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Actofunicone
It is produced by the strain of Talararomyces flavus FKI-0076. Actofunicone is an antifungal activity enhancer of Miconazole. Synonyms: FKI-0076; Benzoic acid, 2-((6-(2-(acetyloxy)propyl)-4-oxo-4H-pyran-3-yl)carbonyl)-3,5-dimethoxy-, methyl ester, (+)-. CAS No. 358376-44-0. Molecular formula: C21H22O9. Mole weight: 418.39.
Adechlorin
Adechlorin is a nucleoside compound produced from Actinomadura sp. OMR-37. Adechlorin, a new adenosine deaminase inhibitor containing chlorine production, isolation and properties. Synonyms: 2'-Chloropentostatin; 2'-Cldcf; 2'-Chloro-2'-deoxycoformycin. Grade: >98%. CAS No. 96328-17-5. Molecular formula: C11H15ClN4O4. Mole weight: 302.71.
Adecypenol
Adecypenol is an adenosine deaminase inhibitor produced from Streptomyces sp. OM-3223. Synonyms: Antibiotic OM 3223; 3-Cyclopentene-1,2-diol, 5-(7,8-dihydro-8-hydroxyimidazo(4,5-d)(1,3)diazepin-3(4H)-yl)-3-(hydroxymethyl)-. Grade: >98%. CAS No. 104493-13-2. Molecular formula: C12H16N4O4. Mole weight: 280.28.
Adenomycin
Adenomycin is a nucleoside antibiotic produced from Streptomyces griseoflavus C 19-97. Adenomycin has anti-gram-positive bacteria, negative bacteria, and tumor activity. Synonyms: NSC336242; [(1R,2S,3S,4S,5R,6R)-4-[(2R,3S,4R,5S,6S)-3-amino-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy]-3,5-dihydroxy-6-sulfooxycyclohexyl] (2S)-2-amino-3-hydroxypropanoate; (R)-2-Amino-3-hydroxy-propionic acid 4-(3-amino-4,5-dihydroxy-6-hydroxymethyltetrahydro-pyran-2-yloxy)-2-[5-(6-aminopurin-9-yl)-3,4-dihydroxytetrahydro-furan-2-ylmethoxy]-3,5-dihydroxy-6-sulfooxycyclohexyl ester. CAS No. 76174-56-6. Molecular formula: C25H39N7O18S. Mole weight: 757.68.
Adenophostin A
Adenophostin A is an inositol-1,4,5-triphosphate receptor antagonist produced from Penicillurn brevicompactum SANK 11991. Adenophostin is a potent inositol trisphosphate (IP3) receptor agonist. Synonyms: 2'-Adenylic acid, 3'-O-(3,4-di-O-phosphono-alpha-D-glucopyranosyl)-. Grade: >95%. CAS No. 149091-92-9. Molecular formula: C16H26N5O18P3. Mole weight: 669.32.
Adenophostin B
Adenophostin B is an inositol-1,4,5-triphosphate receptor antagonist produced from Penicillurn brevicompactum SANK 11991. Adenophostin is a potent inositol trisphosphate (IP3) receptor agonist. CAS No. 149091-93-0. Molecular formula: C18H28N5O19P3. Mole weight: 711.36.
Adiposin 1
Adiposin 1 is a metabolite of Streptomyces calvus TM-521 and Str.sp.A2396. Adiposin has anti-gram-positive bacteria, negative bacteria, plant pathogenic fungi activity, and has a strong inhibitory effect on alpha-amylase. Synonyms: Adiposin-1. Molecular formula: C19H33NO14. Mole weight: 499.46.
Adiposin 2
Adiposin 2 is a metabolite of Streptomyces calvus TM-521 and Str.sp.A2396. Adiposin has anti-gram-positive bacteria, negative bacteria, plant pathogenic fungi activity, and has a strong inhibitory effect on alpha-amylase. Synonyms: D-Glucose, O-4-deoxy-4-((4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl)amino)-alpha-D-glucopyranosyl-(1-4)-O-alpha-D-glucopyranosyl-(1-4)-, (1S-(1-alpha,4-alpha,5-beta,6-alpha))-; Adiposin-2. CAS No. 83764-12-9. Molecular formula: C25H43NO19. Mole weight: 661.60.
Adipostatin B
Adipostatin is a glycerol-3-phosphate dehydrogenase inhibitor produced in Streptornyces cyaneus 2299-SVI. Adipostatin B is an inhibitor of glycerol-3-phosphate dehydrogenase. Synonyms: 5-Isopentadecylresorcinol; 5-n-isopentadecylresorcinol. CAS No. 144284-17-3. Molecular formula: C21H36O2. Mole weight: 320.51.
Adustin
Akrabicin is an antibiotic produced in Streptomyces galactis against yeast and tinea mold. Synonyms: (3-Hydroxy-2-furanyl)phenylmethanone; Methanone, (3-hydroxy-2-furanyl)phenyl-; (2E)-2-[hydroxy(phenyl)methylidene]furan-3-one; 2-Benzoyl-3-hydroxyfuran. CAS No. 69579-74-4. Molecular formula: C11H8O3. Mole weight: 188.18.
Adxanthromycin A
Adxanthromycin A, a new inhibitor of ICAM-1/LFA-1 mediated cell adhesion from Streptomyces sp. NA-148. Molecular formula: C42H40O17. Mole weight: 816.76.
Adxanthromycin B
Adxanthromycin B, a new inhibitor of ICAM-1/LFA-1 mediated cell adhesion from Streptomyces sp. NA-148. Molecular formula: C48H50O22. Mole weight: 978.90.
Aerobactin
Akrabicin is a siderophore produced by the culture of Aerobacter aerogenes, Escherichia coli and Klebsiella pneumoniae under iron deficiency. Synonyms: Ferric-aerobactin; 3,9,15,21-Tetraazatricosane-8,12,16-tricarboxylic acid, 3,12,21-trihydroxy-2,10,14,22-tetraoxo-, [S-(R*,R*)]-. CAS No. 26198-65-2. Molecular formula: C22H36N4O13. Mole weight: 564.54.
Aerocavin
Aerocavin is a macrolide antibiotic produced in Chromobacterium violaceum. Aerocavin has anti-Gram-positive bacteria and weak anti-negative bacteria activity. Synonyms: Oxacyclotetradeca-3,6,9-triene-4-acetic acid, 12-hydroxy-14-(2-hydroxyundecyl)-10-methyl-2-oxo-, (3E,6E,9E,12R*,14S*(R*))-(+)-; 2-[(3E,6Z,9Z,12R,14S)-12-hydroxy-14-[(2R)-2-hydroxyundecyl]-10-methyl-2-oxo-1-oxacyclotetradeca-3,6,9-trien-4-yl]acetic acid. CAS No. 113702-00-4. Molecular formula: C27H44O6. Mole weight: 464.63.
Aerocyanidin
Aerocyanidin is an antibiotic produced in Chromobacterium violaceum. Aerocyanidin has strong anti-Gram-positive quotient activity, weak effect on negative bacteria. Synonyms: 11-(3-isocyano-3-methyloxiran-2-yl)undecaneperoxoic acid; kappa-Hydroxy-3-isocyano-3-methyloxiraneundecanoic acid (2-alpha(R*),3-alpha)-(-)-; Oxiraneundecanoic acid, kappa-hydroxy-3-isocyano-3-methyl-, (2-alpha(R*),3-alpha)-(-)-. Grade: >98%. CAS No. 113701-99-8. Molecular formula: C15H25NO4. Mole weight: 283.36.
(+)-Aeroplysinin-1
(+)-Aeroplysinin-1 is a metabolite originally isolated from the marine sponge V. aerophoba with diverse biological activity. It is a tertiary alcohol. Synonyms: NSC 170364; Aeroplysinin 1; (+)-shy-Aeroplysinin-1; (1S,6R)-3,5-Dibromo-1,6-dihydroxy-4-methoxy-2,4-cyclohexadiene-1-acetonitrile; Aeroplysinin; Aeroplysinin I; (1S-trans)-3,5-dibromo-1,6-dihydroxy-4-methoxy-2,4-cyclohexadiene-1-acetonitrile. Grade: ≥95%. CAS No. 28656-91-9. Molecular formula: C9H9Br2NO3. Mole weight: 338.98.
Aestivophoenin A
Aestivophoenin is a nerve cell protective substance produced in Streptomyces purpeofuscus. Aestivophoenin A can reduce the toxicity of L-glutamate to Nl8-RE-105 cells, with an ECso of 15.0 nmol/L, and has an antioxidant effect. CAS No. 171864-91-8. Molecular formula: C31H32N2O7. Mole weight: 544.59.
Aestivophoenin B
Aestivophoenin is a nerve cell protective substance produced in Streptomyces purpeofuscus. Aestivophoenin B can reduce the toxicity of L-glutamate to Nl8-RE-105 cells, with an ECso of 6.2 nmol/L, and has an antioxidant effect. CAS No. 171864-92-9. Molecular formula: C36H40N2O7. Mole weight: 612.71.
A-factor
It is produced by the strain of streptomyces griseus. It can not only promote the formation of spores and air hyphae by streptomycin, but also restore the ability of non-production mutants to produce streptomycin, which is the so-called Autoregulator. Synonyms: 2-Isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone; Q27144309; SCHEMBL6026457; DTXSID00965600; 4-(HYDROXYMETHYL)-3-(6-METHYLHEPTANOYL)OXOLAN-2-ONE; 2(3H)-Furanone, dihydro-4-(hydroxymethyl)-3-(6-methyl-1-oxoheptyl)-, (4R)-; (-)-A factor; (R)-4-Hydroxymethyl-3-(6-methyl-heptanoyl)-dihydro-furan-2-one. CAS No. 51311-41-2. Molecular formula: C13H22O4. Mole weight: 242.31.
Aflastatin A
It is produced by the strain of Streptomyces sp. MRI 142. Aflatoxin A has anti-Gram-positive bacteria, Pyricularia oryzae and yeast activity (MIC is 0.19-0.39 μg/mL), and inhibits the growth of adenocarcinoma 755 (1.0 mg/kg reduces tumor growth by 75% the above). Synonyms: 2,4-Pyrrolidinedione, 1,5-dimethyl-3-(1,8,9,11,13,15,17,19,21,23,25,27,28,29,30,31-hexadecahydroxy-2,4,6,10,12,14,18,20-octamethyl-32-(tetrahydro-3,4,5,6-tetrahydroxy-6-(2-hydroxyundecyl)-2H-pyran-2-yl)-2-dotriacontenylidene)-; LS-137668. Grade: ≥ 95%. CAS No. 179729-59-0. Molecular formula: C62H115NO24. Mole weight: 1258.56.
Aflatoxicol
The 2 ppm acetonitrile solution of aflatoxicol, a metabolite of aflatoxin, could be commonly used as a standard solution. Uses: Only to be used as a reference standard in analytical laboratories. Synonyms: Aflatoxin Ro; (1S-(1alpha,6abeta,9abeta))-2,3,6a,9a-Tetrahydro-1-hydroxy-4-methoxycyclopenta(c)furo(3',2':4,5)furo(2,3-h)(1)benzopyran-11(1H)-one; Cyclopenta(c)furo(3',2':4,5)furo(2,3-h)(1)benzopyran-11(1H)-one, 2,3,6a,9a-tetrahydro-1-hydroxy-4-methoxy-, (1S,6aR,9aS)-; AFL. Grade: ≥98%. CAS No. 29611-03-8. Molecular formula: C17H14O6. Mole weight: 314.29.
Aflatoxin G1
It is produced by the strain of Aspergillus flavus, Asp. parasiticus. The compound of aflatoxin has the activity of anti-gram-positive bacteria, inhibits cell mitosis, has the effect of liver necrosis and carcinogenesis, and is a mycotoxin which contaminates food. Uses: Only to be used as a reference standard in analytical laboratories. Synonyms: AF G1; (7aR,cis)3,4,7a,10a-tetrahydro-5-methoxy-1H,12H-furo[3',2':4,5]furo[2,3-h]pyrano[3,4-c]chromene-1,12-dione; Aflatoxin G(1); AFLATOXIN G; Aflatoxin G1,Crystalline; 5-(methyloxy)-3,4,7a,10a-tetrahydro-1H,12H-furo[3',2':4,5]furo[2,3-h]pyrano[3,4-c]chromene-1,12-dione; 1H,12H-Furo[3',2':4,5]furo[2,3-h]pyrano[3,4-c][1]benzopyran-1,12-dione, 3,4,7a,10a-tetrahydro-5-methoxy-, (7aR-cis)-; HSDB 3411; CCRIS 14; HSDB 3455. Grade: ≥98%. CAS No. 1165-39-5. Molecular formula: C17H12O7. Mole weight: 328.27.
Aflatoxin G2
Aflatoxin G2 is a naturally occuring mycotoxin produced by various species of the mold Aspergillus, which can be found in legumes, corn, soybeans, rice, milk, and cheese. Synonyms: Dihydroaflatoxin G1; 5-Methoxy-3,4,7a,9,10,10a-hexahydro-1H,12H-furo[3',2':4,5]furo[2,3-H]pyrano[3,4-c]chromene-1,12-dione. Grade: >98%. CAS No. 7241-98-7. Molecular formula: C17H14O7. Mole weight: 330.29.
Aflatoxin M1
It is produced by the strain of Aspergillus flavus, Asp. parasiticus. The compound of aflatoxin has the activity of anti-gram-positive bacteria, inhibits cell mitosis, has the effect of liver necrosis and carcinogenesis, and is a mycotoxin which contaminates food. Synonyms: AFLATOXIN M1; 4-Hydroxyaflatoxin B1; 3020O28I3; CCRIS 15; (6aR,9aR)-9a-hydroxy-4-methoxy-2,3,6a,9a-tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene-1,11-dione; (6aR-cis)-2,3,6a,9a-tetrahydro-9a-hydroxy-4-methoxycyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione; CHEBI:78576; Cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione,2,3,6a,9a-tetrahydro-9a-hydroxy-4-methoxy-,(6ar,9ar)-. Grade: ≥95%. CAS No. 6795-23-9. Molecular formula: C17H12O7. Mole weight: 328.27.
Aflatoxin Q1
Aflatoxin Q1 is a metabolite of Aflatoxin B1. It is created in human body as a in-vivo detoxification process of Aflatoxin B1. Uses: A metabolite of aflatoxin b1; a hepatocarcinogen in many animal models and probably a human carcinogen. it is produced by the predominant forms of cytochrome p 450 enzymes responsible for the biotransformation of afb1. it shows potential predictive value. Synonyms: Cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione, 2,3,6a,9a-tetrahydro-3-hydroxy-4-methoxy-, (3S,6aR,9aS)-; Cyclopenta(c)furo(3',2':4,5)furo(2,3-h)(1)benzopyran-1,11-dione, 2,3,6a,9a-tetrahydro-3-hydroxy-4-methoxy-, (3S-(3-alpha,6a-alpha,9a-alpha))-; (3S,6aR,9aS)-3-hydroxy-4-methoxy-2,3,6a,9a-tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene-1,11-dione. Grade: ≥98%. CAS No. 52819-96-2. Molecular formula: C17H12O7. Mole weight: 328.27.
Aflatrem
Aflatrem is the secondary metabolite of Aspergillus flavus. It is able to induce degeneration of neuronal processes in hippocampal neurotransmitter systems at low dose. It potentiates the gamma-aminobutyric acid (GABA)-induced chloride current. It is a tremorgenic mycotoxin with acute neurotoxic effect. Synonyms: 4H-3,15a-Epoxy-1-benzoxepino[6',7':6,7]indeno[1,2-b]indol-4-one, 9-(1,1-dimethyl-2-propenyl)-2,3,5b,6,7,7a,8,13,13b,13c,14,15-dodecahydro-5b-hydroxy-2,2,13b,13c-tetramethyl-, (3R,5bS,7aS,13bS,13cR,15aS)-; 9-(1,1-Dimethyl-2-propenyl)-2,3,5b,6,7,7aα,8,13,13b,13c,14,15-dodecahydro-5bβ-hydroxy-2,2,13bβ,13cα-tetramethyl-4H-3β,15aβ-epoxy-1-benzoxepino[6',7':6,7]indeno[1,2-b]indol-4-one; α,α-dimethylallylpaspalinine. Grade: 98.0%. CAS No. 70553-75-2. Molecular formula: C32H39NO4. Mole weight: 501.66.
Aflavarin
Aflavarin is a metabolite of the Sclerotia of Aspergillus flavus displaying anti-insectan activity against the fungivorous beetle Carpopbilus bemipterus. Synonyms: (3,8'-Bi-2H-1-benzopyran)-2,2'-dione, 5-(hydroxymethyl)-4,4',7,7'-tetramethoxy-5'-methyl-, (-)-; (-)-5-(Hydroxymethyl)-4,4',7,7'-tetramethoxy-5'-methyl[3,8'-bi-2H-1-benzopyran]-2,2'-dione. Grade: 98.0%. CAS No. 144429-67-4. Molecular formula: C24H22O9. Mole weight: 454.43.
Afragilimycin A
It is produced by the strain of Streptomyces neohygroscopicus sub-sp, afragilimycetius 19255. It has anti-gram-positive bacteria and anti-gram-negative bacteria including anaerobic bacteria activity. Synonyms: Afrigilimycin A; (2S)-4-[(2E,4E,6R)-6-[(1S,2S,3R,5S,6R)-2,5-dimethylspiro[4,9-dioxabicyclo[3.3.1]non-7-ene-6,2'-oxirane]-3-yl]-4-methylhepta-2,4-dienoyl]-1-[(5S,6S)-5-hydroxy-6-methyloxan-2-yl]-2-[(2S)-1-(methylamino)-1-oxopropan-2-yl]-3-oxo-2H-pyrrol-5-olate. CAS No. 76559-69-8. Molecular formula: C32H43N2O9-. Mole weight: 599.69.
Aggreceride A
It is produced by the strain of Streptomyces sp. OM-3209. Aggreceride had no antibacterial activity. Aggreceride A of 50 ?/ml inhibited thrombin-induced platelet aggregation of 92%. Aggreceride A of 25 ?/ml inhibited thrombin-induced platelet aggregation of 81%. Synonyms: S3L0ID00Y9; 2,3-Dihydroxypropyl 12-methyltetradecanoate; Tetradecanoic acid, 12-methyl-, 2,3-dihydroxypropyl ester; CTK4E0886; DTXSID50172766; (S)-12-Methyltetradecanoic acid (R)-2,3-dihydroxypropyl ester; Tetradecanoic acid,12-methyl-, (2R)-2,3-dihydroxypropyl ester, (12S)-. CAS No. 19207-26-2. Molecular formula: C18H36O4. Mole weight: 316.47.
Aggreceride B
It is produced by the strain of Streptomyces sp. OM-3209. Aggreceride had no antibacterial activity. Synonyms: 2,3-Dihydroxypropyl 14-methylpentadecanoate; Pentadecanoic acid, 14-methyl-, 2,3-dihydroxypropyl ester; Pentadecanoic acid,14-methyl-, 2,3-dihydroxypropyl ester (9CI); SCHEMBL17866968; CTK4A3241; DTXSID20909142. CAS No. 104700-85-8. Molecular formula: C19H38O4. Mole weight: 330.50.
Aggreceride C
It is produced by the strain of Streptomyces sp. OM-3209. Aggreceride had no antibacterial activity. Synonyms: 2,3-Dihydroxypropyl 15-methylhexadecanoate; Hexadecanoic acid, 15-methyl-, 2,3-dihydroxypropyl ester; SCHEMBL17866841; DTXSID80909143; LS-74852. CAS No. 104700-86-9. Molecular formula: C20H40O4. Mole weight: 344.53.
AGI-B4
AGI-B4 is a substance produced by Aspergillus sp. Y80118 that inhibits the growth of endothelial cells. It inhibits the proliferation of human umbilical vein endothelial cells (HUVECs) induced by vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF) and endothelial cell growth factor (ECGS) with IC50 of 1.4 μmol/ L, 2.8 μmol/L and 6.2 μmol/L. Synonyms: (7R,8R)-AGI-B4. CAS No. 1313588-44-1. Molecular formula: C16H14O7. Mole weight: 318.28.
Agrobactin
It is produced by the strain of Agrobacterium tume faciens. It's a ferric ion carrier. Synonyms: Ferriagrobactin; N-(3-(2,3-Dihydroxybenzamido)propyl)-N-(4-(2,3- dihydroxybenzamido)butyl)-2-(2,3-dihydroxyphenyl)- trans-5-methyl-oxazoline-4-carboxamide; 4-Oxazolecarboxamide, N-(4-((2,3-dihydroxybenzoyl)amino)butyl)-N-(3-((2,3-dihydroxybenzoyl)amino)propyl)-2-(2,3-dihydroxyphenyl)-4,5-dihydro-5-methyl-, (4S-trans)-; (2Z,4S,5R)-N-[4-[(2,3-dihydroxybenzoyl)amino]butyl]-N-[3-[(2,3-dihydroxybenzoyl)amino]propyl]-2-(5-hydroxy-6-oxocyclohexa-2,4-dien-1-ylidene)-5-methyl-1,3-oxazolidine-4-carboxamide; L-Agrobactin. Grade: 95%. CAS No. 70393-50-9. Molecular formula: C32H36N4O10. Mole weight: 636.65.
Agrochelin
It is produced by the strain of Agrobacterium sp. ALET-304. The IC50 of soil bactericin against P-388 was 0.053 ?ol/L, and the IC50 of cell a1-549, HT-29 and MEL 38 was between 0.107-0.268 ?ol/L. Synonyms: (3S)-3-hydroxy-3-{(2S,4R)-2-[(4R)-2-(2-hydroxy-6-pentylphenyl)-4,5-dihydro-1,3-thiazol-4-yl]-3-methyl-1,3-thiazolidin-4-yl}-2,2-dimethylpropanoic acid; CHEBI:65375; Q27133819. Molecular formula: C23H34N2O4S2. Mole weight: 466.66.
Agrocin 84
It is produced by the strain of Agrobacterium radiobacter. It can inhibit DNA synthesis, and sterilize Agrobacterium Tume Faciens. Synonyms: Agrocin; D-Glucofuranose,1-[hydrogen[9-[3-deoxy-5-O-[[(4,5-dideoxy-4-methyl-D-threo-pentonoyl)amino]hydroxyphosphinyl]-b-D-threo-pentofuranosyl]-9H-purin-6-yl]phosphoramidate]; Mono-D-glucofuranosyl[9-[3-deoxy-5-O-[[(4,5-dideoxy-4-methyl-D-threo-pentonoyl)amino]hydroxyphosphinyl]-b-D-threo-pentofuranosyl]-9H-purin-6-yl]phosphoramidate. CAS No. 59111-78-3. Molecular formula: C22H36N6O16P2. Mole weight: 702.50.
AH-1763 IIa
AH-1763 la is an antibiotic produced by Streptomyces cyaneus against herpes virus. Its ED50 against herpes simplex virus type 1 (HSV-1) is 2.1 μg/mL, and its IC50 against Vero cells is 15.2 μg/mL. Molecular formula: C22H18O6. Mole weight: 378.37.
Aibellin
It is produced by the strain of Vertocimonos poriurn ellipticum D1528. Alberin can enhance ruminant stomach fermentation, increase propionate production and reduce methane production caused by microorganisms in the stomach. Synonyms: AlamethicinI,2-L-alanine-9-L-phenylalanine-12-(2-methylalanine)-19-[N-[1-[[(2-hydroxyethyl)amino]methyl]-2-phenylethyl]-L-a-glutamine]-; L-a-Glutamine,N-acetyl-2-methylalanyl-L-alanyl-2-methylalanyl-L-alanyl-2-methylalanyl-L-alanyl-L-glutaminyl-2-methylalanyl-L-phenylalanyl-2-methylalanylglycyl-2-methylalanyl-2-methylalanyl-L-prolyl-L-valyl-2-methylalanyl-2-methylalanyl-L-a-glutamyl-N-[1-[[(2-hydroxyethyl)amino]methyl]-2-phenylethyl]-,(S)-. CAS No. 151036-29-2. Molecular formula: C94H147N21O27. Mole weight: 2003.29.
AJI-9561
AJI-9561 is a benzoxazole derivative produced by Streptomyces sp. AJ9561. It has cytotoxic activity with IC50 of 0.88 μmol/L and 1.63 μmol/L for Jorkat and P388 cells, respectively. Its mechanism of action is the same as that of UK-1, which can inhibit DNA topoisomerase U. Synonyms: (2,4'-Bibenzoxazole)-4-carboxylic acid, 2'-(2-hydroxy-6-methylphenyl)-. CAS No. 339300-34-4. Molecular formula: C22H14N2O5. Mole weight: 386.36.
Aklavin
It is produced by the strain of Streptomyces galilaeus. It has the activity of resisting gram positive bacterium, negative bacterium, candida and ringworm. Synonyms: Aclacinomycin T; 1-Deoxypyrromycin; Aclacinomycin; Doxypyrromycin; NSC 100290; CHEBI:74351; 1-Naphthacenecarboxylic acid, 2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-6,11-dioxo-4-((2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexapyranosyl)oxy)-, methyl ester, (1R-(1-alpha,2-beta,4-beta))-; aklavine. CAS No. 60504-57-6. Molecular formula: C30H35NO10. Mole weight: 569.60.
Aklavinone
Aklavinone is an anthracycline drug with an antitumor effect. CAS No. 16234-96-1. Molecular formula: C22H20O8. Mole weight: 412.39.
Akrobomycin
It is produced by the strain of Actinomadura reseoviolacea 129-AVI. It has anti-gram-negative bacteria, ringworm and tumor activity. Synonyms: 9,10-Anhydro-13-deoxocarminomycin; 5,12-Naphthacenedione, 10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-8-ethyl-9,10-dihydro-1,6,11-trihydroxy-, (S)-; DTXSID601008673; LS-94000; 3-Ethyl-5,10,12-trihydroxy-6,11-dioxo-1,2,6,11-tetrahydrotetracen-1-yl 3-amino-2,3,6-trideoxyhexopyranoside; Akrobomycin; Rubomycin Q1. CAS No. 89156-94-5. Molecular formula: C26H27NO8. Mole weight: 481.49.
AK-toxin I
It is produced by the strain of Alternaria kikuchiana AS-1223. It's a plant toxin (especially for pear trees). Synonyms: CTK3E8898; (2E,4E,6E)-8-(2-acetamido-3-phenyl-butanoyl)oxy-8-(2-methyloxiran-2-yl)octa-2,4,6-trienoic Acid. Grade: 95%. CAS No. 85146-09-4. Molecular formula: C23H27NO6. Mole weight: 413.46.
AK-toxin ll
It is produced by the strain of Alternaria kikuchiana AS-1223. It's a plant toxin (especially for pear trees). Synonyms: L-Phenylalanine, N-acetyl-, 7-carboxy-1-(2-methyloxiranyl)-2,4,6-heptatrienyl ester, (2S-(2R*(1S*,2E,4Z,6E)))-. Grade: 95%. CAS No. 85146-10-7. Molecular formula: C22H25NO6. Mole weight: 399.44.
AL-072
AL072 is an antibiotic against Legionella produced by Strepyomyces sp. AL91. It has strong anti-legionella pneumophila activity. CAS No. 168482-44-8. Molecular formula: C41H76O5. Mole weight: 649.04.
Aladapcin
It is produced by the strain of Nocardia sp. SANK 60484. Alanine in 1-100 ?/kg can enhance the resistance of mice against experimental E. coli infection. Synonyms: SCHEMBL4061749; DTXSID90921412; N-{2-[(2,6-Diamino-1,7-dihydroxy-7-iminoheptylidene)amino]-1-hydroxypropylidene}alanine. Grade: 95%. CAS No. 114540-27-1. Molecular formula: C13H25N5O5. Mole weight: 331.37.
Alahopcin
It is produced by the strain of Streptamyces albulus subsp. ochra-gerus B-52653. It can resist gram-positive bacteria, negative bacteria and plant pathogenic fungi, and inhibit Collagen-Proline hydroxylase. Synonyms: (2S)-2-((S)-2-aminopropanamido)-2-(1,5-dihydroxy-2-oxopyrrolidin-3-yl)acetic acid; B-52653. Grade: 95%. CAS No. 82576-50-9. Molecular formula: C9H15N3O6. Mole weight: 261.23.
Alamethicin F50
It is a neutral linear peptaibol complex with potent antimicrobial activity, containing 20 amino acids with an acetyl and phenylalaninol termini, produced by trichoderma sp. It is an ionopohore, transporting ions through membranes and artificial lipid membrane. It forms voltage-dependent ion channels in lipid bilayer membranes. Synonyms: Alamethicin F; Alamethicin Rf 50; Atroviridin A; 18-L-Glutamine-alamethicin I; Ac-Aib-Pro-Aib-Ala-Aib-Ala-Gln-Aib-Val-Aib-Gly-Leu-Aib-Pro-Val-Aib-Aib-D-Gln-D-Gln-Phe-ol. Grade: >98% by HPLC. CAS No. 56165-93-6. Molecular formula: C92H151N23O24. Mole weight: 1963.32.
Alanosine
It is produced by the strain of Streptomyces alanosinicus. It can inhibit adenine biosynthesis, resist yeast, dysentery morphosis, trichomonas vaginalis, inhibit neurotropic vaccinia virus and poliomyelitis virus, and also inhibit fibrosarcoma of transplanted ground mice. Synonyms: L-Alanosine; 3-(Hydroxynitrosoamino)-L-alanine; L-Alanine, 3-(hydroxynitrosoamino)-; L-2-Amino-3-(hydroxynitrosamino)propionic acid; Propionic acid, 2-amino-3-(hydroxynitrosamino)-, (L)-; (2S)-2-amino-3-[hydroxy(nitroso)amino]propanoic acid. Grade: 98%. CAS No. 5854-93-3. Molecular formula: C3H7N3O4. Mole weight: 149.11.
Alanylbactobolin
It is produced by the strain of Pseudomonas sp. BMG 13-A7. It has anti-gram-positive bacteria, negative bacteria and tumor activity. Synonyms: Bactobolin B; L-Alaninamide, L-alanyl-N-(3-(dichloromethyl)-3,4,4a,5,6,7-hexahydro-5,6,8-trihydroxy-3-methyl-1-oxo-1H-2-benzopyran-4-yl)-, (3S-(3-alpha,4-alpha,4a-beta,5-beta,6-alpha))-; DTXSID80995581; 5-Amino-2-{[3-(dichloromethyl)-1,5,6-trihydroxy-3-methyl-8-oxo-4,4a,5,6,7,8-hexahydro-3H-2-benzopyran-4-yl]amino}-4-oxohexanimidic acid. CAS No. 74141-68-7. Molecular formula: C17H25N3O7Cl2. Mole weight: 454.30.
Alanylclavam
Alanylclavam is a beta-lactam antibiotic produced by Streptomyces clavuligerus NRRL 3585. It is neither a substrate for nor inhibitor of several beta-lactamases, shows antimicrobial activity in defined minimal medium but little or no inhibitory activity in nutrient-rich medium. Synonyms: Ro-22-5417; 3-(7-Oxo-1-aza-4-oxabicyclo(3.2.0)hept-3-yl)alanine. CAS No. 74758-63-7. Molecular formula: C8H12N2O4. Mole weight: 200.19.
Alazopeptin
It is produced by the strain of Streptomyces griseoplanus. Corneas and Salmonella gallinarum were inhibited, and sarcoma cell 180 was moderately inhibited. Synonyms: L-Allyl-(6-diazo-5-oxo)-L-norleucyl-(6-diazo-5-oxo)-L-norleucine; Allyl-(6-diazo-5-oxo)-norleucyl-(6-diazo-5-oxo)-norleucine; Allyl-(6-diazo-5-oxo)-L-norleucyl-(6-diazo-5-oxo)-L-norleucine; (Z)-6-[[(Z)-1-carboxy-5-diazonio-4-oxidopent-4-enyl]amino]-1-diazonio-6-oxo-5-(prop-2-enylamino)hex-1-en-2-olate; Ambomycin; Alazopeptin(6CI,7CI,8CI); Norleucine, 6-diazo-5-oxo-N-2-propenylnorleucyl-6-diazo-5-oxo-(9CI). Grade: 99%. CAS No. 1397-84-8. Molecular formula: C15H20N6O5. Mole weight: 364.36.
Albaflavenone
It is produced by the strain of Streptomyces albido flavus. There was resistance to Bacillus thuringiensis with MIC 8-10 ?/mL. Synonyms: albaflavenone; (+)-epi-isozizaen-5-one; (3S,3aR,6S)-3,7,7,8-tetramethyl-2,3,4,5,6,7-hexahydro-1H-3a,6-methanoazulen-1-one; CHEBI:51460; LMPR0103700006; C17954; Q27122616. Molecular formula: C15H22O. Mole weight: 218.33.
Albocycline
It is produced by the strain of Streptomyces bruneoriseus and Str. roseocinereus. It was mainly resistant to gram-positive bacteria, and the MIC of S. aureus Sitajima strain was 1.56-3.12 ?/mL. The mice were not killed by intraperitoneal injection of 1000 mg/kg. Synonyms: Albocycline; Ingramycin; CHEMBL4128170; BDBM50274417; MFCD01674465; LS-16246; J-015824; Oxacyclotetradeca-3,6,9-trien-2-one,5-hydroxy-8-methoxy-5,9,13,14-tetramethyl-, (3E,5R,6E,8S,9E,13S,14R)-. Grade: 95%. CAS No. 25129-91-3. Molecular formula: C18H28O4. Mole weight: 308.41.
Albocycline K3
It is produced by the strain of Streptomyces sp. OH-3984. The concentration of B16 melanoma cells was 15.0 ?/mL, and there was no cytotoxic activity under this concentration. Molecular formula: C17H28O4. Mole weight: 296.40.
Albocycline M-1
It is produced by the strain of Streptomyces bruneogriseus MCRL 0129. It has very weak anti-gram-negative bacterial activity. Molecular formula: C18H28O5. Mole weight: 324.41.
Albocycline M-2
It is produced by the strain of Streptomyces bruneogriseus MCRL 0129. It has very weak anti-gram-negative bacterial activity. Molecular formula: C17H28O5. Mole weight: 312.40.
Albomycin δ1
It is produced by the strain of Streptomyces subtropicus. It has anti-gram-positive and negative bacterial activities. The iron was removed with hydroxyquinoline, and the antibacterial activity disappeared. The FeCl3 solution was added to restore the activity completely. Synonyms: albomycin delta(1); CHEBI:83206; [N(5)-acetyl-N(5)-(hydroxy-kappaO)-L-ornithyl-N(5)-acetyl-N(5)-(hydroxy-kappaO)-L-ornithyl-N(5)-acetyl-N(5)-(hydroxy-kappaO)-L-ornithyl-L-seryl-(3S)-3-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrothiophen-2-yl]-D-serinato(3-)]iron; iron(3+) N(5)-acetyl-N(5)-oxido-L-ornithyl-N(5)-acetyl-N(5)-oxido-L-ornithyl-N(5)-acetyl-N(5)-oxido-L-ornithyl-L-seryl-(3S)-3-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrothiophen-2-yl]-D-serine. CAS No. 1414-39-7. Molecular formula: C36H58FeN10O18S3+. Mole weight: 1006.81.
Albomycin δ2
It is produced by the strain of Streptomyces subtropicus. It has anti-gram-positive and negative bacterial activities. The iron was removed with hydroxyquinoline, and the antibacterial activity disappeared. The FeCl3 solution was added to restore the activity completely. Synonyms: albomycin delta(2); CHEBI:83215; [N(5)-acetyl-N(5)-(hydroxy-kappaO)-L-ornithyl-N(5)-acetyl-N(5)-(hydroxy-kappaO)-L-ornithyl-N(5)-acetyl-N(5)-(hydroxy-kappaO)-L-ornithyl-L-seryl-(3S)-3-{(2R,3R,4R,5R)-5-[4-(carbamoylimino)-3-methyl-2-oxo-3,4-dihydropyrimidin-1(2H)-yl]-3,4-dihydroxytetrahydrothiophen-2-yl}-D-serinato(3-)]iron; iron(3+) N(5)-acetyl-N(5)-oxido-L-ornithyl-N(5)-acetyl-N(5)-oxido-L-ornithyl-N(5)-acetyl-N(5)-oxido-L-ornithyl-L-seryl-(3S)-3-{(2R,3R,4R,5R)-5-[4-(carbamoylimino)-3-methyl-2-oxo-3,4-dihydropyrimidin-1(2H)-yl]-3,4-dihydroxytetrahydrothiophen-2-yl}-D-serine. Molecular formula: C37H60FeN12O18S3+. Mole weight: 1048.85.
Albomycin epsilon
It is produced by the strain of Streptomyces subtropicus. It has anti-gram-positive and negative bacterial activities. The iron was removed with hydroxyquinoline, and the antibacterial activity disappeared. The FeCl3 solution was added to restore the activity completely. Synonyms: 2FI7OQF5OS; Q27156693. CAS No. 12676-10-7. Molecular formula: C36H56FeN11O17S. Mole weight: 1002.80.
Albonoursin
It is produced by the strain of Streptomyces noursei and Str. albus var fungatus. It has the activity of anti-gram-positive bacteria and some gram-negative bacteria. Synonyms: Albonoursine; Albonursin; cyclo(DeltaPhe-DeltaLeu); 3-Benzylidene-6-isobutylidene-2,5-dioxopiperazine; cyclo(dehydroleucyl-dehydrophenylalanyl); CHEBI:71609; 2,5-Piperazinedione, 3-(2-methylpropylidene)-6-(phenylmethylene)-, (Z,Z)-. Grade: 99%. CAS No. 1222-90-8. Molecular formula: C15H16N2O2. Mole weight: 256.30.
Albothricin
It is produced by the strain of SIPl-2985. It has anti-gram positive bacteria and negative bacteria activity, but has no effect on enterococcus faecalis and pseudomonas aeruginosa. Synonyms: [5-(3,6-diaminohexanoylamino)-3-hydroxy-2-(hydroxymethyl)-6-[(5-methyl-4-oxo-3a,6,7,7a-tetrahydro-1H-imidazo[4,5-c]pyridin-2-yl)amino]oxan-4-yl] carbamate; 4H-Imidazo(4,5-c)pyridin-4-one, 2-((4-O-(aminocarbonyl)-2-deoxy-2-((3,6-diamino-1-oxohexyl)amino)-beta-D-gulopyranosyl)amino)-1,3a,5,6,7,7a-hexahydro-5-methyl-, (3aS-(2(R*),3aalpha,7abeta))-. Grade: 95%. CAS No. 103867-06-7. Molecular formula: C20H36N8O7. Mole weight: 500.55.
Albrassitriol
It is a metabolite of Alternaria brassiae. Synonyms: (1R-(1alpha,4alpha,4aalpha,8abeta))-1,4,4a,5,6,7,8,8a-Octahydro-1-(hydroxymethyl)-2,5,5,8a-tetramethyl-1,4-naphthalenediol; 1,4-Naphthalenediol, 1,4,4a,5,6,7,8,8a-octahydro-1-(hydroxymethyl)-2,5,5,8a-tetramethyl-, (1R-(1alpha,4alpha,4aalpha,8abeta))-. Grade: ≥98%. CAS No. 110557-39-6. Molecular formula: C15H26O3. Mole weight: 254.37.
Alcindoromycin
It is produced by the strain of Actinosporangium sp. C36145. It has anti-gram-positive bacteria and anti-tumor effect. Synonyms: 1-Naphthacenecarboxylic acid, 1,2,3,4,6,11-hexahydro-4-((O-2,6-dideoxy-alpha-L-lyxo-hexopyranosyl-(1-4)-O-2,6-dideoxy-alpha-L-lyxo-hexopyranosyl-(1-4)-2,3,6-trideoxy-3-(methylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-6,11-dioxo-2-ethyl-2,5,7,10-tetrahydroxy-, methyl ester, (1R-(1-alpha,2-beta,4-beta))-; DTXSID10993434; NSC304415; NSC-304415. Grade: 98%. CAS No. 72586-21-1. Molecular formula: C41H53NO17. Mole weight: 831.85.
Aldecalmycin
It is produced by the strain of Streptomyces sp. MJ147-72F6. Anti-gram-positive bacteria activity, anti-sensitive Staphylococcus aureus and methicillin-resistant Staphylococcus aureus (MRSA) activity is the same. MIC: 6.25-25 ?/mL. Synonyms: 3-[(1R,2S,4aR,6S,8R,8aS)-2-[(E,2S,3R,4S)-4-hydroxy-3,5-dimethyl-2-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoct-5-enyl]-1,3,6,8-tetramethyl-4a,5,6,7,8,8a-hexahydro-2H-naphthalen-1-yl]-3-oxopropanal; 1-Naphthalenepropanal, 2-[(2S,3R,4S,5E)-2-(b-D-glucopyranosyloxy)-4-hydroxy-3,5-dimethyl-5-octenyl]-1,2,4a,5,6,7,8,8a-octahydro-1,3,6,8-tetramethyl-b-oxo-, (1R,2S,4aR,6S,8R,8aS)-. Grade: 95%. CAS No. 139953-58-5. Molecular formula: C33H54O9. Mole weight: 594.77.
Aldgamycin F
It is produced by the strain of Streptomyces lavendulae and Str. avidinii. The anti-gram-positive bacteria activity of G was stronger than that of F, and the anti-Staphylococcus aureus activity was similar to that of xiramycin. CAS No. 55141-41-8. Molecular formula: C37H56O16. Mole weight: 756.83.
Aldgamycin G
It is produced by the strain of Streptomyces lavendulae and Str. avidinii. The anti-gram-positive bacteria activity of G was stronger than that of F, and the anti-Staphylococcus aureus activity was similar to that of xiramycin. Synonyms: 8-Deoxyaldgamycin F; Aldgamycin G; Aldgamycin F, 8-deoxy-; LS-16283; (6Z,14Z)-2-(((5-hydroxy-3,4-dimethoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)-9-((6-hydroxy-4,9-dimethyl-2-oxo-1,3,8-trioxaspiro[4.5]decan-7-yl)oxy)-3,8,10,12-tetramethyl-4,17-dioxabicyclo[14.1.0]heptadeca-6,14-diene-5,13-dione; 1,3,8-Trioxaspiro[4.5]decane, aldgamycin F deriv.; 4,17-Dioxabicyclo[14.1.0]heptadecane, aldgamycin F deriv. Grade: 95%. CAS No. 107745-56-2. Molecular formula: C37H56O15. Mole weight: 740.83.
It is produced by the strain of Aleurodiscus mirabilis. At very low concentrations, Mucor Mie-Hei mycelia were abnormally divergent. Synonyms: Cyclopenta(4,5)cyclooct(1,2-f)indene-6-carboxaldehyde, 1,2,3,3a,4,6a,7,7a,8,9,10,10a,11,11a-tetradecahydro-10-(1-methylethyl)-3,7a,12-trimethyl-2-(beta-D-xylopyranosyloxy)-, (2S-(2-alpha,3-beta,3a-beta,6a-alpha,7a-alpha,10-beta,10a-beta,11a-beta))-. Grade: 95%. CAS No. 122535-46-0. Molecular formula: C30H46O6. Mole weight: 502.68.
Alisamycin
It is produced by the strain of Streptomyces actuosus (Str. sp. Y-8831582). It has anti-gram-positive bacteria, Candida and other fungi activity, and also has weak inhibition of L1210 leukemia cell activity. Synonyms: 2,4,6-Heptatrienamide, 7-(4-((5-cyclohexyl-1-oxo-2,4-pentadienyl)amino)-2-hydroxy-5-oxo-7-oxabicyclo(4.1.0)hept-3-en-2-yl)-N-(2-hydroxy-5-oxo-1-cyclopenten-1-yl)-; 2,4,6-Heptatrienamide,7-[(1S,2R,6R)-4-[[(2E,4E)-5-cyclohexyl-1-oxo-2,4-pentadienyl]amino]-2-hydroxy-5-oxo-7-oxabicyclo[4.1.0]hept-3-en-2-yl]-N-(2-hydroxy-5-oxo-1-cyclopenten-1-yl)-,(2E,4E,6E)-(9CI); 7-Oxabicyclo[4.1.0]heptane, 2,4,6-heptatrienamidederiv.; (-)-Alisamycin. Grade: 95%. CAS No. 136398-54-4. Molecular formula: C29H32N2O7. Mole weight: 520.57.