BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Lysyl-phenylalanine | Lysyl-phenylalanine is a dipeptide composed of lysine and phenylalanine. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: lysylphenylalanine; L-Phenylalanine, L-lysyl-; H-KF-OH; Lys-phe; L-lysyl-L-phenylalanine; L-Lys-L-Phe; L-Phenylalanine, N-L-lysyl-; N-(2,6-Diamino-1-hydroxyhexylidene)phenylalanine. Grade: ≥95%. CAS No. 6235-35-4. Molecular formula: C15H23N3O3. Mole weight: 293.36. |  |
| Lysyl-serine | Lysyl-serine is a dipeptide composed of lysine and serine. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: Lys-Ser; L-Serine, L-lysyl-; H-KS-OH; L-lysyl-L-serine; L-Serine, N-L-lysyl-; T Cell modulatory peptide. Grade: >90%. CAS No. 6665-19-6. Molecular formula: C9H19N3O4. Mole weight: 233.26. | |
| Lysyl-threonine | Lysyl-threonine is a dipeptide composed of lysine and threonine. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: H-KT-OH; L-lysyl-L-threonine; lysylthreonine; L-Threonine, L-lysyl-; Lys-Thr; L-Threonine, N-L-lysyl-; L-Lys-L-Thr. Grade: >90% by HPLC. CAS No. 97791-84-9. Molecular formula: C10H21N3O4. Mole weight: 247.29. | |
| M-13-1 | It is an anthracycline antibiotic derived from Nocardia brasiliensis IFM-0075. Synonyms: 4,11-Dihydroxy-2,8-dimethyl-7-methoxynaphthacene-5,12-dione. Molecular formula: C21H16O5. Mole weight: 348.35. | |
| M-230B | M-230B is originally isolated from Myxococcus xanthus M516E. It has anti-gram-negative and weak anti-gram-positive activity. Molecular formula: C35H59NO8. Mole weight: 621.84. | |
| M-4365 A1 | It is produced by the strain of Micromonospora capillate MCRL 0940. M-4365 A1 is mainly resistant to Gram-positive bacteria and mycoplasma, and cross-resistance with other macrolide antibiotics. Molecular formula: C31H53NO8. Mole weight: 567.75. | |
| M-4365 G1 | It is produced by the strain of Micromonospora capillate MCRL 0940. M-4365 G1 is mainly resistant to Gram-positive bacteria and mycoplasma, and cross-resistance with other macrolide antibiotics. And it also has a certain anti-Gram-negative bacteria activity. Molecular formula: C31H53NO7. Mole weight: 551.75. | |
| M-4365 G2 | It is produced by the strain of Micromonospora capillate MCRL 0940. M-4365 G2 is mainly resistant to Gram-positive bacteria and mycoplasma, and cross-resistance with other macrolide antibiotics. Synonyms: SCHEMBL192993. Molecular formula: C31H51NO8. Mole weight: 565.74. | |
| MA144 G2 | MA144 G2 is originally isolated from Streptomyces galilaeus MA144M1. It has anti-gram-positive bacteria and tumor effects. Synonyms: Antibiotic MA 144G2; 1-Naphthacenecarboxylic acid, 1,2,3,4,6,11-hexahydro-6,11-dioxo-2-ethyl-4-O-((2,3,6-trideoxy-alpha-L-glycero-hexopyranos-4-ulosyl-(1-4)-O-2,6-dideoxy-alpha-L-lyxo-hexopyranosyl(1-4)-O-3-(dimethylamino)-2,3,6-trideoxy-alpha-L-hexopyranosyl)oxy)-2,5,7,10-tetrahydroxy-, methyl ester. CAS No. 66808-28-4. Molecular formula: C42H53NO16. Mole weight: 827.87. | |
| MA144 M1 | MA144 M1 is originally isolated from Streptomyces galilaeus MA144M1. It has anti-gram-positive bacteria and tumor effects. Synonyms: Antibiotic MA 144M1; 1-Naphthacenecarboxylic acid, 1,2,3,4,6,11-hexahydro-6,11-dioxo-2-ethyl-4-((O-2,3,6-trideoxy-alpha-L-glycero-hexopyranosyl-(1-4)-O-2,6-dideoxy-alpha-L-lyxo-hexopyranosyl-(1,4)-2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-2,5,7-trihydroxy-, methyl ester; aclacinomycin M; MA-144M1. CAS No. 64431-68-1. Molecular formula: C42H55NO15. Mole weight: 813.88. | |
| MA144 M2 | MA144 M2 is originally isolated from Streptomyces galilaeus MA144M1. It has anti-gram-positive bacteria and tumor effects. Synonyms: Antibiotic MA 144M2; 1-Hydroxy MA144 M1; 1-Naphthacenecarboxylic acid, 1,2,3,4,6,11-hexahydro-6,11-dioxo-2-ethyl-2,5,7,10-tetrahydroxy-4-((O-2,3,6-trideoxy-alpha-L-glycero-hexopyranosyl-(1-4)-O-2,6-dideoxy-alpha-L-lyxo-hexopyranosyl-(1-4) 2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-, methyl ester; MA-144M2. CAS No. 64474-89-1. Molecular formula: C42H55NO16. Mole weight: 829.88. | |
| MA144 S1 | MA144 S1 is originally isolated from Streptomyces galilaeus MA144M1. It has anti-gram-positive bacteria and tumor effects. Synonyms: aclacinomycin S; Antibiotic MA 144S1; MA 144 S1; L-2-Deoxyfucosyl-L-rhodosaminyl-aklavinone. CAS No. 64431-69-2. Molecular formula: C36H45NO13. Mole weight: 699.74. | |
| MA144 U1 | MA144 U1 is originally isolated from Streptomyces galilaeus MA144M1. It has anti-gram-positive bacteria and tumor effects. Synonyms: Antibiotic MA 144U1; 1-Naphthacenecarboxylic acid, 1,2,3,4,6,11-hexahydro-6,11-dioxo-2-ethyl-4-O-((2,6-dideoxy-alpha-L-lyxo-hexopyranosyl(1-4)-O-2,6-dideoxy-alpha-L-lyxo-hexopyranosyl(1-4)-O-3-(dimethylamino)-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-2,7-dihydroxy-, methyl ester. CAS No. 65222-74-4. Molecular formula: C42H55NO16. Mole weight: 829.88. | |
| Macquarimicin A | It is produced by the strain of Micromonospora chalcea. It's an antibiotic. Synonyms: 2,5-Ethanoindeno[4,5-e]oxecin-3,11,15-trione,5,6,7,8,8a,10a,12,13,13a,13b-decahydro-7-hydroxy-12-methyl-, (1Z,5R*,7R*,8aS*,10aS*,12R*,13aR*,13bS*)-(+)-. CAS No. 165561-14-8. Molecular formula: C19H22O5. Mole weight: 330.37. | |
| Macquarimicin B | It is produced by the strain of Micromonospora chalcea. It's an antibiotic. Synonyms: 3H-5,2-Ethanylylideneindeno[4,5-e]oxecin-3,11(1H)-dione,5,6,7,8,8a,10a,12,13,13a,13b-decahydro-7,15-dihydroxy-12-methyl-1-(2-oxopropyl)-, (1S,5R,7R,8aS,10aS,12R,13aR,13bS)-; 3H-5,2-Ethanylylideneindeno[4,5-e]oxecin-3,11(1H)-dione,5,6,7,8,8a,10a,12,13,13a,13b-decahydro-7,15-dihydroxy-12-methyl-1-(2-oxopropyl)-, [1S-(1R*,5S*,7S*,8aR*,10aR*,12S*,13aS*,13bR*)]-; 1H-2,5-Ethanoindeno[4,5-e]oxecin-3,11-dione,5,6,7,8,8a,10a,12,13,13a,13b-decahydro-7,15-dihydroxy-12-methyl-1-(2-oxopropyl)-, (1S,5R,7R,8aS,10aS,12R,13aR,13bS)-. CAS No. 165561-13-7. Molecular formula: C22H28O6. Mole weight: 388.45. | |
| Macquarimicin C | It is produced by the strain of Micromonospora chalcea. It's an antibiotic. Synonyms: 2H-8,10a-Ethanocyclopenta[7,8]naphtho[2,3-c]pyran-3,10,12-trione,1,3a,5a,6,6a,7,8,11,11a,11b-decahydro-2-methyl-11-(2-oxopropyl)-,(2R,3aS,5aS,6aS,8R,10aR,11S,11aS,11bR)-; 10H-8,10a-Ethanocyclopenta[7,8]naphtho[2,3-c]pyran-3,10,12(2H)-trione,1,3a,5a,6,6a,7,8,11,11a,11b-decahydro-2-methyl-11-(2-oxopropyl)-, (2R,3aS,5aS,6aS,8R,10aR,11S,11aS,11bR)-. CAS No. 165561-12-6. Molecular formula: C22H26O5. Mole weight: 370.44. | |
| Macrosphelide L | It is produced by the strain of Periconia byssoides OUPS-N133. It is a cell adhesion inhibitor. It inhibits the adhesion of HL-60 cells to HU-VEC cells with IC50 of 5.6 μmol/L. Molecular formula: C16H22O8. Mole weight: 342.34. | |
| Madindoline A | It is produced by the strain of Str. sp. K93-0711. It is an interleukin-6 inhibitor. It inhibits IL-6-dependent MH-60 cells and has no inhibitory effect on IL-6-independent MH-60 cells. In the presence of 0.1 U/mL IL-6, it inhibits IL-6-dependent MH-60 cells with IC50 of 8 μmol/L. It has no antimicrobial effect. Synonyms: Antibiotic K93-0711 I1; (+)-madindoline A; Madindoline; 4-cyclopentene-1,3-dione, 4-butyl-2,5-dimethyl-2-[[(3aR,8aS)-2,3,3a,8a-tetrahydro-3a-hydroxy-8H-furo[2,3-b]indol-8-yl]methyl]-, (2R)-; (2R)-4-Butyl-2,5-dimethyl-2-[[(3aR,8aS)-2,3,3a,8a-tetrahydro-3a-hydroxy-8H-furo[2,3-b]indole-8-yl]methyl]cyclopenta-4-ene-1,3-dione. CAS No. 184877-64-3. Molecular formula: C22H27NO4. Mole weight: 369.45. | |
| Madindoline B | It is produced by the strain of Str. sp. K93-0711. It is an interleukin-6 inhibitor. It inhibits IL-6-dependent MH-60 cells and has no inhibitory effect on IL-6-independent MH-60 cells. In the presence of 0.1 U/mL IL-6, it inhibits IL-6-dependent MH-60 cells with IC50 of 30 μmol/L. It has no antimicrobial effect. Synonyms: Antibiotic K93-0711 I2; (S)-4-butyl-2-(((3aR,8aS)-3a-hydroxy-2,3,3a,8a-tetrahydro-8H-furo[2,3-b]indol-8-yl)methyl)-2,5-dimethylcyclopent-4-ene-1,3-dione; (+)-Madindoline B. CAS No. 184877-65-4. Molecular formula: C22H27NO4. Mole weight: 369.45. | |
| Madumicin II | It is a cyclic depsipeptide antibiotic produced by the strain of Actinoplanes philippinences NRRL 5462. It mainly has the activity of anti-Gram-positive bacteria. Synonyms: Antibiotic A-2315; A-2315A; Antibiotic A 2315A; Madumycin I, 15-deoxo-15-hydroxy-, (15S)-; A2315A; Madumycin II; Antibiotic A 17002F; Antibiotic A 15104V. CAS No. 58717-24-1. Molecular formula: C26H37N3O7. Mole weight: 503.59. | |
| Malformin C | Malformin C is a fungal cyclic pentapeptide with antibacterial and anticancer activities. Study shows that Malformin C inhibits cell growth in Colon 38 and HCT 116 cells in a dose-dependent manner with IC50 of 0.27±0.07μM and 0.18±0.023μM, respectively. Synonyms: Malformin B1b; Cyclo(D-cysteinyl-D-cysteinyl-L-valyl-D-leucyl-L-leucyl)? Cyclic (1→2)?-Disulfide; (-)-cyclo[D-Cys(1)-D-Cys(1)-L-Val-D-Leu-L-Leu-]. Grade: ≥95%. CAS No. 59926-78-2. Molecular formula: C23H39N5O5S2. Mole weight: 529.72. | |
| Maltophilin | It is produced by the strain of Stenotrophomonas maltophilia. It is a broad-spectrum antifungal antibiotic that has no antibacterial effect against gram-positive and gram-negative bacteria. Molecular formula: C29H38N2O6. Mole weight: 510.62. | |
| Mancozeb | Mancozeb is a fungicide used to protect crops in agriculture. Synonyms: Manganese Zinc ethylenebis(dithiocarbamate). CAS No. 8018-1-7. Molecular formula: C8H12MnN4S8Zn. Mole weight: 541.1. | |
| Maniwamycin A | It is produced by the strain of Str. prasinopilosus KC-7367. It has anti-fungal effect. Maniwamycin A has stronger anti-fungal effect than Maniwamycin B, but it has no anti-bacterial effect. Synonyms: Antibiotic KA 7367A; KA 7367A; (S-(Z,E))-3-(1-Hexenyl-ONN-azoxy)-2-butanone. CAS No. 122566-70-5. Molecular formula: C10H18N2O2. Mole weight: 198.26. | |
| Maniwamycin B | It is produced by the strain of Str. prasinopilosus KC-7367. It has anti-fungal effect. Maniwamycin B has weaker anti-fungal effect than Maniwamycin A, but it has no anti-bacterial effect. Synonyms: Antibiotic KA 7367B; KA 7367B; (S-(R*,R*-(Z,E)))-3-(1-Hexenyl-ONN-azoxy)-2-butanol; 2-Butanol, 3-(1-hexenyl-ONN-azoxy)-, (S-(R*,R*-(Z,E)))-. CAS No. 122547-71-1. Molecular formula: C10H20N2O2. Mole weight: 200.28. | |
| Mannosylglucosaminide | It is produced by the strain of Str. virginiae var. 4243-MTt1. It's an aminoglycoside antibiotic. It has anti-bacterium, mycobacterium and beer yeast effects. Trehalose does not counteract its antibacterial effect against Mycobacterium 607. Synonyms: Mannosyl glucosaminide; Antibiotic 4243; 1-O-(2-Amino-2-deoxy-α-D-gluco-hexopyranosyl)-α-D-manno-hexopyranose; Mannotrehalosamine. CAS No. 14510-04-4. Molecular formula: C12H23NO10. Mole weight: 341.31. | |
| Manumycin E | It is produced by the strain of Str. sp. WB-83. It has anti-gram-positive bacteria and Escherichia coli effects, but the effect is very weak against other anti-gram-negative bacteria, and has no effect on fungi. It inhibits RAS Faraday base transfer with IC50 of 5 μmol/L. It has weak cytotoxic activity against human cloned cancer cell lines HCT-116 (IC50 is 15.6 μg/mL). Synonyms: Asukamycin E; 2,4,6-Undecatrienamide, N-[(1S,5S,6R)-5-hydroxy-5-[(1E,3E,5E)-7-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-7-oxo-1,3,5-heptatrienyl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-10-methyl-, (2E,4E,6E)-. CAS No. 156250-43-0. Molecular formula: C30H34N2O7. Mole weight: 534.61. | |
| Manumycin F | It is produced by the strain of Str. sp. WB-83. It has anti-gram-positive bacteria and Escherichia coli effects, but the effect is very weak against other anti-gram-negative bacteria, and has no effect on fungi. It inhibits RAS Faraday base transfer with IC50 of 5 μmol/L. It has weak cytotoxic activity against human cloned cancer cell lines HCT-116 (IC50 is 15.6 μg/mL). Synonyms: Asukamycin; asukamycin A1; 2,4,6-Heptatrienamide, 7-cyclohexyl-N-[5-hydroxy-5-[7-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-7-oxo-1,3,5-heptatrienyl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-. CAS No. 156317-47-4. Molecular formula: C31H34N2O7. Mole weight: 546.62. | |
| Manumycin G | It is produced by the strain of Str. sp. WB-83. It has anti-gram-positive bacteria and Escherichia coli effects, but the effect is very weak against other anti-gram-negative bacteria, and has no effect on fungi. It inhibits RAS Faraday base transfer with IC50 of 5 μmol/L. It has weak cytotoxic activity against human cloned cancer cell lines HCT-116 (IC50 is 15.6 μg/mL). Synonyms: 2,4,6-Nonatrienamide, N-[(1S,5S,6R)-5-hydroxy-5-[(1E,3E,5E)-7-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-7-oxo-1,3,5-heptatrienyl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-8-methyl-, (2E,4E,6E)-; 2,4,6-Nonatrienamide, N-[5-hydroxy-5-[7-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-7-oxo-1,3,5-heptatrienyl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-8-methyl-, [1S-[1a,3(2E,4E,6E),5b,5(1E,3E,5E),6a]]-. Grade: ≥95%. CAS No. 156250-44-1. Molecular formula: C28H30N2O7. Mole weight: 506.55. | |
| Marasmic acid | It is produced by the strain of Marasmius conigenus 6890. It's a terpene antibiotic. It has anti-gram-positive bacteria effect. It also has anti-gram-negative bacteria, mycobacteria and fungi effect, but the effect is weak. Synonyms: 3H,6H-3a,8b-Methano-1H-indeno[4,5-c]furan-4-carboxaldehyde,5a,7,8,8a-tetrahydro-3-hydroxy-7,7-dimethyl-1-oxo-, [3S-(3a,3ab,5ab,8ab,8bb)]-; NSC 318506; (3S,3aR,5aR,8aS,8bS)-3-hydroxy-7,7-dimethyl-1-oxo-5a,7,8,8a-tetrahydro-1H,3H,6H-3a,8b-methanoindeno[4,5-c]furan-4-carbaldehyde. CAS No. 2212-99-9. Molecular formula: C15H18O4. Mole weight: 262.30. | |
| Marcellomycin | Marcellomycin is produced by the strain of Actinosporangium bohemicum sp. nov. C-36145. It is a glycoside and quinone antibiotic. It has anti-gram-positive bacteria effect, especially has strong effect on streptococcus. It also has effect on individual gram-negative bacteria, but the activity is not strong. Marcellomycin was 4 times stronger than Musettamycin in the treatment of leukemia L-1210. Synonyms: Morcellomycin; Pyrromycin; Mar; Rhodirubin E; Antibiotic MA 144U2; 1-Naphthacenecarboxylic acid, 4-((O-2,6-dideoxy-alpha-L-lyxo-hexopyranosyl-(1-4)-O-2,6-dideoxy-alpha-L-lyxo-hexopyranosyl-(1-4)-2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7,10-tetrahydroxy-6,11-dioxo-, methyl ester, (1R-(1-alpha,2-beta,4-beta))-. CAS No. 63710-10-1. Molecular formula: C42H55NO17. Mole weight: 845.89. | |
| Marcfortine A | It is an indole alkaloid isolated from Aspergillus and Penicillium species. It has strong nematicidal activity. It is structurally related to paracetamol and can act by preventing cholinergic neuromuscular transmission. Synonyms: UK 111866. Grade: >99% by HPLC. CAS No. 75731-43-0. Molecular formula: C28H35N3O4. Mole weight: 477.59. | |
| Maridomycin II | It is produced by the strain of Str. hygroscopicus B-5050. It's a macrolide antibiotic. It has the activity against gram-positive bacteria and mycoplasma. It has anti-mycobacterial effect but the effect is not strong. Serum dose not affect its antibacterial activity. It has the effect of protecting gram-positive bacterial infection mice, and the therapeutic dose is similar to styloleomycin. Synonyms: 9-Dihydrocarbomycin A; Antibiotic B 5050B; B 5050B; Antibiotic YL 704C4; Leucomycin V, 12,13-dihydro-12,13-epoxy-, 3-acetate 4B-(3-methylbutanoate), (12S,13S)-. Grade: ≥95%. CAS No. 35908-45-3. Molecular formula: C42H69NO16. Mole weight: 843.99. | |
| Maridomycin III | It is produced by the strain of Str. hygroscopicus B-5050. It's a macrolide antibiotic. It has the activity against gram-positive bacteria and mycoplasma. Serum dose not affect its antibacterial activity. It has the effect of protecting gram-positive bacterial infection mice, and the therapeutic dose is similar to styloleomycin. Synonyms: Platenomycin C1; Leucomycin V, 12,13-epoxy-12,13-dihydro-, 3,4B-dipropanoate, (12S,13S)-; Antibiotic B 5050C; Antibiotic YL 704C1; Turimycin EP3; Maridomycine; Maridomycinum. Grade: ≥95%. CAS No. 35775-82-7. Molecular formula: C41H67NO16. Mole weight: 829.97. | |
| Maridomycin IV | It is produced by the strain of Str. hygroscopicus B-5050. It's a macrolide antibiotic. It has the activity against gram-positive bacteria and mycoplasma. Serum dose not affect its antibacterial activity. It has the effect of protecting gram-positive bacterial infection mice, and the therapeutic dose is similar to styloleomycin. Synonyms: Antibiotic B 5050D; Turimycin EA3; Leucomycin V, 12,13-dihydro-12,13-epoxy-, 3-acetate 4B-propanoate, (12S,13S)-. Grade: ≥95%. CAS No. 35942-56-4. Molecular formula: C40H65NO16. Mole weight: 815.94. | |
| Maridomycin V | It is produced by the strain of Str. hygroscopicus B-5050. It's a macrolide antibiotic. It has the activity against gram-positive bacteria and mycoplasma. Serum dose not affect its antibacterial activity. It has the effect of protecting gram-positive bacterial infection mice, and the therapeutic dose is similar to styloleomycin. Synonyms: Antibiotic B 5050E; Turimycin EP2; Leucomycin V, 12,13-dihydro-12,13-epoxy-, 4B-acetate 3-propanoate, (12S,13S)-. Grade: ≥95%. CAS No. 35942-57-5. Molecular formula: C40H65NO16. Mole weight: 815.94. | |
| Maridomycin VI | It is produced by the strain of Str. hygroscopicus B-5050. It's a macrolide antibiotic. It has the activity against gram-positive bacteria and mycoplasma. Serum dose not affect its antibacterial activity. It has the effect of protecting gram-positive bacterial infection mice, and the therapeutic dose is similar to styloleomycin. Synonyms: Antibiotic B 5050F; B 5050F; Leucomycin V, 12,13-dihydro-12,13-epoxy-, 3,4B-diacetate, (12S,13S)-. Grade: ≥95%. CAS No. 35775-66-7. Molecular formula: C39H63NO16. Mole weight: 801.92. | |
| Marilactone | Marilactone is produced from the fungus Stachylidium sp. Synonyms: 2H-Pyran-2-one, 6-ethyl-4-hydroxy-3-methyl-; 3-Methyl-4-hydroxy-6-ethyl-2-pyron. Grade: ≥98%. CAS No. 34818-17-2. Molecular formula: C8H10O3. Mole weight: 154.16. | |
| Mathemycin A | It is produced by the strain of Act. sp. HIL Y-862O. It has an inhibitory effect on pathogenic fungi. It inhibits the Phytophthora infestans JO8 in vitro (MIC is 7.8 μg/mL), and it inhibits JO8 in greenhouse (LD50 is 42 X 10-6, LC90 is 500 X 10-6). Molecular formula: C71H132N2O24. Mole weight: 1397.80. | |
| Mathemycin B | It is produced by the strain of Act. sp. HIL Y-862O. It has an inhibitory effect on pathogenic fungi. It inhibits the Phytophthora infestans JO8 in vitro (MIC is 7.8 μg/mL), and it inhibits JO8 in greenhouse (LD50 is 42 X 10-6, LC90 is 500 X 10-6). Molecular formula: C77H142N2O29. Mole weight: 1559.94. | |
| Matlystatin A | It is produced by the strain of Actinomadura atramentaria. It's a Type V collagenase inhibitor. It can inhibit type IV collagenase and type I collagenase with ID50 (μmol/L) of 0.3 and 1.2, respectively. It has anti-gram-positive bacteria effect. Synonyms: N-Acetyl-S-(4-(((hexahydro-2-(2-(2-(hydroxyamino)-2-oxoethyl)-1-oxoheptyl)-3-pyridazinyl)carbonyl)amino)-5-methyl-3-oxoheptyl)-L-cysteine; N-acetyl-S-(4-(2-(2-(2-(hydroxyamino)-2-oxoethyl)heptanoyl)hexahydropyridazine-3-carboxamido)-5-methyl-3-oxoheptyl)-L-cysteine. CAS No. 140626-94-4. Molecular formula: C27H47N5O8S. Mole weight: 601.76. | |
| Matlystatin B | It is produced by the strain of Actinomadura atramentaria. It's a Type V collagenase inhibitor. It can inhibit type IV collagenase and type I collagenase with ID50 (μmol/L) of 1.43 and 1.2, respectively. It has anti-gram-positive bacteria effect. Synonyms: 1(2H)-Pyridazinebutanamide, tetrahydro-N-hydroxy-6-[[[2-methyl-1-(1-oxopropyl)butyl]amino]carbonyl]-g-oxo-b-pentyl-, [6S-[1(S*),6R*(1R*,2R*)]]-; Matlystatin B1. CAS No. 140923-32-6. Molecular formula: C22H40N4O5. Mole weight: 440.58. | |
| Matlystatin D | It is produced by the strain of Actinomadura atramentaria. It's a Type V collagenase inhibitor. It can inhibit type IV collagenase and type I collagenase with ID50 (μmol/L) of 3.64 and 28, respectively. Synonyms: Matlystatin D1; Pyrazolo(1,2-a)pyridazin-4-ium,8-carboxy-1-(1-(((hexahydro-2-(2-(2-(hydroyamino)-2-oxoethyl)-1-oxoheptyl)-3-pyridazinyl)carbonyl)amino)-2-methylbutyl)-5,6,7,8-tetrahydro-,hydroxide,inner salt; [(3-{6-[{[1-(8-Carboxy-5,6,7,8-tetrahydropyrazolo[1,2-a]pyridazin-9-ium-1-yl)-2-methylbutyl]imino}(hydroxy)methyl]-1,2-diazinane-1-carbonyl}-1-hydroxyoctylidene)amino]oxidanide. CAS No. 140638-25-1. Molecular formula: C27H44N6O6. Mole weight: 548.68. | |
| Matlystatin E | It is produced by the strain of Actinomadura atramentaria. It's a Type V collagenase inhibitor. It can inhibit type IV collagenase and type I collagenase with ID50 (μmol/L) of 19.3 and 59, respectively. Synonyms: Matlystatin E1; Pyrazolo(1,2-a)pyridazin-4-ium,8-carboxy-1-(1-(((hexahydro-2-(2-(2-(hydroxyamino)-2-oxoethyl)-1-oxohexyl)-3-pyridazinyl)carbonyl)amino)-2-methylbutyl)-5,6,7,8-tetrahydro-,hydroxide,inner salt; [(3-{6-[{[1-(8-Carboxy-5,6,7,8-tetrahydropyrazolo[1,2-a]pyridazin-9-ium-1-yl)-2-methylbutyl]imino}(hydroxy)methyl]-1,2-diazinane-1-carbonyl}-1-hydroxyheptylidene)amino]oxidanide. CAS No. 140638-26-2. Molecular formula: C26H42N6O6. Mole weight: 534.65. | |
| Matlystatin F | It is produced by the strain of Actinomadura atramentaria. It's a Type V collagenase inhibitor. It can inhibit type IV collagenase and type I collagenase with ID50 (μmol/L) of 1.82 and 5.1, respectively. Synonyms: Matlystatin F1; Pyrazolo(1,2-a)pyridazin-4-ium,5-carboxy-1-(1-(((hexahydro-2-(2-(2-(hydroyamino)-2-oxoethyl)-1-oxoheptyl)-3-pyridazinyl)carbonyl)amino)-2-methylbutyl)-5,6,7,8-tetrahydro-,hydroxide,inner salt; [(3-{6-[{[1-(5-Carboxy-5,6,7,8-tetrahydropyrazolo[1,2-a]pyridazin-9-ium-1-yl)-2-methylbutyl]imino}(hydroxy)methyl]-1,2-diazinane-1-carbonyl}-1-hydroxyoctylidene)amino]oxidanide. CAS No. 140667-42-1. Molecular formula: C27H44N6O6. Mole weight: 548.68. | |
| MC-031 | MC-031, an inhibitor of cholesterol biosynthesis, is produced by the strain of Streptomyces sp. A3761. It inhibited the synthesis of cholesterol from Mevalonic acid with IC50 of 10.6×10-5 mol/L. It also showed weak anti-gram-positive bacteria activity and inhibited the growth of HL-60 cells. Synonyms: O-Demethylchlorothricin. CAS No. 134637-04-0. Molecular formula: C49H61ClO16. Mole weight: 941.45. | |
| MC-032 | MC-032, an inhibitor of cholesterol biosynthesis, is produced by the strain of Streptomyces sp. A3761. It inhibited the synthesis of cholesterol from Mevalonic acid with IC50 of 10.5×10-5 mol/L. It also showed weak anti-gram-positive bacteria activity and inhibited the growth of HL-60 cells. Synonyms: O-Demethylhydroxychlorothricin. CAS No. 134615-17-1. Molecular formula: C49H61ClO17. Mole weight: 957.45. | |
| MC-033 | MC-033, an inhibitor of cholesterol biosynthesis, is produced by the strain of Streptomyces sp. A3761. It inhibited the synthesis of cholesterol from Mevalonic acid with IC50 of 1.06×10-5 mol/L. It also showed weak anti-gram-positive bacteria activity and inhibited the growth of HL-60 cells. Synonyms: MC 033; Chlorothricin, 3B-O-de(3-chloro-6-methoxy-2-methylbenzoyl)-, 4B-(3-chloro-6-methoxy-2-methylbenzoate). CAS No. 134615-15-9. Molecular formula: C49H61ClO16. Mole weight: 941.45. | |
| MC-034 | MC-034, an inhibitor of cholesterol biosynthesis, is produced by the strain of Streptomyces sp. A3761. It inhibited the synthesis of cholesterol from Mevalonic acid with IC50 of 18.3×10-5 mol/L. It also showed weak anti-gram-positive bacteria activity and inhibited the growth of HL-60 cells. Synonyms: MC 034; Chlorothricin, 3B-O-de(3-chloro-6-methoxy-2-methylbenzoyl)-2A-hydroxy-, 4B-(3-chloro-6-methoxy-2-methylbenzoate). CAS No. 134615-16-0. Molecular formula: C49H61ClO17. Mole weight: 957.45. | |
| Megalomicin | Megalomicins are a family of macrolide antibiotics produced by the soil bacterium Micromonospora megalomicea. They exhibit antiparasitic, antiviral and antibacterial activity, and are effective against both Gram-positive and Gram-negative bacteria. CAS No. 129428-69-9. | |
| Megalomicin B | It is produced by the strain of Micromonospora megalomice var. megalomicea NRRL 3274. It is a macrolide antibiotic. It has anti-bacterial and mycobacterium activity, the activity is the strongest under alkaline condition, serum can reduce the activity of 20%-30%. It has protective effect on mice infected with Staphylococcus aureus or pneumococcus. Synonyms: W-847-B; 4'-Acetylmegalomycin A; Antibiotic XK-41B1; Megalomycin A 4'-O-acetate; XK-41-B1. CAS No. 49669-75-2. Molecular formula: C46H82N2O16. Mole weight: 919.15. | |
| Megalomicin C1 | It is produced by the strain of Micromonospora megalomice var. megalomicea NRRL 3274. It is a macrolide antibiotic. It has anti-bacterial and mycobacterium activity, the activity is the strongest under alkaline condition, serum can reduce the activity of 20%-30%. It has protective effect on mice infected with Staphylococcus aureus or pneumococcus. Synonyms: Antibiotic XK 41 C1; Antibiotic W847 C1. CAS No. 49669-76-3. Molecular formula: C48H84N2O17. Mole weight: 961.18. | |
| Megalomicin C2 | It is produced by the strain of Micromonospora megalomice var. megalomicea NRRL 3274. It is a macrolide antibiotic. It has anti-bacterial and mycobacterium activity, the activity is the strongest under alkaline condition, serum can reduce the activity of 20%-30%. It has protective effect on mice infected with Staphylococcus aureus or pneumococcus. Synonyms: Antibiotic XK 41 C2; Antibiotic W847 C2. CAS No. 49669-77-4. Molecular formula: C49H86N2O17. Mole weight: 975.21. | |
| Megapicrolichenic acid | Megapicrolichenic acid is a compound obtained from the lichen pertusaria truncata. CAS No. 157241-01-5. Molecular formula: C31H42O7. Mole weight: 526.66. | |
| Megovalicin B | It is produced by the strain of Myxococcus flavescens No. 154. It has the effect against subtilis and Escherichia coli. Megovalicin H shows the strongest antibacterial activity among the 6 components. Synonyms: Myxovirescin B; 1-Oxa-4-azacyclooctacosa-12,14,26-triene-3,20,28-trione,16-ethyl-6,8,9-trihydroxy-12-(methoxymethyl)-25,27-dimethyl-2-propyl-, (2S,6S,8S,9R,12Z,14E,16R,25R,26E)-; Myxovirescin A1, 2,3-didehydro-; 1-Oxa-4-azacyclooctacosa-12,14,26-triene-3,20,28-trione,16-ethyl-6,8,9-trihydroxy-12-(methoxymethyl)-25,27-dimethyl-2-propyl-, [2S-(2R*,6R*,8R*,9S*,12Z,14E,16S*,25S*,26E)]-; Antibiotic M 230B. CAS No. 89759-26-2. Molecular formula: C35H59NO8. Mole weight: 621.85. | |
| Megovalicin G | It is produced by the strain of Myxococcus flavescens No. 154. It has an effect against subtilis and Escherichia coli, and it also has the effect against Pseudomonas aeruginosa. Megovalicin H shows the strongest antibacterial activity among the 6 components. Molecular formula: C35H61NO7. Mole weight: 607.86. | |
| Megovalicin H | It is produced by the strain of Myxococcus flavescens No. 154. It has an effect against subtilis and Escherichia coli, and it also has the effect against Pseudomonas aeruginosa. Megovalicin H shows the strongest antibacterial activity among the 6 components. Synonyms: Myxovirescin C1; 1-Oxa-4-azacyclooctacosa-12,14-diene-3,28-dione,16-ethyl-6,8,9-trihydroxy-12-(methoxymethyl)-25,27-dimethyl-2-propyl-, (2S,6S,8S,9R,12Z,14E,16R,25R,27S)-; Myxovirescin A1, 9-deoxo-; 1-Oxa-4-azacyclooctacosa-12,14-diene-3,28-dione,16-ethyl-6,8,9-trihydroxy-12-(methoxymethyl)-25,27-dimethyl-2-propyl-, [2S-(2R*,6R*,8R*,9S*,12Z,14E,16S*,25S*,27R*)]-. CAS No. 115932-37-1. Molecular formula: C35H63NO7. Mole weight: 609.88. | |
| Melacarpic acid | It has been shown to be a constituent of the Australian lichen Gymnoderma melacarpum (Wils.) Yoshim. Synonyms: 2-Dibenzofurancarboxylic acid, 1-heptyl-3-hydroxy-7-methoxy-9-methyl-; 1-heptyl-3-hydroxy-7-methoxy-9-methyldibenzofuran-2-carboxylic acid. CAS No. 74683-09-3. Molecular formula: C22H26O5. Mole weight: 370.44. | |
| Melanocin A | It is produced by the strain of Eupenicillium shearii F80965. It is a Melanin biosynthesis inhibitor. It inhibits the biosynthesis of melanin and tyrosinase (IC50 is 9.0 nmol/L, MIC is 0.9 μmol/L). It also has antioxidant effect. Molecular formula: C18H14N2O5. Mole weight: 338.31. | |
| Melanocin B | It is produced by the strain of Eupenicillium shearii F80965. It does not inhibit the biosynthesis of melanin and tyrosinase. It has antioxidant effect. Molecular formula: C17H15NO6. Mole weight: 329.30. | |
| Melanocin C | It is produced by the strain of Eupenicillium shearii F80965. It does not inhibit the biosynthesis of melanin and tyrosinase. It has antioxidant effect. Molecular formula: C18H14N2O6. Mole weight: 354.31. | |
| Melanoxazal | It is produced by the strain of Trichoderma sp. ATF-451. It is a Melanin biosynthesis inhibitor. It can inhibit melanin formation in the silkworm larva hemolymph (IC50 is 30.1 μg/mL), and also has stronger inhibitory effect against mushroom tyrosinase (IC50 is 4.2 μg/mL), but it has no antimicrobial effect. Molecular formula: C8H9NO3. Mole weight: 167.16. | |
| Melinacidin IV | It is produced by the strain of Verticillium tenerum. It is similar to Chaetocin and has anti-gram-positive bacterial and HeLa cell activity. Synonyms: 11,11'-Dihydroxychaetocin; (6S,6'S)-6,6'-Dihydroxychaetocin; Chetocin, 11,11'-dihydroxy-; Chaetocin, 6,6'-dihydroxy-, (6S,6'S)-; 11α,11'α-Dihydroxychactocin. CAS No. 37934-52-4. Molecular formula: C30H28N6O8S4. Mole weight: 728.84. | |
| Melithiazol A | Melithiazol A is an antibiotic produced by Melittangium lichenicila Mel26, Archangium gephyra Ar 7747 and Myxococcus stipitatus Mx s 64. It is a β-methoxyacrylate (MOA) inhibitor with strong anti-agent activity. Antifungal and cytotoxic agent. Synonyms: Melithiazole A. CAS No. 170894-30-1. Molecular formula: C20H26N2O4S2. Mole weight: 422.56. | |
| Melithiazol B | Melithiazol B is an antibiotic produced by Melittangium lichenicila Mel26, Archangium gephyra Ar 7747 and Myxococcus stipitatus Mx s 64. It is a β-methoxyacrylate (MOA) inhibitor with strong anti-agent activity. Antifungal and cytotoxic agent. Synonyms: Melithiazole B. CAS No. 170894-31-2. Molecular formula: C20H24N2O4S2. Mole weight: 420.54. | |
| Melithiazol C | Melithiazol C is an antibiotic produced by Melittangium lichenicila Mel26, Archangium gephyra Ar 7747 and Myxococcus stipitatus Mx s 64. It is a β-methoxyacrylate (MOA) inhibitor with strong anti-agent activity. Antifungal agent. Synonyms: Melithiazole C; Melithiazol-C. CAS No. 214420-47-0. Molecular formula: C16H21NO5S. Mole weight: 339.41. | |
| Melithiazol D | Melithiazol D is an antibiotic produced by Melittangium lichenicila Mel26, Archangium gephyra Ar 7747 and Myxococcus stipitatus Mx s 64. It is a β-methoxyacrylate (MOA) inhibitor with strong anti-agent activity. CAS No. 248938-46-7. Molecular formula: C20H28N2O4S2. Mole weight: 424.58. | |
| Melithiazol I | Melithiazol I is an antibiotic produced by Melittangium lichenicila Mel26, Archangium gephyra Ar 7747 and Myxococcus stipitatus Mx s 64. It is a β-methoxyacrylate (MOA) inhibitor with strong anti-agent activity. CAS No. 248938-52-5. Molecular formula: C21H28N2O4S2. Mole weight: 436.59. | |
| Melithiazol K | Melithiazol K is an antibiotic produced by Melittangium lichenicila Mel26, Archangium gephyra Ar 7747 and Myxococcus stipitatus Mx s 64. It is a β-methoxyacrylate (MOA) inhibitor with strong anti-agent activity. Synonyms: Melithiazole K. CAS No. 248938-47-8. Molecular formula: C20H26N2O5S2. Mole weight: 438.56. | |
| Melithiazol N | Melithiazol N is an antibiotic produced by Melittangium lichenicila Mel26, Archangium gephyra Ar 7747 and Myxococcus stipitatus Mx s 64. It is a β-methoxyacrylate (MOA) inhibitor with strong anti-agent activity. Synonyms: Melithiazole N. CAS No. 248938-54-7. Molecular formula: C20H24N2O5S2. Mole weight: 436.54. | |
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