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Lachnone A
It is a chromone isolated from the filamentous fungus, lachnum sp. It possesses weak activity against bacteria but has not been extensively investigated. Synonyms: Lanchnone A; 3,?5-Dihydroxy-2,?7-dimethyl-4H-1-benzopyran-4-one. Grade: >95% by HPLC. CAS No. 903892-99-9. Molecular formula: C11H10O4. Mole weight: 206.19.
Lachnumol A
It is produced by the strain of Lachnum papyraceum. It has weaker activity against bacteria, yeast and filamentous fungi. It has cytotoxic activity against L1210, HeLa, KB and other cell lines. Synonyms: La; 1-chloro-6-[(Z)-1-chloroprop-1-enyl]-4-methoxy-7-oxabicyclo[4.1.0]hept-3-ene-2,5-diol; 7-Oxabicyclo(4.1.0)hept-3-ene-2,5-diol, 6-chloro-1-(1-chloro-1-propenyl)-3-methoxy-. CAS No. 150671-03-7. Molecular formula: C10H12Cl2O4. Mole weight: 267.11.
Lachnumon
It is produced by the strain of Lachnum papyraceum. It has weaker activity against bacteria, yeast and filamentous fungi. It has cytotoxic activity against L1210, HeLa, KB and other cell lines. Synonyms: Ln; 7-Oxabicyclo(4.1.0)hept-3-en-2-one, 1-chloro-6-(1-chloro-1-propenyl)-5-hydroxy-4-methoxy-; 6-chloro-1-[(Z)-1-chloroprop-1-enyl]-2-hydroxy-3-methoxy-7-oxabicyclo[4.1.0]hept-3-en-5-one. CAS No. 150671-02-6. Molecular formula: C10H10Cl2O4. Mole weight: 265.09.
Lactaroviolin
It is produced by the strain of Lactarius deliciosus. It is an aromatic derivative antibiotic. It can inhibit the growth of Mycobacterium tuberculosis, but the effect is not strong. Synonyms: Lactarioviolin; 1-Azulenecarboxaldehyde, 4-methyl-7-(1-methylethenyl)-; 1-Formyl-7-isopropenyl-4-methylazulene; 1,3,5,7,9,11-Guaiahexaen-15-al; 7-Isopropenyl-4-methyl-1-Azulenecarboxaldehyde. CAS No. 85-33-6. Molecular formula: C15H14O. Mole weight: 210.27.
Lactonamycin Z
It is produced by the strain of Streptomyces sp. AK 623. It's an antitumor antibiotic. It has weak anti-gram-positive bacterial activity. It can inhibit human tumor cells HMO2, MCF7 and Hep G2 with GI50 (μg/mL) of 1.9, 0.85 and 5.11, respectively. Molecular formula: C28H27NO13. Mole weight: 585.51.
Lactoquinomycin B
It is produced by the strain of Str. tanashiensis IM 8442T. It's a quinone antibiotic. It has the activity of anti-gram-positive bacteria and some gram-negative bacteria, but the effect of anti-gram-negative bacteria is weak and has no effect on fungi. Lactoquinomycin A has stronger antibacterial activity than Lactoquinomycin B. It inhibits a variety of cell lines including lymphoma L5178Y progenitor, adriamycin resistant, bleomycin-resistant, human leukemia K562, mouse leukemia L-1210 and mouse leukemia P 388 with ID50 (μg/mL) of 0.43, 0.21, 0.19, 0.16, 0.2 and 0.12, respectively. Synonyms: 3a,11b-Dihydro-7-hydroxy-5-methyl-8-[2,3,6-trideoxy-3-(dimethylamino)-β-D-arabino-hexopyranosyl]-5a,11a-epoxy-5H-furo[3,2-b]naphtho[2,3-d]pyran-2,6,11(3H)-trione; 5a,11a-Epoxy-5H-furo[3,2-b]naphtho[2,3-d]pyran-2,6,11(3H)-trione, 3a,11b-dihydro-7-hydroxy-5-methyl-8-[2,3,6-trideoxy-3-(dimethylamino)-b-D-arabino-hexopyranosyl]-. CAS No. 101342-94-3. Molecular formula: C24H27NO9. Mole weight: 473.48.
Lactosillan
It is produced by the strain of Alcaligenes latus G66A. Latosillan is a cell differentiation inducer that can differentiate myeloid leukemia cells into macrophages. Synonyms: Latosillan. CAS No. 83712-86-1. Molecular formula: C32H55NO23. Mole weight: 821.77.
Lagunamycin
It is produced by the strain of Str. sp. AA0310. It can inhibit 5-fat oxygenase with IC50 of 6.08 μmol/L, but dose not inhibit lipid peroxidation. It has the activity of anti-gram-positive bacteria, not anti-gram-negative bacteria. Synonyms: (E)-(-)-6-Diazo-3-methyl-4-(1,3,5-trimethyl-1-hexenyl)-2,5,7,8(1H,6H)-quinolinetetrone; 6-diazonio-4-[(E)-4,6-dimethylhept-2-en-2-yl]-3-methyl-2,7,8-trioxo-1H-quinolin-5-olate. Grade: 95%. CAS No. 150693-65-5. Molecular formula: C19H21N3O4. Mole weight: 355.39.
It is produced by the strain of Lambertella hicoriae, Lam. cornimaris. It's a quinone antibiotic. It has anti-gram-positive bacterial and fungal activity. Synonyms: 2H-Naphtho(2,3-b)pyran-2,5,10-trione, 9-hydroxy-3-methyl-; 9-hydroxy-3-methyl-2h-naphtho-(2,3-b)pyran-2,5,10-trione. CAS No. 28980-51-0. Molecular formula: C14H8O5. Mole weight: 256.21.
Lankamycin
It is produced by the strain of Str. violaceoniger NRRL 2834. It's a macrolide antibiotic. It has weak anti-gram-positive bacterial activity. It has cross-resistance with Picromycin and synergistic effect with Lankacidin. Synonyms: Lankavamycin; Kujimycin B; Antibiotic A-20338-N2; [3R-[3R*,4S*,5R*,6S*,7S*,9S*,11R*,12S*,13S*,14R*(1S*,2S*)]]-4-[(4-O-Acetyl-2,6-dideoxy-3-C-methyl-3-O-methyl-a-L-xylo-hexopyranosyl)oxy]-12-(acetyloxy)-6-[(4,6-dideoxy-3-O-methyl-b-D-xylo-hexopyranosyl)oxy]-9-hydroxy-14-(2-hydroxy-1-methylpropyl)-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione. Grade: 98%. CAS No. 30042-37-6. Molecular formula: C42H72O16. Mole weight: 833.02.
Lanopylin A1
It is produced by the strain of Streptomyces sp. K99-5041. It can inhibit recombinant human lanosterol synthase (EC 5.4.99.7) with IC50 of 15 μmol/L. Synonyms: 2-Methyl-3-[(E)-15-methylhexadecane-1-ylidene]-4,5-dihydro-3H-pyrrole. Molecular formula: C22H41N. Mole weight: 319.57.
Lanopylin A2
It is produced by the strain of Streptomyces sp. K99-5041. It can inhibit recombinant human lanosterol synthase (EC 5.4.99.7) with IC50 of 18 μmol/L. Molecular formula: C24H43N. Mole weight: 345.60.
Lanopylin B1
It is produced by the strain of Streptomyces sp. K99-5041. It can inhibit recombinant human lanosterol synthase (EC 5.4.99.7) with IC50 of 33 μmol/L. Synonyms: 2-Methyl-3-[(E)-heptadecane-1-ylidene]-4,5-dihydro-3H-pyrrole. Molecular formula: C22H41N. Mole weight: 319.57.
Lanopylin B2
It is produced by the strain of Streptomyces sp. K99-5041. It can inhibit recombinant human lanosterol synthase (EC 5.4.99.7) with IC50 of 41 μmol/L. Molecular formula: C24H43N. Mole weight: 345.60.
Lasallic acid is a tridepside from the lichen Lasallia asiae-orientalis. Synonyms: 3-Carboxy-2,6-dihydroxy-4-methylphenyl 4-[(2,4-dihydroxy-6-methylbenzoyl)oxy]-2-hydroxy-6-methylbenzoate; Benzoic acid, 4-[(2,4-dihydroxy-6-methylbenzoyl)oxy]-2-hydroxy-6-methyl-, 3-carboxy-2,6-dihydroxy-4-methylphenyl ester. CAS No. 177795-28-7. Molecular formula: C24H20O11. Mole weight: 484.41.
Lasalocid B
It is produced by the strain of Str. lasaliensis. It has anti-gram-positive bacteria and protozoa activity. It is added to feed to prevent coccidiosis in chickens. Synonyms: 3-Ethyl-6-[(3R,4S,5S,7R)-7-[(2S,3S,5S)-5-ethyl-5-[(2R,5R)-tetrahydro-5-ethyl-5-hydroxy-6α-methyl-2H-pyran-2-yl]tetrahydro-3-methylfuran-2-yl]-4-hydroxy-3,5-dimethyl-6-oxononyl]-2-hydroxybenzoic acid. CAS No. 55051-86-0. Molecular formula: C35H56O8. Mole weight: 604.81.
Lasalocid C
It is produced by the strain of Str. lasaliensis. It has anti-gram-positive bacteria and protozoa activity. It is added to feed to prevent coccidiosis in chickens. Synonyms: Benzoic acid, 6-[3-ethyl-7-[5-ethyl-5-(5-ethyltetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)tetrahydro-3-methyl-2-furanyl]-4-hydroxy-5-methyl-6-oxononyl]-2-hydroxy-3-methyl-, [2R-[2a[2S*(3R*,4S*,5S*,7R*),3S*,5S*],5a,6b]]-. CAS No. 55051-84-8. Molecular formula: C35H56O8. Mole weight: 604.81.
Lasalocid E
It is produced by the strain of Str. lasaliensis. It has anti-gram-positive bacteria and protozoa activity. It is added to feed to prevent coccidiosis in chickens. Synonyms: Benzoic acid, 6-[(3R,4S,5S,7R)-5-ethyl-7-[(2S,3S,5S)-5-ethyl-5-[(2R,5R,6S)-5-ethyltetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl]-tetrahydro-3-methyl-2-furanyl]-4-hydroxy-3-methyl-6-oxononyl]-2-hydroxy-3-methyl-. CAS No. 55051-82-6. Molecular formula: C35H56O8. Mole weight: 604.81.
L-asparaginyl-L-aspartic acid is a dipeptide composed of asparagine and aspartic acid. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: H-ND-OH; L-asparagyl-L-aspartic acid; Asparaginyl-aspartate; Asn-Asp; L-Asn-L-Asp; L-Aspartic acid, L-asparaginyl-; (S)-2-((S)-2,4-Diamino-4-oxobutanamido)succinic acid. Grade: ≥95%. CAS No. 61365-15-9. Molecular formula: C8H13N3O6. Mole weight: 247.21.
L-asparaginyl-L-threonine
L-asparaginyl-L-threonine is a dipeptide composed of asparagine and threonine. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: Asparaginyl-threonine; H-NT-OH; L-Threonine, L-asparaginyl-; N-L-Asparaginyl-L-threonine; Asn-Thr; L-Asn-L-Thr-OH; (S)-2-((S)-2-Amino-3-carbamoyl-propionylamino)-3-hydroxy-butyric acid. Grade: ≥98%. CAS No. 40043-76-3. Molecular formula: C8H15N3O5. Mole weight: 233.22.
L-Aspartyl-L-Proline
L-Aspartyl-L-Proline is a dipeptide composed of aspartic acid and proline. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: Aspartyl-L-proline; Aspartyl-proline; L-α-Aspartyl-L-proline; Aspartylproline; Asp-pro; 1-L-alpha-aspartyl-L-Proline; (S)-1-((S)-2-Amino-3-carboxypropanoyl)pyrrolidine-2-carboxylic acid; L-alpha-Aspartyl-L-proline. Grade: ≥98%. CAS No. 42155-95-3. Molecular formula: C9H14N2O5. Mole weight: 230.22.
Lateropyrone
An unusual heterocyclic metabolite isolated from fusarium avenaceum with antibacterial and antifungal activity. Synonyms: Avenacein Y. Grade: >99% by HPLC. CAS No. 93752-78-4. Molecular formula: C15H10O8. Mole weight: 318.23.
Lavanducyanin
Lavanducyanin is a testosterone 5 alpha-reductase inhibitor isolated from Streptomyces sp. No. 9659. It exhibits weak activity against gram-positive bacteria. Synonyms: WS-9659 A; WS-9659A; WS 9659 A. CAS No. 122228-60-8. Molecular formula: C22H24N2O. Mole weight: 332.4.
Lavanduquinocin
It is produced by the strain of Str. viridochromogen. It is a protective agent of nerve cells and has the effect of reducing L-glutamate on cytotoxicity of neuronal hybridoma N18-RE-105 with ED50 of 15.5 nmol/L. Synonyms: (R)-1-(2-hydroxypropyl)-2-methyl-6-((2,4,4-trimethylcyclohex-1-en-1-yl)methyl)-3H-carbazole-3,4(9H)-dione; 3H-Carbazole-3,4(9H)-dione, 1-(2-hydroxypropyl)-2-methyl-6-[(2,4,4-trimethyl-1-cyclohexen-1-yl)methyl]-, (R)-; Lavanduquinocine. CAS No. 167114-85-4. Molecular formula: C26H31NO3. Mole weight: 405.53.
Lavendamycin
It is produced by the strain of Str. lavendulae C-22030. It's a quinone antibiotic. It has anti-bacterial and fungal effect, but the anti-bacterial effect is weaker than Streptonigrin, while the anti-fungal effect is stronger than Streptonigrin. Synonyms: 9H-Pyrido(3,4-b)indole-3-carboxylic acid, 1-(7-amino-5,8-dihydro-5,8-dioxo-2-quinolinyl)-4-methyl-; Antibiotic K 82A. CAS No. 81645-09-2. Molecular formula: C22H14N4O4. Mole weight: 398.38.
Lavendomycin
It is produced by the strain of Str. lavendulae subsp. brasillicus. It has strong activity against Staphylococcus aureus, Staphylococcus epidermococcus and Streptococcus faecalis with ED50 (mg/kg) of 2.33, 1.68 and 13.2, respectively (In vivo test in mice, abdominal infection, subcutaneous administration). It has no anti-gram-negative bacteria and fungi activity. Synonyms: Antibiotic FR 900201; ((Z)-2-((S)-1-((S)-1-((2S,3R)-3-amino-2-((2S,3R)-2-amino-5-guanidino-3-methylpentanamido)butanoyl)piperidine-2-carbonyl)pyrrolidine-2-carboxamido)but-2-enoyl)-L-serine. Grade: ≥95%. CAS No. 82987-09-5. Molecular formula: C29H50N10O8. Mole weight: 666.78.
L-Cysteinamide
L-Cysteinamide. CAS No. 74401-72-2. Molecular formula: C3H8N2OS. Mole weight: 120.2.
L-Cysteinol
L-Cysteinol. CAS No. 125509-78-6. Molecular formula: C3H9NOS. Mole weight: 107.2.
Lecideoidin
It is the depsidone isolated from a Lecidea sp. Synonyms: 11H-Dibenzo[b,e][1,4]dioxepin-7-carboxylic acid, 2,9-dichloro-3,8-dihydroxy-1,6-dimethyl-11-oxo-, methyl ester; 2,9-Dichloro-3,8-dihydroxy-1,6-dimethyl-11-oxo-11H-dibenzo[b,e][1,4]dioxepine-7-carboxylic acid methyl ester. CAS No. 72458-10-7. Molecular formula: C17H12Cl2O7. Mole weight: 399.18.
Lenoremycin
It is a polyether antibiotic produced by the strain of Streptomyces hygroscopicus A-130. It has the effect of anti-gram-positive bacteria, mycobacterium and protozoa, and can be used as a feed additive to control Eimeriatenella infection. Synonyms: Antibiotic A-130A; A-130A; Antibiotic Ro 21 6150; Dianemycin, 10-demethyl-19-de[(tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl)oxy]-12-methyl-11-O-(tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl)-, [11(2R,5S,6R),12R]-; 6-Nonenoic acid, 8-[2,4',10,10'-tetramethyl-2'-[tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-9-[(tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl)oxy][2,7'-bi-1,6-dioxaspiro[4.5]dec]-7-yl]-2,4,6-trimethyl-5-oxo-, [2S-[2a[2'S*,4'R*,5'S*,7'S*[2R*,5S*,7R*(2R*,4S*,6E,8R*),9S*(2S*,5R*,6S*),10S*],10'S*],3b,5b,6b]]-. CAS No. 51257-84-2. Molecular formula: C47H78O13. Mole weight: 851.11.
Lenoremycin sodium
It is a polyether antibiotic produced by the strain of Streptomyces hygroscopicus A-130. It has the effect of anti-gram-positive bacteria, mycobacterium and protozoa, and can be used as a feed additive to control Eimeriatenella infection. Synonyms: Antibiotic A130 sodium salt; Dianemycin, 10-demethyl-19-de((tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl)oxy)-12-methyl-11-O-(tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl)-, monosodium salt, (11(2R,5S,6R),12R)-; Antibiotic A-130A Sodium salt. CAS No. 58399-44-3. Molecular formula: C47H77NaO13. Mole weight: 873.10.
Leprapinic acid
Leprapinic acid is a member of methoxybenzenes. Synonyms: Leprapic acid; methyl (E)-2-(3-hydroxy-5-oxo-4-phenylfuran-2(5H)-ylidene)-2-(2-methoxyphenyl)acetate; Benzeneacetic acid, alpha-(3-hydroxy-5-oxo-4-phenyl-2(5H)-furanylidene)-2-methoxy-, methyl ester, (E)-; α-[(2E)-3-Hydroxy-5-oxo-4-phenyl-2,5-dihydrofuran-2-ylidene]-2-methoxybenzeneacetic acid methyl ester; Benzeneacetic acid, α-(3-hydroxy-5-oxo-4-phenyl-2(5H)-furanylidene)-2-methoxy-, methyl ester, (αE)-; [3-Hydroxy-5-oxo-4-phenyl-5H-furan-(2E)-ylidene]-(2-methoxy-phenyl)-acetic acid methyl ester. CAS No. 481-59-4. Molecular formula: C20H16O6. Mole weight: 352.34.
2,7-Dichloronorlichexanthone is a lichen chromone found in ascomycete licheniformis. Synonyms: Glutaconic acid, 3-methyl-, 1-[(5-hydroxy-7-methoxy-2-methyl-4-oxo-4H-1-benzopyran-6-yl)methyl] ester (8CI); 1-[(5-Hydroxy-7-methoxy-2-methyl-4-oxo-4H-1-benzopyran-6-yl)methyl] 3-methyl-2-pentenedioate; Fuciformic acid; 2-Pentenedioic acid, 3-methyl-, 1-[(5-hydroxy-7-methoxy-2-methyl-4-oxo-4H-1-benzopyran-6-yl)methyl] ester. CAS No. 22399-41-3. Molecular formula: C18H18O8. Mole weight: 362.33.
Leprolomin
It is a novel diphenyl ether isolated from the lichen psoroma leprolomum. Synonyms: Ethanone, 1-[6-(3-acetyl-2,6-dihydroxy-4-methoxy-5-methylphenoxy)-2-hydroxy-4-methoxy-3-methylphenyl]-; 1-(6-(3-acetyl-2,6-dihydroxy-4-methoxy-5-methylphenoxy)-2-hydroxy-4-methoxy-3-methylphenyl)ethan-1-one; NSC 646011. Grade: ≥98%. CAS No. 68984-67-8. Molecular formula: C20H22O8. Mole weight: 390.38.
Leptocillin
Leptocillin is extracted from Leptoaphaeria sp. L-179. It is resistant to several Gram-positive bacteria (Staphylococcus aureus 209P, Bacillus subtilis No. 119) and several Gram-negative bacteria (Klebsiella pneumoniae 22 # 3038, proteus singular GN310). Synonyms: Antibiotic MK4588; MK 4588; MK-4588; 7-(1-Isocyano-2-(4-methoxyphenyl))ethenyl-1-hydroxy-7-isocyanobicyclo(4,2,0)oct-2-en-4-one. CAS No. 123949-57-5. Molecular formula: C19H16N2O3. Mole weight: 320.34.
Leptofuranin A
It is produced by the strain of Str. tanashiensis. At low concentrations, it causes the stagnation of normal cells, but it can cause the death of transformed cells. Molecular formula: C32H48O5. Mole weight: 512.72.
Leptofuranin B
It is produced by the strain of Str. tanashiensis. At low concentrations, it causes the stagnation of normal cells, but it can cause the death of transformed cells. Molecular formula: C33H50O5. Mole weight: 526.75.
Leptofuranin C
It is produced by the strain of Str. tanashiensis. At low concentrations, it causes the stagnation of normal cells, but it can cause the death of transformed cells. Molecular formula: C32H46O5. Mole weight: 510.70.
Leptofuranin D
It is produced by the strain of Str. tanashiensis. At low concentrations, it causes the stagnation of normal cells, but it can cause the death of transformed cells. Molecular formula: C33H48O5. Mole weight: 524.73.
Leptolstatin
It is produced by the strain of Str. sp. SAM1595. It has no activity against bacteria, fungi and yeast, in addition to Millet wine schizozoite yeast (MIC is 0.4 μg/mL). It has a strong inhibitory effect on mammalian cells, such as normal fibroblast 3Y1 cells in rats (IC50 is 0.4 ng/mL). Synonyms: 2H-Pyran-2-one, 6-[(1E,3Z,5R,7E,9E,11R,13S,14R,15S,17E)-14,19-dihydroxy-3,5,9,11,13,15,17-heptamethyl-12-oxo-1,3,7,9,17-nonadecapentaen-1-yl]-5,6-dihydro-, (6R)-; (R)-6-((1E,3Z,5R,7E,9E,11R,13S,14R,15S,17E)-14,19-dihydroxy-3,5,9,11,13,15,17-heptamethyl-12-oxononadeca-1,3,7,9,17-pentaen-1-yl)-5,6-dihydro-2H-pyran-2-one. CAS No. 149633-91-0. Molecular formula: C31H46O5. Mole weight: 498.69.
Leptosin I
It is produced by the strain of I Leptosphaeria sp. OUPS-4. In order to understand its cytotoxic effects, someone tested Leukemia lymphocyte P388 in culture with an ED50 of 1.13 μg/mL. Synonyms: Chaetocin, 2,5:2',5'-dide(epidithio)-19'-deoxy-2',5'-(epitetrathio)-5,6'-epoxy-6-hydroxy-19',19'-dimethyl-, (5alpha,6S,6'S,15alpha)-; (+)-Leptosin I; 22bH-18,22a-(Iminomethano)-10b,23a-methano-10bH,23aH-indolo[2'',3'':2',3'][1,2,3,4,6]tetrathiazocino[6'',5'':1',5']pyrrolo[3',4':6,7]pyrazino[2''',1''':2,3][1,3]oxazepino[4,5-b]indole-1,4,17,25(18H)-tetrone,2,3,5a,6,15,15a-hexahydro-24-hydroxy-3-(hydroxymethyl)-2,26-dimethyl-18-(1-methylethyl)-, (3a,5ab,10ba,10cS*,15ab,18b,22ab,22ba,23aa,24S*)-(+)-; Leptosine I. CAS No. 160472-96-8. Molecular formula: C32H32N6O7S4. Mole weight: 740.89.
Leptosin J
It is produced by the strain of J Leptosphaeria sp. OUPS-4. In order to understand its cytotoxic effects, someone tested Leukemia lymphocyte P388 in culture with an ED50 of 1.25 μg/mL. Synonyms: Chaetocin, 2,5:2',5'-dide(epidithio)-19'-deoxy-2',5'-(epitetrathio)-5,6'-epoxy-6-hydroxy-19',19'-dimethyl-, (2alpha,5alpha,6S,6'S,15alpha)-; 22bH-18,22a-(Iminomethano)-10b,23a-methano-10bH,23aH-indolo[2'',3'':2',3'][1,2,3,4,6]tetrathiazocino[6'',5'':1',5']pyrrolo[3',4':6,7]pyrazino[2''',1''':2,3][1,3]oxazepino[4,5-b]indole-1,4,17,25(18H)-tetrone,2,3,5a,6,15,15a-hexahydro-24-hydroxy-3-(hydroxymethyl)-2,26-dimethyl-18-(1-methylethyl)-, (3a,5aa,10bb,10cR*,15aa,18a,22aa,22bb,23ab,24R*)-(+)-; Leptosine J. CAS No. 160550-15-2. Molecular formula: C32H32N6O7S4. Mole weight: 740.89.
Leucanicidin
It is produced by the strain of Streptomyces. It is a potent nematocide and insecticide belonging to the bafilomycin class. It also has anti-fungal properties. Synonyms: (3Z,5E,7R,8S,9S,11E,13E,15S,16R)-16-[(1S,2R,3S)-3-[(2R,4R,5S,6R)-4-[(6-deoxy-2-O-methyl-α-L-mannopyranosyl)oxy]tetrahydro-2-hydroxy-5-methyl-6-(1-methylethyl)-2H-pyran-2-yl]-2-hydroxy-1-methylbutyl]-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyl-oxacyclohexadeca-3,5,11,13-tetraen-2-one; 21-O-De(3-carboxy-1-oxo-2-propenyl)-2-demethyl-21-O-(6-deoxy-2-O-methyl-α-L-mannopyranosyl)-2-methoxy-24-methylhygrolidin. Grade: >95% by HPLC. CAS No. 91021-66-8. Molecular formula: C42H70O13. Mole weight: 783.00.
Leucinostatin B
It is produced by the strain of Paecilomyces lilacinus A-267. It's a peptide antibiotic. It has a strong anti-pathogenic and non-pathogenic yeast and fungi activity, but also has a medium anti-bacterial effect. It was previously reported that Leucinostatin A and B mixtures inhibited HeLa cells. 0.05 μg/mL of Leucinostatin B for a week (0.25 mg/kg?d) has inhibitory effect on the airy ascites carcinoma entity type, and for ascites type is invalid. Synonyms: Paecilotoxin B; Leucinostatin A, 9-[N-[1-methyl-2-(methylamino)ethyl]-b-alaninamide]-, [9(S)]-; Antibiotic 1907-II; b-Alaninamide, cis-4-methyl-1-(4-methyl-1-oxo-2-hexenyl)-L-prolyl-(4S,6S)-6-hydroxy-4-methyl-8-oxo-L-2-aminodecanoyl-threo-3-hydroxy-L-leucyl-2-methylalanyl-L-leucyl-L-leucyl-2-methylalanyl-2-methylalanyl-N-[1-methyl-2-(methylamino)ethyl]-, [1[S-(E)],9(S)]-. Grade: >95%. CAS No. 76663-52-0. Molecular formula: C61H109N11O13. Mole weight: 1204.58.
Leucinostatin D
It is produced by the strain of Paecilomyces marquandii. It's a peptide antibiotic. It has anti-gram-positive bacterial and fungal effects. It has in vitro cytotoxic activity against HeLa 850, KB cells and sensitive leukemia cells P388 with ID50 of 1.00 ng/mL. Synonyms: Paecilotoxin D; (4R)-N-[1-[[2-hydroxy-3-methyl-1-[2-[[3-methyl-1-[[3-methyl-1-[2-[2-[2-(1-methylaminopropan-2-ylcarbamoyl)ethylcarbamoyl]propan-2-ylcarbamoyl]propan-2-ylcarbamoyl]butyl]carbamoyl]butyl]carbamoyl]propan-2-ylcarbamoyl]butyl]carbamoyl]-3-methyl-butyl]-4-methyl-1-[(E,4S)-4-methylhex-2-enoyl]pyrrolidine-2-carboxamide. CAS No. 100334-47-2. Molecular formula: C56H101N11O11. Mole weight: 1104.47.
Leucinostatin H
It is produced by the strain of Paecilomyces marquandii. It's a peptide antibiotic. It has anti-gram-positive bacterial and fungal effects. Synonyms: Paecilotoxin H; N-(1-(aminooxy)-26-(1-hydroxy-2-methylpropyl)-17,20-diisobutyl-4,11,11,14,14,23,23,31-octamethyl-6,10,13,16,19,22,25,28-octaoxo-5,9,12,15,18,21,24,27-octaazadotriacontan-29-yl)-4-methyl-1-((R,E)-4-methylhex-2-enoyl)pyrrolidine-2-carboxamide; Leucinostatin A, 2-L-leucine, N9-oxide. CAS No. 109539-58-4. Molecular formula: C57H103N11O12. Mole weight: 1134.49.
Leucinostatin K
It is produced by the strain of Paecilomyces marquandii. It's a peptide antibiotic. It has anti-gram-positive bacterial and fungal effects. Synonyms: Leucinostatin A, N9-oxide; b-Alaninamide, cis-4-methyl-1-(4-methyl-1-oxo-2-hexenyl)-L-prolyl-(4S,6S)-6-hydroxy-4-methyl-8-oxo-L-2-aminodecanoyl-threo-3-hydroxy-L-leucyl-2-methylalanyl-L-leucyl-L-leucyl-2-methylalanyl-2-methylalanyl-N-[2-(dimethylamino)-1-methylethyl]-, N9-oxide, [1[S-(E)],9(S)]-; N-(1-(aminooxy)-33-hydroxy-26-(1-hydroxy-2-methylpropyl)-17,20-diisobutyl-4,11,11,14,14,23,23,31-octamethyl-6,10,13,16,19,22,25,28,35-nonaoxo-5,9,12,15,18,21,24,27-octaazaheptatriacontan-29-yl)-4-methyl-1-((R,E)-4-methylhex-2-enoyl)pyrrolidine-2-carboxamide. CAS No. 109539-57-3. Molecular formula: C62H111N11O14. Mole weight: 1234.61.
Leucomentin-5
It is produced by the strain of Paxillus panuoides. It is a free radical scavenger. It has strong inhibitory effect of lipid peroxidation with IC50 of 0.11 μg/mL. The IC50 of reference Leucomentin-2 is 0.06 μg/mL. Molecular formula: C38H34O13. Mole weight: 698.67.
Leucomentin-6
It is produced by the strain of Paxillus panuoides. It is a free radical scavenger. It has strong inhibitory effect of lipid peroxidation with IC50 of 0.06 μg/mL. The IC50 of reference Leucomentin-4 is 0.11 μg/mL. Molecular formula: C42H38O13. Mole weight: 750.74.
Leucomycin A6
Leucomycin A6 is a main component of YL-704, a macrolide antibiotic complex isolated from Streptomyces platensis subsp. malvinus. It is active against gram-positive bacteria. Synonyms: YL-704B3; YL 704B3; YL 704 B3; Platenomycin-B3. CAS No. 18361-48-3. Molecular formula: C40H65NO15. Mole weight: 799.9.
Leucomycin U
It is produced by the strain of Str. kitasatoensis. It's a macrolide antibiotic. It has strong anti-gram-positive bacterial effect, and also has an effect on spirochetes, rickettsium and Chlamydia. After the C3 position on the lactone ring in the structure is acetylated, the activity in vitro is reduced, but the activity in vivo is enhanced, and the toxicity is also reduced. The antibacterial activity of Leucomycin group A is stronger than group B. It has been used in clinical and the indications are the same as erythromycin. Synonyms: Deisovaleryl josamycin; Deisovaleryl leucomycin A3; Leucomycin V 3-acetate; 4''-Deisovaleryljosamycin. CAS No. 31642-61-2. Molecular formula: C37H61NO14. Mole weight: 743.88.
Leucyl-lysine is a dipeptide composed of leucine and lysine. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: L-Lysine, L-Leucyl-; (S)-6-Amino-2-((S)-2-amino-4-methylpentanamido)hexanoic acid; L-leucyl-L-lysine; H-LK-OH; Leu-Lys; L-Leu-L-Lys. Grade: ≥95%. CAS No. 6416-76-8. Molecular formula: C12H25N3O3. Mole weight: 259.35.
It is produced by the strain of Bacillus laterosporus BMI 156-14F1. It inhibits aminopeptidase M with IC50 of 0.2 μg/mL. It has no antimicrobial effects (100 μg/mL). Synonyms: Leuhistine; (2R,3S)-2-((1H-imidazol-4-yl)methyl)-3-amino-2-hydroxy-5-methylhexanoic acid; 1H-Imidazole-4-propanoic acid, alpha-(1-amino-3-methylbutyl)-alpha-hydroxy-, (R-(R*,S*))-. Grade: 95%. CAS No. 129085-76-3. Molecular formula: C11H19N3O3. Mole weight: 241.29.
Leuseramycin
It is produced by the strain of Str. hygroscopicus TM-531. It's a polyether antibiotic. It has anti-gram-positive bacteria, plant pathogenic bacteria and some protozoa effects. Synonyms: (2R,4S,8R,E)-8-((2R,2'S,4'S,5R,5'S,7S,7'S,8S,9S,9'R,10'S)-9-hydroxy-2'-((2S,3S,5S,6S)-6-hydroxy-3,5,6-trimethyltetrahydro-2H-pyran-2-yl)-9'-(((2R,5R,6R)-5-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2,4',8,10'-tetramethyl-1,1',6,6'-tetraoxa[2,7'-bispiro[4.5]decan]-7-yl)-2,4,6-trimethyl-5-oxonon-6-enoic acid; 30-Deoxydianemycin; Antibiotic TM-531; TM-531. Grade: 95%. CAS No. 73537-10-7. Molecular formula: C47H78O13. Mole weight: 851.12.
Lexithromycin
It is an early semi-synthetic erythromycin, prepared by reaction of the 9-keto moiety to methyl oxime. It shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal sub-units, blocking protein synthesis. Synonyms: Erythromycin A 9-methoxime; Wy 48314; Erythromycin A 9-(O-methyloxime); 9-deoxo-9-methoxyiminoerythromycin A; Azithromycin Impurity 4. Grade: >98% by HPLC. CAS No. 53066-26-5. Molecular formula: C38H70N2O13. Mole weight: 762.97.
L-Glutaminol. CAS No. 40217-15-0. Molecular formula: C5H12N2O2. Mole weight: 132.16.
L-Glutamyl-L-Proline
L-Glutamyl-L-Proline is a dipeptide composed of glutamate and proline. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: L-Proline, L-a-glutamyl-; L-α-Glutamyl-L-proline; Glutamyl-proline; L-Proline, L-alpha-glutamyl-; Glu-Pro; glutamylproline; H-EP-OH. Grade: ≥98%. CAS No. 41745-47-5. Molecular formula: C10H16N2O5. Mole weight: 244.24.
Lichenysin G
It is produced by the strain of Bacillus licheniformis IM 1307. It acts as a surfactant and is 10 times more active than Surfactin. Molecular formula: C42H72N8O12. Mole weight: 881.06.
Lichexanthone
Lichexanthone is separated from the bark of Cupania cinerea. It has a role as a plant metabolite. CAS No. 15222-53-4. Molecular formula: C16H14O5. Mole weight: 286.28.
Lignosulfonic acid sodium salt
Lignosulfonic acid sodium salt is a lignin-derived macromolecule with antiviral activity and can effectively resist HIV and HSV in vitro. Uses: Used as a dispersant, emulsion stabilizer, chelator, and ore flotation agent; also used to enhance pcbs biodegradation, as a concrete additive, in oil well drilling muds, as a soil stabilizer and road binder, to modify viscosity of molasses in animal feeds, as a binder (ceramics, bricks, and refractories), and as a veterinary medication. Synonyms: Sodium lignosulfonate; Vanisperse. CAS No. 8061-51-6.