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γ-2-MSH (41-58), amide is isolated from γ-2-MSH which is derived from the N-terminal fragment of proopiomelanocortin (POMC) and contains the His-Phe-Arg-Trp motif common to all melanocortin endogenous agonist ligands. Synonyms: H-Tyr-Val-Met-Gly-His-Phe-Arg-Trp-Asp-Arg-Phe-Gly-NH2; Gamma-2-MSH (41-58), amide. CAS No. 799841-81-9. Molecular formula: C74H100N22O15S. Mole weight: 1569.79.
γ-Chloronorvaline is produced by the strain of Streptomyces griseosporeus AL-719. It has the activity of resistance to Pseudomonas aeruginosa, Serrata, Klebsiella pneumoniae and Bacillus subtilis in the synthetic medium, but has no effect on Escherichia coli. Synonyms: gamma-Chloronorvaline; Antibiotic AL 719. CAS No. 76265-38-8. Molecular formula: C5H10ClNO2. Mole weight: 151.59.
gamma-Glutamylasparagine is a dipeptide composed of gamma-glutamate and asparagine. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: L-Asparagine, L-γ-glutamyl-; L-gamma-glutamyl-L-asparagine; GEN dipeptide; GGlu-Asn; Glutamyl-asparagine; gamma-Glutamate Asparagine dipeptide; γ-Glutamylasparagine; N5-((S)-3-amino-1-carboxy-3-oxopropyl)-L-glutamine. Grade: ≥98%. CAS No. 38681-07-1. Molecular formula: C9H15N3O6. Mole weight: 261.23.
gamma-Glutamyl-isoleucine
gamma-Glutamyl-isoleucine is a dipeptide composed of glutamate and isoleucine. Synonyms: L-Glutamyl-L-Isoleucine; Glu-Ile. CAS No. 23632-83-9. Molecular formula: C11H20N2O5. Mole weight: 260.29.
gamma-Glutamylproline
gamma-Glutamylproline is a dipeptide composed of gamma-glutamate and proline. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: L-Proline, L-γ-glutamyl-; N-γ-L-glutamyl-L-proline; (S)-1-((S)-4-Amino-4-carboxy-butyryl)-pyrrolidine-2-carboxylic acid; γ-(S)-Glutamyl-(S)-prolin; γ-Glutamylproline; L-γ-Glutamyl-L-proline; Glutamyl-proline; GEP dipeptide; GE-P dipeptide; ((S)-4-amino-4-carboxybutanoyl)-L-proline. Grade: ≥98%. CAS No. 53411-63-5. Molecular formula: C10H16N2O5. Mole weight: 244.24.
gamma-Glutamylserine
gamma-Glutamylserine is a dipeptide composed of gamma-glutamate and serine. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: L-Serine, L-γ-glutamyl-; L-gamma-glutamyl-L-serine; N5-((S)-1-carboxy-2-hydroxyethyl)-L-glutamine; G-Glu-Ser; gamma-Glutamyl-L-serine; GES dipeptide; (S)-2-Amino-5-[(S)-1-carboxy-2-hydroxyethylamino]-5-oxopentanoic acid; L-Ser-γ-L-Glu; γ-glutamylserine; γ-Glu-Ser; Glutamyl-serine. Grade: >98%. CAS No. 5875-35-4. Molecular formula: C8H14N2O6. Mole weight: 234.21.
gamma-Glutamylthreonine
gamma-Glutamylthreonine is a dipeptide composed of gamma-glutamate and threonine. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: L-gamma-glutamyl-L-threonine; Glutamyl-threonine; GET dipeptide; gammaGlu-Thr-OH; N5-((1S,2R)-1-carboxy-2-hydroxypropyl)-L-glutamine; L-gamma-Glu-L-Thr; γ-Glu-Thr; (2S)-2-amino-5-{[(1S,2R)-1-carboxy-2-hydroxypropyl]amino}-5-oxopentanoic acid. Grade: ≥95%. CAS No. 5652-48-2. Molecular formula: C9H16N2O6. Mole weight: 248.23.
γ-Hydroxymevinolin
γ-Hydroxymevinolin is a homolog of lovastatin produced by Aspergillus terreus MF-4833. It has anti-fungal, cholesterol and blood lipid-lowering activities. Synonyms: 3''-Hydroxylovastatin. CAS No. 125638-72-4. Molecular formula: C24H36O6. Mole weight: 420.54.
γ-Rubromycin is a quinone antibiotic originally isolated from Streptomyces. It is effective against Gram-positive bacteria. Synonyms: (S)-4,4',9,9'-Tetrahydro-5',8',10-trihydroxy-7'-methoxy-4',9',9-trioxospiro[benzo[1,2-b:5,4-c']dipyran-2(3H),2'(3'H)-naphtho[2,3-b]furan]-7-carboxylic acid methyl ester. Grade: ≥98%. CAS No. 27267-71-6. Molecular formula: C26H18O12. Mole weight: 522.41.
Ganoderic acid U is a substance isolated from Ganoderma lucidum with anti-tumor activity. Synonyms: (24E)-3α,7α-Dihydroxy-5α-lanosta-8,24-dien-26-oic acid. Grade: ≥98% by HPLC. CAS No. 86377-51-7. Molecular formula: C30H48O4. Mole weight: 472.70.
Ganoderic acid W
Ganoderic acid W is a substance isolated from Ganoderma lucidum with anti-tumor activity. Synonyms: (24E)-3α,15α-Di(acetyloxy)-7α-hydroxy-5α-lanosta-8,24-dien-26-oic acid. Grade: ≥98% by HPLC. CAS No. 86377-49-3. Molecular formula: C34H52O7. Mole weight: 572.77.
Ganoderic acid X
Ganoderic acid X is a substance isolated from Ganoderma lucidum with anti-tumor activity. Synonyms: 15alpha-Acetoxy-3alpha-hydroxy-5alpha-lanosta-7,9(11),24-trien-26-oic acid; (24E)-3α-Hydroxy-15α-acetoxylanosta-7,9(11),24-triene-26-oic acid. Grade: ≥98% by HPLC. CAS No. 86377-53-9. Molecular formula: C32H48O5. Mole weight: 512.72.
GE20372 A
GE20372 A, a tetrapeptide, is produced by the strain of Streptomyces sp. It is used as a human immunodeficiency virus (HIV-L) protease inhibitor. Synonyms: GE20372 Factor A; GE-20372A; (1(S),2(S))-N2-(((1-Carboxy-2-(4-hydroxyphenyl)ethyl)amino)carbonyl)-L-arginyl-N-(1-formyl-2-phenylethyl)-L-valinamide. CAS No. 163565-75-1. Molecular formula: C30H41N7O7. Mole weight: 611.69.
GE20372 B
GE20372 B is a tetrapeptide produced by the strain of Streptomyces sp. It is used as a human immunodeficiency virus (HIV-L) protease inhibitor. Molecular formula: C30H41N7O7. Mole weight: 611.69.
Gelastatin A
It is produced by the strain of Westerdykella multispora F50733. It can inhibit the activity of leucinase A and the IC50 of leucinase A is 0.63 μmol/L. Synonyms: (all-E)-5-(2,4-Hexadienylidene)-5,6-dihydro-2-oxo-2H-pyran-3-propanoic acid. Grade: ≥98%. Molecular formula: C14H16O4. Mole weight: 248.27.
Geninthiocin
A thiopeptide antibiotic isolated from a streptomyces sp.; a potent activator of the tipa gene; a bacterial transcription regulator involved in multidrug resistance; displays a 10-fold selectivity for bacteria over mammalian cells lines; closely related to siomycin, a recently discovered inhibitor of oncogenic transcription factor, foxm1. Synonyms: NSC676674; 14-Demethylberinamycin. Grade: >95% by HPLC. CAS No. 158792-27-9. Molecular formula: C50H49N15O15S. Mole weight: 1132.08.
Gentamycin B
Gentamycin B is an aminoglycoside antibiotic coproduced as a minor component in the gentamicin fermentation. It was found to have the same antibacterial spectrum as gentamicin in vitro and in vivo. Synonyms: Sch-14342; Sch 14342. Molecular formula: C19H38N4O10. Mole weight: 482.5.
Gerfelin
It is produced by the strain of Beauvaria felina QN 22047. Gerfelin inhibited GGPP synthase activity with IC50 of 3.5 g/mL. Synonyms: Benzoic acid, 4-(2,3-dihydroxy-5-methylphenoxy)-2-hydroxy-6-methyl-. CAS No. 627545-07-7. Molecular formula: C15H14O6. Mole weight: 290.27.
GERI-155
It is originally isolated from Streptomyces sp. GERI-155. GERI-155 had anti-Gram-positive bacteria (MIC 0.09-12.5 μg/mL) and some Gram-negative bacteria, such as Pseudomonas aeruginosa and Salmonella typhimurium activities. Molecular formula: C35H58O14. Mole weight: 702.82.
GERI-BP001 A
GERI-BP001 A is produced by the strain of Aspergillus fumigatus F37 with inhibitory activity against ACAT. Synonyms: GERI-BP-001A. Molecular formula: C27H33NO6. Mole weight: 467.55.
GERI-BP002-A
It is originally isolated from Aspergillus fumigatus F93. GERI-BP002-A inhibits ACTC with an IC50 of 50 μmol/L. Uses: Used as an antioxidant and stabilizer for polymers (abs, polypropylene, polyacetal, rubber, latex, and adhesives). Synonyms: Antioxidant 2246; Bisalkofen BP; 6,6'-Methylenebis(2-(tert-butyl)-4-methylphenol); Antioxidant BKF; Chemanox 21; Methylenebis; Plastanox 2246; NSC 7781; BRN 2062676. Grade: >99.0% by GC. CAS No. 119-47-1. Molecular formula: C23H32O2. Mole weight: 340.50.
Germicidin A
A pyranone isolated from streptomyces sp.; an extremely potent autoregulator of the sporulation of the producing strain, and spores of closely related species. Synonyms: (S)-6-(sec-butyl)-3-ethyl-4-hydroxy-2H-pyran-2-one. Grade: >95% by HPLC. CAS No. 151271-57-7. Molecular formula: C11H16O3. Mole weight: 196.24.
Germicidin B
A pyranone isolated from streptomyces sp.; a potent autoregulator of the sporulation of the producing strain, and spores of closely related species. Synonyms: 2H-Pyran-2-one, 3-ethyl-4-hydroxy-6-(1-methylethyl)-. Grade: >95% by HPLC. CAS No. 150973-78-7. Molecular formula: C10H14O3. Mole weight: 182.22.
GEX1Q1
It is originally isolated from Streptomyces sp. GEX1. GEX1Q1 has no antibacterial activity but has cytotoxicity to some cancer cells. Molecular formula: C25H42O7. Mole weight: 454.60.
GEX1Q2
It is originally isolated from Streptomyces sp. GEX1. GEX1Q2 has no antibacterial activity but has cytotoxicity to some cancer cells. Molecular formula: C25H42O7. Mole weight: 454.60.
GEX1Q3
It is originally isolated from Streptomyces sp. GEX1. GEX1Q3 has no antibacterial activity but has cytotoxicity to some cancer cells. Molecular formula: C31H50O12. Mole weight: 614.72.
Gibbestatin B
It is produced by the strain of Streptomyces sp. C39. Gibbestatin B inhibits the expression of α-amylase induced by gibberellin in De-embryoned rice and barley (IC50 is 25-50 ppm, IC100 is 100-200 ppm), and has no anti-bacterial, anti-yeast and anti-fungal effects at 100 ppm (MIC, agar dilution method using bouillon agar for bacteria and Sabouraud agar for yeast and fungi). Synonyms: Antibiotic 2-11-B. CAS No. 89687-34-3. Molecular formula: C22H26O6. Mole weight: 386.44.
Gibbestatin C
It is produced by the strain of Streptomyces sp. C39. It is a bioactive substance. Gibberellin C of 200 ppm has no inhibitory effect on α-amylase. It also has no anti-bacterial, anti-yeast and anti-fungal effects at 100 ppm (MIC, agar dilution method using bouillon agar for bacteria and Sabouraud agar for yeast and fungi). Synonyms: 2-Hydroxypenyl Gibbestatin B. Molecular formula: C28H30O7. Mole weight: 478.53.
Gilvocarcin E
It is produced by the strain of Streptomyces gilvotanareus, Str. anandii. It has anti-gram-positive bacterial activity and can inhibit sarcoma 180 and P388 leukemia cells. Synonyms: 8-Ethyl-4-(6-deoxy-α-L-galactofuranosyl)-1-hydroxy-10,12-dimethoxy-6H-benzo[d]naphtho[1,2-b]pyran-6-one; Anandimycin C; Toromycin C; dihydrotoromycin; 4-Fucofuranosyl-1-hydroxy-10,12-dimethoxy-8-ethyl-6H-benzo(d)naphtho(1,2b)pyran-6-one; 1,4-Anhydro-6-deoxy-1-(8-ethyl-1-hydroxy-10,12-dimethoxy-6-oxo-6H-benzo[d]naphtho[1,2-b]pyran-4-yl)hexitol. CAS No. 80937-34-4. Molecular formula: C27H28O9. Mole weight: 496.50.
Gilvusmycin
It is produced by the strain of Streptomyces sp. It is an antibiotic with strong anti-tumor activity. It can inhibit P388, K562, A431 and MKN28 cells with IC50 (ng/mL) of 0.08, 0.86, 0.72 and 0.75, respectively. Synonyms: 6-({6-[(6-acetyl-5-hydroxy-4-methoxy-3,6,7,8-tetrahydropyrrolo[3,2-e]indol-2-yl)carbonyl]-5-hydroxy-4-methoxy-3,6,7,8-tetrahydropyrrolo[3,2-e]indol-2-yl}carbonyl)-3-methyl-4,4a,5,6-tetrahydrocyclopropa[c]pyrrolo[3,2-e]indol-8(1H)-one. CAS No. 195052-09-6. Molecular formula: C38H34N6O8. Mole weight: 702.71.
Girolline
It is produced by the strain of Pseudaxinyssa cantharella. It can inhibit protein biosynthesis and has anti-tumor effect. Synonyms: Giracodazole; Girodazole; Giracodazolum; (alphaS)-2-Amino-alpha-((1S)-2-amino-1-chloroethyl)imidazole-4-methanol; (1S,2S)-1-(2-Amino-5-imidazolyl)-2-chloro-3-amino-1-propanol. Grade: 95%. CAS No. 110883-46-0. Molecular formula: C6H11ClN4O. Mole weight: 190.63.
Glidobactin A is an acyl peptide antibiotic produced by Pseudomonas sp. CB-3. It has activity against Candida, Aspergillus fumigatus and Trichophyton, but it is not effective against Candida albicans M-9 infection in mice. Synonyms: Cepafungin II. CAS No. 108351-50-4. Molecular formula: C27H44N4O6. Mole weight: 520.66.
Glidobactin B
It is produced by the strain of Polyangium brachysporum sp. No. K481-B-101. It is an anti-tumor antibiotic. It has the activity against pathogenic fungi and yeast, the activity of Glidobactin C is the strongest. It also extends the survival of mice inoculated with leukemia P388 cells. Synonyms: Antibiotic BU-2867TB; BU-2867TB; 2,4,8-Tetradecatrienamide, N-(2-hydroxy-1-(((10-hydroxy-5-methyl-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl)amino)carbonyl)propyl)-, (5S-(3E,5R*,8R*(1R*(2E,4E,8E),2S*),10R*))-. Grade: ≥95%. CAS No. 108351-51-5. Molecular formula: C29H46N4O6. Mole weight: 546.70.
Glidobactin C
It is produced by the strain of Polyangium brachysporum sp. No. K481-B-101. It is an anti-tumor antibiotic. It has the activity against pathogenic fungi and yeast, the activity of Glidobactin C is the strongest. Glidobactin C has anti-candida albicans and aspergillus fumigatus activity with MIC of 0.8 μg/mL. It also extends the survival of mice inoculated with leukemia P388 cells. Synonyms: Antibiotic BU-2867TC; BU-2867TC; 2,4-Tetradecadienamide, N-(2-hydroxy-1-(((10-hydroxy-5-methyl-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl)amino)carbonyl)propyl)-, (5S-(3E,5R*,8R*(1R*(2E,4E),2S*),10R*))-. Grade: ≥95%. CAS No. 108351-52-6. Molecular formula: C29H48N4O6. Mole weight: 548.72.
Glidobactin F
It is produced by the strain of Polyangium brachysporum sp. No. K481-B-101. It is an anti-tumor antibiotic. It has the activity against pathogenic fungi and yeast, the activity of Glidobactin C is the strongest. It also extends the survival of mice inoculated with leukemia P388 cells. Synonyms: Antibiotic BU 2867TF; Bu-2867TF; 2,4-Decadienamide, N-(2-hydroxy-1-(((10-hydroxy-5-methyl-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl)amino)carbonyl)propyl)-, (5S-(3E,5R*,8R*(1R*(2E,4E),2S*),10R*))-. Grade: ≥95%. CAS No. 119259-72-2. Molecular formula: C25H40N4O6. Mole weight: 492.61.
Glidobactin G
It is produced by the strain of Polyangium brachysporum sp. No. K481-B-101. It is an anti-tumor antibiotic. It has the activity against pathogenic fungi and yeast, the activity of Glidobactin C is the strongest. It also extends the survival of mice inoculated with leukemia P388 cells. Synonyms: Antibiotic BU 2867TG; Bu-2867TG; 2,4-Dodecadienamide, N-(2-hydroxy-1-(((10-hydroxy-5-(hydroxymethyl)-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl)amino)carbonyl)propyl)-, (5R-(3E,5R*,8S*(1S*(2E,4E),2R*),10S*))-. Grade: ≥95%. CAS No. 119259-71-1. Molecular formula: C27H44N4O7. Mole weight: 536.66.
Gliocladic acid
It is produced by the strain of Gliocladium virens SANK 12679, Chaetomium globosum SANK 13379, Trichoderma viride SANK 13479. It has anti-tumor activity. Synonyms: (E)-2-Hydroxymethyl-3-[3-(hydroxymethyl)-6alpha-(1-methylethyl)-2-cyclohexen-1beta-yl]propenoic acid. CAS No. 82425-48-7. Molecular formula: C14H22O4. Mole weight: 254.32.
Gliorosein
Gliorosein is a fungal metabolite produced by Gliocladium which is an asexual fungal genus in the Hypocreaceae. Gliorosein displays antibacterial activity against B. allii, B. subtilis and E. coli. Synonyms: 2,3-dimethoxy-5S,6S-dimethyl-2-cyclohexene-1,4-dione; 2-Cyclohexene-1,4-dione, 2,3-dimethoxy-5,6-dimethyl-, (5S-trans)-. Grade: ≥95%. CAS No. 4373-40-4. Molecular formula: C10H14O4. Mole weight: 198.22.
Gliotoxin
It is produced by the strain of Gliocladium fimbriatum, Trichoderma lignorum, Penicillum cineroscens. It has the activity of anti-gram positive bacterium, negative bacterium, fusarium oxysporum, endosporium, ringworm fungus and other fungi, and has the effect of inhibiting poliovirus. Uses: Immunosuppressive agents. Synonyms: Aspergillin; SN 12879; SN 12870; 10H-3,10a-Epidithiopyrazino(1,2-a)indole-1,4-dione,2,3,5a,6-tetrahydro-6-hydroxy-3-(hydroxymethyl)-2-methyl-; (3R,5aS,6S,10aR)-6-hydroxy-3-(hydroxymethyl)-2-methyl-2,3,5a,6-tetrahydro-10H-3,10a-epidithiopyrazino[1,2-a]indole-1,4-dion. Grade: >99% by HPLC. CAS No. 67-99-2. Molecular formula: C13H14N2O4S2. Mole weight: 326.39.
Glisoprenin A
It is produced by the strain of Gliocladium sp. FO-1513. It is a cholesterol acyltransferase (ACAT) inhibitor, and it can inhibit the formation of Appressorium on the hydrophobic surface of Magnaporthegrisea. Synonyms: (+)-GlisopreninA; FO 1513A; 2,6,10,14,34-Hexatriacontapentaene-1,19,23,27,31-pentol,3,7,11,15,19,23,27,31,35-nonamethyl-. Grade: 95%. CAS No. 144376-62-5. Molecular formula: C45H82O5. Mole weight: 703.14.
Glisoprenin B
It is produced by the strain of Gliocladium sp. FO-1513. It is a cholesterol acyltransferase (ACAT) inhibitor. Synonyms: 2,6,10,14-Tricosatetraene-1,19,23,27-tetrol,3,7,11,15,19,23,27-heptamethyl-30-(tetrahydro-5-(1-hydroxy-1-methylethyl)-2-methyl-2-furanyl)-. CAS No. 144376-63-6. Molecular formula: C45H82O6. Mole weight: 719.13.