BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Alldimycin A | It is produced by the strain of SE-2385-Al. Alldimycin A inhibited the growth of L1210 cells and the synthesis of DNA and RNA with IC50 of 0.005 ?/mL, 0.92 and 0.47 ?/mL, respectively. Synonyms: DTXSID40924150; Alldimycin A; Antibiotic ALR 3; 3-Ethyl-3,4,5,7,10-pentahydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 2,3,6-trideoxy-3-(dimethylamino)hexopyranoside; 5,12-Naphthacenedione,8-ethyl-7,8,9,10-tetrahydro-1,4,6,7,8-pentahydroxy-10-[[2,3,6-trideoxy-3-(dimethylamino)-a-L-lyxo-hexopyranosyl]oxy]-,[7R-(7a,8b,10b)]-. Grade: 95%. CAS No. 122397-46-0. Molecular formula: C28H33NO10. Mole weight: 543.56. |  |
| Alldimycin B | It is produced by the strain of SE-2385-Al. Synonyms: 2-ethyl-2,7,10,12-tetrahydroxy-6,11-dioxo-4-{[2,3,6-trideoxy-3-(dimethylamino)hexopyranosyl]oxy}-1,2,3,4,6,11-hexahydrotetracen-1-yl 2,3,6-trideoxy-3-(dimethylamino)hexopyranoside; DTXSID80913801; 5,12-Naphthacenedione, 8-ethyl-7,8,9,10-tetrahydro-1,4,6,8-tetrahydroxy-7,10-bis((2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-, (7R-(7alpha,8beta,10beta))-; 5,12-Naphthacenedione,8-ethyl-7,8,9,10-tetrahydro-1,4,6,8-tetrahydroxy-7,10-bis[[2,3,6-trideoxy-3-(dimethylamino)-a-L-lyxo-hexopyranosyl]oxy]-,[7R-(7a,8b,10b)]-; Alldimycin B; Alpharubicin II. Grade: 95%. CAS No. 97605-82-8. Molecular formula: C36H48N2O12. Mole weight: 700.77. | |
| Alldimycin C | It is produced by the strain of SE-2385-Al. Synonyms: CTK3I7025; DTXSID50915296; (7R,8R,10S)-7-[(2S,4S,5S,6S)-4-dimethylamino-5-hydroxy-6-methyl-oxan-2-yl]oxy-8-ethyl-1,4,6,8,10-pentahydroxy-9,10-dihydro-7H-tetracene-5,12-dione; 2-Ethyl-2,4,7,10,12-pentahydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 2,3,6-trideoxy-3-(dimethylamino)hexopyranoside; 5,12-Naphthacenedione, 8-ethyl-7,8,9,10-tetrahydro-1,4,6,8,10-pentahydroxy-7-((2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-, (7R-(7alpha,8beta,10beta))-. Grade: 95%. CAS No. 94818-02-7. Molecular formula: C28H33NO10. Mole weight: 543.56. | |
| Alliacol A | It is produced by the strain of Marasmium alliaceus. It has weak antibacterial and fungal activity and strong inhibition of DNA synthesis of Ehrlician ascites cancer cells (2-5 ?/mL). The reaction with cysteine to form an admixture greatly reduced the biological activity. Synonyms: DTXSID80229590; 8H-Oxireno[1,7a]indeno[3a,4-b]furan-6(2H)-one,hexahydro-4a-hydroxy-2,9,9-trimethyl-5-methylene-, (1aR,2R,4aS,7aS,9aR)-; Alliacolide II. Grade: 95%. CAS No. 79232-29-4. Molecular formula: C15H20O4. Mole weight: 264.32. | |
| Alliacol B | It is produced by the strain of Marasmium alliaceus. It has weak antibacterial and fungal activity and strong inhibition of DNA synthesis of Ehrlician ascites cancer cells (2-5 ?/mL). The reaction with cysteine to form an admixture greatly reduced the biological activity. Synonyms: NSC 350186; 8H-Oxireno(1,7a)indeno(3a,4-b)furan-6(2H)-one, 3,4,9,9a-tetrahydro-5-(hydroxymethyl)-2,9,9-trimethyl-, (2R-(1aR*,2alpha,7aS*,9aalpha))-; (1aR,2R,7aS,9aR)-3,4,9,9a-Tetrahydro-5-hydroxymethyl-2,9,9-trimethyl-8H-oxireno[1,7a]indeno[3a,4-b]furan-6(2H)-one; 12-Hydroxydehydroalliacolide. Grade: 98%. CAS No. 79232-33-0. Molecular formula: C15H20O4. Mole weight: 264.32. | |
| Alliacolide | It is produced by the strain of Marasmius alliaceus (Basidiomycetes). It inhibits the activity of Ehrlician ascites cancer cells. Synonyms: Alliacolide-1; 8H-Oxireno[1,4-b]furan-6(2H)-one, hexahydro-4a-hydroxy-2,5,9,9-tetramethyl-, [2R-(1aR*,2alpha,4abeta,5alpha,7aS*,9aalpha)]-; (1aR,2R,4aS,5S,7aS,9aR)-4a-hydroxy-2,5,9,9-tetramethylhexahydro-8H-oxireno[2',3':1,7a]indeno[3a,4-b]furan-6(2H)-one. CAS No. 66389-08-0. Molecular formula: C15H22O4. Mole weight: 266.33. | |
| (-)-allo-Protolichesterinic acid | (-)-allo-Protolichesterinic acid can inhibit 5-lipoxygenase in vitro. CAS No. 22800-27-7. Molecular formula: C19H32O4. Mole weight: 324.45. | |
| Allorhizin | It is the constituent of Psoroma allorhizum. Synonyms: 11H-Dibenzo[b,e][1,4]dioxepin-6-carboxaldehyde, 2,7-dichloro-3-hydroxy-8-methoxy-1,4,9-trimethyl-11-oxo-. CAS No. 84592-16-5. Molecular formula: C18H14Cl2O6. Mole weight: 397.21. | |
| Alnumycin | It is produced by the strain of Streptomyces sp. DSM 11575. The antibacterial spectrum is narrow, and it only has the activity of resistant bacillus subtilis, gambogic micrococcus and other gram-positive bacteria, but has no effect on gram-negative bacteria. It can inhibit the growth of K562 human leukemic cells with IC50 of 0.53 ?/mL. Molecular formula: C22H24O8. Mole weight: 416.42. | |
| α-{[2-(9-Fluorenylmethoxycarbonyl)amino]ethyldithio}isobutyric acid | α-{[2-(9-Fluorenylmethoxycarbonyl)amino]ethyldithio}isobutyric acid. Synonyms: alpha-{[2-(9-Fluorenylmethoxycarbonyl)amino]ethyldithio}isobutyric acid; Fmoc-AEDI-OH; 2-{2-[(9-Fluorenylmethoxycarbonyl)amino]ethyldithio}-2-methylpropanoic acid. CAS No. 1823244-38-7. Molecular formula: C21H23NO4S2. Mole weight: 417.55. | |
| α-{[2-(t-Butoxycarbonyl)amino]ethyldithio}isobutyric acid | α-{[2-(t-Butoxycarbonyl)amino]ethyldithio}isobutyric acid. Synonyms: Boc-AEDI-OH; 2-{2-[(t-Butoxycarbonyl)amino]ethyldithio}-2-methylpropanoic acid; 2-[[2-(tert-Butoxycarbonylamino)ethyl]dithio]isobutyric acid; alpha-{[2-(t-Butoxycarbonyl)amino]ethyldithio}isobutyric acid. CAS No. 144700-78-7. Molecular formula: C11H21NO4S2. Mole weight: 295.40. | |
| α-Casein (90-95) | α-Casein (90-95). Synonyms: alpha-Casein (90-95); a-Casein (90-95); H-Arg-Tyr-Leu-Gly-Tyr-Leu-OH. CAS No. 83471-50-5. Molecular formula: C38H57N9O9. Mole weight: 783.91. | |
| alpha-Collatolic acid | alpha-Collatolic acid. Synonyms: Collatolic acid-A''; NSC 646010; 11H-Dibenzo(b,e)(1,4)dioxepin-7-carboxylic acid, 8-hydroxy-3-methoxy-11-oxo-1,6-bis(2-oxoheptyl)-; 3-hydroxy-9-methoxy-6-oxo-1,7-bis(2-oxoheptyl)benzo[b][1,4]benzodioxepine-2-carboxylic acid; α-Collatolic acid. CAS No. 522-52-1. Molecular formula: C29H34O9. Mole weight: 526.57. | |
| α-Conotoxin EI (free acid) | α-Conotoxin EI (free acid) is a nicotinic acetylcholine receptor ligand. Synonyms: α-Conotoxin El, Conus ermineus, free acid; H-Arg-Asp-Hyp-Cys-Cys-Tyr-His-Pro-Thr-Cys-Asn-Met-Ser-Asn-Pro-Gln-Ile-Cys-OH (Disulfide bridge: Cys4-Cys10, Cys5-Cys18). Grade: ≥95%. CAS No. 1926163-14-5. Molecular formula: C83H124N26O28S5. Mole weight: 2094.37. | |
| α-Conotoxin MI | α-Conotoxin MI has been isolated from the venom of the sea snail Conus imperialis. The conotoxin is a ligand for nicotinic acetylcholine receptors. Synonyms: Alpha-Conotoxin MI; Conotoxin G I, 1-(N2-glycyl-L-arginine)-4-L-histidine-9-L-lysine-10-L-asparagine-. CAS No. 88217-10-1. Molecular formula: C58H88N22O17S4. Mole weight: 1493.72. | |
| α-Factor Mating Pheromone, yeast acetate | α-Factor Mating Pheromone, yeast acetate is a tridecapeptide secreted by Saccharomyces cerevisiae α cells via the Ste2p receptor, which facilitates in regulating the mating in yeast. Synonyms: H-Trp-His-Trp-Leu-Gln-Leu-Lys-Pro-Gly-Gln-Pro-Met-Tyr-OH.CH3CO2H; Mating Factor α acetate; alphaSC1-Pheromone acetate; L-tryptophyl-L-histidyl-L-tryptophyl-L-leucyl-L-glutaminyl-L-leucyl-L-lysyl-L-prolyl-glycyl-L-glutaminyl-L-prolyl-L-methionyl-L-tyrosine acetic acid. Grade: ≥95%. Molecular formula: C84H118N20O19S. Mole weight: 1744.05. | |
| α-Gliadin (31-43) | α-Gliadin (31-43) is the 31-43 amino acid residue of α-Gliadin responsible for the innate immune response in celiac disease patients. Synonyms: alpha-Gliadin (31-43); H-Leu-Gly-Gln-Gln-Gln-Pro-Phe-Pro-Pro-Gln-Gln-Pro-Tyr-OH. Molecular formula: C71H102N18O20. Mole weight: 1527.8. | |
| α-Me-Asp-OH | α-Me-Asp-OH. Synonyms: H-aMeAsp-OH; 2-Methyl-L-Aspartic Acid; alpha-methylaspartic acid; alpha-Me-Asp-OH; α Me Asp OH; alpha Me Asp OH. Grade: 95%. CAS No. 3227-17-6. Molecular formula: C5H9NO4. Mole weight: 147.13. | |
| α-Me-D-Leu-OH | α-Me-D-Leu-OH. Synonyms: H-D-aMeLeu-OH; (R)-2-Amino-2,4-dimethylpentanoic acid; alpha-Me-D-Leu-OH; α Me D Leu OH; alpha Me D Leu OH. CAS No. 29589-03-5. Molecular formula: C7H15NO2. Mole weight: 145.2. | |
| α-Me-D-Tyr-OH | α-Me-D-Tyr-OH. Synonyms: H-D-aMeTyr-OH; Demser; (R)-2-Amino-3-(4-hydroxyphenyl)-2-methylpropanoic acid; (R)-metirosine; alpha-Me-D-Tyr-OH; α Me D Tyr OH; alpha Me D Tyr OH. Grade: 95%. CAS No. 672-86-6. Molecular formula: C10H13NO3. Mole weight: 195.21. | |
| α-Me-D-Val-OH HCl | α-Me-D-Val-OH HCl. Synonyms: alpha Me D Val OH HCl. Molecular formula: C6H14ClNO2. Mole weight: 167.63. | |
| α-Me-Gly(Propargyl)-OH | α-Me-Gly(Propargyl)-OH. Synonyms: H-aMePra-OH; (S)-2-Amino-2-methylpent-4-ynoic acid; alpha-methyl-D-Propargylglycine; alpha-Me-Gly(Propargyl)-OH. Grade: 95%. CAS No. 1231709-27-5. Molecular formula: C6H9NO2. Mole weight: 127.14. | |
| α-Methyl-4-fluoro-D-phenylalanine | α-Methyl-4-fluoro-D-phenylalanine. Synonyms: H-D-(Me)Phe(4-F)-OH. Grade: ≥ 98% (HPLC). CAS No. 422568-68-1. Molecular formula: C10H12FNO2. Mole weight: 197.21. | |
| α-Methyl-4-fluoro-L-phenylalanine | α-Methyl-4-fluoro-L-phenylalanine is used in the discovery of series of zwitterionic CCR3 antagonists. Synonyms: H-(Me)Phe(4-F)-OH; α-Me-L-Phe(4-F)-OH; (S)-2-Amino-2-methyl-3-(4-fluorophenyl)propanoic acid; H-L-α-Me-Phe(4-F)-OH; alpha-methyl-L-4-Fluorophenylalanine; (2S)-2-amino-3-(4-fluorophenyl)-2-methylpropanoic acid. Grade: ≥ 98% (HPLC). CAS No. 130855-57-1. Molecular formula: C10H12FNO2. Mole weight: 197.21. | |
| α-methyl-D-2-Fluorophe | α-methyl-D-2-Fluorophe. Synonyms: alpha-methyl-D-2-Fluorophe; alpha-Methyl-D-2-fluorophenylalanine. CAS No. 1336086-97-5. Molecular formula: C10H12FNO2. Mole weight: 197.21. | |
| α-Methyl-DL-phenylalanine | α-Methyl-DL-phenylalanine. Synonyms: α-Me-DL-Phe-OH; (+/-)-2-Amino-2-methyl-3-phenylpropionic acid. Grade: ≥ 98% (HPLC). CAS No. 1132-26-9. Molecular formula: C10H13NO2. Mole weight: 179.2. | |
| α-Methyl-DL-phenylalanine methyl ester hydrochloride | α-Methyl-DL-phenylalanine methyl ester hydrochloride. Synonyms: H-DL-(Me)Phe-OMe HCl; α-Me-DL-Phe-OMe HCl; methyl 2-amino-2-methyl-3-phenylpropanoate hydrochloride; alpha-Methyl-DL-phenylalanine methyl ester hydrochloride; H-alpha-Me-DL-Phe-OMe HCl; 2-Amino-2-methyl-3-phenyl-propionsaeure-methylester Hydrochloride. Grade: ≥ 98%. CAS No. 64665-60-7. Molecular formula: C11H15NO2·HCl. Mole weight: 229.70. | |
| α-Methyl-DL-tryptophan methyl ester | A tryptophan derivative as tachykinin antagonist. Uses: A tryptophan derivative as tachykinin antagonist. Synonyms: H-DL-(Me)Trp-OMe; DL-α-METHYLTRYPTOPHAN METHYL ESTER HYDROCHLORIDE; methyl 2-amino-3-(1H-indol-3-yl)-2-methylpropanoate; H-alpha-Me-DL-Trp-OMe; ALPHA-METHYL-DL-TRYPTOPHAN METHYL ESTER; H-2-Me-DL-Try-OMe; Tryptophan, alpha-methyl-, methyl ester; alpha-Methyl-D,L-tryptophan Methyl Ester. Grade: ≥ 99% (TLC). CAS No. 114524-80-0. Molecular formula: C13H16N2O2. Mole weight: 232.28. | |
| α-Methyl-DL-valine | α-Methyl-DL-valine. Synonyms: α-Me-DL-Val-OH; 2-Amino-2,3-dimethylbutanoic acid; H-Alpha-Me-Dl-Val-Oh; alpha-Methyl-DL-valine; 2-amino-2,3-dimethylbutyric acid; (R)-Methylvaline; Valine,2-methyl-; H Alpha Me DL Val OH. Grade: ≥ 99% (assay). CAS No. 26287-62-7. Molecular formula: C6H13NO2. Mole weight: 131.17. | |
| α-Methyl-D-phenylalanine | α-Methyl-D-phenylalanine. Synonyms: α-Me-D-Phe-OH; (R)-2-Amino-2-methyl-3-phenylpropanoic acid. Grade: ≥ 99% (Chiral HPLC). CAS No. 17350-84-4. Molecular formula: C10H13NO2. Mole weight: 179.2. | |
| α-methyl-D-Serine(OtBu) | α-methyl-D-Serine(OtBu). Molecular formula: C8H17NO3. Mole weight: 175.23. | |
| α-Methyl-D-valine | α-Methyl-D-valine. Uses: Used in the preparation of medicinal and herbicidal agents. Synonyms: α-Me-D-Val-OH. Grade: ≥ 98% (NMR). CAS No. 53940-82-2. Molecular formula: C6H13NO2. Mole weight: 131.17. | |
| α-methyl-L-2-Fluorophe | α-methyl-L-2-Fluorophe. Synonyms: alpha-methyl-L-2-Fluorophe; alpha-Methyl-L-2-fluorophenylalanine. CAS No. 130780-36-8. Molecular formula: C10H12FNO2. Mole weight: 197.21. | |
| α-Methyl-L-leucine | α-Methyl-L-leucine. Synonyms: H-(Me)Leu-OH; α-Me-L-Leu-OH; H-α-Me-L-Leucine; (S)-alpha-Methylleucine; (2S)-2-amino-2,4-dimethylpentanoic acid; 2-Methylleucine; H-ALPHA-ME-LEU-OH; alpha-Methylleucine. Grade: 99-100% (HPLC). CAS No. 105743-53-1. Molecular formula: C7H15NO2. Mole weight: 145.20. | |
| α-Methyl-L-phenylalanine | α-Methyl-L-phenylalanine. Synonyms: α-Me-L-Phe-OH; (S)-2-Amino-2-methyl-3-phenylpropionic acid. Grade: ≥ 99% (HPLC). CAS No. 23239-35-2. Molecular formula: C10H13NO2. Mole weight: 179.20. | |
| α-Methyl-L-serine | α-Methyl-L-serine. Uses: A potential chiral building blocks for the synthesis of different α -methyl α -amino acids. Synonyms: 2-Methyl-L-serine; (S)-2-Amino-3-hydroxy-2-methylpropanoic acid. Grade: 98%. CAS No. 16820-18-1. Molecular formula: C4H9NO3. Mole weight: 119.12. | |
| α-methyl-L-Serine(OtBu) | α-methyl-L-Serine(OtBu). CAS No. 114396-73-5. Molecular formula: C8H17NO3. Mole weight: 175.23. | |
| α-Methyl-L-valine | Used in the preparation of medicinal and herbicidal agents. Uses: Used in the preparation of medicinal and herbicidal agents. Synonyms: H-(Me)Val-OH; (S)-2-Amino-2,3-dimethylbutanoic acid; α-Me-L-Val-OH; (S)-(-)-α-Methylvaline; (2S)-2-Amino-2,3-dimethylbutanoic acid; L-α-methylvaline; ALPHA-METHYL-L-VALINE; 3-Methyl-L-isovaline; alpha-methylvaline. Grade: ≥ 99.9% (Chiral purity). CAS No. 53940-83-3. Molecular formula: C6H13NO2. Mole weight: 131.18. | |
| α-MSH (11-13) | α-MSH (11-13) is a fragment of Alpha-melanocyte-stimulating hormone (α-MSH), which is a neuropeptide with immunomodulatory properties. Synonyms: H-LYS-PRO-VAL-OH ACETATE SALT; H-LYS-PRO-VAL-OH ACOH; ALPHA-MSH (11-13); ALPHA-MSH (11-13) ACETATE SALT; msh(11-13.alpha.-MSH (11-13) (free acid); H-Lys-Pro-Val-OH; alpha-Msh (11-13) (free acid) acetate salt. CAS No. 67727-97-3. Molecular formula: C16H30N4O4. Mole weight: 342.43. | |
| α-Naphthocyclinone | α-Naphthocyclinone. Synonyms: 6,13-Methanonaphtho[2',3':5,6]cyclohepta[1,2-g]-2-benzopyran-9-butanoic acid, 6-(acetyloxy)-1,3,4,6,8,11,13,14-octahydro-β,7,10,12,15-pentahydroxy-3-(2-methoxy-2-oxoethyl)-1-methyl-8,11,14-trioxo-, (βR,1S,3R,6S,13R)-; alpha-Naphthocyclinone; (R)-4-((1S,3R,6S,13R)-6-acetoxy-7,8,12,15-tetrahydroxy-3-(2-methoxy-2-oxoethyl)-1-methyl-10,11,14-trioxo-1,3,4,6,10,11,13,14-octahydro-6,13-methanonaphtho[2',3':5,6]cyclohepta[1,2-g]isochromen-9-yl)-3-hydroxybutanoic acid; a-Naphthocyclinone. CAS No. 54826-93-6. Molecular formula: C33H30O15. Mole weight: 666.58. | |
| α-Neoendorphin 1-8 | α-Neoendorphin (1-8) is a 8-amino acid peptide derived from the N-terminal of α-Neoendorphin which is an endogenous opioid peptide. Synonyms: alpha-Neoendorphin (1-8); H-Tyr-Gly-Gly-Phe-Leu-Arg-Lys-Tyr-OH; a-Neoendorphin (1-8). CAS No. 83339-89-3. Molecular formula: C49H70N12O11. Mole weight: 1003.15. | |
| α-Prumycin HCl | α-Prumycin HCl is a carbohydrate antibiotic produced by Str. sp. F-1028. It has anti-fungal activity and weak anti-individual bacterial activity. CAS No. 54612-75-8. Molecular formula: C8H19Cl2N3O4. Mole weight: 292.16. | |
| α-Synuclein (32-37) (human) | α-Synuclein (32-37) (human). Synonyms: α-Synuclein (43-48) (human); H-Lys-Thr-Lys-Glu-Gly-Val-OH; L-Valine, L-lysyl-L-threonyl-L-lysyl-L-α-glutamylglycyl-; L-lysyl-L-threonyl-L-lysyl-L-alpha-glutamyl-glycyl-L-valine; H-KTKEGV-OH. Grade: ≥95%. CAS No. 865377-33-9. Molecular formula: C28H52N8O10. Mole weight: 660.76. | |
| α-Synuclein (34-45) (human) | The Parkinson's disease-associated protein α-synuclein (α-syn) is not only expressed in the cytoplasm of neurons, but also secreted in the extracellular space and internalized into glial cells through a lipid raft dependent process. The tilted peptide α-synuclein(67-78) has a high affinity with cholesterol and is toxic to cultured astrocytes. The glycosphingolipid-binding domain of alpha-synuclein (34-45) encapsulates a cholesterol-recognition consensus motif with a low affinity and no toxicity. Synonyms: α-syn (34-45) (human); H-Lys-Glu-Gly-Val-Leu-Tyr-Val-Gly-Ser-Lys-Thr-Lys-OH; L-Lysine, L-lysyl-L-α-glutamylglycyl-L-valyl-L-leucyl-L-tyrosyl-L-valylglycyl-L-seryl-L-lysyl-L-threonyl-. Grade: ≥95%. CAS No. 2170181-52-7. Molecular formula: C59H101N15O18. Mole weight: 1308.52. | |
| α-Synuclein (45-54) (human) | A pathogenic feature of Parkinson's disease (PD) is the aggregation of α-synuclein (α-syn) into toxic fibrils, and most of the early mutations are located between residues 46 and 53. Synonyms: H-Lys-Glu-Gly-Val-Val-His-Gly-Val-Ala-Thr-OH; L-Threonine, L-lysyl-L-α-glutamylglycyl-L-valyl-L-valyl-L-histidylglycyl-L-valyl-L-alanyl-; α-syn (45-54) (human). Grade: ≥95%. CAS No. 2243206-98-4. Molecular formula: C43H73N13O14. Mole weight: 996.12. | |
| α-Synuclein (61-95) (human) | α-synuclein (61-95) has originally been isolated from the insoluble core of Alzheimer's disease (AD) amyloid plaque. Synonyms: H-Glu-Gln-Val-Thr-Asn-Val-Gly-Gly-Ala-Val-Val-Thr-Gly-Val-Thr-Ala-Val-Ala-Gln-Lys-Thr-Val-Glu-Gly-Ala-Gly-Ser-Ile-Ala-Ala-Ala-Thr-Gly-Phe-Val-OH; NAC; Non-Aβ Component of Alzheimer's Disease Amyloid. CAS No. 154040-19-4. Molecular formula: C141H235N39O49. Mole weight: 3260.61. | |
| α-Synuclein (67-78) (human) | The Parkinson's disease-associated protein α-synuclein (α-syn) is not only expressed in the cytoplasm of neurons, but also secreted in the extracellular space and internalized into glial cells through a lipid raft dependent process. The tilted peptide α-synuclein(67-78) has a high affinity with cholesterol and is toxic to cultured astrocytes. The glycosphingolipid-binding domain of alpha-synuclein (34-45) encapsulates a cholesterol-recognition consensus motif with a low affinity and no toxicity. Synonyms: α-syn (67-78) (human); H-Gly-Gly-Ala-Val-Val-Thr-Gly-Val-Thr-Ala-Val-Ala-OH; L-Alanine, glycylglycyl-L-alanyl-L-valyl-L-valyl-L-threonylglycyl-L-valyl-L-threonyl-L-alanyl-L-valyl-. Grade: ≥95%. CAS No. 2243206-99-5. Molecular formula: C43H76N12O15. Mole weight: 1001.14. | |
| α-Synuclein (71-82) (human) | A characteristic feature of individuals with neurodegenerative diseases is the deposition of α-synuclein (α-syn) fibrils in the Lewy body. The central hydrophobic region of α-synuclein is similar to the α-synuclein peptide (71-82), which is considered to be the cause of protein aggregation. Furthermore, α-synuclein (71-82) forms amyloid fibrillary with similar morphology to α-synuclein, suggesting that this region participates in the fibrillogenic core of the full-length protein. Synonyms: α-syn (71-82) (human); H-Val-Thr-Gly-Val-Thr-Ala-Val-Ala-Gln-Lys-Thr-Val-OH. Grade: ≥95%. CAS No. 332867-16-0. Molecular formula: C51H92N14O17. Mole weight: 1173.36. | |
| α-Synuclein Binding Peptide | α-Synuclein Binding Peptide is a 10-residue peptide antagonist, corresponding to the sequence of the α-synuclein binding peptide, and effectively inhibits α-synuclein aggregation and related toxicity at 1:1 stoichiometry. Synonyms: L-Alaninamide, N2-acetyl-L-lysyl-L-α-aspartylglycyl-L-isoleucyl-L-valyl-L-asparaginylglycyl-L-valyl-L-lysyl-; Ac-Lys-Asp-Gly-Ile-Val-Asn-Gly-Val-Lys-Ala-NH2; α-syn Binding Peptide. Grade: ≥95%. CAS No. 2243207-00-1. Molecular formula: C45H80N14O14. Mole weight: 1041.20. | |
| Alphitonin | Alphitonin is a metabolite related to flavonoids, which is isolated from the heartwood of Australian red ash. Alphitonin has anti-diabetic and anti-oxidant effects. Grade: >95% by HPLC. CAS No. 493-36-7. Molecular formula: C15H12O7. Mole weight: 304.25. | |
| Alphostatin | BMG59-R2 is a peptide antibiotic produced by Bacillus megaterium BNG59-R2. It can inhibit the activity of alkaline phosphatase and also has anti-tumor activity. Synonyms: L-Glutamic acid, N-(N(sup 2)-(N-(N-L-isoleucyl-L-isoleucyl)-O-phosphono-L-seryl)-L-glutaminyl)-, hydrate; BMG59-R2. Grade: >98%. CAS No. 90119-88-3. Molecular formula: C25H45N6O13P. Mole weight: 668.63. | |
| Altechromone A | Altechromone A is produced from Alternaria brassicicola ML-P08. Altechromone A shows antimicrobial activity against Bacillus subtilis, Escherichia coli, Pseudomonas fluorescens and Candida albicans with the MICs of 3.9, 3.9, 1.8, and 3.9 ug/ml, respectively. Synonyms: 7-Hydroxy-2,5-dimethylchromone; 7-Hydroxy-2,5-dimethyl-4H-1-benzopyran-4-one. Grade: 98.0%. CAS No. 38412-47-4. Molecular formula: C11H10O3. Mole weight: 190.19. | |
| Alteichin | It is produced by the strain of Alternaria eichorniae. Phytotoxic substances. Synonyms: alterperylenol; Alteichin; GRK18WHV7F; C10295; (+)-Alterperylenol; AC1L2PAW; Alterperylnol; CHEBI:2614; DTXSID10237401; ZINC4098645; AKOS030213167; (1S,12aR,12bS)-1,4,9,12a-tetrahydroxy-2,12b-dihydro-1H-perylene-3,10-dione; Q27105736; 3,10-Perylenedione,1,2,12a,12b-tetrahydro-1,4,9,12a-tetrahydroxy-, (1S,12aR,12bS)-; 3,10-Perylenedione, 1,2,12a,12b-tetrahydro-1,4,9,12a-tetrahydroxy-, (1alpha,12abeta,12balpha)-(+)-. Grade: 95%. CAS No. 88899-62-1. Molecular formula: C20H14O6. Mole weight: 350.32. | |
| Altemicidin | It is produced by the strain of Streptomyces sioyaensis. It has acaricidal and anti-tumor activity. The inhibition IC50 of L1210 and IMC cancer cells was 0.84 and 0.82 ?/mL. Synonyms: CTK4B4358; DTXSID20925120; 1H-Cyclopenta[c]pyridine-7-carboxylicacid,4-(aminocarbonyl)-7-[[2-(aminosulfonyl)acetyl]amino]-2,4a,5,6,7,7a-hexahydro-6-hydroxy-2-methyl-,(4aR,6S,7R,7aS)-; LS-136376; Q15410226; 6-Hydroxy-7-({[(1-hydroxy-2-sulfamoylethylidene)amino]oxy}carbonyl)-2-methyl-2,4a,5,6,7,7a-hexahydro-1H-cyclopenta[c]pyridine-4-carboximidic acid. Grade: 99%. CAS No. 125399-82-8. Molecular formula: C13H20N4O7S. Mole weight: 376.38. | |
| Alterlactone | Alterlactone is produced from the endolichenic fungus Ulocladium sp. Alterlactone shows strong radical scavenging activity. Synonyms: 4,9,10-trihydroxy-2-methoxydibenzo[c,e]oxepin-5(7H)-one. Grade: 97.5%. CAS No. 1030376-89-6. Molecular formula: C15H12O6. Mole weight: 288.25. | |
| Alternapyrone | Alternapyrone is a polyketide produced in A. oryzae heterologously expressing the A. solani-derived polyketide synthase gene alt5. CAS No. 676340-02-6. Molecular formula: C28H44O3. Mole weight: 428.65. | |
| Alternaric acid | It is produced by the strain of Alternaria solani. The main antifungal activity was 0.1-1.0 ?/mL, which inhibited the spore germination of Plomonas aeruginosa, Porphyra porphyra and Black grapevine panicle. Synonyms: D-Arabinonic acid,4,5-dideoxy-2-C-((1E)-7-((6R)-5,6-dihydro-4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)-4-methylene-7-oxo-1-heptenyl)-4-ethyl; 3-Nonenoic acid,9-(5,6-dihydro-4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)-2-hydroxy-2-(1-hydroxy-2-methylbutyl)-6-methylene-9-oxo-,(6R-(3(2S*(1R*,2S*),3E),6R*)); 3-Octenoic acid,2-hydroxy-2-(1-hydroxy-2-methylbutyl)-6-methylene-8-[(tetrahydro-6-methyl-2,4-dioxopyran-3-yl)carbonyl]-(8CI); Alternaric acid (6CI,7CI); D-Arabinonic acid,4,5-dideoxy-2-C-[(1E)-7-[(6R)-5,6-dihydro-4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl]-4-methylene-7-oxo-1-heptenyl]-4-ethyl-(9CI). Grade: 98%. CAS No. 10088-62-7. Molecular formula: C21H30O8. Mole weight: 410.46. | |
| Alternariol 9-methyl ether | Alternariol monomethyl ether is produced from the media of Alternaria alternata strain 261. Alternariol monomethyl ether, an Alternaria toxin, is a strong mutagen in Escherichia coli strain ND-160. Alternariol monomethyl ether possesses cytotoxic and immunosuppressive properties. It has genotoxic properties and can cause oxidative DNA damage. Synonyms: 2-Biphenylcarboxylic acid, 2',3,4'-trihydroxy-5-methoxy-6'-methyl-, δ-lactone; 6H-Dibenzo[b,d]pyran-6-one, 3,7-dihydroxy-9-methoxy-1-methyl-; 3,7-Dihydroxy-9-methoxy-1-methyl-6H-dibenzo[b,d]pyran-6-one; Alternariol 4-O-methyl ether; Alternariol 9-O-methyl ether; Alternariol monomethyl ether; Alternariol-5-O-methyl ether; AME; Djalonensone; NSC 638262. Grade: 98%. CAS No. 23452-05-3. Molecular formula: C15H12O5. Mole weight: 272.25. | |
| Alternariol monomethyl ether | The 50 ppm acetonitrile solution of Alternariol monomethyl ether, shows activities as a cholinesterase inhibitor as well as an anti-fungal agent, could be commonly used as a standard solution. It is an alternaria mycotoxin and genotoxin, which can inhibit the activity of DNA-topoisomerases. Synonyms: 6H-Dibenzo[b,d]pyran-6-one, 3,7(3,9 or 7,9)-dihydroxy-9(7 or 3)-methoxy-1-methyl-; 3,7(3,9 or 7,9)-Dihydroxy-9(7 or 3)-methoxy-1-methyl-6H-dibenzo[b,d]pyran-6-one; Alternariol, methyl ether. Grade: >95%. CAS No. 26894-49-5. Molecular formula: C15H12O5. Mole weight: 272.25. | |
| Altertoxin I | Altertoxin I, a sort of natural mycotoxin, could be obtained from Alternaria fungi and has been found to restrain human topoisomerase II as well as bacterial gyrase. Altertoxin I (and other altertoxins) inhibit the HIV replication. Synonyms: Altertoxin-I; BC9625200. Grade: ≥97%. CAS No. 56258-32-3. Molecular formula: C20H16O6. Mole weight: 352.34. | |
| Althiomycin | It is produced by the strain of Streptomyces althiotious. Anti-Gram-positive bacteria (weak) and E. coli (weak). Synonyms: Althiomycin; Altiomycin; NSC 102809; 4-Thiazolecarboxamide, N-(1-(4-((2,5-dihydro-4-methoxy-2-oxo-1H-pyrrol-1-yl)carbonyl)-4,5-dihydro-2-thiazolyl)-2-hydroxyethyl)-2-((hydroxyimino)methyl)-; NSC102809. CAS No. 12656-40-5. Molecular formula: C16H17N5O6S2. Mole weight: 439.47. | |
| Altiloxin A | It is produced by the strain of Phoma asparagi Sacc ALD-8. It is a plant toxin that can inhibit the growth of roots. Synonyms: (1as,3s,4r,4ar,8ar)-3-hydroxy-3,4a,8,8-tetramethyloctahydro-1ah-naphtho[1,8a-b]oxirene-4-carboxylic acid; (-)-Altiloxin A; CTK5H1580; DTXSID20896902; 3H-Naphth(1,8a-b)oxirene-4-carboxylic acid, octahydro-3-hydroxy-3,4a,8,8-tetramethyl-, (1aS,3R,4R,4aR,8aR)-; 3H-Naphth(1,8a-b)oxirene-4-carboxylic acid, octahydro-3-hydroxy-3,4a,8,8-tetramethyl-, (1aS-(1aalpha,3beta,4alpha,4aalpha,8aS*))-. Grade: 95%. CAS No. 92675-11-1. Molecular formula: C15H24O4. Mole weight: 268.35. | |
| Altiloxin B | It is produced by the strain of Phoma asparagi Sacc ALD-8. Plant toxin. Synonyms: (1aS,8aS)-7α-Chlorooctahydro-3β-hydroxy-3,4aα,8,8-tetramethyl-3H-naphth[1,8a-b]oxirene-4α-carboxylic acid. CAS No. 92675-14-4. Molecular formula: C15H23O4Cl. Mole weight: 302.79. | |
| Altromycin A | It is produced by the strain of Actinomycetes AB 1246E-26. It has anti-Gram-positive bacteria activity, and the MIC for Streptococcus and Staphylococcus is between 0.2-3.12ug/mL. It also has an inhibitory effect on a variety of tumor cells. Synonyms: methyl 2-(3,5-dihydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)-2-(2-(2,3-dimethyloxiran-2-yl)-11-hydroxy-10-(5-((5-hydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-3-yl)oxy)-4,6-dimethyl-4-(methylamino)tetrahydro-2H-pyran-2-yl)-4,7,12-trioxo-7,12-dihydro-4H-naphtho[2,3-h]chromen-5-yl)-2-hydroxyacetate; D-glycero-D-manno-Octonicacid,3,7-anhydro-8-deoxy-2-C-[2-(2,3-dimethyloxiranyl)-7,12-dihydro-11-hydroxy-4,7,12-trioxo-10-[2,3,6-trideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-D-ribo-hexopyranosyl)-3-C-methyl-3-(methylamino)-a-L-lyxo-hexopyranosyl]-4H-anthra[1,2-b]pyran-5-yl]-5-O-methyl-,methyl ester, (2x)-(9CI); 4H-Anthra[1,2-b]pyran, D-glycero-D-manno-octonic acid deriv. Grade: 95%. CAS No. 128439-47-4. Molecular formula: C46H57NO18. Mole weight: 911.94. | |
| Altromycin B | It is produced by the strain of Actinomycetes AB 1246E-26. It has anti-Gram-positive bacteria activity, and the MIC for Streptococcus and Staphylococcus is between 0.2-3.12ug/mL. It also has an inhibitory effect on a variety of tumor cells. Synonyms: GTPL10964; Octonic acid, 3,7-anhydro-8-deoxy-2-C-(2-(2,3-dimethyloxiranyl)-7,12-dihydro-11-hydroxy-4,7,12-trioxo-10-(2,3,6-trideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-D-ribo-hexopyranosyl)-3-(dimethylamino)-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-4H-anthra(1,2-b)pyran-5-yl)-5-O-methyl-, methyl ester; 4H-Anthra[1,2-b]pyran,D-glycero-D-manno-octonic acid deriv.; D-glycero-D-manno-Octonicacid,3,7-anhydro-8-deoxy-2-C-[2-(2,3-dimethyloxiranyl)-7,12-dihydro-11-hydroxy-4,7,12-trioxo-10-[2,3,6-trideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-D-ribo-hexopyranosyl)-3-(dimethylamino)-3-C-methyl-a-L-lyxo-hexopyranosyl]-4H-anthra[1,2-b]pyran-5-yl]-5-O-methyl-,methyl ester, (2x)-. Grade: 95%. CAS No. 128461-00-7. Molecular formula: C47H59NO18. Mole weight: 925.96. | |
| AM 4299 A | AM 4299 A is a thiol protease inhibitor produced by Chromelosporium fulvum M4299. Synonyms: Oxiranecarboxylic acid, 3-(((1-(((5-hydroxypentyl)amino)carbonyl)-3-methylbutyl)amino)carbonyl)-. Grade: >98%. CAS No. 160825-48-9. Molecular formula: C15H26N2O6. Mole weight: 330.38. | |
| AM 4299 B | AM 4299 B is a thiol protease inhibitor produced by Chromelosporium fulvum M4299. Synonyms: N(sup 6)-(N-((3-Carboxyoxiranyl)carbonyl)-L-leucyl)-L-lysine hydrate. Grade: >98%. CAS No. 160825-49-0. Molecular formula: C16H27N3O7. Mole weight: 373.40. | |
| Amicenomycin A | It is produced by the strain of Streptomyces sp. MJ384-46F6. It has anti-gram-positive bacterial activity. Molecular formula: C43H56O16. Mole weight: 828.89. | |
| Amicenomycin B | It is produced by the strain of Streptomyces sp. MJ384-46F6. It has weak anti-gram-positive bacterial activity. Molecular formula: C43H56O16. Mole weight: 828.89. | |
| Amicetin | It is produced by the strain of Streptomuces vinaceusdrappus. It is mainly resistant to gram-positive bacteria and Mycobacterium. The MIC for S.aureus 209P and Mycobacterium tuberculosis H37 Rv were 2.0 and 0.5 μg/mL, respectively, and for Mycoplasma pneumoniae was 12.5 μg/mL. Molecular formula: C29H42N6O9. Mole weight: 618.68. | |
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