Buntanetap reduces amyloid precursor protein (APP) production by blocking its mRNA translation [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (+)-Phenserine L-Tartrate; ANVS401 L-Tartrate. CAS No. 865795-23-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-16009B. | |
| Buparlisib | Buparlisib (BKM120; NVP-BKM120) is a pan-class I PI3K inhibitor, with IC 50 s of 52, 166, 116 and 262 nM for p110α , p110β , p110δ and p110γ , respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BKM120; NVP-BKM120. CAS No. 944396-07-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-70063. | |
| Buparlisib Hydrochloride | Buparlisib Hydrochloride (BKM120 Hydrochloride) is a pan-class I PI3K inhibitor, with IC 50 of 52 nM/166 nM/116 nM/262 nM for p110α / p110β / p110δ / p110γ , respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BKM120 Hydrochloride; NVP-BKM120 Hydrochloride. CAS No. 1312445-63-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15180. | |
| Buparvaquone | Buparvaquone is a hydroxynaphthoquinone antiprotozoal agent related to parvaquone and atovaquone. Uses: Scientific research. Group: Signaling pathways. CAS No. 88426-33-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17581. | |
| Bupirimate | Bupirimate possesses antifungal activity. Bupirimate is compatible with most of fungicides, insecticides and adjuvants, with very limited exceptions on some crops [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 41483-43-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133216. | |
| Bupivacaine | Bupivacaine is a NMDA receptor inhibitor. Bupivacaine can block sodium , L-calcium , and potassium channels.Bupivacaine potently blocks SCN5A channels with the IC 50 of 69.5 μM. Bupivacaine can be used for the research of chronic pain [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 38396-39-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0405. | |
| Bupivacaine hydrochloride | Bupivacaine hydrochloride is a NMDA receptor inhibitor.Bupivacaine can block sodium , L-calcium , and potassium channels.Bupivacaine potently blocks SCN5A channels with the IC 50 of 69.5 μM. Bupivacaine hydrochloride can be used for the research of chronic pain [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 18010-40-7. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0405A. | |
| Bupivacaine (hydrochloride) (Standard) | Bupivacaine (hydrochloride) (Standard) is the analytical standard of Bupivacaine (hydrochloride). This product is intended for research and analytical applications. Bupivacaine hydrochloride is a NMDA receptor inhibitor.Bupivacaine can block sodium , L-calcium , and potassium channels.Bupivacaine potently blocks SCN5A channels with the IC 50 of 69.5 μM. Bupivacaine hydrochloride can be used for the research of chronic pain [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 18010-40-7. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0405AR. | |
| Bupranolol | Bupranolol is an orally active, competitive and non-selective β-adrenoceptor antagonist without intrinsic sympathomimetic activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 14556-46-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-A0252. | |
| Buprofezin | Buprofezin is a broad-spectrum insecticide and chitin synthesis inhibitor that targets developmental stage coleopteran pests.Buprofezin promotes the conversion of energy metabolism from the aerobic tricarboxylic acid (TCA) cycle and oxidative phosphorylation to anaerobic glycolysis. Buprofezin also promotes the production of reactive oxygen species (ROS) by inhibiting cytochrome c oxidase [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 69327-76-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B0831. | |
| BUR1 | BUR1 is a BMP upregulator (EC 50 : 98 nM) and activates BMPRII signalling. BUR1 induces BMP2 and PTGS2 expression. BUR1 reversed pulmonary arterial pressure in Monocrotaline (HY-N0750) induced rats [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 23000-46-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-121025. | |
| Burgess reagent | Burgess reagent is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 29684-56-8. Pack Sizes: 10 g; 25 g. Product ID: HY-W040081. | |
| Burosumab | Burosumab is a human fibroblast growth factor 23 (FGF23) neutralizing antibody that can be used for the research of X-linked hypophosphatemia (XLH) and tumor-induced osteomalacia [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: KRN23. CAS No. 1610833-03-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9939. | |
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