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Amicetin B
It is produced by the strain of Streptomuces sp. R-285. The antibacterial activity was lower than that of Amicetin. Synonyms: Plicacetin; Benzamide, 4-amino-N-(1-(5-((4,6-dideoxy-4-(dimethylamino)-alpha-D-glucopyranosyl)oxy)tetrahydro-6-methyl-2H-pyran-2-yl)-1,2-dihydro-2-oxo-4-pyrimidinyl)-, (2R-(2-alpha,5-beta,6-alpha))-; DTXSID70962868; 4-amino-N-[1-[5-[5-(dimethylamino)-3,4-dihydroxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]-2-oxopyrimidin-4-yl]benzamide. CAS No. 43043-15-8. Molecular formula: C25H35N5O7. Mole weight: 517.57.
Amicetin C
It is produced by the strain of Streptomuces vinaceusdrappus. The antibacterial activity was lower than that of Amicetin. CAS No. 102646-94-6. Molecular formula: C56H94N10O19S. Mole weight: 1243.48.
Amiclenomycin
It is produced by the strain of Streptomyces lavendulae subsp. amiclenomycini. It can inhibit the activity of Mycobacterium, and also has effect on kanamycin resistant Mycobacterium nucleum. Biotin and Desthiobiocin can offset their activities. Synonyms: Amyclenomycin; 2-Amino-4-(4-amino-2,5-cyclohexadienyl)butyric acid. CAS No. 53696-70-1. Molecular formula: C10H16N2O2. Mole weight: 196.25.
Amicoumacin C
It is produced by the strain of Bacillus pumilus BN-103. It is an antibiotic that resists gram-positive bacteria. Synonyms: D-ribo-Hexar-6-amic acid, 3-amino-2,3-dideoxy-N-[1-(3,4-dihydro-8-hydroxy-1-oxo-1H-2-benzopyran-3-yl)-3-methylbutyl]-, γ-lactone, [S-(R*,R*)]-; AI 77Ba; D-ribo-Hexonic acid, 3-amino-2,?3,?6-trideoxy-6-[[(1S)?-1-[(3S)?-3,?4-dihydro-8-hydroxy-1-oxo-1H-2-benzopyran-3-yl]?-3-methylbutyl]?amino]?-6-oxo-, γ-lactone. CAS No. 77682-31-6. Molecular formula: C20H26N2O7. Mole weight: 406.43.
Amidepsin E
It is produced by the strain of Humicola sp. FO-5969. It has a weak inhibition of DGAT activity, and the IC50 of DGAT in rat liver microparticles is 124 ?ol/L, respectively. It has no toxicity to Raji cells and no antibacterial activity. Molecular formula: C30H31NO11. Mole weight: 581.57.
Amidepsine B
It is produced by the strain of Humicola sp. FO-2942. It inhibits DGAT activity, and the IC50 of rat liver microsomes DGAT is 19.2 X 10-6mol/L. It also inhibits triacylglycerol formation in intact Raji cells. CAS No. 169181-29-7. Molecular formula: C28H27NO11. Mole weight: 553.51.
Amidepsine C
It is produced by the strain of Humicola sp. FO-2942. It inhibits DGAT activity, and the IC50 of rat liver microsomes DGAT is 51.6 X 10-6mol/L. It also inhibits triacylglycerol formation in intact Raji cells. CAS No. 169181-30-0. Molecular formula: C30H31NO11. Mole weight: 581.57.
Amidinomycin
It is produced by the strain of Streptomyces flavochromogenes. Mainly resistant to gram-positive bacteria (weak). Mice were injected with Amidinomycin 18mg/kg and died within 7 to 10 days. Synonyms: Myxoviromycin; cis-N-(2-Amidinoethyl)-3-aminocyclopentanecarboxamide; cis-3-Amino-N-(3-amino-3-iminopropyl)cyclopentanecarboxamide. CAS No. 3572-60-9. Molecular formula: C9H18N4O. Mole weight: 198.26.
Amidomycin
It is produced by the strain of Streptomyces sp. PRL-1642. Mainly resistant to yeast and other fungi. Synonyms: Cyclo((2R)-2-hydroxy-3-methylbutanoyl-D-valyl-(2R)-2-hydroxy-3-methylbutanoyl-D-valyl-(2R)-2-hydroxy-3-methylbutanoyl-D-valyl-(2R)-2-hydroxy-3-methylbutanoyl-D-valyl). CAS No. 552-33-0. Molecular formula: C40H68N4O12. Mole weight: 796.98.
Aminocandin
Aminocandin, a new representative of the echinocandins, has broad-spectrum in vitro activity against Aspergillus and Candida spp. It is used as an anti-infective agent and antifungal drug. It acts by targeting glucans in the fungal cell walls. Synonyms: IP960; HMR3270; NXL201; L-Proline, 4-[(2-aminoethyl)amino]-N2-[[4'-(octyloxy)[1,1'-biphenyl]-4-yl]carbonyl]-L-ornithyl-L-threonyl-(4R)-4-hydroxy-L-prolyl-4-(4-hydroxyphenyl)-L-threonyl-L-seryl-3-hydroxy-4-methyl-, (6→15)-lactam, (3S,4S)-; N-[(2R,6S,9S,14aS,15S,16S,20S,23S,25aS)-11-[(2-Aminoethyl)amino]-2,15-dihydroxy-6-[(1R)-1-hydroxyethyl]-23-[(1R)-1-hydroxy-2-(4-hydroxyphenyl)ethyl]-20-(hydroxymethyl)-16-methyl-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl]-4'-(octyloxy)-4-biphenylcarboxamide. Grade: 95% by HPLC. CAS No. 227472-48-2. Molecular formula: C56H79N9O14. Mole weight: 1102.28.
Aminochloropentenedioic acid
It is produced by the strain of Streptomyces viridogenes MA5450. It has the activity of resisting gambogic micrococcus. Synonyms: [R-(Z)]-4-Amino-3-chloro-2-pentenedioic acid; 3-Acpa; 2-Amino-3-chloro-3-pentenedioic; 4-Amino-3-chloro-2-pentenedioic acid; 2-Pentenedioic acid, 4-amino-3-chloro-, (R-(Z))-. CAS No. 90288-29-2. Molecular formula: C5H6ClNO4. Mole weight: 179.56.
Aminoimidazole carboxamide
Aminoimidazole carboxamide is an imidazole derivative and a metabolite of antitumor drugs BIC and DIC. Synonyms: Aminoimidazole-4-carboxamide, 5-; 5-Aminoimidazole-4-carboxamide. Grade: > 95 % by HPLC. CAS No. 360-97-4. Molecular formula: C4H6N4O. Mole weight: 126.1.
Aminopyrrolnitrin
Aminopyrrolnitrin is a non-steroidal androgen-receptor antagonist produced by Pseudomonas sp. No. 2838. Synonyms: 3-Chloro-4-(2-amino-3-chlorophenyl)pyrrole; WB2838; WB 2838. Molecular formula: C10H8Cl2N2. Mole weight: 227.09.
Ammocidin
It is produced by the strain of Saccharothrix sp. AJ 9571. It can reduce the phosphorylation level of mitogen-activated protein kinase (MAPK)S6K. It induces apoptosis in Ras Ba/F3-V12 cells with an IC50 of 66 ng/mL, but not in IL-3 Ba/F3-V12 cells with 100 μg/mL. Synonyms: Ammocidin A. Molecular formula: C59H96O21. Mole weight: 1141.38.
Amphidinolide F
It is produced by the strain of Amphidinium magniviridis. The IC50 of mouse leukemia L1210 and human epidermal carcinoma KB cells were 1.5 and 3.2 μg/mL, respectively. Synonyms: 3,26,27-Trioxatricyclo(21.2.1.16,9)heptacos-13-ene-4,18,21-trione,10,11,16-trihydroxy-7,14,15,19-tetramethyl-12-methylene-2-(4-methyl-1,3-pentadienyl). CAS No. 139594-87-9. Molecular formula: C35H52O9. Mole weight: 616.78.
Amphistin
It is produced by the strain of Actinornycete KP-3052. It has weak antibacterial activity. Inhibition of melanoma cell B16 production of melanin without affecting the growth of the cell, IC50 is 55 μmol/L. Synonyms: amphistin. Molecular formula: C13H21N5O6. Mole weight: 343.33.
Amphotericin A
It is produced by the strain of Streptomyces nodosus. The antifungal spectrum is wide and the activity is strong. Synonyms: (4E,6E,8E,10E,14E,16E)-3-(4-amino-3,5-dihydroxy-6-methyloxan-2-yl)oxy-19,25,27,30,31,33,35,37-octahydroxy-18,20,21-trimethyl-23-oxo-22,39-dioxabicyclo[33.3.1]nonatriaconta-4,6,8,10,14,16-hexaene-38-carboxylic acid. Grade: ≥ 95%. CAS No. 1405-32-9. Molecular formula: C47H75NO17. Mole weight: 926.09.
Ampicillin Sodium Mixture With Sulbactam Sodium
Ampicillin Sodium Mixture with Sulbactam Sodium is a β-lactamase inhibitor used to enhance the effectiveness of β-lactam antibiotics. Synonyms: Unacyne; Unacid; Unasyn-S; Yucion-S. CAS No. 117060-71-6. Molecular formula: C25H29N3Na2O9S2. Mole weight: 625.62.
Ampullosporin A is produced by the strain of Sepedonium ampullosporum HKI-0053. Its antibacterial spectrum is narrow. The anti-staphylococcus aureus GS511, Bacillus subtilis, Pseudomonas aeruginosa K599/WT, Escherichia coli SG458, Ocher sporococcus SBUG 549 and Deep red yeast and other bacteria and fungi had only moderate intensity activity, and had no effect on other yeast and candida albicans. It can cause Phoma destructiva to form pigment. Its content is greater than 1mg/kg, which can cause hypothermia and reduce automatic exercise in rats. Synonyms: N-Acetyl-L-tryptophyl-L-alanyl-2-methylalanyl-2-methylalanyl-L-leucyl-2-methylalanyl-L-glutaminyl-2-methylalanyl-2-methylalanyl-2-methylalanyl-L-glutaminyl-L-leucyl-2-methylalanyl-N1-[(1S)-1-(hydroxymethyl)-3-methylbutyl]-L-glutamamide. CAS No. 197960-94-4. Molecular formula: C77H127N19O19. Mole weight: 1622.94.
Amudol
It is produced by the strain of Penicillum martensii. It has a weak antibacterial activity against S. aureus, E. coli, salmonella, etc. Synonyms: 2,5-Dihydroxy-4-chlorbenzylalkohol. CAS No. 31302-46-2. Molecular formula: C7H7ClO3. Mole weight: 174.58.
Amycin A
It is produced by the strain of Streptomyces sp. DSM 3816. The activity of Amycin A is weaker than that of Amycin B. CAS No. 116296-63-0. Molecular formula: C62H105N3O21. Mole weight: 1228.50.
Amycin B
It is produced by the strain of Streptomyces sp. DSM 3816. It has the activity of anti-ringworm, microspora, candida, aspergillus and other fungi and gram-positive bacteria such as staphylococcus and streptococcus. Synonyms: Scopafungin, 23-O-de(carboxyacetyl)-8,47-didemethyl-14,49-dimethyl-. CAS No. 129313-99-1. Molecular formula: C56H101N3O15. Mole weight: 1056.41.
Amylostatin J
It is produced by the strain of Streptomyces diastaticus var. amylostaticus. It can inhibit the activity of Glucoamylase. CAS No. 79305-08-1. Molecular formula: C25H48NO15. Mole weight: 602.64.
Amylostatin K
It is produced by the strain of Streptomyces diastaticus var. amylostaticus. It can inhibit the activity of Glucoamylase. CAS No. 82642-64-6. Molecular formula: C25H43NO18. Mole weight: 645.61.
Amylostatin L
It is produced by the strain of Streptomyces diastaticus var. amylostaticus. It can inhibit the activity of Glucoamylase. CAS No. 82642-66-8. Molecular formula: C31H53NO23. Mole weight: 807.74.
Amylostatin M
It is produced by the strain of Streptomyces diastaticus var. amylostaticus. It can inhibit the activity of Glucoamylase. CAS No. 82642-67-9. Molecular formula: C31H53NO23. Mole weight: 807.74.
Amylostatin N
It is produced by the strain of Streptomyces diastaticus var. amylostaticus. It can inhibit the activity of Glucoamylase. CAS No. 82642-69-1. Molecular formula: C37H63NO28. Mole weight: 969.88.
Amythiamicin B
It is produced by the strain of Amycolatopsis sp. M481-42F4. It has activity against gram-positive bacteria including Multidrug resistant Staphylococcus aureus and Methicillin-resistant Staphylococcus aureus (MR-SA)(MIC 0.1-0.78μg/mL). Not resistant to gram-negative bacteria and fungi. Synonyms: L-Prolinamide, N-((2-(10,11,17,18,23,24,25,26,27,28-decahydro-14-methyl-11-(2-(methylamino)-2-oxoethyl)-18,28-bis(1-methylethyl)-9,16,23,26-tetraoxo-9H,16H-8,5:15,12:22,19:32,29:36,33-pentanitrilo-5H,29H,33H-pyrido(3,2-a1)(1,11,18,25,31,4,7,14,21)pentathiatetraazacyclotetratriacontin-2-yl)-4-thiazolyl)carbonyl)-L-seryl-. CAS No. 156620-48-3. Molecular formula: C50H53N15O9S6. Mole weight: 1200.44.
Amythiamicin C
It is produced by the strain of Amycolatopsis sp. M481-42F4. It has activity against gram-positive bacteria including Multidrug resistant Staphylococcus aureus and Methicillin-resistant Staphylococcus aureus (MR-SA)(MIC 0.1-0.78μg/mL). Not resistant to gram-negative bacteria and fungi. Synonyms: 4-Thiazolecarboxylic acid,2-(10,11,17,18,23,24,25,26,27,28-decahydro-14-methyl-11-(2-methylamino)-2-oxoethyl)-18,28-bis(1-methylethyl)-9,16,23,26-tetraoxo-9H,16H-8,5:15,12:22,19:32,29:36,33-pentanitrilo-5H,29H,33H-pyrido(3,2-a1)(1,11,18,25,31,4,7,14,21)pentathiatetraazacyclotetratriacontin-2-yl)-,(octahydro-1,4-dioxopyrrolo(1,2-a)pyrazin-3-yl)methyl ester. CAS No. 156620-47-2. Molecular formula: C50H50N14O9S6. Mole weight: 1183.41.
Amythiamicin D
It is produced by the strain of Amycolatopsis sp. M481-42F4. It has activity against gram-positive bacteria including Multidrug resistant Staphylococcus aureus and Methicillin-resistant Staphylococcus aureus (MR-SA)(MIC 0.1-0.78μg/mL). Not resistant to gram-negative bacteria and fungi. Synonyms: 4-Thiazolecarboxylic acid,2-(10,11,17,18,23,24,25,26,27,28-decahydro-14-methyl-11-(2-(methylamino)-2-oxoethyl)-18,28-bis(1-methylethyl)-9,16,23,26-tetraoxo-9H,16H-8,5:15,12:22,19:32,29:36,33-pentanitrilo-5H,29H,33H-pyrido(3,2-a1)(1,11,18,25,31,4,7,14,21)pentathiatetraazacyclotetratriacontin-2-yl)-,methyl ester. CAS No. 156620-46-1. Molecular formula: C43H42N12O7S6. Mole weight: 1031.26.
Anantin
It is produced by the strain of Streptomyces coerulescens. It has a competitive binding to the cardiac natriuretic peptide (ANF) receptor. Synonyms: Anantin (9CI); CYCLO[GLY-PHE-ILE-GLY-TRP-GLY-ASN-BETA-ASP]-ILE-PHE-GLY-HIS-TYR-SER-GLY-ASP-PHE; GLY-PHE-ILE-GLY-TRP-GLY-ASN-ASP-ILE-PHE-GLY-HIS-TYR-SER-GLY-ASP-PHE; H-GLY-PHE-ILE-GLY-TRP-GLY-ASN-ASP-ILE-PHE-GLY-HIS-TYR-SER-GLY-ASP-PHE-OH; ANANTIN. Grade: 95%. CAS No. 133658-45-4. Molecular formula: C90H111N21O24. Mole weight: 1870.97.
Andrastin B
It is produced by the strain of Penicillum sp. FO-3929. It can inhibit PFTase. IC50 is 47.1 μmol/L. Synonyms: CHEBI:142862; methyl (3beta,5beta,8alpha,9beta,10alpha,13alpha)-3-(acetyloxy)-15,19-dihydroxy-4,4,8,12,16-pentamethyl-17-oxoandrosta-11,15-diene-14-carboxylate; methyl 3beta-(acetyloxy)-15,19-dihydroxy-4,4,8,12,16-pentamethyl-17-oxo-5beta,8alpha,9beta,10alpha,13alpha-androsta-11,15-diene-14-carboxylate. Molecular formula: C28H40O7. Mole weight: 488.61.
Andrastin C
It is produced by the strain of Penicillum sp. FO-3929. It can inhibit PFTase. IC50 is 13.3 μmol/L. Molecular formula: C28H40O6. Mole weight: 472.61.
Andrastin D
It is produced by the strain of Penicillum sp. FO-3929. It can inhibit PFTase. IC50 is 25.7 μmol/L. Synonyms: CHEBI:142874; methyl (5beta,8alpha,9beta,10alpha,13alpha)-15-hydroxy-4,4,8,12,16-pentamethyl-3,17-dioxoandrosta-11,15-diene-14-carboxylate; methyl 15-hydroxy-4,4,8alpha,12,16-pentamethyl-3,17-dioxo-5beta,9beta,10alpha,13alpha-androsta-11,15-diene-14-carboxylate. CAS No. 184432-08-4. Molecular formula: C26H37O5. Mole weight: 429.57.
Andrimid
It is produced by the strain of Pseudomonas fluorescens. It has anti-gram-positive bacterial activity, has weak effect on gram-negative fine bacteria due to low membrane permeability, and has strong effect on Xanthomonas campestris causing rice crop wilt. CAS No. 108868-95-7. Molecular formula: C27H33N3O5. Mole weight: 479.57.
It is produced by the strain of Angiococcus disciformis An d30. Interfered with protein synthesis and had anti-gram-positive bacterial activity. Synonyms: 1-Oxa-9-azacyclononadec-17-6,8,13,19-tetrone, 15-hydroxy-2-(6-hydroxy-3,7-dimethyl-1,7,9-decatrienyl)-5,10,14,18-pentamethyl-, (2R-(2R*(1E,3S*,6S*,7E),5S*,10R*,14R*,15S*,16S*,17Z))-. CAS No. 99267-41-1. Molecular formula: C34H53NO7. Mole weight: 587.79.
Angiostatin
It is produced by the strain of Dihetrospora catenulata SANK 10481, D. chlamidospora SANK 12181, Verticillum viveostratosum SANK 13358. It has the function of inhibiting Angiotensin converting enzyme. Synonyms: ANGIO. CAS No. 86090-08-6. Molecular formula: C9H14N2O8. Mole weight: 278.21.
Anguibactin
It is produced by the strain of Vibrio angullarum. It is an antibiotic that acts as a Siderophore and has a very strong affinity with Fe+3. Synonyms: (2Z)-N-hydroxy-2-(5-hydroxy-6-oxo-1-cyclohexa-2,4-dienylidene)-N-[2-(3H-imidazol-4-yl)ethyl]thiazolidine-4-carboxamide; ACMC-20m71m; (2Z)-N-hydroxy-2-(5-hydroxy-6-oxocyclohexa-2,4-dien-1-ylidene)-N-[2-(1H-imidazol-5-yl)ethyl]-1,3-thiazolidine-4-carboxamide. CAS No. 104245-09-2. Molecular formula: C15H16N4O4S. Mole weight: 348.38.
Anguinomycin B
It is produced by the strain of Streptomyces sp. R2827 and R2827-2. It has anti-mouse Lewis lung cancer and P388 leukemia activity, and in vivo test shows that B has a strong anti-cancer effect on mouse solid cancer. It has been reported that it can stop normal cell growth and cause deformable cell death. Synonyms: KR-2827A; 2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-6-oxo-2H-pyran-2-yl)-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-8-oxo-. CAS No. 111278-00-3. Molecular formula: C32H46O6. Mole weight: 526.70.
Anhydrochlortetracycline is an impurity in the tetracycline antibiotic chlortetracycline, which is formed from tetracycline in an acidic environment. Synonyms: Anhydroaureomycin. CAS No. 4497-8-9. Molecular formula: C22H21ClN2O7. Mole weight: 460.86.
Anhydroepiophiobolin A
Anhydroepiophiobolin A is an ophiobolin with a broad biological profile. It has antibacterial, antifungal, antitumour, herbicidal and nematocidal activities. It is the major terminal degradation product of ophiobolin A and is co-produced with other ophiobolins in many bipolaris species. Synonyms: (6α,18R)-14,18-epoxy-5-oxo-ophiobola-3,7,19-trien-25-al; (2'S,3'S,3aR,5'R,6aR,9aS,10aR)-2,3a,4,4',5',6a,7,9a,10,10a-decahydro-3',9,10a-trimethyl-5'-(2-methyl-1-propen-1-yl)-7-oxospiro[dicyclopenta[a,d]cyclooctene-3(1H),2'(3'H)-furan]-6-carboxaldehyde; 3-Anhydro-6-epi-ophiobolin A; [3S-[3α(3'R*,5'S*),3aα,6aα,9aβ,10aβ]]-1,3a,4,4',5',6a,7,9a,10,10a-decahydro-3',9,10a-trimethyl-5'-(2-methyl-1-propenyl)-7-oxospiro[dicyclopenta[a,d]cyclooctene-3(2H),2'(3'H)-furan]-6-carboxaldehyde. Grade: >98% by HPLC. CAS No. 90411-20-4. Molecular formula: C25H34O3. Mole weight: 382.54.
Anhydroexfoliamycin
Anhydroexfoliamycin is a naphthoquinone antibiotic produced by Streptomyces exfoliamycin Tu 1424. Activity against gram-positive bacteria. CAS No. 148084-39-3. Molecular formula: C22H24O8. Mole weight: 416.42.
Anhydrofulvic acid
In acidic condition, Anhydrofulvic acid inhibits mitochondrial respiration of Candida utilis using both succinate and cytochrome C as respiratory substrates, but not using NADH. Anhydrofulvic acid has antifungal activity. Synonyms: 1H,10H-Pyrano[4,3-b][1]benzopyran-9-carboxylic acid, 7,8-dihydroxy-3-methyl-10-oxo-; 7,8-dihydroxy-3-methyl-10-oxo-1H-pyrano[4,3-b]chromene-9-carboxylic acid. CAS No. 95730-85-1. Molecular formula: C14H10O7. Mole weight: 290.23.
Anhydroophiobolin A
It is the dehydrated analogue of ophiobolin A and a major member of the ophiobolin complex of phytotoxic metabolites produced by many species of the genus bipolaris. It possesses a broad biological profile with antibacterial, antifungal, antitumour, herbicidal and nematocidal activities. Synonyms: 14,17-Epoxy-5-oxo-3,7,18-ophiobolatrien-21-al; Anhydroophiobolin; (18R)-5-Oxo-14,18-epoxy-3,4-didehydroophiobola-7,19-diene-25-al; (2'S,3'S,3aR,5'R,6aS,9aS,10aR)-2,3a,4,4',5',6a,7,9a,10,10a-Decahydro-3',9,10a-trimethyl-5'-(2-methyl-1-propen-1-yl)-7-oxospiro[dicyclopenta[a,d]cyclooctene-3(1H),2'(3'H)-furan]-6-carboxaldehyde; [3S-[3α(3'R*,5'S*),3aα,6aβ,9aβ,10aβ]]-1,3a,4,4',5',6a,7,9a,10,10a-Decahydro-3',9,10a-trimethyl-5'-(2-methyl-1-propenyl)-7-oxo-spiro[dicyclopenta[a,d]cyclooctene-3(2H),2'(3'H)-furan]-6-carboxaldehyde; 3-Anhydro-cochliobolin; 3-Anhydroophiobolin A. Grade: >95% by HPLC. CAS No. 6026-65-9. Molecular formula: C25H34O3. Mole weight: 382.54.
Anicequol
It is produced by the strain of Penicillum aurantiogriseum Die-rckx TP-F0213. It can inhibit Colon cancer DLD-1 Cells that do not depend on adherent growth with IC50 of 1.2 μg/mL, and cells that depend on adherent growth with IC50 of 40 μg/mL. Synonyms: NGA0187; (3β,5α,7β,11β,24S)-16-acetoxy-3,7,11-trihydroxyergost-22-en-6-one. CAS No. 440368-05-8. Molecular formula: C30H48O6. Mole weight: 504.70.
Ansamitocin derivative TN-006
Ansamitocin derivative TN-006 is a derivative of Ansamitocin, a family of polyketide antibiotics comprising a naphthalene/benzene or napthaquinone/benzoquinone ring system bridged at nonadjacent positions by an aliphatic chain. Synonyms: PDM3. CAS No. 72902-38-6. Molecular formula: C31H41ClN2O9. Mole weight: 621.1.
Ansamitocin PDM-3
Ansamitocin PDM-3 is an ansamycin antibiotic isolated from Actinosynnema pretiosum, and exhibits antitumor activity. Synonyms: Ansamitocin P-3; N-Demethylansamitocin P 3; N-Demethylansamitocin P-3. CAS No. 77353-69-6. Molecular formula: C31H41ClN2O9. Mole weight: 621.1.
Ansamitocin PHO-0
It is produced by the strain of Streptamyces sclerotialus, Str. flavochromogenes, Str. flaviscleroticus, Str. luridus, Chainia nigra, Strertosporangium roseurn, Nocardia sp. N-1231. It has antiprotozoal and antitumor activity. Synonyms: Maytansine, 3-O-de[2-(acetylmethylamino)-1-oxopropyl]-15-hydroxy-, (15R)-; (15R)-3-O-De[2-(acetylmethylamino)-1-oxopropyl]-15-hydroxymaytansine; 4,24-Dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosane, maytansine deriv.; Antibiotic C 15003PHO0. CAS No. 79082-29-4. Molecular formula: C28H37N2O9Cl. Mole weight: 581.05.
Ansamitocin PHO-1
It is produced by the strain of Streptamyces sclerotialus, Str. flavochromogenes, Str. flaviscleroticus, Str. luridus, Chainia nigra, Strertosporangium roseurn, Nocardia sp. N-1231. It has antiprotozoal and antitumor activity. Synonyms: Maytansine, 3-O-acetyl-3-O-de[2-(acetylmethylamino)-1-oxopropyl]-15-hydroxy-, (15R)-; (15R)-3-O-Acetyl-3-O-de[2-(acetylmethylamino)-1-oxopropyl]-15-hydroxymaytansine; 4,24-Dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosane, maytansine deriv.; Antibiotic C 15003PHO1. CAS No. 79056-16-9. Molecular formula: C30H39N2O10Cl. Mole weight: 623.10.
Ansamitocin PHO-2
It is produced by the strain of Streptamyces sclerotialus, Str. flavochromogenes, Str. flaviscleroticus, Str. luridus, Chainia nigra, Strertosporangium roseurn, Nocardia sp. N-1231. It has antiprotozoal and antitumor activity. Synonyms: Maytansine, 2'-de(acetylmethylamino)-15-hydroxy-, (15R)-(9CI); 4,24-Dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosane, maytansine deriv.; Antibiotic C 15003PHO2. CAS No. 79028-00-5. Molecular formula: C31H41N2O10Cl. Mole weight: 637.13.
Ansamitocin PHO-3
It is produced by the strain of Streptamyces sclerotialus, Str. flavochromogenes, Str. flaviscleroticus, Str. luridus, Chainia nigra, Strertosporangium roseurn, Nocardia sp. N-1231. It has antiprotozoal and antitumor activity. Synonyms: Maytansine, 2'-de(acetylmethylamino)-15-hydroxy-2'-methyl-, (15R)-(9CI); 4,24-Dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosane, maytansine deriv.; Antibiotic C 15003PHO3. CAS No. 79082-28-3. Molecular formula: C32H43N2O10Cl. Mole weight: 651.15.
Ansamitocin PHO-4
It is produced by the strain of Streptamyces sclerotialus, Str. flavochromogenes, Str. flaviscleroticus, Str. luridus, Chainia nigra, Strertosporangium roseurn, Nocardia sp. N-1231. It has antiprotozoal and antitumor activity. Synonyms: Maytansine, 3-O-de[2-(acetylmethylamino)-1-oxopropyl]-15-hydroxy-3-O-(3-methyl-1-oxobutyl)-,(15R)-; (15R)-3-O-De[2-(acetylmethylamino)-1-oxopropyl]-15-hydroxy-3-O-(3-methyl-1-oxobutyl)maytansine; 4,24-Dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosane, maytansine deriv.; Antibiotic C 15003PHO4. CAS No. 79056-15-8. Molecular formula: C33H45N2O10Cl. Mole weight: 665.18.
Anthelvencin A
It is produced by the strain of Streptomyces venezuelae. It has the activity of resisting gram positive bacterium, negative bacterium, mycobacterium, yeast and ringworm, has the inhibition to vaccinia virus, dysentery amoeba, and has the effect of repelling nematode in mice. Synonyms: (4S)-(+)-Anthelvencin A; NSC624528; (S)-Anthelvencin A; LS-20251; {4-[((5S)-2-amino(1-pyrrolin-5-yl))carbonylamino]pyrrol-2-yl}-N-{5-[N-(2-amidinoethyl)carbamoyl]-1-methylpyrrol-3-yl}carboxamide. CAS No. 58616-25-4. Molecular formula: C19H25N9O3. Mole weight: 427.46.
Anthelvencin B
It is produced by the strain of Streptomyces venezuelae. It has the activity of resisting gram positive bacterium, negative bacterium, mycobacterium, yeast and ringworm, has the inhibition to vaccinia virus, dysentery amoeba, and has the effect of repelling nematode in mice. Synonyms: Anthelvencine B; DTXSID30911498; N-[5-({5-[(3-Amino-3-iminopropyl)carbamoyl]-1-methyl-1H-pyrrol-3-yl}carbamoyl)-1-methyl-1H-pyrrol-3-yl]-5-iminopyrrolidine-2-carboximidic acid. CAS No. 11011-26-0. Molecular formula: C20H27N9O3. Mole weight: 441.49.
Anthranilamide
It is produced by the strain of Streptomyces sp. B7747. Antichlorella activity. MIC is 20-107μg/mL. Synonyms: 2-AMINOBENZAMIDE; Benzamide, 2-amino-; o-Aminobenzamide; 2-Carbamoylaniline; Aminobenzamide; Anthranilimidic acid. Grade: 95 %. CAS No. 88-68-6. Molecular formula: C7H8N2O. Mole weight: 136.15.
Anthranilamide 1b
It is produced by the strain of Streptomyces sp. B7747. Antichlorella activity. MIC is 20-107μg/mL. Anthranilamide 1b is more active than the corresponding free acid. All the anthranilamide has no antibacterial activity against Staphylococcus aureus, Escherichia coli and Mucor mirabilis. Molecular formula: C15H14NO3. Mole weight: 256.28.
Anthranilamide 1c
It is produced by the strain of Streptomyces sp. B7747. Antichlorella activity. MIC is 20-107μg/mL. All the anthranilamide has no antibacterial activity against Staphylococcus aureus, Escherichia coli and Mucor mirabilis. Synonyms: 2-[methyl-(3-phenylpropionyl)lamino]-benzoic acid. CAS No. 207305-65-5. Molecular formula: C17H17NO3. Mole weight: 283.33.
Anthranilamide 1f
It is produced by the strain of Streptomyces sp. B7747. Antichlorella activity. MIC is 20-107μg/mL. Anthranilamide 1f is more active than the corresponding free acid. All the anthranilamide has no antibacterial activity against Staphylococcus aureus, Escherichia coli and Mucor mirabilis. Molecular formula: C18H19NO3. Mole weight: 297.35.
Anthranilamide 2b
It is produced by the strain of Streptomyces sp. B7747. Antichlorella activity. MIC is 20-107μg/mL. Anthranilamide 2b is more active than the corresponding free acid. All the anthranilamide has no antibacterial activity against Staphylococcus aureus, Escherichia coli and Mucor mirabilis. Molecular formula: C18H17NO3. Mole weight: 295.33.
Anthrotainin
Anthrotainin is a substance P (Substance P, SP) binding inhibitor produced by Gliocladium catenulatum. Synonyms: (4aR,12aR)-1,4a,10,11,12a-pentahydroxy-8-methoxy-3,12-dioxo-4,5-dihydrotetracene-2-carboxamide; 2-Naphthacenecarboxamide, 3,4,4a,5,12,12a-hexahydro-1,4a,10,11,12a-pentahydroxy-8-methoxy-3,12-dioxo-, (cis)-. CAS No. 148084-40-6. Molecular formula: C20H17NO9. Mole weight: 415.35.
Antiamoebin
Antiamoebin is a peptide antibiotic produced by the fungus Emericellopsis poonensis. Antiamoebin mainly resists dysentery amoeba, Trichomonas vaginalis, Hymenoptera, Trypanosoma and other protozoa, without antibacterial effect. Synonyms: Antiamoebin I. CAS No. 12692-85-2. Molecular formula: C80H123N17O20. Mole weight: 1642.93.
Antibiotic 0231A
It is a 3-α-hydroxysteroid dehydrogenase inhibitor produced by the strain of Strptomyces sp. HKI 0231. It can inhibit 3-α-hydroxysteroid dehydrogenase with IC50 of 10.5 μg/mL. It has weak antimicrobial and antifungal activity (MIC is less than 100 μg/mL). Synonyms: 0231A; Benz[cd]isoindolo[2,1-a]indol-1(8H)-one, 8,8,9-trimethoxy-5-methyl-. CAS No. 357924-11-9. Molecular formula: C22H19NO4. Mole weight: 361.39.
Antibiotic 0231B
It is a 3-α-hydroxysteroid dehydrogenase inhibitor produced by the strain of Strptomyces sp. HKI 0231. It can inhibit 3-α-hydroxysteroid dehydrogenase with IC50 of 2.5 μg/mL. It has weak antimicrobial and antifungal activity (MIC is less than 100 μg/mL). Synonyms: 0231B; Benz[cd]isoindolo[2,1-a]indol-1(8H)-one, 8,9-dimethoxy-5-methyl-. CAS No. 357924-12-0. Molecular formula: C21H17NO3. Mole weight: 331.36.
Antibiotic 02-3D
It is a tryptomycin antibiotic produced by the strain of Streptomyces avellaneus 02-3. It inhibits P388 murine leukemia cells with IC50 of 12 μg/mL. Synonyms: 02-3D; 4A-deacetylchromomycin A3. CAS No. 132243-19-7. Molecular formula: C55H80O25. Mole weight: 1141.21.
Antibiotic 02-3G
It is a tryptomycin antibiotic produced by the strain of Streptomyces avellaneus 02-3. It inhibits P388 murine leukemia cells with IC50 of 0.60 μg/mL. Synonyms: 02-3G; 4A,4E-Dideacetylchromomycin A3. CAS No. 132243-20-0. Molecular formula: C53H78O24. Mole weight: 1099.17.
Antibiotic 1100-50
It is produced by the strain of Streptomyces lavendulae SANK-64297. It is a nematocidal substance. Synonyms: 1100-50. Molecular formula: C31H56N6O15P2. Mole weight: 814.75.
Antibiotic 1233B
It is a β-lactone antibiotic produced by the strain of Cephalosporium sp. It has a strong inhibitory effect on hydroxymethyl glutaryl coenzyme A (HMG-CoA) synthase. Synonyms: 1233B; 3,5,7-trimethyl-12-hydroxy-13-hydroxymethyl-2,4-tetradecadiendioic acid; 2,4-Tetradecadienedioic acid, 12-hydroxy-13-(hydroxymethyl)-3,5,7-trimethyl-. CAS No. 34668-58-1. Molecular formula: C18H30O6. Mole weight: 342.43.