BOC Sciences 12 - Products

BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.

Product
Asparaginyl-lysine Asparaginyl-Lysine is a dipeptide composed of asparagine and lysine. Synonyms: Asn-Lys; NK dipeptide. CAS No. 22677-58-3. Molecular formula: C10H20N4O4. Mole weight: 260.29. BOC Sciences 12
Asparaginyl-phenylalanine Asparaginyl-Phenylalanine is a dipeptide composed of asparagine and phenylalanine. Synonyms: L-Asparaginyl-L-phenylalanine; Asn-Phe. CAS No. 22849-01-0. Molecular formula: C13H17N3O4. Mole weight: 279.29. BOC Sciences 12
Asparaginyl-proline Asparaginyl-proline is a dipeptide composed of asparagine and proline. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: L-Proline, 1-L-asparaginyl-; H-NP-OH; L-asparagyl-L-proline; Asn-Pro; L-Asn-L-Pro. Grade: ≥95%. CAS No. 78346-95-9. Molecular formula: C9H15N3O4. Mole weight: 229.23. BOC Sciences 12
Asparaginyl-serine Asparaginyl-serine is a dipeptide composed of asparagine and serine. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: L-Serine, L-asparaginyl-; Asn-Ser; L-Asn-L-Ser; L-Asparaginyl-L-serine; H-NS-OH; Asparaginylserine. Grade: ≥95%. CAS No. 92172-15-1. Molecular formula: C7H13N3O5. Mole weight: 219.20. BOC Sciences 12
Asparaginyl-tryptophan Asparaginyl-tryptophan is a dipeptide composed of asparagine and tryptophan. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: L-Tryptophan, L-asparaginyl-; H-NW-OH; L-asparagyl-L-tryptophan; Asn-Trp; Asparaginyltryptophan; L-Tryptophan, N-L-asparaginyl-. Grade: ≥95%. CAS No. 74105-03-6. Molecular formula: C15H18N4O4. Mole weight: 318.33. BOC Sciences 12
Asparenomycin A Asparenomycin A is a carbapenem antibiotic produced by Streptomyces tokunonensis sp. (PA-31088) and Srt.argenteolus (PA-39504). It has anti-gram-positive and negative bacteria activity, can inhibit a variety of β-lactamases, and also has an effect on β-lactamase-producing strains. Synonyms: Asparenomycin. CAS No. 76466-24-5. Molecular formula: C14H16N2O6S. Mole weight: 340.35. BOC Sciences 12
Asparenomycin B Asparenomycin B is a carbapenem antibiotic produced by Streptomyces tokunonensis sp. (PA-31088) and Srt.argenteolus (PA-39504). It has anti-gram-positive and negative bacteria activity, can inhibit a variety of β-lactamases, and also has an effect on β-lactamase-producing strains. CAS No. 79366-72-6. Molecular formula: C14H18N2O6S. Mole weight: 342.37. BOC Sciences 12
Asparenomycin C Asparenomycin C is a carbapenem antibiotic produced by Streptomyces tokunonensis sp. (PA-31088) and Srt.argenteolus (PA-39504). It has anti-gram-positive and negative bacteria activity, can inhibit a variety of β-lactamases, and also has an effect on β-lactamase-producing strains. CAS No. 81018-71-5. Molecular formula: C14H16N2O5S. Mole weight: 324.35. BOC Sciences 12
Aspartyl-arginine Aspartyl-arginine. Synonyms: Aspartate Arginine dipeptide. Molecular formula: C10H19N5O5. Mole weight: 289.29. BOC Sciences 12
Aspartyl-asparagine Aspartyl-asparagine. Synonyms: L-α-Aspartyl-L-asparagine. CAS No. 13433-11-9. Molecular formula: C8H13N3O6. Mole weight: 247.21. BOC Sciences 12
Aspartyl-histidine Aspartyl-Histidine is a dipeptide composed of aspartate and histidine. Synonyms: Asp-His; L-alpha-aspartyl-L-histidine. CAS No. 22677-56-1. Molecular formula: C10H14N4O5. Mole weight: 270.24. BOC Sciences 12
Aspartyl-isoleucine Aspartyl-isoleucine. Synonyms: alpha-Asp-Ile; L-Aspartyl-L-Isoleucine; L-alpha-aspartyl-L-isoleucine. CAS No. 13433-07-3. Molecular formula: C10H18N2O5. Mole weight: 246.26. BOC Sciences 12
Aspartyl-serine Aspartyl-serine is a dipeptide composed of aspartic acid and serine. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: L-Serine, L-a-aspartyl-; Aspartylserine; (S)-3-Amino-N-((S)-1-carboxy-2-hydroxy-ethyl)-succinamic acid; Asp-Ser; α-L-Asparagyl-L-serine; L-Asp-L-Ser; H-DS-OH; L-alpha-aspartyl-L-serine; (S)-3-amino-4-(((S)-1-carboxy-2-hydroxyethyl)amino)-4-oxobutanoic acid. Grade: ≥95%. CAS No. 6403-13-0. Molecular formula: C7H12N2O6. Mole weight: 220.18. BOC Sciences 12
Aspartyl-threonine Aspartyl-Threonine is a dipeptide composed of aspartate and threonine. Synonyms: aspartylthreonine; Asp-Thr; DT dipeptide; D-T Dipeptide. CAS No. 13433-17-5. Molecular formula: C8H14N2O6. Mole weight: 234.21. BOC Sciences 12
Asperaldin Asperaldin is an aldose reductase (ECLLL21) inhibitor produced by Aspergillus niger CFR-1046. Synonyms: 1,4-Naphthalenedione, 8-(hexyloxy)-2,6-dihydroxy-. CAS No. 561297-46-9. Molecular formula: C16H18O5. Mole weight: 290.31. BOC Sciences 12
Aspercolorin An atypical cyclic tetrapeptide in which one of the amino acids is a 5-methoxyanthranilic acid. Aspercolorin is a fungal metabolite produced by Aspergillus versicolor. It is used as a secondary metabolite standard in polyphasic taxonomy for the identification of aspergillus versicolor. Synonyms: 1,2,3,5,6,7,8,9,10,11,12,17,18,18a-Tetradecahydro-10-benzyl-14-methoxypyrrolo[1,2-a][1,4,8,11]benzotetraazacyclotetradecine-5,9,12,18-tetrone; 10-benzyl-14-methoxy-1,2,3,7,8,10,11,18a-octahydrobenzo[e]pyrrolo[1,2-a][1,4,8,11]tetraazacyclotetradecine-5,9,12,18(6H,17H)-tetraone; Cyclo(β-alanylprolyl-2-amino-5-methoxybenzoylphenylalanyl). Grade: >97% by HPLC. CAS No. 29123-52-2. Molecular formula: C25H28N4O5. Mole weight: 464.51. BOC Sciences 12
Aspergillic acid Aspergillic acid is an antibiotic produced by Aspergillus flavus. Aspergillic acid has anti-gram-positive bacteria, gram-negative bacteria, mycobacteria and Candida albicans activities. Synonyms: 3-Isobutyl-6-sec-butyl-2-hydroxypyrazine 1-oxide. CAS No. 490-02-8. Molecular formula: C12H20N2O2. Mole weight: 224.30. BOC Sciences 12
Aspergillimide Aspergillimide is a product produced by Aspergillus sp. IMI 337664 with anthelmintic effect. Synonyms: Asperparaline A; (1R,3'R,5aR,8aR,9aS)-rel-(-)-tetrahydro-1,1',8,8,11-pentamethyl-spiro[5H,6H-5a,9a-(iminomethano)-1H-cyclopent[f]indolizine-7(8H),3'-pyrrolidine]-2',5',10-trione; VM 55598; Antibiotic VM 55598. Grade: >98%. CAS No. 195966-93-9. Molecular formula: C20H29N3O3. Mole weight: 359.46. BOC Sciences 12
Aspergillin PZ Asperillin PZ is an isoindole fungal metabolite produced by Aspergillus awamoli. 0.089 μmol/L can cause the morphological changes of the conidia of Pear spores. It may possess anti-cancer and anti-tumor properties. Synonyms: (1R,2S,5R,5aS,5bS,8R,8aS,9R,11aR,13aR)-2,3,4,5,5a,5b,8,8a,9,10,13,13a-Dodecahydro-2-hydroxy-5,7,8-trimethyl-9-(2-methylpropyl)-1,5-epoxy-1H-cyclohepta[3,4]benz[1,2-d]isoindole-11,12-dione; (+)-Aspergillin PZ; Aspergilline PZ. Grade: >98%. CAS No. 483305-08-4. Molecular formula: C24H35NO4. Mole weight: 401.54. BOC Sciences 12
Aspergillumarin Aspergillus A is a dihydroisocoumarin derivative isolated from the culture broth of the marine-derived fungus Aspergillus. CAS No. 1392495-06-5. Molecular formula: C14H16O4. Mole weight: 248.27. BOC Sciences 12
Aspergin Aspergin is an antibiotic produced by Aspergillus sp., with activity against gram-positive bacteria. CAS No. 40434-07-9. Molecular formula: C19H26O3. Mole weight: 302.41. BOC Sciences 12
Asperlactone Asperlactone is a biologically active polyketide metabolite produced mainly from Aspergillus westerdijkiae. Asperlactone is a nematicidal, an insecticidal, an antibacterial and an antifungal agent. Synonyms: 2(5H)-Furanone, 5-((1S)-1-hydroxyethyl)-3-((2S,3S)-3-methyloxiranyl)-, (5R)-; [2S-[2α[S*(R*)],3β]]-5-(1-hydroxyethyl)-3-(3-methyloxiranyl)-2(5H)-furanone. Grade: ≥98%. CAS No. 76375-62-7. Molecular formula: C9H12O4. Mole weight: 184.19. BOC Sciences 12
Asperlicin Asperlicin is a non-peptide cholecystokinin (Cholecystokinin, CCK) produced by Aspergillus alliaceus. It has the effect of antagonizing CCK. A and its derivatives are promising for the treatment of ulcers and pancreatic tumors. Synonyms: Asperlicin A. CAS No. 93413-04-8. Molecular formula: C31H29N5O4. Mole weight: 535.59. BOC Sciences 12
Asperphenamate Asperphenamate is a fungal secondary metabolite isolated from Aspergillus flavipes. Asperphenamate has been found in a broad range of Pencillium and Aspergillus species and even in plants, as a product of endophytic fungi. Asperphenamate has weak antitumor activity. It inhibits proliferation of T47D and MDA-MB-231 breast and HL-60 leukemia cancer cell lines (IC50s = 92.3, 96.5, and 97.9 μM, respectively) and inhibits yeast α-glucosidase activity (IC50 = 8.3 μM). Asperphenamate is also used to synthesize N-Benzoyl-O-(N'-(1-benzyloxycarbonyl-4-piperidiylcarbonyl)-D-phenylalanyl)-D-phenylalaninol (BBP), an asperphenamate derivative that inhibits human breast carcinoma MCF-7 cell growth. Synonyms: (S)-N-Benzoyl-L-phenylalanine 2-(Benzoylamino)-3-phenylpropyl Ester; N-Benzoyl-phenylalanine 2-benzoylamino-3-phenylpropyl Ester; N-Benzoyl-L-phenylalaninol N-benzoyl-L-phenylalaninate; Anabellamide; Asjanin; NSC 306231; Auranamide. Grade: ≥95%. CAS No. 63631-36-7. Molecular formula: C32H30N2O4. Mole weight: 506.59. BOC Sciences 12
Aspersitin Aspersitin is an antibiotic produced by Aspergillus parasiticus. It has anti-gram-positive and negative bacteria activity. CAS No. 86996-89-6. Molecular formula: C14H21NO4. Mole weight: 267.32. BOC Sciences 12
Aspicilin It is obtained from the lichens Aspicilia calcarea and A. gibbosa. Synonyms: (-)-Aspicillin; (5R,6S,7R,18S,E)-5,6,7-trihydroxy-18-methyloxacyclooctadec-3-en-2-one; (3E,5R,6S,7R,18S)-5,6,7-Trihydroxy-18-methyloxacyclooctadeca-3-en-2-one; Oxacyclooctadec-3-en-2-one, 5,6,7-trihydroxy-18-methyl-, (3E,5R,6S,7R,18S)-. Grade: 99%. CAS No. 52461-05-9. Molecular formula: C18H32O5. Mole weight: 328.44. BOC Sciences 12
Aspiculamycin Aspiculamycin is a nucleoside peptide antibiotic produced by Streptomyces toyocaensis var. aspiculamyceticus. It has weak anti-Gram-positive bacteria, negative bacteria, mycobacteria and mycoplasma activity, and has the effect of repelling worms, nematodes and killing worms. Synonyms: Aspiculamycin; Quingfengmycin; Gougerotin. Molecular formula: C19H30O10N8. Mole weight: 530.49. BOC Sciences 12
Aspochalasin D Aspochalasin D is a potent inhibitor of mammalian tumor cell lines, first isolated from Aspergillus microcysticus. It has antibacterial activity against Gram-positive and Gram-negative bacteria at a concentration of 1 mg/ml. Aspochalasin D was found that it can strongly induce the formation of actin-containing rodlets in the cytoplasm of treated fibroblasts. Synonyms: 1H-Cycloundec(d)isoindole-1,15(2H)-dione, 3,3a,4,6a,9,10,11,12-octahydro-11,12-dihydroxy-4,5,8-trimethyl-3-(2-methylpropyl)-, (3S,3aR,4S,6aS,7E,11R,12S,13E,15aS)-. Grade: ≥95%. CAS No. 71968-02-0. Molecular formula: C24H35NO4. Mole weight: 401.54. BOC Sciences 12
Aspochalasine A Aspochalasine is an antibiotic produced by Aspergillus microcysticus and an unidentified fungus FA2277. Aspochalasine A has anti-bacterial and fungal activity. Molecular formula: C24H33NO4. Mole weight: 399.52. BOC Sciences 12
Aspochalasine E Aspochalasine is an antibiotic produced by Aspergillus microcysticus and an unidentified fungus FA2277. Molecular formula: C24H33NO3. Mole weight: 383.52. BOC Sciences 12
Aspochracin Aspochracin is a cyclic tripeptide isolated from Aspergillus first. Aspochracin is toxic to caught worms (LD50 = 100 μg/g) and silkworms. Grade: >95% by HPLC. CAS No. 22029-09-0. Molecular formula: C23H36N4O4. Mole weight: 432.56. BOC Sciences 12
Astechrome Astechrome is an antibiotic produced by Aspergillus terreus (IFO 6123). It has weak antibacterial activity. Molecular formula: (C20H22N3O3)3Fe. Mole weight: 1113.09. BOC Sciences 12
Astepyrone Astepyrone is an antibiotic produced by Aspergillus terreus (IFO 4100). It has anti-ulcer effect. CAS No. 86925-92-0. Molecular formula: C9H12O5. Mole weight: 200.19. BOC Sciences 12
Asterobactin Asterobactin is a siderophore antibiotic produced by Nocardia asteroides IFM 0959. It has anti-tumor activity and inhibits HL-60 and HeLa cells at a concentration of 0.2-3.2 μg/mL, and Fe3+ can reduce its activity. Synonyms: Asterobactin A. CAS No. 482372-30-5. Molecular formula: C34H55N7O13. Mole weight: 769.84. BOC Sciences 12
Asterric acid Asterric acid is an Endothelin (ET) binding inhibitor produced by Aspergillus sp. Synonyms: Dimethylosoic acid,TAN 1415A, WF 12880A. Grade: >98%. CAS No. 577-64-0. Molecular formula: C17H16O8. Mole weight: 348.30. BOC Sciences 12
Asterriquinol D dimethyl ether Asterriquinol D dimethylether is a fungal metabolite first isolated from Aspergillus terreus as part of the asterriquinone complex. It is cytotoxic to NS-1 mouse myeloma cells with IC50 of 28 μg/ml. It has weak activity against tumor cells and the parasitic protozoan, Tritrichomonas foetus. Synonyms: 3,3'-(2,3,5,6-tetramethoxy-1,4-phenylene)bis-1H-indole. Grade: ≥95%. CAS No. 287117-66-2. Molecular formula: C26H24N2O4. Mole weight: 428.48. BOC Sciences 12
Asterriquinone CT1 Asterriquinone CT1 is an asinquinone antibiotic produced by fungi. It has the effect of inhibiting serine protease in the blood mimicking pathway. Molecular formula: C32H26N2O4. Mole weight: 502.56. BOC Sciences 12
Asterriquinone CT2 Asterriquinone CT2 is an asinquinone antibiotic produced by fungi. It has the effect of inhibiting serine protease in the blood mimicking pathway. Molecular formula: C32H28N2O4. Mole weight: 504.57. BOC Sciences 12
Asterriquinone SU5228 Asterriquinone SU5228 is a quinone compounds containing indole produced by Aspergillus candidus. It has the effect of inhibiting the binding of Grb-2 adaptor (Adapter) to phosphorylated epidermal growth factor (EGF) receptor tyrosine kinase. Molecular formula: C27H22N2O4. Mole weight: 438.47. BOC Sciences 12
Asterriquinone SU5500 Asterriquinone SU5500 is a quinone compounds containing indole produced by Aspergillus candidus. It has the effect of inhibiting the binding of Grb-2 adaptor (Adapter) to phosphorylated epidermal growth factor (EGF) receptor tyrosine kinase. Synonyms: 2,5-Bis[2-(3-methyl-2-butenyl)-1H-indole-3-yl]-3-acetoxy-6-hydroxy-1,4-benzoquinone. Molecular formula: C34H32N2O5. Mole weight: 548.64. BOC Sciences 12
Asticolorin A Asticolorin A is a mycotoxin produced by Aspergillus multicolor MRC 638. CAS No. 93376-70-6. Molecular formula: C33H30O7. Mole weight: 538.59. BOC Sciences 12
Asticolorin B Asticolorin B is a mycotoxin produced by Aspergillus multicolor MRC 638. CAS No. 93376-71-7. Molecular formula: C33H28O7. Mole weight: 536.57. BOC Sciences 12
Asticolorin C Asticolorin C is a mycotoxin produced by Aspergillus multicolor MRC 638. CAS No. 93395-44-9. Molecular formula: C33H28O9. Mole weight: 568.57. BOC Sciences 12
Aszonalenin Aszonalenin is a nitrogen-containing heterocyclic antibiotic produced by Aspergillus zonatus. It can cause abnormal second division of sea urchin embryo. CAS No. 81797-27-5. Molecular formula: C23H23N3O2. Mole weight: 373.45. BOC Sciences 12
Aszonapyrone A Aszonapyrone A is a lactone antibiotic produced by Aspergillus zonatus, which has anti-Staphylococcus aureus activity. CAS No. 83103-08-6. Molecular formula: C28H40O5. Mole weight: 456.61. BOC Sciences 12
AT 2433 A1 AT 2433 A1 is an anti-tumor antibiotic produced by Actinomadura melliaura. It has activity against gram-positive bacteria. It can prolong the survival period of transplanted leukemia P388 mice. Synonyms: AT2433-A1; 6-Methyl-11-chloro-12-[6-O-[4-(methylamino)-2,4-dideoxy-alpha-L-threo-pentopyranosyl]-4-O-methyl-beta-D-glucopyranosyl]-12,13-dihydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione. Grade: >98%. CAS No. 102644-20-2. Molecular formula: C34H35ClN4O9. Mole weight: 679.11. BOC Sciences 12
AT 2433 A2 AT 2433 A2 is an anti-tumor antibiotic produced by Actinomadura melliaura. It has activity against gram-positive bacteria. Synonyms: AT 2433-A2; AT2433-A2. Grade: >98%. CAS No. 102644-19-9. Molecular formula: C33H33ClN4O9. Mole weight: 665.09. BOC Sciences 12
AT 2433 B1 AT 2433 B1 is an anti-tumor antibiotic produced by Actinomadura melliaura. It has activity against gram-positive bacteria. It can prolong the survival period of transplanted leukemia P388 mice. Synonyms: AT2433-B1. Grade: >98%. CAS No. 102622-96-8. Molecular formula: C34H36N4O9. Mole weight: 644.67. BOC Sciences 12
AT 2433 B2 AT 2433 B2 is an anti-tumor antibiotic produced by Actinomadura melliaura. It has activity against gram-positive bacteria. Synonyms: AT2433-B2; 5H-Indolo(2,3-a)pyrrolo(3,4-c)carbazole-5,7(6H)-dione, 12-(6-O-(4-amino-2,4-dideoxypentopyranosyl)-4-O-methylhexopyranosyl)-12,13-dihydor-6-methyl-. Grade: >98%. CAS No. 102622-95-7. Molecular formula: C33H34N4O9. Mole weight: 630.64. BOC Sciences 12
Atramycin A Atramycin A is an isotetracenone antitumor antibiotic produced by Streptomyces atratus BY90. It has the activity of inhibiting murine leukemia P388 cells with an ICso of 4.5 μg/mL. CAS No. 137109-48-9. Molecular formula: C25H24O9. Mole weight: 468.45. BOC Sciences 12
Atramycin B Atramycin B is an Isotetracenone antitumor antibiotic produced by Streptomyces atratus BY90. It has the activity of inhibiting murine leukemia P388 cells with an ICso of 9.8 μg/mL. CAS No. 137109-49-0. Molecular formula: C25H24O8. Mole weight: 452.45. BOC Sciences 12
Atrovenetin Atrovenetin is an antibiotic produced by Penicillum herquei PRL 1838 and Pen. atrovenetum SM 683. Molecular formula: C19H18O6. Mole weight: 342.34. BOC Sciences 12
Aurachin C Aurachin C is a quinoline compound produced by Stigmatella aurantiaca Sg al5. It has the activity of inhibiting gram-positive bacteria and a few yeasts and filamentous fungi, and can block the NADH oxidation of bovine heart microsomal particles. CAS No. 108354-14-9. Molecular formula: C25H33NO2. Mole weight: 379.53. BOC Sciences 12
Aurachin D Aurachin D is a quinoline compound produced by Stigmatella aurantiaca Sg al5. It has the activity of inhibiting gram-positive bacteria and a few yeasts and filamentous fungi, and can block the NADH oxidation of bovine heart microsomal particles. CAS No. 108354-13-8. Molecular formula: C25H33NO. Mole weight: 363.53. BOC Sciences 12
Aurantimycin A Aurantimycin A is an antibiotic isolated from Streptomyces aurantiacus IMET 43917. Aurantimycin A has activity against Gram-positive bacteria and inhibits cell adhesion. Synonyms: Aurantimycin; NSC-777195; D-Alanine, (3S)-3-hydroxy-N-[(2R)-2-hydroxy-1-oxo-2-[(2S,5S,6S)-tetrahydro-2-hydroxy-6-methyl-5-(2-methylpropyl)-2H-pyran-2-yl]propyl]-L-leucyl-(3R)-hexahydro-3-pyridazinecarbonyl-N-hydroxy-O-methyl-L-serylglycyl-(3S)-hexahydro-3-pyridazinecarbonyl-N-hydroxy-, (6→13)-lactone. Grade: ≥95%. CAS No. 162478-50-4. Molecular formula: C38H64N8O14. Mole weight: 856.96. BOC Sciences 12
Aurantimycinn A Aurantimycinn A is produced by the strain of Streptomyces aurantiacus IMET 43917. Aurantimycinn A has strong anti-gram positive bacterial activity, with MIC 0.007-0.08μg/mL, which can be tolerated by mice 1mg/kg (intravenous), 250mg/kg (oral). Molecular formula: C38H64N8O14. Mole weight: 856.96. BOC Sciences 12
Aurantimycinn B Aurantimycinn B is produced by the strain of Streptomyces aurantiacus IMET 43917. Aurantimycinn B has the activity of anti-gram positive bacterial, twice to four times lower than Aurantimycinn A. Molecular formula: C38H62N8O14. Mole weight: 854.94. BOC Sciences 12
Aurantimycinn C Aurantimycinn C is produced by the strain of Streptomyces aurantiacus IMET 43917. Aurantimycinn C has the activity of anti-gram positive bacterial, twice to four times lower than Aurantimycinn A. Molecular formula: C38H60N8O14. Mole weight: 852.93. BOC Sciences 12
Aureobasidine A Aureobasidine A is produced by the strain of Aureobasidium pullulans R106. A has strong activity against candida albicans, Cryptococcus neoformans, budding yeast, histocapsular clinophyte and other pathogenic fungi, and its activity exceeds that of amphotericin B in most cases. The effect on candidiasis is bactericidal, and the therapeutic effect on systemic candidiasis in mice is superior to fluconum and amphotericin B. Molecular formula: C60H92N8O11. Mole weight: 1101.42. BOC Sciences 12
Aureoquinone Aureoquinone is produced by the strain of Aureobasidium sp. The IC50 (μg/mL) for inhibiting the activity of protease, including trypsin, papain, thermophilic protease, collagenase and pound-protease are 11.4, 14.5, 17.8, 7.1, and 8.7 respectively. Synonyms: 2,5,7,8-tetrahydroxy-3,6-dimethylnaphthalene-1,4-dione. Molecular formula: C12H10O6. Mole weight: 250.20. BOC Sciences 12
Aureusimine B It is an inhibitor of the protease Calpain produced by the strain of Streptomyces sp. SC433. It is a small molecular weight monoketopiperazine formed non-ribosomally by the fusion of phenylalanine and valin. Synonyms: Phevalin; 3-(1-Methylethyl)-6-(phenylmethyl)-2(1H)-pyrazinone; 6-Benzyl-3-isopropylpyrazin-2-one. Grade: >95% by HPLC. CAS No. 170713-71-0. Molecular formula: C14H16N2O. Mole weight: 228.29. BOC Sciences 12
Auroglaucin It is produced by the strain of Aspergillus spp. Synonyms: 2-[(1E,3E,5E)-1,3,5-Heptatrienyl]-3,6-dihydroxy-5-(3-methyl-2-butenyl)benzaldehyde; Auroglaucine; 2-((1E,3E,5E)-hepta-1,3,5-trien-1-yl)-3,6-dihydroxy-5-(3-methylbut-2-en-1-yl)benzaldehyde. CAS No. 41451-81-4. Molecular formula: C19H22O3. Mole weight: 298.38. BOC Sciences 12
Australifungin Australifungin is produced by the strain of Sporormiella australis. As an inhibitor of Shinganine n-acyl-transferase, it has strong antifungal activity, with MIC of 0.015-0.5 μg/mL for candida, cryptococcus neoforme, saccharomyces cerescens and other fungi, and 0.125 ~ 1μg/ mL for aspergillus. Australian fennetol has a low antifungal effect. Molecular formula: C23H36O6. Mole weight: 408.53. BOC Sciences 12
Averantin Averantin is an anthraquinone fungal metabolite produced by Aspergillus sp. associated with Panax notoginseng. It is a mycotoxic intermediate in the pathway to aflatoxin B1. It displays antifungal activity against Fusariumsolani (pathogenic fungus of P. notoginseng) with minimum inhibitory concentrations of 16-32 ug/mL. It also shows antibacterial activity against Bacillus subtilis with minimum inhibitory concentrations of 16-32 ug/mL. Synonyms: 1,3,6,8-Tetrahydroxy-2-[(1S)-1-hydroxyhexyl]-9,10-anthracenedione; (-)-Averantin; (S)-1,3,6,8-Tetrahydroxy-2-(1-hydroxyhexyl)-9,10-anthracenedione; 9,10-Anthracenedione, 1,3,6,8-tetrahydroxy-2-[(1S)-1-hydroxyhexyl]-; (1'S)-averantin; (S)-(-)-averantin; (S)-averantin. Grade: ≥95%. CAS No. 5803-62-3. Molecular formula: C20H20O7. Mole weight: 372.37. BOC Sciences 12
Avermectin A1a Avermectin A1a is produced by the strain of Streptomyces avermitilis. It stimulates nerve cells to release Y-aminobutyric acid (GABA), which blocks the transmission of signals from the central nervous system to the motor nerve. It is not resistant to bacteria and fungi, but has strong activity to nematode parasites such as ancylostoma and Pteria, as well as insects such as flies. Abamectin B1a has the highest activity. Ivermectin obtained by catalytic hydrogenation contains 22 23- dihydroabamectin B1a (above 80%) and 22 23 dioxabamectin B1b (below 20%). Less active than B1a but less toxic. Used as repellent (subcutaneous or oral) for cattle, sheep and pigs, it is also effective against human filariasis. Synonyms: SCHEMBL1681257. CAS No. 65195-51-9. Molecular formula: C49H74O14. Mole weight: 887.10. BOC Sciences 12
Avermectin B1a aglycone It is an acid degradation product produced by hydrolysis of the disaccharide unit of avermectin. It is an inhibitor of nematode larval development. It has no paralytic activity. It is an anthelmintic in animal health. Synonyms: (6R,13S,25R)-22,23-didehydro-5-O-demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-[(1S)-1-methylpropyl]-milbemycin B. Grade: >95% by HPLC. CAS No. 71828-14-3. Molecular formula: C34H48O8. Mole weight: 584.74. BOC Sciences 12
Avermectin B1a monosaccharide It is an acid degradation product produced by selective hydrolysis of the terminal saccharide unit of avermectin. It is a potent inhibitor of nematode larval development. It has no paralytic activity. Synonyms: 4'-O-de(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-5-O-demethyl-avermectin A1a; 5-O-Demethyl-4'-O-de(2,6-dideoxy-3-O-methyl-α-L-glucopyranosyl)avermectin A1a; MSB 1a. Grade: >95% by HPLC. CAS No. 71831-09-9. Molecular formula: C41H60O11. Mole weight: 728.91. BOC Sciences 12
Averufin Averufin is produced by the strain of Asergillus sp. Ames tests showed a weak mutagenic effect. Synonyms: Averufine; 3,4,5,6-Tetrahydro-7,9,11-trihydroxy-2-methyl-2,6-epoxy-2H-anthra[2,3-b]oxocin-8,13-dione. CAS No. 14016-29-6. Molecular formula: C20H16O7. Mole weight: 368.34. BOC Sciences 12
Avidinorubicin Avidinorubicin is produced by the strain of Streptomyces avidinii. It has anti-gram positive and negative bacterial activity, and has cytotoxicity to tumor cells. Molecular formula: C60H86N4O22. Mole weight: 1215.34. BOC Sciences 12
Avrainvillamide Avrainvillamide is a fungal metabolite and monomeric form of stephacidin B that has been found in A. ochraceus. It is active against S. aureus, S. pyogenes, and E. faecalis (MICs = 12.5, 12.5, and 25 μg/ml, respectively). Avrainvillamide inhibits the growth of LNCaP, BT-549, T47D, and MALME-3M cancer cells with GI50 values of 0.24, 0.62, 0.21, and 0.41 μM, respectively. Synonyms: CJ-17,665; CJ17,665; CJ 17,665; 3,11,12,13,13aS,14-hexahydro-3,3,14,14-tetramethyl-8H,10H-7aS,12aS-(iminomethano)indolizino[6,7-h]pyrano[3,2-a]carbazole-8,16-dione 15-oxide. Grade: >95% by HPLC. CAS No. 269741-97-1. Molecular formula: C26H27N3O4. Mole weight: 445.52. BOC Sciences 12

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