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Asparaginyl-lysine
Asparaginyl-Lysine is a dipeptide composed of asparagine and lysine. Synonyms: Asn-Lys; NK dipeptide. CAS No. 22677-58-3. Molecular formula: C10H20N4O4. Mole weight: 260.29.
Asparaginyl-phenylalanine
Asparaginyl-Phenylalanine is a dipeptide composed of asparagine and phenylalanine. Synonyms: L-Asparaginyl-L-phenylalanine; Asn-Phe. CAS No. 22849-01-0. Molecular formula: C13H17N3O4. Mole weight: 279.29.
Asparaginyl-proline
Asparaginyl-proline is a dipeptide composed of asparagine and proline. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: L-Proline, 1-L-asparaginyl-; H-NP-OH; L-asparagyl-L-proline; Asn-Pro; L-Asn-L-Pro. Grade: ≥95%. CAS No. 78346-95-9. Molecular formula: C9H15N3O4. Mole weight: 229.23.
Asparaginyl-serine
Asparaginyl-serine is a dipeptide composed of asparagine and serine. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: L-Serine, L-asparaginyl-; Asn-Ser; L-Asn-L-Ser; L-Asparaginyl-L-serine; H-NS-OH; Asparaginylserine. Grade: ≥95%. CAS No. 92172-15-1. Molecular formula: C7H13N3O5. Mole weight: 219.20.
Asparaginyl-tryptophan
Asparaginyl-tryptophan is a dipeptide composed of asparagine and tryptophan. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: L-Tryptophan, L-asparaginyl-; H-NW-OH; L-asparagyl-L-tryptophan; Asn-Trp; Asparaginyltryptophan; L-Tryptophan, N-L-asparaginyl-. Grade: ≥95%. CAS No. 74105-03-6. Molecular formula: C15H18N4O4. Mole weight: 318.33.
Asparenomycin A
Asparenomycin A is a carbapenem antibiotic produced by Streptomyces tokunonensis sp. (PA-31088) and Srt.argenteolus (PA-39504). It has anti-gram-positive and negative bacteria activity, can inhibit a variety of β-lactamases, and also has an effect on β-lactamase-producing strains. Synonyms: Asparenomycin. CAS No. 76466-24-5. Molecular formula: C14H16N2O6S. Mole weight: 340.35.
Asparenomycin B
Asparenomycin B is a carbapenem antibiotic produced by Streptomyces tokunonensis sp. (PA-31088) and Srt.argenteolus (PA-39504). It has anti-gram-positive and negative bacteria activity, can inhibit a variety of β-lactamases, and also has an effect on β-lactamase-producing strains. CAS No. 79366-72-6. Molecular formula: C14H18N2O6S. Mole weight: 342.37.
Asparenomycin C
Asparenomycin C is a carbapenem antibiotic produced by Streptomyces tokunonensis sp. (PA-31088) and Srt.argenteolus (PA-39504). It has anti-gram-positive and negative bacteria activity, can inhibit a variety of β-lactamases, and also has an effect on β-lactamase-producing strains. CAS No. 81018-71-5. Molecular formula: C14H16N2O5S. Mole weight: 324.35.
Aspartyl-Histidine is a dipeptide composed of aspartate and histidine. Synonyms: Asp-His; L-alpha-aspartyl-L-histidine. CAS No. 22677-56-1. Molecular formula: C10H14N4O5. Mole weight: 270.24.
Aspartyl-serine is a dipeptide composed of aspartic acid and serine. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: L-Serine, L-a-aspartyl-; Aspartylserine; (S)-3-Amino-N-((S)-1-carboxy-2-hydroxy-ethyl)-succinamic acid; Asp-Ser; α-L-Asparagyl-L-serine; L-Asp-L-Ser; H-DS-OH; L-alpha-aspartyl-L-serine; (S)-3-amino-4-(((S)-1-carboxy-2-hydroxyethyl)amino)-4-oxobutanoic acid. Grade: ≥95%. CAS No. 6403-13-0. Molecular formula: C7H12N2O6. Mole weight: 220.18.
Aspartyl-threonine
Aspartyl-Threonine is a dipeptide composed of aspartate and threonine. Synonyms: aspartylthreonine; Asp-Thr; DT dipeptide; D-T Dipeptide. CAS No. 13433-17-5. Molecular formula: C8H14N2O6. Mole weight: 234.21.
Asperaldin
Asperaldin is an aldose reductase (ECLLL21) inhibitor produced by Aspergillus niger CFR-1046. Synonyms: 1,4-Naphthalenedione, 8-(hexyloxy)-2,6-dihydroxy-. CAS No. 561297-46-9. Molecular formula: C16H18O5. Mole weight: 290.31.
Aspercolorin
An atypical cyclic tetrapeptide in which one of the amino acids is a 5-methoxyanthranilic acid. Aspercolorin is a fungal metabolite produced by Aspergillus versicolor. It is used as a secondary metabolite standard in polyphasic taxonomy for the identification of aspergillus versicolor. Synonyms: 1,2,3,5,6,7,8,9,10,11,12,17,18,18a-Tetradecahydro-10-benzyl-14-methoxypyrrolo[1,2-a][1,4,8,11]benzotetraazacyclotetradecine-5,9,12,18-tetrone; 10-benzyl-14-methoxy-1,2,3,7,8,10,11,18a-octahydrobenzo[e]pyrrolo[1,2-a][1,4,8,11]tetraazacyclotetradecine-5,9,12,18(6H,17H)-tetraone; Cyclo(β-alanylprolyl-2-amino-5-methoxybenzoylphenylalanyl). Grade: >97% by HPLC. CAS No. 29123-52-2. Molecular formula: C25H28N4O5. Mole weight: 464.51.
Aspergillic acid
Aspergillic acid is an antibiotic produced by Aspergillus flavus. Aspergillic acid has anti-gram-positive bacteria, gram-negative bacteria, mycobacteria and Candida albicans activities. Synonyms: 3-Isobutyl-6-sec-butyl-2-hydroxypyrazine 1-oxide. CAS No. 490-02-8. Molecular formula: C12H20N2O2. Mole weight: 224.30.
Aspergillimide
Aspergillimide is a product produced by Aspergillus sp. IMI 337664 with anthelmintic effect. Synonyms: Asperparaline A; (1R,3'R,5aR,8aR,9aS)-rel-(-)-tetrahydro-1,1',8,8,11-pentamethyl-spiro[5H,6H-5a,9a-(iminomethano)-1H-cyclopent[f]indolizine-7(8H),3'-pyrrolidine]-2',5',10-trione; VM 55598; Antibiotic VM 55598. Grade: >98%. CAS No. 195966-93-9. Molecular formula: C20H29N3O3. Mole weight: 359.46.
Aspergillin PZ
Asperillin PZ is an isoindole fungal metabolite produced by Aspergillus awamoli. 0.089 μmol/L can cause the morphological changes of the conidia of Pear spores. It may possess anti-cancer and anti-tumor properties. Synonyms: (1R,2S,5R,5aS,5bS,8R,8aS,9R,11aR,13aR)-2,3,4,5,5a,5b,8,8a,9,10,13,13a-Dodecahydro-2-hydroxy-5,7,8-trimethyl-9-(2-methylpropyl)-1,5-epoxy-1H-cyclohepta[3,4]benz[1,2-d]isoindole-11,12-dione; (+)-Aspergillin PZ; Aspergilline PZ. Grade: >98%. CAS No. 483305-08-4. Molecular formula: C24H35NO4. Mole weight: 401.54.
Aspergillumarin
Aspergillus A is a dihydroisocoumarin derivative isolated from the culture broth of the marine-derived fungus Aspergillus. CAS No. 1392495-06-5. Molecular formula: C14H16O4. Mole weight: 248.27.
Aspergin
Aspergin is an antibiotic produced by Aspergillus sp., with activity against gram-positive bacteria. CAS No. 40434-07-9. Molecular formula: C19H26O3. Mole weight: 302.41.
Asperlactone
Asperlactone is a biologically active polyketide metabolite produced mainly from Aspergillus westerdijkiae. Asperlactone is a nematicidal, an insecticidal, an antibacterial and an antifungal agent. Synonyms: 2(5H)-Furanone, 5-((1S)-1-hydroxyethyl)-3-((2S,3S)-3-methyloxiranyl)-, (5R)-; [2S-[2α[S*(R*)],3β]]-5-(1-hydroxyethyl)-3-(3-methyloxiranyl)-2(5H)-furanone. Grade: ≥98%. CAS No. 76375-62-7. Molecular formula: C9H12O4. Mole weight: 184.19.
Asperlicin
Asperlicin is a non-peptide cholecystokinin (Cholecystokinin, CCK) produced by Aspergillus alliaceus. It has the effect of antagonizing CCK. A and its derivatives are promising for the treatment of ulcers and pancreatic tumors. Synonyms: Asperlicin A. CAS No. 93413-04-8. Molecular formula: C31H29N5O4. Mole weight: 535.59.
Asperphenamate
Asperphenamate is a fungal secondary metabolite isolated from Aspergillus flavipes. Asperphenamate has been found in a broad range of Pencillium and Aspergillus species and even in plants, as a product of endophytic fungi. Asperphenamate has weak antitumor activity. It inhibits proliferation of T47D and MDA-MB-231 breast and HL-60 leukemia cancer cell lines (IC50s = 92.3, 96.5, and 97.9 μM, respectively) and inhibits yeast α-glucosidase activity (IC50 = 8.3 μM). Asperphenamate is also used to synthesize N-Benzoyl-O-(N'-(1-benzyloxycarbonyl-4-piperidiylcarbonyl)-D-phenylalanyl)-D-phenylalaninol (BBP), an asperphenamate derivative that inhibits human breast carcinoma MCF-7 cell growth. Synonyms: (S)-N-Benzoyl-L-phenylalanine 2-(Benzoylamino)-3-phenylpropyl Ester; N-Benzoyl-phenylalanine 2-benzoylamino-3-phenylpropyl Ester; N-Benzoyl-L-phenylalaninol N-benzoyl-L-phenylalaninate; Anabellamide; Asjanin; NSC 306231; Auranamide. Grade: ≥95%. CAS No. 63631-36-7. Molecular formula: C32H30N2O4. Mole weight: 506.59.
Aspersitin
Aspersitin is an antibiotic produced by Aspergillus parasiticus. It has anti-gram-positive and negative bacteria activity. CAS No. 86996-89-6. Molecular formula: C14H21NO4. Mole weight: 267.32.
Aspicilin
It is obtained from the lichens Aspicilia calcarea and A. gibbosa. Synonyms: (-)-Aspicillin; (5R,6S,7R,18S,E)-5,6,7-trihydroxy-18-methyloxacyclooctadec-3-en-2-one; (3E,5R,6S,7R,18S)-5,6,7-Trihydroxy-18-methyloxacyclooctadeca-3-en-2-one; Oxacyclooctadec-3-en-2-one, 5,6,7-trihydroxy-18-methyl-, (3E,5R,6S,7R,18S)-. Grade: 99%. CAS No. 52461-05-9. Molecular formula: C18H32O5. Mole weight: 328.44.
Aspiculamycin
Aspiculamycin is a nucleoside peptide antibiotic produced by Streptomyces toyocaensis var. aspiculamyceticus. It has weak anti-Gram-positive bacteria, negative bacteria, mycobacteria and mycoplasma activity, and has the effect of repelling worms, nematodes and killing worms. Synonyms: Aspiculamycin; Quingfengmycin; Gougerotin. Molecular formula: C19H30O10N8. Mole weight: 530.49.
Aspochalasin D
Aspochalasin D is a potent inhibitor of mammalian tumor cell lines, first isolated from Aspergillus microcysticus. It has antibacterial activity against Gram-positive and Gram-negative bacteria at a concentration of 1 mg/ml. Aspochalasin D was found that it can strongly induce the formation of actin-containing rodlets in the cytoplasm of treated fibroblasts. Synonyms: 1H-Cycloundec(d)isoindole-1,15(2H)-dione, 3,3a,4,6a,9,10,11,12-octahydro-11,12-dihydroxy-4,5,8-trimethyl-3-(2-methylpropyl)-, (3S,3aR,4S,6aS,7E,11R,12S,13E,15aS)-. Grade: ≥95%. CAS No. 71968-02-0. Molecular formula: C24H35NO4. Mole weight: 401.54.
Aspochalasine A
Aspochalasine is an antibiotic produced by Aspergillus microcysticus and an unidentified fungus FA2277. Aspochalasine A has anti-bacterial and fungal activity. Molecular formula: C24H33NO4. Mole weight: 399.52.
Aspochalasine E
Aspochalasine is an antibiotic produced by Aspergillus microcysticus and an unidentified fungus FA2277. Molecular formula: C24H33NO3. Mole weight: 383.52.
Aspochracin
Aspochracin is a cyclic tripeptide isolated from Aspergillus first. Aspochracin is toxic to caught worms (LD50 = 100 μg/g) and silkworms. Grade: >95% by HPLC. CAS No. 22029-09-0. Molecular formula: C23H36N4O4. Mole weight: 432.56.
Astechrome
Astechrome is an antibiotic produced by Aspergillus terreus (IFO 6123). It has weak antibacterial activity. Molecular formula: (C20H22N3O3)3Fe. Mole weight: 1113.09.
Astepyrone
Astepyrone is an antibiotic produced by Aspergillus terreus (IFO 4100). It has anti-ulcer effect. CAS No. 86925-92-0. Molecular formula: C9H12O5. Mole weight: 200.19.
Asterobactin
Asterobactin is a siderophore antibiotic produced by Nocardia asteroides IFM 0959. It has anti-tumor activity and inhibits HL-60 and HeLa cells at a concentration of 0.2-3.2 μg/mL, and Fe3+ can reduce its activity. Synonyms: Asterobactin A. CAS No. 482372-30-5. Molecular formula: C34H55N7O13. Mole weight: 769.84.
Asterric acid
Asterric acid is an Endothelin (ET) binding inhibitor produced by Aspergillus sp. Synonyms: Dimethylosoic acid,TAN 1415A, WF 12880A. Grade: >98%. CAS No. 577-64-0. Molecular formula: C17H16O8. Mole weight: 348.30.
Asterriquinol D dimethyl ether
Asterriquinol D dimethylether is a fungal metabolite first isolated from Aspergillus terreus as part of the asterriquinone complex. It is cytotoxic to NS-1 mouse myeloma cells with IC50 of 28 μg/ml. It has weak activity against tumor cells and the parasitic protozoan, Tritrichomonas foetus. Synonyms: 3,3'-(2,3,5,6-tetramethoxy-1,4-phenylene)bis-1H-indole. Grade: ≥95%. CAS No. 287117-66-2. Molecular formula: C26H24N2O4. Mole weight: 428.48.
Asterriquinone CT1
Asterriquinone CT1 is an asinquinone antibiotic produced by fungi. It has the effect of inhibiting serine protease in the blood mimicking pathway. Molecular formula: C32H26N2O4. Mole weight: 502.56.
Asterriquinone CT2
Asterriquinone CT2 is an asinquinone antibiotic produced by fungi. It has the effect of inhibiting serine protease in the blood mimicking pathway. Molecular formula: C32H28N2O4. Mole weight: 504.57.
Asterriquinone SU5228
Asterriquinone SU5228 is a quinone compounds containing indole produced by Aspergillus candidus. It has the effect of inhibiting the binding of Grb-2 adaptor (Adapter) to phosphorylated epidermal growth factor (EGF) receptor tyrosine kinase. Molecular formula: C27H22N2O4. Mole weight: 438.47.
Asterriquinone SU5500
Asterriquinone SU5500 is a quinone compounds containing indole produced by Aspergillus candidus. It has the effect of inhibiting the binding of Grb-2 adaptor (Adapter) to phosphorylated epidermal growth factor (EGF) receptor tyrosine kinase. Synonyms: 2,5-Bis[2-(3-methyl-2-butenyl)-1H-indole-3-yl]-3-acetoxy-6-hydroxy-1,4-benzoquinone. Molecular formula: C34H32N2O5. Mole weight: 548.64.
Asticolorin A
Asticolorin A is a mycotoxin produced by Aspergillus multicolor MRC 638. CAS No. 93376-70-6. Molecular formula: C33H30O7. Mole weight: 538.59.
Asticolorin B
Asticolorin B is a mycotoxin produced by Aspergillus multicolor MRC 638. CAS No. 93376-71-7. Molecular formula: C33H28O7. Mole weight: 536.57.
Asticolorin C
Asticolorin C is a mycotoxin produced by Aspergillus multicolor MRC 638. CAS No. 93395-44-9. Molecular formula: C33H28O9. Mole weight: 568.57.
Aszonalenin
Aszonalenin is a nitrogen-containing heterocyclic antibiotic produced by Aspergillus zonatus. It can cause abnormal second division of sea urchin embryo. CAS No. 81797-27-5. Molecular formula: C23H23N3O2. Mole weight: 373.45.
Aszonapyrone A
Aszonapyrone A is a lactone antibiotic produced by Aspergillus zonatus, which has anti-Staphylococcus aureus activity. CAS No. 83103-08-6. Molecular formula: C28H40O5. Mole weight: 456.61.
AT 2433 A1
AT 2433 A1 is an anti-tumor antibiotic produced by Actinomadura melliaura. It has activity against gram-positive bacteria. It can prolong the survival period of transplanted leukemia P388 mice. Synonyms: AT2433-A1; 6-Methyl-11-chloro-12-[6-O-[4-(methylamino)-2,4-dideoxy-alpha-L-threo-pentopyranosyl]-4-O-methyl-beta-D-glucopyranosyl]-12,13-dihydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione. Grade: >98%. CAS No. 102644-20-2. Molecular formula: C34H35ClN4O9. Mole weight: 679.11.
AT 2433 A2
AT 2433 A2 is an anti-tumor antibiotic produced by Actinomadura melliaura. It has activity against gram-positive bacteria. Synonyms: AT 2433-A2; AT2433-A2. Grade: >98%. CAS No. 102644-19-9. Molecular formula: C33H33ClN4O9. Mole weight: 665.09.
AT 2433 B1
AT 2433 B1 is an anti-tumor antibiotic produced by Actinomadura melliaura. It has activity against gram-positive bacteria. It can prolong the survival period of transplanted leukemia P388 mice. Synonyms: AT2433-B1. Grade: >98%. CAS No. 102622-96-8. Molecular formula: C34H36N4O9. Mole weight: 644.67.
AT 2433 B2
AT 2433 B2 is an anti-tumor antibiotic produced by Actinomadura melliaura. It has activity against gram-positive bacteria. Synonyms: AT2433-B2; 5H-Indolo(2,3-a)pyrrolo(3,4-c)carbazole-5,7(6H)-dione, 12-(6-O-(4-amino-2,4-dideoxypentopyranosyl)-4-O-methylhexopyranosyl)-12,13-dihydor-6-methyl-. Grade: >98%. CAS No. 102622-95-7. Molecular formula: C33H34N4O9. Mole weight: 630.64.
Atramycin A
Atramycin A is an isotetracenone antitumor antibiotic produced by Streptomyces atratus BY90. It has the activity of inhibiting murine leukemia P388 cells with an ICso of 4.5 μg/mL. CAS No. 137109-48-9. Molecular formula: C25H24O9. Mole weight: 468.45.
Atramycin B
Atramycin B is an Isotetracenone antitumor antibiotic produced by Streptomyces atratus BY90. It has the activity of inhibiting murine leukemia P388 cells with an ICso of 9.8 μg/mL. CAS No. 137109-49-0. Molecular formula: C25H24O8. Mole weight: 452.45.
Atrovenetin
Atrovenetin is an antibiotic produced by Penicillum herquei PRL 1838 and Pen. atrovenetum SM 683. Molecular formula: C19H18O6. Mole weight: 342.34.
Aurachin C
Aurachin C is a quinoline compound produced by Stigmatella aurantiaca Sg al5. It has the activity of inhibiting gram-positive bacteria and a few yeasts and filamentous fungi, and can block the NADH oxidation of bovine heart microsomal particles. CAS No. 108354-14-9. Molecular formula: C25H33NO2. Mole weight: 379.53.
Aurachin D
Aurachin D is a quinoline compound produced by Stigmatella aurantiaca Sg al5. It has the activity of inhibiting gram-positive bacteria and a few yeasts and filamentous fungi, and can block the NADH oxidation of bovine heart microsomal particles. CAS No. 108354-13-8. Molecular formula: C25H33NO. Mole weight: 363.53.
Aurantimycin A
Aurantimycin A is an antibiotic isolated from Streptomyces aurantiacus IMET 43917. Aurantimycin A has activity against Gram-positive bacteria and inhibits cell adhesion. Synonyms: Aurantimycin; NSC-777195; D-Alanine, (3S)-3-hydroxy-N-[(2R)-2-hydroxy-1-oxo-2-[(2S,5S,6S)-tetrahydro-2-hydroxy-6-methyl-5-(2-methylpropyl)-2H-pyran-2-yl]propyl]-L-leucyl-(3R)-hexahydro-3-pyridazinecarbonyl-N-hydroxy-O-methyl-L-serylglycyl-(3S)-hexahydro-3-pyridazinecarbonyl-N-hydroxy-, (6→13)-lactone. Grade: ≥95%. CAS No. 162478-50-4. Molecular formula: C38H64N8O14. Mole weight: 856.96.
Aurantimycinn A
Aurantimycinn A is produced by the strain of Streptomyces aurantiacus IMET 43917. Aurantimycinn A has strong anti-gram positive bacterial activity, with MIC 0.007-0.08μg/mL, which can be tolerated by mice 1mg/kg (intravenous), 250mg/kg (oral). Molecular formula: C38H64N8O14. Mole weight: 856.96.
Aurantimycinn B
Aurantimycinn B is produced by the strain of Streptomyces aurantiacus IMET 43917. Aurantimycinn B has the activity of anti-gram positive bacterial, twice to four times lower than Aurantimycinn A. Molecular formula: C38H62N8O14. Mole weight: 854.94.
Aurantimycinn C
Aurantimycinn C is produced by the strain of Streptomyces aurantiacus IMET 43917. Aurantimycinn C has the activity of anti-gram positive bacterial, twice to four times lower than Aurantimycinn A. Molecular formula: C38H60N8O14. Mole weight: 852.93.
Aureobasidine A
Aureobasidine A is produced by the strain of Aureobasidium pullulans R106. A has strong activity against candida albicans, Cryptococcus neoformans, budding yeast, histocapsular clinophyte and other pathogenic fungi, and its activity exceeds that of amphotericin B in most cases. The effect on candidiasis is bactericidal, and the therapeutic effect on systemic candidiasis in mice is superior to fluconum and amphotericin B. Molecular formula: C60H92N8O11. Mole weight: 1101.42.
Aureoquinone
Aureoquinone is produced by the strain of Aureobasidium sp. The IC50 (μg/mL) for inhibiting the activity of protease, including trypsin, papain, thermophilic protease, collagenase and pound-protease are 11.4, 14.5, 17.8, 7.1, and 8.7 respectively. Synonyms: 2,5,7,8-tetrahydroxy-3,6-dimethylnaphthalene-1,4-dione. Molecular formula: C12H10O6. Mole weight: 250.20.
Aureusimine B
It is an inhibitor of the protease Calpain produced by the strain of Streptomyces sp. SC433. It is a small molecular weight monoketopiperazine formed non-ribosomally by the fusion of phenylalanine and valin. Synonyms: Phevalin; 3-(1-Methylethyl)-6-(phenylmethyl)-2(1H)-pyrazinone; 6-Benzyl-3-isopropylpyrazin-2-one. Grade: >95% by HPLC. CAS No. 170713-71-0. Molecular formula: C14H16N2O. Mole weight: 228.29.
Auroglaucin
It is produced by the strain of Aspergillus spp. Synonyms: 2-[(1E,3E,5E)-1,3,5-Heptatrienyl]-3,6-dihydroxy-5-(3-methyl-2-butenyl)benzaldehyde; Auroglaucine; 2-((1E,3E,5E)-hepta-1,3,5-trien-1-yl)-3,6-dihydroxy-5-(3-methylbut-2-en-1-yl)benzaldehyde. CAS No. 41451-81-4. Molecular formula: C19H22O3. Mole weight: 298.38.
Australifungin
Australifungin is produced by the strain of Sporormiella australis. As an inhibitor of Shinganine n-acyl-transferase, it has strong antifungal activity, with MIC of 0.015-0.5 μg/mL for candida, cryptococcus neoforme, saccharomyces cerescens and other fungi, and 0.125 ~ 1μg/ mL for aspergillus. Australian fennetol has a low antifungal effect. Molecular formula: C23H36O6. Mole weight: 408.53.
Averantin
Averantin is an anthraquinone fungal metabolite produced by Aspergillus sp. associated with Panax notoginseng. It is a mycotoxic intermediate in the pathway to aflatoxin B1. It displays antifungal activity against Fusariumsolani (pathogenic fungus of P. notoginseng) with minimum inhibitory concentrations of 16-32 ug/mL. It also shows antibacterial activity against Bacillus subtilis with minimum inhibitory concentrations of 16-32 ug/mL. Synonyms: 1,3,6,8-Tetrahydroxy-2-[(1S)-1-hydroxyhexyl]-9,10-anthracenedione; (-)-Averantin; (S)-1,3,6,8-Tetrahydroxy-2-(1-hydroxyhexyl)-9,10-anthracenedione; 9,10-Anthracenedione, 1,3,6,8-tetrahydroxy-2-[(1S)-1-hydroxyhexyl]-; (1'S)-averantin; (S)-(-)-averantin; (S)-averantin. Grade: ≥95%. CAS No. 5803-62-3. Molecular formula: C20H20O7. Mole weight: 372.37.
Avermectin A1a
Avermectin A1a is produced by the strain of Streptomyces avermitilis. It stimulates nerve cells to release Y-aminobutyric acid (GABA), which blocks the transmission of signals from the central nervous system to the motor nerve. It is not resistant to bacteria and fungi, but has strong activity to nematode parasites such as ancylostoma and Pteria, as well as insects such as flies. Abamectin B1a has the highest activity. Ivermectin obtained by catalytic hydrogenation contains 22 23- dihydroabamectin B1a (above 80%) and 22 23 dioxabamectin B1b (below 20%). Less active than B1a but less toxic. Used as repellent (subcutaneous or oral) for cattle, sheep and pigs, it is also effective against human filariasis. Synonyms: SCHEMBL1681257. CAS No. 65195-51-9. Molecular formula: C49H74O14. Mole weight: 887.10.
Avermectin B1a aglycone
It is an acid degradation product produced by hydrolysis of the disaccharide unit of avermectin. It is an inhibitor of nematode larval development. It has no paralytic activity. It is an anthelmintic in animal health. Synonyms: (6R,13S,25R)-22,23-didehydro-5-O-demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-[(1S)-1-methylpropyl]-milbemycin B. Grade: >95% by HPLC. CAS No. 71828-14-3. Molecular formula: C34H48O8. Mole weight: 584.74.
Avermectin B1a monosaccharide
It is an acid degradation product produced by selective hydrolysis of the terminal saccharide unit of avermectin. It is a potent inhibitor of nematode larval development. It has no paralytic activity. Synonyms: 4'-O-de(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-5-O-demethyl-avermectin A1a; 5-O-Demethyl-4'-O-de(2,6-dideoxy-3-O-methyl-α-L-glucopyranosyl)avermectin A1a; MSB 1a. Grade: >95% by HPLC. CAS No. 71831-09-9. Molecular formula: C41H60O11. Mole weight: 728.91.
Averufin
Averufin is produced by the strain of Asergillus sp. Ames tests showed a weak mutagenic effect. Synonyms: Averufine; 3,4,5,6-Tetrahydro-7,9,11-trihydroxy-2-methyl-2,6-epoxy-2H-anthra[2,3-b]oxocin-8,13-dione. CAS No. 14016-29-6. Molecular formula: C20H16O7. Mole weight: 368.34.
Avidinorubicin
Avidinorubicin is produced by the strain of Streptomyces avidinii. It has anti-gram positive and negative bacterial activity, and has cytotoxicity to tumor cells. Molecular formula: C60H86N4O22. Mole weight: 1215.34.
Avrainvillamide
Avrainvillamide is a fungal metabolite and monomeric form of stephacidin B that has been found in A. ochraceus. It is active against S. aureus, S. pyogenes, and E. faecalis (MICs = 12.5, 12.5, and 25 μg/ml, respectively). Avrainvillamide inhibits the growth of LNCaP, BT-549, T47D, and MALME-3M cancer cells with GI50 values of 0.24, 0.62, 0.21, and 0.41 μM, respectively. Synonyms: CJ-17,665; CJ17,665; CJ 17,665; 3,11,12,13,13aS,14-hexahydro-3,3,14,14-tetramethyl-8H,10H-7aS,12aS-(iminomethano)indolizino[6,7-h]pyrano[3,2-a]carbazole-8,16-dione 15-oxide. Grade: >95% by HPLC. CAS No. 269741-97-1. Molecular formula: C26H27N3O4. Mole weight: 445.52.