BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Awamycin | Awamycin is produced by the strain of Streptomyces sp. No. 80-217. It has anti-gram-positive bacteria and antitumor activity. Synonyms: Antibiotic Tan 528A; Protostreptovaricin I, 10,25-didemethyl-21-hydroxy-10-(methoxycarbonyl)-19-O-methyl-25-(methylthio)-; Protostreptovaricin-31-oic acid, 25-demethyl-21-hydroxy-19-O-methyl-2S-(methylthio)-, methyl ester. Molecular formula: C38H49NO12S. Mole weight: 743.86. |  |
| Axenomycin B | Axenomycin B is produced by the strain of Streptomyces lisandri F. I. 2604. It has antifungal, nematode and trichomonas activities. Molecular formula: C29H38O10. Mole weight: 546.60. | |
| Axinysone B | Axinysone B is a metabolite of the mushroom Anthracophyllum sp. BCC18695. Synonyms: (-)-Axinysone B; 2H-Cyclopropa[a]naphthalen-2-one, 1,1a,4,5,6,7,7a,7b-octahydro-4-hydroxy-1,1,7,7a-tetramethyl-, (1aS,4R,7S,7aS,7bR)-. Grade: 98.0%. CAS No. 1114491-60-9. Molecular formula: C15H22O2. Mole weight: 234.33. | |
| Azepinomycin | Azepinomycin is produced by the strain of Streptomyces toyokaensis MF71803. It can inhibit Guanase and tumor cell. Synonyms: 4,5,6,7-Tetrahydro-6-hydroxy-3H-imidazo-(4,5e)(1,4)diazepin-8-one; 3,4,5,6-Tetrahydroimidazo[4,5-e][1,4]diazepine-6,8-diol. CAS No. 89354-15-4. Molecular formula: C6H8N4O2. Mole weight: 168.15. | |
| Azetomycin I | Azetomycin I is produced by the strain of Streptomyces antibioticus 3820. It has the effect of anti-gram positive bacteria, the activity of I and II against Bacillus subtilis was equal to 80% and 70% of that of actinomycin ?. Synonyms: Azetomicin I; Actinomycin D, 3(sup A)(or 3-(sup B))-(2-azetidinecarboxylic acid)-. CAS No. 59519-94-7. Molecular formula: C61H84N12O16. Mole weight: 1241.39. | |
| Azetomycin II | Azetomycin II is produced by the strain of Streptomyces antibioticus 3820. It has the effect of anti-gram positive bacteria, the activity of I and II against Bacillus subtilis was equal to 80% and 70% of that of actinomycin ?. Synonyms: Azetomicin II; 3A-(2-Azetidinecarboxylic acid)-3B-(2-azetidinecarboxylic acid)actonomycin D; 3'-Azetidine-3'-azetidine-actinomycin. CAS No. 59481-55-9. Molecular formula: C60H82N12O16. Mole weight: 1227.36. | |
| Azicemicin A | Azicemicin A is produced by the strain of Amycolatopsis sulphurea (MJ126-NF4). The antibacterial activity of A was weak, and the mice were given 150mg/kg intraperitoneally without any acute toxicity. Synonyms: Benz(a)anthracene-1,6(2H,5H)-dione, 3,4,4a,12b-tetrahydro-9,12-dimethoxy-3-(1-methyl-2-aziridinyl)-3,7,8,10,12b-pentahydroxy-. CAS No. 154163-93-6. Molecular formula: C23H25NO9. Mole weight: 459.44. | |
| Azicemicin B | Azicemicin B is produced by the strain of Amycolatopsis sulphurea (MJ126-NF4). B showed a weak gram-positive bacterial activity and had some effect on Mycobacterium (MIC 6.25-25μg/mL). Synonyms: Benz(a)anthracene-1,6(2H,5H)-dione, 3,4,4a,12b-tetrahydro-3-(2-aziridinyl)-9,12-dimethoxy-3,7,8,10,12b-pentahydroxy-. CAS No. 162857-75-2. Molecular formula: C22H23NO9. Mole weight: 445.42. | |
| Azidocillin | Azidocillin is produced by the strain of 6-APA and Ampicillin. The activity of anti-hemolytic Streptococcus, Streptococcus pneumoniae and enterococcus is slightly better than penicillin, while staphylococcus aureus, which is sensitive to penicillin, is slightly better than penicillin, and is less stable to penicillinase than amamicillin to influenza bacilli. Stable to acid, oral. The preparation is its sodium salt or potassium salt (melting point 194°C decomposition), used as an antibacterial agent and feed additive. Synonyms: AZIDOCILLIN; GLOBACILLIN; 6α-(2-Azido-2-phenylacetylamino)penicillanic acid; BRL 2534; SPC 297 D. Grade: 95%. CAS No. 17243-38-8. Molecular formula: C16H17N5O4S. Mole weight: 375.41. | |
| Azinomycin A | Azinomycin A is produced by the strain of Streptomyces griseofuscus. It was highly cytotoxic, and the cytotoxicity of A and B to L5178Y cell IC50 was 0.07 g/mL and 0.11 g/mL, respectively. Synonyms: 1-Naphthalenecarboxylic acid, 3-methoxy-5-methyl-, 2-((1-(3-(acetyloxy)-4-hydroxy-1-azabicyclo(3.1.0)hex-2-ylidene)-2-oxo-2-((2-oxopropyl)amino)ethyl)amino)-1-(2-methyloxiranyl)-2-oxoethyl ester. CAS No. 106486-77-5. Molecular formula: C30H33N3O10. Mole weight: 595.60. | |
| Azinomycin B | Azinomycin B is produced by the strain of Streptomyces griseofuscus. It was highly cytotoxic, and the cytotoxicity of A and B to L5178Y cell IC50 was 0.07 g/mL and 0.11 g/mL, respectively. Synonyms: CARZINOPHILIN A; Cardinophyllin. Molecular formula: C31H33N3O11. Mole weight: 623.61. | |
| Azinothricin | Azinothricin is produced by the strain of Streþtomyces sp. X-14950. It has strong anti-gram-positive bacteria and anaerobic bacteria activity, and the resistance of gram-negative bacteria and fungi showed weak activity. Synonyms: 2H-Pyran-2-acetamide, alpha-ethyl-6-(3-ethyl-1,5-dimethyl-4-oxo-1,5-heptadienyl)-N-(1,8,14,15,18,21,27-heptaaza-21-hydroxy-7-(1-hydroxyethyl)-2,6,9,16,19,22-hexaoxo-4-isopropyl-20-(methoxymethyl)-17,18-dimethyl-5-oxatricyclo(21.4.0.0(sup 10,15))heptacosan-3-yl)tetrahydro-alpha-2-dihydroxy-5-methyl-. CAS No. 101342-90-9. Molecular formula: C49H80N8O15. Mole weight: 1021.20. | |
| Azirinomycin | Azirinomycin is produced by the strain of Streptomyces aureus. It has anti-gram positive and negative bacterial activity. Synonyms: 3-Methyl-2H-azirine-2-carboxylic acid; 2H-AZIRINE-2-CARBOXYLIC ACID, 3-METHYL-. CAS No. 31772-89-1. Molecular formula: C4H5NO2. Mole weight: 99.09. | |
| Azlocillin | Azlocillin is produced by the strain of 6-APA and Ampicillin. It has a wide antibacterial spectrum, and has good effects on gram-positive cocci (except penicillin-resistant Staphylococcus aureus), negative bacilli including Pseudomonas aerumindole-negative proteus, etc. The experimental efficacy is better than Carbencillin and Ticarcillin, and it is widely applied in clinical practice. Synonyms: AZLOCILLIN ACID; 3,3-Dimethyl-6-oxo-7-[2-(2-oxoimidazolidin-1-yl)carbonylamino-2-phenyl-acetyl]amino-2-thia-5-azabicyclo[3.2.0]heptane-4-carboxylic acid; 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,3,3-dimethyl-7-oxo-6-[[[[(2-oxo-1-imidazolidinyl)carbonyl]amino]phenylacetyl]amino]-, [2S-[2a,5a,6b(S*)]]-. Grade: 95%. CAS No. 37091-66-0. Molecular formula: C20H23N5O6S. Mole weight: 461.49. | |
| Azotochelin | Azotochelin is produced by the strain of Azotobacter vinelandii. Synonyms: N2,N6-Bis(2,3-dihydroxybenzoyl)-L-lysine; L-Lysine, N2,N6-bis(2,3-dihydroxybenzoyl). CAS No. 23369-85-9. Molecular formula: C20H22N2O8. Mole weight: 418.40. | |
| Azoxybacilin | Azoxybacilin is produced by the strain of Bacillus cereus NR2991. It can inhibit the sulfur fixation reaction in methionine biosynthesis and has strong anti-filamentous fungal activity: The IC80 of Aspergillus fumigata and Trichoderma was 0.71 ~ 1.3 μg/mL and 0.03 ~ 0.24 μg/mL, respectively. It had only moderate activity to yeast-based fungi, and the IC80 of Candida albicans was 4.2 ~ 5.8 μg/mL. Synonyms: (2s)-2-amino-4-[(z)-methyl-nno-azoxy]butanoic acid; Butanoic acid, 2-amino-4-[(1Z)-methyl-NNO-azoxy]-, (2S)-. CAS No. 157998-96-4. Molecular formula: C5H11N3O3. Mole weight: 161.16. | |
| B-5354a | B-5354a is a Sphingosine kinase (SPHK) inhibitor produced by SANK 71896. It has the activity of inhibiting SPHK with IC50 of 21 μmol/L. Molecular formula: C19H29NO3. Mole weight: 319.44. | |
| B-5354b | B-5354b is a Sphingosine kinase (SPHK) inhibitor produced by SANK 71896. It has the activity of inhibiting SPHK with IC50 of 58 μmol/L. Molecular formula: C21H31NO3. Mole weight: 345.47. | |
| B-5354c | B-5354c is a Sphingosine kinase (SPHK) inhibitor produced by SANK 71896. It has the activity of inhibiting SPHK with IC50 of 38 μmol/L. Molecular formula: C21H33NO3. Mole weight: 347.49. | |
| B-90063 | B-90063 is an endothelin transferase (ECE) inhibitor produced by Blastobacter sp. SANK 71894. It has a strong inhibitory effect on human and rat ECE, with IC50 of 1.0 and 3.2 μmol/L, respectively. Molecular formula: C28H30N4O6S2. Mole weight: 582.69. | |
| Bacilysin | Bacilysin is produced by the strain of Bacillus subtilis A-14. It has gram-positive bacterial activity against Staphylococcus aureus and Dryness bacillus. Culture is enriched with bacillus subtilis (Bacilip in). Synonyms: Tetaine; Antibiotic KM 208; N-L-Alanyl-3-(5-oxo-7-oxabicyclo(4.1.0)hept-2-yl)-L-alanine. CAS No. 29393-20-2. Molecular formula: C12H18N2O5. Mole weight: 270.28. | |
| Baciphelacin | Baciphelacin is produced by the strain of Bacillus thiaminolyticus. It is mainly resistant to gram-positive bacteria and has the activity of inhibiting Newcastle disease virus and leukemia P-388 cells. Synonyms: baciphelacin; Antibiotic B 17; 5-Amino-N-[1-(3,4-dihydro-8-hydroxy-1-oxo-1H-2-benzopyran-3-yl)-3-methylbutyl]-2-methyl-3,4-dihydroxyheptanamide. CAS No. 57765-71-6. Molecular formula: C22H34N2O6. Mole weight: 422.52. | |
| Bacithrocin A | Bacithrocin A is produced by the strain of Bacillus laterosporus Laubach NR 2988. The ED50 of the four components A, B, C and D were 48, 84, 80, 124X10-6 mol/L, and the reference antipain was 13X10-6 mol/L, respectively. Molecular formula: C20H31N5O3. Mole weight: 389.49. | |
| Bacithrocin B | Bacithrocin B is produced by the strain of Bacillus laterosporus Laubach NR 2988. The ED50 of the four components A, B, C and D were 48, 84, 80, 124X10-6 mol/L, and the reference antipain was 13X10-6 mol/L, respectively. Molecular formula: C19H29N5O3. Mole weight: 375.46. | |
| Bacithrocin C | Bacithrocin C is produced by the strain of Bacillus laterosporus Laubach NR 2988. The ED50 of the four components A, B, C and D were 48, 84, 80, 124X10-6 mol/L, and the reference antipain was 13X10-6 mol/L, respectively. Molecular formula: C18H27N5O3. Mole weight: 361.44. | |
| Bacithrocin D | Bacithrocin D is produced by the strain of Bacillus laterosporus Laubach NR 2988. The ED50 of the four components A, B, C and D were 48, 84, 80, 124X10-6 mol/L, and the reference antipain was 13X10-6 mol/L, respectively. Synonyms: SCHEMBL21360283. CAS No. 96440-64-1. Molecular formula: C17H25N5O3. Mole weight: 347.41. | |
| Bacitracin F, copper deriv. | Bacitracin is a cyclic peptide complex isolated from Bacillus licheniformis. Bacitracin has anti-Gram-positive bacteria activity and can be used clinically as a topical treatment for skin infections. Grade: >95% by HPLC. CAS No. 85800-09-5. Molecular formula: C66H101CuN17O16S. Mole weight: 1484.23. | |
| Bacteriochlorophylls a | Bacteriochlorophylls a is produced by the strain of Chlorobiea and Rhodospirillinea. It has a structural skeleton similar to chlorophyll of higher plants. Synonyms: Bacteriochlorophyll; C11242. Grade: ≥95%. CAS No. 17499-98-8. Molecular formula: C55H74MgN4O6. Mole weight: 911.50. | |
| Bacteriochlorophylls b | Bacteriochlorophylls b is produced by the strain of Chlorobiea and Rhodospirillinea. It has a structural skeleton similar to chlorophyll of higher plants. Molecular formula: C55H72MgN4O6. Mole weight: 909.49. | |
| Badione A | It is produced by the strain of Xerocomus badius. Badione A can form a stable salt with potassium ions. Molecular formula: C36H18O17. Mole weight: 722.52. | |
| Badione B | It is produced by the strain of Xerocomus badius. Badione B can form a stable salt with potassium ions. Molecular formula: C36H18O18. Mole weight: 738.52. | |
| Bafilomycin | Bafilomycins are a family of macrolide antibiotics isolated from Streptomycetes sp. They exhibits antitumor, antiparasitic, immunosuppressant and antifungal activity. CAS No. 151499-39-7. | |
| Bafilomycin C1 | Bafilomycin C1 is a macrolide compound found in Streptomyces and an inhibitor of V-ATPase protein. It has a wide range of activities against bacteria, fungi, insects, and nematodes. It is a potential drug for the treatment of osteoporosis. Synonyms: L-681,110A1. Grade: >95% by HPLC. CAS No. 88979-61-7. Molecular formula: C39H60O12. Mole weight: 720.88. | |
| Bagougeramine A | Bagougeramine A is produced by the strain of Bacillus circulans TB-2125. Both of A and B have activities against gram-positive bacteria and negative bacteria, and B has higher activity than A, except for Pseudomonas aeruginosa A3. Synonyms: beta-D-Glucopyranuronamide, 4-((3-((aminoiminomethyl)amino)-N-(N-methylglycyl)-D-alanyl)amino)-1-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,4-dideoxy-. CAS No. 104840-35-9. Molecular formula: C17H28N10O7. Mole weight: 484.47. | |
| Bagougeramine B | Bagougeramine B is produced by the strain of Bacillus circulans TB-2125. Both of A and B have activities against gram-positive bacteria and negative bacteria, and B has higher activity than A, except for Pseudomonas aeruginosa A3. Synonyms: beta-D-Glucopyranuronamide, N-(3-((4-aminobutyl)amino)propyl)-4-((3-((aminoiminomethyl)amino)-N-(N-methylglycyl)-D-alanyl)amino)-1-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,4-dideoxy-. CAS No. 104840-34-8. Molecular formula: C24H44N12O7. Mole weight: 612.68. | |
| Bagremycin A | It is produced by the strain of Streptomyces sp. Tu 4128. Bagremycin A has weak activity against gram-positive bacteria, Saccharomyces cerevisiae and Candida albicans. Synonyms: CHEMBL4125959. Molecular formula: C15H13NO3. Mole weight: 255.27. | |
| Bagremycin B | It is produced by the strain of Streptomyces sp. Tu 4128. Bagremycin B has weaker activity against gram-positive bacteria, Saccharomyces cerevisiae and Candida albicans than A. Synonyms: CHEMBL4129272. Molecular formula: C17H15NO4. Mole weight: 297.30. | |
| Balhimycin | It is produced by the strain of Amycolatopsis sp. 8621022. Balhimycin has the activity of congela-positive bacteria (including MRSA) similar to vancomycin. Synonyms: DB04111; balhimycin. CAS No. 140932-79-2. Molecular formula: C66H73Cl2N9O24. Mole weight: 1447.23. | |
| Bamicetin | Bamicetin is produced by the strain of Streptomyces licatus. Mainly resistant to gram-positive bacteria and Mycobacteria, acute toxicity is lower than Amicetin (dog, subcutaneous). Synonyms: Benzamide, 4-((2-amino-3-hydroxy-2-methyl-1-oxopropyl)amino)-N-(1,2-dihydro-2-oxo-1-(2,3,6-trideoxy-4-O-(4,6-dideoxy-4-(methylamino)-alpha-D-glucopyranosyl)-beta-D-erythro-hexopyranosyl)-4-pyrimidinyl)-, (S)-. CAS No. 43043-14-7. Molecular formula: C28H40N6O9. Mole weight: 604.65. | |
| Barbamide | Barbamide is produced by the strain of Lyn-gbya majiuscula. It has the activity of killing mollusks. Synonyms: CHEBI:80028. Molecular formula: C20H23Cl3N2O2S. Mole weight: 461.83. | |
| Barbatic acid | Barbatic acid is a substance obtained from Cladia aggregata (lichen), which exhibits schistosomiasis effect on adult Schistosoma mansoni. CAS No. 17636-16-7. Molecular formula: C19H20O7. Mole weight: 360.36. | |
| Barminomycin I | Barminomycin I is produced by the strain of Actinomadura roseoviolacea and A. carminata. I and II showed strong inhibition of P388 leukemia cells with IC50 of about 0.00001 and 0.00002 g/mL, respectively (reference Doxorubicin of 0.013 g/mL). Synonyms: SN-07 Chromophore; 5,12-Naphthacenedione,8-acetyl-10-[[4,6a,7,8,10,10a-hexahydro-2-(2-hydroxypropyl)-4,10-dimethylpyrano[3,4-d]-1,3,6-dioxazocin-8-yl]oxy]-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-(9CI). CAS No. 108147-17-7. Molecular formula: C33H37NO12. Mole weight: 639.64. | |
| Barminomycin II | Barminomycin II is produced by the strain of Actinomadura roseoviolacea and A. carminata. I and II showed strong inhibition of P388 leukemia cells with IC50 of about 0.00001 and 0.00002 g/mL, respectively (reference Doxorubicin of 0.013 g/mL). Synonyms: 8-Acetyl-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-10-((octahydro-5-hydroxy-2-(2-hydroxypropyl)-4,10-dimethylpyrano(3,4-d)-1,3,6-dioxazocin-8-yl)oxy)-5,12-naphthacenedione; 5,12-Naphthacenedione, 8-acetyl-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-10-((octahydro-5-hydroxy-2-(2-hydroxypropyl)-4,10-dimethylpyrano(3,4-d)-1,3,6-dioxazocin-8-yl)oxy)-. CAS No. 108089-33-4. Molecular formula: C33H39NO13. Mole weight: 657.66. | |
| Basidalin | Basidalin is produced by the strain of Leucoagaricus naucina NZ157. It has the ability of anti-gram-positive bacteria, negative bacteria and inhibition of mouse leukemia L-1210 cell. Synonyms: (Z)-4-Amino-5-(formylmethylene)-2(5H)-furanone; (Z)-(3-Amino-5-oxo-2(5H)-furanylidene)acetaldehyde; Acetaldehyde, (3-amino-5-oxo-2(5H)-furanylidene)-. Molecular formula: C6H5NO3. Mole weight: 139.11. | |
| Bassianin | Bassianin is a fungal metabolite isolated from Beauveria bassiana. Bassianin is cytotoxic to Sf9 and Sf21 insect cells with 50% cytotoxic concentration (CC50) values of 4.91 and 12.12 μM, respectively. Grade: >95% by HPLC. CAS No. 54278-73-8. Molecular formula: C23H25NO5. Mole weight: 395.45. | |
| Baumycin A1 | Baumycin A1 is produced by the strain of Streptomyces sp. ME 130-A4. Synonyms: 5,12-Naphthacenedione, 8-acetyl-10-((3-amino-2,3,6-trideoxy-4-O-(3-hydroxy-1-(2-hydroxy-1-methylethoxy)butyl)-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, (8S-cis)-. CAS No. 64314-28-9. Molecular formula: C34H43NO13. Mole weight: 673.70. | |
| Baumycin B1 | Baumycin B1 is produced by the strain of Streptomyces sp. ME 130-A4. Synonyms: 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-8-acetyl-10-((3-amino-4-O-(1-(1-carboxyethoxy)-3-hydroxybutyl)-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-6,8,11-trihydroxy-1-methoxy-, (8S-cis)-; 3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-4-o-[1-(1-carboxyethoxy)-3-hydroxybutyl]-2,3,6-trideoxyhexopyranoside. CAS No. 64253-72-1. Molecular formula: C34H41NO14. Mole weight: 687.69. | |
| BE-10988 | BE-10988 is a topoisomerase-II inhibitor produced by Str. sp. BA 10988. It has the activity of inhibiting P388 murine leukemia cells. It inhibits P388 (P388S), vincristine-doxorubicin-resistant P388 (P388/VCR) and doxorubicin-resistant P388 (P388/MDR) cells with IC50 (μmol/L) of 0.5, 0.4, 2.0, respectively. CAS No. 135261-89-1. Molecular formula: C13H10N4O3S. Mole weight: 302.31. | |
| BE-12406 A | BE-12406 A is an antitumor antibiotic produced by Streptomyces rutrersensis subsp. castelarensis. It has the activity of inhibiting murine P388 leukemia cells (IC50 is 0.8 μmol/L), and has the same activity against vincristine-doxorubicin resistant strains (P388/VCR) (IC50 is 0.2 μmol/L). It can inhibit the growth of S480 ascites carcinoma in mice. Synonyms: BE 12406A; 6H-Benzo(d)naphtho(1,2-b)pyran-6-one, 12-((6-deoxy-alpha-L-mannopyranosyl)oxy)-1-hydroxy-10-methoxy-8-methyl-. CAS No. 132417-96-0. Molecular formula: C25H24O9. Mole weight: 468.45. | |
| BE-12406 B | BE-12406 B is an antitumor antibiotic produced by Streptomyces rutrersensis subsp. castelarensis. It has the activity of inhibiting murine P388 leukemia cells (IC50 is 7 μmol/L), and has the same activity against vincristine-doxorubicin resistant strains (P388/VCR) (IC50 is 7 μmol/L). It can inhibit the growth of S480 ascites carcinoma in mice. Synonyms: 12-((6-Deoxyhexopyranosyl)oxy)-1,10-dihydroxy-8-methyl-6H-benzo(d)naphtho(1,2-b)pyran-6-one. CAS No. 132417-97-1. Molecular formula: C24H22O9. Mole weight: 454.43. | |
| BE-18257A | BE-18257 A is an endothelin binding inhibitor produced by Streptomyces misakiensis. Synonyms: Cyclo(valyl-leucyl-tryptophyl-glutamyl-alanyl); Cyclo(L-alanyl-D-valyl-L-leucyl-D-tryptophyl-D-alpha-glutamyl). CAS No. 136553-73-6. Molecular formula: C30H42N6O7. Mole weight: 598.69. | |
| BE-18257B | BE-18257 B is an endothelin binding inhibitor produced by Streptomyces misakiensis. Synonyms: Cyclo(L-alanyl-D-alloisoleucyl-L-leucyl-D-tryptophyl-D-alpha-glutamyl); LS-55815. Molecular formula: C31H44N6O7. Mole weight: 612.72. | |
| BE-19412A | BE-19412A is an antitumor antibiotic extracted from the culture medium of Streptomyces sp. A19412. It is toxic to mouse and human tumor cells such as P388, Ehrlich, DLD-1, PC-13, MKN-45 and Colon 26, with IC50 of 0.9-5.4 μg/mL, and can prolong the survival time of CDF1 mice with Ehrlich cancer. Synonyms: LS-94141. CAS No. 173774-90-8. Molecular formula: C28H22ClNO8. Mole weight: 535.93. | |
| BE-19412B | BE-19412B is an antitumor antibiotic extracted from the culture medium of Streptomyces sp. A19412. It is toxic to mouse and human tumor cells such as P388, Ehrlich, DLD-1, PC-13, MKN-45 and Colon 26, with IC50 of 0.9-5.4 μg/mL, and can prolong the survival time of CDF1 mice with Ehrlich cancer. Synonyms: LS-94140. CAS No. 173774-91-9. Molecular formula: C30H26ClNO8. Mole weight: 563.98. | |
| BE-23372M | BE-23372M is a protein tyrosine kinase inhibitor produced by Rhizoctonia solani. It has strong inhibition of epidermal growth factor (EGF) receptor kinase activity. Synonyms: (3E)-3-(3,4-dihydroxybenzylidene)-5-(3,4-dihydroxyphenyl)furan-2(3H)-one. CAS No. 145588-13-2. Molecular formula: C17H12O6. Mole weight: 312.27. | |
| BE-29602 | BE-29602 is a papulacandin antibiotic produced by Fusarium sp. F296O2. It has activity against Candida, Saccharomyces cerevisiae and other fungi, with an MIC of 0.20-0.7 μg/mL. It is cytotoxic and has an IC50 of 21 μg/mL to P388 murine leukemia cells. Molecular formula: C45H62O16. Mole weight: 858.96. | |
| BE-31405 | BE-31405 is an antifungal antibiotic produced by Penicillum minioluteum F31405. It has activity against pathogenic fungi such as Candida albicans and Cryptococcus neoformans (MIC 3.13-6.25 μg/mL), and has no cytotoxicity to mammalian cells (such as P388 murine leukemia, etc.). Molecular formula: C28H36O10. Mole weight: 532.58. | |
| BE-32030A | BE-32030A is an antitumor antibiotic produced by Nocardia sp. A32030. It has inhibitory effect on the growth of P388, DLD-h PC-13 and MKN-45 tumor cells. Synonyms: BE-32030 A. CAS No. 161589-09-9. Molecular formula: C39H61N5O10. Mole weight: 759.93. | |
| BE-32030B | BE-32030B is an antitumor antibiotic produced by Nocardia sp. A32030. It has inhibitory effect on the growth of P388, DLD-h PC-13 and MKN-45 tumor cells. Synonyms: Lysine, N(sup 2)-((4,5-dihydro-2-(2-hydroxyphenyl)-4-methyl-4-oxazolyl)carbonyl)-N(sup 6)-hydroxy-N(sup 6)-(1-oxotetradecyl)-, 3-((hexahydro-1-hydroxy-2-oxo-1H-azepin-3-yl)amino)-1-methyl-3-oxopropyl ester; BE-32030 B. CAS No. 161589-10-2. Molecular formula: C41H65N5O10. Mole weight: 787.98. | |
| BE-32030C | BE-32030C is an antitumor antibiotic produced by Nocardia sp. A32030. It has inhibitory effect on the growth of P388, DLD-h PC-13 and MKN-45 tumor cells. Synonyms: BE-32030 C. CAS No. 161589-11-3. Molecular formula: C43H67N5O10. Mole weight: 814.02. | |
| BE-32030D | BE-32030D is an antitumor antibiotic produced by Nocardia sp. A32030. It has inhibitory effect on the growth of P388, DLD-h PC-13 and MKN-45 tumor cells. Synonyms: BE-32030 D. CAS No. 161589-12-4. Molecular formula: C39H61N5O11. Mole weight: 775.93. | |
| BE-32030E | BE-32030E is an antitumor antibiotic produced by Nocardia sp. A32030. It has inhibitory effect on the growth of P388, DLD-h PC-13 and MKN-45 tumor cells. Synonyms: BE-32030 E. CAS No. 161589-13-5. Molecular formula: C41H63N5O10. Mole weight: 785.97. | |
| BE-40644 | BE-40644 is an inhibitor of human Thioredoxin system produced by Actinoplanes sp. A40644. It can inhibit the growth of several tumor cells. Synonyms: 4,4,6aalpha,12bbeta-Tetramethyl-9-(hydroxymethyl)-1,3,4,4aalpha,5,6,6a,12,12aalpha,12b-decahydro-2H-benzo[a]xanthene-8,11-dione. CAS No. 172923-88-5. Molecular formula: C22H30O4. Mole weight: 358.47. | |
| BE-40665D | BE-40665D is an antibiotic produced by Actinoplanes sp. A4O665. It has moderate anti-gram-positive bacteria activity and has no effect on gram-positive bacteria. CAS No. 183241-67-0. Molecular formula: C22H21BrO7. Mole weight: 477.30. | |
| BE-43472B | BE-43472B is a bisanthraquinone antibiotic isolated from a streptomycete strain. It has antibacterial activity against MSSA, MRSA, TRSA and VRE. Synonyms: (8S,9S,9aR,18aS,20R)-8,9-Dihydro-4,6,8,16-tetrahydroxy-8,14,20-trimethyl-18a,9-(epoxymethano)-18aH-dianthra[1,2-b:4'a,10'-d]furan-5,12,17(7H)-trione; 18a,9-(Epoxymethano)-18aH-dianthra[1,2-b:4'a,10'-d]furan-5,12,17(7H)-trione, 8,9-dihydro-4,6,8,16-tetrahydroxy-8,14,20-trimethyl-, (8S,9S,9aR,18aS,20R)-. CAS No. 180027-59-2. Molecular formula: C32H24O9. Mole weight: 552.53. | |
| BE-52440A | BE-52400A is a cytotoxicity produced by Streptomyces sp. A52400. It has anti-proliferative effect on mouse tumor cell lines such as P388 leukemia and colon 26 colon and human tumor cell lines such as DLD1 (colon), PC-13 (lung), MKN-45 (stomach), etc., with IC50 of 6.1, 2.1, 0.47, 3.9, 0.88 μg/mL. CAS No. 195051-22-0. Molecular formula: C34H34O14S. Mole weight: 698.69. | |
| BE-52440B | BE-52400B is a cytotoxicity produced by Streptomyces sp. A52400. It has anti-proliferative effect on mouse tumor cell lines such as P388 leukemia and colon 26 colon and human tumor cell lines such as DLD1 (colon), PC-13 (lung), MKN-45 (stomach), etc., with IC50 of 1.1, 3.4, 0.69, 2.6, 2.9 μg/mL. CAS No. 195051-23-1. Molecular formula: C33H34O13S. Mole weight: 670.68. | |
| BE-54238A | BE-54238A is a cytotoxic agent produced by Streptomyces sp. A54238. It has anti-proliferative effects on tumor cells such as P388, DLD4, PC-13, MKN-45, colon 26, etc., with IC50 of (μg/mL) 9.1, 3.5, 11.3, 8.1, 8.6. Synonyms: BE-54238 A; (-)-Be-54238a; 2-(5-Hydroxy-11-(1-hydroxyethyl)-4-methyl-6-oxo-1,4,6,9,10,11-hexahydro-2H-benzo(cd)pyrano(3,4-g)pyrrolo(1,2-a)indol-2-yl)acetic acid. CAS No. 205433-26-7. Molecular formula: C22H23NO6. Mole weight: 397.42. | |
| BE-54238B | BE-54238B is a cytotoxic agent produced by Streptomyces sp. A54238. It has anti-proliferative effects on tumor cells such as P388, DLD4, PC-13, MKN-45, colon 26, etc., with IC50 of (μg/mL) 58.2, 10.1, 53.2, 45.6, 20.5. Synonyms: BE-54238 B. CAS No. 205433-27-8. Molecular formula: C22H21NO6. Mole weight: 395.40. | |
| Belactosin A | Belactosin A is produced by the strain of Streptomyces sp. No antibacterial activity. A inhibits the IC50 of HeLa S3 cells is 51μmol/L. Synonyms: (alphaS,1S)-alpha-(L-Alanylamino)-2beta-[[[(2R)-3alpha-[(S)-sec-butyl]-4-oxooxetane-2beta-yl]carbonyl]amino]cyclopropane-1beta-propionic acid. Molecular formula: C17H27N3O6. Mole weight: 369.41. | |
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