BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Indocarbazostatin B | Indocarbazostatin B is originally isolated from Streptomyces sp. TA-0403. In rat pheochromocytoma PC12 cells, the minimum effective concentration of indocarbazostatin B against Neurite outgrowth induced by NGF was 24nmol/L. Molecular formula: C28H22N4O7. Mole weight: 526.50. |  |
| Ingenol-3-mebutate | Ingenol-3-mebutate is a substance found in the sap of the plant Euphorbia peplus and an inducer of cell death. It is effective for field treatment of actinic keratoses, significantly reduced head and non-head actinic keratosis lesions. Synonyms: PEP005; PEP-005; PEP 005; ingenol-3-angelate; Ingenol mebutate. Grade: >98%. CAS No. 75567-37-2. Molecular formula: C25H34O6. Mole weight: 430.53. | |
| Inosamycin A | Inosamycin A is a broad-spectrum antimicrobial antibiotic originally isolated from Str. hygroscopicus No. J296-21. Its antibacterial activity was comparable to that of neomycin, and about twice that of ribomycin. Synonyms: Bu 2659A; 6-Amino-2-{[3-O-(2,6-diamino-2,6-dideoxyhexopyranosyl)pentofuranosyl]oxy}-3,4-dihydroxycyclohexyl 2,6-diamino-2,6-dideoxyhexopyranoside. CAS No. 91421-97-5. Molecular formula: C23H45N5O14. Mole weight: 615.63. | |
| Inosamycin B | Inosamycin B is a broad-spectrum antimicrobial antibiotic originally isolated from Str. hygroscopicus No. J296-21. Its antibacterial activity is about half that of Inosamycin A. Synonyms: Bu 2659B; BMY-28163; 4-O-(2,6-Diamino-2,6-dideoxy-α-D-glucopyranosyl)-5-O-[3-O-(2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl)-β-D-ribofuranosyl]-3-amino-2,3-dideoxy-D-myo-inositol. CAS No. 91465-52-0. Molecular formula: C23H45N5O14. Mole weight: 615.63. | |
| Insignin | Insignin. CAS No. 108598-79-4. Molecular formula: C17H22O4. Mole weight: 290.35. | |
| Irpexan | Irpexan is originally isolated from Irpex sp. 93028. Synonyms: 10-Hydroxy-11-(beta-D-mannopyranosyloxy)-2,6,10,15,19,23-hexamethyl-2,6,14,18,22-tetracosapentaene. Molecular formula: C36H62O7. Mole weight: 606.87. | |
| Isariin B | Isariin B is originally isolated from Isaria felina. Synonyms: 19-hexyl-6-methyl-9-(2-methylpropyl)-3,12-di(propan-2-yl)-1-oxa-4,7,10,13,16-pentaazacyclononadecane-2,5,8,11,14,17-hexone. CAS No. 80111-95-1. Molecular formula: C30H53N5O7. Mole weight: 595.77. | |
| Isariin C | Isariin C is originally isolated from Isaria felina. It has insecticidal effect. Synonyms: 19-hexyl-3,6-dimethyl-9-(2-methylpropyl)-12-(propan-2-yl)-1-oxa-4,7,10,13,16-pentaazacyclononadecane-2,5,8,11,14,17-hexone. CAS No. 80111-96-2. Molecular formula: C28H49N5O7. Mole weight: 567.72. | |
| Isariin D | Isariin D is originally isolated from Isaria felina. It has insecticidal effect. Synonyms: 19-butyl-3,6-dimethyl-9-(2-methylpropyl)-12-(propan-2-yl)-1-oxa-4,7,10,13,16-pentaazacyclononadecane-2,5,8,11,14,17-hexone. Grade: >98%. CAS No. 80111-97-3. Molecular formula: C26H45N5O7. Mole weight: 539.66. | |
| Isoaltenuene | Isoaltenuene is isolated from the solid cultures of the fungus Colletotrichum sp, and it shows antibacterial activity against gram-positive bacteria and exhibits cytotoxic activity against sevral cancer cells. Synonyms: 6H-Dibenzo[b,d]pyran-6-one, 2,3,4,4a-tetrahydro-2,3,7-trihydroxy-9-methoxy-4a-methyl-, (2α,3β,4aα)-; 6H-Dibenzo[b,d]pyran-6-one, 2,3,4,4a-tetrahydro-2,3,7-trihydroxy-9-methoxy-4a-methyl-, (2R,3R,4aS)-rel-; rel-(2R,3R,4aS)-2,3,4,4a-Tetrahydro-2,3,7-trihydroxy-9-methoxy-4a-methyl-6H-dibenzo[b,d]pyran-6-one; (2α,3β,4aα)-(±)-2,3,4,4a-Tetrahydro-2,3,7-trihydroxy-9-methoxy-4a-methyl-6H-dibenzo[b,d]pyran-6-one. Grade: 97.5%. CAS No. 126671-80-5. Molecular formula: C15H16O6. Mole weight: 292.28. | |
| Isoapoptolidin | It is a ring expanded isomer of apoptolidin originally isolated from Nocardiopsis sp. It demonstrates 10-fold reduced F1FO-ATP synthase inhibitory activity compared to apoptolidin (IC50s = 17 and 0.7 μM, respectively). Synonyms: (3E,5E,7E,9R,10R,11E,13E,17S,18S,20S,21R)-10-[(6-Deoxy-4-O-methyl-α-L-glucopyranosyl)oxy]-21-[O-2,6-dideoxy-3-O-methyl-β-D-arabino-hexopyranosyl-(1→4)-O-2,6-dideoxy-3-C-methyl-α-L-arabino-hexopyranosyl-(1→7)-2,4,6-trideoxy-1-C-hydroxy-2,4-dimethyl-8-O-methyl-L-glycero-β-D-galacto-octopyranosyl]-17,20-dihydroxy-18-methoxy-3,5,7,9,13-pentamethyloxacycloheneicosa-3,5,7,11,13-pentaen-2-one; Isoapoptolidin A. Grade: >90% by HPLC. CAS No. 476647-30-0. Molecular formula: C58H96O21. Mole weight: 1129.38. | |
| Isobenzofuranone, 5-methoxy-7-methyl-1(3H)- | Isobenzofuranone, 5-methoxy-7-methyl-1(3H)-. CAS No. 110451-92-8. Molecular formula: C10H10O3. Mole weight: 178.18. | |
| Isochlortetracycline | A metabolite of chlortetracycline, a tetracycline antibiotic. Synonyms: Isoaureomycin; 7-Chloroisotetracycline. Grade: 98%. CAS No. 514-53-4. Molecular formula: C22H23ClN2O8. Mole weight: 478.88. | |
| Isochromophilone III | Isochromophilone III is produced by the strain of Pen. multicolor FO-3216 and FO-2328. It inhibited the ACAT of rat hepatocellular microsome and the B-16 melanoma cell with the IC50 (μmol/L) of 110 and 33. Synonyms: 6H-2-Benzopyran-6-one, 5-chloro-3-(3,5-dimethyl-1,3-heptadienyl)-1,7,8,8a-tetrahydro-7,8-dihydroxy-7-methyl. CAS No. 167173-89-9. Molecular formula: C19H25ClO4. Mole weight: 352.85. | |
| Isochromophilone IV | Isochromophilone IV is produced by the strain of Pen. multicolor FO-3216 and FO-2328. It inhibited the ACAT of rat hepatocellular microsome with the IC50 (μmol/L) of 50. Synonyms: 6H-2-Benzopyran-6-one, 5-(acetyloxy)-5-chloro-3-(3,5-dimethyl-1,3-heptadienyl)-1,7,8,8a-tetrahydro-7-hydroxy-7-methyl; 3-[(1E,3E,5S)-3,5-Dimethyl-1,3-heptadienyl]-5-chloro-7-methyl-7alpha-hydroxy-8alpha-acetoxy-1,7,8,8aalpha-tetrahydro-6H-2-benzopyran-6-one. Grade: >98%. CAS No. 167173-90-2. Molecular formula: C21H27ClO5. Mole weight: 394.89. | |
| Isochromophilone V | Isochromophilone III is produced by the strain of Pen. multicolor FO-3216 and FO-2328. It inhibited the ACAT of rat hepatocellular microsome and the B-16 melanoma cell with the IC50 (μmol/L) of 50 and 36. Synonyms: 6H-2-Benzopyran-6-one, 5-chloro-3-(3,5-dimethyl-1,3-heptadienyl)-7,8-dihydro-7,8-dihydroxy-7-methyl. Grade: >98%. CAS No. 167355-56-8. Molecular formula: C19H23ClO4. Mole weight: 350.84. | |
| Isocycloheximide | It is produced by the strain of Str. griseus. Isocycloheximide has antifungal effect, and its activity to Barbiturates is only 30% of that of actinomyces. Synonyms: D-Isocycloheximide; Caswell No. 504C; (+)-3-(2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)glutarimide; Aktidion. CAS No. 6746-42-5. Molecular formula: C15H23NO4. Mole weight: 281.35. | |
| Isoeverninic acid | Isoeverninic acid. Synonyms: Isoevernic acid. CAS No. 3733-95-7. Molecular formula: C9H10O4. Mole weight: 182.17. | |
| Isohematinic acid | It is produced by the strain of Actinoplanes philippinensis SANK 61681. Isohematinic acid has weak anti-anaerobic bacteria action. Synonyms: (+-)-2,5-Dioxo-4-methylene-3-pyrrolidinepropanoic acid; 3-(5-Hydroxy-4-methylidene-2-oxo-3,4-dihydro-2H-pyrrol-3-yl)propanoic acid. CAS No. 86408-37-9. Molecular formula: C8H9NO4. Mole weight: 183.16. | |
| Isohyperlatolic acid | It is a new depside from the Lichens Dimelaena Oreina and Fuscidea Viridis. Synonyms: Benzoic acid, 2-heptyl-6-hydroxy-4-methoxy-, 4-carboxy-3-hydroxy-5-pentylphenyl ester. CAS No. 90332-19-7. Molecular formula: C27H36O7. Mole weight: 472.57. | |
| Isohyperpicrolichenic acid | Isohyperpicrolichenic acid is a compound obtained from the lichen pertusaria truncata. CAS No. 157241-00-4. Molecular formula: C27H34O7. Mole weight: 470.55. | |
| Isohyperplanaic acid | Isohyperplanaic acid is a compound obtained from the lichen lecanora planaica. CAS No. 156372-08-6. Molecular formula: C29H40O7. Mole weight: 500.62. | |
| Isoleprapinic acid | Isoleprapinic acid. Synonyms: Benzeneacetic acid, α-[3-hydroxy-4-(2-methoxyphenyl)-5-oxo-2(5H)-furanylidene]-, methyl ester, (E)-; Methyl (αE)-α-[3-hydroxy-4-(2-methoxyphenyl)-5-oxo-2(5H)-furanylidene]benzeneacetate. CAS No. 22628-21-3. Molecular formula: C20H16O6. Mole weight: 352.34. | |
| Isoleucyl-aspartic acid | Isoleucyl-aspartic acid is a dipeptide composed of isoleucine and aspartic acid. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: L-Aspartic acid, L-isoleucyl-; L-Isoleucyl-L-aspartic acid; H-ID-OH; Isoleucyl-aspartate; Ile-Asp; (2S)-2-{[(2S,3S)-2-amino-3-methylpentanoyl]amino}succinic acid; L-Aspartic acid, N-L-isoleucyl; (S)-2-((S)-2-Amino-3-methyl-pentanoylamino)-succinic acid. Grade: ≥95%. CAS No. 54532-76-2. Molecular formula: C10H18N2O5. Mole weight: 246.26. | |
| Isoleucyl-lysine | Isoleucyl-lysine is a dipeptide composed of isoleucine and lysine. Synonyms: L-Isoleucyl-L-lysine; Isoleucine Lysine dipeptide. CAS No. 22677-60-7. Molecular formula: C12H25N3O3. Mole weight: 259.35. | |
| Isoleucyl-serine | Isoleucyl-serine is a dipeptide composed of isoleucine and serine. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: H-IS-OH; L-isoleucyl-L-serine; Ile-Ser; L-Ile-L-Ser; L-Serine, L-isoleucyl-; (S)-2-((2S,3S)-2-Amino-3-methylpentanamido)-3-hydroxypropanoic acid; N-L-isoleucyl-L-Serine. Grade: ≥95%. CAS No. 6403-14-1. Molecular formula: C9H18N2O4. Mole weight: 218.25. | |
| Isoleucyl-threonine | Isoleucyl-threonine is a dipeptide composed of isoleucine and threonine. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: H-IT-OH; L-isoleucyl-L-threonine; IT dipeptide; Ile-Thr; L-Threonine, L-isoleucyl-; N-L-isoleucyl-L-Threonine. Grade: ≥95%. CAS No. 59652-61-8. Molecular formula: C10H20N2O4. Mole weight: 232.28. | |
| Isolividic acid | Isolividic acid. | |
| Isolupanine perchlorate | It is an alkaloid that has been found in L. angustifolius. Synonyms: Lupanine perchlorate, (-)-; 7,14-methano-2H,11H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-11-one, dodecahydro-, [7S-[7α,7aα,14α,14aα]-, monoperchlorate; α-Isolupanine perchlorate; 11-Isolupanine monoperchlorate; 7,14-methano-2H,11H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-11-one, dodecahydro-, [7S,7aR,14S,14aR]-, perchlorate (1:1). Grade: ≥95%. CAS No. 14691-01-1. Molecular formula: C15H24N2O.ClHO4. Mole weight: 348.82. | |
| Isomegapicrolichenic acid | Isomegapicrolichenic acid is a compound obtained from the lichen pertusaria truncata. CAS No. 157240-21-6. Molecular formula: C31H42O7. Mole weight: 526.66. | |
| Isomerochlorophaeic acid | Isomerochlorophaeic acid. | |
| Isomuronic acid | It is isolated from the lichen Punctelia microsticta. Synonyms: 3-Furancarboxylic acid, 2,5-dihydro-4-methyl-5-oxo-2-(14-oxopentadecyl)-, (2R)-; (R)-4-Methyl-5-oxo-2-(14-oxo-pentadecyl)-2,5-dihydro-furan-3-carboxylic acid; (2R)-4-methyl-5-oxo-2-(14-oxopentadecyl)-2H-furan-3-carboxylic acid. CAS No. 70579-66-7. Molecular formula: C21H34O5. Mole weight: 366.49. | |
| Isonanangenine B | Isonanangenine B is a drimane sesquiterpene lactone isolated from Aspergillus nanangensis. Ionanpurine B is moderately active against Bacillus subtilis (IC50 56μg/mL), but it is more cytotoxic to a variety of tumor cell lines. Grade: >95% by HPLC. CAS No. 1623153-14-9. Molecular formula: C21H32O6. Mole weight: 380.5. | |
| Isonorlobaridone | Isonorlobaridone. CAS No. 155214-63-4. | |
| Isonorobtusatic acid | Isobornyl acid can inhibit the growth of mouse SV40-transformed breast cancer cells in vitro. CAS No. 132396-90-8. Molecular formula: C17H16O7. Mole weight: 332.3. | |
| Isonotatic acid | It has been detected in strains of the lichen Parmelia notata Kurok. Synonyms: 11H-dibenzo[b,e][1,4]dioxepine-7-carboxylic acid, 8-hydroxy-3-methoxy-1,6,9-trimethyl-11-oxo-. CAS No. 90689-48-8. Molecular formula: C18H16O7. Mole weight: 344.32. | |
| Isoobtusatic acid | Isoobtusatic acid. Synonyms: Benzoic acid, 2-hydroxy-4-[(2-hydroxy-4-methoxy-6-methylbenzoyl)oxy]-3,6-dimethyl-; 3'-methyl evernic acid. CAS No. 70342-22-2. Molecular formula: C18H18O7. Mole weight: 346.33. | |
| Isopatagonic acid | Isopatagonic acid is a dibenzofuran compound obtained from lichen bunodophoron patagonicum. CAS No. 158202-34-7. Molecular formula: C25H30O8. Mole weight: 458.5. | |
| Isophysodic acid | Isophysodic acid is a lichenic acid isolated from Hypogymnia physodes. Synonyms: 4,6-Dihydroxy-3-[(6-hydroxy-1-oxo-3-pentyl-1H-2-benzopyran-8-yl)oxy]-2-pentylbenzoic acid; Benzoic acid, 4,6-dihydroxy-3-[(6-hydroxy-1-oxo-3-pentyl-1H-2-benzopyran-8-yl)oxy]-2-pentyl-. CAS No. 188347-29-7. Molecular formula: C26H30O8. Mole weight: 470.51. | |
| (-)-isopimara-9(11),15-diene-3β,19-diol | (-)-isopimara-9(11),15-diene-3β,19-diol. Synonyms: 1-Phenanthrenemethanol, 7-ethenyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-2-hydroxy-1,4a,7-trimethyl-, [1S-(1α,2α,4aα,7β,8aα,10aβ)]-; (-)-Isopimara-9(11),15-diene-3β,19-diol; Isopimara-9(11),15-diene-3β,19-diol. CAS No. 39702-18-6. Molecular formula: C20H32O2. Mole weight: 304.47. | |
| Isoquinocycline A | Isoquinocycline A is originally isolated from Str. aureofaciens. It has strong anti-mycobacterium activity. Molecular formula: C33H34N2O10. Mole weight: 618.63. | |
| Isoreserpiline | Isoreserpiline is an indole alkaloid isolated from Rhodiola crassifolia and has a variety of biological activities. Isoergophylline has antihypertensive and antipsychotic activities. Synonyms: 3-Isoreserpiline. Grade: >95% by HPLC. CAS No. 572-67-8. Molecular formula: C23H28N2O5. Mole weight: 412.48. | |
| Isorhizonic acid | Isorhizonic acid. Synonyms: Benzoic acid, 4-hydroxy-2-methoxy-3,6-dimethyl-; 4-Oxy-6-methoxy-2,5-dimethyl-benzoesaeure; Isorhizoinsaeure. CAS No. 6709-55-3. Molecular formula: C10H12O4. Mole weight: 196.20. | |
| Isosativenediol | Isosativenediol is produced from the culture filtrates of a Bipolaris species pathogenic to Johnson grass. Synonyms: 2,4-Methano-1H-indene-3,8-diol, octahydro-7a-methyl-1-methylene-5-(1-methylethyl)-, (2R,3R,3aR,4R,5S,7aS,8R)-rel-(-)-; 2,4-Methano-1H-indene-1,3-diol, octahydro-4-methyl-8-methylene-7-(1-methylethyl)-, (1α,2α,3β,3aβ,4α,7α,7aβ)-(-)-. Grade: 98.5%. CAS No. 57079-92-2. Molecular formula: C15H24O2. Mole weight: 236.35. | |
| Isoschizopeltic acid | Isoschizopeltic acid. | |
| Isosphaeric acid | It is a new depside and an isomer of sphaerophorin from the Lichens Dimelaena Oreina and Fuscidea Viridis. Synonyms: Benzoic acid, 2-heptyl-6-hydroxy-4-methoxy-, 4-carboxy-3-hydroxy-5-methylphenyl ester. CAS No. 90332-22-2. Molecular formula: C23H28O7. Mole weight: 416.46. | |
| Isosulfazecin | Isosulfazecin is a beta-lactam antibiotic produced by the strain of Pseudomonas mesoacidophila sp. nov. Its anti-gram-positive bacteria effect is similar to SZ (Sulfazecin), but its anti-gram-negative bacteria activity is weaker than SZ. Synonyms: (R)-D-gamma-Glutamyl-N-(3-methoxy-2-oxo-1-sulfo-3-azetidinyl)-L-alaninamide; (3R)-2-Oxo-3-methoxy-3beta-[[N-[(4R)-4-amino-4-carboxybutyryl]alanyl]amino]azetidine-1-sulfonic acid. Grade: >98%. CAS No. 77900-75-5. Molecular formula: C12H20N4O9S. Mole weight: 396.38. | |
| Isovicanicin | It has been isolated from Psoroma lichens. Synonyms: 11H-Dibenzo[b,e][1,4]dioxepin-11-one, 2,7-dichloro-8-hydroxy-3-methoxy-1,4,6,9-tetramethyl-. CAS No. 84592-15-4. Molecular formula: C18H16Cl2O5. Mole weight: 383.22. | |
| (±)-Isoxanthohumol | It is one of many bioactive prenylflavonoids that can be isolated from the hops plant or humulus lupulus L. It has apparent chemotherapeutic prevention activity. It has also shown notable antiviral, antibacterial and antifungal activity. Synonyms: 2,3-Dihydro-7-hydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one; 4',7-Dihydroxy-5-methoxy-8-(3-methyl-2-butenyl)-flavanone; 5-Methylsophoraflavanone B; 4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methyl-2-buten-1-yl)-; 4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methyl-2-butenyl)-; Flavanone, 4',7-dihydroxy-5-methoxy-8-(3-methyl-2-butenyl)-; Isoxanthohumol. Grade: 96%. CAS No. 521-48-2. Molecular formula: C21H22O5. Mole weight: 354.40. | |
| Istamycin A | Istamycin A is produced by the strain of Str. tenjimariensis S5-939. It has strong anti-gram positive and negative bacteria action, and Istamycin B has stronger antibacterial activity than A. Synonyms: Sannamycin A; Antibiotic KA 7038I; L-chiro-Inositol, 4-amino-1-((aminoacetyl)methylamino)-3-O-(2-amino-2,3,4,6-tetradeoxy-6-(methylamino)-alpha-D-erythro-hexopyranosyl)-1,4,5-trideoxy-6-O-methyl-. CAS No. 72503-79-8. Molecular formula: C17H35N5O5. Mole weight: 389.49. | |
| Istamycin B | Istamycin B is produced by the strain of Str. tenjimariensis S5-939. It has strong anti-gram positive and negative bacteria action, and Istamycin B has stronger antibacterial activity than A. Synonyms: L-chiro-Inositol, 4-amino-1-(2-amino-N-methylacetamido)-3-O-(2-amino-6-methylamino-2,3,4,6-tetradeoxy-beta-D-lyxo-hexopyranosyl)-6-O-methyl-1,4,5-trideoxy-. CAS No. 72523-64-9. Molecular formula: C17H35N5O5. Mole weight: 389.49. | |
| IT-143-A | IT-143-A is produced by the strain of Streptomyces sp.IT-143. It has activity against individual gram-positive bacteria (Micrococcus gaminerae) and individual fungi (Aspergillus fumigatus). And it is also cytotoxic to KB cells. Synonyms: IT-143A. Molecular formula: C29H43NO4. Mole weight: 469.65. | |
| IT-62-B | IT-62-B is originally isolated from Streptomyces sp. IT-62. It had moderate anti-Gram-positive bacteria activity (MIC 6.25-12.5 μg/mL), and anti-L1210, P388, adriamycin-resistant P388 and KB tumor cells activity. Molecular formula: C39H47NO15. Mole weight: 769.79. | |
| Izumenolide | It is produced by the strain of Micromonospora chalcea subsp. izumensis. Izumenolide inhibited some β-lactamases, and the IC50 concentration of TEM-2 β-lactamase was 0.01 μg/mL. Synonyms: EM-4615-A; Oxacyclotriacont-3-en-2-one, 16,18-bis(sulfooxy)-30-(2-(sulfooxy)-9-undecenyl)-. CAS No. 76265-39-9. Molecular formula: C40H74O14S3. Mole weight: 875.20. | |
| Jadomycin B | Jadomycin B is an angucyclic natural product produced by Streptomyces venezuelae ISP5230. It exhibits antimicrobial, antitumor activity and inhibits aurora-B kinase and DNA cleaving. It was also shown to be effective against a variety of staphylococci. Synonyms: 1-(sec-butyl)-12-((4,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-7-hydroxy-5-methyl-8H-benzo[b]oxazolo[3,2-f]phenanthridine-2,8,13(1H,3aH)-trione; 8H-Benzo(b)oxazolo(3,2-f)phenanthridine-2,8,13(1H,3aH)-trione, 12-((2,6-dideoxyhexopyranosyl)oxy)-7-hydroxy-5-methyl-1-(1-methylpropyl)-. Grade: ≥98% by HPLC. CAS No. 149633-99-8. Molecular formula: C30H31NO9. Mole weight: 549.6. | |
| Janthinocin A | It is produced by the strain of Janthinobacterium lividum. Janthinocin A has strong activity of anti-gram-positive bacteria and moderate anti-gram-negative bacteria, and has strong inhibitory effect on drug-resistant staphylococcus such as penicillin, tetracycline, erythromycin, methicillin and gentamicin. CAS No. 131086-52-7. Molecular formula: C57H84N12O16. Mole weight: 1193.34. | |
| Janthinocin B | It is produced by the strain of Janthinobacterium lividum. Janthinocin B has strong activity of anti-gram-positive bacteria and moderate anti-gram-negative bacteria, and has strong inhibitory effect on drug-resistant staphylococcus such as penicillin, tetracycline, erythromycin, methicillin and gentamicin. Synonyms: 8-(alpha,beta-Didehydro-beta-hydroxytryptophan)janthinocin A; Janthinocin A, 8-(alpha,beta-didehydro-beta-hydroxytryptophan)-. CAS No. 131086-53-8. Molecular formula: C57H82N12O16. Mole weight: 1191.33. | |
| Janthitrem B | It is a tremorgenic mycotoxin produced by the strain of Penicillium Janthinellum. Synonyms: 34-deoxy-34,35-didehydro-janthitrem E; (2R,3R,4bS,6aS,9S,9aR,15bS,15cR,17aS)-10,10,12,12,15b,15c-hexamethyl-2-(prop-1-en-2-yl)-2,3,5,6,6a,7,9,9a,10,12,15,15b,15c,16,17,17a-hexadecahydro-4bH-chromeno[5',6':6,7]indeno[1,2-b]pyrano[4',3':3,4]cyclopenta[1,2-f]indole-3,4b,9-triol; 4bH-Pyrano[2'',3'':5',6']benz[1',2':6,7]indeno[1,2-b]pyrano[4',3':3,4]cyclopent[1,2-f]indole-3,4b,9-triol,2,3,5,6,6a,7,9,9a,10,12,15,15b,15c,16,17,17a-hexadecahydro-10,10,12,12,15b,15c-hexamethyl-2-(1-methylethenyl)-, (2R,3R,4bS,6aS,9S,9aR,15bS,15cR,17aS)-. CAS No. 73561-90-7. Molecular formula: C37H47NO5. Mole weight: 585.77. | |
| Jawsamycin | It is produced by the strain of Streptoverticillium fervens. Jawsamycin had strong anti-filamentous fungal activity, and the MIC of Aspergillus Niger, Aureobasidium and Mucor was 0.05 μg/mL. Synonyms: FR-900848; FR900848. CAS No. 120500-69-8. Molecular formula: C32H43N3O6. Mole weight: 565.70. | |
| Jenamidine A | It inhibited K-562 proliferation of chronic myeloid leukemia cells with Gl50 of 1.9 μg/mL. Molecular formula: C13H18N2O3. Mole weight: 250.29. | |
| Jietacin A | Jietacin A is originally isolated from Str. sp. KP-197. It is found to be resistant to nematode, it can 100% kill Burs helenchus Lignicolus with the concentration of 0.25μg/mL, which is 10 times stronger than Avermectin B1a. Synonyms: Jietacine A; BRN 5538455; 1-(Ethenyl-ONN-azoxy)-14-methyl-8-pentadecanone. CAS No. 109766-61-2. Molecular formula: C18H34N2O2. Mole weight: 310.47. | |
| Jietacin B | Jietacin B is originally isolated from Str. sp. KP-197. It is found to be resistant to nematode, it can 100% kill Burs helenchus Lignicolus with the concentration of 0.25μg/mL, which is 10 times stronger than Avermectin B1a. CAS No. 109766-62-3. Molecular formula: C19H36N2O2. Mole weight: 324.50. | |
| Juglomycin A | Juglomycin A is originally isolated from Str. distatochromogenes var. juglonensis 190-2. It has a broad spectrum of antibacterial and mycobacterial effects, and has the effect of inhibiting ehrlician ascites cancer in mice and prolongating life with 1 mg/kg. Synonyms: (-)-Juglomycin A; 1,4-Naphthalenedione,5-hydroxy-2-[(2R,3R)-tetrahydro-3-hydroxy-5-oxo-2-furanyl]-. CAS No. 38637-88-6. Molecular formula: C14H10O6. Mole weight: 274.22. | |
| Juglomycin B | Juglomycin B is originally isolated from Str. distatochromogenes var. juglonensis 190-2. It has a broad spectrum of antibacterial and mycobacterial effects, and has the effect of inhibiting ehrlician ascites cancer in mice and prolongating life with 1 mg/kg. Synonyms: (+/-)-juglomycin A. CAS No. 38637-89-7. Molecular formula: C14H10O6. Mole weight: 274.22. | |
| Juvenimicin A2 | It is produced by the strain of Micromono spora chalcea var. izumensis. Juvenimicin A2 can resist gram-positive bacteria and individual gram-negative bacteria. Synonyms: BRN 1413776; 6-De(2-oxoethyl)-4'-deoxy-6-methylcirramycin A1. CAS No. 61417-47-8. Molecular formula: C30H51NO8. Mole weight: 553.73. | |
| K-1115A | It is produced by the strain of Streptomyces griseorubiginosus Mer-K1115. K1115A inhibited the direct binding of activator protein-1 (AP-1) to AP-1 oligonucleotide (IC50 = 100 microM), and the production of collagenase in IL-1 alpha-stimulated rat synovial cells (IC50 = 60 microM). Synonyms: K1115 A; 2-Anthracenecarboxylic acid, 9,10-dihydro-3,8-dihydroxy-9,10-dioxo-1-propyl-. CAS No. 208525-17-1. Molecular formula: C18H14O6. Mole weight: 326.30. | |
| K1115 B1 | It is a co-produced compound of K-1115A produced by the strain of Streptomyces griseorubiginosus Mer-K1115. K1115 B1 inhibited the direct binding of activator protein-1 (AP-1) to AP-1 oligonucleotide, and the production of collagenase in IL-1 alpha-stimulated rat synovial cells. Synonyms: XR-573. Molecular formula: C22H24O8. Mole weight: 416.42. | |
| K1115 B2 | It is a co-produced compound of K-1115A produced by the strain of Streptomyces griseorubiginosus Mer-K1115. K1115 B2 inhibited the direct binding of activator protein-1 (AP-1) to AP-1 oligonucleotide, and the production of collagenase in IL-1 alpha-stimulated rat synovial cells. Molecular formula: C23H26O9. Mole weight: 446.45. | |
| K-13 | K-13 is a noncompetitive inhibitor of angiotensin I converting enzyme from Micromonospora halophytica subsp. exilisia K-13. Synonyms: L-Tyrosine, N-acetyl-L-tyrosyl-L-tyrosyl-3-hydroxy-, cyclic (1-3(sup 3))-ether. CAS No. 108890-90-0. Molecular formula: C29H29N3O8. Mole weight: 547.55. | |
| K-252b | A staurosporine analogue isolated from a nocardiopsis strain; a potent inhibitor of protein kinase C. K-252b exhibits potent antitumour activity but shows no antimicrobial activity in vitro, or in vivo toxicity in rodents; also active against other kinases, notably myosin light chain kinase, camp-dependent protein kinase (PKA), protein kinase C (PKC) and cgmp-dependent protein kinase (PKG). Synonyms: (9r,10s,12s)-2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1h-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid. Grade: >98% by HPLC. CAS No. 99570-78-2. Molecular formula: C26H19N3O5. Mole weight: 453.45. | |
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